Cp - ceruloplasmin Gene

Also Known as CERP

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24268

Summary

Enables copper ion binding activity. Involved in several processes, including female pregnancy; gland development; and response to copper ion. Located in extracellular space. Is anchored component of plasma membrane. Used to study brain edema and iron metabolism disease. Biomarker of Wilson disease; brain ischemia; heart disease; and hyperthyroidism. Human ortholog(s) of this gene implicated in aceruloplasminemia; epilepsy; and hemosiderosis. Orthologous to human CP (ceruloplasmin). [provided by Alliance of Genome Resources, Apr 2022]

Cp Products (2)

mRNA Protein Name
NM_001270961.1 NP_001257890.1 ceruloplasmin isoform 2 precursor
NM_012532.2 NP_036664.2 ceruloplasmin isoform 1 precursor
Molecular Function GO Annotation Evidence References Source
enables copper ion binding IDA
IDA: Inferred from direct assay
12099680 RGD
Biological Process GO Annotation Evidence References Source
involved in female pregnancy IEP
IEP: Inferred from expression pattern
28089327 RGD
involved in lactation IEP
IEP: Inferred from expression pattern
28089327 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
2332446 RGD
involved in lung development IEP
IEP: Inferred from expression pattern
2332446 RGD
involved in mammary gland involution IEP
IEP: Inferred from expression pattern
28089327 RGD
involved in response to copper ion IDA
IDA: Inferred from direct assay
19700037 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
16597684 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
10660599 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
10660599 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ceruloplasmin

  • bilitranslocase

  • ceruloplasmin (ferroxidase)

Orthologs Information

Species Symbol Source ID
Homo sapiens Cp NCBI NCBI:1356