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3'-OH

" in MedChemExpress (MCE) Product Catalog:

1901

Inhibitors & Agonists

26

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117

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892

Peptides

118

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Products

1

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160

Isotope-Labeled Compounds

146

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31

Oligonucleotides

3

GMP Molecules

Cat. No. Product Name Target Research Area
  • HY-136432

    Mc-GGFG-PAB-OH

    ADC Linker Cancer
    Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
  • HY-P4486

    Pro-Gly-Pro

    Drug Derivative Others
    H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia .
  • HY-P10069

    Drug Intermediate ADC Linker Others
    Ac-pSar12-OH is a water-soluble polymer of the polysarcosine class and can be used as a linker. Ac-pSar12-OH is a linear polypeptide derivative composed of 12 arginine units. Ac-pSar12-OH N-terminus is modified with an acetyl group, while the C-terminus retains a free hydroxyl group, which can help enhance the stability of the polypeptide .
  • HY-P4648

    Trp-Trp-Trp

    Bacterial Infection
    H-Trp-Trp-Trp-OH (Trp-Trp-Trp) is a tripeptide consisting of tryptophan. H-Trp-Trp-Trp-OH has antibacterial activity. H-Trp-Trp-Trp-OH is a human bitter taste receptor hTAS2R14 agonist .
  • HY-P4322
    H-Ile-Lys-Val-Ala-Val-OH
    1 Publications Verification

    ERK Akt Neurological Disease Cancer
    H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adhesion, neurite outgrowth, and tumor growth. H-Ile-Lys-Val-Ala-Val-OH stimulates BMMSC population growth and proliferation by activating MAPK/ERK1/2 and PI3K/Akt signalling pathways .
  • HY-41121
    Boc-L-Ala-OH
    1 Publications Verification

    Boc-Ala-OH

    Amino Acid Derivatives Cancer
    Boc-L-Ala-OH (Boc-Ala-OH) is a single N-protected amino acid ligand and a protected L-alanine derivative. Boc-L-Ala-OH promotes Pd (II)-catalyzed enantioselective C-H alkenylation and kinetic resolution. Boc-L-Ala-OH serves as a coupling reagent for the synthesis of liver-targeted glycogen phosphorylase inhibitors and P6A metabolites, and also acts as a negative control in synthesis studies of betulinic acid amino acid esters. Boc-L-Ala-OH is applicable to research on epidermoid squamous cell carcinoma .
  • HY-W010836

    Amino Acid Derivatives Others
    Fmoc-Bip(4,4')-OH is an alanine derivative .
  • HY-66026

    Amino Acid Derivatives Others
    Fmoc-Lys(Me)3-OH Chloride is a lysine derivative .
  • HY-P4531

    Amino Acid Derivatives Neurological Disease
    H-Ser-Tyr-OH is a dipeptide. H-Ser-Tyr-OH can form a copper(II) complex .
  • HY-P4846
    Ac-Pro-Gly-Pro-OH
    2 Publications Verification

    CXCR Apoptosis IFNAR TNF Receptor Interleukin Related Infection Inflammation/Immunology
    Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and acts as a CXCR2 agonist . Ac-Pro-Gly-Pro-OH exerts bactericidal activity by generating hydrogen peroxide, inhibits pulmonary inflammation, and reduces immune cell apoptosis (apoptosis). Ac-Pro-Gly-Pro-OH promotes the production of IFN-γ and inhibits the production of TNF-α and IL-6 in leukocytes. Ac-Pro-Gly-Pro-OH increases the survival rate of mice in sepsis models, enhances the bactericidal activity of neutrophils, acts as a neutrophil chemoattractant, induces neutrophil polarization, and regulates inflammatory and repair processes. Ac-Pro-Gly-Pro-OH induces chronic inflammation and tissue remodeling through sustained action. Ac-Pro-Gly-Pro-OH is released via alkaline hydrolysis of corneal proteins in alkali-injured eyes, thereby driving the early infiltration of neutrophils into the cornea. Ac-Pro-Gly-Pro-OH is applicable to research related to sepsis, chronic obstructive pulmonary disease, cystic fibrosis, bronchiolitis obliterans syndrome, severe asthma, idiopathic pulmonary fibrosis, and corneal ulcer .
  • HY-P4420

    Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    H-Lys-Trp-OH (KW) is an ACE inhibitory peptide with an IC50 of 7.8 μM .
  • HY-P4509

    Ser-Phe

    Peptides Others
    H-Ser-Phe-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4424

    Met-Arg

    Peptides Others
    H-Met-Arg-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-W007618

    Amino Acid Derivatives Biochemical Assay Reagents Drug Intermediate Others
    Boc-Lys-OH is an amino acid derivative. Boc-Lys-OH plays a key role in peptide synthesis and redox activity research .
  • HY-145779A

    H-γ-Glu-Met-OH TFA; γ-Glu-Met TFA

    Peptides Metabolic Disease
    H-Glu(Met-OH)-OH TFA (γ-Glu-Met TFA) could induce oxidation of hydroxyl radical .
  • HY-P4554

    Phe-Arg

    Endogenous Metabolite Metabolic Disease
    H-Phe-Arg-OH is a dipeptide containing phenylalanine and arginine. H-Phe-Arg-OH can be separated from Bradykinin (HY-P0206) through Angiotensin-converting enzyme (ACE, HY-P2983). H-Phe-Arg-OH can be used for metabolic research .
  • HY-P4641

    Trp-Phe

    Angiotensin-converting Enzyme (ACE) Endothelin Receptor Cardiovascular Disease
    H-Trp-Phe-OH (Trp-Phe) is an ACE inhibitor and endothelial function regulator, with an ACE IC50 of 0.318 mg/mL. H-Trp-Phe-OH increases nitric oxide concentration, reduces endothelin-1 (ET-1) levels, and reverses norepinephrine-mediated endothelial cell dysfunction. H-Trp-Phe-OH exhibits antihypertensive activity. H-Trp-Phe-OH can be used in studies related to hypertension and atherosclerosis .
  • HY-P4294

    Gly-Pro-Gly

    Amino Acid Derivatives Others
    H-Gly-Pro-Gly-OH is a tripeptide containing glycine and proline. H-Gly-Pro-Gly-OH can be used for the synthesis of other polypeptides, such as (Pro Gly Gly)n .
  • HY-P4232

    Amino Acid Derivatives Others
    H-Gly-Arg-Ala-Asp-Ser-Pro-OH (GRADSP) is a negative control peptide of GRGDSPK .
  • HY-P4545

    Angiotensin Receptor Others
    Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .
  • HY-P4478

    Peptides Others
    H-Phe-Met-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4415

    Peptides Others
    H-Lys-Gly-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4321

    Peptides Others
    H-Ile-His-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4434

    Peptides Others
    H-Met-Glu-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-W142161

    Fmoc-MeHis(Trt)-OH

    Amino Acid Derivatives Others
    Fmoc-N-Me-His(Trt)-OH (Fmoc-MeHis(Trt)-OH) is an Amino acid derivative containing a carboxyl group. Fmoc-N-Me-His(Trt)-OH can be used for the synthesis of Fmoc-MeHis (Trt)-Leu-OH and N-methyl peptides .
  • HY-P4550

    Endogenous Metabolite Metabolic Disease
    H-Hyp-Gly-OH is a dipeptide containing hydroxyproline and glycine. H-Hyp-Gly-OH promotes the growth of mouse primary fibroblasts on collagen gel. H-Hyp-Gly-OH has potential applications in improving skin by ingesting hydrolyzed collagen. H-Hyp-Gly-OH can be used for metabolic research .
  • HY-W040067

    Amino Acid Derivatives Others
    Boc-Arg(NO2)-OH is an arginine derivative .
  • HY-W010811

    Amino Acid Derivatives Others
    Fmoc-Phe(F5)-OH is a phenylalanine derivative .
  • HY-P4383

    Peptides Others
    H-Leu-Leu-Ala-OH is a tripeptide composed of two L-leucine units joined to L-alanine by a peptide linkage. H-Leu-Leu-Ala-OH shows antioxidant activities .
  • HY-P4231

    Gly-Ala-Hyp

    Peptides Others
    H-Gly-Ala-Hyp-OH is a collagen tripeptide fragment .
  • HY-P4286

    Peptides Cancer
    H-Gly-Leu-Phe-OH (GLF), an immunostimulatory tripeptide derived from α-lactalbumin, inhibits anticancer agent Etoposide-induced alopecia, epidermal thickening, and thinning of the adipocyte layer .
  • HY-P4317

    Peptides Others
    H-His-Trp-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4226

    Peptides Others
    H-Glu-Val-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4624

    Peptides Others
    H-Thr-Met-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4512

    Peptides Others
    H-Ser-Ser-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4511

    H-Ser-Leu-OH; Ser-Leu

    Peptides Infection
    Serylleucine (H-Ser-Leu-OH) is a dipeptide. Serylleucine's core 1 o-glycosylated peptide (SLC1G) can be detected in urine as a metabolite and is a biomarker in TB studies .
  • HY-P4472

    Phe-Asp

    Peptides Others
    H-Phe-Asp-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-145779

    H-γ-Glu-Met-OH; γ-Glu-Met

    Dipeptidyl Peptidase Metabolic Disease
    H-Glu(Met-OH)-OH (H-γ-Glu-Met-OH; γ-Glu-Met) is a DPP-IV inhibitor with an IC50 of 2.11 mM. H-Glu(Met-OH)-OH binds to DPP-IV’s active site to block substrate binding. H-Glu(Met-OH)-OH can be used for the research of type 2 diabetes .
  • HY-W010770

    Amino Acid Derivatives Others
    Fmoc-Thr[PO(OBzl)OH]-OH is a threonine derivative .
  • HY-W077219

    Boc-Arg(Mtr)-OH

    Amino Acid Derivatives Others
    Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .
  • HY-78843

    Amino Acid Derivatives Others
    Boc-Bip(4,4')-OH is a phenylalanine derivative .
  • HY-66025

    Amino Acid Derivatives Others
    Fmoc-Lys(Me)2-OH HCl is a lysine derivative .
  • HY-P4483

    Peptides Others
    H-Pro-Arg-OH is a dipeptide composed of proline and arginine.
  • HY-P4659

    Peptides Others
    H-Val-Arg-OH is a dipeptide consisting of valine and arginine, used in biochemical research .
  • HY-P4431

    Amino Acid Derivatives Others
    H-Met-Asp-OH is a dipeptide containing methionine and aspartic acid, which can be used for the synthesis of polypeptides .
  • HY-P4551

    N-Benzoyl-Gly-His-Leu

    Angiotensin-converting Enzyme (ACE) Amino Acid Derivatives Cardiovascular Disease
    Hippuryl-His-Leu-OH (N-Benzoyl-Gly-His-Leu) is a specific substrate for angiotensin-converting enzyme (ACE I) and a molecular tool used for ACE activity detection in in vitro experiments. Hippuryl-His-Leu-OH is hydrolyzed by ACE through competitive binding. Under ACE catalysis, Hippuryl-His-Leu-OH undergoes hydrolysis to produce hippuric acid (HA). The amount of HA produced can be used to quantitatively assess ACE activity or screen for ACE inhibitors. The released His-Leu can also react with o-phthalaldehyde or Fluorescamine (HY-D0715) for fluorescence detection. Hippuryl-His-Leu-OH can be applied to the in vitro screening of ACE inhibitors for hypertension and cardiovascular diseases, and is also used in the study of ACE activity changes in physiological and pathological processes such as renal compensatory hypertrophy .
  • HY-P4485

    Peptides Others
    H-Pro-Asn-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4473

    Peptides Others
    H-Phe-Ile-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4374

    Peptides Others
    H-Leu-Asn-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
  • HY-P4499

    Peptides Others
    H-Ser-Ala-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

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