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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
141 Results for "
(E/Z)-OT-R antagonist 1
" in MedChemExpress (MCE) Product Catalog:
Products (141)
141 Results for "(E/Z)-OT-R antagonist 1" in MCE Product Catalog:
9
9 Publications Verification
Cat. No.: HY-P72566
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RN; IL-1ra; Interleukin 1 Receptor antagonist; Intracellular Interleukin-1 Receptor antagonist (IcIL-1ra); ICIL-1RA; Intracellular Interleukin-1 Receptor antagonist; IL-1RN; Intracellular IL-1 Receptor antagonist Type II; IL1RA; Type II Interleukin-1 R
Species:
Mouse
Source:
E. coli
5
5 Cited Publications
Cat. No.: HY-P7029
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RN; IL-1ra; Interleukin 1 Receptor antagonist; Intracellular Interleukin-1 Receptor antagonist (IcIL-1ra); ICIL-1RA; Intracellular Interleukin-1 Receptor antagonist; IL-1RN; Intracellular IL-1 Receptor antagonist Type II; IL1RA; Type II Interleukin-1 R
Species:
Human
Source:
E. coli
2
2 Cited Publications
Target:
Research Areas:
CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases .
2
2 Cited Publications
Target:
Research Areas:
CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 hydrochloride is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases .
2
2 Cited Publications
Cat. No.: HY-P7029A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RN; IL-1ra; Interleukin 1 Receptor antagonist; Intracellular Interleukin-1 Receptor antagonist (IcIL-1ra); ICIL-1RA; Intracellular Interleukin-1 Receptor antagonist; IL-1RN; Intracellular IL-1 Receptor antagonist Type II; IL1RA; Type II Interleukin-1 R
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P72570
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1F10; MGC119832; Interleukin 1 Family Member 10; MGC119833; IL-1HY2; MGC11983; IL1-Theta; IL1HY2; IL-1F10; Interleukin-1 Receptor antagonist-Like FIL1 Theta; FKSG75; Interleukin 1 Family, Member 10 (Theta); IL-38; Interleukin 1 Family Member 10 (Theta)
Species:
Human
Source:
E. coli
1
1 Cited Publications
Synonyms: GPR183 antagonist-1
Target:
Research Areas:
SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC50 value of 28.5 nM, can antagonize 7α, 25-OHC–induced calcium mobilization with IC50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice .
1
1
1 Cited Publications
Cat. No.: HY-P7822
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CER1; DAN Domain Family Member 4; Cerberus 1, DAN Family BMP antagonist; Cerberus 1 (Xenopus Laevis) Homolog (Cysteine Knot Superfamily); DAND4; Cerberus 1, Cysteine Knot Superfamily, Homolog (Xenopus Laevis); Cerberus-Related Protein; Cerberus 1, Cystein
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71601Y
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1F10; MGC119832; Interleukin 1 Family Member 10; MGC119833; IL-1HY2; MGC11983; IL1-Theta; IL1HY2; IL-1F10; Interleukin-1 Receptor antagonist-Like FIL1 Theta; FKSG75; Interleukin 1 Family, Member 10 (Theta); IL-38; Interleukin 1 Family Member 10 (Theta)
Species:
Mouse
Source:
E. coli
Target:
Research Areas:
TSHR antagonist S37a is a highly selective thyrotropin receptor (TSHR) antagonist, with potential for the treatment of Graves' orbitopathy .
Research Areas:
FPR1 antagonist 1 (compound 24a) is a formyl peptide receptor 1 (FPR1) antagonist with an IC50 of 25 nM. FPR1 antagonist 1 inhibits cell growth through a combined effect on cell proliferation and apoptosis and reduces cell migration, while inducing an increase in angiogenesis .
Target:
Research Areas:
GPR34 receptor antagonist 3 (Compound 5e) is a class of GRP34 antagonists, IC50 is 0.680 μM. GPR34 receptor antagonist 3 inhibited ERK1/2 phosphorylation induced by lysophosphatidylserine in a dose-dependent way without obvious cytotoxicity. GPR34 receptor antagonist 3 shows antisensory activity in mouse neuropathic pain model .
Cat. No.: HY-176550
CAS No.: 1787243-08-6
Target:
Research Areas:
ASIC1a antagonist-1 (Compound 5b) is an orthosteric noncompetitive Acid sensing ion channels 1a (ASIC1a) antagonist with an IC50 of 27 nM (pH 6.7). ASIC1a antagonist-1 shifts pH dependence of ASIC1a activation and inhibits its maximal evoked response. ASIC1a antagonist-1 completely inhibits long-term potentiation (LTP) induction in CA3-CA1 pathway. ASIC1a antagonist-1 can be used for brain diseases and pathologies research .
Cat. No.: HY-168098
CAS No.: 3098518-23-8
Target:
Research Areas:
P2Y6R antagonist 1 (compound 5ab) is a selective, orally active P2Y6R antagonist with an IC50 value of 19.6 nM. P2Y6R antagonist 1 has anti-inflammatory activity .
Target:
Research Areas:
EP3 antagonist 3 (compound 2) is an orally active, potent and selective EP3 antagonist, with a pKi of 8.3. EP3 antagonist 3 shows excellent pharmacokinetic properties. EP3 antagonist 3 can be used for overactive bladder (OAB) research .
Synonyms: AHR antagonist 7
Target:
Research Areas:
CAY10464 (AHR antagonist 7; compound 4j) is a selective and high-affinity aryl hydrocarbon receptor (AhR) antagonist with a Ki of 1.4 nM .
Target:
Research Areas:
Bcl-xL antagonist 2 is a potent, selective, and orally active antagonist of BCL-XL with an IC50 and Ki of 0.091 μM and 65 nM, respectively. Bcl-xL antagonist 2 promotes the apoptosis of cancer cells. Bcl-xL antagonist 2 has the potential for the research of the chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma (NHL) .
Target:
Research Areas:
mGluR5 antagonist-1 is an orally active mGluR5 antagonist with an IC50 value of 11.5 nM. mGluR5 antagonist-1 has anti-depressant effect. mGluR5 antagonist-1 can be used for the study of depressive disorder .
Cat. No.: HY-157493
CAS No.: 936345-34-5
Target:
Research Areas:
PR antagonist 1 (compound 8) is a selective progesterone receptor (PR) antagonist, and can be used for the research of a variety of progesterone-related diseases and disorders such as endometriosis and uterine fibroids .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
