1. Gene
  2. BOC - BOC cell adhesion associated, oncogene regulated Gene

BOC - BOC cell adhesion associated, oncogene regulated Gene

Homo sapiens

Also known as Boi; CDON2

Gene ID: 91653 | Gene type: protein coding

About BOC

Cytogenetic location: 3q13.2 Genomic coordinates (GRCh38): 3:113,210,926-113,287,459 (from NCBI)

This gene has 18 transcripts (splice variants), 197 orthologues and 36 paralogues. Broad expression in skin (RPKM 11.2), prostate (RPKM 10.0) and 23 other tissues.

Summary

The protein encoded by this gene is a member of the immunoglobulin/fibronectin type III repeat family. It is a component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells, and promotes myogenic differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]

BOC Products(19)

mRNA Protein Name
NM_001301861.2 NP_001288790.1 brother of CDO isoform 1 precursor
NM_001301867.2 NP_001288796.1 brother of CDO isoform 3 precursor
NM_001378073.1 NP_001365002.1 brother of CDO isoform 1 precursor
NM_001378074.1 NP_001365003.1 brother of CDO isoform 1 precursor
NM_001378075.1 NP_001365004.1 brother of CDO isoform 2 precursor
NM_001387919.1 NP_001374848.1 brother of CDO isoform 1 precursor
NM_001387920.1 NP_001374849.1 brother of CDO isoform 2 precursor
NM_001387921.1 NP_001374850.1 brother of CDO isoform 2 precursor
NM_001387922.1 NP_001374851.1 brother of CDO isoform 3 precursor
NM_001387923.1 NP_001374852.1 brother of CDO isoform 3 precursor
NM_001387924.1 NP_001374853.1 brother of CDO isoform 4 precursor
NM_001387925.1 NP_001374854.1 brother of CDO isoform 5 precursor
NM_001387926.1 NP_001374855.1 brother of CDO isoform 6 precursor
NM_001387927.1 NP_001374856.1 brother of CDO isoform 7 precursor
NM_001387928.1 NP_001374857.1 brother of CDO isoform 7 precursor
NM_001387929.1 NP_001374858.1 brother of CDO isoform 8 precursor
NM_001387930.1 NP_001374859.1 brother of CDO isoform 8 precursor
NM_001387932.1 NP_001374861.1 brother of CDO isoform 9 precursor
NM_033254.4 NP_150279.1 brother of CDO isoform 2 precursor

BOC Protein Structure

Ig_2

Ig_2: Immunoglobulin domain (36 - 123)

Ig_2

Ig_2: Immunoglobulin domain (133 - 212)

I-set

I-set: Immunoglobulin I-set domain (238 - 311)

I-set

I-set: Immunoglobulin I-set domain (323 - 406)

fn3

fn3: Fibronectin type III domain (485 - 559)

fn3

fn3: Fibronectin type III domain (608 - 693)

fn3

fn3: Fibronectin type III domain (720 - 802)

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  • 1114 a.a.
Protein Preferred Names Protein Names

brother of CDO

Boc homolog

Recombinant BOC Proteins

Cat. No. Product Name Accession Purity
HY-P7671 BOC Protein, Human (HEK293, His) Q96DN7 (A30-S157) ≥95%

Related Diseases

Diseases Alias
Holoprosencephaly

Holoprosencephaly Sequence

Hpe

Hpe - [Holoprosencephaly]

Acrocapitofemoral Dysplasia

ACFD

Dysplasia, Acrocapitofemoral

Chromosome 10q23 Deletion Syndrome
Pallister-Hall Syndrome

PHS

Hypothalamic Hamartomas

Hypothalamic Hamartoblastoma, Hypopituitarism, Imperforate Anus, And Postaxial Polydactyly

Hypothalamic Hamartoblastoma Syndrome

Hamartoma Of The Hypothalamus

Pallister Hall Syndrome

Hall-Pallister Syndrome

Hypothalamic Hamartoblastoma Hypopituitarism Imperforate Anus And Postaxial Polydactyly

Hamartoma, Hypothalamic

Basal Cell Nevus Syndrome

Nevoid Basal Cell Carcinoma Syndrome

Gorlin Syndrome

Nbccs

BCNS

Gorlin-Goltz Syndrome

Multiple Basal Cell Nevi, Odontogenic Keratocysts, And Skeletal Anomalies

Cerebral Gigantism Jaw Cysts

Cramer Niederdellmann Syndrome

Gorlin Syndrome Or Gorlin-Goltz Syndrome

Naevoid Basal Cell Carcinoma Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris BOC VGNC VGNC:38495
Bos taurus BOC VGNC VGNC:26536
Felis catus BOC VGNC VGNC:60145
Mus musculus BOC MGD MGI:2151153
Macaca mulatta BOC VGNC VGNC:70332
Rattus norvegicus BOC RGD RGD:1304550
Others BOC NCBI