220 Results for "

Cyclo(-RGDfK) TFA

" in MedChemExpress (MCE) Product Catalog:
Products (220)

220 Results for "Cyclo(-RGDfK) TFA" in MCE Product Catalog:

Iturin A-2
Iturin A-2
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製品番号: HY-P10785
CAS 番号: 83785-07-3
Target:  

Bacterial Antibiotic

研究分野:  

Infection

Iturin A-2 is a cyclic lipopeptide discovered in B. subtilis and exhibits inhibitory activity against the plant pathogenic fungus P. expansum (MIC = 8 µg/disk). Iturin A-2 is cytotoxic to MCF-7 and BT474 breast cancer cells, as well as HeLa cervical cancer cells, with IC50 values of 66.81, 95.04, and 77.5 µg/mL, respectively. In greenhouse studies, Iturin A-2 at concentrations of 100 and 300 mg/kg Iturin A-2 reduces the lesion area of southern corn leaf blight caused by B. maydis, and in field studies, concentrations of 300 and 500 mg/kg Iturin A-2 reduce the incidence of the disease. Iturin A-2 (12.5 µg/mL) inhibits cell division, but not nuclear division, in isolated fertilized starfish eggs .
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GPC3 targeting peptide 1
GPC3 targeting peptide 1
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製品番号: HY-P10888
CAS 番号: 3066113-41-2
Target:  

Glycoprotein VI

研究分野:  

Cancer

GPC3 targeting peptide 1 is a GPC3 targeting peptide, with a Kd value of 0.23 nM .
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GPC3 targeting peptide 1 TFA
GPC3 targeting peptide 1 TFA
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製品番号: HY-P10888A
Target:  

Glycoprotein VI

研究分野:  

Cancer

GPC3 targeting peptide 1 TFA is a GPC3 targeting peptide, with a Kd value of 0.23 nM .
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CyLip-20
CyLip-20
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製品番号: HY-P11582
Target:  

Bacterial

研究分野:  

Infection

CyLip-20 is a cyclic lipopeptide antimicrobial peptide that targets Gram-positive and Gram-negative bacteria. CyLip-20 exhibits low hemolytic activity and mild in vivo toxicity. CyLip-20 disrupts the integrity of bacterial outer membrane, inner membrane and cytoplasmic membrane by binding to bacterial lipopolysaccharide (LPS), triggering membrane permeabilization, depolarization and leakage of intracellular contents, and inhibits bacterial biofilm formation. In animal models, CyLip-20 reduces the bacterial load in skin wounds of mice infected with MRSA, promotes wound healing, decreases the levels of inflammatory cytokines and reduces inflammatory cell infiltration. CyLip-20 can be used in research related to MRSA skin wound infections .
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Aspartocin D
Aspartocin D
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製品番号: HY-P2070
CAS 番号: 1211953-97-7
Target:  

Bacterial

研究分野:  

Infection

Aspartocin D is an analogue of Amphomycin (HY-P3078). Aspartocin D shows antimicrobial activities against Gram-positive bacteria .
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ADA2
ADA2
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製品番号: HY-P11846
Target:  

ADAMTS

研究分野:  

Cardiovascular Disease

ADA2 is an ADAMTS4-binding peptide and imaging agent with a human ADAMTS4 Ka of 5.3 nM and reduced renal uptake compared to related tracers. ADA2 accumulates in dilated aortic regions in aortic aneurysm mouse models. ADA2 exhibits an in vivo safety profile. ADA2 can be used for the research of aortic aneurysm .
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FM213
FM213
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製品番号: HY-P11891
Target:  

PD-1/PD-L1

研究分野:  

Cancer

FM213 is a PD-L1 inhibitor with a human IC50 of 323 nM. FM213 blocks PD-1/PD-L1 protein-protein interactions, and promotes endocytosis and lysosome-dependent degradation of PD-L1 on the surface of cancer cells. FM213 binds to PD-L1 on cancer cells and exosomes, and enhances the recognition and killing of cancer cells by human PBMC. Combination of FM213 with the TIGIT inhibitor DTBP-3 (HY-P11903) enhances anti-tumor immunity. FM213 can be used in research related to non-small cell lung cancer .
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tP4-CPP12
tP4-CPP12
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製品番号: HY-P11841
Target:  

DNA/RNA Synthesis

研究分野:  

Cancer

tP4-CPP12 is a RMI1/2 heterodimer inhibitor with an IC50 of 110 nM. tP4-CPP12 binds competitively at the FANCM-RMI interaction site and disrupts endogenous FANCM-RMI protein-protein interactions. tP4-CPP12 induces antiproliferative effects in ALT-positive osteosarcoma cells. tP4-CPP12 is applicable for the research of ALT-positive osteosarcoma .
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Nummularine B
Nummularine B
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製品番号: HY-P2209
CAS 番号: 53947-96-9
別名: Daechuine S27; N-Demethylamphibine H
Category:  

Alkaloids Other Alkaloids Plants Actaea simplex (DC.) Wormsk. ex Fisch. & C. A. Mey. Rhamnaceae

Target:  

Parasite Phosphodiesterase (PDE)

Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC50 of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca 2+-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis .
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Mycobacillin
Mycobacillin
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製品番号: HY-N14799
CAS 番号: 18524-67-9
Category:  

Microorganisms Antibiotics Other Antibiotics

Target:  

Antibiotic Fungal

Mycobacillin is a peptide antibiotic with anti-antifungal activity .
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Mp-4D7-pF2
Mp-4D7-pF2
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製品番号: HY-P11032
CAS 番号: 3106022-48-1
Target:  

SARS-CoV Virus Protease

研究分野:  

Infection

Mp-4D7-pF2, a cell-penetrating bicyclic peptide, is a noncovalent SARS-CoV-2 main protease inhibitor with an IC50 of 4.51 μM. Mp-4D7-pF2 has an antiviral activity against SARS-CoV-2 with no cytotoxicity. Mp-4D7-pF2 can used for COVID-19 infections research .
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TATE-DA-I
TATE-DA-I
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製品番号: HY-P11924
Target:  

Somatostatin Receptor Drug Intermediate

研究分野:  

Cancer

TATE-DA-I is a somatostatin receptor 2 (SSTR2) ligand with an IC50 of 25.3 nM. TATE-DA-I binds to albumin to prolong its circulation retention time and also exhibits enhanced tumor accumulation capacity. TATE-DA-I enables clear visualization of SSTR2-positive tumors in SPECT/CT imaging. TATE-DA-I can be used in cancer-related research .
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TAK 044
TAK 044
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製品番号: HY-105168
CAS 番号: 157380-72-8
Target:  

Endothelin Receptor

研究分野:  

Cardiovascular Disease

TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
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JR11-PEG3-DOTA-PSMA-03
JR11-PEG3-DOTA-PSMA-03
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製品番号: HY-P11488
Target:  

Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor PSMA

研究分野:  

Cancer

JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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JR11-PEG3-HBED-CC-PSMA-03
JR11-PEG3-HBED-CC-PSMA-03
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製品番号: HY-P11485
Target:  

Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor PSMA

研究分野:  

Cancer

JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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Ternatin
Ternatin
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製品番号: HY-125357
CAS 番号: 148619-41-4
Target:  

阻害性抗体

研究分野:  

Metabolic Disease

Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC50 of 0.027 μM in 3T3-L1 adipocytes .
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Omphalotin A
Omphalotin A
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製品番号: HY-P5957
CAS 番号: 186511-50-2
Category:  

Microorganisms Cyclopeptides

Target:  

Parasite

Omphalotin A is a cyclic peptide, and shows nematicidal activity .
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WL12
WL12
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製品番号: HY-P3440
CAS 番号: 1886057-64-2
Target:  

Radionuclide-Drug Conjugates (RDCs) PD-1/PD-L1

研究分野:  

Cancer

WL12 is a specifically targeting programmed death ligand 1 (PD-L1) binding peptide. WL12 can be radiolabeled by different radionuclides, generating radiotracers, which can assess the tumor PD-L1 expression .
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BiS3
BiS3
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製品番号: HY-P11927
Target:  

GSK-3

研究分野:  

Cancer

BiS3 is a selective hyperbivalent macrocyclic peptide GSK3β inhibitor, with a Kd of 0.28 nM and an IC50 of 4.8 nM against GSK3β. BiS3 is applicable to studies related to GSK3β signaling and colorectal cancer .
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Coumarin-Phalloidin
Coumarin-Phalloidin
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製品番号: HY-P4948
CAS 番号: 1926163-49-6
Target:  

Biochemical Assay Reagents

研究分野:  

Others

Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .
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Assay Types