7 Results for "

(+)-Evodiamine

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "(+)-Evodiamine" in MCE Product Catalog:

20
20 Cited Publications
Cat. No.: HY-N0114
CAS No.: 518-17-2
Synonyms: (+)-Evodiamine; d-Evodiamine
Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N0114A
CAS No.: 518-18-3
(±)-Evodiamine is an orally active indoloquinazoline alkaloid composed of equal amounts of enantiomers, with (+)-Evodiamine exerting the primary biological functions. (±)-Evodiamine is a Top1 inhibitor and a TRPV1 receptor agonist. (±)-Evodiamine induces cell cycle arrest and apoptosis by inhibiting Top1 and disrupting Tubulin polymerization, suppresses oncogenic signaling pathways such as NF-κB and Akt, and specifically agonizes TRPV1 receptors to regulate neuropeptide release and energy metabolism. (±)-Evodiamine is used in research on traumatic brain injury, obesity, cancer, neuropathy, dry eye disease, and colitis .
loading...
    loading...
Cat. No.: HY-161501
Research Areas:  

Cancer

3-Fluoro-evodiamine glucose (Compound 8) is an evodiamine-glucose conjugate. 3-Fluoro-evodiamine glucose activates the expression of glucose transporter 1 (GLUT1), and inhibits topoisomerase I/II. 3-Fluoro-evodiamine glucose induces apoptosis and arrests the cell cycle at G2/M phase. 3-Fluoro-evodiamine glucose exhibits antitumor efficacy in vivo and in vitro, without significant toxicity .
loading...
    loading...
Cat. No.: HY-N0114R
CAS No.: 518-17-2
Synonyms: (+)-Evodiamine (Standard); d-Evodiamine (Standard)
Evodiamine (Standard) is the analytical standard of Evodiamine. This product is intended for research and analytical applications. Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor.
loading...
    loading...
Cat. No.: HY-N0114AR
CAS No.: 518-18-3
(±)-Evodiamine Standard is the analytical standard of (±)-Evodiamine (HY-N0114A). This product is intended for research and analytical applications. (±)-Evodiamine is an orally active indoloquinazoline alkaloid composed of equal amounts of enantiomers, with (+)-Evodiamine exerting the primary biological functions. (±)-Evodiamine is a Top1 inhibitor and a TRPV1 receptor agonist. (±)-Evodiamine induces cell cycle arrest and apoptosis by inhibiting Top1 and disrupting Tubulin polymerization, suppresses oncogenic signaling pathways such as NF-κB and Akt, and specifically agonizes TRPV1 receptors to regulate neuropeptide release and energy metabolism. (±)-Evodiamine is used in research on traumatic brain injury, obesity, cancer, neuropathy, dry eye disease, and colitis .
loading...
    loading...
Cat. No.: HY-168736
CAS No.: 3023350-74-2
Target:  

Drug Derivative

Research Areas:  

Cancer

CRC-IN-1 (compound (-)-15h) is a potent anti-colorectal cancer (CRC) agent, as well as a derivative of the anticancer agent Evodiamine (HY-N0114) .
loading...
    loading...
Cat. No.: HY-N18094
CAS No.: 116965-70-9
Evodiamide is a new alkaloid found in the dried fruits of Evodia rutaecarpa (Rutaceae). Evodiamide acts as a proposed precursor in the biosynthesis of evodiamine .
loading...
    loading...