HDAC6 - histone deacetylase 6 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 108348065

About HDAC6

Primary_assembly X: 14,551,044-14,572,441 forward strand.mRatBN7.2:CM026994.1

This gene has 3 transcripts (splice variants), 182 orthologues, 12 paralogues and is associated with 19 phenotypes.

Summary

Enables deacetylase activity. Involved in several processes, including generation of neurons; regulation of protein modification process; and response to glucocorticoid. Located in axon and centrosome. Used to study polycystic kidney disease and polycystic liver disease. Biomarker of hypertension and polycystic liver disease. Human ortholog(s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Orthologous to human HDAC6 (histone deacetylase 6). [provided by Alliance of Genome Resources, Apr 2022]

HDAC6 Products (4)

mRNA Protein Name
XM_006256758.3 XP_006256820.1 histone deacetylase 6
XM_003752010.4 XP_003752058.1 histone deacetylase 6
XM_039100468.1 XP_038956396.1 histone deacetylase 6
XM_006256759.4 XP_006256821.1 histone deacetylase 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables deacetylase activity IDA
IDA: Inferred from direct assay
23868068 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
19167333 RGD
Biological Process GO Annotation Evidence References Source
involved in axonal transport of mitochondrion IMP
IMP: Inferred from mutant phenotype
22937007 RGD
involved in cellular response to parathyroid hormone stimulus IEP
IEP: Inferred from expression pattern
20097749 RGD
involved in negative regulation of axon extension involved in axon guidance IMP
IMP: Inferred from mutant phenotype
19884510 RGD
involved in negative regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
19884510 RGD
involved in negative regulation of protein acetylation IMP
IMP: Inferred from mutant phenotype
24464872 RGD
involved in neuron differentiation IEP
IEP: Inferred from expression pattern
12850547 RGD
involved in positive regulation of cellular response to oxidative stress IMP
IMP: Inferred from mutant phenotype
19884510 RGD
involved in positive regulation of cholangiocyte proliferation IMP
IMP: Inferred from mutant phenotype
24434010 RGD
involved in positive regulation of dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
19167333 RGD
involved in positive regulation of synaptic transmission, glutamatergic IMP
IMP: Inferred from mutant phenotype
22331421 RGD
involved in positive regulation of tubulin deacetylation IMP
IMP: Inferred from mutant phenotype
24464872 RGD
involved in regulation of microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
24464872 RGD
involved in regulation of mitochondrion organization IMP
IMP: Inferred from mutant phenotype
22937007 RGD
involved in regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
24464872 RGD
involved in response to amphetamine IEP
IEP: Inferred from expression pattern
25452209 RGD
involved in response to corticosterone IMP
IMP: Inferred from mutant phenotype
22331421 RGD
involved in response to dexamethasone IEP
IEP: Inferred from expression pattern
20538901 RGD
involved in response to immobilization stress IEP
IEP: Inferred from expression pattern
17316384 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
22937007 RGD
located in centrosome IDA
IDA: Inferred from direct assay
19167333 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HDAC6 Protein Structure

Arginase_HDAC

Arginase_HDAC: cl17011 (97 - 433)

HDAC6-dom2

HDAC6-dom2: cd10003 (483 - 833)

zf-UBP

zf-UBP: pfam02148 (1069 - 1131)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1152 a.a.
Protein Preferred Names Protein Names

histone deacetylase 6

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15149 Romidepsin Inhibitor 99.98% Unkown
HY-10225 Belinostat Inhibitor 99.97% Yes
HY-14842 Givinostat Inhibitor 98.67% Yes
HY-13322 Pracinostat Inhibitor 99.80% Yes
HY-14842B Givinostat hydrochloride monohydrate Inhibitor 99.63% Yes
HY-B0494 Bufexamac Inhibitor 98.47% Unkown
HY-14842A Givinostat hydrochloride Inhibitor 98.06% Yes

Clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Phase
HY-14718 Resminostat Inhibitor 99.44% Phase 4
HY-10990 Abexinostat Inhibitor 99.00% Phase 3
HY-101780 Tinostamustine Inhibitor 99.64% Phase 3
HY-150109 Puzerinostat mesylate Inhibitor 99.45% Phase 3
HY-175513 ZWZH-21 Inhibitor / Phase 3
HY-16026 Ricolinostat Inhibitor 99.83% Phase 2
HY-15433 Quisinostat Inhibitor 99.71% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-13432 Nanatinostat Inhibitor 99.67% Phase 2
HY-138799 KA2507 Inhibitor 99.17% Phase 2
HY-124295 Imofinostat Inhibitor 99.40% Phase 2
HY-184424 HDAC6-IN-84 Inhibitor / Phase 2
HY-10223 CUDC-101 Inhibitor 99.05% Phase 1
HY-15994 Citarinostat Inhibitor 99.55% Phase 1

Pre-clinical Phase

Bioactive Molecules (305)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13271A Tubastatin A Inhibitor 99.07% Unkown
HY-18361 TMP195 Inhibitor 99.82% Unkown
HY-N0931 Santacruzamate A Inhibitor 99.54% Unkown
HY-15224 PCI-34051 Inhibitor 99.84% Unkown
HY-13428 Tubacin Inhibitor 98.71% Unkown
HY-13271 Tubastatin A Hydrochloride Inhibitor 99.31% Unkown
HY-18998 LMK-235 Inhibitor 99.61% Unkown
HY-18360 TMP269 Inhibitor 98.16% Unkown
HY-16699 Nexturastat A Inhibitor 98.69% Unkown
HY-19327 ACY-738 Inhibitor 99.92% Unkown
HY-18613 CAY10603 Inhibitor 99.76% Unkown
HY-15433A Quisinostat dihydrochloride Inhibitor 99.05% Unkown
HY-153392 TYA-018 Inhibitor 99.84% Unkown
HY-111400 SR-4370 Inhibitor 98.38% Unkown
HY-103596 Thalidomide-4-OH Degrader 99.62% Unkown
HY-N0071 Crotonoside Inhibitor 99.78% Unkown
HY-111818 TH34 Inhibitor 99.52% Unkown
HY-19328 ACY-775 Inhibitor 99.71% Unkown
HY-144779 HDAC10-IN-1 Inhibitor 99.87% Unkown
HY-111791 ACY-1083 Inhibitor 99.61% Unkown
HY-13267 Droxinostat Inhibitor 99.08% Unkown
HY-119939 CHDI-390576 Inhibitor 98.10% Unkown
HY-161307 T-518 Inhibitor 98.40% Unkown
HY-115475 SW-100 Inhibitor 99.93% Unkown
HY-126330 SS-208 Inhibitor 99.00% Unkown
HY-123295 HDAC3-IN-T247 Inhibitor 98.91% Unkown
HY-18976 UF010 99.83% Unkown
HY-161305 SE-7552 Inhibitor 99.48% Unkown
HY-164099 LSD1/HDAC6-IN-2 Inhibitor 99.66% Unkown
HY-169259 HDAC9-IN-1 Inhibitor 95.13% Unkown
HY-114414 HDACs/mTOR Inhibitor 1 Inhibitor 98.10% Unkown
HY-126147 J22352 Inhibitor 99.04% Unkown
HY-123976 MPT0G211 Inhibitor 99.79% Unkown
HY-173266A TO-1187 TFA Degrader 98.41% Unkown
HY-18712 BG45 Inhibitor 99.95% Unkown
HY-14718A Resminostat hydrochloride Inhibitor 99.67% Yes
HY-135714 Bavarostat Inhibitor 99.51% Unkown
HY-171139 PROTAC HDAC6 degrader 2 Inhibitor 99.80% Unkown
HY-130493 HPB Inhibitor 99.11% Unkown
HY-116818 Crebinostat Inhibitor 98.83% Unkown
HY-171140 PROTAC HDAC6 degrader 3 Degrader 99.81% Unkown
HY-158075 DNMT/HDAC-IN-1 Inhibitor 99.87% Unkown
HY-100871 WT-161 Inhibitor 98.04% Unkown
HY-135890 CG347B Inhibitor 98.07% Unkown
HY-152134 PROTAC HDAC6 degrader 11 Degrader 98.12% Unkown
HY-124053 BRD2492 Inhibitor 99.22% Unkown
HY-150109A Puzerinostat Inhibitor 98.04% Unkown
HY-114483 AES-135 Inhibitor 98.68% Unkown
HY-19747 HPOB Inhibitor 99.54% Unkown
HY-170495 HDAC6 degrader-5 Inhibitor 99.55% Unkown
HY-156027 SIRT6-IN-3 Inhibitor 98.19% Unkown
HY-161304 HDAC6-IN-33 Inhibitor 98.96% Unkown
HY-18700 BRD73954 Inhibitor 99.13% Unkown
HY-171141 HDAC6 ligand-2 Ligand 98.70% Unkown
HY-156850 ITF 3756 Inhibitor 98.55% Unkown
HY-126141 JAK/HDAC-IN-1 Inhibitor 98.63% Unkown
HY-162616 SelSA Inhibitor 99.83% Unkown
HY-110280 MC1742 Inhibitor 98.95% Unkown
HY-131708A FNDR-20123 Inhibitor 98.08% Unkown
HY-159109 HDAC6-IN-46 Inhibitor 98.51% Unkown
HY-130538 1-Naphthohydroxamic acid Inhibitor 99.59% Unkown
HY-149721 HDAC4-IN-1 Inhibitor 98.11% Unkown
HY-178948A HDAC10-IN-3 formic Inhibitor 97.16% Unkown
HY-178948 HDAC10-IN-3 Inhibitor / Unkown
HY-12954 PTACH Inhibitor 99.65% Unkown
HY-146153 HDAC-IN-40 Inhibitor 98.71% Unkown
HY-148624 CHDI-00484077 Inhibitor 98.38% Unkown
HY-124782 HDAC8-IN-8 Inhibitor 99.01% Unkown
HY-138831 AES-350 Inhibitor 99.30% Unkown
HY-117554 BRD9757 Inhibitor 99.75% Unkown
HY-19754A CRA-026440 hydrochloride Inhibitor 98.12% Unkown
HY-173266 TO-1187 Degrader / Unkown
HY-120448A QTX125 TFA Inhibitor 99.93% Unkown
HY-149208 HDAC-IN-53 Inhibitor 95.73% Unkown
HY-120448 QTX125 Inhibitor / Unkown
HY-157740 XSJ-10 Inhibitor 95.16% Unkown
HY-179421 PROTAC HDAC6 degrader 7 Inhibitor / Unkown
HY-151261 HDAC6-IN-13 Inhibitor 98.08% Unkown
HY-169938 LSD1/HDAC-IN-2 Inhibitor / Unkown
HY-174444 PROTAC HDAC degrader-2 Degrader / Unkown
HY-146678 HDAC6-IN-5 Inhibitor / Unkown
HY-131708 FNDR-20123 free base Inhibitor / Unkown
HY-151464 SHP2/HDAC-IN-1 Inhibitor / Unkown
HY-131970 LSD1/HDAC6-IN-1 Inhibitor / Unkown
HY-172177 ROCK/HDAC-IN-2 Inhibitor / Unkown
HY-123976A MPT0G211 mesylate Inhibitor / Unkown
HY-128582 PI3K/HDAC-IN-1 Inhibitor / Unkown
HY-146679 HDAC6-IN-6 Inhibitor / Unkown
HY-163834 HDAC6-IN-47 Inhibitor / Unkown
HY-146276 CDK/HDAC-IN-2 Inhibitor / Unkown
HY-151896 HDAC6-IN-14 Inhibitor / Unkown
HY-180214 HDAC6-IN-69 Inhibitor / Unkown
HY-178104 HDAC-IN-93 Inhibitor / Unkown
HY-172159 FF2039 Inhibitor / Unkown
HY-181541 HIT211504993 Inhibitor / Unkown
HY-15144B (S)-Trichostatin A Inhibitor / Unkown
HY-150595 HDAC6-IN-10 Inhibitor / Unkown
HY-173064 DS-103 Inhibitor / Unkown
HY-187210 HDAC6-IN-86 Inhibitor / Unkown
HY-181805 HDAC6-IN-76 Inhibitor / Unkown
HY-159171 sEH/HDAC6-IN-2 Inhibitor / Unkown
HY-146293 HDAC6/HSP90-IN-1 Inhibitor / Unkown
HY-169400 HDACs/EZH2-IN-1 Inhibitor / Unkown
HY-168175 PROTAC HDAC8 Degrader-2 Degrader / Unkown
HY-144395 HDAC6-IN-4 Inhibitor / Unkown
HY-118160 PPM-18 Inhibitor 99.17% Unkown
HY-181926 COX-2/HDAC6-IN-1 Inhibitor / Unkown
HY-152225 MC2625 Inhibitor / Unkown
HY-181579 HDAC6-IN-74 Inhibitor / Unkown
HY-149372 HDAC6-IN-17 Inhibitor / Unkown
HY-168962 HDAC-IN-88 Inhibitor / Unkown
HY-163368 HDAC6-IN-34 Inhibitor / Unkown
HY-153514 HDAC-IN-54 Inhibitor / Unkown
HY-169226 HDAC6-IN-51 Inhibitor / Unkown
HY-184574 HDAC-IN-104 Inhibitor / Unkown
HY-147934 HDAC8-IN-3 Inhibitor / Unkown
HY-177776 HDAC-IN-97 Degrader / Unkown
HY-174877 PROTAC HDAC6 degrader 6 Degrader / Unkown
HY-169940 Fibrostat Inhibitor / Unkown
HY-119316 CM-414 Inhibitor / Unkown
HY-182777 HDAC6-IN-80 Inhibitor / Unkown
HY-150586 PTG-0861 Inhibitor / Unkown
HY-179654 ST13 Inhibitor / Unkown
HY-175988 DNMT/HDAC-IN-2 Inhibitor / Unkown
HY-187511 NS06 Inhibitor / Unkown
HY-182904 GV-001 Inhibitor / Unkown
HY-184304 HDAC6-IN-83 Inhibitor / Unkown
HY-159172 HDAC3-IN-4 Inhibitor / Unkown
HY-161306 ITF5924 Inhibitor / Unkown
HY-181793 VEGFR2/HDAC-IN-1 Inhibitor / Unkown
HY-124946 C1A Inhibitor / Unkown
HY-179422 HDAC6-IN-68 Inhibitor / Unkown
HY-182747 HDAC6-IN-79 Inhibitor / Unkown
HY-143233 PIM-1/HDAC-IN-1 Inhibitor / Unkown
HY-181678 DNA-PK/HDAC6-IN-1 Inhibitor / Unkown
HY-177758 PROTAC HDAC6 degrader 8 Degrader / Unkown
HY-150503 KH-259 Inhibitor / Unkown
HY-144098 HDAC8-IN-2 Inhibitor / Unkown
HY-169157 HDAC6-IN-50 Inhibitor / Unkown
HY-126566 Trichostatin C Inhibitor / Unkown
HY-173386 HDAC6 ligand-4 Inhibitor / Unkown
HY-163430 HDAC-IN-71 Inhibitor / Unkown
HY-162330 HDAC6-IN-36 Inhibitor / Unkown
HY-163803 CM-444 Inhibitor / Unkown
HY-178110 HDAC6-IN-65 Inhibitor / Unkown
HY-157385 HDAC-IN-67 Inhibitor / Unkown
HY-175628 HDAC6 ligand-Linker Conjugate 2 / Unkown
HY-163894 HDAC6-IN-48 Inhibitor / Unkown
HY-163369 HDAC6-IN-35 Inhibitor / Unkown
HY-146684 HDAC-IN-36 Inhibitor / Unkown
HY-151569 SAHA-OH Inhibitor / Unkown
HY-187212 SH-17 Inhibitor / Unkown
HY-187388 HDAC6/ERα ligand-1 Ligand / Unkown
HY-172360 HDAC6 ligand-3 Ligand / Unkown
HY-172359 PROTAC HDAC6 degrader 4 Degrader / Unkown
HY-145852 Top/HDAC-IN-2 Inhibitor / Unkown
HY-184389 PROTAC HDAC6 degrader 10 Degrader / Unkown
HY-162378 LT-630 Inhibitor / Unkown
HY-144332 PHD2/HDACs-IN-1 Inhibitor / Unkown
HY-162910 HDAC-IN-79 Inhibitor / Unkown
HY-181577 HDAC6-IN-73 Inhibitor / Unkown
HY-176064 HDAC6-IN-58 Inhibitor / Unkown
HY-172200 PD-L1/HDAC6-IN-1 Inhibitor / Unkown
HY-181009 HDAC-IN-98 Inhibitor 98.36% Unkown
HY-150774 HDAC6/HSP90-IN-2 Inhibitor / Unkown
HY-157481 HDAC1-IN-6 Inhibitor / Unkown
HY-175030 TNI-97 Inhibitor / Unkown
HY-174149 HDAC6-IN-59 Inhibitor / Unkown
HY-13432A Nanatinostat TFA Inhibitor / Unkown
HY-180994 HDAC6-IN-72 Inhibitor / Unkown
HY-173184 HDAC6-IN-53 Inhibitor / Unkown
HY-147991 PDE5/HDAC-IN-1 Inhibitor / Unkown
HY-184398 cGAS/HDAC-IN-1 Inhibitor / Unkown
HY-150772 Tubulin/HDAC-IN-1 Inhibitor / Unkown
HY-163207 sEH/HDAC6-IN-1 Inhibitor / Unkown
HY-175627 HDAC6 ligand-6 / Unkown
HY-172394 ZSNI-21 Inhibitor / Unkown
HY-141701 mTOR/HDAC-IN-1 Inhibitor / Unkown
HY-162781 HDAC1/6-IN-2 Inhibitor / Unkown
HY-115941 HDAC-IN-9 Inhibitor / Unkown
HY-151153 HDAC1-IN-5 Inhibitor / Unkown
HY-175176 HDAC1/6-IN-3 Inhibitor / Unkown
HY-183560 HDAC6-IN-82 Inhibitor / Unkown
HY-175467 HDAC6/HSP90-IN-3 Inhibitor / Unkown
HY-181843 HDAC-IN-99 Inhibitor / Unkown
HY-174396 PI3Kδ/HDAC6-IN-1 Inhibitor / Unkown
HY-155397 PRO-HD2 Degrader / Unkown
HY-172200A PD-L1/HDAC6-IN-1 TFA Inhibitor 99.55% Unkown
HY-178336 AC-340 Inhibitor / Unkown
HY-180224 HDAC6-IN-70 Inhibitor / Unkown
HY-149946 HDAC-IN-57 Inhibitor 99.61% Unkown
HY-151364 HDAC6/8/BRPF1-IN-1 Inhibitor / Unkown
HY-177759 PROTAC HDAC6 degrader 9 Degrader / Unkown
HY-161984 HDAC-IN-76 Inhibitor / Unkown
HY-161350 ALK/HDAC-IN-1 Inhibitor / Unkown
HY-180934 AMC-3-030 Inhibitor / Unkown
HY-176868 Rodin-C Inhibitor / Unkown
HY-162678 HDAC-IN-75 Inhibitor / Unkown
HY-161783 HDAC6-IN-45 Inhibitor / Unkown
HY-176561 IOR-160 Inhibitor / Unkown
HY-161524 HDAC6-IN-43 Inhibitor / Unkown
HY-173330 HDAC-IN-89 Inhibitor / Unkown
HY-184525 HDAC6-IN-85 Inhibitor 97.58% Unkown
HY-150577 HDAC-IN-45 Inhibitor / Unkown
HY-144449 mTOR/HDAC6-IN-1 Inhibitor / Unkown
HY-161155 HDAC6-IN-31 Inhibitor / Unkown
HY-143241 HDAC-IN-34 Inhibitor / Unkown
HY-174449 HDAC6-IN-62 Inhibitor / Unkown
HY-151263 G4/HDAC-IN-1 Inhibitor / Unkown
HY-146159 PI3K/HDAC-IN-2 Inhibitor / Unkown
HY-168508 PB200 Inhibitor / Unkown
HY-172873 HDSI-18 Inhibitor / Unkown
HY-147873 NMDAR/HDAC-IN-1 Inhibitor / Unkown
HY-146160 PARP-1/HDAC-IN-1 Inhibitor / Unkown
HY-178021 HDAC1-IN-11 Inhibitor / Unkown
HY-180829 HDAC6-IN-71 Inhibitor / Unkown
HY-169156 HDAC6-IN-49 Inhibitor / Unkown
HY-144782 HDAC10-IN-2 Inhibitor / Unkown
HY-183985 Hsp110/HDAC6-IN-1 Inhibitor / Unkown
HY-147731 HDAC6-IN-9 Inhibitor / Unkown
HY-158371 HDAC/CK2-IN-1 Inhibitor / Unkown
HY-181086 FLT3/HDAC-IN-3 Inhibitor / Unkown
HY-158308 HDAC6-IN-41 Inhibitor / Unkown
HY-151443 HDAC-IN-47 Inhibitor / Unkown
HY-143877 NN-390 Inhibitor / Unkown
HY-161667 GSK-3β/HDAC-IN-1 Inhibitor / Unkown
HY-168477 HDAC1-IN-8 Inhibitor / Unkown
HY-147966 HDAC-IN-43 Inhibitor / Unkown
HY-152146 HDAC-IN-50 Inhibitor / Unkown
HY-176733 HDAC6-IN-61 Inhibitor / Unkown
HY-184203 SM-06-09 Inhibitor / Unkown
HY-149029 TH-6 Inhibitor 96.64% Unkown
HY-149578 Tubulin/HDAC-IN-3 Inhibitor / Unkown
HY-144654 HDAC/Top-IN-1 Inhibitor / Unkown
HY-143324 A2AAR/HDAC-IN-1 Inhibitor / Unkown
HY-174302 PIM-1/HDAC-IN-2 Inhibitor / Unkown
HY-182720 FT108 Inhibitor / Unkown
HY-152235 HDAC6-IN-15 Inhibitor / Unkown
HY-162630 HDAC6-IN-44 Inhibitor / Unkown
HY-169405 AAK1/HDACs-IN-1 Inhibitor / Unkown
HY-144725 HDAC1/6-IN-1 Inhibitor / Unkown
HY-123699 NCT-10b Inhibitor / Unkown
HY-187387 PROTAC HDAC6/ERα degrader 1 Degrader / Unkown
HY-152133 PROTAC HDAC6 degrader 1 Degrader / Unkown
HY-15433B Quisinostat hydrochloride Inhibitor / Unkown
HY-161516 HDAC6-IN-42 Inhibitor / Unkown
HY-163359 CYP17A1/HDAC6-IN-1 Inhibitor / Unkown
HY-181942 HDAC6-IN-77 Inhibitor / Unkown
HY-180811 ALK/HDAC-IN-2 Inhibitor / Unkown
HY-173555 HDAC6-IN-54 Inhibitor / Unkown
HY-184430 HDAC6 ligand-8 Ligand / Unkown
HY-144292 HDAC-IN-30 Inhibitor / Unkown
HY-183320 HDAC6-IN-81 Inhibitor / Unkown
HY-119316A CM-545 Inhibitor / Unkown
HY-162319 Tubulin/HDAC-IN-4 Inhibitor / Unkown
HY-181639 HDAC6-IN-75 MDM2 Inhibitor 99.86% Unkown
HY-161854 LASSBio-1911 Inhibitor / Unkown
HY-161688 HDAC-IN-73 Inhibitor / Unkown
HY-146351 HDAC-IN-38 Inhibitor / Unkown
HY-184706 SHN7 Inhibitor / Unkown
HY-133147 HDAC3/6-IN-2 Inhibitor / Unkown
HY-178023 HDAC6-IN-64 Inhibitor / Unkown
HY-174471 HDAC-IN-90 Ligand / Unkown
HY-179272 Wee1/HDAC-IN-1 Inhibitor / Unkown
HY-178333 HDAC6-IN-66 Inhibitor / Unkown
HY-179019 HDAC-IN-94 Inhibitor / Unkown
HY-184505 (±)-trans-BAS-2 Inhibitor / Unkown
HY-183057 GRK2 modulator 1 Inhibitor / Unkown
HY-162955 LSD1/HDAC-IN-1 Inhibitor / Unkown
HY-139181 NR160 Inhibitor 98.9% Unkown
HY-123971 PROTAC HDAC6 degrader 12 Degrader / Unkown
HY-172129 HDAC6-IN-52 Inhibitor / Unkown
HY-184165 F2F-202 Inhibitor / Unkown
HY-150694 HDAC6-IN-11 Inhibitor / Unkown
HY-161778 ZG-126 Inhibitor / Unkown
HY-163503 HDAC6-IN-38 Inhibitor / Unkown
HY-12487 NL-103 Inhibitor / Unkown
HY-144297 HDAC1-IN-3 Inhibitor / Unkown
HY-152226 MC2590 Inhibitor 98.71% Unkown
HY-149283 JAK/HDAC-IN-2 Inhibitor / Unkown
HY-174265 HDAC6-IN-60 Inhibitor / Unkown
HY-162658 Leuxinostat Inhibitor / Unkown
HY-150597 HDAC-IN-46 Inhibitor / Unkown
HY-184979 HDAC6 ligand 10 Inhibitor / Unkown
HY-146750 HDAC-IN-37 Inhibitor / Unkown
HY-146539 HDAC-IN-35 Inhibitor / Unkown
HY-168650 ROCK/HDAC-IN-1 Inhibitor / Unkown
HY-174398 GSK-3β/HDAC-IN-2 Inhibitor / Unkown
HY-179227 HDAC6 ligand-7 Inhibitor / Unkown
HY-170379 HDAC-IN-84 Inhibitor / Unkown
HY-184415 Syk/HDAC6-IN-1 Inhibitor / Unkown
HY-184550 HDAC6 ligand-9 Ligand / Unkown
HY-157314 HDAC6-IN-27 Inhibitor / Unkown
HY-141541 MPT0G413 Inhibitor / Unkown
HY-182649 NN-429 Inhibitor / Unkown
HY-147892 HDAC-IN-42 Inhibitor / Unkown
HY-151897 HDAC-IN-49 Inhibitor / Unkown
HY-178022 HDAC6-IN-63 Inhibitor / Unkown
HY-19754 CRA-026440 Inhibitor / Unkown
HY-139815 ZYJ-34c Inhibitor / Unkown
HY-W555601 Nicoxamat Inhibitor 99.05% Unkown
HY-185359 HDAC6-IN-78 Inhibitor / Unkown
HY-139795 ZYJ-25e Inhibitor / Unkown
HY-160846 HDAC6-IN-40 Inhibitor / Unkown
HY-160845 HDAC6-IN-39 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HDAC6 NCBI NCBI:10013