5'-dCMP

By Targets:	Apoptosis (2) DNA/RNA Synthesis (3) Drug Derivative (1) Drug Metabolite (2) Endogenous Metabolite (7) Isotope-Labeled Compounds (4) PKC (1) Reference Standards (1)
By Research Areas:	Cancer (2) Infection (1) Metabolic Disease (6)
Oligonucleotides:	Nucleoside Analogs (2) Cytidine (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17026E

Gemcitabine triphosphate trisodium dFdCTP trisodium	Drug Metabolite DNA/RNA Synthesis Apoptosis	Cancer
Gemcitabine triphosphate (dFdCTP) trisodium is the active metabolite of Gemcitabine (HY-17026). The mechanism of Gemcitabine triphosphate trisodium cell-killing is its competition with cytidine triphosphate during DNA replication, which results in the inhibition of chain elongation. Gemcitabine triphosphate trisodium shows a K_i of 11.2 μM against DNA polymerase α and 14.4 μM against DNA polymerase ε. Gemcitabine triphosphate trisodium partially inhibits dCMP deaminase and acts as a substrate for DNA synthesis to incorporate into cellular DNA and RNA. Gemcitabine triphosphate trisodium disrupts DNA and RNA synthesis, arrests cell cycle in G0/G1 and S phases, triggers apoptosis, reduces tumor cell proliferation. Gemcitabine triphosphate trisodium can be used for the research of pancreatic cancer and non-small cell lung cancer .

HY-17026A

Gemcitabine triphosphate dFdCTP	Drug Metabolite DNA/RNA Synthesis Apoptosis	Cancer
Gemcitabine triphosphate (dFdCTP) is the active metabolite of Gemcitabine (HY-17026). The mechanism of Gemcitabine triphosphate cell-killing is its competition with cytidine triphosphate during DNA replication, which results in the inhibition of chain elongation. Gemcitabine triphosphate shows a K_i of 11.2 μM against DNA polymerase α and 14.4 μM against DNA polymerase ε. Gemcitabine triphosphate partially inhibits dCMP deaminase and acts as a substrate for DNA synthesis to incorporate into cellular DNA and RNA. Gemcitabine triphosphate disrupts DNA and RNA synthesis, arrests cell cycle in G0/G1 and S phases, triggers apoptosis, reduces tumor cell proliferation. Gemcitabine triphosphate can be used for the research of pancreatic cancer and non-small cell lung cancer .

HY-W009216

2'-Deoxycytidine-5'-monophosphate 1 Publications Verification 5'-dCMP; Deoxy-CMP; 2'-Deoxycytidine-5'-monophosphoric acid	DNA/RNA Synthesis	Infection
2'-Deoxycytidine-5'-monophosphate (5'-dCMP) is a compound that binds to the adenovirus terminal protein with a molecular weight of 80000 daltons. 2'-Deoxycytidine-5'-monophosphate forms a covalent complex with this protein and is associated with adenovirus DNA replication .

HY-W011152

2'-Deoxycytidine-5'-monophosphoric acid disodium 1 Publications Verification dCMP disodium	Endogenous Metabolite	Others
2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) is an endogenous metabolite .

HY-W009216R

2'-Deoxycytidine-5'-monophosphate (Standard) 5'-dCMP (Standard); Deoxy-CMP (Standard); 2'-Deoxycytidine-5'-monophosphoric acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
2'-Deoxycytidine-5'-monophosphoric acid (Standard) is the analytical standard of 2'-Deoxycytidine-5'-monophosphoric acid. This product is intended for research and analytical applications. 2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite. 2'-Deoxycytidine-5'-monophosphate is a deoxynucleotide building block of which DNA is made. 2'-Deoxycytidine-5'-monophosphate can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP and supports DNA biosynthesis .

HY-W009216S

2'-Deoxycytidine-5'-monophosphate-15N3 5'-dCMP-¹⁵N₃; Deoxy-CMP-¹⁵N₃; 2'-Deoxycytidine-5'-monophosphoric acid-¹⁵N₃	Endogenous Metabolite	Metabolic Disease
2'-Deoxycytidine-5'-monophosphoric acid- ¹⁵N₃ is the ¹⁵N labeled 2'-Deoxycytidine-5'-monophosphoric acid . 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.

HY-W009216S4

2'-Deoxycytidine-5'-monophosphate-13C9 dilithium 5'-dCMP-13C9 dilithium; Deoxy-CMP-13C9 dilithium; 2'-Deoxycytidine-5'-monophosphoric acid-13C9 dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
2'-Deoxycytidine-5'-monophosphoric acid- ¹³C₉ dilithium is the ¹³C-labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite .

HY-131813

5'-dCMPS 2'-Deoxycytidine-5'-O-monophosphorothioate	Drug Derivative	Others
5'-dCMPS is an analogue of 5'-dCMP and a potential substrate, competitive inhibitor or regulator of enzymes that interact with 5'-dCMP .

HY-E70108

Cytidylate kinase	PKC	Others
Cytidylate kinase catalyzes the phosphoryl transfer from ATP to CMP and dCMP, resulting in the formation nucleoside diphosphates .

HY-W009216S3

2'-Deoxycytidine-5'-monophosphate-d12 dilithium 5'-dCMP-d12 dilithium; Deoxy-CMP-d12 dilithium; 2'-Deoxycytidine-5'-monophosphoric acid-d12 dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
2'-Deoxycytidine-5'-monophosphoric acid-d₁₂ dilithium is deuterium labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.

HY-W009216S2

2'-Deoxycytidine-5'-monophosphate-15N3,d12 dilithium 5'-dCMP-15N3,d12 dilithium; Deoxy-CMP-15N3,d12 dilithium; 2'-Deoxycytidine-5'-monophosphoric acid-15N3,d12 dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
2'-Deoxycytidine-5'-monophosphoric acid- ¹⁵N₃,d₁₂ dilithium is deuterium and ¹⁵N labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.

HY-W009216S1

2'-Deoxycytidine-5'-monophosphate-13C9,15N3 dilithium 5'-dCMP-13C9,15N3 dilithium; Deoxy-CMP-13C9,15N3 dilithium; 2'-Deoxycytidine-5'-monophosphoric acid-13C9,15N3 dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
2'-Deoxycytidine-5'-monophosphoric acid- ¹³C₉, ¹⁵N₃ dilithium is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.

Cat. No.	Product Name	Type

HY-W011152

2'-Deoxycytidine-5'-monophosphoric acid disodium 1 Publications Verification dCMP disodium	Biochemical Assay Reagents
2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) is an endogenous metabolite .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-17026E

Gemcitabine triphosphate trisodium dFdCTP trisodium	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Drug Metabolite DNA/RNA Synthesis Apoptosis
Gemcitabine triphosphate (dFdCTP) trisodium is the active metabolite of Gemcitabine (HY-17026). The mechanism of Gemcitabine triphosphate trisodium cell-killing is its competition with cytidine triphosphate during DNA replication, which results in the inhibition of chain elongation. Gemcitabine triphosphate trisodium shows a K_i of 11.2 μM against DNA polymerase α and 14.4 μM against DNA polymerase ε. Gemcitabine triphosphate trisodium partially inhibits dCMP deaminase and acts as a substrate for DNA synthesis to incorporate into cellular DNA and RNA. Gemcitabine triphosphate trisodium disrupts DNA and RNA synthesis, arrests cell cycle in G0/G1 and S phases, triggers apoptosis, reduces tumor cell proliferation. Gemcitabine triphosphate trisodium can be used for the research of pancreatic cancer and non-small cell lung cancer .

HY-17026A

Gemcitabine triphosphate dFdCTP	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Drug Metabolite DNA/RNA Synthesis Apoptosis
Gemcitabine triphosphate (dFdCTP) is the active metabolite of Gemcitabine (HY-17026). The mechanism of Gemcitabine triphosphate cell-killing is its competition with cytidine triphosphate during DNA replication, which results in the inhibition of chain elongation. Gemcitabine triphosphate shows a K_i of 11.2 μM against DNA polymerase α and 14.4 μM against DNA polymerase ε. Gemcitabine triphosphate partially inhibits dCMP deaminase and acts as a substrate for DNA synthesis to incorporate into cellular DNA and RNA. Gemcitabine triphosphate disrupts DNA and RNA synthesis, arrests cell cycle in G0/G1 and S phases, triggers apoptosis, reduces tumor cell proliferation. Gemcitabine triphosphate can be used for the research of pancreatic cancer and non-small cell lung cancer .

HY-W009216R

2'-Deoxycytidine-5'-monophosphate (Standard) 5'-dCMP (Standard); Deoxy-CMP (Standard); 2'-Deoxycytidine-5'-monophosphoric acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite	Reference Standards Endogenous Metabolite
2'-Deoxycytidine-5'-monophosphoric acid (Standard) is the analytical standard of 2'-Deoxycytidine-5'-monophosphoric acid. This product is intended for research and analytical applications. 2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite. 2'-Deoxycytidine-5'-monophosphate is a deoxynucleotide building block of which DNA is made. 2'-Deoxycytidine-5'-monophosphate can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP and supports DNA biosynthesis .

Cat. No.	Product Name	Chemical Structure

HY-W009216S

2'-Deoxycytidine-5'-monophosphate-15N3
2'-Deoxycytidine-5'-monophosphoric acid- ¹⁵N₃ is the ¹⁵N labeled 2'-Deoxycytidine-5'-monophosphoric acid . 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.

HY-W009216S4

2'-Deoxycytidine-5'-monophosphate-13C9 dilithium
2'-Deoxycytidine-5'-monophosphoric acid- ¹³C₉ dilithium is the ¹³C-labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite .

HY-W009216S3

2'-Deoxycytidine-5'-monophosphate-d12 dilithium
2'-Deoxycytidine-5'-monophosphoric acid-d₁₂ dilithium is deuterium labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.

HY-W009216S2

2'-Deoxycytidine-5'-monophosphate-15N3,d12 dilithium
2'-Deoxycytidine-5'-monophosphoric acid- ¹⁵N₃,d₁₂ dilithium is deuterium and ¹⁵N labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.

HY-W009216S1

2'-Deoxycytidine-5'-monophosphate-13C9,15N3 dilithium
2'-Deoxycytidine-5'-monophosphoric acid- ¹³C₉, ¹⁵N₃ dilithium is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.

Cat. No.	Product Name		Classification

HY-W009216

2'-Deoxycytidine-5'-monophosphate 1 Publications Verification 5'-dCMP; Deoxy-CMP; 2'-Deoxycytidine-5'-monophosphoric acid		Nucleoside Analogs Cytidine
2'-Deoxycytidine-5'-monophosphate (5'-dCMP) is a compound that binds to the adenovirus terminal protein with a molecular weight of 80000 daltons. 2'-Deoxycytidine-5'-monophosphate forms a covalent complex with this protein and is associated with adenovirus DNA replication .

HY-W011152

2'-Deoxycytidine-5'-monophosphoric acid disodium 1 Publications Verification dCMP disodium		Nucleoside Analogs Cytidine
2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) is an endogenous metabolite .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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