TH - tyrosine hydroxylase Gene

Also Known as TYH; DYT14; DYT5b

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 7054

About TH

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:2,163,929-2,171,815 (from NCBI)

This gene has 11 transcripts (splice variants), 188 orthologues, 3 paralogues and is associated with 3 phenotypes. Restricted expression toward adrenal (RPKM 42.8).

Summary

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

TH Products (3)

mRNA	Protein	Name
NM_000360.4	NP_000351.2	tyrosine 3-monooxygenase isoform b
NM_199292.3	NP_954986.2	tyrosine 3-monooxygenase isoform a
NM_199293.3	NP_954987.2	tyrosine 3-monooxygenase isoform c

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables enzyme binding	IPI IPI: Inferred from physical interaction	19703902	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	11943812	GOA
enables tyrosine 3-monooxygenase activity	IDA IDA: Inferred from direct assay	1680128	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in dopamine biosynthetic process	IDA IDA: Inferred from direct assay	12457228	GOA
involved in epinephrine biosynthetic process	IDA IDA: Inferred from direct assay	12457228	GOA
involved in norepinephrine biosynthetic process	IDA IDA: Inferred from direct assay	12457228	GOA
involved in response to ethanol	IDA IDA: Inferred from direct assay	18343820	GOA
involved in response to hypoxia	IDA IDA: Inferred from direct assay	17520326	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	10907721	GOA
located in cytoplasmic side of plasma membrane	IDA IDA: Inferred from direct assay	12457228	GOA
located in cytoplasmic vesicle	IDA IDA: Inferred from direct assay	12457228	GOA
located in melanosome membrane	IDA IDA: Inferred from direct assay	12631248	GOA
located in neuron projection	IDA IDA: Inferred from direct assay	17135716	GOA
located in nucleus	IDA IDA: Inferred from direct assay	21392500	GOA
located in smooth endoplasmic reticulum	IDA IDA: Inferred from direct assay	12457228	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TH Protein Structure

TOH_N

Biopterin_H

0
100
200
300
400
500
528 a.a.

Protein Preferred Names	Protein Names
tyrosine 3-monooxygenase	dystonia 14

Recombinant TH Proteins

Cat. No.	Product Name	Accession	Purity
HY-P73564	Tyrosine Hydroxylase Protein, Human (sf9, His)	P07101-3 (P2-G497)	≥ 90%, as determined by reducing SDS-PAGE.

TH Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80362	Tyrosine Hydroxylase Antibody (YA023)	WB, IHC-P, ICC/IF, FC, IF-Tissue	Human, Mouse, Rat
HY-P83980	Tyrosine Hydroxylase Antibody (YA3677)	WB, IHC-P, FC, ELISA	Human, Rat
HY-P83980A	Tyrosine Hydroxylase Antibody (YA3677)(PBS only)	WB, IHC-P, FC, ELISA	Human, Rat
HY-P85701	Tyrosine Hydroxylase Antibody (YA5393)	WB, ICC/IF, ELISA	Human, Mouse, Rat
HY-P86075	Tyrosine Hydroxylase Antibody (YA5767)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Segawa Syndrome, Autosomal Recessive	Tyrosine Hydroxylase Deficiency Dystonia, Dopa-Responsive, Autosomal Recessive Parkinsonism, Infantile, Autosomal Recessive Segawa Syndrome, Recessive Dyt5b Th-Deficient Drd Tyrosine Hydroxylase-Deficient Dopa-Responsive Dystonia Autosomal Recessive Infantile Parkinsonism Autosomal Recessive Dopa-Responsive Dystonia Autosomal Recessive Dopa Responsive Dystonia Dopa-Responsive Dystonia, Autosomal Recessive Dopa Responsive Dystonia, Autosomal Recessive Dyt/Park-Th Dystonia, Dopa Responsive, Autosomal Recessive Th Deficiency Autosomal Recessive Segawa Syndrome Thy Segawa Syndrome Autosomal Recessive ARSEGS Thd Dystonia, Dopa-Responsive, With Or Without Hyperphenylalaninemia, Autosomal Recessive
Dystonia	Dystonic Disease Dystonic Disorder Dystonia Disorders Neuroleptic Dyskinesia
Dystonia, Dopa-Responsive	Dystonia 5 Dopa-Responsive Dystonia DRD Dyt5 Dystonia-Parkinsonism With Diurnal Fluctuation Dyt-Th Hpd With Diurnal Fluctuation Hereditary Progressive Dystonia With Diurnal Fluctuation Dystonia, Progressive, With Diurnal Variation Segawa Syndrome, Autosomal Dominant Dystonia, Dopa-Responsive, Autosomal Dominant Dopa-Responsive Dystonia, Autosomal Dominant Dystonia, Dopa-Responsive, With Or Without Hyperphenylalaninemia Dyt-Gch1 Dyt-Spr Dystonia 5, Dopa-Responsive Type Hereditary Progressive Dystonia With Marked Diurnal Fluctuation Autosomal Dominant Dopa-Responsive Dystonia Autosomal Dominant Segawa Syndrome Dystonia-5 Progressive Dystonia With Diurnal Fluctuation Dystonia, Type 5, Dopa-Responsive Type
Placental Insufficiency	Uteroplacental Vascular Insufficiency
Hyperphenylalaninemia, Bh4-Deficient, B	Gtp Cyclohydrolase I Deficiency HPABH4B Hyperphenylalaninemia, Tetrahydrobiopterin-Deficient, Due To Gtp Cyclohydrolase I Deficiency Bh4-Deficient Hyperphenylalaninemia B Gtp Cyclohydrolase 1 Deficiency Tetrahydrobiopterin-Deficient Hyperphenylalaninemia B Hyperphenylalaninemia, Tetrahydrobiopterin-Deficient, Due To Gtp Cyclohydrolase 1 Deficiency Gtpch Deficiency Hyperphenylalaninemia Due To Gtp Cyclohydrolase Deficiency Atypical Severe Phenylketonuria Due To Gtp Cyclohydrolase I Deficiency Gch1 Deficiency Guanosine Triphosphate Cyclohydrolase I Deficiency Hyperphenylalaninemia With Neopterin Deficiency
Phenylketonuria	Phenylalanine Hydroxylase Deficiency PKU Pah Deficiency Folling Disease Maternal Phenylketonuria Phenylketonurias Oligophrenia Phenylpyruvica Hyperphenylalaninemia, Non-Pku Mild Folling'S Disease Phenylalaninemia Mild Phenylketonuria Mild Pku Variant Pku Variant Phenylketonuria Mpku Deficiency Disease, Phenylalanine Hydroxylase Phenylketonuria, Maternal Phenylalanine Hydroxylase Deficiency Disease Hyperphenylalaninemic Embryopathy Maternal Pku Maternal Hyperphenylalaninemia Phenylketonuric Embryopathy Hyperphenylalaninemia HPA Non-Phenylketonuria Hyperphenylalaninemia NON-PKU HPA Phenylketonuria Maternal Classical Phenylketonuria Hyperphenylalaninaemia Pku - [Phenylketonuria]
Mood Disorder	Mood Disorders Episodic Mood Disorder
Parkinsonism	Parkinsonism-Plus Idiopathic Parkinsonism Primary Parkinsonism Paralysis Agitans Syndrome Parkinsonian Syndrome Trembling Paralysis Paralysis Agitans Shaking Palsy Shaking Paralysis
Pheochromocytoma	Pheochromocytoma, Susceptibility To Phaeochromocytoma Adrenal Gland Chromaffin Paraganglioma Adrenal Gland Chromaffinoma Adrenal Gland Paraganglioma Adrenal Gland Pheochromocytoma Chromaffin Paraganglioma Of The Adrenal Gland Intraadrenal Paraganglioma PCC Chromaffin Cell Tumor Medullary Chromaffinoma Medullary Paraganglioma Pheochromoblastoma Pheochromocytomas Chromaffin Cell Neoplasm Pheochromocytoma, Malignant
Sudden Infant Death Syndrome	SIDS Sudden Infant Death Syndrome, Susceptibility To Cot Death Crib Death Sudden Death Of Nonspecific Cause In Infancy Sudden Infant Death Death, Sudden, Syndrome, Infant
Multiple System Atrophy 1	Multiple System Atrophy Shy-Drager Syndrome Msa MSA1 Multiple System Atrophy 1, Susceptibility To Sporadic Olivopontocerebellar Atrophy Multisystem Atrophy Msa1, Susceptibility To Multiple System Atrophy, Susceptibility To Opca Progressive Autonomic Failure With Multiple System Atrophy Sds
Dementia, Lewy Body	Lewy Body Dementia Lewy Body Disease Diffuse Lewy Body Disease Dementia With Lewy Bodies DLB Autosomal Dominant Diffuse Lewy Body Disease Cortical Lewy Body Disease Dementia, Lewy Body, Susceptibility To Lewy Body Dementia, Susceptibility To Senile Dementia Of The Lewy Body Type Dementia Of The Lewy Body Type Lbd Diffuse Lewy Body Disease With Gaze Palsy Dysphasic Dementia Hereditary Lewy Body Type Senile Dementia Lewy Body Variant Of Alzheimer Disease Lewy Bodies Lewy Body Dlbd - [Diffuse Lewy Body Disease] Clbd - [Cortical Lewy Body Disease]
Paraganglioma	Chemodectoma Glomus Body Tumor Paragangliomas Carotid Body Paraganglioma Extra-Adrenal Paraganglioma
Stiff-Person Syndrome	SPS Stiff-Man Syndrome Stiff Man Syndrome Stiff Person Syndrome Moersch-Woltman Syndrome Sms Stiff-Trunk Syndrome Morsch Woltman Syndrome Stiff Person Syndrome And Related Disorders Stiff Person Spectrum Disorder Classic Stiff Person Syndrome Classic Sps Focal Stiff Limb Syndrome Focal Stiff-Person Syndrome Stiff Leg Syndrome Progressive Encephalomyelitis With Rigidity
Parkinson Disease, Late-Onset	Parkinson Disease Parkinson'S Disease PD PARK Parkinson Disease, Susceptibility To Late Onset Parkinson'S Disease Late Onset Parkinson Disease Paralysis Agitans Primary Parkinsonism Idiopathic Parkinson Disease Parkinson'S Parkinson Disease, Late-Onset, Susceptibility To Parkinson Disease, Age Of Onset, Modifier Lewy Body Parkinson Disease Idiopathic Parkinson'S Disease Pd - [Parkinson Disease] Parkinson Disease Nos Parkinson, Nos Primary Parkinson Disease
Ganglioglioma	Childhood Ganglioglioma Adult Ganglioglioma Cns Ganglioglioma Mixed Cell Tumors Containing Both Neural Ganglionic Cells And Neural Glial Cell Components
Gilles De La Tourette Syndrome	Tourette Syndrome Tourette Disorder GTS Ts Gilles De La Tourette'S Syndrome Motor-Verbal Tic Disorder Guinon'S Disease Psychogenic Tics Tourette'S Syndrome Chronic Motor And Vocal Tic Disorder Td Tourette'S Disease Combined Vocal And Multiple Motor Tic Disorder [De La Tourette] Combined Vocal And Multiple Motor Tic Disorder Tic De La Tourette
Bipolar Disorder	Bipolar Depression Manic Disorder Depression, Bipolar Bipolar Disorder Manic Phase Depressive-Manic Psych. Manic Bipolar Affective Disorder Manic Bipolar I Disorder Manic Depression Manic Depressive Disorder Mixed Bipolar Disorder Bipolar Affective Disorder Bipolar Affective Psychosis Bipolar Spectrum Disorder Manic Depressive Illness Depression Bipolar Bipolar Disorder, Mixed Major Affective Disorder Major Affective Disorder 1 Major Affective Disorder 2
Wolfram Syndrome	Didmoad Syndrome Didmoad Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness Wfs Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, And Deafness Didmoadud Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Deafness Syndrome Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Hearing Loss Syndrome
Rett Syndrome	Atypical Rett Syndrome RTT Rett Disorder Rts Autism, Dementia, Ataxia, And Loss Of Purposeful Hand Use Rett Syndrome, Preserved Speech Variant Rett Syndrome, Atypical Rett'S Disorder Rett Syndrome Variant Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use Syndrome Cerebroatrophic Hyperammonemia Rett Like Syndrome Rett'S Syndrome Atypical Rtt Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use Rett Syndrome Preserved Speech Variant Rett Syndrome Zappella Variant Rett Syndrome, Zappella Variant
Von Hippel-Lindau Syndrome	Von Hippel-Lindau Disease Vhl Vhl Syndrome VHLS Von Hippel-Lindau Syndrome, Modifier Of Hippel Lindau Syndrome Angiomatosis Retinae Cerebelloretinal Angiomatosis, Familial Hippel-Lindau Disease Familial Cerebelloretinal Angiomatosis Lindau Disease VHLD
Movement Disease	Movement Disorders Movement Disorder
Constipation
Multiple Endocrine Neoplasia	Men Multiple Endocrine Adenomatosis Multiple Endocrine Neoplasia Syndrome Adenomatosis, Familial Endocrine Endocrine Neoplasia, Multiple Familial Endocrine Adenomatosis Mea Multiple Endocrine Neoplasms Multiple Endocrine Neoplasia Type 1
Supranuclear Palsy, Progressive, 1	Progressive Supranuclear Palsy Steele-Richardson-Olszewski Syndrome Supranuclear Palsy, Progressive Progressive Supranuclear Ophthalmoplegia Psp PSNP1 Familial Progressive Supranuclear Palsy Richardson'S Syndrome Psp Syndrome Progressive Supranuclear Palsy 1 Supranuclear Palsy Progressive Ophthalmoplegia, Supranuclear, Progressive Steele-Richardson-Olszewksi Syndrome
Ganglioneuroblastoma
Borderline Personality Disorder
Personality Disorder	Personality Disorders Character Disorder Personality Specific Personality Disorders Enduring Personality Change After Psychiatric Illness
Toxic Encephalopathy	Neurotoxicity Neurotoxicity Syndromes Neurotoxicity Syndrome Encephalopathy, Toxic
Dopamine Beta-Hydroxylase Deficiency	Noradrenaline Deficiency Norepinephrine Deficiency Dopamine Beta Hydroxylase Deficiency Congenital Dopamine Beta-Hydroxylase Deficiency Dopamine Beta-Hydroxylase Deficiency, Congenital Dopamine Β-Hydroxylase Dbh Deficiency
Gastroparesis	Gastroparesis Syndrome Delayed Gastric Emptying Gastric Atonia Gastroparalysis
Central Hypoventilation Syndrome, Congenital, 1	Cchs CCHS1 Central Hypoventilation Syndrome, Congenital, 1, With Or Without Hirschsprung Disease Central Hypoventilation Syndrome, Congenital Congenital Failure Of Autonomic Control Autonomic Control, Congenital Failure Of Ondine Curse, Congenital Ondine Curse Central Hypoventilation Syndrome, Congenital, 1, With Or Without Hirschsprung Hypoventilation, Central, Syndrome, Congenital, Type 1 Congenital Central Hypoventilation Sleep Apnea, Central Central Alveolar Hypoventilation Syndrome Cchs With Hirschsprung Disease Congenital Central Alveolar Hypoventilation Syndrome Sleep-Related Respiratory Failure Hypoventilation
Ganglioneuroma
Amphetamine Abuse
Aromatic L-Amino Acid Decarboxylase Deficiency	Aadc Deficiency Dopa Decarboxylase Deficiency Ddc Deficiency Aromatic Amino Acid Decarboxylase Deficiency Deficiency Of Aromatic-L-Amino-Acid Decarboxylase AADCD Aromatic-L-Amino-Acid Decarboxylase Deficiency Aromatic L-Amino-Acid Decarboxylase Deficiency
Hydrocephalus Due To Congenital Stenosis Of Aqueduct Of Sylvius	Aqueductal Stenosis Aqueductal Stenosis, X-Linked Hsas Hsas1 Hycx Hydrocephalus, X-Linked Xlas X-Linked Hydrocephalus Syndrome
Attention Deficit-Hyperactivity Disorder	Attention Deficit Hyperactivity Disorder ADHD Attention Deficit Disorder Attention Deficit-Hyperactivity Disorder, Susceptibility To Attention Deficit Disorder With Hyperactivity Hyperkinetic Disorder Hyperactivity Of Childhood Attention-Deficit/Hyperactivity Disorder Add Addh Attention Deficit Attention Deficit Disorder Of Childhood With Hyperactivity Attention Deficit Disorder With Hyperactivity Syndrome Hyperkinetic Syndrome Attention-Deficit Hyperactivity Disorder Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type Disturbance Of Activity And Attention Disorder Of Activity And Attention Adhd - [Attention Deficit Hyperactivity Disorder] Hyperkinetic Disorders Disorder Of Activity And Attention With Hyperkinesia Attention Deficit Syndrome With Hyperactivity
Dystonia, Dopa-Responsive, Due To Sepiapterin Reductase Deficiency	Sepiapterin Reductase Deficiency Spr Deficiency Dopa-Responsive Dystonia Due To Sepiapterin Reductase Deficiency Srd Drd Due To Srd Dopa-Responsive Hypersomnia Dyt-Spr Dyt/Park-Spr Sr-Deficient Drd Autosomal Recessive Sepiapterin Reductase-Deficient Drd Spr DRDSPRD Motor And Cognitive Disorder Due To Sepiapterin Reductase Deficiency Psychomotor Disorders
Hyperphenylalaninemia, Bh4-Deficient, A	6-Pyruvoyl-Tetrahydropterin Synthase Deficiency Pts Deficiency HPABH4A Hyperphenylalaninemia, Tetrahydrobiopterin-Deficient, Due To Pts Deficiency Ptsd Bh4-Deficient Hyperphenylalaninemia A Hyperphenylalaninemia Due To 6-Pyruvoyltetrahydropterin Synthase Deficiency Tetrahydobioperin-Deficient Hyperphenylalaninemia Due To Pts Deficiency Hyperphenylalanemia, Bh4-Deficient, A Hyperphenylalaninemia Due To 6-Pyruvoyl-Tetrahydropterin Synthase Deficiency 6-Pyruvoyltetrahydropterin Synthase Deficiency Hyperphenylalaninemia Tetrahydrobiopterin-Deficient Due To Pts Deficiency Ptpsd Hyperphenylalaninemia, Bh4-Deficient, Type A
Adjustment Disorder	Adjustment Reaction Adjustment Disorders Adjustment Disease Brief Situational Non-Psychotic Disorder Adaptation Reaction Nos Emotional Crisis Situational Disorder Situational Disturbance Situational Maladjustment Situational Reaction Situational Reaction With Maladjustment Transient Situational Disturbance
Autoimmune Polyendocrine Syndrome, Type I, With Or Without Reversible Metaphyseal Dysplasia	APS1 Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Apeced Pga I Hypoadrenocorticism With Hypoparathyroidism And Superficial Moniliasis Autoimmune Polyendocrinopathy Syndrome , Type I, With Or Without Reversible Metaphyseal Dysplasia Polyglandular Autoimmune Syndrome, Type 1 Autoimmune Polyglandular Syndrome Type 1 Autoimmune Polyendocrine Syndrome Type 1 Autoimmune Polyendocrinopathy Syndrome Type 1 Whitaker Syndrome Aps Type 1 Polyglandular Type I Autoimmune Syndrome Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Syndrome Aps I Autoimmune Polyglandular Syndrome, Type I Polyglandular Autoimmune Syndrome, Type I Aps 1 Autoimmune Polyglandular Syndrome Type I Pga 1 Pga-I Polyglandular Autoimmune Syndrome Type 1 Type I Polyglandular Autoimmune Syndrome Aire Deficiency Autoimmune Polyendocrinopathy With Candidiasis And Ectodermal Dystrophy Autoimmune Polyglandular Syndrome, Type 1 Autoimmune Polyendocrinopathy Type 1 Apeced Syndrome Autoimmune Hypoparathyroidism-Chronic Candidiasis-Addison Disease Syndrome Ham Syndrome Hypoparathyroidism-Addison Disease-Mucocutaneous Candidiasis Syndrome Medac Syndrome Multiple Endocrine Deficiency-Addison Disease-Candidiasis Syndrome Autoimmune Polyendocrine Syndrome 1, With Or Without Reversible Metaphyseal Dysplasia Aps-1 Autoimmune Polyendocrine Syndrome Type I Autoimmune Polyendocrinopathy Syndrome Type I Autosomal Dominant Autoimmune Polyendocrinopathy Syndrome Type I Polyglandular Autoimmune Syndrome Type I Polyglandular Deficiency Syndrome Persian-Jewish Type Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant Polyendocrinopathy Autoimmune, Type 1, With/Without Reversible Metaphyseal Dysplasia
Hyperphenylalaninemia	Hyperphenylalaninaemia
Schizophrenia	SCZD Schizophrenia With Or Without An Affective Disorder Schizophrenia 12 Schizophrenia, Susceptibility To Schizophrenia-1 Dementia Praecox Schizophrenia 1
Dementia	Dementias Presenile Dementia Alzheimer Type Dementia Alzheimer Sclerosis Alzheimer Disease Dementia Alzheimer Dementia Primary Degenerative Alzheimer Type Dementia End Stage Alzheimer'S Dementia Alzheimer'S Type Atypical Dementia Alzheimer Type Presenile Dementia Early Onset Alzheimer Dementia Dementia In Alzheimer Disease Type 2 Dementia In Alzheimer Disease With Early Onset Early Onset Alzheimer Type Dementia, Uncomplicated Primary Degenerative Alzheimer Type Dementia, Early Onset Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated Alzheimer Disease Dementia With Early Onset Presenile Sclerosis Presenile Brain Sclerosis Presenile Alzheimer Brain Sclerosis Late Onset Alzheimer Dementia Dementia In Alzheimer Disease Type 1 Dementia In Alzheimer Disease With Late Onset Primary Degenerative Alzheimer Type Dementia, Late Onset Sdat - [Senile Dementia, Alzheimer Type] Alzheimer Disease Dementia With Late Onset Late Onset Alzheimer Brain Sclerosis Senile Alzheimer Brain Disease Senile Alzheimer Brain Sclerosis Senile Primary Degenerative Alzheimer Type Dementia Senile Dementia Of The Alzheimer Type Arteriosclerotic Dementia Strategic-Infarct Dementia Post Stroke Dementia Vascular Cognitive Impairment Vascular Dementia Dementia Of The Lewy Body Type Dementia With Lewy Bodies Sdlt - [Senile Dementia Of The Lewy Body Type] Senile Dementia Of The Lewy Body Type Alcohol-Related Dementia Alcoholic Dementia Nos Alcohol-Induced Dementia Alcoholic Brain Syndrome Chronic Alcoholic Brain Syndrome Alcohol Dementia Late Onset Alcoholic Psychosis Residual And Late-Onset Alcohol-Induced Psychotic Disorder Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder Late-Onset Psychoactive Substance-Induced Psychotic Disorder Inhalant Dementia Volatile Solvents Dementia Dementia In Paralysis Agitans Pdd - [Parkinson Disease Dementia] Dementia Syndrome Of Parkinson Disease Dementia In Parkinson Disease Parkinson Related Dementia Dementia In Huntington Chorea Hiv - [Human Immunodeficiency Virus] Dementia Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex Aids Related Dementia Dementia Due To Niacin Deficiency
Rhabdomyosarcoma 2	Alveolar Rhabdomyosarcoma Rhabdomyosarcoma, Alveolar Rhabdomyosarcoma Alveolar RMS2 Rmsa Rhabdomyosarcoma 2, Alveolar Alveolar Childhood Rhabdomyosarcoma Arms Rhabdomyosarcoma, Type 2
Major Depressive Disorder	Seasonal Affective Disorder Unipolar Depression Depression MDD Depressive Disorder Unipolar Depression, Susceptibility To Major Depressive Disorder 1 Major Depressive Disorder, Response To Citalopram Therapy In Major Depressive Disorder 2 Winter Depression Single Major Depressive Episode Sad Clinical Depression Major Depression Depressive Syndrome Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment Seasonal Affective Disorder, Susceptibility To Recurrent Major Depression Affective Disorder, Seasonal Depression In A Seasonal Pattern Depression Seasonal Major Depressive Disorder With A Seasonal Pattern Seasonal Depression Seasonal Mood Disorder Mental Depression Recurrent Major Depressive Episodes
Peripheral Nervous System Benign Neoplasm
Autonomic Nervous System Benign Neoplasm
Alcohol Dependence	Alcoholism Alcohol Dependence, Susceptibility To Alcohol Dependence, Protection Against Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against Alcoholism, Susceptibility To Alcoholic Intoxication, Chronic Pharyngeal Neoplasms Chronic Alcoholism Dipsomania Alcohol Addiction Ethanol Dependence Chronic Ethanolism Chronic Alcoholic Disease Nos Alcoholic Disease Nos Alcoholic
Striatonigral Degeneration
Oculogyric Crisis
Postencephalitic Parkinson Disease	Postencephalitic Parkinsonism Parkinson Disease, Postencephalitic
Neonatal Hypoxic And Ischemic Brain Injury	Perinatal Asphyxia Hypoxic-Ischemic Encephalopathy Perinatal Hypoxia Hie Hypoxic And Ischemic Brain Injury In The Newborn Encephalopathy, Hypoxic Ischemic Encephalopathies Hypoxic-Ischemic Hypoxic Ischemic Encephalopathy Hypoxic Ischaemic Brain Injury Brain Hypoxia Cerebral Hypoxia Hypoxic Encephalopathy Hypoxic Brain Damage Hypoxic Brain Injury Brainstem Hypoxia Hypoxic Brainstem Damage
Psychotic Disorder	Psychotic Disorders Mental Or Behavioural Disorder Psychotic Mental Disorders
Anxiety	Anxiety Disorder Anxiety Disorders Anxiety State Anxieties Anxiety Neurosis
Diabetic Autonomic Neuropathy	Diabetic Neuropathies
Morphine Dependence
Neuroblastoma	Nb Neuroblastoma, Susceptibility To Neuroblastomas Central Neuroblastoma
Beckwith-Wiedemann Syndrome	Wiedemann-Beckwith Syndrome BWS Exomphalos-Macroglossia-Gigantism Syndrome Emg Syndrome Beckwith-Wiedemann Syndrome Due To Cdkn1c Mutation Emg Abnormality Wbs Exomphalos Macroglossia Gigantism Syndrome Beckwith-Wiedemann Syndrome Due To Nsd1 Mutation Macroglossia Exomphalos Gigantism
Impulse Control Disorder	Disruptive, Impulse Control, And Conduct Disorders
Huntington Disease	Huntington'S Disease Huntington Chorea Huntington'S Chorea HD Huntington Chronic Progressive Hereditary Chorea Juvenile Huntington Disease Chronic Progressive Chorea Chronic Progressive Hereditary Chorea Hc - [Huntington Chorea] Hereditary Chorea Progressive Hereditary Chorea
Congenital Central Hypoventilation Syndrome	Cchs Haddad Syndrome Ondine Curse Ondine Syndrome Congenital Central Hypoventilation Congenital Central Alveolar Hypoventilation Syndrome Congenital Failure Of Autonomic Control Ondine'S Curse Primary Alveolar Hypoventilation Ondine-Hirschsprung Disease Central Congenital Hypoventilation Syndrome Congenital Ondine Curse Idiopathic Congenital Central Alveolar Hypoventilation Congenital Central Alveolar Hypoventilation-Hirschsprung Disease Syndrome Ondine-Hirschsprung Syndrome
Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1	Guam Disease Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex Of Guam Als-Pdc Lytico-Bodig Disease Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1, Susceptibility To Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex, Susceptibility To Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Of Guam Syndrome Parkinsonism-Dementia-Als Complex Pdals Amyotrophic Lateral Sclerosis, Parkinsonism/Dementia Complex Of Guam Parkinson-Dementia Complex Of Guam G-Pdc Guam Parkinsonism-Dementia Complex ALS-PDC1 Als/Pdc Of Guam Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic/Parkinsonism/Dementia Complex 1 Amyotrophic Lateral Sclerosis, Guam Form Parkinsonian Disorders
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Developmental And Epileptic Encephalopathy 47	DEE47 Epileptic Encephalopathy, Early Infantile, 47 Eiee47 Developmental And Epileptic Encephalopathy, 47 Early Infantile Epileptic Encephalopathy 47
Sleep Disorder	Sleep Disorders Non-Organic Sleep Disorder
Dissociated Nystagmus
Autonomic Nervous System Disease	Autonomic Nervous System Dysfunction Autonomic Nervous System Disorders Autonomic Nervous System Disorder Autonomic Nervous System Diseases Abnormality Of The Autonomic Nervous System
Hearing Loss, Noise-Induced	Noise-Induced Hearing Loss NIHL Hearing Loss, Noise-Induced, Susceptibility To Hearing Loss Noise-Induced Noise Induced Hearing Loss
Esophageal Atresia	Tracheoesophageal Fistula Congenital Atresia Of Esophagus Congenital Imperforate Esophagus Imperforate Esophagus Oesophageal Atresia Te Fistula Tef Tracheoesophageal Fistula With Or Without Esophageal Atresia
Parkinson Disease 4, Autosomal Dominant	Autosomal Dominant Parkinson Disease 4 PARK4 Parkinson Disease 4, Autosomal Dominant Lewy Body Parkinson Disease 4 Parkinson'S Disease 4 Autosomal Dominant Lewy Body Parkinson Disease 4 Autosomal Dominant Parkinson'S Disease 4 Parkinson Disease 4 Autosomal Dominant Lewy Body Parkinson Disease Autosomal Dominant 4 Parkinson Disease Familial Type 4 Parkinson Disease, Type 4
Autonomic Nervous System Neoplasm	Tumor Of Autonomic Nervous System
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Peripheral Nervous System Neoplasm	Peripheral Nervous System Neoplasms Nerve Sheath Neoplasm Neoplasm Of Peripheral Nerve Tumor Of Pns Nerve Sheath Neoplasms Nerve Sheath Tumors
Amyotrophic Lateral Sclerosis 1	Amyotrophic Lateral Sclerosis ALS Lou Gehrig Disease Amyotrophic Lateral Sclerosis Type 1 Charcot Disease ALS1 Amyotrophic Lateral Sclerosis, Susceptibility To Fals Lou Gehrig'S Disease Mnd Motor Neuron Disease Familial Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis 1, Familial Amyotrophic Lateral Sclerosis 1, Autosomal Dominant Motor Neuron Disease, Bulbar Motor Neurone Disease Amyotrophic Lateral Sclerosis With Dementia Dementia With Amyotrophic Lateral Sclerosis Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic Sclerosis, Lateral, Amyotrophic, Type 1 Amyotrophic Sclerosis Als - [Amyotrophic Lateral Sclerosis] Wasting Palsy Amyotrophic Paralysis Amyotrophy Lateral Sclerosis Wasting Paralysis Spinal Progressive Amyotrophy Progressive Atrophic Paralysis
Disease Of Mental Health	Mental Health Mental Disorders
Choreatic Disease	Chorea Hereditary Chorea
Specific Developmental Disorder
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Stroke, Ischemic	Cerebral Infarction Stroke Ischemic Stroke Cerebrovascular Accident Cerebral Infarction, Susceptibility To Stroke, Ischemic, Susceptibility To Cerebral Infarct Ischemic Stroke, Susceptibility To Stroke, Susceptibility To Cva - Cerebral Infarction ISCHSTR Ischemic Cerebrovascular Accident
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Type 2 Diabetes Diabetes Mellitus, Non-Insulin-Dependent T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Hirschsprung Disease 1	Hirschsprung Disease Aganglionic Megacolon Hscr Hirschsprung'S Disease Congenital Megacolon Congenital Intestinal Aganglionosis Colonic Aganglionosis Hirschsprung Disease, Susceptibility To, 1 Hirschsprung Disease, Protection Against HSCR1 Mgc Pelvirectal Achalasia Total Intestinal Aganglionosis Megacolon, Aganglionic Macrocolon Hscr 1 Hirschsprung Disease Type 1 Hirschsprung Disease, Type 1 Congenital Dilatation Of Colon Aganglionosis Congenital Aganglionic Megacolon Aganglionosis Of Colon Bowel Aganglionosis Colon Aganglionosis Hirschsprung Megacolon
Mitochondrial Complex I Deficiency, Nuclear Type 1	Mitochondrial Complex I Deficiency Nadh:Q(1) Oxidoreductase Deficiency MC1DN1 Nadh-Coenzyme Q Reductase Deficiency Isolated Mitochondrial Respiratory Chain Complex I Deficiency Isolated Nadh-Coenzyme Q Reductase Deficiency Isolated Nadh-Coq Reductase Deficiency Isolated Nadh-Ubiquinone Reductase Deficiency Mitochondrial Nadh Dehydrogenase Component Of Complex I, Deficiency Of Nuclear Type Mitochondrial Complex I Deficiency 1 Isolated Complex I Deficiency Complex 1 Mitochondrial Respiratory Chain Deficiency Nadh Coenzyme Q Reductase Deficiency Complex I Mitochondrial Respiratory Chain Deficiency Deficiency Of Mitochondrial Nadh Dehydrogenase Component Of Complex I Nadh:Ubiquinone Oxidoreductase Deficiency Complex I, Mitochondrial Respiratory Chain, Deficiency Of

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (11)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-117287	Deucravacitinib	Inhibitor	99.93%	Unkown
HY-100754	Ritlecitinib	Inhibitor	99.80%	Yes
HY-N0394	L-Cystine		99.84%	Unkown
HY-107916	Thyrotropin	Inhibitor	/	Unkown
HY-B0976A	Fenoterol hydrobromide	Agonist	99.97%	Unkown
HY-109520	Glatiramer acetate		98.0%	Unkown
HY-B0976	Fenoterol	Agonist	99.08%	Unkown
HY-17002	Suplatast (Tosilate)	Inhibitor	99.67%	Unkown
HY-100754C	Ritlecitinib tosylate	Inhibitor	99.65%	Yes
HY-100754A	Ritlecitinib malonate	Inhibitor	/	Unkown
HY-B0976AR	Fenoterol hydrobromide (Standard)	Agonist	/	Unkown

Inhibitory Antibodies (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99025	Lebrikizumab	Inhibitor	99.90%	Unkown
HY-P99396	Spesolimab	Inhibitor	99.10%	Unkown
HY-P99256	Tildrakizumab	Antagonist	99.46%	Unkown

Clinical Phase

Bioactive Molecules (28)

Cat. No.	Product Name	Effect	Purity	Phase
HY-Y0344D	Sodium chloride, for cell culture	Activator	99.9%	Phase 4
HY-177835	Liposomal Iron		/	Phase 4
HY-124065	ARRY-502	Antagonist	/	Phase 4
HY-150298	Soquelitinib	Inhibitor	99.98%	Phase 3
HY-B2132	Tryptamine		99.89%	Phase 3
HY-112137	Trehalose-6,6'-dibehenate	Activator	99.92%	Phase 3
HY-10535	Evofosfamide	Inducer	98.0%	Phase 3
HY-147410	Ulefnersen		99.22%	Phase 3
HY-13743	Roquinimex	Inhibitor	99.69%	Phase 3
HY-160040	Cobitolimod	Agonist	97.14%	Phase 3
HY-160040A	Cobitolimod sodium	Agonist	/	Phase 3
HY-13743R	Roquinimex (Standard)	Inhibitor	/	Phase 3
HY-155950	TH9619		99.33%	Phase 2
HY-148074	Zelnecirnon	Inhibitor	99.71%	Phase 2
HY-124573	(R)-Odafosfamide		98.52%	Phase 2
HY-15342	Timapiprant	Antagonist	98.12%	Phase 2
HY-132828	Odatroltide	Inhibitor	97.39%	Phase 2
HY-17632	Tarloxotinib bromide	Inhibitor	98.75%	Phase 2
HY-114141	BI-671800	Antagonist	99.36%	Phase 2
HY-118250	GSK2245035		99.79%	Phase 2
HY-149040	Odafosfamide		99.06%	Phase 2
HY-159507	Brezivaptan	Antagonist	96.53%	Phase 2
HY-16734	Amiselimod	Modulator	/	Phase 2
HY-12284	NVP-QAV680	Antagonist	/	Phase 2
HY-103637	Vimirogant	Inhibitor	/	Phase 2
HY-137131	DC-Chol hydrochloride		99.95%	Phase 1
HY-139780	JNJ-61803534	Inhibitor	99.84%	Phase 1
HY-159754	HS201		/	Phase 1

Inhibitory Antibodies (7)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99757	Nivatrotamab	Inhibitor	99.00%	Phase 2
HY-P991266	SM-17	Inhibitor	96.98%	Phase 2
HY-P991510	CDX-1140	Agonist	/	Phase 2
HY-P991633	TQC2938	Inhibitor	/	Phase 2
HY-P991257	MK-1966	Inhibitor	96.17%	Phase 1
HY-P99911	Efizonerimod alfa	Agonist	98.57%	Phase 1
HY-P991258	CNTO-5825		98.18%	Phase 1

Pre-clinical Phase

Bioactive Molecules (256)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-153808	Complete Freund's adjuvant (CFA)		/	Unkown
HY-15826	SGC-CBP30	Inhibitor	99.83%	Unkown
HY-P1240	MOG (35-55) mouse, rat		99.73%	Unkown
HY-126360	Oxazolone		98.0%	Unkown
HY-146244	Agatolimod		98.84%	Unkown
HY-15417	ML-7 hydrochloride		99.88%	Unkown
HY-P10408	Candidalysin	Activator	99.81%	Unkown
HY-150741C	ODN 2216 sodium	Agonist	98.57%	Unkown
HY-125801	3-Oxo-5β-cholanoic acid	Inhibitor	99.62%	Unkown
HY-150741	ODN 2216		98.57%	Unkown
HY-101092	QS-21-Api	Activator	99.73%	Unkown
HY-116961	TH1020		99.81%	Unkown
HY-12776	GSK805	Inhibitor	99.83%	Unkown
HY-147313	TH10785	Activator	99.93%	Unkown
HY-P1240A	MOG (35-55) TFA		99.68%	Unkown
HY-113238A	Lithocholic acid 3-sulfate disodium		99.93%	Unkown
HY-138113	Pyrrothiogatain	Inhibitor	98.61%	Unkown
HY-143712	Allolithocholic acid		99.69%	Unkown
HY-W009203	L-Cystine dihydrochloride		98.0%	Unkown
HY-106224B	Orexin A (human, rat, mouse) acetate	Agonist	99.53%	Unkown
HY-153808B	Complete Freund's adjuvant (CFA, 1 mg/ml)		/	Unkown
HY-114360	Taurohyodeoxycholic acid	Inhibitor	99.73%	Unkown
HY-134771	YM-341619	Inhibitor	98.01%	Unkown
HY-107413	SR11237		99.99%	Unkown
HY-101392	Harmane	Inhibitor	99.91%	Unkown
HY-P2797A	Chitinase, Streptomyces griseus		/	Unkown
HY-N2279	Kurarinone	Activator	99.47%	Unkown
HY-P1181A	Pam2CSK4 TFA		99.46%	Unkown
HY-N4084	Thonningianin A	Inducer	99.73%	Unkown
HY-123604	TH1834		99.79%	Unkown
HY-12814	TH588	Inhibitor	99.20%	Unkown
HY-N0440	Germacrone		99.76%	Unkown
HY-P3993A	(Gly14)-Humanin (human) acetate	Inhibitor	99.86%	Unkown
HY-N6636	Valencene	Inhibitor	81.81%	Unkown
HY-111818	TH34	Inhibitor	99.52%	Unkown
HY-161296	TH6342	Inhibitor	99.15%	Unkown
HY-W012732	Isoquinoline	Inhibitor	99.58%	Unkown
HY-W017982	CMIT/MIT (14.5% in water)		97.0%	Unkown
HY-123604A	TH1834 dihydrochloride		99.89%	Unkown
HY-136065	bpV(phen)		98.0%	Unkown
HY-W011220	Ciglitazone	Agonist	99.74%	Unkown
HY-125390	SM-360320	Agonist	99.41%	Unkown
HY-N0885	Telocinobufagin		99.93%	Unkown
HY-16734A	Amiselimod hydrochloride	Agonist	98.86%	Yes
HY-16965	TH287	Inhibitor	98.99%	Unkown
HY-119684	Maresin 2	Inhibitor	97.20%	Unkown
HY-122630	TH-257	Inhibitor	98.36%	Unkown
HY-W009356	L-Cystine hydrochloride		98.0%	Unkown
HY-125209	TH5427	Inhibitor	99.92%	Unkown
HY-N0723	Neomangiferin		99.80%	Unkown
HY-150167	TH-Z93	Inhibitor	98.41%	Unkown
HY-122818	BpV(phen) trihydrate		98.0%	Unkown
HY-150217	CpG ODN 10101	Agonist	99.44%	Unkown
HY-P2797	Chitinase, Serratia marcescens		/	Unkown
HY-W016174	Diphenyl sulfide		99.71%	Unkown
HY-108522	PA452	Antagonist	≥99.0%	Unkown
HY-150168	TH-Z145	Inhibitor	99.69%	Unkown
HY-N4087	Platycodin D2	Inducer	99.84%	Unkown
HY-N6066	Praeruptorin E		99.83%	Unkown
HY-B0927	Hydrastine	Inhibitor	99.57%	Unkown
HY-126328	PKC-theta inhibitor 1	Inhibitor	99.45%	Unkown
HY-N0594	Deacetylasperulosidic Acid		99.44%	Unkown
HY-W010520	Methylisothiazolinone		99.43%	Unkown
HY-Y0344J	Sodium chloride, for molecular biology		99.97%	Unkown
HY-145848	ERRγ agonist-1	Agonist	98.02%	Unkown
HY-159102	PVP-037.2	Agonist	99.18%	Unkown
HY-147410A	Ulefnersen sodium		98.47%	Unkown
HY-135909	TH1217	Modulator	99.20%	Unkown
HY-W677684	Nurr1 agonist 2	Agonist	98.03%	Unkown
HY-Y0344I	Sodium chloride, meets analytical specification of Ph. Eur. BP USP, ≤0.00002% Al		99.99%	Unkown
HY-114495	Caerulomycin A	Inhibitor	98.0%	Unkown
HY-N3138	Ombuoside		99.68%	Unkown
HY-P10532	Myelin basic protein, MBP (68-86)		99.86%	Unkown
HY-156466	QL-1200186	Inhibitor	99.95%	Unkown
HY-146243	TH-Z835		99.58%	Unkown
HY-164278	diABZI-V/C-Mal		99.28%	Unkown
HY-N10534	Lewis X trisaccharide	Inhibitor	99.91%	Unkown
HY-N7501	Isoformononetin	Inhibitor	99.47%	Unkown
HY-P10109	G6PI 325-339 (human)	Activator	95.00%	Unkown
HY-W018829	10-Undecenal		98.36%	Unkown
HY-120000	MS402	Inhibitor	98.36%	Unkown
HY-151539	TH470	Inhibitor	99.62%	Unkown
HY-173025	Nurr1 agonist 12	Agonist	99.62%	Unkown
HY-15342A	Timapiprant sodium	Inhibitor	99.61%	Unkown
HY-126037	(±)-ML 209	Antagonist	98.14%	Unkown
HY-153663	TH-Z827	Inhibitor	95.12%	Unkown
HY-N3388	Licoisoflavone B	Inhibitor	99.46%	Unkown
HY-N7512	Asimilobine		99.9%	Unkown
HY-P3993	(Gly14)-Humanin (human)	Inhibitor	95.39%	Unkown
HY-101092B	QS-21-Xyl		97.23%	Unkown
HY-101392A	Harmane hydrochloride	Inhibitor	99.96%	Unkown
HY-123468	HA-1004	Inhibitor	99.04%	Unkown
HY-138115	7ß,27-Dihydroxycholesterol	Activator	99.58%	Unkown
HY-145809	FASN-IN-5	Inhibitor	99.98%	Unkown
HY-179537	Selovoxolone	Inhibitor	98.97%	Unkown
HY-P1252	Parathyroid Hormone (1-34), bovine	Agonist	99.88%	Unkown
HY-W010243S	Methylisothiazolinone-d3 hydrochloride		99.42%	Unkown
HY-134113	Z-Gly-Pro-Arg-pNA		98.47%	Unkown
HY-16668	Tyrphostin A1	Inhibitor	98.96%	Unkown
HY-W783276	18:1(11-cis) PC		≥99.0%	Unkown
HY-103637A	Vimirogant hydrochloride	Inhibitor	98.39%	Unkown
HY-110295	SPL-334	Inhibitor	99.6%	Unkown
HY-120574	TH1338	Inhibitor	98.77%	Unkown
HY-120785	SR1555	Antagonist	99.69%	Unkown
HY-142998	Vaxfectin		99.94%	Unkown
HY-158694A	TLR7 agonist 20 hydrochloride	Agonist	99.86%	Unkown
HY-P2299A	Protein E7(43-62) TFA		98.85%	Unkown
HY-113238F	FITC-Lithocholic acid 3-sulfate		90.01%	Unkown
HY-167692	JI069	Inhibitor	98.03%	Unkown
HY-N0394S5	L-Cystine-13C6,15N2		98.4%	Unkown
HY-164485	INI-4001		/	Unkown
HY-135843	TH-263	Control	99.0%	Unkown
HY-142938	RORγt agonist 3	Agonist	98.12%	Unkown
HY-144002	RIBI-529		/	Unkown
HY-145491	Resolvin D5	Inhibitor	98.3%	Unkown
HY-153662	TH-Z816	Inhibitor	98.92%	Unkown
HY-155219	TH9028		/	Unkown
HY-174903	ITK-IN-6	Inhibitor	99.02%	Unkown
HY-N10116A	Calamenene		/	Unkown
HY-N9447	Norbergenin	Inhibitor	98.31%	Unkown
HY-P10463A	ssK36 TFA	Inhibitor	99.34%	Unkown
HY-P1052A	Myelin Basic Protein(87-99) TFA		99.23%	Unkown
HY-P5333A	Aβ1-14-εK-KKK-MvF5 Th acetate	Inhibitor	99.93%	Unkown
HY-W010243	Methylisothiazolinone hydrochloride		99.93%	Unkown
HY-W017982A	CMIT/MIT (2.0-2.5% in water)		/	Unkown
HY-W777360	Harman-13C2,15N	Inhibitor	99.66%	Unkown
HY-127023	Eicosapentaenoyl serotonin	Inhibitor	99.0%	Unkown
HY-138143	N-(p-Tosyl)-GPR-pNA acetate		99.9%	Unkown
HY-B0976AS	Fenoterol-d6 hydrobromide	Agonist	98.02%	Unkown
HY-P5333	Aβ1-14-εK-KKK-MvF5 Th		98.05%	Unkown
HY-117287A	Deucravacitinib (hydrochloride)	Inhibitor	/	Unkown
HY-128353	ROR agonist-1	Antagonist	/	Unkown
HY-125444	TH251	Inhibitor	/	Unkown
HY-126252	A-9758	Inhibitor	/	Unkown
HY-130243	RORγt Inverse agonist 6	Antagonist	98.97%	Unkown
HY-142806	RORγt inverse agonist 26		/	Unkown
HY-101871	Trehalose 6-behenate		/	Unkown
HY-107413G	SR11237 (GMP)		/	Unkown
HY-112348	HA-1004 hydrochloride	Inhibitor	/	Unkown
HY-116890	CRTh2 antagonist 4	Antagonist	/	Unkown
HY-118250A	GSK2245035 maleate		/	Unkown
HY-118428	Fluenetil		/	Unkown
HY-120225	NJK14047	Inhibitor	/	Unkown
HY-120785A	SR1555 hydrochloride	Antagonist	/	Unkown
HY-122349	Lotrifen		/	Unkown
HY-123568	PBI-1393	Inhibitor	/	Unkown
HY-125209A	TH5427 hydrochloride		/	Unkown
HY-125693	L685818	Inhibitor	/	Unkown
HY-125801S	3-Oxo-5β-cholanoic acid-d4		/	Unkown
HY-132851	Corixetan		/	Unkown
HY-134192	TH301		/	Unkown
HY-135773	CRTh2 antagonist 3		/	Unkown
HY-137292	PTB7-Th		/	Unkown
HY-139193	TH1760	Inhibitor	/	Unkown
HY-142703	RORγt inverse agonist 28	Inhibitor	/	Unkown
HY-142937	RORγt agonist 2	Agonist	/	Unkown
HY-143712R	Allolithocholic acid (Standard)		/	Unkown
HY-143712S1	Allolithocholic Acid-d4		/	Unkown
HY-143885	JAK1/TYK2-IN-3	Inhibitor	/	Unkown
HY-145577	Lafadofensine	Inhibitor	/	Unkown
HY-149029	TH-6		96.64%	Unkown
HY-155505	AHR agonist 4	Agonist	/	Unkown
HY-155680	BET BD2-IN-1	Inhibitor	/	Unkown
HY-157020	UniPR1449	Antagonist	/	Unkown
HY-158694	TLR7 agonist 20	Agonist	/	Unkown
HY-161255	3,4-DAA	Inhibitor	/	Unkown
HY-162490	TF-S14	Inhibitor	/	Unkown
HY-162727	GCS-12		/	Unkown
HY-163704	KRN7000 analog 1		/	Unkown
HY-163801	Nurr1 agonist 9	Agonist	/	Unkown
HY-168207	TH023	Inhibitor	/	Unkown
HY-168347	TH152	Ligand	/	Unkown
HY-172692	DSPE-PEG1000-TH		/	Unkown
HY-172693	DSPE-PEG2000-TH		/	Unkown
HY-172694	DSPE-PEG5000-TH		/	Unkown
HY-175365	GCS-12–6	Ligand	/	Unkown
HY-175876	ADAM17-IN-1	Inhibitor	/	Unkown
HY-176262	TH10184	Ligand	/	Unkown
HY-176263	TH10184-octanedioic acid		/	Unkown
HY-176273	RORγt inverse agonist 35	Agonist	/	Unkown
HY-176535	KB-0118	Inhibitor	/	Unkown
HY-177277	HM5023507	Inhibitor	/	Unkown
HY-178240	rel-(1S,2R)-Dihydro bupropion	Inhibitor	/	Unkown
HY-178721	Lithocholic amide-C2-N(didecane)	Inhibitor	/	Unkown
HY-178966	STING agonist-48	Agonist	/	Unkown
HY-181739	GCB-27a	Activator	/	Unkown
HY-181740	GCB-27b	Activator	/	Unkown
HY-184214	Antileishmanial agent-44		/	Unkown
HY-184273	TH-407a	Inhibitor	/	Unkown
HY-186084	ACSL5-IN-4		/	Unkown
HY-187480A	DOPE-PEG2000-TH		/	Unkown
HY-187773A	DPPE-PEG2000-TH		/	Unkown
HY-189091	Iso-Kaempferol		/	Unkown
HY-D3366	Th-TMR-S-Halo		/	Unkown
HY-D3367	Th-TMR-S-SNAP		/	Unkown
HY-N15846	VSA 1		/	Unkown
HY-N16465	Cinnamtannin D1	Inhibitor	/	Unkown
HY-N18080	Parthenin	Inhibitor	/	Unkown
HY-N18279	Bulbocapnine	Antagonist	/	Unkown
HY-N20748	Lansiumamide B	Inhibitor	/	Unkown
HY-N6636R	Valencene (Standard)	Inhibitor	/	Unkown
HY-N7501S	Isoformononetin-d3		98.64%	Unkown
HY-N7869	Celangulin VII		/	Unkown
HY-P10109A	G6PI 325-339 (human) hydrochloride	Activator	/	Unkown
HY-P10982	SjDX5-53	Inducer	/	Unkown
HY-P1181	Pam2CSK4		/	Unkown
HY-P11838	DOTA-TH10		/	Unkown
HY-P1252A	Parathyroid Hormone (1-34), bovine TFA	Agonist	/	Unkown
HY-P2299	Protein E7(43-62)		/	Unkown
HY-P2797B	Chitinase		/	Unkown
HY-P2797C	Chitinase,Trichoderma viride		/	Unkown
HY-P4389	(Asp28)-Glucagon (1-29) (human, rat, porcine)	Activator	/	Unkown
HY-P4790	Acetyl-Exenatide	Inhibitor	/	Unkown
HY-RS14467	TH Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W010520R	Methylisothiazolinone (Standard)		/	Unkown
HY-W012732S2	Isoquinoline-15N		/	Unkown
HY-W016174S	Diphenyl sulfide-d1		99.5%	Unkown
HY-W683409	Dimorpholamine		/	Unkown
HY-W700834	Harman-d3		/	Unkown
HY-W761985	Furathiocarb		/	Unkown
HY-W772717	L-Cystine disodium monohydrate		/	Unkown
HY-W795993	TJU103	Inhibitor	/	Unkown
HY-Y0344H	Sodium chloride, United States Pharmacopeia (USP) Reference Standard		/	Unkown
HY-107413R	SR11237 (Standard)		/	Unkown
HY-11054	TH-237A		98.08%	Unkown
HY-112863	RORγt inhibitor 3	Inhibitor	/	Unkown
HY-119038	ML-7		/	Unkown
HY-119684S	Maresin 2	Inhibitor	/	Unkown
HY-123468A	HA-1004 dihydrochloride	Inhibitor	/	Unkown
HY-12814A	TH588 hydrochloride	Inhibitor	/	Unkown
HY-148014	TH7299		/	Unkown
HY-157675	1,2-Dinervonoyl-sn-glycero-3-phosphocholine		/	Unkown
HY-164454	AJI-100	Inhibitor	/	Unkown
HY-164455	AJI-214	Inhibitor	/	Unkown
HY-16965A	TH287 hydrochloride	Inhibitor	/	Unkown
HY-174603	Human IL4R mRNA		/	Unkown
HY-174607	Human IL33 mRNA		/	Unkown
HY-174639	Human IL13 mRNA		/	Unkown
HY-174641	Human IL12B mRNA		/	Unkown
HY-174642	Human IL12A mRNA		/	Unkown
HY-175301	TH16		/	Unkown
HY-175376	QPyN16Th	Inhibitor	/	Unkown
HY-177300	TLR7/8 agonist 13		/	Unkown
HY-183046	PAICS-IN-1	Activator	/	Unkown
HY-183448	ETMTC		/	Unkown
HY-188018	Mouse Tnf ASO	Inhibitor	/	Unkown
HY-N0594R	Deacetylasperulosidic Acid (Standard)		/	Unkown
HY-N0976	1,11b-Dihydro-11b-hydroxymedicarpin	Activator	/	Unkown
HY-N3548	Catalpalactone	Inhibitor	/	Unkown
HY-P10463	ssK36	Inhibitor	/	Unkown
HY-RS16660	Th Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23095	Th Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W018829R	10-Undecenal (Standard)		/	Unkown
HY-W130878	4-Octylphenol	Activator	/	Unkown
HY-W745349	rel-(1S,2R)-Dihydro bupropion-d9 hydrochloride	Inhibitor	/	Unkown
HY-W777138	rel-(1S,2R)-Dihydro bupropion-d9	Inhibitor	/	Unkown

Inhibitory Antibodies (15)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990121	Anti-Mouse IL-4 Antibody (11B11)	Inhibitor	97.67%	Unkown
HY-P99301	Lokivetmab	Inhibitor	99.34%	Unkown
HY-P990219	Anti-Mouse IL-2 Antibody (JES6-1A12)	Inhibitor	99%	Unkown
HY-P990145	Anti-Mouse VISTA Antibody (13F3)	Inhibitor	≥95.0%	Unkown
HY-P991761	Anti-Mouse CXCL10 Antibody (1F11)	Inhibitor	97.564%	Unkown
HY-P990208	Anti-Mouse IL-9 Antibody (9C1)	Inhibitor	95.00%	Unkown
HY-P990124	Anti-Mouse GITR Antibody (DTA-1)		98.47%	Unkown
HY-P990796	Anti-Mouse IL-2 Antibody (S4B6-1)	Inhibitor	96.97%	Unkown
HY-P992132	Solaprubart	Inhibitor	99.59%	Unkown
HY-P990177	Anti-Mouse Notch4 Antibody (HMN4-14)	Inhibitor	/	Unkown
HY-P990206	Anti-Mouse Jagged 2 Antibody (HMJ2-1)	Inhibitor	/	Unkown
HY-P991274	BMS-986010	Inhibitor	/	Unkown
HY-P991380	TXB4	Inhibitor	/	Unkown
HY-P991467	RG-7258	Inhibitor	/	Unkown
HY-P990252	Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2)		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TH	VGNC	VGNC:66147
Rattus norvegicus	TH	RGD	RGD:3853
Bos taurus	TH	VGNC	VGNC:35816
Canis familiaris	TH	VGNC	VGNC:47322
Mus musculus	TH	MGD	MGI:98735
Macaca mulatta	TH	VGNC	VGNC:78342
Others	TH	NCBI