BRD4 - bromodomain containing 4 Gene

Species: Felis catus

Gene Type: protein coding
Gene ID: 101100035

BRD4 Products (7)

mRNA Protein Name
XM_023246615.2 XP_023102383.1 bromodomain-containing protein 4 isoform X1
XM_023246612.2 XP_023102380.1 bromodomain-containing protein 4 isoform X1
XM_023246610.2 XP_023102378.1 bromodomain-containing protein 4 isoform X1
XM_045047402.1 XP_044903337.1 bromodomain-containing protein 4 isoform X3
XM_023246624.2 XP_023102392.1 bromodomain-containing protein 4 isoform X4
XM_023246621.2 XP_023102389.1 bromodomain-containing protein 4 isoform X2
XM_045047406.1 XP_044903341.1 bromodomain-containing protein 4 isoform X4

BRD4 Protein Structure

Bromo_Brdt_I_like

Bromo_Brdt_I_like: cd05497 (57 - 163)

Bromo_Brdt_II_like

Bromo_Brdt_II_like: cd05498 (352 - 453)

BET

BET: pfam17035 (608 - 672)

TPH

TPH: cl38442 (1259 - 1302)

BRD4_CDT

BRD4_CDT: pfam17105 (1350 - 1393)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1394 a.a.
Protein Preferred Names Protein Names

bromodomain-containing protein 4

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Phase
HY-12863 Pelabresib Inhibitor 99.95% Phase 3
HY-111916 ODM-207 Inhibitor 99.58% Phase 2
HY-13030 (+)-JQ-1 Inhibitor 99.91% Phase 1
HY-112090 ABBV-744 Inhibitor 99.97% Phase 1
HY-100015 Mivebresib Inhibitor 99.29% Phase 1
HY-117286 (S)-JQ-35 Inhibitor 99.46% Phase 1
HY-117491 BRD4 Inhibitor-10 Inhibitor 99.52% Phase 1

Pre-clinical Phase

Bioactive Molecules (231)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100972 ARV-771 Degrader 99.87% Unkown
HY-101838 dBET1 Inhibitor 99.24% Unkown
HY-78695 JQ-1 carboxylic acid Inhibitor 99.69% Unkown
HY-129937A GNE-987 Inhibitor 99.98% Unkown
HY-136570 GSK778 Inhibitor 99.14% Unkown
HY-122826 ZXH-3-26 Inhibitor 99.53% Unkown
HY-14443 XMD8-92 Inhibitor 99.48% Unkown
HY-100482 CPI-637 Inhibitor 99.94% Unkown
HY-176521 AR/BRD4 RIPTAC-1 Inhibitor 98.65% Unkown
HY-114305 A1874 Inhibitor 99.77% Unkown
HY-123941 FKBP12 PROTAC dTAG-7 Inhibitor 99.47% Unkown
HY-136571 GSK046 Inhibitor 99.70% Unkown
HY-120028 GNE-207 Inhibitor 99.94% Unkown
HY-107443 I-BET762 carboxylic acid Inhibitor 99.55% Unkown
HY-112609 QCA570 Inhibitor 99.30% Unkown
HY-114204 GSK8814 Inhibitor 99.80% Unkown
HY-123844 dBET57 Inhibitor 99.94% Unkown
HY-110374 NVS-CECR2-1 Inhibitor 99.40% Unkown
HY-141438 SIM1 Degrader 99.47% Unkown
HY-160528 IBG3 Inhibitor 98.53% Unkown
HY-153385 TMX1 Degrader 99.57% Unkown
HY-13960 GSK1324726A Inhibitor 99.92% Unkown
HY-153459 IBG1 Degrader 99.88% Unkown
HY-101146 SF2523 Inhibitor 99.34% Unkown
HY-125232 MS645 98.0% Unkown
HY-138563 GSK973 Inhibitor 99.97% Unkown
HY-126428 ZL0580 Modulator 99.42% Unkown
HY-156820 HLDA-221 99.24% Unkown
HY-101519 BETd-260 Inhibitor 99.68% Unkown
HY-133736 PROTAC BRD4 Degrader-5-CO-PEG3-N3 99.73% Unkown
HY-130622 LT052 Inhibitor 98.02% Unkown
HY-156828 MMH2 Degrader 98.95% Unkown
HY-158031 PLK1/BRD4-IN-5 Inhibitor 98.80% Unkown
HY-163638 BRD4 degrader-1 Degrader 99.85% Unkown
HY-112429 HJB97 Inhibitor 99.12% Unkown
HY-129917 KB02-JQ1 Inhibitor 99.10% Unkown
HY-151594 iBRD4-BD1 Inhibitor 98.77% Unkown
HY-112376 MZP-54 Inhibitor 98.03% Unkown
HY-136857 BRD4 degrader-3 Degrader 99.43% Unkown
HY-114504 RVX-297 Inhibitor 95.00% Unkown
HY-174995 JQ-1-Azidopropylamine Degrader 99.5700% Unkown
HY-156827 MMH1 Degrader 99.83% Unkown
HY-158764 PROTAC BET Degrader-12 Degrader 98.10% Unkown
HY-103632 PROTAC BRD9 Degrader-1 Inhibitor 99.16% Unkown
HY-129939 BET-IN-31 Inhibitor 99.85% Unkown
HY-114407 TD-428 Inhibitor 98.81% Unkown
HY-148864 JQ1-TCO Inhibitor 99.95% Unkown
HY-153894 SRX3177 Inhibitor 99.33% Unkown
HY-114416 GS-626510 Inhibitor 99.46% Unkown
HY-129201 ZEN-2759 Inhibitor 99.51% Unkown
HY-133131 PROTAC BRD4 Degrader-1 Inhibitor 99.31% Unkown
HY-111102 FL-411 Inhibitor 99.05% Unkown
HY-120000 MS402 Inhibitor 98.36% Unkown
HY-112610 CF53 Inhibitor 99.81% Unkown
HY-161515 BRD4/NAMPT-IN-1 Inhibitor 99.45% Unkown
HY-148864A (Z)-JQ1-TCO Inhibitor 99.12% Unkown
HY-136920 CBP/p300-IN-8 Inhibitor 98.03% Unkown
HY-133737 GAL-02-221 Inhibitor 99.87% Unkown
HY-111875 SNIPER(BRD)-1 Inhibitor 99.68% Unkown
HY-131061 BET bromodomain inhibitor 1 Inhibitor 99.67% Unkown
HY-146208 BRD4 Inhibitor-20 Inhibitor 99.24% Unkown
HY-139148 UMB298 Inhibitor 99.28% Unkown
HY-145264 OARV-771 Inhibitor 98.77% Unkown
HY-111502 Y06036 Inhibitor 98.57% Unkown
HY-145260 BRD4/CK2-IN-1 Inhibitor 98.21% Unkown
HY-43723 PROTAC BET-binding moiety 2 Ligand 99.77% Unkown
HY-133136 PROTAC BRD4 Degrader-2 Inhibitor 98.30% Unkown
HY-146999 YM458 Inhibitor 99.16% Unkown
HY-163729 I-BET787 Inhibitor 99.88% Unkown
HY-110215 XD14 Inhibitor 95.02% Unkown
HY-107442 PROTAC BRD4-binding moiety 1 99.10% Unkown
HY-160558 PLK1/BRD4-IN-3 Inhibitor 98.55% Unkown
HY-138634 GNE-987 GSH linker-2 Inhibitor 99.48% Unkown
HY-101121 NI-42 Inhibitor 99.53% Unkown
HY-44103 Desmethyl-QCA276 Ligand 99.16% Unkown
HY-P10446 TAT-PiET-PROTAC Inhibitor 98.04% Unkown
HY-107425A cis-MZ 1 Control 99.8% Unkown
HY-100696 PNZ5 Inhibitor 99.61% Unkown
HY-103297 OXFBD02 Inhibitor 98.04% Unkown
HY-149100 PLK1-IN-6 Inhibitor / Unkown
HY-111503 Y06137 Inhibitor 99.90% Unkown
HY-132991 ML 2-14 Degrader 99.43% Unkown
HY-138632 PROTAC BRD4 Degrader linker conjugate-1 Degrader 98.98% Unkown
HY-142520 I-BET567 Inhibitor 99.49% Unkown
HY-161651 BRD4 ligand 6 / Unkown
HY-169358 L134 Inhibitor 99.37% Unkown
HY-135236 OXFBD04 Inhibitor 98.99% Unkown
HY-147046 ET-JQ1-OH Inhibitor / Unkown
HY-111977 ZEN-3219 Inhibitor 99.75% Unkown
HY-169355 TrimTAC1 Degrader / Unkown
HY-132941 CFT-2718 Degrader 99.87% Unkown
HY-107425B cis-MZ 1 hydrate 99.0% Unkown
HY-147202 BRD4 Inhibitor-24 Inhibitor 99.27% Unkown
HY-151594A iBRD4-BD1 diTFA Inhibitor 99.52% Unkown
HY-170380 XY221 Inhibitor / Unkown
HY-111978 ZEN-3862 Inhibitor 98.86% Unkown
HY-160557 PLK1/BRD4-IN-2 Inhibitor 98.92% Unkown
HY-132130 BRD4 Inhibitor-13 Inhibitor 99.08% Unkown
HY-130813 BET-IN-6 Inhibitor / Unkown
HY-146660 BRD4 Inhibitor-18 Inhibitor / Unkown
HY-102044 BET-IN-2 Inhibitor / Unkown
HY-126325 BY27 Inhibitor / Unkown
HY-175224 PROTAC BRD4 Degrader-36 Degrader / Unkown
HY-181759 CBP/p300/BRD4 ligand-1 Ligand / Unkown
HY-170390 AB3067 Degrader / Unkown
HY-172124 PROTAC BRD4 Degrader-29 Degrader / Unkown
HY-175924 BRD3/BRD4-L ligand-2 Ligand / Unkown
HY-183575 JQ1-JX5 Degrader / Unkown
HY-143327 PROTAC BRD4 Degrader-16 Degrader / Unkown
HY-180152 BRD4 ligand 14 Inhibitor / Unkown
HY-50698A (S)-BI 2536 Inhibitor / Unkown
HY-174811 PROTAC BRD4 Degrader-33 Degrader / Unkown
HY-182958 Hsp70TAC BRD4 Degrader-1 Degrader / Unkown
HY-139294 PROTAC BRD4 Degrader-15 Inhibitor / Unkown
HY-147375 Bromodomain inhibitor-10 Inhibitor / Unkown
HY-181869 PROTAC BET Degrader-17 Degrader / Unkown
HY-181442 CK2-TN03 Inhibitor 98.02% Unkown
HY-180957 NEP108 Degrader / Unkown
HY-173062 BRD4 Inhibitor-40 Inhibitor / Unkown
HY-151972 BRD4 Inhibitor-25 Inhibitor / Unkown
HY-136794 SB-284851-BT Inhibitor / Unkown
HY-143299 BRD4-BD1-IN-1 Inhibitor / Unkown
HY-175611 FLT3/JAK2/BRD4 ligand-1 Ligand / Unkown
HY-115541 BRD4-IN-41 Inhibitor / Unkown
HY-131203 PROTAC BRD4 Degrader-6 Degrader / Unkown
HY-162240 SJH1-51B Degrader / Unkown
HY-183339 IL-6/RIPK3-IN-1 Inhibitor / Unkown
HY-182371 BRD4 ligand 15 Ligand / Unkown
HY-163639 BRD4 degrader-2 Inhibitor / Unkown
HY-D3393 JQ1-FITC TFA / Unkown
HY-168634 SJ46421 Inhibitor / Unkown
HY-182577 CFT-743 Degrader / Unkown
HY-174348 BRD4-IN-10 Inhibitor / Unkown
HY-181735 BET-IN-30 Inhibitor / Unkown
HY-180923 AB3145 Degrader / Unkown
HY-175225 PROTAC BRD4 Degrader-37 Degrader / Unkown
HY-181553 PROTAC BRD4 Degrader-44 Degrader / Unkown
HY-160662 BRD4-IN-5 Inhibitor / Unkown
HY-152213 BET-IN-13 Inhibitor / Unkown
HY-183992 CZL-149 Inhibitor / Unkown
HY-144338 PARP1/BRD4-IN-1 Inhibitor / Unkown
HY-183770 LCI40 Inhibitor / Unkown
HY-175033 BRD4-IN-11 Inhibitor / Unkown
HY-180150 PROTAC BRD4 Degrader-42 Degrader / Unkown
HY-150613 PARP1/BRD4-IN-2 Inhibitor / Unkown
HY-176391 Ad-JQ1 Inhibitor / Unkown
HY-174920 PROTAC BRD4 Degrader-34 Inhibitor / Unkown
HY-149806 Bromodomain IN-2 Inhibitor / Unkown
HY-181003 GSK785 Inhibitor / Unkown
HY-181495 RAJQ14 Degrader / Unkown
HY-174975 JY-21 Degrader / Unkown
HY-181496 (S)-JQ-35-Boc Ligand / Unkown
HY-172130 PI3Kδ/BET-IN-1 Inhibitor / Unkown
HY-180909 TMU454 Degrader / Unkown
HY-183061 MrTAC-8 Degrader / Unkown
HY-173564 DW34 Inhibitor / Unkown
HY-179734 PROTAC BRD4 Degrader-41 Degrader / Unkown
HY-161368 BRD-SF2 Degrader / Unkown
HY-173433 JV8 Degrader / Unkown
HY-183077 BRD4 degrader-7 Degrader / Unkown
HY-143328 PROTAC BRD4 Degrader-17 Degrader / Unkown
HY-175242 PROTAC BRD4 ligand-4 Ligand / Unkown
HY-180831 BRD4 D1-IN-3 Inhibitor / Unkown
HY-178984 PI3Kα-IN-28 Inhibitor / Unkown
HY-162876 PROTAC BRD4 ligand-3 Ligand / Unkown
HY-156566 PROTAC BRD4 Degrader-21 Degrader / Unkown
HY-143471 WNY0824 Inhibitor / Unkown
HY-183273 BRD4/AKT-IN-1 Inhibitor / Unkown
HY-142705 BRD4 D1-IN-2 Inhibitor / Unkown
HY-170686 BRD4 Inhibitor-38 Inhibitor / Unkown
HY-180804 CZL-077 Inhibitor / Unkown
HY-182036 KWZL-7f15 Inhibitor / Unkown
HY-178510 JQ1-S(GlcNAc)Cq Degrader / Unkown
HY-143235 BRD4 Inhibitor-15 Inhibitor / Unkown
HY-150941 BRD4 ligand 2 Inhibitor / Unkown
HY-174996 NEP162 Degrader / Unkown
HY-W265951 3-Methylcarbostyril Inhibitor / Unkown
HY-161650 PROTAC BRD4 Degrader-26 Degrader / Unkown
HY-130612 PROTAC BRD2/BRD4 degrader-1 Inhibitor / Unkown
HY-181867 PROTAC BET Degrader-16 Degrader / Unkown
HY-184335 PROTAC BET Degrader-18 Degrader / Unkown
HY-135558 PROTAC BRD4 Degrader-3 Degrader / Unkown
HY-181553A PROTAC BRD4 Degrader-45 Degrader / Unkown
HY-P10445 TAT-PiET Inhibitor / Unkown
HY-169151 PROTAC BRD4-DCAF1 degrader-1 / Unkown
HY-175240 PROTAC BRD4 Degrader-38 Degrader / Unkown
HY-176251 CBP/p300-IN-22 Inhibitor / Unkown
HY-175610 PROTAC FLT3/JAK2/BRD4 Degrader-1 Degrader / Unkown
HY-184339 BRD4-IN-42 Inhibitor / Unkown
HY-104072 BRD4-IN-3 Inhibitor / Unkown
HY-111979 ZEN-3411 Inhibitor / Unkown
HY-149098 SJ1461 Inhibitor / Unkown
HY-158331 Gal-ARV-771 Degrader / Unkown
HY-173327 BRD4 degrader-6 Degrader / Unkown
HY-174210 PROTAC BRD4 Degrader-31 Degrader / Unkown
HY-157460 BRD4 Inhibitor-29 / Unkown
HY-170900 SJ44236 Degrader / Unkown
HY-147374 Bromodomain inhibitor-9 Inhibitor / Unkown
HY-150683 NC-III-49-1 Inhibitor / Unkown
HY-163282 NB512 Inhibitor / Unkown
HY-181854 ZX079 Degrader / Unkown
HY-179589 JQ-1 (carboxylic acid)-amine-PEG8-cyanogen Degrader / Unkown
HY-169170 PARP1/BRD4-IN-3 Inhibitor / Unkown
HY-181758 PROTAC CBP/p300/BRD4 Degrader-1 Degrader / Unkown
HY-143300 BRD4-BD1-IN-2 Inhibitor / Unkown
HY-175767 PROTAC BRD4 Degrader-39 Degrader / Unkown
HY-157290 HL403 Inhibitor / Unkown
HY-132128 BRD4 Inhibitor-12 Inhibitor 99.34% Unkown
HY-184151 KBD-1 Degrader / Unkown
HY-179588 PROTAC BET Degrader-14 Degrader / Unkown
HY-176535 KB-0118 Inhibitor / Unkown
HY-181729 PROTAC BET Degrader-15 Degrader / Unkown
HY-129937 (S)-GNE-987 Inhibitor / Unkown
HY-155680 BET BD2-IN-1 Inhibitor / Unkown
HY-132942 PROTAC BRD4 ligand-2 Ligand 96.69% Unkown
HY-125230 CN427 Inhibitor / Unkown
HY-N16067 Penipanoid C Inhibitor / Unkown
HY-150684 GXH-II-052 Inhibitor / Unkown
HY-182912 PLX-4104 / Unkown
HY-174812 BRD4 ligand 8 Inhibitor / Unkown
HY-181505 BRD4-IN-12 Inhibitor / Unkown
HY-153945 BET-IN-15 Inhibitor / Unkown
HY-182801 PROTAC BRD4 Degrader-46 Degrader / Unkown
HY-181164 PROTAC BRD4 Degrader-43 Degrader / Unkown
HY-177730 PROTAC BRD4 Degrader-40 Degrader / Unkown
HY-153519 WWL0245 Inhibitor / Unkown
HY-136570A GSK778 hydrochloride Inhibitor / Unkown
HY-178094 BRD4 ligand 13 Ligand / Unkown
HY-155222 TW9 Inhibitor / Unkown
HY-181831 XQ2 / Unkown
HY-W173361 CBP/p300-IN-24 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens BRD4 NCBI NCBI:23476