CDK4 - cyclin dependent kinase 4 Gene

Also Known as CMM3; PSK-J3

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 1019

About CDK4

Cytogenetic location: 12q14.1 Genomic coordinates (GRCh38): 12:57,747,727-57,752,310 (from NCBI)

This gene has 15 transcripts (splice variants), 229 orthologues, 26 paralogues and is associated with 65 phenotypes. Ubiquitous expression in ovary (RPKM 36.9), endometrium (RPKM 35.9) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK Inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]

CDK4 Products (2)

mRNA	Protein	Name
NM_052984.1
NM_000075.4	NP_000066.1	cyclin-dependent kinase 4

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Verweise	Source
enables cyclin binding	IPI IPI: Inferred from physical interaction	19124461	GOA
enables cyclin-dependent protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	8114739	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	7568034	GOA

Biological Process GO Annotation	Evidence	Verweise	Source
involved in G1/S transition of mitotic cell cycle	IDA IDA: Inferred from direct assay	19237565	GOA
involved in G1/S transition of mitotic cell cycle	IMP IMP: Inferred from mutant phenotype	7603984	GOA
involved in positive regulation of G2/M transition of mitotic cell cycle	IDA IDA: Inferred from direct assay	19124461	GOA
involved in positive regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	7603984	GOA
involved in positive regulation of fibroblast proliferation	IMP IMP: Inferred from mutant phenotype	17420273	GOA
involved in protein phosphorylation	IDA IDA: Inferred from direct assay	8114739	GOA
involved in regulation of cell cycle	IDA IDA: Inferred from direct assay	19124461	GOA
involved in regulation of gene expression	IMP IMP: Inferred from mutant phenotype	17420273	GOA
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	18291362	GOA

Cellular Component GO Annotation	Evidence	Verweise	Source
located in chromatin	IDA IDA: Inferred from direct assay	18827403	GOA
part of cyclin D1-CDK4 complex	IPI IPI: Inferred from physical interaction	19237565	GOA
part of cyclin D2-CDK4 complex	IPI IPI: Inferred from physical interaction	11896535	GOA
part of cyclin D3-CDK4 complex	IPI IPI: Inferred from physical interaction	19237555	GOA
part of cyclin-dependent protein kinase holoenzyme complex	IDA IDA: Inferred from direct assay	17420273	GOA
located in cytosol	IDA IDA: Inferred from direct assay	18827403	GOA
located in nuclear membrane	IDA IDA: Inferred from direct assay	18827403	GOA
located in nucleolus	IDA IDA: Inferred from direct assay	18827403	GOA
located in nucleus	IDA IDA: Inferred from direct assay	16109376	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDK4 Protein Structure

Pkinase

0
100
200
303 a.a.

Protein Preferred Names	Protein Names
cyclin-dependent kinase 4	cell division protein kinase 4

CDK4 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Verweise
Intra	CDK4	P11802	CDC37	Homo sapiens	Q16543	Anti Tag CoIP	33961781
Intra	CDK4	P11802	CDC37	Homo sapiens	Q16543	Anti Tag CoIP	28514442
Intra	CDK4	P11802	CDC37	Homo sapiens	Q16543	Pull Down	32707033
Intra	CDK4	P11802	CDC37	Homo sapiens	Q16543	Anti Bait CoIP	17353931
Intra	CDK4	P11802	CDC37	Homo sapiens	Q16543	CoIP	9150368
Intra	CDK4	P11802	CDC37	Homo sapiens	Q16543	TAP	24981860
Intra	CDK4	P11802	APOBEC3B	Homo sapiens	Q9UH17	Anti Tag CoIP	31217276
Intra	CDK4	P11802	HSP90AB1	Homo sapiens	P08238	Pull Down	32707033
Intra	CDK4	P11802	HSP90AB1	Homo sapiens	P08238	TAP	23455922
Intra	CDK4	P11802	HSP90AB1	Homo sapiens	P08238	Anti Tag CoIP	33961781
Intra	CDK4	P11802	HSP90AB1	Homo sapiens	P08238	Anti Tag CoIP	28514442
Intra	CDK4	P11802	CCND1	Homo sapiens	P24385	Protein Kinase Assay	15681588
Intra	CDK4	P11802	CCND1	Homo sapiens	P24385	Protein Array	15232106
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	X-Ray Diffraction	19237555
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	Protein Array	15232106
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	Light Scattering	19237555
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	GMS	19237555
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	Anti Bait CoIP	14641107
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	Y2H	21988832
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	Validated Y2H	25910212
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	Anti Tag CoIP	26496610
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	Y2H Bait-Prey Pool	25910212
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	Y2H Array	25910212
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	Y2H	21516116
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	Y2H Array	25416956
Intra	CDK4	P11802	CCND3	Homo sapiens	P30281	SLC	25910212
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	TAP	24981860
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	Anti Tag CoIP	33961781
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	TAP	23602568
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	Anti Tag CoIP	26496610
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	TAP	23455922
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	Anti Bait CoIP	24855949
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	Anti Tag CoIP	28514442
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	Anti Bait CoIP	17909018
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	Pull Down	32707033
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	Anti Bait CoIP	17353931
Intra	CDK4	P11802	CDKN2A	Homo sapiens	P42771	Protein Array	15232106
Intra	CDK4	P11802	CDKN1A	Homo sapiens	P38936	Anti Tag CoIP	23543736
Intra	CDK4	P11802	CDKN1A	Homo sapiens	P38936	Anti Bait CoIP	9106657
Intra	CDK4	P11802	CDKN1A	Homo sapiens	P38936	Protein Kinase Assay	15681588
Intra	CDK4	P11802	CDKN1A	Homo sapiens	P38936	Anti Tag CoIP	28514442
Intra	CDK4	P11802	CDKN1A	Homo sapiens	P38936	Anti Bait CoIP	16962592
Intra	CDK4	P11802	OGDHL	Homo sapiens	Q9ULD0	Validated Y2H	32296183
Intra	CDK4	P11802	MYC	Homo sapiens	P01106	Y2H Array	21988832
Intra	CDK4	P11802	CDKN1C	Homo sapiens	P49918	Anti Bait CoIP	9106657
Intra	CDK4	P11802	CDKN1C	Homo sapiens	P49918	Anti Tag CoIP	33961781
Intra	CDK4	P11802	CDKN1B	Homo sapiens	P46527	Anti Bait CoIP	19470470
Intra	CDK4	P11802	CDKN1B	Homo sapiens	P46527	Anti Tag CoIP	23543736
Intra	CDK4	P11802	CDKN1B	Homo sapiens	P46527	PLA	25241761
Intra	CDK4	P11802	CDKN1B	Homo sapiens	P46527	TAP	23602568
Intra	CDK4	P11802	CDKN1B	Homo sapiens	P46527	Anti Tag CoIP	28514442
Intra	CDK4	P11802	CDKN1B	Homo sapiens	P46527	Anti Tag CoIP	33961781
Intra	CDK4	P11802	CDKN1B	Homo sapiens	P46527	Pull Down	32707033
Intra	CDK4	P11802	ZNF655	Homo sapiens	Q8N720	Validated Y2H	32296183
Intra	CDK4	P11802	ZNF655	Homo sapiens	Q8N720	Y2H Array	32296183
Intra	CDK4	P11802	ZNF655	Homo sapiens	Q8N720	Y2H Prey Pooling	32296183
Intra	CDK4	P11802	ZNF655	Homo sapiens	Q8N720	CoIP	15558030
Intra	CDK4	P11802	INCA1	Homo sapiens	Q0VD86	Y2H Prey Pooling	32296183
Intra	CDK4	P11802	INCA1	Homo sapiens	Q0VD86	Validated Y2H	32296183
Intra	CDK4	P11802	INCA1	Homo sapiens	Q0VD86	Y2H Array	32296183
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Y2H Pooling	16189514
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Y2H Pooling	19447967
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	SLC	25910212
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	TAP	23455922
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Validated Y2H	25910212
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Validated Y2H	32296183
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Y2H Array	25910212
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Anti Tag CoIP	26496610
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Anti Tag CoIP	33961781
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Y2H Bait-Prey Pool	25910212
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Y2H Pooling	16169070
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Anti Tag CoIP	28514442
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Pull Down	32707033
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	TAP	24981860
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	Anti Tag CoIP	23602568
Intra	CDK4	P11802	CDKN2B	Homo sapiens	P42772	TAP	23602568
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Validated Y2H	25416956
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	TAP	23455922
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Validated Y2H	32296183
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Y2H Array	25416956
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Anti Tag CoIP	35271311
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Anti Tag CoIP	25416956
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Y2H Prey Pooling	25416956
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Validated Y2H	27107012
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Y2H Array	21988832
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	TAP	24981860
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Validated Y2H	25910212
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	TAP	23602568
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Y2H Array	31515488
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Y2H Bait-Prey Pool	25910212
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	SLC	25910212
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Pull Down	32707033
Intra	CDK4	P11802	CDKN2C	Homo sapiens	P42773	Y2H Array	25910212
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	SLC	27107012
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Y2H Bait-Prey Pool	25910212
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	BFG-2H	27107012
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Y2H Array	25910212
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	TAP	23602568
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Y2H	27107012
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Anti Tag CoIP	28514442
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Validated Y2H	32296183
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Y2H Array	25416956
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Y2H Array	32296183
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Pull Down	32707033
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Validated Y2H	27107012
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Y2H Prey Pooling	32296183
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	TAP	24981860
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Validated Y2H	25910212
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Y2H Array	31515488
Intra	CDK4	P11802	CDKN2D	Homo sapiens	P55273	Y2H Pooling	16189514
Intra	CDK4	P11802	HOOK1	Homo sapiens	Q9UJC3	Y2H Array	25416956
Intra	CDK4	P11802	HOOK1	Homo sapiens	Q9UJC3	Validated Y2H	25910212
Intra	CDK4	P11802	HOOK1	Homo sapiens	Q9UJC3	Y2H Bait-Prey Pool	25910212
Intra	CDK4	P11802	HOOK1	Homo sapiens	Q9UJC3	Y2H Array	32296183
Intra	CDK4	P11802	HOOK1	Homo sapiens	Q9UJC3	SLC	25910212
Intra	CDK4	P11802	HOOK1	Homo sapiens	Q9UJC3	Validated Y2H	32296183
Intra	CDK4	P11802	HOOK1	Homo sapiens	Q9UJC3	Y2H Prey Pooling	25416956
Intra	CDK4	P11802	HOOK1	Homo sapiens	Q9UJC3	Y2H Array	25910212
Intra	CDK4	P11802	HOOK1	Homo sapiens	Q9UJC3	Y2H Prey Pooling	32296183
Intra	CDK4	P11802	IKZF3	Homo sapiens	Q9UKT9	Y2H Prey Pooling	32296183
Intra	CDK4	P11802	IKZF3	Homo sapiens	Q9UKT9	Y2H Array	32296183
Intra	CDK4	P11802	IKZF3	Homo sapiens	Q9UKT9	Validated Y2H	32296183
Intra	CDK4	P11802	CCND2	Homo sapiens	P30279	Validated Y2H	25910212
Intra	CDK4	P11802	CCND2	Homo sapiens	P30279	Validated Y2H	27107012
Intra	CDK4	P11802	CCND2	Homo sapiens	P30279	Y2H Array	25910212
Intra	CDK4	P11802	CCND2	Homo sapiens	P30279	Y2H Prey Pooling	32296183
Intra	CDK4	P11802	CCND2	Homo sapiens	P30279	SLC	25910212
Intra	CDK4	P11802	CCND2	Homo sapiens	P30279	Validated Y2H	32296183
Intra	CDK4	P11802	CCND2	Homo sapiens	P30279	Y2H Bait-Prey Pool	25910212
Intra	CDK4	P11802	CCND2	Homo sapiens	P30279	BFG-2H	27107012
Intra	CDK4	P11802	CCND2	Homo sapiens	P30279	Y2H Array	32296183
Intra	CDK4	P11802	CCND2	Homo sapiens	P30279	Anti Bait CoIP	11896535
Intra	CDK4	P11802	RBL2	Homo sapiens	Q08999	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

CDK4 Antibodies

Art. -Nr.	Produktname	Anwendung	Reactivity
HY-P80077	Cdk4 Antibody (YA513)	WB, ICC/IF, IHC-P, IP	Human, Mouse
HY-P84066	CDK4 Antibody (YA3763)	IHC-P, ICC/IF, FC, ELISA	Human
HY-P84066A	CDK4 Antibody (YA3763)(PBS only)	IHC-P, ICC/IF, FC, ELISA	Human
HY-P84067	CDK4 Antibody (YA3764)	WB, IHC-P, FC, ELISA	Human, Mouse, Monkey
HY-P84067A	CDK4 Antibody (YA3764)(PBS only)	WB, IHC-P, FC, ELISA	Human, Mouse, Monkey
HY-P85531	CDK4 Antibody (YA5223)	WB	Human, Mouse, Rat
HY-P86471	CDK4 Antibody (YA6163)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Familial Retinoblastoma	Hereditary Retinoblastoma Retinoblastoma
Skin Carcinoma	Skin Cancer Carcinoma Of Skin Ca - Skin Cancer Cancer Of Skin Malignant Neoplasm Of Skin Melanoma And Non-Melanoma Skin Cancer Skin Cancers Cancer, Skin
Mediastinum Liposarcoma	Liposarcoma Of Mediastinum
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Diffuse Large B-Cell Lymphoma	Dlbcl Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Large B-Cell Diffuse Lymphoma Lymphoma, Large B-Cell, Diffuse Dlbcl - [Diffuse Large B-Cell Lymphoma] Diffuse Large Beta Cell Lymphoma
Squamous Cell Carcinoma, Head And Neck	Squamous Cell Carcinoma Of The Head And Neck HNSCC Head And Neck Squamous Cell Carcinoma Head And Neck Cancer Squamous Cell Carcinoma Of Lip Squamous Cell Carcinoma, Head And Neck, Somatic Carcinoma Of The Head And Neck Squamous Cell Carcinomas Of Head And Neck Scchn Squamous Cell Carcinoma Of The Hypopharynx Squamous Cell Carcinoma Of The Oropharynx Squamous Cell Carcinoma Of Salivary Glands Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses Squamous Cell Carcinoma Of The Oral Cavity Squamous Cell Carcinoma Of The Lip Carcinoma, Squamous Cell Of Head And Neck Lip Squamous Cell Carcinoma Cancer, Head/Neck Carcinoma, Squamous Cell, Head And Neck Salivary Gland Squamous Cell Carcinoma Cancer Of Head And Neck Squamous Cell Carcinoma Of Oropharynx Nos
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Pleomorphic Liposarcoma	Pls Liposarcoma Pleomorphic Liposarcoma, Pleomorphic
Liposarcoma	Lipomatous Cancer
Peripheral Osteosarcoma	Surface Osteosarcoma Bone Surface Osteosarcoma
Extraosseous Osteosarcoma	Extraskeletal Osteosarcoma Extraskeletal Osteogenic Sarcoma
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Leukemia, Acute Lymphoblastic	Acute Lymphoblastic Leukemia ALL Acute Lymphocytic Leukemia Leukemia, Acute Lymphocytic, Susceptibility To, 1 Acute Lymphoblastic Leukaemia Precursor Lymphoblastic Lymphoma/Leukemia Precursor Lymphoid Neoplasm Leukemia, Acute Lymphoblastic, Susceptibility To B-Cell Acute Lymphoblastic Leukemia Leukemia, Acute Lymphocytic 1 Acute Lymphocytic Leukaemia Acute Lymphoblastic Leukemia/Lymphoma All1 Childhood Acute Lymphoblastic Leukemia Leukemia Acute Lymphoblastic 1 Leukemia Acute Lymphoblastic B-Hyperdiploid Leukemia Acute Lymphocytic Leukemia Acute Lymphocytic 1 Leukemia B-Cell Acute Lymphoblastic Leukemia T-Cell Acute Lymphoblastic Leukemia, Acute Lymphoblastic, 3 ALL3 Lymphoblastic Leukemia Acute Leukemia, Acute, Lymphoblastic Precursor Cell Lymphoblastic Leukemia Lymphoma Leukemia, Lymphocytic, Acute, L1 Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Melanoma, Cutaneous Malignant 3	Melanoma, Cutaneous Malignant, Susceptibility To, 3 CMM3 Melanoma, Cutaneous Malignant, 3 Cutaneous Malignant Melanoma 3 Melanoma, Cutaneous, Malignant, Susceptibility To, Type 3
Squamous Cell Carcinoma	Epidermoid Carcinoma Squamous Cell Cancer Carcinoma, Squamous Cell Malignant Squamous Cell Tumor Squamous Carcinoma Squamous Cell Epithelioma Squamous Cell Skin Cancer Carcinoma Squamous Cell Neoplasms, Squamous Cell Squamous Cell Carcinoma - Category Malignant Squamous Cell Neoplasm Squamous Cell Carcinoma Of Skin
Nasopharyngeal Carcinoma	Malignant Neoplasm Of Nasopharynx Npc Nasopharyngeal Cancer Nasopharyngeal Carcinoma 1 Nasopharynx Carcinoma Nasopharyngeal Neoplasms Npca Carcinoma Of Nasopharynx Malignant Nasopharyngeal Tumor Nasopharynx Cancer Squamous Cell Carcinoma Of The Nasopharynx Nasopharyngeal Neoplasm Cancer Of Nasopharynx
Plasma Cell Leukemia	Plasma Cell Leukaemia Leukemia, Plasma Cell Plasmacytic Leukaemia Plasmacytic Leukemia Pcl Plasma Cell Leukaemia, Nos Leukemic Plasma Cell Plasma Cell Leukaemia Without Mention Of Remission
Anaplastic Astrocytoma	Grade Iii Astrocytoma Grade Iii Astrocytic Tumor Astrocytoma, Anaplastic
Lung Cancer Susceptibility 3	Lung Adenocarcinoma Adenocarcinoma Of Lung LNCR3 Adenocarcinoma Of Lung, Susceptibility To Bronchogenic Lung Adenocarcinoma Nonsmall Cell Adenocarcinoma Adenocarcinoma Lung Lung Adenocarcinomas Non-Small Cell Adenocarcinoma
B-Cell Lymphoma	Lymphoma, B-Cell B-Cell Lymphomas B-Cell Lymphocytic Neoplasm Lymphoma B-Cell B-Cell Lymphoma Nos
Pleomorphic Lipoma	Lipoma Lipoma Pleomorphic Lipomatosis, Multiple
Skin Melanoma	Cutaneous Melanoma Malignant Ear Melanoma Malignant Lip Melanoma Malignant Lower Limb Melanoma Malignant Melanoma Of Ear And/Or External Auricular Canal Malignant Melanoma Of Skin Of Lower Limb Malignant Melanoma Of Skin Of Trunk Except Scrotum Malignant Melanoma Of Skin Of Upper Limb Malignant Neck Melanoma Malignant Scalp Melanoma Malignant Trunk Melanoma Malignant Upper Limb Melanoma Melanoma, Cutaneous Malignant Melanoma Malignant Melanoma Of Skin Melanoma Nos Malignant Mole, Meaning Melanoma Of Unspecified Site Melanoma Of Unspecified Site Cutaneous Malignant Melanoma Mm - [Malignant Melanoma]
Chondrosarcoma	Cartilaginous Cancer Chondrosarcoma Of Bone Primary Chondrosarcoma Of The Bone CHDSA
Pancreas Sarcoma	Sarcoma Of Pancreas
Mesothelioma, Malignant	Malignant Mesothelioma Pleural Mesothelioma MESOM Mesothelioma, Somatic Advanced Malignant Mesothelioma Asbestos-Related Malignant Mesothelioma Diffuse Malignant Mesothelioma Malignant Tumor Of Mesothelium Malignant Mesothelioma, Susceptibility To Mesothelioma Diffuse Malignant Mesothelioma Malignant Pleural Mesothelioma
Dedifferentiated Liposarcoma	Ddls Liposarcoma Dedifferentiated Liposarcoma, Dedifferentiated
Retinal Cancer	Malignant Neoplasm Of Retina Retinal Neoplasms Malignant Retinal Neoplasm Malignant Tumor Of Retina Neoplasm Of Retina Retinal Tumor Retinal Neoplasm Cancer Of The Retina Malignant Retinal Tumour Malignant Tumour Of Retina Primary Malignant Neoplasm Of Retina
Sarcoma	Connective And Soft Tissue Neoplasm Tumor Of Soft Tissue And Skeleton Sarcomas Sarcoma - Category
Lipoma Of Spermatic Cord	Spermatic Cord Lipoma
Conventional Osteosarcoma	Intracortical Osteosarcoma Conventional Central Osteosarcoma Intracortical Osteogenic Sarcoma Medullary Osteosarcoma
Oligodendroglioma	Oligodendroglial Neoplasm Oligodendroglial Tumor Oligodendroglial Tumors Well Differentiated Oligodendroglioma
Li-Fraumeni Syndrome	Sarcoma Family Syndrome Of Li And Fraumeni Sbla Syndrome LFS Li-Fraumeni Familiar Cancer Susceptibility Syndrome Sarcoma, Breast, Leukaemia And Adrenal Gland Syndrome Lfs1 Li Fraumeni Syndrome Sarcoma, Breast, Leukemia, And Adrenal Gland Syndrome Lfl Sbla Syndrome Li-Fraumeni-Like Syndrome Li-Fraumeni Syndrome 1
Lymphoma	Lymphoid Cancer Lymphomas Lymphoid Cancers Lymphoid Neoplasm Lymphoma Nos Nhl - [Non-Hodgkin Lymphoma] Non-Hodgkin Lymphoma Non-Hodgkin Lymphoma, Nos Non-Hodgkin Malignant Lymphoma Nos
Acral Lentiginous Melanoma	Acral Lentiginous Melanoma, Malignant Malignant Acral Lentiginous Melanoma Alm Acral Lentiginous Malignant Melanoma Of Skin Palmar/Plantar Melanoma Subungual Melanoma Acral Lentiginous Malignant Melanoma
Myxofibrosarcoma	Fibromyxosarcoma Fibromyxoid Sarcoma Myxoid Malignant Fibrous Histiocytoma Dermatofibrosarcoma Protuberans, Myxoid
Leiomyosarcoma	Leiomyosarcomas
Sensory System Disease
Lipoma Of Colon	Colonic Lipoma Colon Lipoma
Ischemic Fasciitis	Atypical Decubital Fibroplasia
Ocular Cancer	Eye Carcinoma Eye Neoplasm Eye Cancer Eye Neoplasms Malignant Eye Neoplasm Neoplasm Of Eye Neoplasm Of Eye Proper Ocular Tumor Carcinoma Of Eye Ocular Carcinoma Malignant Tumor Of Eye
Mucosal Melanoma
External Ear Squamous Cell Carcinoma	Epidermoid Carcinoma Of The External Ear Squamous Cell Carcinoma Of External Ear
Myeloma, Multiple	Multiple Myeloma Kahler Disease Myelomatosis Plasma Cell Myeloma Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler'S Disease Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Estrogen-Receptor Positive Breast Cancer
Spindle Cell Lipoma
Retinoblastoma	RB Trilateral Retinoblastoma RB1 Retinoblastoma, Trilateral Neuroblastoma Of Retina Rb - Retinoblastoma Eye Cancer, Retinoblastoma Retinal Cancer Retinal Tumor Glioma, Retinal Non-Hereditary Retinoblastoma Childhood Cancer Retinoblastoma Malignant Neoplasm Of Retina Retinal Neoplasms
Muscle Cancer	Myosarcoma Malignant Neoplasm Of Muscle Malignant Tumor Of Muscle Malignant Tumor Of The Muscle Muscle Neoplasms Myomatous Neoplasm
Inherited Cancer-Predisposing Syndrome	Hereditary Cancer-Predisposing Syndrome
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Well-Differentiated Liposarcoma	Atypical Lipomatous Tumor Atypical Lipoma Alt Wdls Liposarcoma, Well Differentiated Pleomorphic Lipoma
Malignant Inflammatory Fibrous Histiocytoma	Inflammatory Mfh Xanthosarcoma
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Gastrointestinal Stromal Tumor	GIST Gastrointestinal Stromal Tumors Gastrointestinal Stromal Sarcoma Gastrointestinal Stromal Tumor, Familial Gant Gastrointestinal Stromal Tumour Stromal Tumor Of Gastrointestinal Tract Stromal Tumour Of Gastrointestinal Tract Gastrointestinal Stromal Neoplasm Paraganglioma And Gastric Stromal Sarcoma Plexosarcoma
Anaplastic Oligodendroglioma
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Bone Osteosarcoma	Osteosarcoma Of Bone Primary Osteosarcoma Of Bone
Hereditary Breast Ovarian Cancer Syndrome	Hereditary Breast And Ovarian Cancer Syndrome Brca1- And Brca2-Associated Hereditary Breast And Ovarian Cancer Breast And/Or Ovarian Cancer Breast And Ovarian Cancer Syndrome Hboc Syndrome Hereditary Breast And Ovarian Cancer Brca1- Brca2-Associated Hboc
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1
Melanoma, Uveal	Uveal Melanoma Choroidal Melanoma Melanoma Of Uvea Iris Melanoma Malignant Melanoma Of Choroid Malignant Melanoma Of Iris
High Grade Glioma	Malignant Glioma Glial Cell Tumor Glioma, Malignant Malignant Neuroglial Tumor Neuroglial Tumor Glioma Malignant Gliomas
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Adult Liposarcoma
Infiltrating Lipoma	Intramuscular Lipoma
Burkitt Lymphoma	Burkitt'S Lymphoma BL Burkitt Lymphoma, Somatic Burkitt Lymphoma/Leukaemia Burkitt'S Tumor Burkitt'S Tumor Or Lymphoma Malignant Lymphoma, Burkitt'S Type Small Non-Cleaved Cell Lymphoma, Burkitt'S Type Small Non-Cleaved Cell Lymphoma Burkitt Tumor Burkitts Lymphoma Lymphoma, Small Noncleaved-Cell Burkitt Tumour Diffuse Small Noncleaved Malignant Burkitt Lymphoma Malignant Burkitt Lymphoma “Burkitt-Like” Lymphoma Undifferentiated Burkitt Lymphoma Small Noncleaved Cell Burkitt Lymphoma
Retinal Disease	Retinal Diseases Retinal Disorder Retinal Disorders
Large Intestine Lipoma	Lipoma Of Large Intestine Colorectal Lipoma
Adenocarcinoma	Adenocarcinomas Adenoacanthoma Of Unspecified Site Adenocarcinoid Of Unspecified Site Adenocarcinoid Tumour Of Unspecified Site Adenocarcinoma And Carcinoid Combined Of Unspecified Site Adenocarcinoma Nos
Cellular Myxoid Liposarcoma	Round Cell Liposarcoma
Melanoma	Malignant Melanoma Cutaneous Melanoma Naevocarcinoma Malignant Melanomas
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Heart Sarcoma	Cardiac Sarcoma Sarcoma Of Heart
Infiltrating Angiolipoma	Angiolipoma, Infiltrating
Neuroblastoma	Nb Neuroblastoma, Susceptibility To Neuroblastomas Central Neuroblastoma
Osteogenic Sarcoma	Osteosarcoma OSRC Osteosarcoma, Somatic Neoplasms, Bone Tissue Bone Tissue Neoplasm Osteoid Sarcoma Skeletal Sarcoma Osteosarcoma Of Bone Bone Sarcoma
Pilocytic Astrocytoma	Juvenile Pilocytic Astrocytoma Grade I Astrocytic Tumor Piloid Astrocytoma
Melanoma In Congenital Melanocytic Nevus	Malignant Melanoma In Congenital Melanocytic Nevus Melanocytic Nevi Nevi Melanocytic
Medulloblastoma	MDB Cpnet Localized Primitive Neuroectodermal Tumor Classic Medulloblastoma Desmoplastic/Nodular Medulloblastoma Medulloblastoma With Extensive Nodularity Desmoplastic Medulloblastoma Medulloblastoma, Somatic Medulloblastoma, Desmoplastic Brain Medulloblastoma Cns Pnet Infratentorial Primitive Neuroectodermal Tumor Mben Medulloblastoma Desmoplastic Neuroectodermal Tumors, Primitive Medulloblastomas Medulloblastoma, With Extensive Nodularity Medulloblastoma Of Unspecified Site Medullomyoblastoma Of Unspecified Site
Childhood Liposarcoma	Pediatric Liposarcoma
Chest Wall Lipoma	Lipoma Of The Chest Wall Lipoma Of Chest Wall
Bone Sarcoma
Pancreatic Adenocarcinoma	Adenocarcinoma Of Pancreas Adenocarcinoma Of The Pancreas Pancreas Adenocarcinoma Malignant Exocrine Neoplasm Primary Pancreatic Adenocarcinoma Adenocarcinoma Of Islet Cell Of Pancreas Islet Cell Adenocarcinoma Of Unspecified Site Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site
Skeletal Muscle Cancer	Malignant Tumor Of Skeletal Muscle Skeletal Muscle Neoplasm
Myositis Ossificans	Myisitis Ossificans Ossification - Muscle
Large Cell Carcinoma	Carcinoma, Large Cell Carcinoma Large Cell
External Ear Carcinoma	Carcinoma Of External Ear Carcinoma Of The External Ear
Clivus Chondroid Chordoma	Chondroid Chordoma Of The Clivus
Retroperitoneal Sarcoma
Brain Cancer	Malignant Neoplasm Of Brain Adult Brain Tumor Brain Neoplasms Brain Neoplasm Neoplasm Of Brain Primary Malignant Neoplasm Of Brain Brain Tumors Adult Malignant Brain Neoplasm Brain Neoplasm, Adult Bt - Brain Tumour Malignant Brain Tumour Malignant Primary Brain Neoplasm Malignant Primary Brain Tumor Malignant Tumor Of Adult Brain Malignant Tumor Of Brain Primary Brain Neoplasm Primary Brain Tumor Tumor Of The Brain Brain Tumor, Adult Brain Tumor Primary Malignant Primary Brain Tumors Primary Brain Tumors Cancer, Brain Brain Tumor, Primary
Parosteal Osteosarcoma	Juxtacortical Osteosarcoma Parosteal Osteogenic Sarcoma Osteosarcoma, Juxtacortical
Inflammatory Liposarcoma
Female Breast Cancer	Female Breast Carcinoma Carcinoma Of Female Breast Mammary Carcinoma Of Female Breast Malignant Neoplasm Of Female Breast
Embryonal Rhabdomyosarcoma	Rhabdomyosarcoma, Embryonal Rhabdomyosarcoma Embryonal Botryoid Rhabdomyosarcoma Erms Spindle Cell Rhabdomyosarcomas
Bladder Cancer	Urinary Bladder Cancer Bladder Carcinoma Urinary Bladder Carcinoma Bladder Neoplasm Bladder Tumor Cancer, Bladder Malignant Neoplasm Of Urinary Bladder Carcinoma Of Bladder Bladder Cancer, Somatic Tumor Of The Bladder Carcinoma Of Urinary Bladder Bladder Carcinoma Urinary Cancer Of The Urinary Bladder Cancer, Urinary Bladder Malignant Bladder Neoplasm Malignant Bladder Tumor Neoplasm Of The Bladder Neoplasm Of The Urinary Bladder Tumor Of The Urinary Bladder Urinary Bladder Neoplasm BLC Urothelial Carcinoma Of The Bladder Bladder Tumors Urinary Bladder Neoplasms Bladder Cancer Nos Vesical Cancer Nos Malignant Neoplasm Of Bladder, Part Unspecified Malignant Tumour Of Urinary Bladder Primary Malignant Neoplasm Of Bladder
Myxoid Liposarcoma	Myxoid/Round Cell Liposarcoma Liposarcoma, Myxoid Mrcls Myxoliposarcoma MXLIPO Liposarcoma Myxoid Liposarcoma
Tumor Predisposition Syndrome	TPDS Tumor Predisposition
Malignant Peripheral Nerve Sheath Tumor	Mpnst Malignant Neurilemmoma Neurofibrosarcoma Malignant Neurofibroma Malignant Schwannoma Neurogenic Sarcoma Malignant Neoplasm Of The Peripheral Nerve Sheath Schwannoma, Malignant Malignant Peripheral Nerve Sheath Tumors
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Cancer Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Pancreatic Cancer	Pancreatic Carcinoma Familial Pancreatic Carcinoma Pancreatic Neoplasm Carcinoma Of Pancreas Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Cancer Of The Pancreas Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Melanoma, Cutaneous Malignant 1	Familial Melanoma Melanoma, Cutaneous Malignant, Susceptibility To, 1 CMM1 Melanoma, Cutaneous Malignant Cmm Melanoma, Malignant Familial Atypical Mole-Malignant Melanoma Syndrome Fammm Melanoma, Familial Mlm Dysplastic Nevus Syndrome, Hereditary Dns B-K Mole Syndrome Melanoma, Cutaneous Malignant, 1 Malignant Melanoma, Cutaneous Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1 Dysplastic Nevus Syndrome Cutaneous Melanoma Familial Atypical Mole Melanoma Syndrome Hereditary Melanoma
Gastric Liposarcoma	Liposarcoma Of The Stomach
Nodular Malignant Melanoma	Nodular Melanoma
Esophagus Squamous Cell Carcinoma	Esophageal Squamous Cell Carcinoma Oesophagus Squamous Cell Carcinoma Scc Of Esophagus Scc Of Oesophagus Squamous Cell Carcinoma Of The Esophagus Escc Esophageal Epidermoid Carcinoma Squamous Cell Esophageal Cancer Squamous Cell Carcinoma Of Esophagus
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Protection Against Lung Cancer, Susceptibility To Adenocarcinoma Of Lung, Somatic Nonsmall Cell Lung Cancer Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Paratesticular Lipoma
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Leukemia, Myeloid, Acute Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Lipomatosis, Multiple	Lipoma Familial Multiple Lipomatosis Lipomatosis, Familial Multiple Benign Lipomatous Tumor Lipomatous Neoplasm Multiple Lipomatosis Fml Lipo Benign Tumor Of Adipose Tissue Lipomatous Tumor Tumor Of Adipose Tissue Neoplasms, Adipose Tissue Lipomas
Breast Adenocarcinoma	Mammary Adenocarcinoma Adenocarcinoma Of Breast
Spindle Cell Liposarcoma
Mixed Liposarcoma	Mixed-Type Liposarcoma Myxoid/Round Cell Liposarcoma
Kidney Liposarcoma	Liposarcoma Of Kidney
Mantle Cell Lymphoma	Lymphoma, Mantle Cell Lcm Mcl Mantle Zone Lymphoma Lymphoma Mantle-Cell Lymphoma, Mantle-Cell Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse Malignant Lymphoma - Lymphocytic, Intermediate Differentiation Diffuse Small Cleaved-Cell Lymphoma Diffuse Small Cleaved Cell Malignant Lymphoma Small Cleaved Cell Non-Hodgkin Lymphoma Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma Malignant Lymphomatous Polyposis Malignant Small Cell, Noncleaved, Diffuse Lymphoma Malignant Undifferentiated Cell, Non-Burkitt Lymphoma Cleaved Cell Lymphoma Small Cell Mantle Cell Lymphoma Small Cleaved Cell Malignant Lymphoma
Gliosarcoma	Glioblastoma With Sarcomatous Component Sarcomatous Glioblastoma
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Connective Tissue Benign Neoplasm	Soft Tissue Neoplasms Mesenchymal Tissue Neoplasm Neoplasm Of Soft Tissue Neoplasm Of Soft Tissues Soft Tissue Benign Neoplasm Tumor Of The Soft Tissue Soft Tissue Neoplasm
Glioblastoma	Glioblastoma Multiforme Gbm Adult Glioblastoma Multiforme Grade Iv Adult Astrocytic Tumor Primary Glioblastoma Multiforme Spongioblastoma Multiforme Adult Glioblastoma Primary Glioblastoma
Rhabdomyosarcoma 2	Alveolar Rhabdomyosarcoma Rhabdomyosarcoma, Alveolar Rhabdomyosarcoma Alveolar RMS2 Rmsa Rhabdomyosarcoma 2, Alveolar Alveolar Childhood Rhabdomyosarcoma Arms Rhabdomyosarcoma, Type 2
Rhabdomyosarcoma
Plasma Cell Neoplasm	Plasma Cell Dyscrasia Paraproteinemias Plasma Cell Tumour Plasmacytic Tumor Multiple Myeloma Plasmacytoma Plasma Cell Tumours Plasma Cells Dyscrasia
Lynch Syndrome	Hereditary Nonpolyposis Colon Cancer Hereditary Nonpolyposis Colorectal Cancer Hereditary Nonpolyposis Colorectal Carcinoma Hereditary Nonpolyposis Colorectal Neoplasms Familial Nonpolyposis Colon Cancer Hnpcc Coca 1 Hereditary Defective Mismatch Repair Syndrome Hereditary Non-Polyposis Colon Cancer Hereditary Non-Polyposis Colon Cancer Syndrome Hereditary Non-Polyposis Colorectal Cancer Hereditary Non-Polyposis Colorectal Cancer Syndrome Hereditary Nonpolyposis Colon Cancer Syndrome Hereditary Nonpolyposis Colorectal Cancer Syndrome Hereditary Nonpolyposis Colorectal Neoplasm Hnpcc - Hereditary Nonpolyposis Colon Cancer Cancer Family Syndrome Familial Nonpolyposis Colorectal Cancer Colon Cancer, Familial Nonpolyposis Colorectal Neoplasms, Hereditary Nonpolyposis Cancer, Colorectal, Nonpolyposis, Hereditary Colorectal Cancer, Hereditary Nonpolyposis, Type 1
Hereditary Melanoma	Familial Cutaneous Melanoma Familial Melanoma Hereditary Cutaneous Melanoma Hereditary Cutaneous Melanoma
Malignant Fibrous Histiocytoma	Undifferentiated Pleomorphic Sarcoma Ups Fibroxanthosarcoma Mfh Malignant Fibrohistiocytic Tumors Histiocytoma, Malignant Fibrous Histiocytoma, Fibrous, Malignant

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (14)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-50767	Palbociclib	Inhibitor	99.94%	Unkown
HY-16297A	Abemaciclib	Inhibitor	99.97%	Yes
HY-15777	Ribociclib	Inhibitor	99.94%	Unkown
HY-50767C	Palbociclib hydrochloride	Inhibitor	99.96%	Unkown
HY-50767A	Palbociclib monohydrochloride	Inhibitor	99.98%	Unkown
HY-16297	Abemaciclib methanesulfonate	Inhibitor	99.95%	Yes
HY-A0065	Palbociclib isethionate	Inhibitor	99.98%	Unkown
HY-15777B	Ribociclib succinate	Inhibitor	99.93%	Unkown
HY-15777A	Ribociclib hydrochloride	Inhibitor	99.95%	Unkown
HY-114338	Dalpiciclib	Inhibitor	99.70%	Unkown
HY-101467A	Trilaciclib hydrochloride	Inhibitor	99.69%	Unkown
HY-15777C	Ribociclib succinate hydrate	Inhibitor	99.94%	Unkown
HY-50767D	Palbociclib orotate	Inhibitor	/	Unkown
HY-50767B	Palbociclib dihydrochloride	Inhibitor	/	Unkown

Clinical Phase

Bioactive Molecules (32)

Art. -Nr.	Produktname	Wirkung	Reinheit	Phase
HY-10580	GSK 3 Inhibitor IX	Inhibitor	99.73%	Phase 4
HY-114338A	Dalpiciclib hydrochloride	Inhibitor	99.41%	Phase 4
HY-122620	Rafutrombopag (tautomerism)	Agonist	98.33%	Phase 4
HY-145589	Rafutrombopag	Agonist	95.29%	Phase 4
HY-112272A	Lerociclib dihydrochloride	Inhibitor	98.51%	Phase 3
HY-112272	Lerociclib	Inhibitor	96.42%	Phase 3
HY-175538	USP10-IN-4	Inhibitor	/	Phase 3
HY-10005	Flavopiridol	Inhibitor	99.72%	Phase 2
HY-101563	GSK3326595		99.83%	Phase 2
HY-103712A	Samuraciclib hydrochloride	Inhibitor	99.98%	Phase 2
HY-50940	AT7519	Inhibitor	99.69%	Phase 2
HY-10006	Flavopiridol Hydrochloride	Inhibitor	99.73%	Phase 2
HY-137478	KB-0742	Inhibitor	99.63%	Phase 2
HY-137478A	KB-0742 dihydrochloride	Inhibitor	98.77%	Phase 2
HY-10424	Milciclib	Inhibitor	99.89%	Phase 2
HY-103712	Samuraciclib	Inhibitor	99.55%	Phase 2
HY-103712B	Samuraciclib hydrochloride dihydrate	Inhibitor	99.90%	Phase 2
HY-50943	AT7519 Hydrochloride	Inhibitor	99.16%	Phase 2
HY-103712C	Samuraciclib hydrochloride hydrate	Inhibitor	99.88%	Phase 2
HY-50940A	AT7519 TFA	Inhibitor	99.75%	Phase 2
HY-16559A	Riviciclib	Inhibitor	/	Phase 2
HY-10008	SNS-032	Inhibitor	99.91%	Phase 1
HY-10012	AZD-5438	Inhibitor	99.91%	Phase 1
HY-10014	R547	Inhibitor	99.57%	Phase 1
HY-11001	PHA-793887	Inhibitor	99.25%	Phase 1
HY-15504	RGB-286638	Inhibitor	99.67%	Phase 1
HY-12624	Narazaciclib	Inhibitor	98.66%	Phase 1
HY-12422	Voruciclib	Inhibitor	99.76%	Phase 1
HY-111361	FN-1501	Inhibitor	98.72%	Phase 1
HY-15504A	RGB-286638 free base	Inhibitor	98.09%	Phase 1
HY-12422A	Voruciclib hydrochloride	Inhibitor	99.26%	Phase 1
HY-182468	OP-3136		99.90%	Phase 1

Pre-clinical Phase

Bioactive Molecules (167)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-103248	Toyocamycin	Inhibitor	99.27%	Unkown
HY-10329	JNJ-7706621	Inhibitor	99.39%	Unkown
HY-15339	CVT-313	Inhibitor	99.90%	Unkown
HY-114177	Ebvaciclib	Inhibitor	99.98%	Unkown
HY-136250	BSJ-03-204	Inhibitor	99.76%	Unkown
HY-116035	Nimbolide	Inhibitor	99.79%	Unkown
HY-122609	XO44		99.73%	Unkown
HY-138946	XY028-140	Inhibitor	98.52%	Unkown
HY-18299A	Purvalanol A	Inhibitor	98.61%	Unkown
HY-15275	BMS-265246	Inhibitor	99.59%	Unkown
HY-N0404	Sinigrin	Inhibitor	99.97%	Unkown
HY-13914	Roniciclib	Inhibitor	98.00%	Unkown
HY-136252	BSJ-04-132	Inhibitor	99.07%	Unkown
HY-15878	LDC000067	Inhibitor	99.00%	Unkown
HY-18629	SU9516	Inhibitor	99.85%	Unkown
HY-11009	CGP60474	Inhibitor	98.90%	Unkown
HY-12445	Asnuciclib	Inhibitor	99.76%	Unkown
HY-N0805	Alisol B 23-acetate	Inhibitor	99.65%	Unkown
HY-15569	NU6102	Inhibitor	99.23%	Unkown
HY-128669	Abemaciclib metabolite M2	Inhibitor	99.75%	Unkown
HY-126534A	Abemaciclib metabolite M18 hydrochloride	Inhibitor	98.18%	Unkown
HY-168664	CPD-39	Degrader	98.06%	Unkown
HY-16559	Riviciclib hydrochloride		99.08%	Unkown
HY-163786	PROTAC CDK4/6 degrader 1	Degrader	98.88%	Unkown
HY-13266A	BS-181 hydrochloride	Inhibitor	99.93%	Unkown
HY-119940	MC180295	Inhibitor	98.07%	Unkown
HY-N1431	Tabersonine	Inhibitor	98.13%	Unkown
HY-147007	β-catenin-IN-3	Inhibitor	95.64%	Unkown
HY-129336	Abemaciclib metabolite M20	Inhibitor	95.92%	Unkown
HY-129180	XY028-133	Inhibitor	99.07%	Unkown
HY-100624	Ryuvidine	Inhibitor	99.23%	Unkown
HY-151071	TMX-3013	Inhibitor	98.02%	Unkown
HY-15889	AMG 925	Inhibitor	99.02%	Unkown
HY-126534	Abemaciclib metabolite M18	Inhibitor	98.01%	Unkown
HY-50767S	Palbociclib-d8	Inhibitor	99.84%	Unkown
HY-168660	CPD-10	Degrader	98.59%	Unkown
HY-144995	BSJ-02-162	Inhibitor	98.07%	Unkown
HY-150280	Ironomycin	Inhibitor	99.85%	Unkown
HY-163640	CDK4 degrader 1	Degrader	99.83%	Unkown
HY-148214	CDK2/4/6-IN-2	Inhibitor	98.20%	Unkown
HY-151069	TMX-2039	Inhibitor	99.42%	Unkown
HY-142076	CDK4/6-IN-15	Inhibitor	99.32%	Unkown
HY-164129	CDK4-IN-3	Inhibitor	98.07%	Unkown
HY-152263	HEMTAC CDK4/6 degrader 1	Inhibitor	98.18%	Unkown
HY-N7045	Isosilybin B	Inhibitor	99.32%	Unkown
HY-148061	DB1113		99.86%	Unkown
HY-153894	SRX3177	Inhibitor	99.33%	Unkown
HY-107419	NU6140	Inhibitor	99.53%	Unkown
HY-148062	RSS0680		99.85%	Unkown
HY-114339	CDK4/6-IN-2	Inhibitor	99.67%	Unkown
HY-16942	Damulin B	Inhibitor	≥95.0%	Unkown
HY-123045	PNU-292137	Inhibitor	99.95%	Unkown
HY-100429	CAN508	Inhibitor	99.71%	Unkown
HY-126251	CDK9-IN-7	Inhibitor	98.05%	Unkown
HY-136726	CGP-82996	Inhibitor	98.12%	Unkown
HY-155787	SHR5428	Inhibitor	99.80%	Unkown
HY-112822	ON-013100	Inhibitor	99.66%	Unkown
HY-45661	Inixaciclib	Inhibitor	99.93%	Unkown
HY-103380	NSC 625987	Inhibitor	98.01%	Unkown
HY-119715	AG-012986	Inhibitor	99.78%	Unkown
HY-129336S	Abemaciclib metabolite M20-d8	Inhibitor	99.26%	Unkown
HY-108420	INK4C-IN-2	Activator	98.10%	Unkown
HY-168996	LA-CB1	Degrader	98.20%	Unkown
HY-115992	CDK4/6-IN-9	Inhibitor	99.46%	Unkown
HY-112328	Fascaplysin	Inhibitor	95.64%	Unkown
HY-142696A	CDK6/PIM1-IN-1 hydrochloride	Inhibitor	99.38%	Unkown
HY-146213	CDK4/6-IN-12	Inhibitor	99.76%	Unkown
HY-179688	PROTAC CDK2/4 Degrader-1	Degrader	/	Unkown
HY-13266	BS-181	Inhibitor	98.10%	Unkown
HY-148365	NecroIr1	Inhibitor	98.53%	Unkown
HY-185121	PROTAC CDK2/4/6 Degrader-2	Degrader	97.22%	Unkown
HY-115909	ZDLD20	Inhibitor	99.84%	Unkown
HY-168440	Aurora-A ligand 1	Ligand	98.75%	Unkown
HY-148366	NecroIr2	Inhibitor	98.02%	Unkown
HY-123535	P18IN003	Activator	99.49%	Unkown
HY-201330	GDC-4198	Inhibitor	/	Unkown
HY-112243A	Cimpuciclib tosylate	Inhibitor	99.65%	Unkown
HY-112346	RGB-286147	Inhibitor	98.60%	Unkown
HY-164906	TMX-2138	Degrader	/	Unkown
HY-15889A	AMG 925 (HCl)	Inhibitor	/	Unkown
HY-112418	CDK4/6-IN-18	Inhibitor	98.9%	Unkown
HY-147125	DDO-6600	Inhibitor	99.2%	Unkown
HY-142696	CDK6/PIM1-IN-1	Inhibitor	/	Unkown
HY-153556	GW297361	Inhibitor	98.13%	Unkown
HY-N2423	Sinigrin hydrate	Inhibitor	99.92%	Unkown
HY-112450	Olomoucine II	Inhibitor	98.0%	Unkown
HY-111207	CA224	Inhibitor	99.94%	Unkown
HY-112243	Cimpuciclib	Inhibitor	/	Unkown
HY-126244	CDK4/6-IN-3	Inhibitor	/	Unkown
HY-150609	SHP2/CDK4-IN-1	Inhibitor	/	Unkown
HY-159155	CDK2/4-IN-1	Inhibitor	/	Unkown
HY-180912	HS-36	Inhibitor	/	Unkown
HY-171656	G721-0282	Inhibitor	99.96%	Unkown
HY-178168	ARUK2010694	Inhibitor	/	Unkown
HY-146276	CDK/HDAC-IN-2	Inhibitor	/	Unkown
HY-115993	CDK4/6-IN-10	Inhibitor	/	Unkown
HY-162530	CDK4/6-IN-20	Inhibitor	/	Unkown
HY-115904	FLT3/CDK4-IN-1	Inhibitor	/	Unkown
HY-114338B	Dalpiciclib isethionate	Inhibitor	/	Unkown
HY-134303	CST651	Degrader	/	Unkown
HY-160941	CDK2-IN-29	Inhibitor	/	Unkown
HY-163856	CDK7-IN-30	Inhibitor	/	Unkown
HY-178112	CDK2-IN-47	Inhibitor	/	Unkown
HY-128491	UNC10112785	Inhibitor	/	Unkown
HY-143258	CDK4/6-IN-8	Inhibitor	/	Unkown
HY-183297	CDK4-IN-5	Inhibitor	/	Unkown
HY-179375	LCI133	Inhibitor	/	Unkown
HY-184418	CDK4-IN-6	Inhibitor	/	Unkown
HY-183854	AG-12286	Inhibitor	/	Unkown
HY-171740	CDK4-IN-4	Inhibitor	/	Unkown
HY-123859	SR-2890	Inhibitor	/	Unkown
HY-123034	CDKI-83	Inhibitor	/	Unkown
HY-178171	ARUK2010489	Inhibitor	96.64%	Unkown
HY-182470	AG-012986 dihydrochloride	Inhibitor	/	Unkown
HY-168444	CDK4/6-IN-23	Inhibitor	/	Unkown
HY-171481	Thio-acridone	Inhibitor	/	Unkown
HY-146253	CDK1/2/4-IN-1	Inhibitor	/	Unkown
HY-179151	CDK4/6-IN-26	Inhibitor	/	Unkown
HY-143257	CDK4/6-IN-7	Inhibitor	/	Unkown
HY-163787	YY173	Inhibitor	/	Unkown
HY-182044	MRTX849-amide-C4-(o)-carborane	Inhibitor	/	Unkown
HY-181062	VWK147	Inhibitor	/	Unkown
HY-W1047040	CDK2/4 ligand 1	Inhibitor	/	Unkown
HY-151898	CDK4/6-IN-14	Inhibitor	/	Unkown
HY-115908	ZDLD13	Inhibitor	/	Unkown
HY-171826	PROTAC CDK2/4/6 Degrader-1	Inhibitor	/	Unkown
HY-141685	3-Methylthienyl-carbonyl-JNJ-7706621	Inhibitor	/	Unkown
HY-176365	Palbociclib-C4-Boc	Inhibitor	/	Unkown
HY-170651	CDK4/6/HDAC-IN-1	Inhibitor	/	Unkown
HY-170992	Autophagy agonist-1	Inhibitor	/	Unkown
HY-172128	NUAK1-IN-2	Inhibitor	/	Unkown
HY-172127	NUAK1-IN-1	Inhibitor	/	Unkown
HY-162529	CDK4/6-IN-19	Inhibitor	/	Unkown
HY-164376A	CDK4/6-IN-21 maleate	Inhibitor	/	Unkown
HY-164376	CDK4/6-IN-21	Inhibitor	/	Unkown
HY-182734	BMS-357075	Inhibitor	/	Unkown
HY-182986	LS-Q2	Inhibitor	/	Unkown
HY-181501	CDK2/4/6-IN-3	Inhibitor	/	Unkown
HY-147409	Ulecaciclib	Inhibitor	/	Unkown
HY-115942	Anticancer agent 29	Inhibitor	/	Unkown
HY-183771	CDK4/6-IN-28	Inhibitor	/	Unkown
HY-185487	CDK4/6-IN-27	Inhibitor	/	Unkown
HY-183571	JD128	Inhibitor	/	Unkown
HY-155602	CDK2-IN-18	Inhibitor	/	Unkown
HY-137478B	KB-0742 hydrochloride	Inhibitor	/	Unkown
HY-182752	CDK1-IN-9	Inhibitor	/	Unkown
HY-172234	PF-06842874	Inhibitor	/	Unkown
HY-182447	Contragestazol	Inhibitor	/	Unkown
HY-153336	PRT3645	Inhibitor	/	Unkown
HY-170815	CDK4/9-IN-1	Inhibitor	/	Unkown
HY-148213	CDK2/4/6-IN-1	Inhibitor	/	Unkown
HY-176718	VEGFR-2-IN-69	Inhibitor	/	Unkown
HY-178516	PROTAC CDK4/6/9 degrader 2	Degrader	/	Unkown
HY-111932	Indirubin-5-sulfonate	Inhibitor	/	Unkown
HY-184444	CDK4-IN-7	Inhibitor	/	Unkown
HY-172198	GSK3-IN-10	Inhibitor	/	Unkown
HY-173237	CDK4/6/BRD4-IN-1	Inhibitor	/	Unkown
HY-153088	CDK4/6-IN-16	Inhibitor	/	Unkown
HY-162619	CDK9-IN-33	Inhibitor	/	Unkown
HY-178452	PROTAC CDK4/6/9 degrader 1	Degrader	/	Unkown
HY-102088	P18IN011	Inhibitor	/	Unkown
HY-N11852	Momilactone B	Inhibitor	/	Unkown
HY-173172	MG-002	Inhibitor	/	Unkown
HY-118447	RO0505124		/	Unkown
HY-11001A	PHA-793887 hydrochloride	Inhibitor	/	Unkown
HY-N1431A	Tabersonine hydrochloride	Inhibitor	98.55%	Unkown
HY-183529	Antitrypanosomal agent 31	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CDK4	VGNC	VGNC:83524
Rattus norvegicus	CDK4	RGD	RGD:621120
Mus musculus	CDK4	MGD	MGI:88357
Macaca mulatta	CDK4	VGNC	VGNC:70980
Canis familiaris	CDK4	VGNC	VGNC:39054
Others	CDK4	NCBI