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recombinant-human-interferon-gamma

" in MedChemExpress (MCE) Product Catalog:

2040

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GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N7140
    Gamma-Linolenic acid
    5+ Cited Publications

    γ-Linolenic acid

    		 Endogenous Metabolite Apoptosis NF-κB ERK JNK Neurological Disease Inflammation/Immunology Cancer
    Gamma-linolenic acid (γ-Linolenic acid) is an orally active unsaturated fatty acid. Gamma-linolenic acid exerts anti-inflammatory effects by inhibiting the NF-κB pathway and the phosphorylation of ERK1/2 and JNK. At the same time, it exerts anticancer effects by inducing apoptosis (Apoptosis) in cancer cells. Additionally, Gamma-linolenic acid also has antioxidant and memory-improving effects. It holds promise for research in the fields of inflammation, neurology, and cancer diseases .
    Gamma-Linolenic acid
  • HY-N7148
    γ-Tocopherol
    1 Publications Verification

    D-γ-Tocopherol; (+)-γ-Tocopherol

    		 COX Endogenous Metabolite Inflammation/Immunology Cancer
    γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor. γ-Tocopherol is a naturally occurring form of Vitamin E in many plant seeds, such as corn oil and soybeans. γ-Tocopherol possesses antiinflammatory properties and anti-cancer activity .
    γ-Tocopherol
  • HY-N1957
    Gamma-Mangostin
    2 Publications Verification

    γ-Mangostin

    		 5-HT Receptor COX Transthyretin (TTR) Metabolic Disease Inflammation/Immunology Cancer
    Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3 H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
    Gamma-Mangostin
  • HY-112171
    γ-L-Glutamyl-L-alanine
    1 Publications Verification

    γ-Glu-Ala

    		 Endogenous Metabolite CaSR Others
    γ-L-Glutamyl-L-alanine (γ-Glu-Ala), composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function .
    γ-L-Glutamyl-L-alanine
  • HY-112103
    6-(γ,γ-Dimethylallylamino)purine

    N6-(2-lsopentenyl)adenine; Isopentenyladenine

    		 Others Others
    6-(γ,γ-Dimethylallylamino)purine is a plant growth substance.
    6-(γ,γ-Dimethylallylamino)purine
  • HY-W020183
    γ-Terpinene

    		Environmental Pollutants Fungal Bacterial Neurological Disease
    γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity. γ-Terpinene exhibits antimicrobial efficacy against various bacteria and fungi .
    γ-Terpinene
  • HY-P4717
    IFN-γ Antagonist 1

    		IFNAR Inflammation/Immunology
    IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) is an interferon-γ (IFN-γ) antagonist. IFN-γ Antagonist 1 inhibits IFN-γ-induced HLR/DR antigen expression in cells. IFN-γ Antagonist 1 can be used in researches of diseases with abnormal immune regulation .
    IFN-γ Antagonist 1
  • HY-131081
    γ-Amanitin

    		DNA/RNA Synthesis ADC Payload Cancer
    γ-Amanitin an ADC cytotoxin and isolated from the mushroom. γ-Amanitin inhibits RNA polymerase II and disrupts synthesis of mRNA. γ-Amanitin shows similar effects to α-Amanitin and β-Amanitin. γ-Amanitin competitively binds to monoclonal antibody (mAb), with an IC50 of 163.1 ng/mL. γ-Amanitin is toxic to a variety of cells .
    γ-Amanitin
  • HY-N13356
    L-gamma-Glutamyl-L-threonine

    gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr

    		 Bacterial Peptide-Drug Conjugates (PDCs) Drug Metabolite Infection Inflammation/Immunology
    L-gamma-Glutamyl-L-threonine (gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr) is a dipeptide obtained through the formal condensation of the L-glutamic acid side chain carboxyl group and the L-threonine amino group. L-gamma-Glutamyl-L-threonine is present in high concentrations in human urine and exhibits antibacterial activity against Gram-negative bacterial. L-gamma-Glutamyl-L-threonine is also a flavor compound. Gamma-Glutamylthreonine is a metabolite catalyzed by γ-glutamyl transpeptidase and is associated with immune regulation. Gamma-Glutamylthreonine can be used in research on inflammation and bacterial infections .
    L-gamma-Glutamyl-L-threonine
  • HY-W724905
    gamma-Glutamylisoleucine

    γ-Glu-Ile; H-γ-Glu-Ile-OH

    		 Amino Acid Derivatives Others
    gamma-Glutamylisoleucine (γ-Glu-Ile; H-γ-Glu-Ile-OH) is a dipeptide composed of γ-glutamic acid and isoleucine, and it is also a degradation product of macromolecular proteins after proteolysis .
    gamma-Glutamylisoleucine
  • HY-101399
    γ-Glu-Phe
    1 Publications Verification

    H-γ-Glu-Phe-OH; γ-Glutamylphenylalanine

    		 Endogenous Metabolite Others
    γ-Glu-Phe is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
    γ-Glu-Phe
  • HY-108694
    γ-Tocotrienol
    4 Publications Verification

    		 Endogenous Metabolite NF-κB Metabolic Disease Inflammation/Immunology
    γ-Tocotrienol is an active form of vitamin E. γ-tocotrienol reverses the multidrug resistance (MDR) of breast cancer cells through the signaling pathway of NF-κB and P-gp. γ-Tocotrienol is also a radioprotector agent, can mitigate bone marrow radiation damage during targeted radionuclide treatment .
    γ-Tocotrienol
  • HY-149449
    Poly-L-γ-glutamic acid sodium

    		Amino Acid Derivatives Cancer
    Poly-L-γ-glutamic acid sodium is a macromolecular polymer formed by the linkage of glutamic acid residues via peptide bonds between γ-amino and carboxyl groups. Poly-L-γ-glutamic acid sodium plays an important role as a carrier material in compound delivery systems. Poly-L-γ-glutamic acid sodium can deliver Paclitaxel (HY-B0015) to colon cancer cells, reduce cell viability and inhibit the growth of colon cancer spheroids. Poly-L-γ-glutamic acid sodium can be used as a carrier material and in studies related to colon cancer in mice .
    Poly-L-γ-glutamic acid sodium
  • HY-W015892
    γ-Hexalactone

    γ-Caprolactone

    		 Interleukin Related TNF Receptor Insecticide Infection
    γ-Hexalactone (γ-Caprolactone) is a gamma-lactone found in ripe fruits. γ-Hexalactone induces DNA damage in human lymphocytes and HepG2 cells, modulates cytokine secretion in human lymphocytes, and reduces recombinant PON1 activity. γ-Hexalactone serves as a dose-dependent oviposition inhibitor against Bactrocera oleae. γ-Hexalactone can be used for the research of Bactrocera oleae pest management .
    γ-Hexalactone
  • HY-N7105
    γ-Decalactone

    		Environmental Pollutants Others
    γ-Decalactone is a natural flavoring substance with the fruity aroma of juicy peaches. γ-Decalactone can be used as a food additive .
    γ-Decalactone
  • HY-P4376A
    Gamma-Glu-Abu TFA

    		CaSR Neurological Disease
    Gamma-Glu-Abu TFA is the TFA salt form of Gamma-Glu-Abu (HY-P4376). Gamma-Glu-Abu TFA is an agonist for calcium sensing receptor (CaSR), that activates the CaSR with an EC50 of 0.21 μM in HEK-293 cell .
    Gamma-Glu-Abu TFA
  • HY-N10477
    gamma-Glutamylarginine

    L-γ-Glutamyl-L-arginine; γ-Glu-Arg

    		 Amino Acid Derivatives Others
    gamma-Glutamylarginine (L-γ-Glutamyl-L-arginine), an γ-glutamic acid oligopeptide, can be isolated from Panax ginseng .
    gamma-Glutamylarginine
  • HY-12557
    γ-Glutamylvaline

    γ-Glu-Val

    		 Endogenous Metabolite CaSR Wnt TNF Receptor Interleukin Related PPAR β-catenin Inflammation/Immunology
    γ‑Glutamylvaline (γ-Glu-Val) is a calcium‑sensing receptor (CaSR) agonist. γ‑Glutamylvaline activates CaSR and facilitates its binding to β‑arrestin 2 to modulate inflammatory and metabolic homeostasis signaling. γ‑Glutamylvaline inhibits TNF‑α‑induced IL‑6/MCP‑1 and enhances adiponectin/PPARγ in adipocytes. γ‑Glutamylvaline upregulates Wnt5a, restores β‑catenin phosphorylation, and reduces serine‑phosphorylated IRS‑1 in adipocytes. γ-Glutamylvaline can be used for the research of low-grade chronic inflammation .
    γ-Glutamylvaline
  • HY-P4717A
    IFN-γ Antagonist 1 acetate

    		IFNAR Inflammation/Immunology
    IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate is an interferon-γ (IFN-γ) antagonist. IFN-γ Antagonist 1 acetate inhibits IFN-γ-induced HLR/DR antigen expression in cells. IFN-γ Antagonist 1 acetate can be used in researches of diseases with abnormal immune regulation .
    IFN-γ Antagonist 1 acetate
  • HY-100785
    gamma-DGG

    γDGG; γ-D-Glutamylglycine

    		 iGluR Neurological Disease
    gamma-DGG is a competitive AMPA receptor blocker.
    gamma-DGG
  • HY-P11200
    γ-Glu-Asn

    γ-Glutamylasparagine

    		 Calcium Channel Neurological Disease
    γ-Glu-Asn (γ-Glutamylasparagine) is a calcium sensing receptor (CaSR) agonist. γ-Glu-Asn is a dipeptide composed of glutamic acid and asparagine .
    γ-Glu-Asn
  • HY-P4632
    H-γ-Glu-Leu-OH
    1 Publications Verification

    γ-Glu-Leu

    		 Amino Acid Derivatives Others
    H-γ-Glu-Leu-OH (γ-Glu-Leu) is a dipeptide consisting of γ-glutamic acid and leucine, terminated by a hydroxyl group .
    H-γ-Glu-Leu-OH
  • HY-108396
    γ-Linolenic acid ethyl ester

    Ethyl γ-linolenate

    		 Leukotriene Receptor Inflammation/Immunology
    γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B4 receptor 4 (LTB4) antagonist .
    γ-Linolenic acid ethyl ester
  • HY-118090A
    D-γ-Glutamyl-D-glutamic acid

    D-γ-Glu-Glu; H-D-γ-Glu-Glu-OH

    		 Endogenous Metabolite Others
    D-γ-Glutamyl-D-glutamic acid is a poly(γ-glutamic acid) of clusters of D- and D-glutamic acid repeating units in a linear chain .
    D-γ-Glutamyl-D-glutamic acid
  • HY-P3280
    γ-Glu-Gly

    		Endogenous Metabolite Metabolic Disease
    γ-Glu-Gly, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids .
    γ-Glu-Gly
  • HY-P11201
    gamma-Glutamylaspartic acid

    γ-Glu-Asp

    		 Amino Acid Derivatives Others
    gamma-Glutamylaspartic acid (γ-Glu-Asp) is a γ-glutamyl dipeptide with kokumi activities .
    gamma-Glutamylaspartic acid
  • HY-N7148R
    γ-Tocopherol (Standard)

    D-γ-Tocopherol (Standard); (+)-γ-Tocopherol (Standard)

    		 Reference Standards COX Endogenous Metabolite Inflammation/Immunology Cancer
    γ-Tocopherol (Standard) is the analytical standard of γ-Tocopherol. This product is intended for research and analytical applications. γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor. γ-Tocopherol is a naturally occurring form of Vitamin E in many plant seeds, such as corn oil and soybeans. γ-Tocopherol possesses antiinflammatory properties and anti-cancer activity .
    γ-Tocopherol (Standard)
  • HY-138119
    γ-Glutamylserine

    γ-Glu-Ser

    		 Calcium Channel Neurological Disease Metabolic Disease
    γ-Glutamylserine (γ-Glu-Ser) is a calcium receptor activator. γ-Glutamylserine can be used for Parkinson's disease research, as well as diabetes or obesity study .
    γ-Glutamylserine
  • HY-113095
    γ-CEHC
    1 Publications Verification

    		 Drug Metabolite Endogenous Metabolite Others
    γ-CEHC is a γ-tocopherol (HY-N7148) metabolite. γ-CEHC is mainly excreted into the urine rather than into the bile. γ-CEHC is present in conjugated form in human urine, mainly as glucuronide .
    γ-CEHC
  • HY-N7148S1
    γ-Tocopherol-d4

    		Isotope-Labeled Compounds COX Inflammation/Immunology Cancer
    γ-Tocopherol-d4 is the deuterium labeled γ-Tocopherol. γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor. γ-Tocopherol is a naturally occurring form of Vitamin E in many plant seeds, such as corn oil and soybeans. γ-Tocopherol possesses antiinflammatory properties and anti-cancer activity .
    γ-Tocopherol-d4
  • HY-P1214
    γ1-MSH

    		Melanocortin Receptor Cardiovascular Disease
    γ1-MSH is a melanocortin MC3 receptor agonist, with a Ki of 34 nM for the rat MC3 receptor. γ1-MSH displays ~40-fold selectivity over MC4 (Ki=1318 nM) .
    γ1-MSH
  • HY-P11202
    gamma-Glutamylproline

    γ-Glu-Pro

    		 Amino Acid Derivatives Others
    gamma-Glutamylproline (γ-Glu-Pro) is a γ-glutamyl dipeptide with kokumi activities .
    gamma-Glutamylproline
  • HY-N7140R
    Gamma-Linolenic acid (Standard)
    5+ Cited Publications

    γ-Linolenic acid (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .
    Gamma-Linolenic acid (Standard)
  • HY-P11203
    γ-Glu-Lys

    L-γ-Glutamyl-L-lysine

    		 Amino Acid Derivatives Others
    γ-Glu-Lys (L-γ-Glutamyl-L-lysine) is a γ-glutamyl dipeptide .
    γ-Glu-Lys
  • HY-178335
    SGC-CK1γ-1

    		LDLR Wnt CMV Infection
    SGC-CK1γ-1 is a potent and selective probe for the CK1γ subfamily. SGC-CK1γ-1 can inhibit LRP6 phosphorylation levels. SGC-CK1γ-1 can selectively inhibit the CK1γ kinases in living cells and inhibit both WNT signaling and human cytomegalovirus (CMV) replication. SGC-CK1γ-1 can be used for the research of infection .
    SGC-CK1γ-1
  • HY-W275481
    γ-Dodecanolactone

    		Cytochrome P450 Others
    γ-Dodecanolactone is a γ-lactone compound. γ-Dodecanolactone exhibits inhibitory activity against CYP1A2 with an IC50 value of 58 µM and a pIC50 value of 4.24. γ-Dodecanolactone can be used in the research of diseases related to the CYP1A2 enzyme .
    γ-Dodecanolactone
  • HY-W017562
    γ-Octalactone

    		Environmental Pollutants Biochemical Assay Reagents Others
    γ-Octalactone is an aromatic lactone compound. γ-Octalactone has a strong fruity (similar to coconut) aroma and a sweet taste, and is commonly used in food, cosmetics and fragrances. γ-Octalactone is highly safe .
    γ-Octalactone
  • HY-128675
    γ-D-Glutamylaminomethylsulfonic acid

    γ-D-Glutamylaminomethylsulfonic acid

    		 Amino Acid Derivatives Others
    γ-D-Glutamylaminomethylsulfonic acid is a glutamic acid derivative .
    γ-D-Glutamylaminomethylsulfonic acid
  • HY-116015
    Dihomo-γ-Linolenic acid methyl ester

    		Endogenous Metabolite Inflammation/Immunology
    Dihomo-γ-Linolenic acid methyl ester is the methyl ester form of Dihomo-γ-Linolenic Acid (DGLA) (HY-A0143). Dihomo-γ-Linolenic acid is an n-6 polyunsaturated fatty acid that is metabolized mainly through the cyclooxygenase (COX) pathway to the anti-inflammatory eicosanoid prostaglandin (PG) E1. Dihomo-γ-Linolenic acid has anti-inflammatory and antiproliferation effects .
    Dihomo-γ-Linolenic acid methyl ester
  • HY-P4376
    Gamma-Glu-Abu

    		CaSR Neurological Disease
    Gamma-Glu-Abu is an agonist for calcium sensing receptor (CaSR), that activates the CaSR with an EC50 of 0.21 μM in HEK-293 cell .
    Gamma-Glu-Abu
  • HY-W587938
    γ-Eudesmol

    (+)-γ-Eudesmol

    		 Apoptosis Cancer
    γ-Eudesmol ((+)-γ-Eudesmol) is a mitochondrial-mediated apoptosis inducer. γ-Eudesmol binds mitochondrial membrane proteins, triggering depolarization of mitochondrial membrane potential and activating caspase cascades. γ-Eudesmol demonstrates cytotoxicity against multiple tumor cell lines (e.g., HepG2, B16-F10) with IC50 values ranging from 8.86-15.15 μg/mL. γ-Eudesmol is promising for research of cancers, such as hepatocellular carcinoma and melanoma .
    γ-Eudesmol
  • HY-114686
    (R)-γ-Valerolactone

    		Drug Metabolite Cardiovascular Disease
    (R)-γ-Valerolactone is a precursor of antihypertensive compounds. (R)-γ-Valerolactone can also be used in the research of biodegradable plastics and biofuels .
    (R)-γ-Valerolactone
  • HY-N7014
    Hydroxyl-​γ-​isosanshool

    		Others Neurological Disease
    Hydroxyl-γ-isosanshool is one of the major alkylamides in Z. bungeanum and Z. schinifolium oils. Hydroxyl-γ-isosanshoo induces a numbing sensation .
    Hydroxyl-​γ-​isosanshool
  • HY-108694R
    γ-Tocotrienol (Standard)

    		Reference Standards Endogenous Metabolite NF-κB Metabolic Disease Inflammation/Immunology
    γ-Tocotrienol (Standard) is the analytical standard of γ-Tocotrienol. This product is intended for research and analytical applications. γ-Tocotrienol is an active form of vitamin E. γ-tocotrienol reverses the multidrug resistance (MDR) of breast cancer cells through the signaling pathway of NF-κB and P-gp. γ-Tocotrienol is also a novel radioprotector agent, can mitigate bone marrow radiation damage during targeted radionuclide treatment .
    γ-Tocotrienol (Standard)
  • HY-P4633A
    D-γ-Glu-Tyr

    		Drug Isomer Dipeptidyl Peptidase Metabolic Disease
    D-γ-Glu-Tyr is a D-isomer of γ-Glu-Tyr (HY-P4633), the difference being the γ-Glu content.γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC50=6.77 mM), is a potentially functional component of the type 2 diabetes diet .
    D-γ-Glu-Tyr
  • HY-N1957R
    Gamma-Mangostin (Standard)

    γ-Mangostin (Standard)

    		 Reference Standards 5-HT Receptor COX Transthyretin (TTR) Metabolic Disease Inflammation/Immunology Cancer
    Gamma-Mangostin (Standard) is the analytical standard of Gamma-Mangostin. This product is intended for research and analytical applications. Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
    Gamma-Mangostin (Standard)
  • HY-115742
    (Rac)-γ-Tocopherol

    DMPBQ

    		 COX Cancer
    (Rac)-γ-Tocopherol (DMPBQ) is a Vitamin E isoform, which is converted by tocopherol cyclase to γ-Tcopherol .
    (Rac)-γ-Tocopherol
  • HY-177573
    Cholesteryl γ-aminobutyrate

    		GABA Receptor Neurological Disease
    Cholesteryl γ-aminobutyrate is a γ-aminobutyric acid (GABA)-mimetic prodrug. Cholesteryl γ-aminobutyrate inhibits the orthodromically-evoked discharge of pyramidal cells in the CA1 region of the hippocampus. Cholesteryl γ-aminobutyrate suppresses the open-field activity of mice and rats in a dose-dependent manner and inhibits Bicuculline (HY-N0219)-induced seizures in mice. Cholesteryl γ-aminobutyrate can be used for the study of CNS diseases related to impaired GABAergic neuronal function .
    Cholesteryl γ-aminobutyrate
  • HY-161016
    TNF/IFN-γ-IN-1

    		TNF Receptor IFNAR Neurological Disease
    TNF/IFN-γ-IN-1 (compound TGA) is a dual inhibitor of TNF and IFN-γ. TNF/IFN-γ-IN-1 can used in study Alzheimer’s disease .
    TNF/IFN-γ-IN-1
  • HY-W719989
    γ-Carotene

    		Drug Intermediate Metabolic Disease
    γ-Carotene is a carotenoid found in Hippophae rhamnoides L. and peach palm fruits. γ-Carotene exhibits no significant inhibitory activity against self-activated hepatic stellate cells in vitro. γ-Carotene can be converted into retinol (Vitamin A) (HY-B1342) and can be used for the research of vitamin A deficiency [2].
    γ-Carotene

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