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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
222 Results for "
Cyclo(-RGDfK)
" in MedChemExpress (MCE) Product Catalog:
Products (222)
222 Results for "Cyclo(-RGDfK)" in MCE Product Catalog:
Cat. No.: HY-P11752
Cat. No.: HY-P11853
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cRY9M is a cyclic peptide that binds to FGFR1, with a KD value of 58 nM. cRY9M binds specifically to FGFR1, exhibits enhanced in vivo stability, and shows extremely low degradation in blood, urine and liver homogenate after injection. cRY9M displays significant specific uptake in FGFR1-positive tumor xenograft models, while its uptake decreases in FGFR1-negative tumor models and blocking models. The NOTA-chelated precursor of cRY9M can be labeled with 68Ga to obtain [ 68Ga]Ga-NOTA-cRY9M, which is used for research on non-invasive imaging of FGFR1 expression in non-small cell lung cancer .
Cat. No.: HY-P11853A
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cRY9M acetate is a cyclic peptide that binds to FGFR1, with a KD value of 58 nM. cRY9M acetate binds specifically to FGFR1, exhibits enhanced in vivo stability, and shows extremely low degradation in blood, urine and liver homogenate after injection. cRY9M acetate displays significant specific uptake in FGFR1-positive tumor xenograft models, while its uptake decreases in FGFR1-negative tumor models and blocking models. The NOTA-chelated precursor of cRY9M acetate can be labeled with 68Ga to obtain [ 68Ga]Ga-NOTA-cRY9M, which is used for research on non-invasive imaging of FGFR1 expression in non-small cell lung cancer .
Cat. No.: HY-P12217
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Cyclic MC4R peptide agonist-1 is a cyclic peptide agonist of the melanocortin-4 receptor (melanocortin-4 receptor). Cyclic MC4R peptide agonist-1 activates the human melanocortin-4 receptor via an alternative activation motif centered on APWR, and this activation process is independent of the classical HFRW pharmacophore. Cyclic MC4R peptide agonist-1 inhibits signal transduction of the human melanocortin-3 receptor and melanocortin-5 receptor. Cyclic MC4R peptide agonist-1 is used in research related to obesity .
Cat. No.: HY-P10304D
Cat. No.: HY-P11751A
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Cat. No.: HY-P11626
CAS No.: 67943-21-9
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Cat. No.: HY-P11627
CAS No.: 36099-80-6
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Cat. No.: HY-P11813
CAS No.: 160662-30-6
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Cat. No.: HY-P2044
CAS No.: 585535-37-1
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Cat. No.: HY-P11757
CAS No.: 2251785-27-8
Cat. No.: HY-P11773
CAS No.: 1094848-94-8
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Cat. No.: HY-P11899
Synonyms: Cyclo(VVIaWG)
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Cyclo (Val-Val-Ile-d-Ala-Trp-Gly) (Cyclo(VVIaWG)) is a six-membered cyclic peptide designed based on the C-terminal region of Aβ1-42. Cyclo (Val-Val-Ile-d-Ala-Trp-Gly) binds selectively to Aβ15-36 (Kd = 0.6 μM), regulates the aggregation of Aβ1-42 at high concentrations, weakly inhibits fibrillation at a 10-fold excess, and inhibits oligomerization at equimolar concentrations. Cyclo (Val-Val-Ile-d-Ala-Trp-Gly) does not interfere with the aggregation of IAPP. Cyclo (Val-Val-Ile-d-Ala-Trp-Gly) can serve as a targeting ligand for fluorescent probes of Aβ prefibrillar aggregates, and is applicable to research related to Alzheimer's disease .
Cat. No.: HY-P1613
CAS No.: 137813-35-5
Synonyms: Cyclo(RGDfV); C(RGDfV)
Cat. No.: HY-P1613A
CAS No.: 199807-33-5
Synonyms: Cyclo(RGDfV) TFA; C(RGDfV) TFA
Cat. No.: HY-P2306
CAS No.: 1055991-02-0
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Cat. No.: HY-P3557
CAS No.: 1239011-83-6
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Cat. No.: HY-P3557A
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Cat. No.: HY-P4907
CAS No.: 756500-24-0
Cat. No.: HY-P5021
CAS No.: 756500-22-8
Synonyms: c(RGDfE)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
