CDK1 - cyclin dependent kinase 1 Gene

Also Known as CDC2; CDC28A; P34CDC2

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 983

About CDK1

Cytogenetic location: 10q21.2 Genomic coordinates (GRCh38): 10:60,778,331-60,794,852 (from NCBI)

This gene has 8 transcripts (splice variants), 246 orthologues and 26 paralogues. Broad expression in lymph node (RPKM 12.8), bone marrow (RPKM 12.8) and 18 other tissues.

Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

CDK1 Products (7)

mRNA	Protein	Name
NM_001786.5	NP_001777.1	cyclin-dependent kinase 1 isoform 1
XM_005270303.4	XP_005270360.1	cyclin-dependent kinase 1 isoform X1
NM_001170406.1	NP_001163877.1	cyclin-dependent kinase 1 isoform 4
NM_001320918.1	NP_001307847.1	cyclin-dependent kinase 1 isoform 1
NM_001170407.2	NP_001163878.1	cyclin-dependent kinase 1 isoform 4
NM_001130829.1
NM_033379.5	NP_203698.1	cyclin-dependent kinase 1 isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Referencias	Source
enables RNA polymerase II CTD heptapeptide repeat kinase activity	IDA IDA: Inferred from direct assay	12721286	GOA
enables cyclin binding	IDA IDA: Inferred from direct assay	7739547	GOA
enables cyclin binding	IPI IPI: Inferred from physical interaction	1312467	GOA
enables cyclin-dependent protein kinase activity	IDA IDA: Inferred from direct assay	1312467	GOA
enables cyclin-dependent protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	2188730	GOA
enables cyclin-dependent protein serine/threonine kinase activity	IMP IMP: Inferred from mutant phenotype	24746669	GOA
enables histone kinase activity	IDA IDA: Inferred from direct assay	21871177	GOA
enables kinase activity	IDA IDA: Inferred from direct assay	28575661	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	7815540	GOA
enables protein kinase activity	IDA IDA: Inferred from direct assay	22854038	GOA
enables protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	7588608	GOA

Biological Process GO Annotation	Evidence	Referencias	Source
involved in DNA damage response	IDA IDA: Inferred from direct assay	19202191	GOA
involved in G2/M transition of mitotic cell cycle	IDA IDA: Inferred from direct assay	2188730	GOA
involved in epithelial cell differentiation	IEP IEP: Inferred from expression pattern	21492153	GOA
involved in microtubule cytoskeleton organization involved in mitosis	IDA IDA: Inferred from direct assay	10791892	GOA
involved in mitotic nuclear membrane disassembly	IDA IDA: Inferred from direct assay	2188730	GOA
involved in negative regulation of apoptotic process	IDA IDA: Inferred from direct assay	11069302	GOA
involved in peptidyl-serine phosphorylation	IDA IDA: Inferred from direct assay	11298763	GOA
involved in peptidyl-threonine phosphorylation	IDA IDA: Inferred from direct assay	11298763	GOA
involved in peptidyl-threonine phosphorylation	IMP IMP: Inferred from mutant phenotype	27238018	GOA
involved in positive regulation of G2/M transition of mitotic cell cycle	IMP IMP: Inferred from mutant phenotype	24746669	GOA
involved in positive regulation of mitochondrial ATP synthesis coupled electron transport	IMP IMP: Inferred from mutant phenotype	24746669	GOA
involved in positive regulation of mitotic sister chromatid segregation	IDA IDA: Inferred from direct assay	26829474	GOA
involved in positive regulation of protein localization to nucleus	IMP IMP: Inferred from mutant phenotype	21871177	GOA
involved in protein localization to kinetochore	IDA IDA: Inferred from direct assay	18195732	GOA
involved in protein localization to kinetochore	IMP IMP: Inferred from mutant phenotype	28479321	GOA
involved in regulation of attachment of mitotic spindle microtubules to kinetochore	IDA IDA: Inferred from direct assay	28479321	GOA
involved in regulation of circadian rhythm	IMP IMP: Inferred from mutant phenotype	27238018	GOA

Cellular Component GO Annotation	Evidence	Referencias	Source
located in centrosome	IDA IDA: Inferred from direct assay	17488717	GOA
part of cyclin B1-CDK1 complex	IMP IMP: Inferred from mutant phenotype	24746669	GOA
part of cyclin B1-CDK1 complex	IPI IPI: Inferred from physical interaction	17495531	GOA
part of cyclin-dependent protein kinase holoenzyme complex	IDA IDA: Inferred from direct assay	1312467	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	15767402	GOA
located in midbody	IDA IDA: Inferred from direct assay	11069302	GOA
colocalizes with mitochondrial matrix	IDA IDA: Inferred from direct assay	24746669	GOA
located in mitotic spindle	IDA IDA: Inferred from direct assay	17488717	GOA
located in nucleus	IDA IDA: Inferred from direct assay	15767402	GOA
located in spindle microtubule	IDA IDA: Inferred from direct assay	11069302	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDK1 Protein Structure

Pkinase

0
100
200
297 a.a.

Protein Preferred Names	Protein Names
cyclin-dependent kinase 1	cell cycle controller CDC2 cell division control protein 2 homolog cell division cycle 2, G1 to S and G2 to M cell division protein kinase 1 p34 protein kinase

CDK1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Referencias
Intra	CDK1	P06493	FOXO1	Homo sapiens	Q12778	Anti Tag CoIP	18408765
Intra	CDK1	P06493	FOXO1	Homo sapiens	Q12778	Protein Kinase Assay	18408765
Intra	CDK1	P06493	DEDD	Homo sapiens	O75618-1	Anti Bait CoIP	17283331
Intra	CDK1	P06493	DEDD	Homo sapiens	O75618-1	Anti Tag CoIP	17283331
Intra	CDK1	P06493	UBC	Homo sapiens	P0CG48	Anti Tag CoIP	20395957
Intra	CDK1	P06493	ALYREF	Homo sapiens	Q86V81	Crosslink	29128334
Intra	CDK1	P06493	CDKN1A	Homo sapiens	P38936	Anti Tag CoIP	33961781
Intra	CDK1	P06493	CDKN1A	Homo sapiens	P38936	TAP	23602568
Intra	CDK1	P06493	CDKN1A	Homo sapiens	P38936	Anti Tag CoIP	28514442
Intra	CDK1	P06493	CDKN1A	Homo sapiens	P38936	Pull Down	32707033
Intra	CDK1	P06493	CDKN1A	Homo sapiens	P38936	Anti Tag CoIP	23543736
Intra	CDK1	P06493	LATS1	Homo sapiens	O95835	CoIP	9988268
Intra	CDK1	P06493	CKS1B	Homo sapiens	P61024	Anti Tag CoIP	25852190
Intra	CDK1	P06493	CKS1B	Homo sapiens	P61024	Anti Tag CoIP	33961781
Intra	CDK1	P06493	CKS1B	Homo sapiens	P61024	TAP	23602568
Intra	CDK1	P06493	CKS1B	Homo sapiens	P61024	MAPPIT	25416956
Intra	CDK1	P06493	CKS1B	Homo sapiens	P61024	Validated Y2H	25416956
Intra	CDK1	P06493	CKS1B	Homo sapiens	P61024	Anti Tag CoIP	26496610
Intra	CDK1	P06493	CKS1B	Homo sapiens	P61024	Y2H Prey Pooling	25416956
Intra	CDK1	P06493	CKS1B	Homo sapiens	P61024	Y2H Array	25416956
Intra	CDK1	P06493	CKS1B	Homo sapiens	P61024	Pull Down	32707033
Intra	CDK1	P06493	PKMYT1	Homo sapiens	Q99640	Anti Tag CoIP	33961781
Intra	CDK1	P06493	PKMYT1	Homo sapiens	Q99640	Anti Tag CoIP	28514442
Intra	CDK1	P06493	PKMYT1	Homo sapiens	Q99640	Anti Tag CoIP	25852190
Intra	CDK1	P06493	PKMYT1	Homo sapiens	Q99640	Protein Kinase Assay	10373560
Intra	CDK1	P06493	PKMYT1	Homo sapiens	Q99640	TAP	23602568
Intra	CDK1	P06493	PKMYT1	Homo sapiens	Q99640	Pull Down	32707033
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Protein Kinase Assay	12612082
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Protein Kinase Assay	19879842
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Pull Down	32707033
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Anti Bait CoIP	17283331
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Anti Tag CoIP	17283331
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Protein Kinase Assay	18408765
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Anti Bait CoIP	23799914
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Anti Tag CoIP	26496610
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Anti Tag CoIP	25852190
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Protein Kinase Assay	33037310
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	TAP	23602568
Intra	CDK1	P06493	CCNB1	Homo sapiens	P14635	Anti Tag CoIP	28514442
Intra	CDK1	P06493	BIRC5	Homo sapiens	O15392	IF	17681274
Intra	CDK1	P06493	CDKN1B	Homo sapiens	P46527	Anti Tag CoIP	28514442
Intra	CDK1	P06493	CDKN1B	Homo sapiens	P46527	Anti Tag CoIP	23543736
Intra	CDK1	P06493	CDKN1B	Homo sapiens	P46527	Anti Bait CoIP	24358021
Intra	CDK1	P06493	CDKN1B	Homo sapiens	P46527	Pull Down	32707033
Intra	CDK1	P06493	CDKN1B	Homo sapiens	P46527	Anti Tag CoIP	33961781
Intra	CDK1	P06493	CDKN1B	Homo sapiens	P46527	TAP	23602568
Cross	CDK1	P06493	lt_sv40	Simian virus 40	P03070	Pull Down	7815540
Intra	CDK1	P06493	EIF2AK2	Homo sapiens	P19525	Protein Kinase Assay	20395957
Intra	CDK1	P06493	TNFSF12	Homo sapiens	O43508	Y2H Array	32814053
Intra	CDK1	P06493	TNFSF12	Homo sapiens	O43508	Validated Y2H	32814053
Intra	CDK1	P06493	TNFSF12	Homo sapiens	O43508	Y2H Pooling	32814053
Intra	CDK1	P06493	CDC25C	Homo sapiens	P30307	Anti Tag CoIP	17349584

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CDK1 Proteins

Referencia número	Nombre del producto	Accession	Pureza
HY-P74257	CDK1-CCNE1 Heterodimer Protein, Human (Inactive, sf9, His-GST)	NP_001777.1 (M1-M297)& NP_001229.1 (M1-A410)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P75668	CDK1 Protein, Human (Inactive, sf9, GST)	P06493 (M1-M297)	≥ 80%, as determined by reducing SDS-PAGE.

CDK1 Antibodies

Referencia número	Nombre del producto	Aplicación	Reactivity
HY-P80611	CDK1 Antibody (YA516)	WB, IP	Human
HY-P80611A	CDK1 Antibody (YA516)(PBS only)	WB, IP	Human
HY-P80796	Phospho-CDK1 (Tyr15) Antibody	WB	Human, Mouse, Rat
HY-P80797	Phospho-CDK1/2/3 (Thr14) Antibody (YA218)	WB, IP	Human, Hamster
HY-P80797A	Phospho-CDK1/2/3 (Thr14) Antibody (YA218)(PBS only)	WB, IP	Human, Hamster
HY-P810642	Phospho-CDK (Tyr15) Antibody (YA9904)	WB, IHC-P	Human, Mouse
HY-P810643	Phospho-CDK1 (Thr161) Antibody (YA9905)	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
HY-P810644	Phospho-CDK1/2/3 (Thr14) Antibody (YA9906)	WB, IHC-P	Human, Mouse, Rat
HY-P82827	Phospho-CDK1/2 (Thr14) Antibody (YA2572)	WB, IHC-P, IP	Human
HY-P82827A	Phospho-CDK1/2 (Thr14) Antibody (YA2572)(PBS only)	WB, IHC-P, IP	Human
HY-P83973	CDK1 Antibody (YA3670)	WB, ICC/IF, FC, ELISA	Human
HY-P83973A	CDK1 Antibody (YA3670)(PBS only)	WB, ICC/IF, FC, ELISA	Human
HY-P86404	CDK1 Antibody (YA6096)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse,

Related Diseases

Diseases	Alias
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Neuroblastoma	Nb Neuroblastoma, Susceptibility To Neuroblastomas Central Neuroblastoma
Squamous Cell Carcinoma, Head And Neck	Squamous Cell Carcinoma Of The Head And Neck HNSCC Head And Neck Squamous Cell Carcinoma Head And Neck Cancer Squamous Cell Carcinoma Of Lip Squamous Cell Carcinoma, Head And Neck, Somatic Carcinoma Of The Head And Neck Squamous Cell Carcinomas Of Head And Neck Scchn Squamous Cell Carcinoma Of The Hypopharynx Squamous Cell Carcinoma Of The Oropharynx Squamous Cell Carcinoma Of Salivary Glands Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses Squamous Cell Carcinoma Of The Oral Cavity Squamous Cell Carcinoma Of The Lip Carcinoma, Squamous Cell Of Head And Neck Lip Squamous Cell Carcinoma Cancer, Head/Neck Carcinoma, Squamous Cell, Head And Neck Salivary Gland Squamous Cell Carcinoma Cancer Of Head And Neck Squamous Cell Carcinoma Of Oropharynx Nos
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Bladder Cancer	Urinary Bladder Cancer Bladder Carcinoma Urinary Bladder Carcinoma Bladder Neoplasm Bladder Tumor Cancer, Bladder Malignant Neoplasm Of Urinary Bladder Carcinoma Of Bladder Bladder Cancer, Somatic Tumor Of The Bladder Carcinoma Of Urinary Bladder Bladder Carcinoma Urinary Cancer Of The Urinary Bladder Cancer, Urinary Bladder Malignant Bladder Neoplasm Malignant Bladder Tumor Neoplasm Of The Bladder Neoplasm Of The Urinary Bladder Tumor Of The Urinary Bladder Urinary Bladder Neoplasm BLC Urothelial Carcinoma Of The Bladder Bladder Tumors Urinary Bladder Neoplasms Bladder Cancer Nos Vesical Cancer Nos Malignant Neoplasm Of Bladder, Part Unspecified Malignant Tumour Of Urinary Bladder Primary Malignant Neoplasm Of Bladder
Gallbladder Cancer	Gallbladder Carcinoma Gallbladder Neoplasm Malignant Neoplasm Of Gallbladder Malignant Tumour Of Gallbladder Gallbladder Ca Localized Malignant Gallbladder Neoplasm Malignant Tumor Of The Gallbladder Tumor Of The Gallbladder Cancer Of The Gallbladder Carcinoma Gallbladder Carcinoma Of Gallbladder Gallbladder Neoplasms Malignant Neoplasm Of Gallbladder Localized Cancer Of Gallbladder Primary Malignant Neoplasm Of Gallbladder
Leukemia, Acute Lymphoblastic	Acute Lymphoblastic Leukemia ALL Acute Lymphocytic Leukemia Leukemia, Acute Lymphocytic, Susceptibility To, 1 Acute Lymphoblastic Leukaemia Precursor Lymphoblastic Lymphoma/Leukemia Precursor Lymphoid Neoplasm Leukemia, Acute Lymphoblastic, Susceptibility To B-Cell Acute Lymphoblastic Leukemia Leukemia, Acute Lymphocytic 1 Acute Lymphocytic Leukaemia Acute Lymphoblastic Leukemia/Lymphoma All1 Childhood Acute Lymphoblastic Leukemia Leukemia Acute Lymphoblastic 1 Leukemia Acute Lymphoblastic B-Hyperdiploid Leukemia Acute Lymphocytic Leukemia Acute Lymphocytic 1 Leukemia B-Cell Acute Lymphoblastic Leukemia T-Cell Acute Lymphoblastic Leukemia, Acute Lymphoblastic, 3 ALL3 Lymphoblastic Leukemia Acute Leukemia, Acute, Lymphoblastic Precursor Cell Lymphoblastic Leukemia Lymphoma Leukemia, Lymphocytic, Acute, L1 Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Cancer Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Lymphoma, Non-Hodgkin, Familial	Non-Hodgkin Lymphoma Lymphoma, Non-Hodgkin NHL Lymphoma, Non-Hodgkin, Somatic Lymphoma, Follicular, Somatic Familial Non-Hodgkin Lymphoma Lymphoma Non-Hodgkins Follicular Lymphoma, Somatic Lymphosarcoma Non-Hodgkins Lymphoma
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Fanconi Anemia, Complementation Group A	Fanconi Anemia Fanconi Pancytopenia Fanconi Anemia Complementation Group A FANCA Fa Fanconi Panmyelopathy Fanconi'S Anemia Fanconi Anaemia Fanconi'S Anaemia Fanconi Hypoplastic Anemia Estren-Dameshek Variant Of Fanconi Anemia Estren-Dameshek Variant Of Fanconi Pancytopenia Fanconi Anemia Estren-Dameshek Variant Fanconis Anemia
Congenital Nervous System Abnormality	Congenital Neurologic Anomaly Congenital Nervous System Disorder
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Leukemia, Myeloid, Acute Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Retinal Cancer	Malignant Neoplasm Of Retina Retinal Neoplasms Malignant Retinal Neoplasm Malignant Tumor Of Retina Neoplasm Of Retina Retinal Tumor Retinal Neoplasm Cancer Of The Retina Malignant Retinal Tumour Malignant Tumour Of Retina Primary Malignant Neoplasm Of Retina
Seckel Syndrome 4	SCKL4 Seckel Syndrome, Type 4
Ataxia-Telangiectasia	Ataxia Telangiectasia Louis-Bar Syndrome AT At1 Ataxia-Telangiectasia Syndrome Ataxia - Telangiectasia Variant Boder-Sedgwick Syndrome Louis Bar Syndrome Cerebello-Oculocutaneous Telangiectasia Immunodeficiency With Ataxia Telangiectasia A-T Ataxia Telangiectasia Syndrome Atm Telangiectasia, Cerebello-Oculocutaneous Ataxia-Telangiectasia Variant
Frontotemporal Dementia	Pallidopontonigral Degeneration Frontotemporal Lobar Degeneration Semantic Dementia FTD Frontotemporal Lobe Dementia Multiple System Tauopathy With Presenile Dementia Dementia, Frontotemporal Frontotemporal Dementia With Parkinsonism Mstd Frontotemporal Lobar Degeneration With Tau Inclusions Ftld With Tau Inclusions Dementia, Frontotemporal, With Parkinsonism Fldem Ftdp17 Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex Ddpac Wilhelmsen-Lynch Disease Wld Ppnd Dementia, Frontotemporal, With Or Without Parkinsonism Semantic Primary Progressive Aphasia Semantic Variant Ppa Wilhemsen-Lynch Disease Frontotemporal Dementia-Amyotrophic Lateral Sclerosis Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17 Ftd-Als Ftld Pick Complex Pick Disease Of The Brain Frontotemporal Dementia With Parkinsonism-17 Grn-Related Frontotemporal Dementia Frontotemporal Dementia With Motor Neuron Disease Dementia In Fronto-Temporal Lobar Degeneration Ftd - [Frontotemporal Dementia] Temple Dementia Frontal Lobe Dementia
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Protection Against Lung Cancer, Susceptibility To Adenocarcinoma Of Lung, Somatic Nonsmall Cell Lung Cancer Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Bone Cancer	Malignant Bone Neoplasm Bone Carcinoma Bone Neoplasms Bone Neoplasm Bone Tumour Ca - Bone Cancer Malignant Bone Tumour Malignant Neoplasm Of Bone Malignant Osseous Tumor Neoplasm Of Bone Osseous Tumor Osteosarcoma Of Bone Osteogenic Neoplasm
Rhabdomyosarcoma
Primary Autosomal Recessive Microcephaly	Autosomal Recessive Primary Microcephaly Mcph True Microcephaly Microcephalia Vera Microcephaly Vera Microcephaly Primary Hereditary Microcephaly, Primary, Autosomal Recessive Primary Microcephaly
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Gastric Cancer	Stomach Cancer Stomach Carcinoma Gastric Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Cataract 36	CTRCT36 Catc4 Autosomal Recessive Congenital Cataract 4 Cataract, Autosomal Recessive Congenital 4 Cataract, Type 36
Autosomal Recessive Nonsyndromic Deafness 32	Deafness, Autosomal Recessive 32 Autosomal Recessive Deafness 105 Autosomal Recessive Deafness 32 Dfnb32 Hearing Impairment Infertile Male Syndrome Hiims Deafness, Autosomal Recessive, Type 32
Cockayne Syndrome	Cockayne'S Syndrome Dwarfism-Retinal Atrophy-Deafness Syndrome Neill-Dingwall Syndrome Progeria-Like Syndrome Progeroid Nanism Cs
B-Cell Lymphoma	Lymphoma, B-Cell B-Cell Lymphomas B-Cell Lymphocytic Neoplasm Lymphoma B-Cell B-Cell Lymphoma Nos
Cornelia De Lange Syndrome	De Lange Syndrome Brachmann De Lange Syndrome Brachmann-De Lange Syndrome Cdls Bdls Typus Degenerativus Amstelodamensis
Polyploidy	Polyploid Polyploidy Syndrome
Retinoblastoma	RB Trilateral Retinoblastoma RB1 Retinoblastoma, Trilateral Neuroblastoma Of Retina Rb - Retinoblastoma Eye Cancer, Retinoblastoma Retinal Cancer Retinal Tumor Glioma, Retinal Non-Hereditary Retinoblastoma Childhood Cancer Retinoblastoma Malignant Neoplasm Of Retina Retinal Neoplasms
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (5)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-16297A	Abemaciclib	Inhibitor	99.97%	Yes
HY-10492	Dinaciclib	Inhibitor	99.80%	Yes
HY-16297	Abemaciclib methanesulfonate	Inhibitor	99.95%	Yes
HY-B0263	Thiabendazole		99.94%	Unkown
HY-B1165	Cyproheptadine (hydrochloride sesquihydrate)		99.74%	Unkown

Clinical Phase

Bioactive Molecules (35)

Referencia número	Nombre del producto	Efecto	Pureza	Phase
HY-10580	GSK 3 Inhibitor IX	Inhibitor	99.73%	Phase 4
HY-112272A	Lerociclib dihydrochloride	Inhibitor	98.51%	Phase 3
HY-112272	Lerociclib	Inhibitor	96.42%	Phase 3
HY-10005	Flavopiridol	Inhibitor	99.72%	Phase 2
HY-30237	(R)-Roscovitine	Inhibitor	99.53%	Phase 2
HY-103712A	Samuraciclib hydrochloride	Inhibitor	99.98%	Phase 2
HY-X0009	Tambiciclib	Inhibitor	99.68%	Phase 2
HY-50940	AT7519	Inhibitor	99.69%	Phase 2
HY-10006	Flavopiridol Hydrochloride	Inhibitor	99.73%	Phase 2
HY-137478	KB-0742	Inhibitor	99.63%	Phase 2
HY-137478A	KB-0742 dihydrochloride	Inhibitor	98.77%	Phase 2
HY-10424	Milciclib	Inhibitor	99.89%	Phase 2
HY-137432	Avotaciclib	Inhibitor	99.72%	Phase 2
HY-103712	Samuraciclib	Inhibitor	99.55%	Phase 2
HY-103712B	Samuraciclib hydrochloride dihydrate	Inhibitor	99.90%	Phase 2
HY-50943	AT7519 Hydrochloride	Inhibitor	99.16%	Phase 2
HY-103712C	Samuraciclib hydrochloride hydrate	Inhibitor	99.88%	Phase 2
HY-137432A	Avotaciclib trihydrochloride	Inhibitor	99.60%	Phase 2
HY-137432B	Avotaciclib hydrochloride	Inhibitor	99.75%	Phase 2
HY-50940A	AT7519 TFA	Inhibitor	99.75%	Phase 2
HY-X0009A	Tambiciclib dimaleate	Inhibitor	99.53%	Phase 2
HY-16559A	Riviciclib	Inhibitor	/	Phase 2
HY-137432D	Avotaciclib sulfate	Inhibitor	/	Phase 2
HY-10008	SNS-032	Inhibitor	99.91%	Phase 1
HY-10012	AZD-5438	Inhibitor	99.91%	Phase 1
HY-10032	PF 477736	Inhibitor	99.04%	Phase 1
HY-10014	R547	Inhibitor	99.57%	Phase 1
HY-11001	PHA-793887	Inhibitor	99.25%	Phase 1
HY-12871B	Atuveciclib	Inhibitor	99.75%	Phase 1
HY-15504	RGB-286638	Inhibitor	99.67%	Phase 1
HY-12422	Voruciclib	Inhibitor	99.76%	Phase 1
HY-15504A	RGB-286638 free base	Inhibitor	98.09%	Phase 1
HY-12422A	Voruciclib hydrochloride	Inhibitor	99.26%	Phase 1
HY-182906	XL495	Inhibitor	/	Phase 1
HY-114214	CKD-712	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (136)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-12529	Ro-3306	Inhibitor	99.83%	Unkown
HY-124719	hSMG-1 inhibitor 11j	Inhibitor	99.82%	Unkown
HY-12302	Kenpaullone	Inhibitor	98.20%	Unkown
HY-10329	JNJ-7706621	Inhibitor	99.39%	Unkown
HY-15339	CVT-313	Inhibitor	99.90%	Unkown
HY-15154	NG 52	Inhibitor	99.88%	Unkown
HY-124760	hSMG-1 inhibitor 11e	Inhibitor	99.94%	Unkown
HY-18340	(R)-CR8	Inhibitor	99.52%	Unkown
HY-122609	XO44		99.73%	Unkown
HY-18299A	Purvalanol A	Inhibitor	98.61%	Unkown
HY-15275	BMS-265246	Inhibitor	99.59%	Unkown
HY-13914	Roniciclib	Inhibitor	98.00%	Unkown
HY-108359	Alsterpaullone	Inhibitor	99.85%	Unkown
HY-15878	LDC000067	Inhibitor	99.00%	Unkown
HY-18629	SU9516	Inhibitor	99.85%	Unkown
HY-N0417	Cucurbitacin E	Inhibitor	99.92%	Unkown
HY-11009	CGP60474	Inhibitor	98.90%	Unkown
HY-13461A	PHA-767491 hydrochloride	Inhibitor	99.49%	Unkown
HY-12445	Asnuciclib	Inhibitor	99.76%	Unkown
HY-117535	CDK2-IN-4	Inhibitor	99.85%	Unkown
HY-X0150	JSH-150	Inhibitor	98.36%	Unkown
HY-15569	NU6102	Inhibitor	99.23%	Unkown
HY-103221	MeBIO	Inhibitor	98.0%	Unkown
HY-18340A	(R)-CR8 trihydrochloride	Inhibitor	99.37%	Unkown
HY-13461	PHA-767491	Inhibitor	99.97%	Unkown
HY-18299	Purvalanol B	Inhibitor	97.0%	Unkown
HY-N2424	Flavone	Inhibitor	99.85%	Unkown
HY-12280	THZ2	Inhibitor	99.03%	Unkown
HY-16559	Riviciclib hydrochloride		99.08%	Unkown
HY-175842	CDK2 degrader 7	Degrader	99.51%	Unkown
HY-13266A	BS-181 hydrochloride	Inhibitor	99.93%	Unkown
HY-119940	MC180295	Inhibitor	98.07%	Unkown
HY-103647	K00546	Inhibitor	99.48%	Unkown
HY-129478	TC11	Activator	99.55%	Unkown
HY-162919	YK-2168	Inhibitor	98.05%	Unkown
HY-151071	TMX-3013	Inhibitor	98.02%	Unkown
HY-50914	AZD5597	Inhibitor	98.09%	Unkown
HY-N5072	Desmethylglycitein	Inhibitor	99.99%	Unkown
HY-15889	AMG 925	Inhibitor	99.02%	Unkown
HY-112403	(S)-Roscovitine	Inhibitor	99.15%	Unkown
HY-115924	CDK1-IN-1	Inhibitor	99.33%	Unkown
HY-111237	Butyrolactone I	Inhibitor	99.80%	Unkown
HY-115565	CGP-74514	Inhibitor	98.02%	Unkown
HY-151069	TMX-2039	Inhibitor	99.42%	Unkown
HY-13816	NU6027	Inhibitor	98.01%	Unkown
HY-139980	CDK9-IN-13	Inhibitor	99.94%	Unkown
HY-107419	NU6140	Inhibitor	99.53%	Unkown
HY-112462	Cdk1/2 Inhibitor III	Inhibitor	99.69%	Unkown
HY-14372	BS-194	Inhibitor	99.13%	Unkown
HY-148062	RSS0680		99.85%	Unkown
HY-123045	PNU-292137	Inhibitor	99.95%	Unkown
HY-100429	CAN508	Inhibitor	99.71%	Unkown
HY-15241	NVP-LCQ195	Inhibitor	98.88%	Unkown
HY-112463	CDK1-IN-2	Inhibitor	98.89%	Unkown
HY-111930	5-Iodo-indirubin-3'-monoxime	Inhibitor	98.12%	Unkown
HY-136726	CGP-82996	Inhibitor	98.12%	Unkown
HY-119715	AG-012986	Inhibitor	99.78%	Unkown
HY-155787	SHR5428	Inhibitor	99.80%	Unkown
HY-19316	NU2058	Inhibitor	99.66%	Unkown
HY-168673	CDK1-IN-6	Inhibitor	99.96%	Unkown
HY-13266	BS-181	Inhibitor	98.10%	Unkown
HY-147646	CDK1/Cyc B-IN-1	Inhibitor	98.47%	Unkown
HY-114903	(E/Z)-BIO-acetoxime	Inhibitor	99.9%	Unkown
HY-103381	NSC693868	Inhibitor	99.0%	Unkown
HY-103383	(R)-DRF053 dihydrochloride	Inhibitor	99.30%	Unkown
HY-112346	RGB-286147	Inhibitor	98.60%	Unkown
HY-178227	KY19334	Inhibitor	99.78%	Unkown
HY-121989	cis-Trismethoxy resveratrol	Inhibitor	99.87%	Unkown
HY-142696	CDK6/PIM1-IN-1	Inhibitor	/	Unkown
HY-164906	TMX-2138	Degrader	98.99%	Unkown
HY-153556	GW297361	Inhibitor	98.13%	Unkown
HY-180485	PROTAC D16-M1P2		/	Unkown
HY-15889A	AMG 925 (HCl)	Inhibitor	/	Unkown
HY-N12625	(R)-(+)-O-Demethylbuchenavianine	Inhibitor	98.67%	Unkown
HY-112450	Olomoucine II	Inhibitor	98.0%	Unkown
HY-151409	CDK1-IN-5	Inhibitor	/	Unkown
HY-151407	CDK1-IN-3	Inhibitor	/	Unkown
HY-126244	CDK4/6-IN-3	Inhibitor	/	Unkown
HY-181140	UNPD139734	Inhibitor	/	Unkown
HY-182986	LS-Q2	Inhibitor	/	Unkown
HY-179012	CDC20/HSP90-IN-1	Inhibitor	/	Unkown
HY-179614	PARP1-IN-50	Inhibitor	/	Unkown
HY-181978	GIT1-IN-1	Inhibitor	/	Unkown
HY-141685	3-Methylthienyl-carbonyl-JNJ-7706621	Inhibitor	/	Unkown
HY-123034	CDKI-83	Inhibitor	/	Unkown
HY-180484	PKMYT1-IN-12	Inhibitor	/	Unkown
HY-151408	CDK1-IN-4	Inhibitor	/	Unkown
HY-163856	CDK7-IN-30	Inhibitor	/	Unkown
HY-146276	CDK/HDAC-IN-2	Inhibitor	/	Unkown
HY-161826	Antitumor agent-174	Inhibitor	/	Unkown
HY-184444	CDK4-IN-7	Inhibitor	/	Unkown
HY-151898	CDK4/6-IN-14	Inhibitor	/	Unkown
HY-123369	BMI-1026	Inhibitor	/	Unkown
HY-173348	BLINK15	Inhibitor	/	Unkown
HY-182470	AG-012986 dihydrochloride	Inhibitor	/	Unkown
HY-146253	CDK1/2/4-IN-1	Inhibitor	/	Unkown
HY-112471	TrkA Inhibitor	Inhibitor	/	Unkown
HY-183787	PI3Kα-IN-33	Inhibitor	/	Unkown
HY-178756	CDK2-IN-48	Inhibitor	/	Unkown
HY-179023	CDK9-IN-45	Inhibitor	/	Unkown
HY-181004	PKMYT1-IN-13	Inhibitor	/	Unkown
HY-177780	Cyclin K degrader 2	Degrader	/	Unkown
HY-183547	WEE1/PKMYT1-IN-4	Inhibitor	/	Unkown
HY-110359	CGP-74514 dihydrochloride	Inhibitor	/	Unkown
HY-181098	FKA-9i	Inhibitor	/	Unkown
HY-182734	BMS-357075	Inhibitor	/	Unkown
HY-P11028	M1-20	Inhibitor	/	Unkown
HY-182752	CDK1-IN-9	Inhibitor	/	Unkown
HY-137478B	KB-0742 hydrochloride	Inhibitor	/	Unkown
HY-179052	Apoptosis inducer 50	Inhibitor	/	Unkown
HY-173347	BLINK11	Inhibitor	/	Unkown
HY-111932	Indirubin-5-sulfonate	Inhibitor	/	Unkown
HY-179521	CDK1-IN-8	Inhibitor	/	Unkown
HY-181763	Tubulin-IN-65	Activator	/	Unkown
HY-170306	LZ9	Inhibitor	/	Unkown
HY-147901	KDM1/CDK1-IN-1	Inhibitor	/	Unkown
HY-115942	Anticancer agent 29	Inhibitor	/	Unkown
HY-112363	Aloisine A	Inhibitor	/	Unkown
HY-112336	Aloisine RP106	Inhibitor	/	Unkown
HY-118976	CGP-74514 hydrochloride	Inhibitor	/	Unkown
HY-167237	Calactin	Inhibitor	/	Unkown
HY-180817	CDK2-IN-55	Inhibitor	98.91%	Unkown
HY-181838	CIRc-014	Inhibitor	/	Unkown
HY-111931	Indirubin-3'-monoxime-5-sulphonic acid	Inhibitor	/	Unkown
HY-178112	CDK2-IN-47	Inhibitor	/	Unkown
HY-180912	HS-36	Inhibitor	/	Unkown
HY-170651	CDK4/6/HDAC-IN-1	Inhibitor	/	Unkown
HY-151878	CDK7-IN-20	Inhibitor	/	Unkown
HY-180820	Dimethyl bisphenolate	Inhibitor	/	Unkown
HY-170965	Anticancer agent 264	Inhibitor	/	Unkown
HY-183854	AG-12286	Inhibitor	/	Unkown
HY-11001A	PHA-793887 hydrochloride	Inhibitor	/	Unkown
HY-112394	2-Cyanoethylalsterpaullone	Inhibitor	/	Unkown
HY-181030	BDE30671203	Inhibitor	/	Unkown
HY-19926A	GDC-0425 hydrochloride	Inhibitor	/	Unkown
HY-160643	CDK2-IN-27	Inhibitor	/	Unkown

Inhibitory Antibodies (1)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-P991218	Anti-IL11 Antibody (X203)	Modulator	98.53%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CDK1	MGD	MGI:88351
Rattus norvegicus	CDK1	RGD	RGD:2319
Felis catus	CDK1	VGNC	VGNC:97378
Canis familiaris	CDK1	VGNC	VGNC:39042
Bos taurus	CDK1	VGNC	VGNC:27115
Macaca mulatta	CDK1	VGNC	VGNC:100309
Others	CDK1	NCBI