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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
2',4'-DHC
" in MedChemExpress (MCE) Product Catalog:
Products (3)
Resources (0)
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3 Results for "2',4'-DHC" in MCE Product Catalog:
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Relevance
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Most Publications
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Pathways
Recommended:
- GPCR/G Protein
- Stem Cell/Wnt
- Cytoskeleton
- Apoptosis
- Metabolic Enzyme/Protease
- Neuronal Signaling
- NF-κB
- Epigenetics
- JAK/STAT Signaling
- TGF-beta/Smad
- Protein Tyrosine Kinase/RTK
- Antibody-Drug Conjugate/ADC Related
- PROTAC
- Vitamin D Related/Nuclear Receptor
- Anti-infection
- Immunology/Inflammation
- Cell Cycle/DNA Damage
- Autophagy
- Others
- MAPK/ERK Pathway
- Membrane Transporter/Ion Channel
- PI3K/Akt/mTOR
-
Isoforms
Recommended:
- iNOS
- CYP4
- PRMT7
- apoA4
- CXCR1
- PKD3
- GPX4
- PDE12
- CES1
- V1b Receptor
- LPAR6
- NEK1
- GFRα4
- FFAR4
- 3β-HSD III
- D2 Receptor
- Protein Polybromo-1
- MRCKα
- EHD3
- PTH3R
- HCAR1
- TRPV1
- DCAF11
- PRMT3
- TNFRSF3/CD18
- SHMT2
- SGLT1
- PGK1
- NOX2
- PRKY
- RUNX2
- EHMT1/GLP/KMT1D
- CA XII
- TRPM4
- JNK1
- JNK2
- JNK3
- PI3Kα
- PI3Kβ
- PI3Kδ
- CDK1
- CDK2
- CDK3
- CDK4
- CDK5
- CDK6
- CDK7
- CDK8
- CDK9
- CDK11
- CDK12
- CDK13
- EGFR/ErbB1/HER1
- ErbB2/HER2
- ErbB3/HER3
- ErbB4/HER4
- VEGFR1/Flt-1
- VEGFR2/KDR/Flk-1
- VEGFR3/Flt-4
- HDAC1
- HDAC2
- HDAC3
- HDAC4
- HDAC5
- HDAC6
- HDAC7
- HDAC8
- HDAC9
- HDAC10
- HDAC11
- Akt2
- Akt3
- ROCK1
- ROCK2
- PDGFRβ
- B-Raf
- CDC
- CDK19
- JAK2
- GSK-3β
- Aurora A
- Aurora B
- GSK-3α
- TrkB
- TrkC
- ERK1
- ERK2
- CLK
- PDGFRα
- PI3Kγ
- Vps34
- ATM
- ATR
- BRD4
- MEK1
- N-type calcium channel
- PI3KC2β
- PI4KIIIβ
- PI4KIIIα
- PI3KC2α
- mTORC1
- mTORC2
- JAK3
- C-Raf
- TrkA
- HD1
- HD2
- SIRT1
- SIRT2
- SIRT3
- Chk1
- Chk2
- Aurora C
- MEK2
- JAK1
- IDO
- IDO1
- NUAK1
- NUAK2
- AMPK α1β1γ1
- AMPK α2β1γ1
- AMPK α1β2γ1
- AMPK α2β2γ1
- MMP-9
- PPARα
- PLK1
- PLK2
- PLK3
- PLK4
- PLK5
- RelB
- c-Rel
- IKK-β
- IKK-α
- IKKε
- TBK1
- MAP3K7/TAK1
- TNKS1/PARP5A
- TNKS2/PARP5B
- EP
- TXA2/TP
- ACAT1
- ACAT2
- MGAT2
- PDE2
- PDE10
- PDE11
- PDE4
- CBP/p300
- TIP60
- MAP4K4/HGK
- MAP4K5/KHS1
- MAP4K6/MINK1
- RGS4
- RGS19
- RGS16
- RGS8
- Abl
- PPARγ
- L-type calcium channel
- LIMK1
- LIMK2
- HIV-1
- HIV-2
- Topo I
- Topo II
- PARP1
- HSV-1
- HSV-2
- TXB2
-
Targets
Recommended:
- ROCK
- Phosphodiesterase (PDE)
- Asialoglycoprotein Receptor (ASGPR)
- EGFR
- Kallikrein
- Proton Pump
- Oxytocin Receptor
- IFNAR
- Endonuclease
- GPR109A
- Parasite
- Prolyl Endopeptidase (PREP)
- Amino Acid Derivatives
- BTB/POZ Family
- Oxysterol-binding Protein-related Protein (ORP)
- SOD
- YAP
- OAT
- Drug Metabolite
- Epigenetic Reader Domain
- FOXO
- Fluorescent Dye
- Gli
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- PAI-1
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- NEKs
- p62
- Ceramidase
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- FABP
- Elastase
- MEK
- Amino Acid Decarboxylase
- VAP-1
- RIO Kinase
- GLP Receptor
- Pyk2
- Complement System
- Macrophage migration inhibitory factor (MIF)
- hnRNP
- Emopamil Binding Protein
- Ferrochelatase
- Dan family
- Dopamine Receptor
- LAG-3
- AP-1
- Carnitine Palmitoyltransferase (CPT)
- SLK
- Prion Protein
- SF3B1
- MAPKAPK2 (MK2)
- CXCR
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- Ligands for E3 Ligase
- PERK
- JAK
- CD276/B7-H3
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- Topoisomerase
- Adenylate Cyclase
- FLAP
- Akt
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- Tryptophan Hydroxylase
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- CD22
- Telomerase
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- FAP
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- RXFP Receptor
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- Microphthalmia Associated Transcription Factor (MITF)
- PARP
- Penicillin-binding protein (PBP)
- Glycosidase
- Disulfidptosis
- Chloride Channel
- Free Radical Scavengers
- Discoidin Domain Receptor
- Itk
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- FLT3
- Tissue Factor Pathway Inhibitor (TFPI)
- KLF
- Mitogen- and Stress-Activated Protein Kinase (MSK)
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- Others
- CFTR
- Pyroptosis
- Actin
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- Urease
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- PI4P5K
- Myosin
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- 5-HT Receptor
- Tim3
- Glutamate Dehydrogenase (GLDH)
- Programmed Cell Death 4 (PDCD4)
- Apical Sodium-Dependent Bile Acid Transporter
- Integrin
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- PKD
- Wnt
- Androgen Receptor
- Connective Peptide
- IKZF Family
- L-Selectin
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- Claudin
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- Bradykinin Receptor
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- OLIG2
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- Photosensitizer
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- URAT1
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- Smo
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- ALCAM/CD166
- Urea Transporter
- Raf
- Arenavirus
- PDK-1
- COMT
- Orphan GPCR
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- PCSK9
- REV-ERB
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- YTHDF
- Biochemical Assay Reagents
- HIV Integrase
- Keap1-Nrf2
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- Phosphorylase
- PEPCK
- CGRP Receptor
- RUNX
- DNA Stain
- PGE synthase
- MicroRNA
- Acetyl-CoA Carboxylase
- Lactate Dehydrogenase
- G-quadruplex
- Prokineticin Receptor
- ICMT
- Neuropeptide Y Receptor
- Interleukin Related
- mTOR
- SLC39 (Zinc Transporter)
- Cadherin
- Influenza Virus
- RAR/RXR
- BCL6
- Transferrin Receptor
- Protease Activated Receptor (PAR)
- Succinate Receptor 1
- Secretin Receptor
- ASCT
- Synaptic Vesicle Proteins
- NF-κB
- Reference Standards
- S-adenosylhomocysteine hydrolase (SAHH)
- GPR55
- Heme Oxygenase (HO)
- RIBOTAC
- Acetyl-CoA synthetase
- Drug Derivative
- Dengue Virus
- Bombesin Receptor
- RNA MTase
- ATTECs
- Fatty Acid Synthase (FASN)
- Oct3/4
- GPR88
- PI5P4K
- IRE1
- Nuclear Hormone Receptor 4A/NR4A
- p38 MAPK
- MCHR1 (GPR24)
- Dihydroceramide Desaturase 1 (DES1)
- Calcium Channel
- Transthyretin (TTR)
- GLUT
- N-myristoyltransferase
- Dihydroorotate Dehydrogenase
- Ligands for Target Protein for PROTAC
- GPR171
- ATGL
- DNA/RNA Synthesis
- Serine Racemase (SR)
- PI4K
- Human leukocyte immunoglobulin (Ig)-like receptors (LILR)
- DNA-PK
- mAChR
- MARCKS
- C-type Lectin-like Receptors (CTLRs)
- Reactive Oxygen Species (ROS)
- ATF6
- Enolase
- HCN Channel
- CD3
- Monocarboxylate Transporter
- Measles Virus
- IGF-1R
- ATP Citrate Lyase
- Beta-secretase
- Dystrophin
- Carboxypeptidase
- VD/VDR
- LILRB
- Ferroportin
- Thymidylate Synthase
- Pim
- IPK Superfamily
- Survivin
- Amine N-methyltransferase
- Separase
- Eukaryotic Release Factor (eRF)
- IDE
- Factor Xa
- Pyruvate Kinase
- Dopamine Transporter
- NADPH Oxidase
- PROTAC-Linker Conjugates for PAC
- PROTAC Linkers
- P2Y Receptor
- Hormone-Sensitive Lipase (HSL)
- Galectin
- Angiotensin Receptor
- Isocitrate Dehydrogenase (IDH)
- β-glucuronidase
- CD1
- CDK
- HRASLS
- Microsomal Triglyceride Transfer Protein (MTP)
- Microtubule/Tubulin
- Deubiquitinase
- GPR35
- Glycine Receptor (GlyR)
- Transcription Factor ERG
- TREM receptor
- SRPK
- Ser/Thr Protease
- HDAC
- MELK
- PIKfyve
- STING
- GnRH Receptor
- GPR119
- Tyrosinase
- Scavenger Receptor Class B type I (SR-BI）
- NEDD8-activating Enzyme
- Hedgehog
- Casein Kinase
- Pyruvate Carboxylase (PC)
- Methylenetetrahydrofolate Dehydrogenase (MTHFD)
- Polo-like Kinase (PLK)
- Beclin1
- SphK
- Arginase
- α-synuclein
- Glucosylceramide Synthase (GCS)
- Nectin-4
- Arrestin
- ACSL Family
- Legumain
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- FOXA
- CaSR
- TSPO
- TLK
- Flavivirus
- Thrombopoietin Receptor
- PANK
- AUTOTACs
- Acyltransferase
- Small Interfering RNA (siRNA)
- MAP3K
- CHIKV
- Somatostatin Receptor
- Ornithine decarboxylase (ODC)
- P-selectin
- G Protein-coupled Receptor Kinase (GRK)
- Orphan Receptor
- Phosphoramidites
- Steroid Sulfatase
- Glutathione S-transferase
- Adenosine Kinase
- HSP
- VEGFR
- CRAC Channel
- Dipeptidyl Peptidase
- TMV
- IMPDH
- Mixed Lineage Kinase
- ClpP
- 3β-HSD
- SHMT
- GSK-3
- MetAP
- GHR
- Radionuclide-Drug Conjugates (RDCs)
- Prostaglandin Receptor
- Urotensin Receptor
- ADAMTS
- Dihydropyrimidine Dehydrogenase (DPD)
- CD38
- PhosTACs
- Clathrin
- Natriuretic Peptide Receptor (NPR)
- PKC
- DNA Methyltransferase
- Neurokinin Receptor
- Hepatitis E Virus (HEV)
- ADC Payloads
- Melatonin Receptor
- Target Protein Ligand-Linker Conjugates
- Sigma Receptor
- Glucokinase
- Apelin Receptor (APJ)
- Hemoglobin
- DAPK
- Aminotransferases (Transaminases)
- Glycosyltransferase
- Orphan Nuclear Receptor
- VZV
- Exosomes
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- Ser/Thr Kinase
- Monoamine Oxidase
- SGLT
- Calpain
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- TRP Channel
- MOFs
- MAGL
- Cholecystokinin Receptor
- RSV
- GHSR
- GPR39
- Mesothelin
- STAT
- Glutaminase
- AUTACs
- Adhesion G Protein-coupled Receptors (AGPCRs)
- PPAR
- EHD Protein
- γ-secretase
- Kinesin
- Ninjurin
- Pregnane X Receptor (PXR)
- RAD51
- Neprilysin
- Histamine Receptor
- MHC
- KMO
- Nuclear Factor of activated T Cells (NFAT)
- c-Met/HGFR
- Aquaporin
- Sodium Channel
- Serpin
- MyD88
- FOXM1
- Potassium Channel
- Mps1
- Hexokinase
- Na+/K+ ATPase
- TNK1
- Progesterone Receptor
- Dopamine β-hydroxylase
- RGS Protein
- TGF-beta/Smad
- Amyloid-β
- Histone Methyltransferase
- TSSK
- Leukotriene Receptor
- Piezo Channel
- LYTACs
- MASTL
- Ack1
- Proteolytic Enzyme
- CaMK
- PKA
- PDHK
- Porcupine
- Serotonin Transporter
- Choline Kinase
- Bcr-Abl
- Gap Junction Protein
- Farnesyl Transferase
- S100 Protein
- Glycoprotein VI
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- Guanylate Cyclase
- Cyclic GMP-AMP Synthase
- Metal Nanoparticles
- PD-1/PD-L1
- Mucin
- Sex Pheromone
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- UGT
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- Carnosine-cleaving Enzyme
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- Isotope-Labeled Compounds
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- COX
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- Cytochrome P450
- SWI/SNF Complex
- RANKL/RANK
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- GlyT
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- Cannabinoid Receptor
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- LRRK2
- Pirin
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- c-Myc
- Procollagen C Proteinase
- Anion Exchangers
- Arf Family GTPase
- Protein Prenyltransferase
- Histone Acetyltransferase
- Carbonyl Reductase
- 11β-HSD
- PKG
- HOXA
- Beta-lactamase
- Na+/Ca2+ Exchanger
- Reverse Transcriptase
- ATP Synthase
- Aminopeptidase
- AMPK
- APC
- SOS1
- FOXJ
- SARS-CoV
Cat. No.: HY-W109754
CAS No.: 1776-30-3
Synonyms: 2',4'-DHC
2',4'-Dihydroxychalcone, in combination with nalidixic acid (HY-B0398), exhibits synergistic effects against E. coli by reducing membrane permeability .
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Cat. No.: HY-175334
CAS No.: 2920443-08-7
Research Areas:
DHC-286 is a molecular glue degrader targeting GSPT1. DHC-286 recruits GSPT1 to the CRL4CRBN ubiquitin ligase complex, promoting GSPT1 ubiquitination and proteasomal degradation, inducing cytotoxicity. DHC-286 is promising for research of cancers such as acute myeloid leukemia .
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Research Areas:
4,7-Dihydroxycoumarin is an EGFR inhibitor, estrogen receptor inhibitor, and progesterone receptor inhibitor. 4,7-Dihydroxycoumarin against breast cancer cells with an IC50 velue of 18.36 μg/mL. 4,7-Dihydroxycoumarin can be used for the research of breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
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