Alk - anaplastic lymphoma kinase Gene
Also Known as Tcrz; CD246
Species: Mus musculus
Gene Type: protein coding
Gene ID: 11682
About Alk
Chromosome 17: 72,175,967-72,911,622 reverse strand.GRCm39:CM001010.3
This gene has 3 transcripts (splice variants), 195 orthologues, 53 paralogues and is associated with 38 phenotypes. Low expression observed in reference dataset.
Summary
Predicted to enable identical protein binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in energy homeostasis; negative regulation of lipid catabolic process; and positive regulation of dendrite development. Acts upstream of or within several processes, including hippocampus development; response to environmental enrichment; and swimming behavior. Predicted to be located in axon; cell body; and plasma membrane. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human ALK (ALK receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]
Alk Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_007439.2 | NP_031465.2 | ALK tyrosine kinase receptor precursor |
Alk Protein Structure
MAM
MAM: cd06263 (269 - 427)
LDLa
LDLa: smart00192 (444 - 470)
MAM
MAM: cl27660 (483 - 638)
PTKc_ALK_LTK
PTKc_ALK_LTK: cd05036 (1112 - 1388)
PHA03247
PHA03247: cl33720 (1373 - 1579)
- 0
- 300
- 600
- 900
- 1200
- 1500
- 1621 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ALK tyrosine kinase receptor |
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(20)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-50878 | Crizotinib | Inhibitor | 99.97% | Yes |
| HY-12215 | Lorlatinib | 99.99% | Yes | |
| HY-12678 | Entrectinib | 99.26% | Yes | |
| HY-15656 | Ceritinib | Inhibitor | 99.95% | Yes |
| HY-13011 | Alectinib | Inhibitor | 99.78% | Yes |
| HY-12857 | Brigatinib | Inhibitor | 99.98% | Yes |
| HY-103022 | Repotrectinib | Inhibitor | 99.95% | Unkown |
| HY-15656A | Ceritinib dihydrochloride | Inhibitor | 99.90% | Yes |
| HY-13011A | Alectinib Hydrochloride | Inhibitor | 99.92% | Yes |
| HY-50878A | Crizotinib hydrochloride | 99.86% | Yes | |
| HY-103714 | Ensartinib | Inhibitor | 99.93% | Unkown |
| HY-103714A | Ensartinib dihydrochloride | Inhibitor | 99.73% | Unkown |
| HY-145574 | Iruplinalkib | Inhibitor | 99.62% | Unkown |
| HY-100375 | Diroximel fumarate | Activator | 99.60% | Yes |
| HY-123689 | Samidorphan | 99.04% | Unkown | |
| HY-12215R | Lorlatinib (Standard) | 99.92% | Unkown | |
| HY-13011AR | Alectinib Hydrochloride (Standard) | Inhibitor | 99.80% | Unkown |
| HY-50878B | Crizotinib acetate | Inhibitor | / | Unkown |
| HY-15656AR | Ceritinib dihydrochloride (Standard) | Inhibitor | / | Unkown |
| HY-15656R | Ceritinib (Standard) | Inhibitor | 99.72% | Unkown |
Clinical Phase
Bioactive Molecules
(26)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-15656B | Ceritinib mesylate | Inhibitor | / | Phase 4 |
| HY-156467 | Neladalkib | 99.90% | Phase 3 | |
| HY-172412 | Alixorexton | Agonist | 99.96% | Phase 3 |
| HY-172412A | Alixorexton enantiomer | Agonist | 99.42% | Phase 3 |
| HY-112801 | F-1 | Inhibitor | 98.03% | Phase 3 |
| HY-180970 | TD-004 | Degrader | / | Phase 3 |
| HY-N0679S | Retinyl acetate-d3 | / | Phase 3 | |
| HY-19928 | Vactosertib | Inhibitor | 99.53% | Phase 2 |
| HY-103021 | LY3200882 | Inhibitor | 99.87% | Phase 2 |
| HY-117887 | Fidrisertib | Inhibitor | 98.58% | Phase 2 |
| HY-145608 | Zilurgisertib | Inhibitor | 98.25% | Phase 2 |
| HY-172240 | Tosposertib | Inhibitor | 99.89% | Phase 2 |
| HY-17603 | Belizatinib | Inhibitor | 99.62% | Phase 2 |
| HY-16590 | X-376 | Inhibitor | 98.10% | Phase 2 |
| HY-136773 | KER047 | Inhibitor | 98.80% | Phase 2 |
| HY-109179A | Itacnosertib hydrochloride | Inhibitor | 99.43% | Phase 2 |
| HY-109084A | Conteltinib tetrahydrochloride | Inhibitor | 99.60% | Phase 2 |
| HY-136788A | ALK4290 dihydrochloride | Inhibitor | / | Phase 2 |
| HY-169482 | ALK protein ligand-1 | Inhibitor | / | Phase 2 |
| HY-15841 | CEP-37440 | Inhibitor | 99.91% | Phase 1 |
| HY-139279 | Zotizalkib | Inhibitor | 98.02% | Phase 1 |
| HY-155163 | APG-2449 | Inhibitor | 98.93% | Phase 1 |
| HY-13326 | ASP3026 | 99.88% | Phase 1 | |
| HY-135366 | HPN-01 | Inhibitor | 98.61% | Phase 1 |
| HY-142287 | Con B-1 | Inhibitor | / | Phase 1 |
| HY-16769 | Panulisib | / | Phase 1 |
Inhibitory Antibodies
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-P99353 | Ascrinvacumab | Inhibitor | 97.45% | Phase 2 |
| HY-P99752 | Nemvaleukin alfa | 99.50% | Phase 2 | |
| HY-P990022 | Prafnosbart | Inhibitor | / | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(290)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-10431 | SB-431542 | Inhibitor | 99.85% | Unkown |
| HY-10432 | A 83-01 | Inhibitor | 99.41% | Unkown |
| HY-13418A | Dorsomorphin | Inhibitor | 99.91% | Unkown |
| HY-12071 | LDN193189 | Inhibitor | 99.72% | Unkown |
| HY-13418 | Dorsomorphin dihydrochloride | Inhibitor | 99.91% | Unkown |
| HY-13012 | RepSox | Inhibitor | 99.92% | Unkown |
| HY-12043 | SB 525334 | Inhibitor | 99.97% | Unkown |
| HY-12071B | LDN193189 dihydrochloride | Inhibitor | 99.50% | Unkown |
| HY-12071A | LDN193189 Tetrahydrochloride | Inhibitor | 99.79% | Unkown |
| HY-10432A | A 83-01 sodium | Inhibitor | 98.03% | Unkown |
| HY-131442 | Alkyne-phenol | 99.72% | Unkown | |
| HY-13521 | SB-505124 | Inhibitor | 99.73% | Unkown |
| HY-W040304 | Alkynyl Palmitic Acid | 99.90% | Unkown | |
| HY-16712 | LDN-214117 | Inhibitor | 99.54% | Unkown |
| HY-12278 | K02288 | Inhibitor | 99.95% | Unkown |
| HY-13227 | SD-208 | Inhibitor | 99.87% | Unkown |
| HY-10326 | GW788388 | Inhibitor | 99.92% | Unkown |
| HY-13012G | RepSox (GMP) | Inhibitor | / | Unkown |
| HY-10192 | NVP-TAE 684 | 99.70% | Unkown | |
| HY-15609 | AZD-3463 | 99.31% | Unkown | |
| HY-15897 | LDN-212854 | Inhibitor | 99.62% | Unkown |
| HY-10431R | SB-431542 (Standard) | Inhibitor | 99.51% | Unkown |
| HY-12274 | ML347 | Inhibitor | 99.94% | Unkown |
| HY-112155 | MS4078 | Inhibitor | 99.72% | Unkown |
| HY-12953 | R-268712 | Inhibitor | 99.92% | Unkown |
| HY-19928A | Vactosertib Hydrochloride | Inhibitor | 99.22% | Yes |
| HY-13020 | GSK1838705A | Inhibitor | 99.58% | Unkown |
| HY-150169 | THRX-144644 | Inhibitor | 99.90% | Unkown |
| HY-12071G | LDN193189 (GMP) | Inhibitor | / | Unkown |
| HY-153386 | CPD-1224 | Inhibitor | 99.83% | Unkown |
| HY-10432G | A 83-01 (GMP) | Inhibitor | / | Unkown |
| HY-111482 | SM 16 | Inhibitor | 99.82% | Unkown |
| HY-183116 | TRI-611 | Degrader | 99.07% | Unkown |
| HY-123919 | TL13-112 | Inhibitor | 98.01% | Unkown |
| HY-148234 | M4K2234 | Inhibitor | 98.31% | Unkown |
| HY-168990 | Ontunisertib | Inhibitor | 99.95% | Unkown |
| HY-123856 | MY10 | 99.86% | Unkown | |
| HY-78349 | A 77-01 | Inhibitor | 99.92% | Unkown |
| HY-109084 | Conteltinib | Inhibitor | 99.0% | Unkown |
| HY-18758 | IN-1130 | Inhibitor | 99.93% | Unkown |
| HY-160506 | PRO-6E | 99.10% | Unkown | |
| HY-12071C | LDN193189 hydrochloride | Inhibitor | 98.62% | Unkown |
| HY-144043 | ALK5-IN-8 | Inhibitor | 98.21% | Unkown |
| HY-19628 | OD36 | Inhibitor | 99.33% | Unkown |
| HY-10432R | A 83-01 (Standard) | Inhibitor | / | Unkown |
| HY-18766 | EW-7195 | Inhibitor | 98.84% | Unkown |
| HY-122856 | AZ12601011 | Inhibitor | 99.78% | Unkown |
| HY-13464 | ALK-IN-1 | Inhibitor | 99.42% | Unkown |
| HY-18030A | CEP-28122 mesylate salt | Inhibitor | 99.92% | Unkown |
| HY-112815 | ALK2-IN-2 | Inhibitor | 99.93% | Unkown |
| HY-109179 | Itacnosertib | Inhibitor | 99.06% | Unkown |
| HY-147219A | SIAIS164018 hydrochloride | 98.06% | Unkown | |
| HY-N4107 | Phyllanthin | Inhibitor | 99.97% | Unkown |
| HY-122582 | TL13-12 | Degrader | 98.16% | Unkown |
| HY-N1510 | Kaempferol 3-O-gentiobioside | Inhibitor | 99.88% | Unkown |
| HY-13521A | SB-505124 hydrochloride | Inhibitor | 98.52% | Unkown |
| HY-112156 | MS4077 | Inhibitor | 99.66% | Unkown |
| HY-136788 | ALK4290 | Inhibitor | 99.79% | Unkown |
| HY-125851 | TP-008 | Inhibitor | 99.42% | Unkown |
| HY-149591 | M4K-2009 | Inhibitor | 99.35% | Unkown |
| HY-150910 | Brigatinib C | Inhibitor | 99.72% | Unkown |
| HY-160237 | HYL001 | Inhibitor | 99.94% | Unkown |
| HY-159147 | SIAIS039 | 99.68% | Unkown | |
| HY-10327 | GW-6604 | Inhibitor | 98.0% | Unkown |
| HY-118528A | TP0427736 hydrochloride | Inhibitor | 99.91% | Unkown |
| HY-12678S1 | Entrectinib-d8 | 99.82% | Unkown | |
| HY-13783 | BIBF0775 | Inhibitor | 99.42% | Unkown |
| HY-137918 | TGF-βRI inhibitor 3 | Inhibitor | 99.16% | Unkown |
| HY-155939 | M4K2163 dihydrochloride | Inhibitor | 98.58% | Unkown |
| HY-50878S | Crizotinib-d5 | 99.60% | Unkown | |
| HY-P11354A | THR-123 TFA | / | Unkown | |
| HY-112140 | JH-VIII-157-02 | Inhibitor | 98.98% | Unkown |
| HY-152845 | Ficonalkib | Inhibitor | 98.89% | Unkown |
| HY-12273R | DMH-1 (Standard) | Inhibitor | 99.78% | Unkown |
| HY-12331 | KRCA-0008 | 96.19% | Unkown | |
| HY-136773A | KER047 succinate | Inhibitor | 99.17% | Unkown |
| HY-15358 | ALK inhibitor 2 | Inhibitor | 99.72% | Unkown |
| HY-160520 | ALK-IN-28 | Inhibitor | 99.30% | Unkown |
| HY-164397 | XMU-MP-5 | 99.00% | Unkown | |
| HY-19990 | ALK kinase inhibitor-1 | Inhibitor | 99.87% | Unkown |
| HY-13011S | Alectinib-d8 | Inhibitor | 98.09% | Unkown |
| HY-151289 | ALK5-IN-34 | Inhibitor | 98.21% | Unkown |
| HY-15801 | HG-14-10-04 | Inhibitor | 98.53% | Unkown |
| HY-173149 | CDD-2789 | Inhibitor | / | Unkown |
| HY-N4126 | 6-Demethoxytangeretin | Inhibitor | 99.37% | Unkown |
| HY-111752 | EML4-ALK kinase inhibitor 1 | Inhibitor | 98.02% | Unkown |
| HY-12678S | Entrectinib-d4 | Inhibitor | / | Unkown |
| HY-135887 | ZX-29 | 98.59% | Unkown | |
| HY-136194 | TL13-22 | Inhibitor | 99.71% | Unkown |
| HY-147219 | SIAIS164018 | / | Unkown | |
| HY-15357 | ALK inhibitor 1 | Inhibitor | 99.16% | Unkown |
| HY-156432 | ALK-IN-26 | 99.87% | Unkown | |
| HY-156467A | Neladalkib TFA | 99.70% | Unkown | |
| HY-15656S | Ceritinib-d7 | Inhibitor | 98.00% | Unkown |
| HY-169481 | AP-1 | Degrader | 97.8% | Unkown |
| HY-170928 | DA-0157 | Inhibitor | 99.59% | Unkown |
| HY-19628A | OD36 hydrochloride | Inhibitor | / | Unkown |
| HY-123689S | Samidorphan-d4 | Antagonist | / | Unkown |
| HY-123689S1 | Samidorphan-d5 | Antagonist | / | Unkown |
| HY-N12973 | Peonidin 3-arabinoside | 95.0% | Unkown | |
| HY-RS00598 | ALK Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-18030 | CEP-28122 | Inhibitor | / | Unkown |
| HY-111416 | WY-135 | Inhibitor | / | Unkown |
| HY-12215S2 | Deulorlatinib | 99.84% | Unkown | |
| HY-128569 | ALK-IN-5 | Inhibitor | / | Unkown |
| HY-128596 | ALK-IN-6 | Inhibitor | / | Unkown |
| HY-13011S1 | Alectinib-d6 | Inhibitor | 98.05% | Unkown |
| HY-132229 | LPM4870108 | Inhibitor | / | Unkown |
| HY-135509 | Lorlatinib acetate | / | Unkown | |
| HY-111277 | CEP-14513 | / | Unkown | |
| HY-131909 | CJ-2360 | Inhibitor | / | Unkown |
| HY-184540 | ALK ligand-2 | Ligand | / | Unkown |
| HY-184541 | ALK protein ligand-1-PEG2-N3 | Ligand | / | Unkown |
| HY-105369 | KF-20444 | / | Unkown | |
| HY-108230 | ALK-IN-12 | Inhibitor | / | Unkown |
| HY-110347 | Mps1-IN-1 dihydrochloride | Inhibitor | / | Unkown |
| HY-112877 | ALK-5-IN-1 | Inhibitor | / | Unkown |
| HY-116636 | KRCA-0377 | Inhibitor | / | Unkown |
| HY-117806 | TSR-011-isomer | / | Unkown | |
| HY-120387 | SMU-B | Inhibitor | / | Unkown |
| HY-120663 | KRCA-0713 | Inhibitor | / | Unkown |
| HY-12278G | K02288 (GMP) | Inhibitor | / | Unkown |
| HY-12857S | Brigatinib-13C6 | Inhibitor | / | Unkown |
| HY-12973 | ALK-IN-13 | Inhibitor | / | Unkown |
| HY-13012S | RepSox-d5 | / | Unkown | |
| HY-130794 | ALK/ROS1-IN-1 | Inhibitor | / | Unkown |
| HY-131244 | ALK-IN-9 | Inhibitor | / | Unkown |
| HY-13227G | SD-208 (GMP) | Inhibitor | / | Unkown |
| HY-136195 | TL13-110 | Inhibitor | / | Unkown |
| HY-142949 | ALK5-IN-7 | Inhibitor | / | Unkown |
| HY-142950 | ALK5-IN-6 | Inhibitor | / | Unkown |
| HY-143557 | Trk-IN-7 | Inhibitor | / | Unkown |
| HY-144423 | Trk-IN-10 | Inhibitor | / | Unkown |
| HY-144437 | ALK5-IN-9 | Inhibitor | / | Unkown |
| HY-144732 | TRK/ALK-IN-1 | Inhibitor | / | Unkown |
| HY-145855 | J-1063 | Inhibitor | / | Unkown |
| HY-146022 | SIAIS117 | Degrader | / | Unkown |
| HY-146408 | ALK-IN-21 | Inhibitor | / | Unkown |
| HY-146694 | RIPK2-IN-1 | Inhibitor | / | Unkown |
| HY-146780 | TGFβRI-IN-4 | Inhibitor | / | Unkown |
| HY-147206 | Biotin-PEG600-Alk | / | Unkown | |
| HY-147206A | Biotin-PEG1000-Alk | / | Unkown | |
| HY-147206B | Biotin-PEG2000-Alk | / | Unkown | |
| HY-147206C | Biotin-PEG3400-Alk | / | Unkown | |
| HY-147206D | Biotin-PEG5000-Alk | / | Unkown | |
| HY-147206E | Biotin-PEG10000-Alk | / | Unkown | |
| HY-147206F | Biotin-PEG20000-Alk | / | Unkown | |
| HY-147833 | ALK-IN-22 | / | Unkown | |
| HY-148246 | MU1700 | Inhibitor | / | Unkown |
| HY-149403 | J-1048 | Inhibitor | / | Unkown |
| HY-151155 | ALK-IN-23 | Inhibitor | / | Unkown |
| HY-151233 | ALK5-IN-10 | Inhibitor | / | Unkown |
| HY-151270 | ALK5-IN-25 | Inhibitor | / | Unkown |
| HY-151272 | ALK5-IN-26 | Inhibitor | / | Unkown |
| HY-151273 | ALK5-IN-27 | Inhibitor | / | Unkown |
| HY-151275 | ALK5-IN-28 | Inhibitor | / | Unkown |
| HY-151277 | ALK5-IN-29 | Inhibitor | / | Unkown |
| HY-151279 | ALK5-IN-30 | Inhibitor | / | Unkown |
| HY-151281 | ALK5-IN-31 | Inhibitor | / | Unkown |
| HY-151282 | ALK5-IN-32 | Inhibitor | / | Unkown |
| HY-151283 | ALK5-IN-33 | Inhibitor | / | Unkown |
| HY-153246 | ALK2-IN-5 | Inhibitor | / | Unkown |
| HY-153503 | ALK-IN-24 | Inhibitor | / | Unkown |
| HY-155227 | ALK/EGFR-IN-1 | / | Unkown | |
| HY-155227A | ALK/EGFR-IN-2 | Inhibitor | / | Unkown |
| HY-155227B | ALK/EGFR-IN-3 | Inhibitor | / | Unkown |
| HY-155227S | ALK/EGFR-IN-1-d5 | / | Unkown | |
| HY-156470 | Multi-kinase-IN-6 | / | Unkown | |
| HY-157391 | ALK/ROS1-IN-3 | Inhibitor | / | Unkown |
| HY-159952 | ALK5-IN-84 | Inhibitor | / | Unkown |
| HY-161350 | ALK/HDAC-IN-1 | Inhibitor | / | Unkown |
| HY-161376 | M4K2281 | Inhibitor | / | Unkown |
| HY-161377 | M4K2306 | Inhibitor | / | Unkown |
| HY-161662 | ALK5-IN-80 | Inhibitor | / | Unkown |
| HY-161749 | PROTAC ALK degrader-1 | Degrader | / | Unkown |
| HY-161750 | PROTAC ALK degrader-2 | Degrader | / | Unkown |
| HY-161910 | SH-E4A-66 | Inhibitor | / | Unkown |
| HY-163429 | J-1149 | Inhibitor | / | Unkown |
| HY-163507 | ALK5-IN-79 | Inhibitor | / | Unkown |
| HY-165284 | CM-118 | Inhibitor | / | Unkown |
| HY-167388 | PLLA5000-PEG5000-ALK | / | Unkown | |
| HY-167389 | PLLA5000-PEG3000-ALK | / | Unkown | |
| HY-167390 | PLLA5000-PEG2000-ALK | / | Unkown | |
| HY-167391 | PLLA5000-PEG1000-ALK | / | Unkown | |
| HY-167392 | PLLA4000-PEG5000-ALK | / | Unkown | |
| HY-167393 | PLLA4000-PEG3000-ALK | / | Unkown | |
| HY-167394 | PLLA4000-PEG2000-ALK | / | Unkown | |
| HY-167395 | PLLA4000-PEG1000-ALK | / | Unkown | |
| HY-167396 | PLLA3000-PEG5000-ALK | / | Unkown | |
| HY-167397 | PLLA3000-PEG3000-ALK | / | Unkown | |
| HY-167398 | PLLA3000-PEG2000-ALK | / | Unkown | |
| HY-167399 | PLLA3000-PEG1000-ALK | / | Unkown | |
| HY-167400 | PLLA2000-PEG5000-ALK | / | Unkown | |
| HY-167401 | PLLA2000-PEG3000-ALK | / | Unkown | |
| HY-167402 | PLLA2000-PEG2000-ALK | / | Unkown | |
| HY-167403 | PLLA2000-PEG1000-ALK | / | Unkown | |
| HY-167404 | PLLA1000-PEG5000-ALK | / | Unkown | |
| HY-167405 | PLLA1000-PEG3000-ALK | / | Unkown | |
| HY-167406 | PLLA1000-PEG2000-ALK | / | Unkown | |
| HY-167407 | PLLA1000-PEG1000-ALK | / | Unkown | |
| HY-167408 | PLLA10000-PEG5000-ALK | / | Unkown | |
| HY-167409 | PLLA10000-PEG3000-ALK | / | Unkown | |
| HY-167410 | PLLA10000-PEG2000-ALK | / | Unkown | |
| HY-167864 | M4K2308 | Inhibitor | / | Unkown |
| HY-168163 | CDK12/13 ligand 1 | Degrader | / | Unkown |
| HY-168513 | ALK-IN-29 | Inhibitor | / | Unkown |
| HY-168551 | PROTAC ALK degrader-3 | / | Unkown | |
| HY-168552 | 3-Hydroxyazetidine-Cyclohexanol | / | Unkown | |
| HY-168553 | 3-Hydroxyazetidine-Cyclohexanol-5-Aminothalidomide | / | Unkown | |
| HY-168607 | ALK5-IN-83 | Inhibitor | / | Unkown |
| HY-170418 | ALK/ROS1-IN-5 | / | Unkown | |
| HY-170592 | dALK-3 | Degrader | / | Unkown |
| HY-171825 | SIAIS001 | Degrader | / | Unkown |
| HY-172426 | Dirozalkib | Inhibitor | / | Unkown |
| HY-172958 | F6524-1593 | Inhibitor | / | Unkown |
| HY-173007 | ALK/PI3K/AKT-IN-1 | / | Unkown | |
| HY-173493 | ALK-IN-31 | / | Unkown | |
| HY-174314 | WZH-15-125 | Inhibitor | / | Unkown |
| HY-174315 | WZH-17-002 | / | Unkown | |
| HY-174368 | PROTAC EML4-ALK Degrader-1 | / | Unkown | |
| HY-175271 | JWJ-01-378 | / | Unkown | |
| HY-175527 | ALK degrader 2 | / | Unkown | |
| HY-175528 | ALK ligand-Linker Conjugate 1 | / | Unkown | |
| HY-175849 | ALK degrader 1 | / | Unkown | |
| HY-17603A | (E)-Belizatinib | Inhibitor | / | Unkown |
| HY-17661 | Depiperazine-DM3189 | Inhibitor | / | Unkown |
| HY-176941 | ALK2-IN-6 | Inhibitor | / | Unkown |
| HY-177945 | MS99-β-Gal | Degrader | / | Unkown |
| HY-178057 | EGFR-IN-176 | / | Unkown | |
| HY-178231 | ALK5-IN-85 | Inhibitor | / | Unkown |
| HY-178391 | SMU-037 | / | Unkown | |
| HY-179732 | PROTAC ALK degrader-4 | / | Unkown | |
| HY-179733 | CRBN ligand-191 | / | Unkown | |
| HY-179735 | CRBN ligand-192 | / | Unkown | |
| HY-18030B | CEP-28122 mesylate hydrochloride | Inhibitor | / | Unkown |
| HY-180811 | ALK/HDAC-IN-2 | / | Unkown | |
| HY-180818 | ALK-IN-33 | / | Unkown | |
| HY-180956 | PROTAC ALK degrader-5 | / | Unkown | |
| HY-180964 | Lys-PEG3-BA | Degrader | / | Unkown |
| HY-180965 | Pro-PEG3-BA | / | Unkown | |
| HY-180966 | Gly-PEG3-BA | Degrader | / | Unkown |
| HY-180972 | PROTAC EML4-ALK Degrader-2 | Inhibitor | / | Unkown |
| HY-181113 | ALK-IN-34 | Inhibitor | / | Unkown |
| HY-181139 | ALK5-IN-86 | Inhibitor | / | Unkown |
| HY-182057 | ALK degrader 4 | Degrader | / | Unkown |
| HY-182087 | ALK degrader 3 | Degrader | / | Unkown |
| HY-182547 | LY580276 | Inhibitor | / | Unkown |
| HY-183358 | ALK-IN-37 | / | Unkown | |
| HY-183440 | Amine-C2-piperazine-C4-OH | / | Unkown | |
| HY-183441 | ALK5 ligand-1 | Ligand | / | Unkown |
| HY-183442 | ALK5 ligand-1-amine-C2-piperazine-C4-OH | Ligand | / | Unkown |
| HY-183717 | M4K3233 | / | Unkown | |
| HY-183718 | M4K3250 | Degrader | / | Unkown |
| HY-183767 | Aurora kinase/ALK-IN-1 | / | Unkown | |
| HY-183785 | PROTAC ALK5 Degrader-1 | Degrader | / | Unkown |
| HY-183950 | ALK5-IN-87 | Inhibitor | / | Unkown |
| HY-184652 | LRRK2/JNK3-IN-1 | Inhibitor | / | Unkown |
| HY-185430 | HM-279 | Inhibitor | / | Unkown |
| HY-50878AS | Crizotinib-d9 hydrochloride | / | Unkown | |
| HY-E70642 | ALK C1156Y Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70643 | ALK F1174L Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70644 | ALK F1174S Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70645 | ALK G1202R Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70646 | ALK L1196M Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70647 | ALK R1275Q Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70713 | EML4 ALK Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70714 | EML4 ALK F1174L Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70760 | NPM1 ALK Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70761 | NPM1 ALK F1174L Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-P11354 | THR-123 | / | Unkown | |
| HY-RS00599 | Alk Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS00600 | ALK Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-W1139353 | Tetraasterane | / | Unkown | |
| HY-W707119 | RepSox hydrochloride | Inhibitor | / | Unkown |
| HY-W754809 | ALK ligand-1 | Ligand | / | Unkown |
| HY-107386 | PF-03671148 | Inhibitor | / | Unkown |
| HY-118528 | TP0427736 | Inhibitor | / | Unkown |
| HY-12071BR | LDN193189 dihydrochloride (Standard) | Inhibitor | / | Unkown |
| HY-12857S2 | Brigatinib-d11 | Inhibitor | / | Unkown |
| HY-14243 | CEP-14083 | Inhibitor | / | Unkown |
| HY-149591A | M4K2009 hydrochloride | Inhibitor | / | Unkown |
| HY-158905 | MTDB-Alkyne | Degrader | / | Unkown |
| HY-160172 | ALK/ROS1-IN-4 | Inhibitor | / | Unkown |
| HY-160172A | ALK/ROS1-IN-4 hydrate | Inhibitor | / | Unkown |
| HY-162902 | ALK5-IN-82 | Inhibitor | / | Unkown |
| HY-179400 | LDN-193688 | Inhibitor | / | Unkown |
| HY-184317 | M4K2149 | Inhibitor | / | Unkown |
| HY-50878S1 | Crizotinib-d8 | / | Unkown | |
| HY-50878S2 | Crizotinib-d9 | / | Unkown | |
| HY-W814315 | Alectinib analog | / | Unkown |
Inhibitory Antibodies
(4)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P992188 | Anti-ALK7 Antibody | / | Unkown | |
| HY-P991533 | DLX-521 | Inhibitor | / | Unkown |
| HY-P991855 | RKER-216 | Inhibitor | / | Unkown |
| HY-P991862 | CDX-0125-TEI Antibody | / | Unkown |
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