BCHE - butyrylcholinesterase Gene
Species: Macaca mulatta
Gene Type: protein coding
Gene ID: 700484
About BCHE
Primary_assembly 2: 70,371,218-70,440,183 reverse strand.Mmul_10:CM014337.1
This gene has 2 transcripts (splice variants), 130 orthologues and 11 paralogues.
BCHE Products (4)
| mRNA | Protein | Name |
|---|---|---|
| XM_002808333.3 | XP_002808379.2 | cholinesterase isoform X1 |
| XM_015131685.2 | XP_014987171.1 | cholinesterase isoform X2 |
| XM_015131685.2 | XP_014987171.1 | cholinesterase isoform X2 |
| XM_002808333.3 | XP_002808379.2 | cholinesterase isoform X1 |
BCHE Protein Structure
COesterase
COesterase: pfam00135 (29 - 549)
AChE_tetra
AChE_tetra: pfam08674 (564 - 598)
- 0
- 100
- 200
- 300
- 400
- 500
- 602 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
cholinesterase |
|
|
Related Agents
- Approval
- Pre-clinical Phase
Approval
Bioactive Molecules
(9)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-17368 | Rivastigmine | Inhibitor | 99.95% | Yes |
| HY-B1488 | Tacrine hydrochloride | Inhibitor | 99.90% | Unkown |
| HY-107922 | Ethopropazine hydrochloride | Inhibitor | 99.32% | Unkown |
| HY-B1239 | Drofenine hydrochloride | Inhibitor | 98.10% | Unkown |
| HY-100919 | Ambenonium chloride | Inhibitor | 96.18% | Yes |
| HY-B2244 | Tacrine hydrochloride hydrate | Inhibitor | 99.98% | Unkown |
| HY-B1542A | Benactyzine hydrochloride | Inhibitor | 99.02% | Unkown |
| HY-B1239A | Drofenine | Inhibitor | / | Unkown |
| HY-16183 | Echothiopate iodide | Inhibitor | / | Unkown |
Pre-clinical Phase
Bioactive Molecules
(196)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-N0285 | Imperatorin | Inhibitor | 98.59% | Unkown |
| HY-107569 | Garcinol | Inhibitor | 98.85% | Unkown |
| HY-N0226A | Epiberberine chloride | Inhibitor | 98.68% | Unkown |
| HY-N0631 | Cornuside | Inhibitor | 99.99% | Unkown |
| HY-N4225 | Aaptamine | Inhibitor | 99.71% | Unkown |
| HY-W130025 | p-Xylene bispyridinium bromide | Inhibitor | 99.60% | Unkown |
| HY-122140 | ACG548B | Inhibitor | 99.72% | Unkown |
| HY-N2157 | Pteryxin | Inhibitor | 99.55% | Unkown |
| HY-N2129 | N-Nornuciferine | Inhibitor | 99.94% | Unkown |
| HY-121382 | Gypsogenin | Inhibitor | 99.51% | Unkown |
| HY-W130236 | Methylene Violet 3RAX | Inhibitor | 95.54% | Unkown |
| HY-121072 | ASS234 | Inhibitor | 99.6% | Unkown |
| HY-107275 | Ebeiedinone | Inhibitor | 99.51% | Unkown |
| HY-119577 | Ubretid | 99.0% | Yes | |
| HY-155140 | BChE-IN-17 | Inhibitor | 99.07% | Unkown |
| HY-N2284 | Sophoflavescenol | Inhibitor | 98.78% | Unkown |
| HY-N7263 | Galanthamine N-Oxide | Inhibitor | 99.90% | Unkown |
| HY-N12581 | Kuwanon U | Inhibitor | 97.30% | Unkown |
| HY-P11392 | Ac-IEAR-pNA | Substrate | 99.82% | Unkown |
| HY-N0226 | Epiberberine | Inhibitor | 98.46% | Unkown |
| HY-N10488 | BChE-IN-11 | Inhibitor | 98.78% | Unkown |
| HY-149212 | SD-6 | Inhibitor | ≥98.0% | Unkown |
| HY-151368 | AChE/BChE-IN-10 | Inhibitor | 99.67% | Unkown |
| HY-103373 | PE154 | Inhibitor | 99.01% | Unkown |
| HY-N2960 | Broussonin A | Inhibitor | 97% | Unkown |
| HY-N7346 | Lucidadiol | Inhibitor | 98.0% | Unkown |
| HY-W185336 | Dibutyl phenyl phosphate | Inhibitor | 98.06% | Unkown |
| HY-162340 | Z32439948 | Inhibitor | / | Unkown |
| HY-131971 | AChE/BChE-IN-1 | Inhibitor | / | Unkown |
| HY-151436 | ZLMT-12 | Inhibitor | / | Unkown |
| HY-146663A | AChE/BChE-IN-3 hydrochloride | Inhibitor | / | Unkown |
| HY-168052 | hAChE-IN-9 | Inhibitor | / | Unkown |
| HY-159143 | BChE-IN-33 | Inhibitor | / | Unkown |
| HY-N18289 | 8-Hydroxydihydrochelerythrine | Inhibitor | / | Unkown |
| HY-184159 | AChE/BChE/MAO-A-IN-2 | Inhibitor | / | Unkown |
| HY-180819 | AChE/BChE-IN-33 | Inhibitor | / | Unkown |
| HY-149090 | AChE/BuChE/MAO-B-IN-2 | / | Unkown | |
| HY-169163 | BChE-IN-36 | Inhibitor | / | Unkown |
| HY-156031 | BChE-IN-19 | Inhibitor | / | Unkown |
| HY-108048 | Desoxypeganine | Inhibitor | / | Unkown |
| HY-162639 | α-Glucosidase-IN-68 | Inhibitor | / | Unkown |
| HY-N10781 | Isograndifoliol | Inhibitor | / | Unkown |
| HY-151405 | Z164597606 | Inhibitor | / | Unkown |
| HY-N15710 | Magnotriol B | Inhibitor | / | Unkown |
| HY-143465 | BChE-IN-5 | Inhibitor | / | Unkown |
| HY-163883 | BChE-IN-34 | Inhibitor | / | Unkown |
| HY-157978 | AChE-IN-59 | Inhibitor | / | Unkown |
| HY-149300 | SB-1436 | Inhibitor | / | Unkown |
| HY-183798 | BChE/MAO-B-IN-6 | Inhibitor | / | Unkown |
| HY-155284 | K1833 | Inhibitor | / | Unkown |
| HY-161156 | BChE-IN-26 | Inhibitor | / | Unkown |
| HY-182615 | Cymserine | Inhibitor | / | Unkown |
| HY-159898 | AChE/BChE-IN-23 | Inhibitor | / | Unkown |
| HY-183760 | AChE/BChE-IN-37 | Inhibitor | / | Unkown |
| HY-158092 | ChEs/MAOs-IN-2 | Inhibitor | / | Unkown |
| HY-172782 | BuChE-IN-20 | Inhibitor | / | Unkown |
| HY-183750 | BChE reactivator-1 | / | Unkown | |
| HY-172219 | CUR-IPA | Inhibitor | / | Unkown |
| HY-180243 | AChE-IN-102 | Inhibitor | / | Unkown |
| HY-163909 | AChE-IN-72 | Inhibitor | / | Unkown |
| HY-157437 | AChE/BChE-IN-16 | Inhibitor | / | Unkown |
| HY-N17425 | Lakoochin C | Inhibitor | / | Unkown |
| HY-170938 | AChE-IN-82 | Inhibitor | / | Unkown |
| HY-W800535 | Cryptolepine | Inhibitor | / | Unkown |
| HY-180892 | Multi-kinase-IN-10 | Inhibitor | / | Unkown |
| HY-144689 | BChE-IN-3 | Inhibitor | / | Unkown |
| HY-180797 | S1R agonist/BChE-IN-1 | Inhibitor | / | Unkown |
| HY-181597 | LINS05414 | Inhibitor | / | Unkown |
| HY-182290 | AChE/BChE-IN-36 | Inhibitor | / | Unkown |
| HY-149993 | hBChE-IN-2 | Inhibitor | / | Unkown |
| HY-146251 | BuChE-IN-6 | Inhibitor | / | Unkown |
| HY-159880 | AChE/BChE-IN-24 | Inhibitor | / | Unkown |
| HY-182254 | AChE/BChE-IN-35 | Inhibitor | / | Unkown |
| HY-N10701 | AChE/BChE-IN-11 | Inhibitor | / | Unkown |
| HY-161331 | S16–1029 | Inhibitor | / | Unkown |
| HY-178433 | BChE/p38-α MAPK-IN-2 | Inhibitor | / | Unkown |
| HY-179363 | BChE-IN-46 | Inhibitor | / | Unkown |
| HY-161512 | hAChE/hBACE-1-IN-4 | Inhibitor | / | Unkown |
| HY-D3171 | AD-BChE/HClO | / | Unkown | |
| HY-149288 | hAChE/hBACE-1-IN-2 | Inhibitor | / | Unkown |
| HY-168301 | CL-13 | Inhibitor | / | Unkown |
| HY-179711 | AChE/BChE-IN-32 | Inhibitor | / | Unkown |
| HY-107272 | Chuanbeinone | Inhibitor | / | Unkown |
| HY-157981 | AChE-IN-60 | Inhibitor | / | Unkown |
| HY-N10490 | Blestrin D | Inhibitor | / | Unkown |
| HY-N10489 | BChE-IN-12 | Inhibitor | / | Unkown |
| HY-175523 | MAO-B-IN-48 | Inhibitor | / | Unkown |
| HY-175658 | AChE/BChE-IN-29 | Inhibitor | / | Unkown |
| HY-162812 | H3R antagonist 4 | Inhibitor | / | Unkown |
| HY-181248 | BChE-IN-49 | Inhibitor | / | Unkown |
| HY-174464 | AChE/BChE-IN-28 | Inhibitor | / | Unkown |
| HY-161643 | S21-1011 | Inhibitor | / | Unkown |
| HY-183352 | BuChE-IN-23 | Inhibitor | / | Unkown |
| HY-173152 | AChE/BChE-IN-26 | Inhibitor | / | Unkown |
| HY-169961 | BChE-IN-38 | Inhibitor | / | Unkown |
| HY-158334 | NDs-IN-1 | Inhibitor | / | Unkown |
| HY-155085 | hAChE-IN-3 | Inhibitor | / | Unkown |
| HY-170417 | hAChE/hBuChE/GSK-3β-IN-1 | Inhibitor | / | Unkown |
| HY-180552 | AChE-IN-104 | Inhibitor | / | Unkown |
| HY-119292 | AP2238 | Inhibitor | / | Unkown |
| HY-146669 | BChE-IN-6 | Inhibitor | / | Unkown |
| HY-159482 | SBN-284 | Inhibitor | / | Unkown |
| HY-149243 | BChE-IN-16 | Inhibitor | / | Unkown |
| HY-180146 | BChE-IN-48 | Inhibitor | / | Unkown |
| HY-150545 | AChE-IN-21 | Inhibitor | / | Unkown |
| HY-181167 | AChE/BChE-IN-34 | Inhibitor | / | Unkown |
| HY-163441 | BChE-IN-31 | Inhibitor | / | Unkown |
| HY-169162 | hBChE-IN-3 | Inhibitor | / | Unkown |
| HY-182786 | MAO-B-IN-56 | Inhibitor | / | Unkown |
| HY-144762 | K027 | Inhibitor | / | Unkown |
| HY-163746 | BuChE-IN-11 | Inhibitor | / | Unkown |
| HY-162671 | BuChE-IN-12 | Inhibitor | / | Unkown |
| HY-149087 | MR2938 | Inhibitor | / | Unkown |
| HY-179496 | ChE/GSK-3β-IN-1 | Inhibitor | / | Unkown |
| HY-161453 | BChE-IN-32 | Inhibitor | / | Unkown |
| HY-149272 | tau/Aβ40 aggregation-IN-1 | Inhibitor | / | Unkown |
| HY-175211 | BChE-IN-42 | Inhibitor | / | Unkown |
| HY-152632 | BuChE-IN-7 | Inhibitor | / | Unkown |
| HY-169234 | BChE-IN-35 | Inhibitor | / | Unkown |
| HY-153432 | TRV-7019 | 99.64% | Unkown | |
| HY-108048A | Desoxypeganine hydrochloride | Inhibitor | / | Unkown |
| HY-178017 | BChE/hCA II-IN-1 | Inhibitor | / | Unkown |
| HY-157384 | BChE-IN-22 | Inhibitor | / | Unkown |
| HY-174399 | AChE/BChE-IN-27 | Inhibitor | / | Unkown |
| HY-127087 | Isogarcinol | Inhibitor | / | Unkown |
| HY-179726 | BChE-IN-47 | Inhibitor | / | Unkown |
| HY-161508 | AChE/BChE-IN-19 | Inhibitor | / | Unkown |
| HY-175655 | BChE/p38-α MAPK-IN-1 | Inhibitor | / | Unkown |
| HY-170976 | BuChE-IN-16 | / | Unkown | |
| HY-158261 | AChE-IN-63 | Inhibitor | / | Unkown |
| HY-168731 | AChE/BChE-IN-25 | Inhibitor | / | Unkown |
| HY-114422 | p38α-IN-13 | Inhibitor | / | Unkown |
| HY-155366 | hAChE-IN-6 | Inhibitor | / | Unkown |
| HY-183303 | AChE-IN-116 | Inhibitor | / | Unkown |
| HY-162681 | eeAChE-IN-3 | Inhibitor | / | Unkown |
| HY-162693 | AChE-IN-68 | Inhibitor | / | Unkown |
| HY-175973 | AChE/BChE-IN-30 | Inhibitor | / | Unkown |
| HY-118729 | Difeterol | Inhibitor | / | Unkown |
| HY-182001 | Multi-kinase-IN-13 | Inhibitor | / | Unkown |
| HY-149287 | hAChE/hBACE-1-IN-1 | Inhibitor | / | Unkown |
| HY-163514 | hAChE-IN-8 | Inhibitor | / | Unkown |
| HY-158696 | BChE/MAO-B-IN-1 | Inhibitor | / | Unkown |
| HY-161150 | AChE/BChE-IN-17 | Inhibitor | / | Unkown |
| HY-175524 | BChE/MAO-B-IN-2 | Inhibitor | / | Unkown |
| HY-180783 | AChE/BChE/MAO-A-IN-1 | Inhibitor | / | Unkown |
| HY-152232 | BChE-IN-15 | Inhibitor | / | Unkown |
| HY-162338 | BChE-IN-29 | Inhibitor | / | Unkown |
| HY-152113 | AChE/BChE/MAO-B-IN-3 | Inhibitor | / | Unkown |
| HY-158978 | Multitarget AD inhibitor-2 | Inhibitor | / | Unkown |
| HY-147939 | AChE/BuChE-IN-3 | Inhibitor | / | Unkown |
| HY-179122 | BChE-IN-45 | Inhibitor | / | Unkown |
| HY-161507 | hCAI/II-IN-8 | Inhibitor | / | Unkown |
| HY-169962 | hCA I-IN-4 | Inhibitor | / | Unkown |
| HY-N19871 | Monogynol A | Inhibitor | / | Unkown |
| HY-N2129A | N-Nornuciferine hydrochloride | Inhibitor | / | Unkown |
| HY-151562 | AChE/BuChE/MAO-B-IN-1 | Inhibitor | / | Unkown |
| HY-181445 | NSC 620023 TFA | Inhibitor | / | Unkown |
| HY-181503 | AChE/BuChE-IN-8 | Inhibitor | / | Unkown |
| HY-181865 | BuChE-IN-22 | Inhibitor | / | Unkown |
| HY-179126 | BChE/MAO-A-IN-1 | Inhibitor | / | Unkown |
| HY-121191 | Bisnorcymserine | Inhibitor | / | Unkown |
| HY-170561 | AChE/BuChE-IN-6 | Inhibitor | / | Unkown |
| HY-150585 | BuChE-IN-5 | Inhibitor | / | Unkown |
| HY-172460 | AChE/BChE/MAO-B-IN-5 | Inhibitor | / | Unkown |
| HY-162036 | α-Amylase/α-Glucosidase-IN-7 | Inhibitor | / | Unkown |
| HY-180891 | Multitarget AD-IN-4 | Inhibitor | / | Unkown |
| HY-152112 | AChE/BChE/MAO-B-IN-2 | Inhibitor | / | Unkown |
| HY-157382 | AChE-IN-51 | Inhibitor | / | Unkown |
| HY-157982 | BChE-IN-28 | Inhibitor | / | Unkown |
| HY-185347 | AChE-IN-114 | Inhibitor | / | Unkown |
| HY-N10486 | BChE-IN-10 | Inhibitor | / | Unkown |
| HY-N9846 | Luteolin 5,3'-dimethyl ether | / | Unkown | |
| HY-172461 | MAO-IN-6 | Inhibitor | / | Unkown |
| HY-149211 | AChE/BChE-IN-12 | Inhibitor | / | Unkown |
| HY-161842 | AChE-IN-67 | Inhibitor | / | Unkown |
| HY-159081 | AChE/BChE-IN-20 | Inhibitor | / | Unkown |
| HY-163537 | AChE/BuChE-IN-5 | Inhibitor | / | Unkown |
| HY-178356 | BChE-IN-44 | Inhibitor | / | Unkown |
| HY-146315 | AChE/BChE-IN-6 | Inhibitor | / | Unkown |
| HY-174328 | BChE/AChE-IN-1 | Inhibitor | / | Unkown |
| HY-184292 | COX-2-IN-67 | Inhibitor | / | Unkown |
| HY-181851 | AChE-IN-109 | Inhibitor | / | Unkown |
| HY-W746884 | 2-Methyl-2-butenyl (E)-Caffeate | Inhibitor | / | Unkown |
| HY-149273 | hBChE-IN-1 | Inhibitor | / | Unkown |
| HY-170389 | BChE-IN-39 | Inhibitor | / | Unkown |
| HY-146687 | BuChE-IN-4 | Inhibitor | / | Unkown |
| HY-178943 | Neuroprotective agent 15 | Inhibitor | / | Unkown |
| HY-144446 | BuChE-IN-1 | Inhibitor | / | Unkown |
| HY-181041 | Multitarget AD-IN-5 | Inhibitor | / | Unkown |
| HY-159977 | 1,2-Didehydrotanshinone IIA | Inhibitor | / | Unkown |
| HY-W332450 | Demeton-S | Inhibitor | / | Unkown |
| HY-W049312 | 7-Methoxytacrine | Inhibitor | / | Unkown |
| HY-B1542 | Benactyzine | Inhibitor | / | Unkown |
| HY-N1151 | Thunberginol C | Inhibitor | / | Unkown |
| HY-N19401 | Vescalagin | Inhibitor | / | Unkown |
| HY-183403 | Ganstigmine | Inhibitor | / | Unkown |
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