HDAC1 - histone deacetylase 1 Gene

Also Known as HD1; RPD3; KDAC1; GON-10; RPD3L1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3065

About HDAC1

Cytogenetic location: 1p35.2-p35.1 Genomic coordinates (GRCh38): 1:32,292,083-32,333,626 (from NCBI)

This gene has 10 transcripts (splice variants), 254 orthologues and 10 paralogues. Ubiquitous expression in lymph node (RPKM 56.9), colon (RPKM 56.3) and 25 other tissues.

Summary

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and Apoptosis. [provided by RefSeq, Jul 2008]

HDAC1 Products (2)

mRNA Protein Name
NM_004964.3 NP_004955.2 histone deacetylase 1
XM_011541309.3 XP_011539611.1 histone deacetylase 1 isoform X1

HDAC1 Protein Structure

Hist_deacetyl

Hist_deacetyl: Histone deacetylase domain (25 - 318)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 482 a.a.
Protein Preferred Names Protein Names

histone deacetylase 1

  • protein deacetylase HDAC1

  • protein decrotonylase HDAC1

  • reduced potassium dependency, yeast homolog-like 1

HDAC1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
HDAC1 Q13547 ARID5B Homo sapiens Q14865 33961781
Intra
HDAC1 Q13547 ARID5B Homo sapiens Q14865 26496610
Intra
HDAC1 Q13547 ARID5B Homo sapiens Q14865 28514442
Intra
HDAC1 Q13547 ARID5B Homo sapiens Q14865 23752268
Intra
HDAC1 Q13547 ARID5B Homo sapiens Q14865 35271311
Intra
HDAC1 Q13547 ARID5B Homo sapiens Q14865 23752268
Intra
HDAC1 Q13547 ARID5B Homo sapiens Q14865 23752268
Intra
HDAC1 Q13547 E4F1 Homo sapiens Q66K89 12730668
Intra
HDAC1 Q13547 E4F1 Homo sapiens Q66K89 12730668
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776 33961781
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776 26949739
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776 21258344
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776 17956988
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776 28514442
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776
GMS
19703393
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776 23752268
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776 35271311
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776 20127688
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776 20127688
Intra
HDAC1 Q13547 MTA2 Homo sapiens O94776 26496610
Intra
HDAC1 Q13547 MBD3 Homo sapiens O95983 23752268
Intra
HDAC1 Q13547 MBD3 Homo sapiens O95983 21258344
Intra
HDAC1 Q13547 MBD3 Homo sapiens O95983 33961781
Intra
HDAC1 Q13547 MBD3 Homo sapiens O95983 26496610
Intra
HDAC1 Q13547 MBD3 Homo sapiens O95983 35271311
Intra
HDAC1 Q13547 ZBTB7A Homo sapiens O95365 24514149
Intra
HDAC1 Q13547 ZNF516 Homo sapiens Q92618 23752268
Intra
HDAC1 Q13547 ZNF516 Homo sapiens Q92618 33961781
Intra
HDAC1 Q13547 ZNF516 Homo sapiens Q92618 28514442
Intra
HDAC1 Q13547 ZNF516 Homo sapiens Q92618 35271311
Intra
HDAC1 Q13547 SP1 Homo sapiens P08047 12847090
Intra
HDAC1 Q13547 SP1 Homo sapiens P08047 18003922
Intra
HDAC1 Q13547 NFKB1 Homo sapiens P19838 11931769
Intra
HDAC1 Q13547 NFKB1 Homo sapiens P19838 11931769
Intra
HDAC1 Q13547 NFKB1 Homo sapiens P19838
PLA
25241761
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769 22416134
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769 17956988
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769 35271311
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769 11739383
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769 26496610
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769
TAP
24981860
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769 23752268
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769 21258344
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769 33961781
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769
GMS
19703393
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769
PLA
25241761
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769 26949739
Intra
HDAC1 Q13547 HDAC2 Homo sapiens Q92769 28514442
Intra
HDAC1 Q13547 H4C16 Homo sapiens P62805 26496610
Intra
HDAC1 Q13547 H4C16 Homo sapiens P62805 10220385
Intra
HDAC1 Q13547 SIN3A Homo sapiens Q96ST3 33961781
Intra
HDAC1 Q13547 SIN3A Homo sapiens Q96ST3 28514442
Intra
HDAC1 Q13547 SIN3A Homo sapiens Q96ST3 23752268
Intra
HDAC1 Q13547 SIN3A Homo sapiens Q96ST3 21258344
Intra
HDAC1 Q13547 SIN3A Homo sapiens Q96ST3 26949739
Intra
HDAC1 Q13547 SIN3A Homo sapiens Q96ST3 10220385
Intra
HDAC1 Q13547 SIN3A Homo sapiens Q96ST3 26496610
Intra
HDAC1 Q13547 SIN3A Homo sapiens Q96ST3 35271311
Intra
HDAC1 Q13547 SIN3A Homo sapiens Q96ST3 17956988
Intra
HDAC1 Q13547 CSNK2A1 Homo sapiens P68400 35271311
Intra
HDAC1 Q13547 CSNK2A1 Homo sapiens P68400 23752268
Intra
HDAC1 Q13547 SUV39H1 Homo sapiens O43463 12711603
Intra
HDAC1 Q13547 MIER1 Homo sapiens Q8N108 35271311
Intra
HDAC1 Q13547 MIER1 Homo sapiens Q8N108 12482978
Intra
HDAC1 Q13547 MIER1 Homo sapiens Q8N108 23752268
Intra
HDAC1 Q13547 MIER1 Homo sapiens Q8N108 12482978
Intra
HDAC1 Q13547 MIER1 Homo sapiens Q8N108 33961781
Intra
HDAC1 Q13547 MIER1 Homo sapiens Q8N108 28514442
Intra
HDAC1 Q13547 MIER1 Homo sapiens Q8N108 21258344
Intra
HDAC1 Q13547 DDX5 Homo sapiens P17844 15298701
Intra
HDAC1 Q13547 RBBP7 Homo sapiens Q16576 35271311
Intra
HDAC1 Q13547 RBBP7 Homo sapiens Q16576 9150135
Intra
HDAC1 Q13547 RBBP7 Homo sapiens Q16576
GMS
19703393
Intra
HDAC1 Q13547 RBBP7 Homo sapiens Q16576 23752268
Intra
HDAC1 Q13547 RBBP7 Homo sapiens Q16576 33961781
Intra
HDAC1 Q13547 RBBP7 Homo sapiens Q16576 26496610
Intra
HDAC1 Q13547 RBBP7 Homo sapiens Q16576 21258344
Intra
HDAC1 Q13547 TP53 Homo sapiens P04637 20075864
Intra
HDAC1 Q13547 CHD4 Homo sapiens Q14839 21258344
Intra
HDAC1 Q13547 CHD4 Homo sapiens Q14839 33961781
Intra
HDAC1 Q13547 CHD4 Homo sapiens Q14839 10220385
Intra
HDAC1 Q13547 CHD4 Homo sapiens Q14839 35271311
Intra
HDAC1 Q13547 CHD4 Homo sapiens Q14839 26949739
Intra
HDAC1 Q13547 CHD4 Homo sapiens Q14839 23752268
Intra
HDAC1 Q13547 E2F1 Homo sapiens Q01094 9468140
Intra
HDAC1 Q13547 E2F1 Homo sapiens Q01094 9468139
Intra
HDAC1 Q13547 RB1 Homo sapiens P06400 29997244
Intra
HDAC1 Q13547 RB1 Homo sapiens P06400 22366686
Intra
HDAC1 Q13547 RB1 Homo sapiens P06400 23752268
Intra
HDAC1 Q13547 HDAC3 Homo sapiens O15379 22918830
Intra
HDAC1 Q13547 HDAC3 Homo sapiens O15379 22918830
Intra
HDAC1 Q13547 RBBP4 Homo sapiens Q09028 21258344
Intra
HDAC1 Q13547 RBBP4 Homo sapiens Q09028 33961781
Intra
HDAC1 Q13547 RBBP4 Homo sapiens Q09028
GMS
19703393
Intra
HDAC1 Q13547 RBBP4 Homo sapiens Q09028 35271311
Intra
HDAC1 Q13547 RBBP4 Homo sapiens Q09028 20127688
Intra
HDAC1 Q13547 RBBP4 Homo sapiens Q09028 10220385
Intra
HDAC1 Q13547 RBBP4 Homo sapiens Q09028 23752268
Intra
HDAC1 Q13547 RBBP4 Homo sapiens Q09028
TAP
24981860
Intra
HDAC1 Q13547 BCL11B Homo sapiens Q9C0K0
IF
17245431
Intra
HDAC1 Q13547 BCL11B Homo sapiens Q9C0K0 23752268
Intra
HDAC1 Q13547 BCL11B Homo sapiens Q9C0K0 17245431
Intra
HDAC1 Q13547 PWWP2A Homo sapiens Q96N64 33961781
Intra
HDAC1 Q13547 PWWP2A Homo sapiens Q96N64 23752268
Intra
HDAC1 Q13547 PWWP2A Homo sapiens Q96N64 23752268
Intra
HDAC1 Q13547 PWWP2A Homo sapiens Q96N64 26496610
Intra
HDAC1 Q13547 PWWP2A Homo sapiens Q96N64 35271311
Intra
HDAC1 Q13547 C16orf87 Homo sapiens Q6PH81 33961781
Intra
HDAC1 Q13547 C16orf87 Homo sapiens Q6PH81 35271311
Intra
HDAC1 Q13547 C16orf87 Homo sapiens Q6PH81 23752268
Intra
HDAC1 Q13547 ZBTB16 Homo sapiens Q05516 37398436
Intra
HDAC1 Q13547 ZBTB16 Homo sapiens Q05516 32814053
Intra
HDAC1 Q13547 ZBTB16 Homo sapiens Q05516 29997244
Intra
HDAC1 Q13547 MTA1 Homo sapiens Q13330 35271311
Intra
HDAC1 Q13547 MTA1 Homo sapiens Q13330 23752268
Intra
HDAC1 Q13547 MTA1 Homo sapiens Q13330 26028330
Intra
HDAC1 Q13547 MTA1 Homo sapiens Q13330 33961781
Intra
HDAC1 Q13547 MTA1 Homo sapiens Q13330 26496610
Intra
HDAC1 Q13547 MTA1 Homo sapiens Q13330 26949739
Intra
HDAC1 Q13547 MTA1 Homo sapiens Q13330 21258344
Intra
HDAC1 Q13547 BRMS1 Homo sapiens Q9HCU9 33961781
Intra
HDAC1 Q13547 BRMS1 Homo sapiens Q9HCU9 16919237
Intra
HDAC1 Q13547 BRMS1 Homo sapiens Q9HCU9 23752268
Intra
HDAC1 Q13547 BRMS1 Homo sapiens Q9HCU9 21258344
Intra
HDAC1 Q13547 RELA Homo sapiens Q04206 11931769
Intra
HDAC1 Q13547 RELA Homo sapiens Q04206 11931769
Intra
HDAC1 Q13547 MAGEA1 Homo sapiens P43355 15316101
Intra
HDAC1 Q13547 MAGEA1 Homo sapiens P43355 15316101
Intra
HDAC1 Q13547 SINHCAF Homo sapiens Q9NP50 23752268
Intra
HDAC1 Q13547 SINHCAF Homo sapiens Q9NP50 23752268
Intra
HDAC1 Q13547 SINHCAF Homo sapiens Q9NP50 26496610
Intra
HDAC1 Q13547 SINHCAF Homo sapiens Q9NP50 33961781
Intra
HDAC1 Q13547 SINHCAF Homo sapiens Q9NP50 23752268
Intra
HDAC1 Q13547 SINHCAF Homo sapiens Q9NP50 35271311
Intra
HDAC1 Q13547 EHMT2 Homo sapiens Q96KQ7 33961781
Intra
HDAC1 Q13547 EHMT2 Homo sapiens Q96KQ7 23752268
Intra
HDAC1 Q13547 EHMT2 Homo sapiens Q96KQ7 16287849
Intra
HDAC1 Q13547 DAXX Homo sapiens Q9UER7 12529400
Intra
HDAC1 Q13547 NCOR2 Homo sapiens Q9Y618 11739383
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0 28514442
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0 17939992
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0 17939992
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0 23752268
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0 35271311
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0
GMS
19497860
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0 21258344
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0
GMS
19703393
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0 17956988
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0 33961781
Intra
HDAC1 Q13547 RCOR1 Homo sapiens Q9UKL0 26496610
Intra
HDAC1 Q13547 GFI1 Homo sapiens Q99684 16287849
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant HDAC1 Proteins

Cat. No. Product Name Accession Purity
HY-P72262 Histone deacetylase 1/HDAC1 Protein, Human (His-SUMO) Q13547 (M1-A482) ≥ 90%, as determined by reducing SDS-PAGE.

HDAC1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P80149 HDAC1 Antibody (YA395) WB, IHC-P, ICC/IF Human, Mouse
HY-P84550 HDAC1 Antibody (YA4247) WB, IHC-P, FC, ELISA Human, Mouse, Rat
HY-P84550A HDAC1 Antibody (YA4247)(PBS only) WB, IHC-P, FC, ELISA Human, Mouse, Rat
HY-P85878 HDAC1 Antibody (YA5570) WB, ICC/IF, ELISA Human, Mouse, Rat
HY-P86491 HDAC1 Antibody (YA6183) WB, IHC-P, ICC/IF, ELISA Human, Mouse, Rat

Related Diseases

Diseases Alias
Asthma
  • Chronic Obstructive Asthma

  • Asthma, Diminished Response To Antileukotriene Treatment In

  • Bronchial Hyperreactivity

  • Asthma, Susceptibility To

  • Asthma, Bronchial

  • Asthma, Protection Against

  • Asthma, Nocturnal, Susceptibility To

  • Nocturnal Asthma

  • Asthma-Related Traits

  • Asthma-Related Traits, Susceptibility To

  • Asthma, Nocturnal

  • Chronic Obstructive Asthma With Acute Exacerbation

  • Chronic Obstructive Asthma With Status Asthmaticus

  • Exercise Induced Asthma

  • Exercise-Induced Asthma

  • Bronchial Asthma

  • Asthma, Exercise-Induced

  • Idiosyncratic Asthma

  • Unspecified Asthma With Acute Exacerbation

  • Asthma, Unspecified, With Stated Status Asthmaticus

  • Status Asthmaticus Nos

  • Acute Severe Asthma

  • Acute Severe Bronchial Asthma

  • Status Asthma

  • Status Post Asthmaticus

Cockayne Syndrome
  • Cockayne'S Syndrome

  • Dwarfism-Retinal Atrophy-Deafness Syndrome

  • Neill-Dingwall Syndrome

  • Progeria-Like Syndrome

  • Progeroid Nanism

  • Cs

Ovarian Cancer
  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Cancer Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary

Pancreatic Cancer
  • Pancreatic Carcinoma

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Carcinoma Of Pancreas

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Cancer Of The Pancreas

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Mature T-Cell And Nk-Cell Lymphoma
  • Mature T-Cell And Natural Killer Cell Lymphoma

  • Nk-T Cell Lymphoma

Colorectal Cancer
  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon

Ataxia-Telangiectasia
  • Ataxia Telangiectasia

  • Louis-Bar Syndrome

  • AT

  • At1

  • Ataxia-Telangiectasia Syndrome

  • Ataxia - Telangiectasia Variant

  • Boder-Sedgwick Syndrome

  • Louis Bar Syndrome

  • Cerebello-Oculocutaneous Telangiectasia

  • Immunodeficiency With Ataxia Telangiectasia

  • A-T

  • Ataxia Telangiectasia Syndrome

  • Atm

  • Telangiectasia, Cerebello-Oculocutaneous

  • Ataxia-Telangiectasia Variant

Hutchinson-Gilford Progeria Syndrome
  • Progeria

  • HGPS

  • Hutchinson-Gilford Syndrome

  • Hutchinson-Gilford Progeria

  • Hutchinson Gilford Syndrome

  • Hutchinson-Gilford Disease

  • Hutchinson Gilford Progeria Syndrome

  • Progeria Of Childhood

  • Hutchinson-Gilford-Progeria Syndrome

Rhabdomyosarcoma
Peripheral T-Cell Lymphoma
  • Lymphoma T-Cell Peripheral

Eye Disease
  • Eye Diseases

  • Abnormality Of The Eye

  • Toxoplasma Oculopathy

Neuroblastoma
  • Nb

  • Neuroblastoma, Susceptibility To

  • Neuroblastomas

  • Central Neuroblastoma

Primary Hyperoxaluria
  • Hyperoxaluria, Primary

  • Oxalosis

  • Hyperoxaluria

  • Primary Oxalosis

  • Congenital Oxaluria

  • D-Glycerate Dehydrogenase Deficiency

  • Glyceric Aciduria

  • Glycolic Aciduria

  • Hepatic Agt Deficiency

  • Oxaluria, Primary

  • Peroxisomal Alanine:Glyoxylate Aminotransferase Deficiency

  • Primary Oxaluria

  • Hyperoxaluria Primary

  • Primary Hyperoxaluria Type 2

  • Primary Hyperoxaluria, Type I

Optic Atrophy 10 With Or Without Ataxia, Mental Retardation, And Seizures
  • OPA10

  • Optic Atrophy 10 With Or Without Ataxia, Intellectual Disability, And Seizures

  • Optic Atrophy 10

  • Atrophy, Optic, Type 10, With/Without Ataxia, Mental Retardation, And Seizures

Gastric Cancer
  • Stomach Cancer

  • Stomach Carcinoma

  • Gastric Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach

Holoprosencephaly
  • Holoprosencephaly Sequence

  • Hpe

  • Hpe - [Holoprosencephaly]

Rett Syndrome
  • Atypical Rett Syndrome

  • RTT

  • Rts

  • Autism, Dementia, Ataxia, And Loss Of Purposeful Hand Use

  • Rett Syndrome, Atypical

  • Rett Syndrome, Preserved Speech Variant

  • Rett'S Disorder

  • Rett Syndrome Variant

  • Rett Disorder

  • Cerebroatrophic Hyperammonemia

  • Rett Like Syndrome

  • Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use Syndrome

  • Rett'S Syndrome

  • Atypical Rtt

  • Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use

  • Rett Syndrome Preserved Speech Variant

  • Rett Syndrome Zappella Variant

  • Rett Syndrome, Zappella Variant

B-Cell Lymphoma
  • Lymphoma, B-Cell

  • B-Cell Lymphomas

  • B-Cell Lymphocytic Neoplasm

  • Lymphoma B-Cell

  • B-Cell Lymphoma Nos

Acute Promyelocytic Leukemia
  • Leukemia, Acute Promyelocytic

  • Acute Myeloblastic Leukemia Type 3

  • Aml M3

  • APL

  • Leukemia, Acute Promyelocytic, Somatic

  • Aml With T(15

  • 17)(Q22

  • Q12)

  • (Pml/Raralpha) And Variants

  • Apml

  • Acute Myeloblastic Leukemia 3

  • Acute Myeloid Leukemia With T(15

  • 17)(Q22

  • Q12)

  • (Pml/Raralpha) And Variants

  • Acute Myeloblastic Leukaemia Type 3

  • Acute Myeloid Leukaemia M3

  • Acute Myeloid Leukemia M3

  • Acute Promyelocytic Leukaemia

  • M3 Anll

  • Myeloid Leukemia, Acute, M3

  • Leukemia Promyelocytic Acute

  • Leukemia, Promyelocytic, Acute

  • Leukemia, Acute, Promyelocytic

Retinoblastoma
  • RB

  • Trilateral Retinoblastoma

  • RB1

  • Retinoblastoma, Trilateral

  • Neuroblastoma Of Retina

  • Rb - Retinoblastoma

  • Eye Cancer, Retinoblastoma

  • Retinal Cancer

  • Retinal Tumor

  • Glioma, Retinal

  • Non-Hereditary Retinoblastoma

  • Childhood Cancer Retinoblastoma

  • Malignant Neoplasm Of Retina

  • Retinal Neoplasms

Lung Cancer
  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Protection Against

  • Lung Cancer, Susceptibility To

  • Adenocarcinoma Of Lung, Somatic

  • Nonsmall Cell Lung Cancer

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma

Breast Cancer
  • Breast Carcinoma

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Male Breast Cancer

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation

Leukemia, Acute Myeloid
  • Acute Myeloid Leukemia

  • Leukemia, Acute Myelogenous

  • Acute Myelogenous Leukemia

  • AML

  • Leukemia, Acute Myeloid, Susceptibility To

  • Acute Myeloblastic Leukemia

  • Leukemia, Acute Myeloid, Reduced Survival In, Somatic

  • Acute Myeloid Leukaemia

  • Leukemia, Myelocytic, Acute

  • Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

  • Secondary Aml

  • Acute Myelocytic Leukemia

  • Leukemia, Myeloid, Acute

  • Acute Myeloid Leukemia, Somatic

  • Leukemia, Acute Myeloid, Somatic

  • Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

  • Acute Myeloblastic Leukaemia

  • Acute Myelogenous Leukaemia

  • Aml - Acute Myeloid Leukemia

  • Acute Myeloid Leukemia With Cebpa Somatic Mutations

  • Aml With Cebpa Somatic Mutations

  • Inherited Acute Myeloid Leukemia

  • Familial Aml

  • Inherited Aml

  • Pure Familial Aml

  • Pure Familial Acute Myeloid Leukemia

  • Secondary Acute Myeloid Leukemia

  • Therapy-Related Aml And Myelodysplastic Syndrome

  • Acute Myeloid Leukemia, Secondary

  • Acute Non-Lymphoblastic Leukemia

  • Acute Non-Lymphocytic Leukemia

  • Acute Biphenotypic Leukemia

  • Acute Undifferentiated Leukemia

  • Acute Myeloblastic Leukaemia With Multilineage Dysplasia

  • Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

  • Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Esophageal Cancer
  • Esophageal Carcinoma

  • Carcinoma Of Esophagus

  • Esophageal Squamous Cell Carcinoma, Somatic

  • Esophageal Carcinoma, Somatic

  • Esophagus Cancer

  • Gastric Cardia Adenocarcinoma

  • Esophageal Neoplasms

  • Esophageal Cancer, Somatic

  • Cancer Of Esophagus

  • Cancer Of Oesophagus

  • Carcinoma Of Oesophagus

  • Ca Lower Third Oesophagus

  • Ca Middle Third Oesophagus

  • Malignant Neoplasm Of Distal Third Of Esophagus

  • Malignant Neoplasm Of Lower Third Of Oesophagus

  • Malignant Neoplasm Of Middle Third Of Oesophagus

  • Malignant Neoplasm Of Proximal Third Of Esophagus

  • Malignant Neoplasm Of Upper Third Esophagus

  • Malignant Tumor Of Abdominal Esophagus

  • Malignant Tumor Of Distal Third Of Esophagus

  • Malignant Tumor Of Proximal Third Of Esophagus

  • Malignant Tumor Of The Middle Third Of The Esophagus

  • ESCR

  • Aerodigestive Tract Cancer

  • Escc

  • Esophageal Squamous Cell Carcinoma

  • Cancer, Esophageal

  • Malignant Neoplasm Of Esophagus

  • Squamous Cell Carcinoma Of Esophagus

  • Malignant Neoplasm Of Middle Third Of Esophagus

Chromosome 16p13.3 Deletion Syndrome, Proximal
  • Rubinstein-Taybi Syndrome

  • Broad Thumb-Hallux Syndrome

  • Chromosome 16p13.3 Deletion Syndrome

  • Rubinstein-Taybi Syndrome Due To 16p13.3 Microdeletion

  • Rubinstein Syndrome

  • Broad Thumbs-Halluces Syndrome

  • Rsts

  • Rubinstein-Taybi Deletion Syndrome

  • Rsts Deletion Syndrome

  • Proximal Chromosome 16p13.3 Deletion Syndrome

  • 16p13.3 Deletion Syndrome

  • Broad Thumbs And Great Toes, Characteristic Facies, And Mental Retardation

  • Rts

Peripheral Nervous System Disease
  • Peripheral Neuropathy

  • Peripheral Nerve Disease

  • Peripheral Nerve Disorders

  • Neuropathy, Peripheral

  • Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation

Endobronchial Lipoma
Nervous System Disease
  • Abnormality Of The Nervous System

  • Nervous System Diseases

  • Nervous System Disorder

Huntington Disease
  • Huntington'S Disease

  • Huntington Chorea

  • HD

  • Huntington'S Chorea

  • Huntington Chronic Progressive Hereditary Chorea

  • Juvenile Huntington Disease

  • Chronic Progressive Chorea

  • Chronic Progressive Hereditary Chorea

  • Hc - [Huntington Chorea]

  • Hereditary Chorea

  • Progressive Hereditary Chorea

Hyperoxaluria, Primary, Type I
  • Primary Hyperoxaluria Type 1

  • HP1

  • Glycolic Aciduria

  • Alanine-Glyoxylate Aminotransferase Deficiency

  • Hepatic Agt Deficiency

  • Oxalosis I

  • Primary Hyperoxaluria, Type I

  • Serine:Pyruvate Aminotransferase Deficiency

  • Hyperoxaluria, Primary, Type 1

  • Peroxisomal Alanine-Glyoxylate Aminotransferase Deficiency

  • Peroxisomal Alanine Glyoxylate Aminotransferase Deficiency

  • Serine Pyruvate Aminotransferase Deficiency

  • Peroxisomal Alanine:Glyoxylate Aminotransferase Deficiency

  • Oxalosis 1

  • Hyperoxaluria Primary 1

  • Hyperoxaluria Primary Type I

  • Ph1

  • Primary Hyperoxaluria Type I

  • Oxalosis Type 1

  • 2-Oxoglutarate Glyoxylate Carboligase Deficiency

Medulloblastoma
  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Desmoplastic/Nodular Medulloblastoma

  • Medulloblastoma With Extensive Nodularity

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, Somatic

  • Medulloblastoma, Desmoplastic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Mben

  • Medulloblastoma Desmoplastic

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site

Prostate Cancer
  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HDAC1 RGD RGD:1309799
Felis catus HDAC1 VGNC VGNC:67548
Macaca mulatta HDAC1 VGNC VGNC:99966
Bos taurus HDAC1 VGNC VGNC:49065
Mus musculus HDAC1 MGD MGI:108086
Canis familiaris HDAC1 VGNC VGNC:50625
Others HDAC1 NCBI