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Results for "

2'-Deoxyuridine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (4) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (2) DNA Methyltransferase (1) DNA Stain (1) DNA/RNA Synthesis (15) Drug Metabolite (5) Endogenous Metabolite (18) Fluorescent Dye (1) HCV (1) HSV (2) Isotope-Labeled Compounds (12) Nucleoside Antimetabolite/Analog (36) Orthopoxvirus (2) Phosphatase (3) Phosphoramidites (3) PROTAC Linkers (3) Reference Standards (8) Somatostatin Receptor (1) Thymidylate Synthase (6)
By Research Areas:	Cancer (44) Cardiovascular Disease (1) Endocrinology (1) Infection (25) Inflammation/Immunology (1) Metabolic Disease (7) Neurological Disease (2)
Click Chemistry:	PROTAC Synthesis (1) Azide (7) Alkynes (4)
Oligonucleotides:	Nucleoside Analogs (31) Nucleotide Analogs (3) Uridine (30) Uracil Nucleotide (1) Uracil (3) Phosphoramidites (3)

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Fluorescent Dyes

Biochemical Assay Reagents

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Isotope-Labeled Compounds

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Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-118411

5-Ethynyl-2'-deoxyuridine 30+ Cited Publications EdU	PROTAC Linkers	Cancer
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-15910

5-BrdU 75+ Cited Publications BrdU; 5-Bromo-2'-Deoxyuridine; BUdR	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Cancer
5-BrdU (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells.

HY-17365

Octreotide acetate 15+ Cited Publications SMS 201-995 acetate	Somatostatin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.

HY-B0307

Idoxuridine 5+ Cited Publications 5-Iodo-2′-Deoxyuridine; 5-IUdR; IdUrd	DNA/RNA Synthesis Phosphatase Orthopoxvirus	Infection Cancer
Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC₅₀ value of 4.3 μM . Idoxuridine shows anti-orthopoxvirus activity.

HY-112669

5-Chloro-2'-deoxyuridine 4 Publications Verification 5-ChloroDeoxyuridine; CldU	Nucleoside Antimetabolite/Analog	Neurological Disease
5-Chloro-2'-deoxyuridine, a thymine analog, is to study the potential of hypochlorous acid damage to DNA and DNA precursors.

HY-D0186

2'-Deoxyuridine 3 Publications Verification	Endogenous Metabolite Thymidylate Synthase	Infection
2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) .

HY-138253

2′,2′-Difluorodeoxyuridine dFdU; 2',2'-Difluoro-2'-Deoxyuridine	Drug Metabolite Apoptosis	Cancer
2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells .

HY-129983

5-Hydroxymethyl-2'-deoxyuridine	HSV	Infection Cancer
5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analog. 5-Hydroxymethyl-2'-deoxyuridine inhibits the replication of multiple human leukemia cell lines with IC₅₀ values of 1.7-5.8 μM. 5-Hydroxymethyl-2'-deoxyuridine prolongs the survival of mice carrying L1210 leukemia. 5-Hydroxymethyl-2'-deoxyuridine can be used for the research of cell replication and leukemia .

HY-13420

Zebularine 5 Publications Verification NSC309132; 4-Deoxyuridine	DNA Methyltransferase Autophagy	Cancer
Zebularine (NSC309132; 4-Deoxyuridine) is a DNA methyltransferase inhibitor. Zebularine also inhibits cytidine deaminase with a K_i of 0.95 μM.

HY-W011142

*2'-Deoxyuridine* 5'-monophosphate disodium** dUMP disodium	Endogenous Metabolite	Infection Metabolic Disease
2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .

HY-W017068

dUTP trisodium 2'-Deoxyuridine-5'-triphosphate trisodium salt	DNA/RNA Synthesis	Others
dUTP trisodium (2´-Deoxyuridine, 5´-Triphosphate) is the salt form of dUTP. dUTP is a metabolic intermediate in both procaryotes and eucaryotes. dUTP can be used in PCR and RT-PCR to replace dTTP, resulting in the uracil-containing PCR products suitable for most standard applications. dUTP is found to inhibit the enzyme - Cytidine Aminohydrolase from sheep liver .

HY-B0021

Doxifluridine 2 Publications Verification Ro 21-9738; 5-Fluoro-5'-Deoxyuridine; 5'-DFUR	Thymidylate Synthase	Cancer
Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .

HY-W012282

3′-Deoxyuridine	HCV	Infection
3′-Deoxyuridine is a 3'-deoxynucleoside analog and a 2',3'-dideoxynucleoside. 3′-Deoxyuridine does not inhibit the replication of HCV-like RNA templates or luciferase levels in human cells at the tested concentrations. 3′-Deoxyuridine serves as a substrate for microbial dideoxyribosylation reactions to generate various 2',3'-dideoxynucleosides, but cannot be converted into 2',3'-dideoxycytidine by resting E. coli AJ 2595 cells. 3′-Deoxyuridine can be formed by the deamination of 3'-deoxycytidine by E. coli BM-11 cytidine deaminase, and can also undergo phosphorolytic cleavage to produce uracil and the corresponding pentose phosphate. 3′-Deoxyuridine has been used in research related to HCV and other relevant fields .

HY-48873

*5'-O-DMT-5-Ethynyl-2'-deoxyuridine* 3'-CE phosphoramidite**	DNA/RNA Synthesis Phosphoramidites	Others
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-138253R

2′,2′-Difluorodeoxyuridine (Standard) dFdU (Standard); 2',2'-Difluoro-2'-Deoxyuridine (Standard)	Drug Metabolite Reference Standards Apoptosis	Cancer
2′,2′-Difluorodeoxyuridine (Standard) is the analytical standard of 2′,2′-Difluorodeoxyuridine. This product is intended for research and analytical applications. 2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells.

HY-138253S

2′,2′-Difluorodeoxyuridine-13C,15N2 dFdU-¹³C,¹⁵N₂; 2',2'-Difluoro-2'-Deoxyuridine-¹³C,¹⁵N₂	Isotope-Labeled Compounds Drug Metabolite Apoptosis	Others
2′,2′-Difluorodeoxyuridine- ¹³C, ¹⁵N₂ (dFdU- ¹³C, ¹⁵N₂) is a ¹³C- and ¹⁵N-labeled compound. 2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells .

HY-135780A

*3'-Deoxyuridine-5'-triphosphate trisodium* 3'-dUTP trisodium	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a K_i value of 2.0 μM .

HY-W017068B

dUTP trisodium,100 mM Solution,PCR Grade 2'-Deoxyuridine-5'-triphosphate trisodium,100 mM Solution,PCR Grade	Biochemical Assay Reagents	Others
dUTP trisodium,100 mM Solution,PCR Grade (2'-Deoxyuridine-5'-triphosphate trisodium,100 mM Solution,PCR Grade) is a highly stable nucleotide that can participate in the biosynthesis of DNA and is suitable for various conventional molecular biology experiments. This product is provided in the form of aqueous solution .

HY-W424779

5-Carboxy-2′-deoxyuridine	Drug Metabolite	Infection
5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine . 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine .

HY-W341499

5-Formyl-2'-deoxyuridine	Endogenous Metabolite	Others
5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein .

HY-130801

5-Hydroxy-2'-deoxyuridine 5-OHdU	Endogenous Metabolite	Metabolic Disease
5-Hydroxy-2'-deoxyuridine (5-OHdU) is a major stable oxidation product of 2'-Deoxycytidine. 5-Hydroxy-2'-deoxyuridine can be incorporated into DNA in vitro by DNA polymerase .

HY-W190976

5-Vinyl-2'-deoxyuridine 5-VINYL-DURD	DNA/RNA Synthesis Apoptosis	Cancer
5-Vinyl-2'-deoxyuridine (5-VINYL-DURD), a thymidine analogue, is incorporated into cellular DNA during DNA replication. 5-Vinyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and induces DNA damage leads to apoptosis in human cultured cells .

HY-154253

5-Azidomethyl-2'-deoxyuridine 5-AmdU; α-Azidothymidine	Nucleoside Antimetabolite/Analog	Cancer
5-Azidomethyl-2'-deoxyuridine (5-AmdU) is a purine nucleoside analog. 5-Azidomethyl-2'-deoxyuridine demonstrates effective radiosensitization in EMT6 tumor cells. . 5-Azidomethyl-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W251781

4-Thio-2’-deoxyuridine 2′-Deoxy-4-thiouridine; 4-ThioDeoxyuridine	Nucleoside Antimetabolite/Analog	Cancer
4-Thio-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-D1022A

Biotin-16-dUTP trisodium Biotin-16-Deoxyuridine-5'-triphosphate trisodium	DNA Stain	Others
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-152720

3’-Azido-3’-deoxyuridine	Nucleoside Antimetabolite/Analog	Others Cancer
3’-Azido-3’-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-D1022

Biotin-16-dUTP Biotin-16-Deoxyuridine-5'-triphosphate	Fluorescent Dye	Others
Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-D1023

5-BrdUTP sodium salt 5-Bromo-2'-Deoxyuridine 5'-triphosphate sodium salt	DNA/RNA Synthesis	Others
5-BrdUTP sodium salt is a TdT substrate which can be used to label the DNA double-strand breaks.

HY-D0186R

*2'-Deoxyuridine* (Standard)**	Reference Standards Endogenous Metabolite Thymidylate Synthase	Infection
2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine. This product is intended for research and analytical applications. 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) . In Vitro:The interaction between the 2-deoxyuridine and the column increases the duration of retention of 2-deoxyuridine . Gradient elution with sodium acetate buffer-ACN eluent on two ZIC-HILIC homemade columns separates 2-deoxyuridine in under 9 min . In Vivo:2'-Deoxyuridine (34.42 ng/mL, gavage, 15 min) passes the blood-brain barrier (BBB) to enter the hippocampus of mice brain . 2'-Deoxyuridine (20 mg/kg, gavage, daily for 4 weeks) improves cognition and memory loss and attenuates the damage to the hippocampus in Aβ25-35-induced mice model .

HY-154329

2-Deoxyuridine	Nucleoside Antimetabolite/Analog	Cancer
2-Deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-135780

*3'-Deoxyuridine-5'-triphosphate* 3'-dUTP	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a K_i value of 2.0 μM .

HY-W154172

2′-Chloro-2′-deoxyuridine	Nucleoside Antimetabolite/Analog	Cancer
2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152548

4’-C-Methyl-4-deoxyuridine	Nucleoside Antimetabolite/Analog	Others
4’-C-Methyl-4-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W553730

2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine	Nucleoside Antimetabolite/Analog	Cancer
2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W141338

2′-Bromo-2′-deoxyuridine 2'-Bromo-2'-deoxy-D-uridine	Nucleoside Antimetabolite/Analog	Cancer
2′-Bromo-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154492

2’,3’-Bis(O-t-butyldimethylsilyl)-4’,5’-didehydro-5’-deoxyuridine	Nucleoside Antimetabolite/Analog	Cancer
2’,3’-Bis(O-t-butyldimethylsilyl)-4’,5’-didehydro-5’-deoxyuridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-77645

4',5'-Didehydro-5'-deoxyuridine 1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)uracil	Nucleoside Antimetabolite/Analog	Cancer
4',5'-Didehydro-5'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W416297

dUDP disodium	Nucleoside Antimetabolite/Analog	Others
dUDP disodium is a nucleotide that plays a crucial role in the synthesis of DNA. dUDP disodium consists of a uracil base, a ribose, and two phosphate groups. dUDP disodium is also a substrate for the deoxyuridine triphosphate nucleotide hydrolase, which catalyzes the conversion of dUDP to dUMP, which is the precursor for dTTP synthesis. dUDP disodium is involved in various biochemical processes and can be used for various biochemical analyses and applications .

HY-P5443

Pyrrhocoricin	Bacterial	Others
Pyrrhocoricin is a biological active peptide. (Antimicrobial activity against Gram-negative bacteria)

HY-D0186S4

*2'-Deoxyuridine-d2*	Isotope-Labeled Compounds Endogenous Metabolite	Infection
2'-Deoxyuridine-d₂ is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud

HY-D0186S7

*2'-Deoxyuridine-13C,15N2*	Endogenous Metabolite	Infection
2'-Deoxyuridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled 2'-Deoxyuridine . 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine .

HY-W250162

dUTP Deoxyuridine triphosphate	DNA/RNA Synthesis	Others
dUTP (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position. Dutp can be used in PCR .

HY-W778990

*2-Deoxyuridine-1,2,3,4,5-13C5*	Isotope-Labeled Compounds Thymidylate Synthase Endogenous Metabolite	Infection
2-Deoxyuridine-1,2,3,4,5- ¹³C₅ is the ¹³C-labeled 2'-Deoxyuridine (HY-D0186). 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) .

HY-135957

2'-Azido-2'-deoxyuridine N3dUrd	DNA/RNA Synthesis	Cancer
2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity . 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W394006

*2'-Deoxyuridine* 5'-monophosphate** dUMP	Endogenous Metabolite	Infection Metabolic Disease
2'-Deoxyuridine 5'-monophosphate (dUMP) is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .

HY-W097792

5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine 5'-O-DMT-dU	DNA/RNA Synthesis	Others
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the K_i higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .

HY-154424

2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine	Nucleoside Antimetabolite/Analog	Cancer
2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W397503

5’-O-DMTr-5-iodo-2’-deoxyuridine 2'-Deoxy-5'-O-DMT-5-iodouridine	Nucleoside Antimetabolite/Analog	Cancer
5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-B0307R

Idoxuridine (Standard) 5-Iodo-2′-Deoxyuridine (Standard); 5-IUdR (Standard); IdUrd (Standard)	Reference Standards Phosphatase Orthopoxvirus	Infection Cancer
Idoxuridine (Standard) is the analytical standard of Idoxuridine. This product is intended for research and analytical applications. Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC₅₀ value of 4.3 μM . Idoxuridine shows anti-orthopoxvirus activity.

HY-D0186S5

*2'-Deoxyuridine-d*	Isotope-Labeled Compounds Endogenous Metabolite	Infection
2'-Deoxyuridine-d is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud <

Cat. No.	Product Name	Type

HY-D1022A

Biotin-16-dUTP trisodium Biotin-16-Deoxyuridine-5'-triphosphate trisodium	Fluorescent Dyes
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-D1022

Biotin-16-dUTP Biotin-16-Deoxyuridine-5'-triphosphate	Fluorescent Dyes
Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .

Cat. No.	Product Name	Type

HY-W017068B

dUTP trisodium,100 mM Solution,PCR Grade 2'-Deoxyuridine-5'-triphosphate trisodium,100 mM Solution,PCR Grade	Biochemical Assay Reagents
dUTP trisodium,100 mM Solution,PCR Grade (2'-Deoxyuridine-5'-triphosphate trisodium,100 mM Solution,PCR Grade) is a highly stable nucleotide that can participate in the biosynthesis of DNA and is suitable for various conventional molecular biology experiments. This product is provided in the form of aqueous solution .

HY-D1023

5-BrdUTP sodium salt 5-Bromo-2'-Deoxyuridine 5'-triphosphate sodium salt	Biochemical Assay Reagents
5-BrdUTP sodium salt is a TdT substrate which can be used to label the DNA double-strand breaks.

HY-W097792

5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine 5'-O-DMT-dU	Biochemical Assay Reagents
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the K_i higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-D0186

2'-Deoxyuridine 3 Publications Verification	Infection Natural Products Immune System Disorder Microorganisms Classification of Application Fields Disease markers Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Thymidylate Synthase
2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) .

HY-W011142

*2'-Deoxyuridine* 5'-monophosphate disodium** dUMP disodium	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .

HY-135780A

*3'-Deoxyuridine-5'-triphosphate trisodium* 3'-dUTP trisodium	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite
3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a K_i value of 2.0 μM .

HY-130801

5-Hydroxy-2'-deoxyuridine 5-OHdU	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
5-Hydroxy-2'-deoxyuridine (5-OHdU) is a major stable oxidation product of 2'-Deoxycytidine. 5-Hydroxy-2'-deoxyuridine can be incorporated into DNA in vitro by DNA polymerase .

HY-D0186R

*2'-Deoxyuridine* (Standard)**	Structural Classification Natural Products Immune System Disorder Microorganisms Disease markers Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Thymidylate Synthase
2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine. This product is intended for research and analytical applications. 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) . In Vitro:The interaction between the 2-deoxyuridine and the column increases the duration of retention of 2-deoxyuridine . Gradient elution with sodium acetate buffer-ACN eluent on two ZIC-HILIC homemade columns separates 2-deoxyuridine in under 9 min . In Vivo:2'-Deoxyuridine (34.42 ng/mL, gavage, 15 min) passes the blood-brain barrier (BBB) to enter the hippocampus of mice brain . 2'-Deoxyuridine (20 mg/kg, gavage, daily for 4 weeks) improves cognition and memory loss and attenuates the damage to the hippocampus in Aβ25-35-induced mice model .

HY-135780

*3'-Deoxyuridine-5'-triphosphate* 3'-dUTP	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a K_i value of 2.0 μM .

HY-W011142R

*2'-Deoxyuridine* 5'-monophosphate disodium (Standard)** dUMP disodium (Standard)	Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
2'-Deoxyuridine 5'-monophosphate (disodium) (Standard) is the analytical standard of 2'-Deoxyuridine 5'-monophosphate (disodium) (HY-W011142). This product is intended for research and analytical applications. 2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .

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HY-P70026

	dUTPase/DUT Protein, Human rHuDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial/DUT; Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial; dUTPase; dUTP Pyrophosphatase; DUT	Human	E. coli
	Deoxyuridine 5'-triphosphate nucleotidohydrolase (DUT) is an essential enzyme of nucleotide metabolism, as DUT hydrolyzes dUTP to dUMP and pyrophosphate, preventing uracil misincorporation into DNA efficiently and provides dUMP for thymidylate biosynthesis. DUT also prevents dimerization of PPAR and retinoid X receptor and is essential for embryonic development as well. dUTPase/DUT Protein, Human is the recombinant human-derived dUTPase/DUT protein, expressed by E. coli , with tag free.

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Cat. No.	Product Name	Chemical Structure

HY-138253S

2′,2′-Difluorodeoxyuridine-13C,15N2

2′,2′-Difluorodeoxyuridine- ¹³C, ¹⁵N₂ (dFdU- ¹³C, ¹⁵N₂) is a ¹³C- and ¹⁵N-labeled compound. 2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells .

HY-D0186S4

*2'-Deoxyuridine-d2*
2'-Deoxyuridine-d₂ is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud

HY-D0186S7

*2'-Deoxyuridine-13C,15N2*
2'-Deoxyuridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled 2'-Deoxyuridine . 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine .

HY-W778990

2-Deoxyuridine-1,2,3,4,5-13C5

2-Deoxyuridine-1,2,3,4,5- ¹³C₅ is the ¹³C-labeled 2'-Deoxyuridine (HY-D0186). 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) .

HY-D0186S5

*2'-Deoxyuridine-d*
2'-Deoxyuridine-d is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud <

HY-D0186S

*2'-Deoxyuridine-1′-13C*
2'-Deoxyuridine-1′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-D0186S3

*2'-Deoxyuridine-5′-13C*
2'-Deoxyuridine-5′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-D0186S2

*2'-Deoxyuridine-3′-13C*
2'-Deoxyuridine-3′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-D0186S1

*2'-Deoxyuridine-2′-13C*
2'-Deoxyuridine-2′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-118411S

5-Ethynyl-2'-deoxyuridine-13C1

5-Ethynyl-2'-deoxyuridine- ¹³C₁ (EdU- ¹³C₁) is the ¹³C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W766241

3,5-Dibenzoate-2,2-difluorouridine-13C,15N2
3,5-Dibenzoate-2,2-difluorouridine- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled 2’,2’-Difluoro-2’-deoxyuridine 3',5'-Dibenzoate (HY-W741490).

HY-B0021S1

Doxifluridine-d3
Doxifluridine-d₃ is deuterated labeled Doxifluridine (HY-B0021). Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .

HY-B0021S

Doxifluridine-d2
Doxifluridine-d₂ is the deuterium labeled Doxifluridine . Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC₅₀ of 0.62 μM.

HY-D0186S8

*2'-Deoxyuridine-d2-1*
2'-Deoxyuridine-d₂-1 is the deuterium labeled 2'-Deoxyuridine . 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine .

HY-118411S1

5-Ethynyl-2'-deoxyuridine-13C2

5-Ethynyl-2'-deoxyuridine- ¹³C₂ (EdU- ¹³C₂) is the ¹³C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Host:	Mouse (2) Rabbit (1)
Reactivity:	Human (1) Species independent (2)
Application:	IHC-P (1) ICC/IF (3) WB (1) FC (1)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86707

	BrdU(Proliferation Marker) Antibody (YA6399) BromoDeoxyuridine; BromoDeoxyuridine; 5-Bromo-2′-Deoxyuridine; 5-BrdU; Proliferation Marker; 5-Bromo-2-Deoxyuridine.	ICC/IF	Species independent
	BrdU(Proliferation Marker) Antibody (YA6399) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to BrdU(Proliferation Marker).

HY-P86707A

	BrdU(Proliferation Marker) Antibody (YA6399)(PBS only) BromoDeoxyuridine; BromoDeoxyuridine; 5-Bromo-2′-Deoxyuridine; 5-BrdU; Proliferation Marker; 5-Bromo-2-Deoxyuridine.	ICC/IF	Species independent
	BrdU(Proliferation Marker) Antibody (YA6399) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to BrdU(Proliferation Marker).

HY-P87153

	dUTPase Antibody (YA6846) Deoxyuridine 5' triphosphate nucleotidohydrolase, nuclear isoform antibody; Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial antibody; Deoxyuridine triphosphatase antibody; dut antibody; DUT_HUMAN antibody; dUTP nucleotidohydrolase antibody; dUTP pyrophosphatase antibody; dUTPase antibody; FLJ20622 antibody;	WB, IHC-P, ICC/IF, FC	Human
	dUTPase Antibody (YA6846) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to dUTPase.

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Cat. No.	Product Name		Classification

HY-118411

5-Ethynyl-2'-deoxyuridine 30+ Cited Publications EdU		PROTAC Synthesis Alkynes
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154253

5-Azidomethyl-2'-deoxyuridine 5-AmdU; α-Azidothymidine		Azide
5-Azidomethyl-2'-deoxyuridine (5-AmdU) is a purine nucleoside analog. 5-Azidomethyl-2'-deoxyuridine demonstrates effective radiosensitization in EMT6 tumor cells. . 5-Azidomethyl-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152720

3’-Azido-3’-deoxyuridine		Azide
3’-Azido-3’-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-135957

2'-Azido-2'-deoxyuridine N3dUrd		Azide
2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity . 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154405

5’-Azido-5’-deoxyuridine		Azide
5’-Azido-5’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 5’-Azido-5’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154143

3’-Beta-C-Ethynyl-4-deoxyuridine		Alkynes
3’-Beta-C-Ethynyl-4-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Beta-C-Ethynyl-4-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-118411S

*5-Ethynyl-2'-deoxyuridine-13C1* EdU-¹³C		Alkynes
5-Ethynyl-2'-deoxyuridine- ¹³C₁ (EdU- ¹³C₁) is the ¹³C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154423

2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine		Azide
2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154334

2’-O-Acetyl-3’-azido-5’-O-(4-methylbenzoyl)-3’-deoxyuridine		Azide
2’-O-Acetyl-3’-azido-5’-O-(4-methylbenzoyl)-3’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2’-O-Acetyl-3’-azido-5’-O-(4-methylbenzoyl)-3’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152985

3’-Azido-3’-deoxy-4-deoxyuridine		Azide
6-Chloro-N1-(trimethylsilylethoxymethyl)pseudouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 3’-Azido-3’-deoxy-4-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-118411S1

*5-Ethynyl-2'-deoxyuridine-13C2* EdU-¹³C₂		Alkynes
5-Ethynyl-2'-deoxyuridine- ¹³C₂ (EdU- ¹³C₂) is the ¹³C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-15910

5-BrdU 75+ Cited Publications BrdU; 5-Bromo-2'-Deoxyuridine; BUdR		Nucleoside Analogs Uridine
5-BrdU (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells.

HY-W011142

*2'-Deoxyuridine* 5'-monophosphate disodium** dUMP disodium		Nucleotide Analogs
2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .

HY-48873

*5'-O-DMT-5-Ethynyl-2'-deoxyuridine* 3'-CE phosphoramidite**		Phosphoramidites Uracil
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W424779

5-Carboxy-2′-deoxyuridine		Nucleoside Analogs Uridine
5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine . 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine .

HY-W341499

5-Formyl-2'-deoxyuridine		Nucleoside Analogs Uridine
5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein .

HY-154253

5-Azidomethyl-2'-deoxyuridine 5-AmdU; α-Azidothymidine		Nucleoside Analogs Uridine
5-Azidomethyl-2'-deoxyuridine (5-AmdU) is a purine nucleoside analog. 5-Azidomethyl-2'-deoxyuridine demonstrates effective radiosensitization in EMT6 tumor cells. . 5-Azidomethyl-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W251781

4-Thio-2’-deoxyuridine 2′-Deoxy-4-thiouridine; 4-ThioDeoxyuridine		Nucleoside Analogs Uridine
4-Thio-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152720

3’-Azido-3’-deoxyuridine		Nucleoside Analogs Uridine
3’-Azido-3’-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154329

2-Deoxyuridine		Nucleoside Analogs Uridine
2-Deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W154172

2′-Chloro-2′-deoxyuridine		Nucleoside Analogs Uridine
2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152548

4’-C-Methyl-4-deoxyuridine		Nucleoside Analogs Uridine
4’-C-Methyl-4-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W553730

2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine		Nucleoside Analogs Uridine
2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W141338

2′-Bromo-2′-deoxyuridine 2'-Bromo-2'-deoxy-D-uridine		Nucleoside Analogs Uridine
2′-Bromo-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154492

2’,3’-Bis(O-t-butyldimethylsilyl)-4’,5’-didehydro-5’-deoxyuridine		Nucleoside Analogs Uridine
2’,3’-Bis(O-t-butyldimethylsilyl)-4’,5’-didehydro-5’-deoxyuridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-77645

4',5'-Didehydro-5'-deoxyuridine 1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)uracil		Nucleoside Analogs Uridine
4',5'-Didehydro-5'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W394006

*2'-Deoxyuridine* 5'-monophosphate** dUMP		Nucleotide Analogs Uracil Nucleotide
2'-Deoxyuridine 5'-monophosphate (dUMP) is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .

HY-W097792

5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine 5'-O-DMT-dU		Nucleoside Analogs Uridine
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the K_i higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks .

HY-154424

2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine		Nucleoside Analogs Uridine
2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W397503

5’-O-DMTr-5-iodo-2’-deoxyuridine 2'-Deoxy-5'-O-DMT-5-iodouridine		Nucleoside Analogs Uridine
5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154405

5’-Azido-5’-deoxyuridine		Nucleoside Analogs Uridine
5’-Azido-5’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 5’-Azido-5’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154143

3’-Beta-C-Ethynyl-4-deoxyuridine		Nucleoside Analogs Uridine
3’-Beta-C-Ethynyl-4-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Beta-C-Ethynyl-4-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152445

3’-Amino-3’-deoxyuridine		Nucleoside Analogs Uridine
3’-Amino-3’-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154120

6-Aza-2'-deoxyuridine		Nucleoside Analogs Uridine
6-Aza-2'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154533

3’-O-Acetyl-2’-deoxyuridine		Nucleoside Analogs Uridine
3’-O-Acetyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154237

5’-O-DMTr-3’-deoxyuridine		Nucleoside Analogs Uridine
5’-O-DMTr-3’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154239

5’-O-Triphenylmethyl-2’-deoxyuridine		Nucleoside Analogs Uridine
5’-O-Triphenylmethyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154026

*5-Amino-2'-deoxyuridine* monohydrochloride**		Nucleoside Analogs Uridine
5-Amino-2'-deoxyuridine (monohydrochloride) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152715

2’-C-β-Methyl-4-deoxyuridine		Nucleoside Analogs Uridine
2’-C-β-Methyl-4-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152618

3’-N-Acetyl-3’-amino-3’-deoxyuridine		Nucleoside Analogs Uridine
3’-N-Acetyl-3’-amino-3’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154238

*5’-O-DMTr-3’-deoxyuridine* 2’-CED phosphoramidite**		Phosphoramidites Uracil
5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154423

2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine		Nucleoside Analogs Uridine
2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154160

5-(2-Hydroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine		Nucleoside Analogs Uridine
5-(2-Hydroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154334

2’-O-Acetyl-3’-azido-5’-O-(4-methylbenzoyl)-3’-deoxyuridine		Nucleoside Analogs Uridine
2’-O-Acetyl-3’-azido-5’-O-(4-methylbenzoyl)-3’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2’-O-Acetyl-3’-azido-5’-O-(4-methylbenzoyl)-3’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152985

3’-Azido-3’-deoxy-4-deoxyuridine		Nucleoside Analogs Uridine
6-Chloro-N1-(trimethylsilylethoxymethyl)pseudouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 3’-Azido-3’-deoxy-4-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154211

5'-O-DMTr-dU-methyl phosphonamidite		Phosphoramidites Uracil
5’-O-DMTr-dU-methyl phosphonamidite; 5’-O-DMTr-2’-deoxyuridine-3’-O-(P-methyl-N,N-diisopropylamino)phosphonamidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-158200

5-Aminoallyl-dUTP 5-Aminoallyl 2'-Deoxyuridine 5'-triphosphate		Nucleoside Analogs Nucleotide Analogs
5-Aminoallyl-dUTP (5-Aminoallyl 2'-deoxyuridine 5'-triphosphate) is a monomeric raw material that can be used for nucleic acid synthesis.

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