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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
(E/Z)-ABP/PPAR modulator 1
" in MedChemExpress (MCE) Product Catalog:
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1 Results for "(E/Z)-ABP/PPAR modulator 1" in MCE Product Catalog:
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Pathways
Recommended:
- GPCR/G Protein
- Stem Cell/Wnt
- Cytoskeleton
- Apoptosis
- Metabolic Enzyme/Protease
- Neuronal Signaling
- NF-κB
- Epigenetics
- JAK/STAT Signaling
- TGF-beta/Smad
- Protein Tyrosine Kinase/RTK
- Antibody-Drug Conjugate/ADC Related
- PROTAC
- Vitamin D Related/Nuclear Receptor
- Anti-infection
- Immunology/Inflammation
- Cell Cycle/DNA Damage
- Autophagy
- Others
- MAPK/ERK Pathway
- Membrane Transporter/Ion Channel
- PI3K/Akt/mTOR
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Isoforms
Recommended:
- iNOS
- CYP4
- PRMT7
- apoA4
- CXCR1
- PKD3
- GPX4
- PDE12
- CES1
- V1b Receptor
- LPAR6
- NEK1
- GFRα4
- FFAR4
- 3β-HSD III
- D2 Receptor
- Protein Polybromo-1
- MRCKα
- EHD3
- PTH3R
- HCAR1
- TRPV1
- DCAF11
- PRMT3
- TNFRSF3/CD18
- SHMT2
- SGLT1
- PGK1
- NOX2
- PRKY
- RUNX2
- EHMT1/GLP/KMT1D
- CA XII
- TRPM4
- JNK1
- JNK2
- JNK3
- PI3Kα
- PI3Kβ
- PI3Kδ
- CDK1
- CDK2
- CDK3
- CDK4
- CDK5
- CDK6
- CDK7
- CDK8
- CDK9
- CDK11
- CDK12
- CDK13
- EGFR/ErbB1/HER1
- ErbB2/HER2
- ErbB3/HER3
- ErbB4/HER4
- VEGFR1/Flt-1
- VEGFR2/KDR/Flk-1
- VEGFR3/Flt-4
- HDAC1
- HDAC2
- HDAC3
- HDAC4
- HDAC5
- HDAC6
- HDAC7
- HDAC8
- HDAC9
- HDAC10
- HDAC11
- Akt2
- Akt3
- ROCK1
- ROCK2
- PDGFRβ
- B-Raf
- CDC
- CDK19
- JAK2
- GSK-3β
- Aurora A
- Aurora B
- GSK-3α
- TrkB
- TrkC
- ERK1
- ERK2
- CLK
- PDGFRα
- PI3Kγ
- Vps34
- ATM
- ATR
- BRD4
- MEK1
- N-type calcium channel
- PI3KC2β
- PI4KIIIβ
- PI4KIIIα
- PI3KC2α
- mTORC1
- mTORC2
- JAK3
- C-Raf
- TrkA
- HD1
- HD2
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- SIRT2
- SIRT3
- Chk1
- Chk2
- Aurora C
- MEK2
- JAK1
- IDO
- IDO1
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- NUAK2
- AMPK α1β1γ1
- AMPK α2β1γ1
- AMPK α1β2γ1
- AMPK α2β2γ1
- MMP-9
- PPARα
- PLK1
- PLK2
- PLK3
- PLK4
- PLK5
- RelB
- c-Rel
- IKK-β
- IKK-α
- IKKε
- TBK1
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- TNKS1/PARP5A
- TNKS2/PARP5B
- EP
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- ACAT1
- ACAT2
- MGAT2
- PDE2
- PDE10
- PDE11
- PDE4
- CBP/p300
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- MAP4K6/MINK1
- RGS4
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- RGS8
- Abl
- PPARγ
- L-type calcium channel
- LIMK1
- LIMK2
- HIV-1
- HIV-2
- Topo I
- Topo II
- PARP1
- HSV-1
- HSV-2
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Targets
Recommended:
- PPAR
- ROCK
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- Asialoglycoprotein Receptor (ASGPR)
- EGFR
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- Proton Pump
- Oxytocin Receptor
- IFNAR
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- SLK
- Prion Protein
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- Akt
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- PARP
- Penicillin-binding protein (PBP)
- Glycosidase
- Disulfidptosis
- Chloride Channel
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- Discoidin Domain Receptor
- Itk
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- FLT3
- Tissue Factor Pathway Inhibitor (TFPI)
- KLF
- Mitogen- and Stress-Activated Protein Kinase (MSK)
- Indoleamine 2,3-Dioxygenase (IDO)
- Others
- CFTR
- Pyroptosis
- Actin
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- Myosin
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- 5-HT Receptor
- Tim3
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- Apical Sodium-Dependent Bile Acid Transporter
- Integrin
- Xanthine Oxidase
- PKD
- Wnt
- Androgen Receptor
- Connective Peptide
- IKZF Family
- L-Selectin
- Autophagy
- Claudin
- Drug Isomer
- Bradykinin Receptor
- TSH Receptor
- OLIG2
- PDI
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- Photosensitizer
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- Angiotensin-converting Enzyme (ACE)
- URAT1
- Orthopoxvirus
- ABA Receptor
- SHP1
- Smo
- Arp2/3 Complex
- ALCAM/CD166
- Urea Transporter
- Raf
- Arenavirus
- PDK-1
- COMT
- Orphan GPCR
- Lysyl Oxidase
- PCSK9
- REV-ERB
- Glucocorticoid Receptor
- YTHDF
- Biochemical Assay Reagents
- HIV Integrase
- Keap1-Nrf2
- Kisspeptin Receptor
- Phosphorylase
- PEPCK
- CGRP Receptor
- RUNX
- DNA Stain
- PGE synthase
- MicroRNA
- Acetyl-CoA Carboxylase
- Lactate Dehydrogenase
- G-quadruplex
- Prokineticin Receptor
- ICMT
- Neuropeptide Y Receptor
- Interleukin Related
- mTOR
- SLC39 (Zinc Transporter)
- Cadherin
- Influenza Virus
- RAR/RXR
- BCL6
- Transferrin Receptor
- Protease Activated Receptor (PAR)
- Succinate Receptor 1
- Secretin Receptor
- ASCT
- Synaptic Vesicle Proteins
- NF-κB
- Reference Standards
- S-adenosylhomocysteine hydrolase (SAHH)
- GPR55
- Heme Oxygenase (HO)
- RIBOTAC
- Acetyl-CoA synthetase
- Drug Derivative
- Dengue Virus
- Bombesin Receptor
- RNA MTase
- ATTECs
- Fatty Acid Synthase (FASN)
- Oct3/4
- GPR88
- PI5P4K
- IRE1
- Nuclear Hormone Receptor 4A/NR4A
- p38 MAPK
- MCHR1 (GPR24)
- Dihydroceramide Desaturase 1 (DES1)
- Calcium Channel
- Transthyretin (TTR)
- GLUT
- N-myristoyltransferase
- Dihydroorotate Dehydrogenase
- Ligands for Target Protein for PROTAC
- GPR171
- ATGL
- DNA/RNA Synthesis
- Serine Racemase (SR)
- PI4K
- Human leukocyte immunoglobulin (Ig)-like receptors (LILR)
- DNA-PK
- mAChR
- MARCKS
- C-type Lectin-like Receptors (CTLRs)
- Reactive Oxygen Species (ROS)
- ATF6
- Enolase
- HCN Channel
- CD3
- Monocarboxylate Transporter
- Measles Virus
- IGF-1R
- ATP Citrate Lyase
- Beta-secretase
- Dystrophin
- Carboxypeptidase
- VD/VDR
- LILRB
- Ferroportin
- Thymidylate Synthase
- Pim
- IPK Superfamily
- Survivin
- Amine N-methyltransferase
- Separase
- Eukaryotic Release Factor (eRF)
- IDE
- Factor Xa
- Pyruvate Kinase
- Dopamine Transporter
- NADPH Oxidase
- PROTAC-Linker Conjugates for PAC
- PROTAC Linkers
- P2Y Receptor
- Hormone-Sensitive Lipase (HSL)
- Galectin
- Angiotensin Receptor
- Isocitrate Dehydrogenase (IDH)
- β-glucuronidase
- CD1
- CDK
- HRASLS
- Microsomal Triglyceride Transfer Protein (MTP)
- Microtubule/Tubulin
- Deubiquitinase
- GPR35
- Glycine Receptor (GlyR)
- Transcription Factor ERG
- TREM receptor
- SRPK
- Ser/Thr Protease
- HDAC
- MELK
- PIKfyve
- STING
- GnRH Receptor
- GPR119
- Tyrosinase
- Scavenger Receptor Class B type I (SR-BI）
- NEDD8-activating Enzyme
- Hedgehog
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- Pyruvate Carboxylase (PC)
- Methylenetetrahydrofolate Dehydrogenase (MTHFD)
- Polo-like Kinase (PLK)
- Beclin1
- SphK
- Arginase
- α-synuclein
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- Nectin-4
- Arrestin
- ACSL Family
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- Acyltransferase
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- Somatostatin Receptor
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- Orphan Receptor
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- Steroid Sulfatase
- Glutathione S-transferase
- Adenosine Kinase
- HSP
- VEGFR
- CRAC Channel
- Dipeptidyl Peptidase
- TMV
- IMPDH
- Mixed Lineage Kinase
- ClpP
- 3β-HSD
- SHMT
- GSK-3
- MetAP
- GHR
- Radionuclide-Drug Conjugates (RDCs)
- Prostaglandin Receptor
- Urotensin Receptor
- ADAMTS
- Dihydropyrimidine Dehydrogenase (DPD)
- CD38
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- PKC
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- GPR39
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- STAT
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- EHD Protein
- γ-secretase
- Kinesin
- Ninjurin
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- RAD51
- Neprilysin
- Histamine Receptor
- MHC
- KMO
- Nuclear Factor of activated T Cells (NFAT)
- c-Met/HGFR
- Aquaporin
- Sodium Channel
- Serpin
- MyD88
- FOXM1
- Potassium Channel
- Mps1
- Hexokinase
- Na+/K+ ATPase
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- TGF-beta/Smad
- Amyloid-β
- Histone Methyltransferase
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- UGT
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- Cdc42-binding kinase
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- Molecular Glues
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- ERK
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- Glucose-6-Phosphate Isomerase (GPI)
- Cytochrome P450
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- Cannabinoid Receptor
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- LRRK2
- Pirin
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- c-Myc
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- Protein Prenyltransferase
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- 11β-HSD
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- Beta-lactamase
- Na+/Ca2+ Exchanger
- Reverse Transcriptase
- ATP Synthase
- Aminopeptidase
- AMPK
- APC
- SOS1
- FOXJ
- SARS-CoV
- Peptides Recommended:
Cat. No.: HY-172883A
Research Areas:
(E/Z)-ABP/PPAR modulator 1 is a mixture of the E and Z isomers of ABP/PPAR modulator 1 (HY-172883). ABP/PPAR modulator 1 is an orally active FABP and PPAR multiple modulator (IC50s of 0.65 μM and 1.08 μM for FABP1 and FABP4, EC50 s of 9.19 μM, 2.20 μM and 1.58 μM for PPARα, PPARγ and PPARδ). ABP/PPAR modulator 1 has potent anti-metabolic dysfunction-associated steatohepatitis (MASH) activity. ABP/PPAR modulator 1 dose-dependently ameliorates multiple pathological characteristics of fatty liver in WD + Carbon tetrachloride-induced MASH mice model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
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| Quantity: |
Assay Types