1 Result for "

2'-Acetylacteoside (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2'-Acetylacteoside (Standard)" in MCE Product Catalog:

2'-Acetylacteoside (Standard)
2'-Acetylacteoside (Standard)
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Cat. No.: HY-N0026R
CAS No.: 94492-24-7
Synonyms: 2'-AA (Standard)
Category:  

Simple Phenylpropanols Scrophulariaceae Extract Phenylpropanoids Plants Brandisia hancei Hook. f.

Target:  

Reference Standards Monoamine Oxidase RANKL/RANK TNF Receptor NF-κB IKK

2'-Acetylacteoside (Standard) is the analytical standard of 2'-Acetylacteoside (2'-AA) (HY-N0026). This product is intended for research and analytical applications. 2'-Acetylacteoside is a natural compound with oral activity and blood-brain barrier permeability. 2'-Acetylacteosideexhibits MAO‑B inhibitory activity (IC50 = 17.71 μM, Ki = 13.81 μM). 2'-Acetylacteoside downregulates the expression of RANK, TRAF6, NF‑κB, NFATc1 and IKKβ, disrupts the RANKL/RANK interaction, blocks downstream signaling pathways, and increases the level of phosphorylated Akt. 2'-Acetylacteoside possesses potent anti-osteoclastogenic, anti-bone resorptive, pro-neurogenic, neuroprotective and antioxidant activities. 2'-Acetylacteoside can be used in the research of osteoporosis, ischemic stroke and Parkinson's disease .
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