274 Results for "

-cyclodextrin

" in MedChemExpress (MCE) Product Catalog:
Products (274)

274 Results for "-cyclodextrin" in MCE Product Catalog:

11
11 Cited Publications
Art. -Nr.: HY-107201
CAS. Nr.: 7585-39-9
Reinheit:  99.95%
Synonyms: Betadex
Target:  

Influenza Virus

Forschungsgebiete:  

Infection

β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.
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2
2 Cited Publications
Art. -Nr.: HY-B1513
CAS. Nr.: 10016-20-3
α-Cyclodextrin (α-CD) is a soluble fiber derived from corn. α-Cyclodextrin can deplete sphingolipids and phospholipids from cell membranes. α-Cyclodextrin interacts with tubulin. α-Cyclodextrin improves defenses against SARS-CoV-2 infection. α-Cyclodextrin enhances the anticancer efficacy of Crcumin (HY-N0005) against breast, lung and cervical cancer. α-Cyclodextrin has beneficial effects on body weight and blood lipids .
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Art. -Nr.: HY-W040040
CAS. Nr.: 17465-86-0
γ-Cyclodextrin is an orally active cyclic oligosaccharide composed of eight glucose molecules, which can be formed by bacteria digesting starch. γ-Cyclodextrin can form water-soluble inclusion complexes with a variety of poorly soluble compounds and is widely used in fields such as pharmacy and food. In addition, γ-Cyclodextrin has good safety .
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402
402 Publications Verification
Art. -Nr.: HY-14648C
CAS. Nr.: 50-02-2
Reinheit:  ≥98.0%
Synonyms: Dexamethasone cyclodextrin complex
Dexamethasone (Hexadecadrol) Water Soluble is a water-soluble form of Dexamethasone (HY-14648). Dexamethasone is a glucocorticoid receptor agonist, apoptosis inducer, and a common disease inducer in experimental animals. It can be used to construct models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has the potential to be used in COVID-19 research .(Sale size is the weight of dexamethasone)
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167
167 Cited Publications
Art. -Nr.: HY-17031
CAS. Nr.: 182410-00-0
Synonyms: Sulfobutylether-β-cyclodextrin
SBE-β-CD is a sulfobutylether β-cyclodextrin derivative used as an excipient or a formulating agent to increase the solubility of poorly soluble agents .
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120
120 Cited Publications
Art. -Nr.: HY-101461
CAS. Nr.: 128446-36-6
Reinheit:  99.95%
Synonyms: Methyl-beta-cyclodextrin
Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent . Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis . Methyl-β-cyclodextrin blocks cell migrasome formation .
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95
95 Cited Publications
Art. -Nr.: HY-N0322A
Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .
(Note: This product is a mixture of Cholesterol and Methyl-β-cyclodextrin. The product specifications below only indicate the effective content of Cholesterol.)
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33
33 Cited Publications
Art. -Nr.: HY-101103
CAS. Nr.: 128446-35-5
Reinheit:  99.74%
Synonyms: (2-Hydroxypropyl)-β-cyclodextrin
HP-β-CD ((2-Hydroxypropyl)-β-cyclodextrin) is a widely used drug delivery vehicle to improve the stability and bioavailability.
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32
32 Cited Publications
Art. -Nr.: HY-P0023
CAS. Nr.: 161552-03-0
Target:  

Integrin

Forschungsgebiete:  

Cancer

Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Cyclo(-RGDfK) potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .
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32
32 Cited Publications
Art. -Nr.: HY-P0023A
CAS. Nr.: 500577-51-5
Target:  

Integrin

Forschungsgebiete:  

Cancer

Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM . Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .
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17
17 Cited Publications
Art. -Nr.: HY-12559
CAS. Nr.: 254435-95-5
Reinheit:  98.08%
Synonyms: Debio-025; DEB-025
Target:  

Cyclophilin HCV

Forschungsgebiete:  

Infection

Alisporivir (Debio-025) is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity.
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8
8 Cited Publications
Art. -Nr.: HY-P1934
CAS. Nr.: 14705-60-3
Synonyms: Cyclo(phenylalanylprolyl); A-64863
Forschungsgebiete:  

Infection

Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that specifically interacts with RIG-I, inhibiting RIG-I polyubiquitination, suppressing IRF-3 activation, and reducing type I interferon production. Cyclo(Phe-Pro) enhances susceptibility to HCV and influenza virus and also alleviates plant aluminum toxicity stress. The mechanism of Cyclo(Phe-Pro) involves the regulation of host immune signaling pathways, bacterial virulence gene expression, and plant antioxidant systems, making it a promising candidate for research in viral infections, bacterial virulence regulation, and agricultural stress resistance .
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7
7 Cited Publications
Art. -Nr.: HY-W019711
CAS. Nr.: 14371-10-9
trans-Cinnamaldehyde can be used to prepare highly polyfunctionalized furan ring by reaction of alkyl isocyanides with dialkyl acetylenedicarboxylate . trans-Cinnamaldehyde can be used to synthesize trans-cinnamaldehyde -β-cyclodextrin complex, an antimicrobial edible coating that increases the shelf life of fresh-cut fruits .
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4
4 Cited Publications
Art. -Nr.: HY-100563A
CAS. Nr.: 217099-14-4
Reinheit:  99.83%
Target:  

Integrin

Forschungsgebiete:  

Cancer

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.
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4
4 Cited Publications
Art. -Nr.: HY-100563
CAS. Nr.: 250612-42-1
Reinheit:  99.92%
Target:  

Integrin

Forschungsgebiete:  

Cancer

Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.
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4
4 Cited Publications
Art. -Nr.: HY-12378
CAS. Nr.: 136553-81-6
Reinheit:  99.82%
Target:  

Endothelin Receptor

Forschungsgebiete:  

Cardiovascular Disease

BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension .
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4
4 Cited Publications
Art. -Nr.: HY-P1674A
CAS. Nr.: 3053070-05-3
Synonyms: POL7080 TFA
Target:  

Bacterial Antibiotic

Forschungsgebiete:  

Infection

Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC50 and MIC90 values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance .
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3
3 Cited Publications
Art. -Nr.: HY-P0257
CAS. Nr.: 170809-51-5
Target:  

CRFR

Forschungsgebiete:  

Neurological Disease

Astressin is a potent corticotropin releasing factor (CRF) antagonist.
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2
2 Cited Publications
Art. -Nr.: HY-P2300
CAS. Nr.: 862772-11-0
Synonyms: Cyclo(RGDfC)
Target:  

Integrin

Forschungsgebiete:  

Cancer

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors .
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2
2 Cited Publications
Art. -Nr.: HY-B1007
CAS. Nr.: 149-16-6
Target:  

Sodium Channel

Forschungsgebiete:  

Neurological Disease

Butacaine is a reversible nerve conduction blocker. Butacaine acts on the nervous system and nerve fibers, can cause both sensory and motor paralysis. Butacaine inhibits the NavBh currents. Butacaine can form inclusion complexes with α-cyclodextrin (α-CD) and β-cyclodextrin (β-CD). Butacaine is commonly used as a negative control for other local anesthetics .
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