SRC - SRC proto-oncogene, non-receptor tyrosine kinase Gene

Also Known as ASV; SRC1; THC6; c-SRC; p60-Src

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 6714

About SRC

Cytogenetic location: 20q11.23 Genomic coordinates (GRCh38): 20:37,344,699-37,406,050 (from NCBI)

This gene has 14 transcripts (splice variants), 261 orthologues, 32 paralogues and is associated with 74 phenotypes. Ubiquitous expression in stomach (RPKM 19.0), testis (RPKM 19.0) and 25 other tissues.

Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon Cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

SRC Products (21)

mRNA	Protein	Name
NM_198291.3	NP_938033.1	proto-oncogene tyrosine-protein kinase Src
NM_005417.5	NP_005408.1	proto-oncogene tyrosine-protein kinase Src
XM_047440397.1	XP_047296353.1	proto-oncogene tyrosine-protein kinase Src isoform X1
XM_047440407.1	XP_047296363.1	proto-oncogene tyrosine-protein kinase Src isoform X3
XM_047440398.1	XP_047296354.1	proto-oncogene tyrosine-protein kinase Src isoform X1
XM_047440400.1	XP_047296356.1	proto-oncogene tyrosine-protein kinase Src isoform X1
XM_047440396.1	XP_047296352.1	proto-oncogene tyrosine-protein kinase Src isoform X1
XM_047440403.1	XP_047296359.1	proto-oncogene tyrosine-protein kinase Src isoform X2
XM_047440406.1	XP_047296362.1	proto-oncogene tyrosine-protein kinase Src isoform X2
XM_047440405.1	XP_047296361.1	proto-oncogene tyrosine-protein kinase Src isoform X2
XM_047440408.1	XP_047296364.1	proto-oncogene tyrosine-protein kinase Src isoform X3
XM_047440413.1	XP_047296369.1	proto-oncogene tyrosine-protein kinase Src isoform X2
XM_047440404.1	XP_047296360.1	proto-oncogene tyrosine-protein kinase Src isoform X2
XM_017028026.2	XP_016883515.1	proto-oncogene tyrosine-protein kinase Src isoform X1
XM_047440401.1	XP_047296357.1	proto-oncogene tyrosine-protein kinase Src isoform X2
XM_047440410.1	XP_047296366.1	proto-oncogene tyrosine-protein kinase Src isoform X2
XM_047440399.1	XP_047296355.1	proto-oncogene tyrosine-protein kinase Src isoform X1
XM_047440402.1	XP_047296358.1	proto-oncogene tyrosine-protein kinase Src isoform X2
XM_047440411.1	XP_047296367.1	proto-oncogene tyrosine-protein kinase Src isoform X2
XM_047440409.1	XP_047296365.1	proto-oncogene tyrosine-protein kinase Src isoform X3
XM_047440412.1	XP_047296368.1	proto-oncogene tyrosine-protein kinase Src isoform X2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables BMP receptor binding	IPI IPI: Inferred from physical interaction	26598555	GOA
enables SH2 domain binding	IPI IPI: Inferred from physical interaction	8070403	GOA
enables enzyme binding	IPI IPI: Inferred from physical interaction	21724833	GOA
enables ephrin receptor binding	IPI IPI: Inferred from physical interaction	12925710	GOA
enables heme binding	IDA IDA: Inferred from direct assay	21036157	GOA
enables integrin binding	IPI IPI: Inferred from physical interaction	19141530	GOA
enables non-membrane spanning protein tyrosine kinase activity	IDA IDA: Inferred from direct assay	11606584	GOA
enables phospholipase activator activity	IDA IDA: Inferred from direct assay	11606584	GOA
enables phospholipase binding	IPI IPI: Inferred from physical interaction	11606584	GOA
enables phosphoprotein binding	IPI IPI: Inferred from physical interaction	16441665	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	7478590	GOA
enables protein kinase activity	IDA IDA: Inferred from direct assay	18616680	GOA
enables protein tyrosine kinase activity	EXP EXP: Inferred from Experiment	1381360	GOA
enables protein tyrosine kinase activity	IDA IDA: Inferred from direct assay	16441665	GOA
enables protein tyrosine kinase activity	IMP IMP: Inferred from mutant phenotype	20624904	GOA
enables scaffold protein binding	IPI IPI: Inferred from physical interaction	25006397	GOA
enables signaling receptor binding	IPI IPI: Inferred from physical interaction	19332538	GOA
enables transmembrane transporter binding	IPI IPI: Inferred from physical interaction	8953041	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in cellular response to reactive oxygen species	IMP IMP: Inferred from mutant phenotype	25501895	GOA
involved in focal adhesion assembly	IMP IMP: Inferred from mutant phenotype	21411625	GOA
involved in integrin-mediated signaling pathway	IMP IMP: Inferred from mutant phenotype	24036928	GOA
involved in interleukin-6-mediated signaling pathway	IDA IDA: Inferred from direct assay	25731159	GOA
involved in intestinal epithelial cell development	IDA IDA: Inferred from direct assay	25731159	GOA
involved in intracellular signal transduction	IDA IDA: Inferred from direct assay	11606584	GOA
involved in negative regulation of anoikis	IMP IMP: Inferred from mutant phenotype	22402981	GOA
involved in negative regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	19767770	GOA
involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	IMP IMP: Inferred from mutant phenotype	19767770	GOA
involved in negative regulation of extrinsic apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	19767770	GOA
involved in negative regulation of hippo signaling	IMP IMP: Inferred from mutant phenotype	33162394	GOA
involved in negative regulation of intrinsic apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	19767770	GOA
involved in negative regulation of mitochondrial depolarization	IMP IMP: Inferred from mutant phenotype	19767770	GOA
involved in negative regulation of protein-containing complex assembly	IMP IMP: Inferred from mutant phenotype	19767770	GOA
acts upstream of negative regulation of telomere maintenance	IMP IMP: Inferred from mutant phenotype	21531765	GOA
involved in negative regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	21531765	GOA
acts upstream of or within peptidyl-tyrosine phosphorylation	IDA IDA: Inferred from direct assay	22732588	GOA
involved in peptidyl-tyrosine phosphorylation	IMP IMP: Inferred from mutant phenotype	11606584	GOA
involved in positive regulation of Notch signaling pathway	IDA IDA: Inferred from direct assay	25731159	GOA
involved in positive regulation of TORC1 signaling	IDA IDA: Inferred from direct assay	35927303	GOA
involved in positive regulation of dephosphorylation	IDA IDA: Inferred from direct assay	23159740	GOA
involved in positive regulation of epithelial cell migration	IMP IMP: Inferred from mutant phenotype	18054784	GOA
involved in positive regulation of lamellipodium morphogenesis	IMP IMP: Inferred from mutant phenotype	18054784	GOA
involved in positive regulation of peptidyl-tyrosine phosphorylation	IMP IMP: Inferred from mutant phenotype	26598555	GOA
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP IMP: Inferred from mutant phenotype	19767770	GOA
involved in positive regulation of protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	19059439	GOA
involved in positive regulation of small GTPase mediated signal transduction	IMP IMP: Inferred from mutant phenotype	18541665	GOA
involved in protein autophosphorylation	IDA IDA: Inferred from direct assay	16441665	GOA
involved in regulation of caveolin-mediated endocytosis	IMP IMP: Inferred from mutant phenotype	21724833	GOA
involved in regulation of cell-cell adhesion	IMP IMP: Inferred from mutant phenotype	21724833	GOA
involved in regulation of early endosome to late endosome transport	IMP IMP: Inferred from mutant phenotype	21724833	GOA
involved in regulation of epithelial cell migration	IMP IMP: Inferred from mutant phenotype	21724833	GOA
involved in regulation of toll-like receptor 3 signaling pathway	IDA IDA: Inferred from direct assay	37158982	GOA
involved in response to interleukin-1	IMP IMP: Inferred from mutant phenotype	19281832	GOA
involved in stress fiber assembly	IMP IMP: Inferred from mutant phenotype	24036928	GOA
involved in transforming growth factor beta receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	24036928	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in caveola	IDA IDA: Inferred from direct assay	17848177	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	16441665	GOA
located in cytosol	IDA IDA: Inferred from direct assay	19767770	GOA
located in late endosome	IDA IDA: Inferred from direct assay	20605918	GOA
located in lysosome	IDA IDA: Inferred from direct assay	20605918	GOA
located in mitochondrial inner membrane	IDA IDA: Inferred from direct assay	12615910	GOA
located in mitochondrion	IDA IDA: Inferred from direct assay	19767770	GOA
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	19307596	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	20605918	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SRC Protein Structure

SH3_1

SH2

Pkinase_Tyr

0
100
200
300
400
500
536 a.a.

Protein Preferred Names	Protein Names
proto-oncogene tyrosine-protein kinase Src	proto-oncogene c-Src protooncogene SRC, Rous sarcoma tyrosine kinase pp60c-src tyrosine-protein kinase SRC-1 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

SRC Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	SRC	P12931	KDR	Homo sapiens	P35968	Anti Bait CoIP	18662404
Intra	SRC	P12931	CDCP1	Homo sapiens	Q9H5V8	Anti Bait CoIP	15851033
Intra	SRC	P12931	CDCP1	Homo sapiens	Q9H5V8	Pull Down	15851033
Intra	SRC	P12931	CDCP1	Homo sapiens	Q9H5V8	Anti Tag CoIP	31980649
Intra	SRC	P12931	MET	Homo sapiens	P08581	FPS	24728074
Intra	SRC	P12931	MET	Homo sapiens	P08581	Anti Bait CoIP	35405500
Intra	SRC	P12931	PAK2	Homo sapiens	Q13177	Phage Display	16374509
Intra	SRC	P12931	PAK2	Homo sapiens	Q13177	Filter Binding	16374509
Intra	SRC	P12931	SPRR2A	Homo sapiens	P35326	Anti Tag CoIP	18155796
Intra	SRC	P12931	SPRR2A	Homo sapiens	P35326	Protein Array	18155796
Intra	SRC	P12931	SPRR2A	Homo sapiens	P35326	Anti Bait CoIP	18155796
Intra	SRC	P12931	TNS3	Homo sapiens	Q68CZ2	Anti Bait CoIP	19732724
Intra	SRC	P12931	GRB10	Homo sapiens	Q13322-4	Validated Y2H	32814053
Intra	SRC	P12931	GRB10	Homo sapiens	Q13322-4	Y2H Pooling	32814053
Intra	SRC	P12931	GRB10	Homo sapiens	Q13322-4	Y2H Array	32814053
Intra	SRC	P12931	KHDRBS1	Homo sapiens	Q07666	Pull Down	7537265
Intra	SRC	P12931	KHDRBS1	Homo sapiens	Q07666	Y2H Pooling	16169070
Intra	SRC	P12931	KIT	Homo sapiens	P10721	FPS	24728074
Intra	SRC	P12931	SRCIN1	Homo sapiens	Q9C0H9	Anti Bait CoIP	17525734
Intra	SRC	P12931	PTPRA	Homo sapiens	P18433	Anti Bait CoIP	11923305
Intra	SRC	P12931	PTPRA	Homo sapiens	P18433	CoIP	10698938
Intra	SRC	P12931	PTPRA	Homo sapiens	P18433	Pull Down	11923305
Intra	SRC	P12931	KLF15	Homo sapiens	Q9UIH9	Validated Y2H	32814053
Intra	SRC	P12931	KLF15	Homo sapiens	Q9UIH9	Y2H Pooling	32814053
Intra	SRC	P12931	KLF15	Homo sapiens	Q9UIH9	Y2H Array	32814053
Intra	SRC	P12931	PTPN21	Homo sapiens	Q16825	Anti Bait CoIP	15143158
Intra	SRC	P12931	CDC37	Homo sapiens	Q16543	Anti Bait CoIP	31980649
Intra	SRC	P12931	CDC37	Homo sapiens	Q16543	Anti Tag CoIP	31980649
Intra	SRC	P12931	CDC37	Homo sapiens	Q16543	Pull Down	32707033
Intra	SRC	P12931	HSP90AA1	Homo sapiens	P07900	Pull Down	32707033
Intra	SRC	P12931	HSP90AA1	Homo sapiens	P07900	Anti Tag CoIP	31980649
Intra	SRC	P12931	EGFR	Homo sapiens	P00533	Anti Bait CoIP	21278788
Intra	SRC	P12931	EGFR	Homo sapiens	P00533	Ub Reconstruction	24658140
Intra	SRC	P12931	EGFR	Homo sapiens	P00533	Anti Bait CoIP	20935677
Intra	SRC	P12931	EGFR	Homo sapiens	P00533	Anti Bait CoIP	17284441
Intra	SRC	P12931	PTK2B	Homo sapiens	Q14289	Pull Down	8849729
Intra	SRC	P12931	HNRNPK	Homo sapiens	P61978	BiFC	17178840
Intra	SRC	P12931	HNRNPK	Homo sapiens	P61978	Pull Down	17178840
Intra	SRC	P12931	HNRNPK	Homo sapiens	P61978	Anti Tag CoIP	17178840
Intra	SRC	P12931	CSNK2A1	Homo sapiens	P68400	Anti Tag CoIP	31980649
Intra	SRC	P12931	CSNK2A1	Homo sapiens	P68400	Anti Bait CoIP	21075308
Intra	SRC	P12931	ACTN1	Homo sapiens	P12814	Anti Bait CoIP	16291744
Intra	SRC	P12931	RPL10	Homo sapiens	P27635	Anti Bait CoIP	16741966
Intra	SRC	P12931	RPL10	Homo sapiens	P27635	Pull Down	16741966
Intra	SRC	P12931	RPL10	Homo sapiens	P27635	Anti Tag CoIP	16741966
Intra	SRC	P12931	AFDN	Homo sapiens	P55196	Imaging	17491594
Intra	SRC	P12931	AFDN	Homo sapiens	P55196	Filter Binding	17491594
Intra	SRC	P12931	ESR1	Homo sapiens	P03372-4	Anti Tag CoIP	20935677
Intra	SRC	P12931	ADRB2	Homo sapiens	P07550	Pull Down	17170700
Intra	SRC	P12931	GAB1	Homo sapiens	Q13480	FPS	24728074
Intra	SRC	P12931	CBL	Homo sapiens	P22681	ITC	18273061
Intra	SRC	P12931	CBL	Homo sapiens	P22681	Anti Bait CoIP	17094785
Intra	SRC	P12931	CBL	Homo sapiens	P22681	Protein Kinase Assay	17141222
Intra	SRC	P12931	CBL	Homo sapiens	P22681	Anti Tag CoIP	17094785
Intra	SRC	P12931	LPIN1	Homo sapiens	Q14693	Y2H Pooling	32814053
Intra	SRC	P12931	LPIN1	Homo sapiens	Q14693	Validated Y2H	32814053
Intra	SRC	P12931	LPIN1	Homo sapiens	Q14693	Y2H Array	32814053
Intra	SRC	P12931	AR	Homo sapiens	P10275	FPS	24728074
Intra	SRC	P12931	ROR1	Homo sapiens	Q01973	Protein Kinase Assay	22439932
Cross	SRC	P12931	Arap3	Mus musculus	Q8R5G7	Anti Bait CoIP	15546919
Cross	SRC	P12931	Arap3	Mus musculus	Q8R5G7	Anti Tag CoIP	15546919
Intra	SRC	P12931	ERBB2	Homo sapiens	P04626	Anti Bait CoIP	21075308
Intra	SRC	P12931	ERBB2	Homo sapiens	P04626	Anti Bait CoIP	19372587
Intra	SRC	P12931	PTK2	Homo sapiens	Q05397	Anti Bait CoIP	22402981
Intra	SRC	P12931	PTK2	Homo sapiens	Q05397	CoIP	21034468
Intra	SRC	P12931	HK1	Homo sapiens	P19367	Anti Bait CoIP	28054552
Intra	SRC	P12931	HK1	Homo sapiens	P19367	Crosslink	28054552
Intra	SRC	P12931	ARRB2	Homo sapiens	P32121	Anti Bait CoIP	19122674
Intra	SRC	P12931	PECAM1	Homo sapiens	P16284	Pull Down	9162084
Intra	SRC	P12931	PECAM1	Homo sapiens	P16284	Protein Kinase Assay	10801826
Intra	SRC	P12931	RAB11B	Homo sapiens	Q15907	Y2H Pooling	32814053
Intra	SRC	P12931	RAB11B	Homo sapiens	Q15907	Validated Y2H	32814053
Intra	SRC	P12931	RAB11B	Homo sapiens	Q15907	Y2H Array	32814053
Intra	SRC	P12931	FBH1	Homo sapiens	Q8NFZ0	Anti Tag CoIP	23954233
Intra	SRC	P12931	SDCBP	Homo sapiens	O00560	Anti Bait CoIP	18832467
Intra	SRC	P12931	CDH1	Homo sapiens	P12830	Anti Bait CoIP	21685945
Intra	SRC	P12931	LNX1	Homo sapiens	Q8TBB1	Anti Tag CoIP	17936276
Intra	SRC	P12931	LNX1	Homo sapiens	Q8TBB1	IF	17936276
Intra	SRC	P12931	ZNF232	Homo sapiens	Q9UNY5	Validated Y2H	32814053
Intra	SRC	P12931	ZNF232	Homo sapiens	Q9UNY5	Y2H Pooling	32814053
Intra	SRC	P12931	ZNF232	Homo sapiens	Q9UNY5	Y2H Array	32814053
Cross	SRC	P12931	Ptk2	Mus musculus	P34152	Anti Bait CoIP	18464795
Intra	SRC	P12931	ADAM15	Homo sapiens	Q13444	Filter Binding	16374509
Intra	SRC	P12931	ADAM15	Homo sapiens	Q13444	Phage Display	16374509
Intra	SRC	P12931	ESR1	Homo sapiens	P03372	PLA	23065768
Intra	SRC	P12931	ESR1	Homo sapiens	P03372	Anti Bait CoIP	17284441
Intra	SRC	P12931	ESR1	Homo sapiens	P03372	Anti Bait CoIP	24498420
Intra	SRC	P12931	ESR1	Homo sapiens	P03372	Anti Bait CoIP	23065768
Intra	SRC	P12931	ESR1	Homo sapiens	P03372	Pull Down	14963108
Intra	SRC	P12931	LYN	Homo sapiens	P07948	Pull Down	32707033
Intra	SRC	P12931	LYN	Homo sapiens	P07948	Anti Bait CoIP	18070987
Intra	SRC	P12931	LYN	Homo sapiens	P07948	Anti Bait CoIP	22581261
Intra	SRC	P12931	PIK3R1	Homo sapiens	P27986	PLA	23397142
Intra	SRC	P12931	PIK3R1	Homo sapiens	P27986	Anti Bait CoIP	23065768
Intra	SRC	P12931	PIK3R1	Homo sapiens	P27986	Anti Bait CoIP	24498420
Intra	SRC	P12931	PIK3R1	Homo sapiens	P27986	Anti Bait CoIP	19903481
Intra	SRC	P12931	PIK3R3	Homo sapiens	Q92569	Validated Y2H	25814554
Intra	SRC	P12931	PIK3R3	Homo sapiens	Q92569	Anti Bait CoIP	22402981
Intra	SRC	P12931	IKBKG	Homo sapiens	Q9Y6K9	Anti Bait CoIP	15749833
Intra	SRC	P12931	IKBKG	Homo sapiens	Q9Y6K9	Anti Tag CoIP	15749833
Intra	SRC	P12931	ETS1	Homo sapiens	P14921-1	Protein Kinase Assay	25117710
Intra	SRC	P12931	BECN1	Homo sapiens	Q14457	Y2H Array	32814053
Intra	SRC	P12931	BECN1	Homo sapiens	Q14457	Y2H Pooling	32814053
Intra	SRC	P12931	BECN1	Homo sapiens	Q14457	Validated Y2H	32814053
Intra	SRC	P12931	PTPN1	Homo sapiens	P18031	Phosphatase Assay	11007774
Intra	SRC	P12931	PTPN1	Homo sapiens	P18031	Phosphatase Assay	17974954
Intra	SRC	P12931	PTPN1	Homo sapiens	P18031	CoIP	12857726
Intra	SRC	P12931	PTPN1	Homo sapiens	P18031	Anti Bait CoIP	16115959
Intra	SRC	P12931	PTPN1	Homo sapiens	P18031	Phosphatase Assay	16537444
Intra	SRC	P12931	RAPGEF1	Homo sapiens	Q13905	Peptide Array	17474147
Cross	SRC	P12931	Ptprj	Rattus norvegicus	Q62884	CoIP	15735685
Cross	SRC	P12931	Ptprj	Rattus norvegicus	Q62884	Pull Down	15735685
Cross	SRC	P12931	Ptprj	Rattus norvegicus	Q62884	Biochemical	15735685

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant SRC Proteins

Cat. No.	Product Name	Accession	Purity
HY-P73422	Src Protein, Human (Active, sf9, His-GST)	P12931 (M1-L536)	≥ 90%, as determined by reducing SDS-PAGE.

SRC Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80338	Src Antibody (YA061)	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
HY-P80514	Phospho-Src (Tyr419) Antibody (YA150)	WB, FC	Human
HY-P82911	Phospho-Src (Tyr530) Antibody (YA2656)	WB, IP	Rat
HY-P82911A	Phospho-Src (Tyr530) Antibody (YA2656)(PBS only)	WB, IP	Rat
HY-P86105	Phospho-Src Family(Tyr416) Antibody (YA5797)	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
HY-P86318	Src Antibody (YA6010)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Stroke, Ischemic	Cerebral Infarction Stroke Ischemic Stroke Cerebrovascular Accident Cerebral Infarction, Susceptibility To Stroke, Ischemic, Susceptibility To Cerebral Infarct Ischemic Stroke, Susceptibility To Stroke, Susceptibility To Cva - Cerebral Infarction ISCHSTR Ischemic Cerebrovascular Accident
Acute Promyelocytic Leukemia	Leukemia, Acute Promyelocytic Acute Myeloblastic Leukemia Type 3 Aml M3 APL Leukemia, Acute Promyelocytic, Somatic Aml With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Apml Acute Myeloblastic Leukemia 3 Acute Myeloid Leukemia With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Acute Myeloblastic Leukaemia Type 3 Acute Myeloid Leukaemia M3 Acute Myeloid Leukemia M3 Acute Promyelocytic Leukaemia M3 Anll Myeloid Leukemia, Acute, M3 Leukemia Promyelocytic Acute Leukemia, Promyelocytic, Acute Leukemia, Acute, Promyelocytic
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Protection Against Lung Cancer, Susceptibility To Adenocarcinoma Of Lung, Somatic Nonsmall Cell Lung Cancer Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Cherubism	CRBM Familial Benign Giant-Cell Tumor Of The Jaw Familial Fibrous Dysplasia Of Jaw Familial Multilocular Cystic Disease Of The Jaws
Pertussis	Whooping Cough Bordetella Infections Bordetella Infection Bordetella Pertussis Infection Wc - Whooping Cough Whooping Cough Due To Unspecified Organism Bordetellosis Tussis Convulsiva Whooping Cough, Unspecified Organism Wc - [Whooping Cough] Whooping Cough Due To B. Parapertussis Infection Due To Bordetella Parapertussis
Thrombocytopenia 6	THC6 Thrombocytopenia, Autosomal Dominant, 6 Hereditary Thrombocytopenia With Early-Onset Myelofibrosis
Teeth Hard Tissue Disease
Adenocarcinoma	Adenocarcinomas Adenoacanthoma Of Unspecified Site Adenocarcinoid Of Unspecified Site Adenocarcinoid Tumour Of Unspecified Site Adenocarcinoma And Carcinoid Combined Of Unspecified Site Adenocarcinoma Nos
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Cryptogenic Fibrosing Alveolitis Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Medulloblastoma	MDB Cpnet Localized Primitive Neuroectodermal Tumor Classic Medulloblastoma Desmoplastic/Nodular Medulloblastoma Medulloblastoma With Extensive Nodularity Desmoplastic Medulloblastoma Medulloblastoma, Somatic Medulloblastoma, Desmoplastic Brain Medulloblastoma Cns Pnet Infratentorial Primitive Neuroectodermal Tumor Mben Medulloblastoma Desmoplastic Neuroectodermal Tumors, Primitive Medulloblastomas Medulloblastoma, With Extensive Nodularity Medulloblastoma Of Unspecified Site Medullomyoblastoma Of Unspecified Site
Amyotrophic Lateral Sclerosis 1	Amyotrophic Lateral Sclerosis ALS Lou Gehrig Disease Amyotrophic Lateral Sclerosis Type 1 Charcot Disease ALS1 Amyotrophic Lateral Sclerosis, Susceptibility To Fals Lou Gehrig'S Disease Mnd Motor Neuron Disease Familial Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis 1, Familial Amyotrophic Lateral Sclerosis 1, Autosomal Dominant Motor Neuron Disease, Bulbar Motor Neurone Disease Amyotrophic Lateral Sclerosis With Dementia Dementia With Amyotrophic Lateral Sclerosis Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic Sclerosis, Lateral, Amyotrophic, Type 1 Amyotrophic Sclerosis Als - [Amyotrophic Lateral Sclerosis] Wasting Palsy Amyotrophic Paralysis Amyotrophy Lateral Sclerosis Wasting Paralysis Spinal Progressive Amyotrophy Progressive Atrophic Paralysis
Hepatitis B	Chronic Hepatitis B Hepatitis B Infection Serum Hepatitis HBV Hepatitis B Chronic Hbv, Susceptibility To Hepatitis B, Chronic Chronic Hepatitis B Without Delta Agent Chronic Hbv - [Hepatitis B Virus] Infection Hepatitis B Nos Chronic Type B Viral Hepatitis Hep B Nos
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Bladder Cancer	Urinary Bladder Cancer Bladder Carcinoma Urinary Bladder Carcinoma Bladder Neoplasm Bladder Tumor Cancer, Bladder Malignant Neoplasm Of Urinary Bladder Carcinoma Of Bladder Bladder Cancer, Somatic Tumor Of The Bladder Carcinoma Of Urinary Bladder Bladder Carcinoma Urinary Cancer Of The Urinary Bladder Cancer, Urinary Bladder Malignant Bladder Neoplasm Malignant Bladder Tumor Neoplasm Of The Bladder Neoplasm Of The Urinary Bladder Tumor Of The Urinary Bladder Urinary Bladder Neoplasm BLC Urothelial Carcinoma Of The Bladder Bladder Tumors Urinary Bladder Neoplasms Bladder Cancer Nos Vesical Cancer Nos Malignant Neoplasm Of Bladder, Part Unspecified Malignant Tumour Of Urinary Bladder Primary Malignant Neoplasm Of Bladder
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Cancer Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Noonan Syndrome 1	Noonan Syndrome NS1 Male Turner Syndrome Female Pseudo-Turner Syndrome Turner Phenotype With Normal Karyotype Noonan Syndrome With Pigmented Villonodular Synovitis Turner'S Phenotype, Karyotype Normal Familial Turner Syndrome Noonan'S Syndrome Noonan-Ehmke Syndrome Ns Pseudo-Ullrich-Turner Syndrome Turner Syndrome In Female With X Chromosome Turner-Like Syndrome Ullrich-Noonan Syndrome Noonan-Like/Multiple Giant Cell Lesion Syndrome Noonan Syndrome-Like Disorder With Multiple Giant Cell Lesions Pterygium Colli Syndrome Noonan Syndrome, Type 1 Turner Syndrome, Male
Colon Adenocarcinoma	Adenocarcinoma Of Colon Adenocarcinoma Of The Colon Colonic Adenocarcinoma
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy
Otopalatodigital Syndrome Spectrum Disorder	Opd Spectrum Disorder Opsd Fronto-Otopalatodigital Osteodysplasia
Bone Disease	Bone Diseases Skeletal Disease Skeletal Disorder Disorder Of Skeletal System
Malignant Pleural Mesothelioma	Malignant Mesothelioma Of Pleura Pleural Malignant Mesothelioma
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Rasopathy	Ras/Mitogen-Activated Protein Kinase Syndrome
Lung Squamous Cell Carcinoma	Squamous Cell Carcinoma Of Lung Squamous Cell Lung Carcinoma Epidermoid Cell Carcinoma Of The Lung Squamous Cell Lung Cancer
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Diabetes Mellitus, Non-Insulin-Dependent Type 2 Diabetes T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes
Breast Adenocarcinoma	Mammary Adenocarcinoma Adenocarcinoma Of Breast
Gastrointestinal Stromal Tumor	GIST Gastrointestinal Stromal Tumors Gastrointestinal Stromal Sarcoma Gastrointestinal Stromal Tumor, Familial Gant Gastrointestinal Stromal Tumour Stromal Tumor Of Gastrointestinal Tract Stromal Tumour Of Gastrointestinal Tract Gastrointestinal Stromal Neoplasm Paraganglioma And Gastric Stromal Sarcoma Plexosarcoma
Myocardial Infarction	Heart Attack Myocardial Infarction, Susceptibility To Myocardial Infarction 1 Myocardial Infarction, Protection Against Myocardial Infarction, Decreased Susceptibility To Myocardial Infarction, Decreased Myocardial Infarct MCI1 Premature Myocardial Infarction Myocardial Infarction, Susceptibility To, Type 1
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Juvenile Myelomonocytic Leukemia	Leukemia, Juvenile Myelomonocytic JMML Leukemia, Juvenile Myelomonocytic, Somatic Juvenile Chronic Myelomonocytic Leukemia Juvenile Chronic Myelogenous Leukemia Leukemia, Myelomonocytic, Juvenile Juvenile Myelomonocytic Leukaemia Without Mention Of Remission
Fragile X Syndrome	FXS Martin-Bell Syndrome Fraxa Syndrome Marker X Syndrome X-Linked Mental Retardation And Macroorchidism Fragile X Mental Retardation Syndrome Fra Syndrome Mental Retardation, X-Linked, Associated With Marxq28 Frax Syndrome Symptomatic Form Of Fragile X Syndrome In Female Carriers Fragile-X Syndrome Fraxe Syndrome
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Pylorus Cancer	Ca Pylorus - Stomach Malignant Neoplasm Of Prepylorus Malignant Neoplasm Of Pylorus Of Stomach Malignant Tumor Of Pylorus Malignant Neoplasm Of Pylorus
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Pancreatic Cancer	Pancreatic Carcinoma Familial Pancreatic Carcinoma Pancreatic Neoplasm Carcinoma Of Pancreas Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Cancer Of The Pancreas Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Glioblastoma	Glioblastoma Multiforme Gbm Adult Glioblastoma Multiforme Grade Iv Adult Astrocytic Tumor Primary Glioblastoma Multiforme Spongioblastoma Multiforme Adult Glioblastoma Primary Glioblastoma
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1
Squamous Cell Carcinoma, Head And Neck	Squamous Cell Carcinoma Of The Head And Neck HNSCC Head And Neck Squamous Cell Carcinoma Head And Neck Cancer Squamous Cell Carcinoma Of Lip Squamous Cell Carcinoma, Head And Neck, Somatic Carcinoma Of The Head And Neck Squamous Cell Carcinomas Of Head And Neck Scchn Squamous Cell Carcinoma Of The Hypopharynx Squamous Cell Carcinoma Of The Oropharynx Squamous Cell Carcinoma Of Salivary Glands Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses Squamous Cell Carcinoma Of The Oral Cavity Squamous Cell Carcinoma Of The Lip Carcinoma, Squamous Cell Of Head And Neck Lip Squamous Cell Carcinoma Cancer, Head/Neck Carcinoma, Squamous Cell, Head And Neck Salivary Gland Squamous Cell Carcinoma Cancer Of Head And Neck Squamous Cell Carcinoma Of Oropharynx Nos
Leukemia, Chronic Myeloid	Chronic Myeloid Leukemia Chronic Myelogenous Leukemia CML Chronic Granulocytic Leukemia Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib Chronic Myeloid Leukaemia Chronic Granulocytic Leukaemia Chronic Myelogenous Leukaemia Myeloid Leukemia, Chronic Leukemia, Chronic Myelogenous Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic Cml - Chronic Myelogenous Leukemia Cgl Chronic Myelocytic Leukemia Leukemia, Chronic Myeloid, Atypical ACML Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative Myeloid Leukemia Chronic Leukemia, Myeloid, Chronic Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative Cml- [Chronic Myeloid Leukaemia] Cgl - [Chronic Granulocytic Leukaemia] Chronic Myelocytic Leukaemia
Melanoma, Uveal	Uveal Melanoma Choroidal Melanoma Melanoma Of Uvea Iris Melanoma Malignant Melanoma Of Choroid Malignant Melanoma Of Iris
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Myeloid And Lymphoid Neoplasms Associated With Fgfr1 Abnormalities
Pulmonary Disease, Chronic Obstructive	Chronic Obstructive Pulmonary Disease COPD Pulmonary Disease, Chronic Obstructive, Severe Early-Onset Chronic Obstructive Lung Disease Chronic Obstructive Airway Disease Pulmonary Disease, Chronic Obstructive, Susceptibility To Cold Severe Early-Onset Chronic Obstructive Pulmonary Disease Pulmonary Disease Chronic Obstructive Pulmonary Disease, Obstructive, Chronic, Susceptibility To Chronic Obstructive Pulmonary Disease Of Horses Common Cold Upper Respiratory Infections Copd - [Chronic Obstructive Pulmonary Disease] Coad - [Chronic Obstructive Airways Disease] Cold - [Chronic Obstructive Lung Disease] Chronic Airway Disease Nos Chronic Airways Limitation, Unspecified Chronic Obstructed Airway, Unspecified Chronic Obstructive Airway Disease, Unspecified Chronic Obstructive Airway, Unspecified Obstructive Lung Disease Nos Chronic Obstructive Lung Disease Nos Chronic Obstructive Lung Nos Obstructive Pulmonary Disease Nos Exacerbation Copd Nos Acute Exacerbation Copd
Skin Disease	Skin Diseases Abnormality Of The Skin Skin Diseases, Genetic Genodermatosis Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
Autosomal Dominant Polycystic Kidney Disease	Polycystic Kidney Disease, Adult Type Adpkd Polycystic Kidney Diseases Polycystic Kidney, Autosomal Dominant Congenital Biliary Ectasias Polycystic Kidney And Hepatic Disease 1 Polycystic Kidney Disease, Autosomal Dominant Kidney, Polycystic, Disease, Autosomal Dominant Adult Polycystic Kidney Disease Polycystic Kidney, Adult Type Apckd - [Autosomal Polycystic Kidney Disease]
Neuroblastoma	Nb Neuroblastoma, Susceptibility To Neuroblastomas Central Neuroblastoma
Signet Ring Cell Adenocarcinoma	Signet Ring Cell Carcinoma Carcinoma, Signet Ring Cell Signet Ring Carcinoma Carcinoma Signet Ring Cell
Metachondromatosis	METCDS MC
Agammaglobulinemia	Hypogammaglobulinemia Ighm Mu Heavy Chain Deficiency Mu-Heavy Chain Disease Mu-Hcd Mu-Chain Disease
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Congenital Anomaly Of Heart Heart Defect Heart Malformation Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Estrogen-Receptor Positive Breast Cancer
Myelofibrosis	Primary Myelofibrosis Agnogenic Myeloid Metaplasia Idiopathic Myelofibrosis Myeloid Metaplasia Myelofibrosis With Myeloid Metaplasia Osteomyelofibrosis Megakaryocytic Myelosclerosis Myelosclerosis Chronic Idiopathic Myelofibrosis Myelofibrosis, Idiopathic Myelofibrosis With Myeloid Metaplasia, Somatic Myelofibrosis, Somatic Aleukemic Myelosis Bone Marrow Fibrosis MYELOF MMM Agnogenic Myeloid Metaplasia With Myelofibrosis Ammm Myelosclerosis With Myeloid Metaplasia Myelofibrosis Nos
Agammaglobulinemia, X-Linked	X-Linked Agammaglobulinemia XLA Bruton Type Agammaglobulinemia Bruton'S Agammaglobulinemia Bruton-Type Agammaglobulinemia Agmx1 Imd1 Agammaglobulinemia, X-Linked 1 Btk-Deficiency Agammaglobulinemia Hypogammaglobulinemia Agammaglobulinemia, X-Linked, Type 1 Immunodeficiency 1 Bruton Agammaglobulinemia Tyrosine Kinase Deficiency Bruton'S Agammaglobulinaemia Bruton'S Sex-Linked Agammaglobulinemia Bruton'S Type Agammaglobulinemia Btk Deficiency Agammaglobulinemia, Btk Agammaglobulinemia, Bruton Tyrosine Kinase Congenital Agammaglobulinemia Immunodeficiency Type 1 X-Linked Agammaglobulinemia Type 1
Pancreatic Adenocarcinoma	Adenocarcinoma Of Pancreas Adenocarcinoma Of The Pancreas Pancreas Adenocarcinoma Malignant Exocrine Neoplasm Primary Pancreatic Adenocarcinoma Adenocarcinoma Of Islet Cell Of Pancreas Islet Cell Adenocarcinoma Of Unspecified Site Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site
Frank-Ter Haar Syndrome	Ter Haar Syndrome Borrone Dermatocardioskeletal Syndrome FTHS Autosomal Recessive Melnick-Needles Syndrome Borrone Di Rocco Crovato Syndrome Megalocornea, Multiple Skeletal Anomalies, And Developmental Delay Melnick-Needles Syndrome, Autosomal Recessive, Formerly Frank Ter Haar Syndrome
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Breast Carcinoma In Situ	Carcinoma In Situ Of Breast Non-Infiltrating Carcinoma Of Breast Breast Cancer In Situ
Lung Cancer Susceptibility 3	Lung Adenocarcinoma Adenocarcinoma Of Lung LNCR3 Adenocarcinoma Of Lung, Susceptibility To Bronchogenic Lung Adenocarcinoma Nonsmall Cell Adenocarcinoma Adenocarcinoma Lung Lung Adenocarcinomas Non-Small Cell Adenocarcinoma
Sarcoma	Connective And Soft Tissue Neoplasm Tumor Of Soft Tissue And Skeleton Sarcomas Sarcoma - Category
Meningioma, Familial	Meningioma Familial Meningioma Meningioma, Familial, Susceptibility To Meningeal Neoplasm Meningeal Neoplasms Meningiomas Meningioma, Nf2-Related, Somatic Meningioma, Sis-Related Meningothelial Cell Tumor Neoplasm Of The Meninges Primary Meningeal Tumor Familial Multiple Meningioma MNGMA Meningioma, Benign, No Icd-O Subtype Intracranial Meningioma Meningothelial Cell Neoplasm Supratentorial Meningioma Primary Neoplasm Of Spinal Meninges Benign Intracranial Meningioma Benign Meningioma Meningeal Tumours Meningeal Sarcoma Of Unspecified Site Meningothelial Sarcoma Of Unspecified Site
Retinitis Pigmentosa 67	RP67 Retinitis Pigmentosa, Type 67
Wiskott-Aldrich Syndrome	WAS Eczema-Thrombocytopenia-Immunodeficiency Syndrome Immunodeficiency 2 Aldrich Syndrome Imd2 Wiskott-Aldrich Syndrome 1 Was1 Wiskott Syndrome Wiskott Aldrich Syndrome Eczema Thrombocytopenia Immunodeficiency Syndrome Imd 2
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Polycythemia Vera	PV Polycythemia Rubra Vera Prv Osler-Vaquez Disease Chronic Erythremia Polycythaemia Rubra Vera Primary Polycythemia Vaquez Disease Polycythemia Vera, Somatic Osler-Vaquez Syndrome Proliferative Polycythaemia Polycythemia Ruba Vera Acquired Primary Erythrocytosis Heilmeyer-Schoner Disease Vaquez Osler Disease Primary Polycythaemia
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Melanoma	Malignant Melanoma Cutaneous Melanoma Naevocarcinoma Malignant Melanomas
Maturity-Onset Diabetes Of The Young	MODY Maturity Onset Diabetes Mellitus In Young Mason-Type Diabetes Mason Type Diabetes Maturity Onset Diabetes Of The Young Mody Syndrome Diabetes Of The Young, Maturity-Onset
Polycystic Kidney Disease	Polycystic Kidney Diseases Pkd Polycystic Renal Disease Kidney Disease, Polycystic Polycystic Kidney, Autosomal Dominant
Amelogenesis Imperfecta	Ai Congenital Enamel Hypoplasia Al - [Amelogenesis Imperfecta]
Noonan Syndrome With Multiple Lentigines	Leopard Syndrome Multiple Lentigines Syndrome Moynahan Syndrome Cardiomyopathic Lentiginosis Progressive Cardiomyopathic Lentiginosis Cardio-Cutaneous Syndrome Lentiginosis Profusa Capute-Rimoin-Konigsmark-Esterly-Richardson Syndrome Generalized Lentiginosis Gorlin Syndrome Ii Lentiginosis Profusa Syndrome Lentigines, Electrocardiographic Conduction Abnormalities, Ocular Hypertelorism, Pulmonic Stenosis, Abnormal Genitalia, Retardation Of Growth, Deafnes Diffuse Lentiginosis Nsml Familial Multiple Lentigines Syndrome Alopecia-Epilepsy-Intellectual Disability Syndrome, Moynahan Type Progressive Cardiomyopathic Lentiginosis Syndrome Alopecia Epilepsy Oligophrenia Syndrome Of Moynahan
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Leukemia, Myeloid, Acute Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Amelogenesis Imperfecta, Type Ig	Enamel-Renal Syndrome Ers Amelogenesis Imperfecta Type 1g AI1G Enamel-Renal-Gingival Syndrome Amelogenesis Imperfecta And Gingival Fibromatosis Syndrome Aigfs Amelogenesis Imperfecta, Hypoplastic, With Nephrocalcinosis Amelogenesis Imperfecta Hypoplastic With Nephrocalcinosis Amelogenesis Imperfecta Type Ig Amelogenesis Imperfecta-Nephrocalcinosis Syndrome Amelogenesis Imperfecta 1g Hypoplastic Amelogenesis Imperfecta With Nephrocalcinosis Amelogenesis Imperfecta Nephrocalcinosis
Tetanus	Lockjaw Clostridial Tetanus Infection Due To Clostridium Tetani Lock-Jaw
46,Xy Sex Reversal 1	SRXY1 46,Xy Gonadal Dysgenesis, Complete, Sry-Related 46,Xy Sex Reversal, Sry-Related Swyer Syndrome 46xy Sex Reversal 1 46,Xy Gonadal Dysgenesis Complete Sry-Related 46,Xy Sex Reversal Sry-Related 46,Xy True Hermaphroditism Sry-Related Gonadal Dysgenesis Xy Female Type Xy Females 46,Xy True Hermaphroditism, Sry-Related Gonadal Dysgenesis, 46,Xy 46, Xy Female
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Obesity , Susceptibility To Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Coenzyme Q10 Deficiency, Primary, 1	COQ10D1 Ubiquinone Deficiency 1 Coenzyme Q Deficiency 1 Coq Deficiency 1 Coq10 Deficiency, Primary, 1 Primary Coenzyme Q10 Deficiency 1 Primary Coq10 Deficiency 1 Coenzyme Q10 Deficiency, Primary, Type 1
Osteopetrosis	Albers-Schonberg Disease Marble Bone Disease Osteopetroses Marble Bones Osteopetrosis And Related Disorders Congenital Osteopetrosis Marble Bone Albers-Schoenberg Disease Albers-Schonberg Osteopetrosis Osteosclerosis Fragilis Ivory Bones

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (11)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10181	Dasatinib	Inhibitor	99.85%	Yes
HY-12047	Ponatinib	Inhibitor	99.67%	Yes
HY-10158	Bosutinib	Inhibitor	99.97%	Yes
HY-10181A	Dasatinib hydrochloride	Inhibitor	99.67%	Yes
HY-10340	Tirbanibulin	Inhibitor	99.45%	Unkown
HY-10209	Masitinib	Inhibitor	99.94%	Yes
HY-108766	Ponatinib hydrochloride	Inhibitor	99.76%	Yes
HY-10181B	Dasatinib monohydrate	Inhibitor	99.58%	Yes
HY-10209A	Masitinib mesylate	Inhibitor	99.98%	Yes
HY-10158A	Bosutinib hydrate	Inhibitor	99.97%	Yes
HY-10340B	Tirbanibulin Mesylate	Inhibitor	99.94%	Unkown

Clinical Phase

Bioactive Molecules (18)

Cat. No.	Product Name	Effect	Purity	Phase
HY-10234	Saracatinib	Inhibitor	99.23%	Phase 3
HY-10234A	Saracatinib difumarate	Inhibitor	99.93%	Phase 3
HY-10340A	Tirbanibulin dihydrochloride	Inhibitor	98.02%	Phase 3
HY-13024	Rebastinib	Inhibitor	99.84%	Phase 2
HY-50868	Bafetinib	Inhibitor	99.18%	Phase 2
HY-59047	Tolimidone	Activator	99.98%	Phase 2
HY-32718	Pelitinib	Inhibitor	99.13%	Phase 2
HY-15323	PRT062607 Hydrochloride	Inhibitor	98.07%	Phase 2
HY-10987A	ENMD-2076	Inhibitor	99.99%	Phase 2
HY-10186	TG 100801	Inhibitor	98.61%	Phase 2
HY-10987	ENMD-2076 Tartrate	Inhibitor	99.66%	Phase 2
HY-10187	TG 100801 Hydrochloride	Inhibitor	/	Phase 2
HY-157442	GLPG3312	Inhibitor	98.63%	Phase 1
HY-10032	PF 477736	Inhibitor	99.04%	Phase 1
HY-111787	Elzovantinib	Inhibitor	99.93%	Phase 1
HY-15749	XL228	Inhibitor	99.64%	Phase 1
HY-112809	GSK2646264	Inhibitor	99.74%	Phase 1
HY-112314	AZD0424	Inhibitor	/	Phase 1

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P991664	AG01	Inhibitor	95.10%	Phase 1

Pre-clinical Phase

Bioactive Molecules (273)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13805	PP2	Inhibitor	99.14%	Unkown
HY-15176A	Pyridostatin hydrochloride	Inhibitor	99.95%	Unkown
HY-N0752	Scutellarein	Inhibitor	99.39%	Unkown
HY-12299	WH-4-023	Inhibitor	99.87%	Unkown
HY-101053	Src Inhibitor 1	Inhibitor	99.97%	Unkown
HY-112096	eCF506	Inhibitor	99.77%	Unkown
HY-B0789	SU6656	Inhibitor	99.01%	Unkown
HY-N7264	7α-Hydroxycholesterol		99.99%	Unkown
HY-N0031	Plantamajoside		99.80%	Unkown
HY-W062835	CGP77675	Inhibitor	99.46%	Unkown
HY-135299	CH6953755	Inhibitor	99.75%	Unkown
HY-12072	Lck Inhibitor	Inhibitor	99.65%	Unkown
HY-11011	A-770041	Inhibitor	99.89%	Unkown
HY-15764	A 419259	Inhibitor	99.88%	Unkown
HY-130254	CSK-IN-1	Inhibitor	98.61%	Unkown
HY-10395	PD173955	Inhibitor	99.12%	Unkown
HY-15764A	A 419259 trihydrochloride	Inhibitor	98.28%	Unkown
HY-132166	Velzatinib	Inhibitor	99.40%	Unkown
HY-13804	PP1	Inhibitor	99.57%	Unkown
HY-15176B	Pyridostatin TFA	Inhibitor	99.17%	Unkown
HY-13942	1-NM-PP1	Inhibitor	98.93%	Unkown
HY-136848	SM1-71	Inhibitor	96.09%	Unkown
HY-N0202	Atractylenolide II	Inhibitor	99.89%	Unkown
HY-112852	TL02-59	Inhibitor	99.86%	Unkown
HY-W040055	Neopterin	Inhibitor	99.95%	Unkown
HY-13941	1-Naphthyl PP1	Inhibitor	99.36%	Unkown
HY-139147	iHCK-37	Inhibitor	99.52%	Unkown
HY-122113	PD173952	Inhibitor	99.58%	Unkown
HY-10372	PP121	Inhibitor	99.51%	Unkown
HY-P3279	EPQpYEEIPIYL	Activator	99.49%	Unkown
HY-118144	PD166326	Inhibitor	99.99%	Unkown
HY-121705	Propionyl-L-carnitine	Activator	95.0%	Unkown
HY-18303	AMG-47a	Inhibitor	99.19%	Unkown
HY-100434	PD-161570	Inhibitor	99.82%	Unkown
HY-12039	Lyn-IN-1	Inhibitor	98.07%	Unkown
HY-78263	MNS	Inhibitor	99.55%	Unkown
HY-108318	RK-24466	Inhibitor	99.91%	Unkown
HY-148385	Ganglioside GM2	Activator	98.0%	Unkown
HY-N0442	5-O-Methylvisammioside	Inhibitor	99.90%	Unkown
HY-N0701	(-)-Asarinin	Inhibitor	99.90%	Unkown
HY-155657	BT424	Inhibitor	98.89%	Unkown
HY-101963	AD80	Inhibitor	99.88%	Unkown
HY-159480	AD1058	Inhibitor	98.11%	Unkown
HY-108488	KB SRC 4	Inhibitor	99.22%	Unkown
HY-120417	JP-153	Inhibitor	99.45%	Unkown
HY-136605	DGY-06-116	Inhibitor	98.62%	Unkown
HY-N0909	Notoginsenoside R2	Inhibitor	99.80%	Unkown
HY-163144	DAS-5-oCRBN	Degrader	99.21%	Unkown
HY-101795	Larixyl acetate	Inhibitor	99.44%	Unkown
HY-131669	Dasatinib metabolite M6	Inhibitor	99.39%	Unkown
HY-18622	PP58	Inhibitor	98.70%	Unkown
HY-15805	KIN-8194	Inhibitor	99.26%	Unkown
HY-10181S	Dasatinib-d8	Inhibitor	99.15%	Unkown
HY-112182	UM-164	Inhibitor	98.74%	Unkown
HY-13561	AZM475271	Inhibitor	99.89%	Unkown
HY-146127A	Grb2 SH2 domain inhibitor 1 TFA	Inhibitor	99.62%	Unkown
HY-108016	Peruvoside	Inhibitor	99.32%	Unkown
HY-10185	TG 100572 Hydrochloride	Inhibitor	98.76%	Unkown
HY-107447	N-Deshydroxyethyl Dasatinib	Ligand	97.19%	Unkown
HY-107024	Osteogenic Growth Peptide (10-14)	Inhibitor	99.51%	Unkown
HY-103274	PD180970	Inhibitor	99.27%	Unkown
HY-15176C	Pyridostatin trihydrochloride	Inhibitor	99.85%	Unkown
HY-13314	Tesevatinib	Inhibitor	99.41%	Yes
HY-112291	SB 220025	Inhibitor	99.90%	Unkown
HY-137345	DB-3-291	Degrader	99.08%	Unkown
HY-127002	Squarunkin A	Inhibitor	99.49%	Unkown
HY-N4201	β-Hydroxyisovalerylshikonin	Inhibitor	99.83%	Unkown
HY-N6596	7-Hydroxy-4H-chromen-4-one	Inhibitor	99.85%	Unkown
HY-15814	HG-7-85-01	Inhibitor	98.14%	Unkown
HY-120595	JNJ-49095397	Inhibitor	99.55%	Unkown
HY-108485	Damnacanthal	Inhibitor	99.40%	Unkown
HY-N4127	3'-Demethylnobiletin		99.98%	Unkown
HY-13342AS	Apatinib-d8 free base		92.5%	Unkown
HY-P6442	Chemerin15	Inhibitor	99.65%	Unkown
HY-137342	SB1-G-187	Degrader	98.70%	Unkown
HY-13941B	1-Naphthyl PP1 hydrochloride	Inhibitor	99.83%	Unkown
HY-10644	Lck inhibitor 2	Inhibitor	99.73%	Unkown
HY-137918	TGF-βRI inhibitor 3	Inhibitor	99.16%	Unkown
HY-120213	YH-306	Inhibitor	98.34%	Unkown
HY-155582	BLK degrader 1	Degrader	98.94%	Unkown
HY-N7160	2-Hydroxy-3-methylanthraquinone	Inhibitor	99.60%	Unkown
HY-132150A	HPK1-IN-2 dihydrochloride	Inhibitor	98.03%	Unkown
HY-15324	PRT062607 acetate	Inhibitor	99.83%	Unkown
HY-18507	AD57	Inhibitor	98.27%	Unkown
HY-W013857	Lavendustin C	Inhibitor	98.17%	Unkown
HY-163469	SRC-3-IN-2	Inhibitor	96.32%	Unkown
HY-111187	KX2-361	Inhibitor	99.09%	Unkown
HY-N0046	Notoginsenoside Fe	Inhibitor	99.99%	Unkown
HY-P1377A	Caffeic acid-pYEEIE TFA		98.47%	Unkown
HY-18623	VI 16832	Ligand	99.09%	Unkown
HY-W744699	Larixol	Inhibitor	95.52%	Unkown
HY-125028	Hck-IN-1	Inhibitor	98.10%	Unkown
HY-176892A	Papaveroline hydrochloride	Inhibitor	99.04%	Unkown
HY-P1111	Lyn peptide inhibitor	Inhibitor	99.35%	Unkown
HY-122949	Momordicine I	Inhibitor	97.0%	Unkown
HY-136849	TL13-68	Inhibitor	98.31%	Unkown
HY-175451	MRT-10350	Degrader	99.10%	Unkown
HY-123298	Chrysotoxine	Inhibitor	99.52%	Unkown
HY-P10665	pYEEI	Inhibitor	99.01%	Unkown
HY-P2547A	Tyrosine Kinase Peptide 1 acetate		99.51%	Unkown
HY-148066	DB0662	Degrader	99.66%	Unkown
HY-102073	TG53	Inhibitor	98.6%	Unkown
HY-176461	Pro-Dasatinib	Inhibitor	/	Unkown
HY-12847	CCT241161	Inhibitor	99.77%	Unkown
HY-156914	IGF-1R/SRC-IN-1	Inhibitor	99.86%	Unkown
HY-147314	HIV-IN-6		98.14%	Unkown
HY-112345	PD-089828	Inhibitor	98.07%	Unkown
HY-137343	DB-0646	Degrader	98.0%	Unkown
HY-15764G	A 419259 (GMP)	Inhibitor	/	Unkown
HY-162676	SJ45566	Degrader	98.41%	Unkown
HY-153556	GW297361	Inhibitor	98.13%	Unkown
HY-12047S	Ponatinib-d8	Inhibitor	99.16%	Unkown
HY-10158S	Bosutinib-d8	Inhibitor	≥99.0%	Unkown
HY-16906	T338C Src-IN-2	Inhibitor	98.41%	Unkown
HY-176892	Papaveroline	Inhibitor	/	Unkown
HY-P11147	IL13Rα2 D1	Inhibitor	99.17%	Unkown
HY-116028	15-deoxy-Δ12,14-Prostaglandin D2	Activator	98.0%	Unkown
HY-123506	Fenlean	Inhibitor	99.56%	Unkown
HY-155587	Hydroxy-PP	Inhibitor	99.66%	Unkown
HY-10181G	Dasatinib (GMP)	Inhibitor	/	Unkown
HY-180888	Lck-IN-5	Inhibitor	98.09%	Unkown
HY-138202	Lck-IN-1	Inhibitor	98.54%	Unkown
HY-179433	PROTAC AR Degrader-12	Inhibitor	/	Unkown
HY-13805R	PP2 (Standard)	Inhibitor	99.05%	Unkown
HY-10181S1	Dasatinib-d4	Inhibitor	97.54%	Unkown
HY-10184	TG 100572	Inhibitor	/	Unkown
HY-18237	KX1-004	Inhibitor	99.75%	Unkown
HY-108649A	MRS2768 tetrasodium salt	Activator	98.70%	Unkown
HY-117123	Convulxin	Activator	/	Unkown
HY-118105	RK-20448	Inhibitor	99.38%	Unkown
HY-16905	T338C Src-IN-1	Inhibitor	/	Unkown
HY-10158S1	Bosutinib-13C,d3	Inhibitor	/	Unkown
HY-181050	DFCI-002-06	Degrader	/	Unkown
HY-13024A	Rebastinib tosylate	Inhibitor	/	Unkown
HY-112852A	TL02-59 dihydrochloride	Inhibitor	/	Unkown
HY-157998	mG2N001		/	Unkown
HY-P2547	Tyrosine Kinase Peptide 1		/	Unkown
HY-P3771	p60c-src substrate II, phosphorylated		/	Unkown
HY-175298	STAT-3/c-Src-IN-1	Inhibitor	/	Unkown
HY-170958	Scr-IN-1	Inhibitor	/	Unkown
HY-121828	TX-1123	Inhibitor	/	Unkown
HY-162879	FAK inhibitor 7	Inhibitor	/	Unkown
HY-180928	LCK degrader-3	Degrader	/	Unkown
HY-112393	TX-1918	Inhibitor	/	Unkown
HY-178950	Hck-IN-3	Inhibitor	/	Unkown
HY-176194	Antifibrotic agent 1	Inhibitor	/	Unkown
HY-131931	Lysoganglioside-GM1 potassium	Inhibitor	/	Unkown
HY-10188	SKS-927	Inhibitor	/	Unkown
HY-163468	SRC-3-IN-1	Inhibitor	/	Unkown
HY-162291	Lck-IN-3	Inhibitor	/	Unkown
HY-10363	AP 24149	Inhibitor	/	Unkown
HY-E70726	FYN Y531F Recombinant Human Active Protein Kinase		/	Unkown
HY-175916	LCK ligand-1	Ligand	/	Unkown
HY-160167	Birelentinib	Inhibitor	/	Unkown
HY-18692	Multi-kinase-IN-12	Inhibitor	/	Unkown
HY-183584	ARN25699	Inhibitor	/	Unkown
HY-P3743	p60c-src Substrate		/	Unkown
HY-157290	HL403	Inhibitor	/	Unkown
HY-P1111A	Lyn peptide inhibitor TFA	Inhibitor	/	Unkown
HY-112096S	eCF506-d5	Inhibitor	/	Unkown
HY-10158AR	Bosutinib hydrate (Standard)	Inhibitor	/	Unkown
HY-125387	TOP1210		/	Unkown
HY-185227	EphB4-IN-1	Inhibitor	/	Unkown
HY-P1200	Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH	Inhibitor	/	Unkown
HY-P0200	RR-SRC		/	Unkown
HY-115723	Antiallergic agent-1	Inhibitor	/	Unkown
HY-184274	EGFR/c-SRC-IN-1	Chemical	/	Unkown
HY-128397	CpCDPK1/TgCDPK1-IN-1	Inhibitor	/	Unkown
HY-175280	Lck degrader-1	Degrader	/	Unkown
HY-168901	Hck-IN-2	Inhibitor	/	Unkown
HY-180938	Fyn-IN-1	Inhibitor	/	Unkown
HY-175463	LCK degrader-2	Degrader	/	Unkown
HY-135216	Antiproliferative agent-54	Inhibitor	/	Unkown
HY-181732	PROTAC TG2 Degrader-3	Modulator	/	Unkown
HY-W844558	Protein kinase inhibitor 11	Inhibitor	98.28%	Unkown
HY-131931A	Lysoganglioside-GM1 ammonium	Inhibitor	/	Unkown
HY-15268	PP487	Inhibitor	/	Unkown
HY-W062835A	CGP77675 hydrate	Inhibitor	/	Unkown
HY-P10527	CSK substrate		/	Unkown
HY-139890	DC-Srci-6649	Inhibitor	/	Unkown
HY-175193	N-Deshydroxyethyl Dasatinib-C3-NH2	Inhibitor	/	Unkown
HY-114980	BMS-279700	Inhibitor	/	Unkown
HY-112448	Lck-IN-6	Inhibitor	/	Unkown
HY-170971	Src Inhibitor 4	Inhibitor	/	Unkown
HY-112335	Lck Inhibitor III	Inhibitor	/	Unkown
HY-12299G	WH-4-023 (GMP)	Inhibitor	/	Unkown
HY-10181GL	Dasatinib (GMP Like)	Inhibitor	/	Unkown
HY-162413	(R)-LW-Srci-8	Inhibitor	/	Unkown
HY-E70725	FRK Recombinant Human Active Protein Kinase		/	Unkown
HY-101268	CHMFL-ABL-053	Inhibitor	/	Unkown
HY-P10372	pFYN peptide		/	Unkown
HY-P2372	P60v-src(137-157)	Inhibitor	/	Unkown
HY-P1377	Caffeic acid-pYEEIE		/	Unkown
HY-127002A	Squarunkin A hydrochloride	Inhibitor	/	Unkown
HY-138195	NEO212	Inhibitor	/	Unkown
HY-178120	Lck-IN-4	Inhibitor	/	Unkown
HY-108649	MRS2768	Activator	/	Unkown
HY-182614	BJ-2302	Inhibitor	/	Unkown
HY-W745090	Isomaltulose monohydrate	Inhibitor	/	Unkown
HY-110367	LCB 03-0110 dihydrochloride	Inhibitor	/	Unkown
HY-108487	N-Acetyl-O-phosphono-Tyr-Glu dipentylamide	Inhibitor	/	Unkown
HY-168893	K882	Inhibitor	/	Unkown
HY-123394	AP-22161	Inhibitor	/	Unkown
HY-132150C	HPK1-IN-2 TFA	Inhibitor	/	Unkown
HY-180834	Tyrosine kinase-IN-11	Inhibitor	98.75%	Unkown
HY-182293	BTK-IN-48	Inhibitor	/	Unkown
HY-175281	SJ11646	Degrader	/	Unkown
HY-168187	Src Inhibitor 3	Inhibitor	/	Unkown
HY-146014	Multi-kinase-IN-1	Inhibitor	/	Unkown
HY-E70862	Src-ZAP70 Recombinant Human Active Protein Kinase		/	Unkown
HY-W769935	5-POHSA	Modulator	/	Unkown
HY-18507A	AD57 hydrochloride	Inhibitor	/	Unkown
HY-175845	Scr-IN-2	Inhibitor	/	Unkown
HY-125500	TOP1362	Inhibitor	/	Unkown
HY-177272	HPK1-IN-61	Inhibitor	/	Unkown
HY-110367A	LCB 03-0110	Inhibitor	/	Unkown
HY-150026	Multi-kinase-IN-2	Inhibitor	/	Unkown
HY-100824	PP2 Analog	Inhibitor	/	Unkown
HY-157497	DA5-HTL	Inhibitor	98.69%	Unkown
HY-163278	Lck-IN-2	Inhibitor	/	Unkown
HY-175809	SRT6	Inhibitor	/	Unkown
HY-125142	AP-24567	Inhibitor	/	Unkown
HY-183103	PDD-87	Inhibitor	/	Unkown
HY-179948	BTK-IN-45	Inhibitor	/	Unkown
HY-112404	BCR-ABL-IN-13	Inhibitor	99.86%	Unkown
HY-121849	KL-1156	Inhibitor	/	Unkown
HY-112369	LDDN-0003499	Inhibitor	/	Unkown
HY-125718	MLS-2384 free base	Inhibitor	/	Unkown
HY-184792	CA/PRAK-IN-1	Inhibitor	/	Unkown
HY-101447	SI-2	Inhibitor	/	Unkown
HY-172096	cSRC/BCR-ABL-IN-1	Inhibitor	/	Unkown
HY-161687	Cisplatin/Dasatinib prodrug-1	Inhibitor	/	Unkown
HY-P3773	p60c-src substrate II		/	Unkown
HY-P1200A	Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA	Inhibitor	/	Unkown
HY-122860	SKLB-C05		/	Unkown
HY-13314A	Tesevatinib tosylate	Inhibitor	/	Unkown
HY-116028S1	15-deoxy-Δ12,14-Prostaglandin D2-d4	Activator	/	Unkown
HY-136699	Excisanin A	Inhibitor	/	Unkown
HY-176367	Multi kinase ligand 4	Inhibitor	/	Unkown
HY-W714853	(+)-Theta-cypermethrin	Ligand	/	Unkown
HY-P2413	Ac-PPPHPHARIK-NH2	Inhibitor	/	Unkown
HY-175437	MRT-7612	Degrader	/	Unkown
HY-149921	Antiangiogenic agent 3	Inhibitor	/	Unkown
HY-176225	BY13	Degrader	/	Unkown
HY-136622	A-420983	Inhibitor	/	Unkown
HY-N14279	Hibarimicin G	Inhibitor	/	Unkown
HY-120622	BMS-243117	Inhibitor	/	Unkown
HY-10234S	Saracatinib-d3	Inhibitor	/	Unkown
HY-32718S	Pelitinib-d6		/	Unkown
HY-112852S	TL02-59-d5		/	Unkown
HY-N14273	Hibarimicin C	Inhibitor	/	Unkown
HY-160930	TOP1288	Inhibitor	/	Unkown
HY-N15076	Herbimycin B	Inhibitor	/	Unkown
HY-N14618	Rhodomycin A	Inhibitor	/	Unkown
HY-169670	Protein kinase inhibitor 13	Inhibitor	/	Unkown
HY-125064	AP22408	Inhibitor	/	Unkown
HY-133184	Aminogenistein	Inhibitor	/	Unkown
HY-N0442R	5-O-Methylvisammioside (Standard)	Inhibitor	/	Unkown
HY-171217	TG-100435	Inhibitor	/	Unkown
HY-N12166	2,3,4,6,8-Pentahydroxy-1-methylxanthone	Inhibitor	/	Unkown
HY-122585	proMMP-9 inhibitor-3c	Inhibitor	/	Unkown
HY-W994722	ISO24	Ligand	/	Unkown
HY-W700620	Hydroxymethyl dasatinib	Inhibitor	99.92%	Unkown
HY-D3058	FITC-amide-C2 Lck inhibitor 2	Inhibitor	/	Unkown
HY-N14271	Hibarimicin B	Inhibitor	/	Unkown
HY-18909	Multi-kinase-IN-11	Inhibitor	/	Unkown
HY-164527	Si306	Inhibitor	/	Unkown
HY-N14267	Hibarimicin A	Inhibitor	/	Unkown
HY-164530	SKLB646	Inhibitor	/	Unkown
HY-178014	SIK1-IN-1	Inhibitor	/	Unkown
HY-171218	CGP062464	Inhibitor	/	Unkown
HY-112291A	SB 220025 (tri(hydrochloride))	Inhibitor	/	Unkown
HY-N14689	Hibarimicin D	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SRC	MGD	MGI:98397
Canis familiaris	SRC	VGNC	VGNC:46791
Macaca mulatta	SRC	VGNC	VGNC:77878
Felis catus	SRC	VGNC	VGNC:65671
Bos taurus	SRC	VGNC	VGNC:35269
Rattus norvegicus	SRC	RGD	RGD:620795
Others	SRC	NCBI