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Results for "

2'-O-C22 hydrocarbon chain

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aryl Hydrocarbon Receptor (141) ELOVL (5) 5-HT Receptor (1) ABA Receptor (1) Acetolactate Synthase (ALS) (9) Acetyl-CoA Carboxylase (1) Acetyl-CoA synthetase (3) ACSL Family (4) Acyltransferase (7) ADC Antibody (3) ADC Linker (53) Adenosine Receptor (4) Adenylate Cyclase (1) Akt (14) Aldose Reductase (1) Amino Acid Decarboxylase (1) Amino Acid Derivatives (19) Amino acid Transporter (2) Aminopeptidase (2) Aminotransferases (Transaminases) (3) AMPK (25) Amylases (1) Amyloid-β (9) Androgen Receptor (10) Angiotensin-converting Enzyme (ACE) (4) ANGPTL (2) Antibiotic (29) Antibody-Drug Conjugates (ADCs) (1) Antifolate (2) Apolipoprotein (1) Apoptosis (116) Arp2/3 Complex (2) ASCT (1) Atg8/LC3 (1) ATP Synthase (10) ATP-binding cassette (ABC) transporters (1) Autophagy (41) Bacterial (124) Bcl-2 Family (8) Biochemical Assay Reagents (705) Btk (1) c-Fms (2) c-Met/HGFR (4) c-Myc (5) C-type Lectin-like Receptors (CTLRs) (2) Cadherin (3) Calcium Channel (10) Calmodulin (7) CaMK (2) 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Xanthine Oxidase (2) β-catenin (2) β-glucuronidase (1)
By Research Areas:	Cancer (585) Cardiovascular Disease (148) Endocrinology (37) Infection (253) Inflammation/Immunology (530) Metabolic Disease (396) Neurological Disease (205)
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Oligonucleotides:	Thymine Nucleotide (2) Thickeners (1) Nucleotide Analogs (13) Adenine (1) mRNA (2) Phospholipids (26) Other Phosphoramidite (1) Bases (2) Antisense Oligonucleotides (3) Cytidine Nucleotide (1) Adenine Nucleotide (2) Guanine (2) Interferon & Receptors (1) Pegylated Lipids (19) Guanine Nucleotide (2) Aptamers (1) CpG ODNs (1) Emulsifiers (2) Cationic Lipids (12) Cytosine (3) Polymers (7) Uracil (2) Phosphoramidites (9) Interleukin & Receptors (1)

2478

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

568

Biochemical Assay Reagents

145

Peptides

MCE Kits

360

Inhibitory Antibodies

314

Natural
Products

287

Recombinant Proteins

225

Isotope-Labeled Compounds

336

Antibodies

100

Click Chemistry

100

Oligonucleotides

GMP Molecules

Targets Recommended: Aryl Hydrocarbon Receptor Branched Chain Amino Acid Transaminase (BCAT) ELOVL

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7819

Pristane 1 Publications Verification Norphytane	Others	Inflammation/Immunology
Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil . Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat .

HY-139411

White mineral oil Paraffin oil	Environmental Pollutants Biochemical Assay Reagents	Infection
White mineral oil is the highly refined mineral oil, and is composed of saturated aliphatic and alicyclic nonpolar hydrocarbons. White mineral oil is biologically and chemically stable, and doesn’t support pathogenic bacterial growth. White mineral oil can resist moisture, extend, soften, smoothen, and lubricate .

HY-132580

Tofersen 2 Publications Verification BIIB067; ISIS-SOD1Rx; ISIS 333611	SOD	Neurological Disease
Tofersen (BIIB067) is an antisense oligonucleotide and SOD1 mRNA inhibitor with an IC₅₀ of 320 pM. Tofersen mediates RNase H-dependent degradation of SOD1 mRNA to reduce SOD1 protein levels in cerebrospinal fluid and serum. Tofersen downregulates cerebrospinal fluid neurofilament light chain, neurofilament heavy chain, amyloid-beta 1-40, amyloid-beta 1-42, neuropeptide Y, ubiquitin C-terminal hydrolase L1, neuropentraxins 1, 2, R, corticotropin-releasing hormone, IL-15, and serum neurofilament light chain, neurofilament heavy chain. Tofersen can be used for the research of superoxide dismutase 1-associated amyotrophic lateral sclerosis .

HY-P3479

Insulin (swine)	Insulin Receptor	Metabolic Disease
Insulin (swine) is an orally active insulin derived from pigs. Insulin (swine) when administered orally acts as an antigen to reduce the severity of pancreatic lymphocyte infiltration, but has no metabolic effect on blood glucose levels. Insulin (swine) increases glucose oxidation, stimulates lipogenesis, and lowers blood glucose levels. Insulin (swine) can be used in diabetes research .

HY-W007355

Skatole 5+ Cited Publications 3-Methylindole; 3-Methyl-1H-indole	Environmental Pollutants Apoptosis Endogenous Metabolite p38 MAPK Aryl Hydrocarbon Receptor	Others
Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

HY-B0845

Prochloraz 1 Publications Verification BTS 40542	Environmental Pollutants Estrogen Receptor/ERR Aryl Hydrocarbon Receptor Fungal Androgen Receptor	Infection Endocrinology
Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC₅₀ values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the *aryl hydrocarbon* receptor (AhR) having an EC₅₀** of 1 μM .

HY-Z11724

*Semaglutide Main Chain* (9-37)**	Drug Derivative	Metabolic Disease
Semaglutide Main Chain (9-37) is a peptide starting material in the synthesis of semaglutide (HY-114118) .

HY-P99481

Birtamimab NEOD001	Amyloid-β	Neurological Disease
Birtamimab (NEOD001) is an investigational monoclonal antibody that specifically and selectively target and clear the amyloid. Birtamimab can be used for the research of light chain amyloidosis .

HY-18619

YL-109 2 Publications Verification	Aryl Hydrocarbon Receptor	Cancer
YL-109 is an antitumor agent that can induce carboxyl terminus of Hsp70-interacting protein (CHIP) expression through *aryl hydrocarbon* receptor (AhR)** signaling. YL-109 has ability to inhibit breast cancer cell growth and invasiveness .

HY-111449

BAY-218 2 Publications Verification AHR antagonist 1	Aryl Hydrocarbon Receptor	Inflammation/Immunology Cancer
BAY-218 (AHR antagonist 1) is an *aryl hydrocarbon* receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC₅₀** of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses .

HY-B1027

4-Nonylphenol polyethoxylate Nonoxynol; Nonoxinol	Environmental Pollutants Biochemical Assay Reagents	Others
4-Nonylphenol polyethoxylate (Nonoxynol) is a non-ionic surfactant. 4-Nonylphenol polyethoxylate forms degradation products including 4-nonylphenol and short ethoxyl chain polyethoxylates. 4-Nonylphenol polyethoxylate generates degradation products that exhibit estrogenic activity, persist in aquatic environments, and bioaccumulate in the food chain .

HY-W014075

1-Hydroxypyrene	Aryl Hydrocarbon Receptor Cytochrome P450 Collagen	Inflammation/Immunology
1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for *aryl hydrocarbon* receptor (AhR**) and can lead to renal fibrosis .

HY-P2511

*Insulin β Chain* Peptide (15-23)**	Transmembrane Glycoprotein	Metabolic Disease
Insulin β Chain Peptide (15-23) is one of the earliest antigenic epitopes to which CD8 T-cells respond .

HY-164583

*DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite*	Phosphoramidites DNA/RNA Synthesis	Others
DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite is an RNA phosphoramidite monomer. DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite allows site-specific introduction of a 2'-O-C22 lipophilic modification at adenosine positions to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipophilicity and tissue uptake efficiency of dsRNA. DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite can be used for the construction and mechanism research of nucleic acid silencing molecules .

HY-W013570

Acenaphthylene 1 Publications Verification	Environmental Pollutants Drug Intermediate	Others
Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .

HY-103221

MeBIO	Aryl Hydrocarbon Receptor GSK-3 CDK	Others
MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC₅₀ of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively .

HY-Y1422H

Lipase,Candida cylindracea (Immobilized)	Environmental Pollutants Biochemical Assay Reagents Lipase	Others
Lipase, Candida cylindracea (Immobilized) is an immobilized hydrolase and biocatalyst with relaxed positional and substrate specificity. Lipase, Candida cylindracea (Immobilized) can target primary and secondary ester bonds to completely hydrolyze triglycerides into fatty acids and glycerol, producing only trace amounts of monoglycerides. Lipase, Candida cylindracea (Immobilized) exhibits chain specificity, with a relatively fast hydrolysis rate for oleic acid and lauric acid chains, and the slowest hydrolysis rate for stearic acid chains. Lipase, Candida cylindracea (Immobilized) shows high catalytic activity toward long-chain triglycerides under the conditions of pH 8.0 and 37°C .

HY-164582

*DMTr-2'-O-C22-rC(Ac)-3'-CE-Phosphoramidite*	Phosphoramidites DNA/RNA Synthesis	Others
DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite is an RNA phosphoramidite monomer. DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite enables site-specific introduction of 2'-O-C22 lipophilic modification at cytidine positions during oligonucleotide synthesis, which is used to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipophilicity and tissue uptake efficiency of dsRNA. Construction and mechanism study of DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite nucleic acid silencing molecules .

HY-P3432

DfTat	Biochemical Assay Reagents	Others
DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .

HY-N9929

Docosane 1 Publications Verification	Environmental Pollutants Biochemical Assay Reagents	Others
Docosane is a straight-chain alkane. Docosane can be used to synthesize structural composites with thermal energy storage/release capabilities. Docosane can also be used to prepare thermosensitive antipyretic analgesics .

HY-P1826

CLIP (86-100)	CD74	Inflammation/Immunology Cancer
CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site .

HY-W088037

Tridecane	Environmental Pollutants	Others
Tridecane is a short chain aliphatic hydrocarbon containing 13 carbon atoms. Tridecane is an volatile oil component isolated from essential oil of Piper aduncum L. Tridecane is a stress compound released by the brown marmorated stink bugs stress compound .

HY-139276

Pal-Glu(OSu)-OH	GLP Receptor	Others
Pal-Glu(OSu)-OH is a side chain of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used for type 2 diabetes mellitus research .

HY-164581

*DMTr-2'-O-C22-rG(ibu)-3'-CE-Phosphoramidite*	Phosphoramidites DNA/RNA Synthesis	Others
DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite is an RNA phosphoramidite monomer for oligonucleotide synthesis. DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite enables site-specific introduction of 2'-O-C22 lipophilic modification at guanosine positions to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipid solubility and tissue uptake efficiency of dsRNA. DMTr-2'-O-C22-rG (ibu)-3'-CE-Phosphoramidite can be used for the construction and mechanism research of nucleic acid silencing molecules .

HY-W105775

Diammonium succinate Ammonium succinate	Environmental Pollutants Biochemical Assay Reagents	Others
Diammonium succinate (Ammonium succinate) is a hydrophobic hydrocarbon compound that can be used to study its interaction with microbial cells, especially the mechanisms of degradation and bioavailability. Diammonium succinate is a biomaterial or organic compound that can be used as a biomaterial or organic compound related to life science research.

HY-23499

Indeno[1,2,3-cd]pyrene	Environmental Pollutants Aryl Hydrocarbon Receptor	Inflammation/Immunology Cancer
Indeno[1,2,3-cd]pyrene is a polycyclic aromatic hydrocarbon with moderate cytotoxicity in human pulmonary alveolar epithelial cells HPAEpiC. Indeno[1,2,3-cd]pyrene enhances allergic lung infammation via aryl hydrocarbon receptor .

HY-140341A

Sulfo-NHS-Acetate sodium	PROTAC Linkers	Others
Sulfo-NHS-Acetate sodium is an alkyl chain-based PROTAC linker. Sulfo-NHS-Acetate sodium can be used in the synthesis of PROTACs .

HY-W007355R

Skatole (Standard) 3-Methylindole (Standard); 3-Methyl-1H-indole (Standard)	Reference Standards Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Apoptosis	Others
Skatole (Standard) is the analytical standard of Skatole. This product is intended for research and analytical applications. Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

HY-N1077

Vomifoliol	Cholinesterase (ChE) Endogenous Metabolite	Others
Vomifoliol, a compound related to abscisie acid (ABA), has a modified 2,4-pentadiene side chain and has activity equal to that displayed by ABA. Vomifoliol exhibits antiacetylcholinesterase activity and displays moderate antileishmanial activity .

HY-P2981

Carboxypeptidase C Carboxypeptidase Y; EC 3.4.16.1	Carboxypeptidase	Others
Carboxypeptidase C is a carboxypeptidase, is often used in biochemical studies. Carboxypeptidase C removes COOH-terminal lysine, arginine, and proline, as well as all other neutral, aliphatic, aromatic, and the acidic protein amino acids of a peptide chain .

HY-143700

18:0 DAP	Biochemical Assay Reagents	Others
18:0 DAP is a cationic or ionizable lipid with no unsaturated bonds in its hydrocarbon chain. The mRNA encapsulation efficiency of 18:0 DAP is 0%. 18:0 DAP cannot form functional lipid nanoparticles suitable for mRNA delivery .

HY-P990818

*Anti-Rat FcRn heavy chain* heterodimers Antibody (1G3)**	Fc Receptor (FcR)	Inflammation/Immunology
Anti-Rat FcRn heavy chain heterodimers Antibody (1G3) is an anti-rat *FcRn heavy chain* heterodimers** IgG1 monoclonal antibody. Anti-Rat FcRn heavy chain heterodimers Antibody (1G3) can effectively bind to FcRn and competitively inhibit the binding of IgG to FcRn. Anti-Rat FcRn heavy chain heterodimers Antibody (1G3) can reduce the total serum IgG level. Anti-Rat FcRn heavy chain heterodimers Antibody (1G3) can be used for researches on autoimmune conditions such as experimental autoimmune myasthenia gravis (EAMG). The recommend isotype control of Anti-Rat FcRn heavy chain heterodimers Antibody (1G3): Mouse IgG1 kappa, Isotype Control (HY-P99977) .

HY-W414466

C20-Dihydrosphingosine D-Erythro-sphinganine C20 chain	Biochemical Assay Reagents	Metabolic Disease
C20-Dihydrosphingosine (D-Erythro-sphinganine C20 chain) is an ester product.

HY-200314

*DMTr-2'-O-C22-rU-3'-CE-phosphoramidite*	Nucleoside Antimetabolite/Analog Phosphoramidites	Metabolic Disease
DMTr-2'-O-C22-rU-3'-CE-Phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.

HY-P10204

FZD7 antagonist 1	Wnt	Cancer
FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the wnt3a with IC₅₀ value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors .

HY-W012278

Benz[a]anthracene Tetraphene	Environmental Pollutants Aryl Hydrocarbon Receptor	Others
Benz[a]anthracene (Tetraphene) (Compound 92) is a ligand for the aryl hydrocarbon receptor (AhR) with a pIC₅₀ of 7.319. Benz[a]anthracene is a polycyclic aromatic hydrocarbon (PAH) that can be detected in spruce needles near aluminum smelters .

HY-W012857

4-Methylethylbenzene	Drug Intermediate	Others
4-Methylethylbenzene is a volatile aromatic hydrocarbon compound. 4-Methylethylbenzene can be isolated from the essential oil of the peels of Juglans nigra L. .

HY-23498

Benzo[k]fluoranthene	Environmental Pollutants Endogenous Metabolite	Others
Benzo[k]fluoranthene is a polycyclic aromatic hydrocarbon (PAH) that is carcinogenic and genotoxic .

HY-104026B

L-Kynurenine sulfate	Endogenous Metabolite Aryl Hydrocarbon Receptor	Inflammation/Immunology
L-Kynurenine sulfate, an *aryl hydrocarbon* receptor (AHR**) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .

HY-W725399

1,2-Dilignoceroyl-sn-glycero-3-phosphocholine DLiPC; PC24	Drug Intermediate Endogenous Metabolite	Others
1,2-Dilignoceroyl-sn-glycero-3-phosphocholine (DLiPC) is a long-chain diacyl phospholipid characterized by its C24 saturated hydrocarbon chains and serves as a significant precursor for eicosanoids.

HY-Y1911

*Mid-chain* triglyceride of caprylic/caprolic acid**	Biochemical Assay Reagents	Others
Mid-chain triglyceride of caprylic/caprolic acid can be used as a co-solvent.

HY-E70263

04:1 Coenzyme A trisodium	Endogenous Metabolite	Metabolic Disease
04:1 Coenzyme A is a biochemical reagent that is a specific form of coenzyme A (CoA), "04:1" usually indicates that the acyl chain of the CoA contains four carbon atoms and one double bond. 04:1 Coenzyme A can be used to study specific biochemical reactions or pathways .

HY-W127332

*6-OAc PtdGlc(di-acyl Chain)*	Biochemical Assay Reagents	Others
6-OAc PtdGlc(di-acyl Chain) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P4890

Relaxin H3 (human)	RXFP Receptor	Neurological Disease
Relaxin H3 (human) is a kind of relaxin peptide. Relaxin H3 (human) exerts antifibrotic actions via RXFP1 .

HY-P10693

CZEN-002	TNF Receptor Bacterial	Infection Inflammation/Immunology
CZEN-002 is a derivative of alpha-melanocyte-stimulating hormone that has anti-inflammatory and antibacterial properties, inhibiting the production of TNF-α .

HY-P11246

A13:B7-24-GG	RXFP Receptor	Metabolic Disease
A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a K_i value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (K_i = 602.56 nM) and an inhibitory effect on cAMP (EC₅₀) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC₅₀ of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation .

HY-169753

AHR-IN-1	Aryl Hydrocarbon Receptor	Cancer
AHR-IN-1 (1-103) is an aryl hydrocarbon receptor (AHR) inhibitor with IC₅₀ < 0.5 μM .

HY-W718719

Tricyclene	Others	Others
Tricyclene is a natural bicyclic monoterpene hydrocarbon, and it is one of the main components in the essential oil of Salvia aegyptiaca L .

HY-W026772R

Fluorene (Standard)	Fluorescent Dye Reference Standards	Others
Fluorene (Standard) is the analytical standard of Fluorene. This product is intended for research and analytical applications. Fluorene, a polycyclic aromatic hydrocarbon (PAH), is a precursor to other fluorene compounds. Fluorene and its derivative?can be used as a precursor to fluorene-based dyes .

HY-104026CS

L-Kynurenine-13C10 sulfate hemihydrate	Aryl Hydrocarbon Receptor Endogenous Metabolite	Inflammation/Immunology
L-Kynurenine- ¹³C10 (sulfate hemihydrate) is the ¹³C labeled L-Kynurenine sulfate. L-Kynurenine sulfate hemihydrate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6782

Oligomycin 100+ Cited Publications	Infection Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Disease Research Anticancer Disease Research Fields Source Classification	Oxidative Phosphorylation ATP Synthase Fungal Antibiotic
Oligomycin, an antifungal antibiotic, is an inhibitor of H ⁺-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells .

HY-104026

L-Kynurenine 20+ Cited Publications	Cardiovascular Disease Structural Classification Human Gut Microbiota Metabolites Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields	Aryl Hydrocarbon Receptor Endogenous Metabolite
L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an *aryl hydrocarbon* receptor** agonist.

HY-N6707

Triacsin C 5+ Cited Publications WS 1228A; FR 900190	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	ACSL Family Parasite
Triacsin C (WS 1228A), is an orally active and intracellular *long-chain* acyl-CoA synthetases (ACSL*) inhibitor, which can be isolated from Streptomyces aureofaciens*. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C exhibits highly inhibitory effect against rotavirus replication .

HY-N0111

Coenzyme Q10 10+ Cited Publications CoQ10; Ubiquinone-10; Ubidecarenone	Neurological Disease Classification of Application Fields Anti-aging Metabolic Disease Endogenous metabolite Quinones Human Gut Microbiota Metabolites Microorganisms Benzene Quinones Inflammation/Immunology Disease Research Fields Source Classification Cancer	Endogenous Metabolite Reactive Oxygen Species (ROS) Ferroptosis
Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-N0486

L-Leucine 15+ Cited Publications Leucine	Structural Classification Metabolic Disease Amino acids Endogenous metabolite Source Classification	mTOR Endogenous Metabolite Ligands for E3 Ligase
L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-N7819

Pristane 1 Publications Verification Norphytane	other families Classification of Application Fields Terpenoids Marine natural products Other marine organisms Diterpenoids Plants Inflammation/Immunology Disease Research Fields Source Classification	Others
Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil . Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat .

HY-N0771

L-Isoleucine 5+ Cited Publications	Classification of Application Fields Endocrine diseases Amino acids Plants Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms other families Disease markers Other Diseases Nervous System Disorder Disease Research Fields Cardiovascular System Disorder Source Classification	Endogenous Metabolite
L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro .

HY-N0178

Diosmin 15+ Cited Publications	Cardiovascular Disease Flavonoids Classification of Application Fields Flavones Rutaceae Plants Citrus Disease Research Fields Source Classification	Aryl Hydrocarbon Receptor
Diosmin is a flavonoid found in a variety of citrus fruits and also an agonist of the *aryl hydrocarbon* receptor (AhR**).

HY-N0170

Indole-3-carbinol 15+ Cited Publications Indole-3-methanol	Alkaloids other families Classification of Application Fields Plants Endogenous metabolite Disease Research Fields Indole Alkaloids Source Classification Cancer	NF-κB Aryl Hydrocarbon Receptor E1/E2/E3 Enzyme Endogenous Metabolite
Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an *Aryl hydrocarbon* receptor (AhR) agonist, and an inhibitor of WWP1** (WW domain-containing ubiquitin E3 ligase 1).

HY-W014787

Decanedioic acid 1 Publications Verification Sebacic acid	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Source Classification	Environmental Pollutants Endogenous Metabolite
Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency .

HY-W014502

D-Kynurenine	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Cancer	Aryl Hydrocarbon Receptor Endogenous Metabolite
D-kynurenine, a metabolite of D-tryptophan, can serve as the bioprecursor of kynurenic acid (KYNA) and 3-hydroxykynurenine. D-Kynurenine is an agonist for G protein-coupled receptor, GPR109B. D-Kynurenine is a substrate in a fluorometric assay of D-amino acid oxidase. D-kynurenine promotes epithelial-to-mesenchymal transition via activating *aryl hydrocarbon* receptor (AHR)** .

HY-W011910

Potassium 1H-indol-3-yl sulfate 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Aryl Hydrocarbon Receptor Cytochrome P450 UGT Interleukin Related
Potassium 1H-indol-3-yl sulfate is a metabolite of tryptophan, produced by intestinal microorganisms and combined with sulfate in the liver before entering the circulatory system. Potassium 1H-indol-3-yl sulfate is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) and a urinary toxin. Potassium 1H-indol-3-yl sulfate can be used for research on kidney diseases .

HY-104026R

L-Kynurenine (Standard) 20+ Cited Publications	Structural Classification Alkaloids Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Aryl Hydrocarbon Receptor Endogenous Metabolite
L-Kynurenine (Standard) is the analytical standard of L-Kynurenine. This product is intended for research and analytical applications. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an *aryl hydrocarbon* receptor** agonist.

HY-W007355

Skatole 5+ Cited Publications 3-Methylindole; 3-Methyl-1H-indole	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Apoptosis Endogenous Metabolite p38 MAPK Aryl Hydrocarbon Receptor
Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

HY-112177

Myxothiazol	Infection Microorganisms Antifungal Classification of Application Fields Antibiotics Disease Research Disease Research Fields Other Antibiotics Source Classification	Fungal Mitochondrial Metabolism Antibiotic
Myxothiazol, an antifungal antibiotic, is a mitochondrial electron transport chain complex III (bc1 complex) inhibitor. Myxothiazol inhibits the growth of many yeasts and fungi at concentrations between 0.01 and 3 μg/ml .

HY-101415

Coenzyme Q9 1 Publications Verification Ubiquinone Q9; CoQ9; Ubiquinone 9	Cardiovascular Disease Quinones Microorganisms Classification of Application Fields Benzene Quinones Endogenous metabolite Disease Research Fields Source Classification	Apoptosis Endogenous Metabolite
Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis .

HY-130055

HQNO 2 Publications Verification	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Mitochondrial Metabolism
HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a K_d of 64 nM for complex III . HQNO is a potent inhibitor of mitochondrial NDH-2 in many species .

HY-113355

NADH	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite Apoptosis
NADH is an orally active dehydrogenase coenzyme that acts as a crucial electron carrier in cellular respiration and participates in ATP production. NADH promotes metabolism, supports brain function, and counteracts oxidative stress by transferring electrons to the electron transport chain. As a signaling molecule, NADH regulates multiple biological processes, including anti-apoptosis, synaptic plasticity, gene expression, and calcium homeostasis. Redox imbalance of NADH/NAD⁺ is one of the key pathological mechanisms of various diseases, such as diabetic nephropathy, neurodegenerative diseases, and ischemia-reperfusion injury.

HY-W014075

1-Hydroxypyrene	Structural Classification Natural Products Monophenols Classification of Application Fields Phenols Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Aryl Hydrocarbon Receptor Cytochrome P450 Collagen
1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for *aryl hydrocarbon* receptor (AhR**) and can lead to renal fibrosis .

HY-N0771R

L-Isoleucine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Disease markers Endocrine diseases Amino acids Nervous System Disorder Plants Endogenous metabolite Cardiovascular System Disorder Source Classification	Reference Standards Endogenous Metabolite
L-Isoleucine (Standard) is the analytical standard of L-Isoleucine. This product is intended for research and analytical applications. L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro .

HY-113285

Ureidopropionic acid 3-Ureidopropionic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields	Oxidative Phosphorylation Reactive Oxygen Species (ROS)
Ureidopropionic acid (3-Ureidopropionic acid) is a selective *mitochondrial respiratory chain* complex V inhibitor. Ureidopropionic acid induces the production of reactive oxygen species**, delayed elevation of intracellular calcium concentration, secondary energy-dependent excitotoxicity and neurodegeneration in neurons. Ureidopropionic acid promotes neuropathological changes by impairing mitochondrial energy metabolism, oxidative stress and excitotoxicity pathways. Ureidopropionic acid can be used in studies related to 3-ureidopropionase deficiency and severe propionic aciduria .

HY-N0586

Norisoboldine (+)-Laurelliptine	Alkaloids Classification of Application Fields Phenols Polyphenols Plants Lauraceae Isoquinoline Alkaloids Lindera aggregata (Sims) Kosterm. Inflammation/Immunology Disease Research Fields Source Classification	Adenosine Receptor
Norisoboldine is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis .

HY-114367

Delphinidin 3-rutinoside chloride 1 Publications Verification Delphinidin 3-O-rutinoside chloride	Structural Classification Anthocyans Flavonoids Solanum melongena L. Classification of Application Fields Phenols Polyphenols Solanaceae Plants Disease Research Fields Source Classification Cancer	Endothelin Receptor NO Synthase Myosin GLP Receptor
Delphinidin 3-rutinoside chloride is an anthocyanin component. Delphinidin 3-rutinoside chloride is isolable from the fruits of blackcurrant Ribes nigrum L. Delphinidin 3-rutinoside chloride activates the ET_B receptor and stimulates the NO/cGMP pathway. Delphinidin 3-rutinoside chloride increases cyclic guanosine monophosphate production and reduces the phosphorylation level of Myosin regulatory light chain. Delphinidin 3-rutinoside chloride stimulates GLP-1 secretion. It significantly induces relaxation of bovine ciliary muscle strips contracted by ET-1 and inhibits ET-1-induced contraction of bovine ciliary muscle strips. Delphinidin 3-rutinoside chloride is applicable to research related to type 2 diabetes .

HY-113426

Nepsilon-Acetyl-L-lysine 1 Publications Verification	Classification of Application Fields Other Diseases Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

HY-Y0624

4-Pentenoic acid	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Mitochondrial Metabolism
4-Pentenoic acid is a medium-chain unsaturated fatty acid. 4-Pentenoic acid has hypoglycemic and fatty acid oxidation inhibitory activities. 4-Pentenoic acid can affect blood glucose metabolism and energy metabolism through mechanisms such as inhibiting long-chain fatty acid oxidation, reducing gluconeogenesis, and promoting glucose utilization .

HY-W013570

Acenaphthylene 1 Publications Verification	Structural Classification Natural Products other families Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Environmental Pollutants Drug Intermediate
Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .

HY-121107

Chrysene 1 Publications Verification	Natural Products other families Classification of Application Fields Plants Disease Research Fields Source Classification Cancer	Environmental Pollutants
Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties .

HY-W015307

4-Ethyloctanoic acid	Structural Classification Nicotiana tabacum L. Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Solanaceae Plants Disease Research Fields Source Classification	Drug Derivative
4-Ethyloctanoic acid is a branched chain aliphatic carboxylic acid that can be found in blue cheeses, various cheese types, and lamb/mutton. 4-Ethyloctanoic acid is a fragrance ingredient .

HY-N0178R

Diosmin (Standard)	Structural Classification Flavonoids Flavones Rutaceae Plants Citrus Source Classification	Reference Standards Aryl Hydrocarbon Receptor
Diosmin (Standard) is the analytical standard of Diosmin. This product is intended for research and analytical applications. Diosmin is a flavonoid found in a variety of citrus fruits and also an agonist of the aryl hydrocarbon receptor (AhR).

HY-121262

Bisabolene (mixture of isomers) 1 Publications Verification Bisabolene; γ-Bisabolene	Other Terpenoids Structural Classification Microorganisms Terpenoids Source Classification	Drug Intermediate
Bisabolene (mixture of isomers) (Bisabolene) is a sesquiterpenoid plant natural product and also a hydrocarbon precursor for various industry-relevant chemicals. Bisabolene (mixture of isomers) serves as an important precursor for the production of industry-relevant chemicals such as biofuels, bioplastics, pharmaceuticals and cosmetics .

HY-N8425

Octacosanoic acid Montanic acid	Croton caudatus Geisel. Croton. Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Euphorbiaceae Plants Disease Research Fields Source Classification	Endogenous Metabolite
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-N9929

Docosane 1 Publications Verification	Structural Classification Natural Products Frullania Classification of Application Fields Frullaniaceae Other Diseases Plants Disease Research Fields Source Classification	Environmental Pollutants Biochemical Assay Reagents
Docosane is a straight-chain alkane. Docosane can be used to synthesize structural composites with thermal energy storage/release capabilities. Docosane can also be used to prepare thermosensitive antipyretic analgesics .

HY-W088037

Tridecane	Natural Products Piper aduncum L. Other Diseases Piperaceae Plants Disease Research Fields Source Classification	Environmental Pollutants
Tridecane is a short chain aliphatic hydrocarbon containing 13 carbon atoms. Tridecane is an volatile oil component isolated from essential oil of Piper aduncum L. Tridecane is a stress compound released by the brown marmorated stink bugs stress compound .

HY-N0586A

Norisoboldine hydrochloride (+)-Laurelliptine hydrochloride	Alkaloids Structural Classification Classification of Application Fields Phenols Polyphenols Plants Lauraceae Isoquinoline Alkaloids Lindera aggregata (Sims) Kosterm. Inflammation/Immunology Disease Research Fields Source Classification	Adenosine Receptor
Norisoboldine hydrochloride is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine hydrochloride, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis .

HY-W014701

1,4-Dihydroxy-2-naphthoic acid	Ketones, Aldehydes, Acids Source Classification	Aryl Hydrocarbon Receptor Cytochrome P450 Apoptosis Interleukin Related
1,4-Dihydroxy-2-naphthoic acid is an aryl hydrocarbon receptor (AhR) agonist. 1,4-Dihydroxy-2-naphthoic acid is also a bacterially derived metabolite and has anti-inflammatory activity .

HY-N7364R

(E)-β-Farnesene (Standard) trans-β-Farnesene (Standard)	Structural Classification Cannabis sativa L Terpenoids Sesquiterpenes Plants Moraceae Source Classification	Reference Standards Fungal
(E)-β-Farnesene (Standard) is the analytical standard of (E)-β-Farnesene. This product is intended for research and analytical applications. (E)-β-Farnesene (trans-β-Farnesene) is a volatile sesquiterpene hydrocarbon which can be found in Phlomis aurea Decne essential oil. (E)-β-Farnesene can be used as a feeding stimulant for the sand fly Lutzomyia longipalpis .

HY-W015444

2-Hydroxyoctanoic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
2-Hydroxyoctanoic acid is a *medium chain* acyl-CoA synthetase inhibitor with a K_i** of 500 μM .

HY-W007355R

Skatole (Standard) 3-Methylindole (Standard); 3-Methyl-1H-indole (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Reference Standards Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Apoptosis
Skatole (Standard) is the analytical standard of Skatole. This product is intended for research and analytical applications. Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

HY-N1077

Vomifoliol	Natural Products Classification of Application Fields Plants Endogenous metabolite Agricultural Research Human Gut Microbiota Metabolites Microorganisms other families Other Diseases Abscisic acid Phytohormone Disease Research Fields Source Classification	Cholinesterase (ChE) Endogenous Metabolite
Vomifoliol, a compound related to abscisie acid (ABA), has a modified 2,4-pentadiene side chain and has activity equal to that displayed by ABA. Vomifoliol exhibits antiacetylcholinesterase activity and displays moderate antileishmanial activity .

HY-N9279

Dehydromonocrotaline Monocrotaline pyrrole; MCTP; 3,8-Didehydromonocrotaline	Pyrrolizidine Alkaloids Structural Classification Alkaloids Endogenous metabolite Source Classification	Endogenous Metabolite
Dehydromonocrotaline is a mitochondrial respiratory chain complex I NADH oxidase inhibitor, with a IC₅₀ of 62.06 μM and a K_i of 8.1 μM in rats. Dehydromonocrotaline exerts non-competitive inhibitory effects by modifying cysteine thiol groups on complex I, and does not bind to the NADH-binding site. Dehydromonocrotaline dissipates mitochondrial membrane potential and reduces ATP levels. Dehydromonocrotaline can be used in studies related to hepatotoxicity, pulmonary hypertension and liver tumors .

HY-W016103

1-Hydroxy-2-naphthoic acid	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Phenols Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Bacterial Drug Intermediate
1-Hydroxy-2-naphthoic acid is a ubiquitous bicyclic intermediate metabolite in the microbial degradation process of polycyclic aromatic hydrocarbons (PAHs). 1-Hydroxy-2-naphthoic acid can be converted into 1,2-naphthalenediol, which enters the naphthalene degradation pathway and participates in the tricarboxylic acid (TCA) cycle to achieve complete mineralization .

HY-113094

Paullinic acid	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Paullinic acid is a long-chain fatty acid that has been detected in multiple biofluids, such as blood and urine.

HY-113450

10Z-Nonadecenoic acid	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite
10Z-Nonadecenoic acid is a kind of long-chain fatty acid with anti-tumor activity.

HY-N0170R

Indole-3-carbinol (Standard) Indole-3-methanol (Standard)	Alkaloids Structural Classification other families Plants Endogenous metabolite Indole Alkaloids Source Classification	NF-κB Aryl Hydrocarbon Receptor E1/E2/E3 Enzyme Endogenous Metabolite Reference Standards
Indole-3-carbinol (Standard) is the analytical standard of Indole-3-carbinol. This product is intended for research and analytical applications. Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).

HY-124422

Pentacosanoic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Plants Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate .

HY-101415R

Coenzyme Q9 (Standard) Ubiquinone Q9 (Standard); CoQ9 (Standard); Ubiquinone 9 (Standard)	Quinones Structural Classification Microorganisms Benzene Quinones Endogenous metabolite Source Classification	Reference Standards Apoptosis Endogenous Metabolite
Coenzyme Q9 (Standard) is the analytical standard of Coenzyme Q9. This product is intended for research and analytical applications. Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis .

HY-113383

2-Hydroxyvaleric acid	Source Classification	Endogenous Metabolite Lactate Dehydrogenase Biochemical Assay Reagents
2-Hydroxyvaleric acid is a medium chain α-hydroxy fatty acid. 2-Hydroxyvaleric acid is an activator in fat metabolism of palmitic acid-1-C ¹⁴. 2-hydroxyvaleric acid is also used as a staining agent for measuring tissue-specific Lactate dehydrogenase activity and elevated levels of 2-hydroxyvaleric acid induces lactic acidosis .

HY-N8445

Glucoerucin potassium	Glucosinolates Plants Brassicaceae Coronopus didymus Source Classification	Aryl Hydrocarbon Receptor
Glucoerucin potassium is an *aryl hydrocarbon* receptor** antagonist and is the 4-methylthio-butyl glucosinolate found in the seeds of Eruca sativa Mill .

HY-N9924

Glucoerucin	Eruca vesicaria subsp. sativa (Mill.) Thell. Glucosinolates Plants Brassicaceae Source Classification	Endogenous Metabolite Aryl Hydrocarbon Receptor
Glucoerucin is an *aryl hydrocarbon* receptor** antagonist and is the 4-methylthio-butyl glucosinolate found in the seeds of Eruca sativa Mill .

HY-N11222

Nonanoylcarnitine C9 carnitine	Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
Nonanoylcarnitine is a metabolite associated with chronic environmental exposure to polycyclic aromatic hydrocarbons (PAH) and fragmented QRS waves in acute myocardial infarction. Nonanoylcarnitine can be used as a potential biomarker for the metabolic outcome of PAH exposure and the prognosis of acute myocardial infarction .

Cat. No.	Product Name	Chemical Structure

HY-N0486S9

L-Leucine-d3 3 Publications Verification
L-Leucine-d₃ is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-N0486S1

L-Leucine-13C
L-Leucine- ¹³C is the ¹³C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-104026S

L-Kynurenine-d4 1 Publications Verification
L-Kynurenine-d₄ is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2].

HY-B1727S

Phenanthrene-d10
Phenanthrene-d₁₀ is the deuterium labeled Phenanthrene. Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) and has been frequently used as an indicator for monitoring PAH contaminated matrices . Phenanthrene induces oxidative stress and inflammation .

HY-W099580S1

Hexadecane-d34
Hexadecane-d₃₄ (n-Hexadecane-d₃₄) is the deuterium labeled Hexadecane (HY-W099580). Hexadecane (n-Hexadecane) is a saturated hydrocarbon of alkanes or paraffins and can be used as an organic solvent. Hexadecane is a component of petroleum, belongs to hydrophobic substrates, and is a model substance for studying bacterial degradation of hydrophobic compounds .

HY-B2219S4

Stearic acid-d35
Stearic Acid-d₃₅ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B2219S3

Stearic acid-d3
Stearic acid-d₃ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-N0486S

L-Leucine-d10 1 Publications Verification
L-Leucine-d₁₀ is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-N0486S2

L-Leucine-13C6
Leucine- ¹³C₆ is the ¹³C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-N0111S2

Coenzyme Q10-d9
Coenzyme Q10-d₉ is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-B2219S2

Stearic acid-13C18 1 Publications Verification
Stearic acid- ¹³C₁₈is the ¹³C-labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-N0111S

Coenzyme Q10-d6
Coenzyme Q10-d₆ is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-W011338S

Benzyl butyl phthalate-d4

Benzyl butyl phthalate-d₄ is the deuterium labeled Benzyl butyl phthalate . Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) .

HY-132429S

Potassium 1H-indol-3-yl sulfate-d5

Potassium 1H-indol-3-yl sulfate-d₅ is the deuterium labeled 3-Indoxyl Sulfate potassium. Potassium 1H-indol-3-yl sulfate is a metabolite of tryptophan, produced by intestinal microorganisms and combined with sulfate in the liver before entering the circulatory system. Potassium 1H-indol-3-yl sulfate is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) and a urinary toxin. Potassium 1H-indol-3-yl sulfate can be used for research on kidney diseases.

HY-W015309S1

Decanoic acid-d19
Decanoic acid-d₁₉9 is the deuterium labeled Decanoic acid. Decanoic acid, a component of medium chain triclycerides, is a brain-penetrant and non-competitive inhibitor of AMPA receptor. Decanoic acid has antiseizure effects .

HY-N0486S8

L-Leucine-13C6,15N
L-Leucine- ¹³C₆, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-N0486S6

L-Leucine-2-13C,15N
L-Leucine-2- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-Y0366S

Lauric acid-13C
Lauric acid- ¹³C is the ¹³C labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.

HY-W014075S

1-Hydroxypyrene-d9
1-Hydroxypyrene-d₉ is the deuterium labeled 1-Hydroxypyrene (HY-W014075). 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for *aryl hydrocarbon* receptor (AhR**) and can lead to renal fibrosis .

HY-W007355S

Skatole-d3
Skatole-d₃ is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38 .

HY-B2219S9

Stearic acid-d7
Stearic acid-d₇ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-N0486S4

L-Leucine-d7
L-Leucine-d₇ is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-N0486S3

L-Leucine-15N
L-Leucine- ¹⁵N is the ¹⁵N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-W011910S

Potassium 1H-indol-3-yl sulfate-d4

Potassium 1H-indol-3-yl sulfate-d₄ potassium is the deuterium labeled Potassium 1H-indol-3-yl sulfate. Potassium 1H-indol-3-yl sulfate is a metabolite of tryptophan, produced by intestinal microorganisms and combined with sulfate in the liver before entering the circulatory system. Potassium 1H-indol-3-yl sulfate is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) and a urinary toxin. Potassium 1H-indol-3-yl sulfate can be used for research on kidney diseases.

HY-W004284S1

Heptadecanoic acid-d33
Heptadecanoic acid-d₃₃ is the deuterium labeled Heptadecanoic acid. Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis .

HY-W004284S

Heptadecanoic acid-d3
Heptadecanoic acid-d₃ is the deuterium labeled Heptadecanoic acid. Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis .

HY-W011819S

Tetradecanedioic acid-d24
Tetradecanedioic acid-d₂₄ is the deuterium labeled Tetradecanedioic acid . Tetradecanedioic acid is an endogenous metabolite and belongs to the class of organic compounds known as long-chain fatty acids. Tetradecanedioic acid can act as a candidate biomarker for organic anion-transporting polypeptide mediated agent-agent interactions .

HY-W088037S

Tridecane-d28
Tridecane-d₂₈ is the deuterium labeled Tridecane . Tridecane is a short chain aliphatic hydrocarbon containing 13 carbon atoms. Tridecane is an volatile oil component isolated from essential oil of Piper aduncum L. Tridecane is a stress compound released by the brown marmorated stink bugs stress compound .

HY-104026S5

L-Kynurenine-13C10 sulfate hydrate
L-Kynurenine-13C10 sulfate hydrate is the C13 labeled L-Kynurenine sulfate hydrate. L-Kynurenine is an aryl hydrocarbon receptor agonist .

HY-104026S1

L-Kynurenine-d4-1
L-Kynurenine-d₄-1 is deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-W007355S1

Skatole-d8
Skatole-d₈ is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38 .

HY-130466S

Stearoyl-L-carnitine-d3 chloride
Stearoyl-L-carnitine-d₃ (chloride) is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM .

HY-Y1718S

Tridecanoic acid-d2
Tridecanoic acid-d₂ is the deuterium labeled Tridecanoic acid. Tridecanoic acid (N-Tridecanoic acid), a 13-carbon medium-chain saturated fatty acid, can serve as an antipersister and antibiofilm agent that may be applied to research bacterial infections. Tridecanoic acid inhibits Escherichia coli persistence and biofilm formation .

HY-Y1718S1

Tridecanoic acid-d25
Tridecanoic acid-d₂₅ is the deuterium labeled Tridecanoic acid. Tridecanoic acid (N-Tridecanoic acid), a 13-carbon medium-chain saturated fatty acid, can serve as an antipersister and antibiofilm agent that may be applied to research bacterial infections. Tridecanoic acid inhibits Escherichia coli persistence and biofilm formation .

HY-104026S2

L-Kynurenine-d4-1 hydrochloride
L-Kynurenine-d₄-1 hydrochloride is the deuterium labeled L-Kynurenine (HY-104026). L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an *aryl hydrocarbon* receptor** agonist .

HY-B0311AS

Carbidopa-d3 monohydrate
Carbidopa-d₃ (monohydrate) is the deuterium labeled Carbidopa monohydrate. Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa monohydrate is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa monohydrate inhibits pancreatic cancer cell and tumor growth .

HY-B2219S6

Stearic acid-d5
Stearic acid-d₅5 is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-B2219S7

Stearic acid-d4
Stearic acid-d₄ is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils .

HY-N0486S12

L-Leucine-d2
L-Leucine-d₂ is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-N0486S10

L-Leucine-18O2
L-Leucine- ¹⁸O₂ is the ¹⁸O-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-W015309S3

Decanoic acid-d5
Decanoic acid-d₅ is the deuterium labeled Decanoic acid. Decanoic acid, a component of medium chain triclycerides, is a brain-penetrant and non-competitive inhibitor of AMPA receptor. Decanoic acid has antiseizure effects .

HY-Y0366S3

Lauric acid-d3
Lauric acid-d₃3 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.

HY-Y0366S1

Lauric acid-d23
Lauric acid-d₂₃3 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.

HY-W013570S

Acenaphthylene-d8
Acenaphthylene-d₈ is the deuterium labeled Acenaphthylene . Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .

HY-N7819S

Pristane-d40
Pristane-d₄₀ is the deuterium labeled Pristane . Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil . Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat .

HY-135170S

Myristoyl-L-carnitine-d3 chloride
Myristoyl-L-carnitine-d₃ chloride is the deuterium labeled Myristoyl-L-carnitine chloride (HY-135170). Myristoyl-L-Carnitine Chloride is a natural long-chain glycoline, amino acid derivative .

HY-B2219S

Stearic acid-1-13C
Stearic acid-1- ¹³C is the ¹³C labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

HY-W015309S

Decanoic acid-d3
Decanoic acid-d₃ is the deuterium labeled Decanoic acid. Decanoic acid, a component of medium chain triclycerides, is a brain-penetrant and non-competitive inhibitor of AMPA receptor. Decanoic acid has antiseizure effects .

HY-W004294S1

1-Tetradecanol-d2
1-Tetradecanol-d₂ is the deuterium labeled 1-Tetradecanol . 1-Tetradecanol, isolated from Myristica fragrans, is a straight-chain saturated fatty alcohol. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity .