2. Gene
  3. BCHE - butyrylcholinesterase Gene

BCHE - butyrylcholinesterase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 488143 | Gene type: protein coding

About BCHE

Primary_assembly 34: 30,972,845-31,038,271 reverse strand.ROS_Cfam_1.0:CM025133.1

This gene has 1 transcript (splice variant), 130 orthologues and 8 paralogues.

BCHE Products(1)

mRNA Protein Name
NM_001313861.2 NP_001300790.1 cholinesterase precursor

BCHE Protein Structure

COesterase

COesterase: pfam00135 (29 - 549)

AChE_tetra

AChE_tetra: pfam08674 (564 - 598)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 602 a.a.
Protein Preferred Names Protein Names

cholinesterase

acylcholine acylhydrolase

butylcholinesterase

butyrylcholine esterase

choline esterase II

pseudocholinesterase

Related Agents

Approval
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17368 Rivastigmine Inhibitor 99.93% Yes
HY-B1488 Tacrine hydrochloride Inhibitor 99.90% Unkown
HY-107922 Ethopropazine hydrochloride Inhibitor 99.32% Unkown
HY-B1239 Drofenine hydrochloride Inhibitor 98.10% Unkown
HY-B2244 Tacrine hydrochloride hydrate Inhibitor 99.98% Unkown
HY-100919 Ambenonium chloride Inhibitor 96.18% Yes
HY-B1542A Benactyzine hydrochloride Inhibitor 99.02% Unkown
HY-16183 Echothiopate iodide Inhibitor / Unkown
HY-B1239A Drofenine Inhibitor / Unkown
Pre-clinical Phase
Bioactive Molecules (192)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0285 Imperatorin Inhibitor 98.59% Unkown
HY-107569 Garcinol Inhibitor 98.85% Unkown
HY-N0226A Epiberberine chloride Inhibitor 98.91% Unkown
HY-N0631 Cornuside Inhibitor 99.99% Unkown
HY-N4225 Aaptamine Inhibitor 99.71% Unkown
HY-122140 ACG548B Inhibitor 99.72% Unkown
HY-W130025 p-Xylene bispyridinium bromide Inhibitor 99.60% Unkown
HY-N2157 Pteryxin Inhibitor 99.55% Unkown
HY-N2129 N-Nornuciferine Inhibitor 99.94% Unkown
HY-121382 Gypsogenin Inhibitor 99.51% Unkown
HY-119577 Ubretid 99.0% Yes
HY-155140 BChE-IN-17 Inhibitor 99.07% Unkown
HY-N2284 Sophoflavescenol Inhibitor 98.78% Unkown
HY-W130236 Methylene Violet 3RAX Inhibitor 95.54% Unkown
HY-107275 Ebeiedinone Inhibitor 99.51% Unkown
HY-N2960 Broussonin A Inhibitor 97% Unkown
HY-P11392 Ac-IEAR-pNA Substrate 99.82% Unkown
HY-151368 AChE/BChE-IN-10 Inhibitor 99.67% Unkown
HY-103373 PE154 Inhibitor 99.01% Unkown
HY-121072 ASS234 Inhibitor 99.6% Unkown
HY-N0226 Epiberberine Inhibitor 98.46% Unkown
HY-N7263 Galanthamine N-Oxide Inhibitor 99.90% Unkown
HY-N10488 BChE-IN-11 Inhibitor 98.78% Unkown
HY-N12581 Kuwanon U Inhibitor 97.30% Unkown
HY-149212 SD-6 Inhibitor ≥98.0% Unkown
HY-N7346 Lucidadiol Inhibitor 98.0% Unkown
HY-162340 Z32439948 Inhibitor / Unkown
HY-131971 AChE/BChE-IN-1 Inhibitor / Unkown
HY-151436 ZLMT-12 Inhibitor / Unkown
HY-146315 AChE/BChE-IN-6 Inhibitor / Unkown
HY-174328 BChE/AChE-IN-1 Inhibitor / Unkown
HY-168052 hAChE-IN-9 Inhibitor / Unkown
HY-157982 BChE-IN-28 Inhibitor / Unkown
HY-W746884 2-Methyl-2-butenyl (E)-Caffeate Inhibitor / Unkown
HY-181041 Multitarget AD-IN-5 Inhibitor / Unkown
HY-146687 BuChE-IN-4 Inhibitor / Unkown
HY-175211 BChE-IN-42 Inhibitor / Unkown
HY-170389 BChE-IN-39 Inhibitor / Unkown
HY-144446 BuChE-IN-1 Inhibitor / Unkown
HY-146663A AChE/BChE-IN-3 hydrochloride Inhibitor / Unkown
HY-149300 SB-1436 Inhibitor / Unkown
HY-180819 AChE/BChE-IN-33 Inhibitor / Unkown
HY-N18289 8-Hydroxydihydrochelerythrine Inhibitor / Unkown
HY-159143 BChE-IN-33 Inhibitor / Unkown
HY-149090 AChE/BuChE/MAO-B-IN-2 / Unkown
HY-127087 Isogarcinol Inhibitor / Unkown
HY-156031 BChE-IN-19 Inhibitor / Unkown
HY-149273 hBChE-IN-1 Inhibitor / Unkown
HY-162639 α-Glucosidase-IN-68 Inhibitor / Unkown
HY-108048 Desoxypeganine Inhibitor / Unkown
HY-175655 BChE/p38-α MAPK-IN-1 Inhibitor / Unkown
HY-157384 BChE-IN-22 Inhibitor / Unkown
HY-143465 BChE-IN-5 Inhibitor / Unkown
HY-N15710 Magnotriol B Inhibitor / Unkown
HY-157978 AChE-IN-59 Inhibitor / Unkown
HY-163909 AChE-IN-72 Inhibitor / Unkown
HY-159898 AChE/BChE-IN-23 Inhibitor / Unkown
HY-183303 AChE-IN-116 Inhibitor / Unkown
HY-N10781 Isograndifoliol Inhibitor / Unkown
HY-161156 BChE-IN-26 Inhibitor / Unkown
HY-155284 K1833 Inhibitor / Unkown
HY-183760 AChE/BChE-IN-37 Inhibitor / Unkown
HY-175973 AChE/BChE-IN-30 Inhibitor / Unkown
HY-180243 AChE-IN-102 Inhibitor / Unkown
HY-172219 CUR-IPA Inhibitor / Unkown
HY-175524 BChE/MAO-B-IN-2 Inhibitor / Unkown
HY-182615 Cymserine Inhibitor / Unkown
HY-N17425 Lakoochin C Inhibitor / Unkown
HY-180892 Multi-kinase-IN-10 Inhibitor / Unkown
HY-W800535 Cryptolepine Inhibitor / Unkown
HY-181597 LINS05414 Inhibitor / Unkown
HY-180797 S1R agonist/BChE-IN-1 Inhibitor / Unkown
HY-152113 AChE/BChE/MAO-B-IN-3 Inhibitor / Unkown
HY-170938 AChE-IN-82 Inhibitor / Unkown
HY-159880 AChE/BChE-IN-24 Inhibitor / Unkown
HY-146251 BuChE-IN-6 Inhibitor / Unkown
HY-161331 S16–1029 Inhibitor / Unkown
HY-N10701 AChE/BChE-IN-11 Inhibitor / Unkown
HY-182290 AChE/BChE-IN-36 Inhibitor / Unkown
HY-D3171 AD-BChE/HClO / Unkown
HY-161512 hAChE/hBACE-1-IN-4 Inhibitor / Unkown
HY-182254 AChE/BChE-IN-35 Inhibitor / Unkown
HY-168301 CL-13 Inhibitor / Unkown
HY-107272 Chuanbeinone Inhibitor / Unkown
HY-181865 BuChE-IN-22 Inhibitor / Unkown
HY-179126 BChE/MAO-A-IN-1 Inhibitor / Unkown
HY-149288 hAChE/hBACE-1-IN-2 Inhibitor / Unkown
HY-N10489 BChE-IN-12 Inhibitor / Unkown
HY-158261 AChE-IN-63 Inhibitor / Unkown
HY-180891 Multitarget AD-IN-4 Inhibitor / Unkown
HY-172782 BuChE-IN-20 Inhibitor / Unkown
HY-181248 BChE-IN-49 Inhibitor / Unkown
HY-162812 H3R antagonist 4 Inhibitor / Unkown
HY-N9846 Luteolin 5,3'-dimethyl ether / Unkown
HY-161643 S21-1011 Inhibitor / Unkown
HY-172461 MAO-IN-6 Inhibitor / Unkown
HY-179711 AChE/BChE-IN-32 Inhibitor / Unkown
HY-175523 MAO-B-IN-48 Inhibitor / Unkown
HY-173152 AChE/BChE-IN-26 Inhibitor / Unkown
HY-162036 α-Amylase/α-Glucosidase-IN-7 Inhibitor / Unkown
HY-163537 AChE/BuChE-IN-5 Inhibitor / Unkown
HY-158334 NDs-IN-1 Inhibitor / Unkown
HY-170417 hAChE/hBuChE/GSK-3β-IN-1 Inhibitor / Unkown
HY-149243 BChE-IN-16 Inhibitor / Unkown
HY-119292 AP2238 Inhibitor / Unkown
HY-179496 ChE/GSK-3β-IN-1 Inhibitor / Unkown
HY-181851 AChE-IN-109 Inhibitor / Unkown
HY-174464 AChE/BChE-IN-28 Inhibitor / Unkown
HY-150545 AChE-IN-21 Inhibitor / Unkown
HY-180146 BChE-IN-48 Inhibitor / Unkown
HY-169162 hBChE-IN-3 Inhibitor / Unkown
HY-178943 Neuroprotective agent 15 Inhibitor / Unkown
HY-163441 BChE-IN-31 Inhibitor / Unkown
HY-144762 K027 Inhibitor / Unkown
HY-169961 BChE-IN-38 Inhibitor / Unkown
HY-161453 BChE-IN-32 Inhibitor / Unkown
HY-149087 MR2938 Inhibitor / Unkown
HY-178017 BChE/hCA II-IN-1 Inhibitor / Unkown
HY-162671 BuChE-IN-12 Inhibitor / Unkown
HY-180552 AChE-IN-104 Inhibitor / Unkown
HY-149272 tau/Aβ40 aggregation-IN-1 Inhibitor / Unkown
HY-169234 BChE-IN-35 Inhibitor / Unkown
HY-169163 BChE-IN-36 Inhibitor / Unkown
HY-152632 BuChE-IN-7 Inhibitor / Unkown
HY-181167 AChE/BChE-IN-34 Inhibitor / Unkown
HY-153432 TRV-7019 99.64% Unkown
HY-108048A Desoxypeganine hydrochloride Inhibitor / Unkown
HY-155366 hAChE-IN-6 Inhibitor / Unkown
HY-174399 AChE/BChE-IN-27 Inhibitor / Unkown
HY-151405 Z164597606 Inhibitor / Unkown
HY-163746 BuChE-IN-11 Inhibitor / Unkown
HY-158092 ChEs/MAOs-IN-2 Inhibitor / Unkown
HY-179726 BChE-IN-47 Inhibitor / Unkown
HY-114422 ARRY-371797 Inhibitor / Unkown
HY-168731 AChE/BChE-IN-25 Inhibitor / Unkown
HY-157437 AChE/BChE-IN-16 Inhibitor / Unkown
HY-161508 AChE/BChE-IN-19 Inhibitor / Unkown
HY-162681 eeAChE-IN-3 Inhibitor / Unkown
HY-144689 BChE-IN-3 Inhibitor / Unkown
HY-182001 Multi-kinase-IN-13 Inhibitor / Unkown
HY-118729 Difeterol Inhibitor / Unkown
HY-149993 hBChE-IN-2 Inhibitor / Unkown
HY-162693 AChE-IN-68 Inhibitor / Unkown
HY-163514 hAChE-IN-8 Inhibitor / Unkown
HY-149287 hAChE/hBACE-1-IN-1 Inhibitor / Unkown
HY-178433 BChE/p38-α MAPK-IN-2 Inhibitor / Unkown
HY-161150 AChE/BChE-IN-17 Inhibitor / Unkown
HY-179363 BChE-IN-46 Inhibitor / Unkown
HY-152232 BChE-IN-15 Inhibitor / Unkown
HY-180783 AChE/BChE/MAO-A-IN-1 Inhibitor / Unkown
HY-158696 BChE/MAO-B-IN-1 Inhibitor / Unkown
HY-147939 AChE/BuChE-IN-3 Inhibitor / Unkown
HY-158978 Multitarget AD inhibitor-2 Inhibitor / Unkown
HY-161507 hCAI/II-IN-8 Inhibitor / Unkown
HY-157981 AChE-IN-60 Inhibitor / Unkown
HY-179122 BChE-IN-45 Inhibitor / Unkown
HY-N10490 Blestrin D Inhibitor / Unkown
HY-162338 BChE-IN-29 Inhibitor / Unkown
HY-N19871 Monogynol A Inhibitor / Unkown
HY-169962 hCA I-IN-4 Inhibitor / Unkown
HY-163883 BChE-IN-34 Inhibitor / Unkown
HY-175658 AChE/BChE-IN-29 Inhibitor / Unkown
HY-170976 BuChE-IN-16 / Unkown
HY-151562 AChE/BuChE/MAO-B-IN-1 Inhibitor / Unkown
HY-181503 AChE/BuChE-IN-8 Inhibitor / Unkown
HY-183352 BuChE-IN-23 Inhibitor / Unkown
HY-N2129A N-Nornuciferine hydrochloride Inhibitor / Unkown
HY-170561 AChE/BuChE-IN-6 Inhibitor / Unkown
HY-121191 Bisnorcymserine Inhibitor / Unkown
HY-183750 BChE reactivator-1 / Unkown
HY-172460 AChE/BChE/MAO-B-IN-5 Inhibitor / Unkown
HY-152112 AChE/BChE/MAO-B-IN-2 Inhibitor / Unkown
HY-157382 AChE-IN-51 Inhibitor / Unkown
HY-N10486 BChE-IN-10 Inhibitor / Unkown
HY-146669 BChE-IN-6 Inhibitor / Unkown
HY-185347 AChE-IN-114 Inhibitor / Unkown
HY-159482 SBN-284 Inhibitor / Unkown
HY-181445 NSC 620023 TFA Inhibitor / Unkown
HY-161842 AChE-IN-67 Inhibitor / Unkown
HY-149211 AChE/BChE-IN-12 Inhibitor / Unkown
HY-155085 hAChE-IN-3 Inhibitor / Unkown
HY-182786 MAO-B-IN-56 Inhibitor / Unkown
HY-159081 AChE/BChE-IN-20 Inhibitor / Unkown
HY-178356 BChE-IN-44 Inhibitor / Unkown
HY-150585 BuChE-IN-5 Inhibitor / Unkown
HY-B1542 Benactyzine Inhibitor / Unkown
HY-W185336 Dibutyl phenyl phosphate Inhibitor / Unkown
HY-159977 1,2-Didehydrotanshinone IIA Inhibitor / Unkown
HY-W332450 Demeton-S Inhibitor / Unkown
HY-W049312 7-Methoxytacrine Inhibitor / Unkown
HY-N1151 Thunberginol C Inhibitor / Unkown
HY-N19401 Vescalagin Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens BCHE NCBI NCBI:590
Mus musculus BCHE NCBI NCBI:12038