ACHE - acetylcholinesterase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83817

About ACHE

Primary_assembly 12: 19,407,360-19,413,651 reverse strand.mRatBN7.2:CM026985.1

This gene has 2 transcripts (splice variants), 234 orthologues, 27 paralogues and is associated with 38 phenotypes. Biased expression in Muscle (RPKM 131.4), Brain (RPKM 122.4) and 7 other tissues.

Summary

Enables acetylcholine binding activity; acetylcholinesterase activity; and choline binding activity. Involved in several processes, including acetylcholine catabolic process; positive regulation of neurogenesis; and response to Insulin. Located in several cellular components, including endoplasmic reticulum; neuronal cell body; and synaptic membrane. Is active in neuromuscular junction and synaptic cleft. Biomarker of acute stress disorder and leptospirosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; epilepsy; and myasthenia gravis. Orthologous to human AChE (acetylcholinesterase (Cartwright blood group)). [provided by Alliance of Genome Resources, Apr 2022]

ACHE Products (1)

mRNA Protein Name
NM_172009.2 NP_742006.2 acetylcholinesterase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetylcholine binding IDA
IDA: Inferred from direct assay
126256 RGD
enables acetylcholinesterase activity IDA
IDA: Inferred from direct assay
126256 RGD
enables choline binding IDA
IDA: Inferred from direct assay
1133098 RGD
Biological Process GO Annotation Evidence References Source
involved in acetylcholine catabolic process IDA
IDA: Inferred from direct assay
126256 RGD
involved in acetylcholine metabolic process IMP
IMP: Inferred from mutant phenotype
16628397 RGD
involved in brain development IEP
IEP: Inferred from expression pattern
20147288 RGD
involved in choline metabolic process IDA
IDA: Inferred from direct assay
1133098 RGD
involved in choline metabolic process IMP
IMP: Inferred from mutant phenotype
16628397 RGD
involved in positive regulation of axonogenesis IMP
IMP: Inferred from mutant phenotype
12799140 RGD
involved in positive regulation of dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
12799140 RGD
involved in response to cadmium ion IEP
IEP: Inferred from expression pattern
27491636 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
8293290 RGD
involved in response to insecticide IEP
IEP: Inferred from expression pattern
7537966 RGD
involved in response to insulin IDA
IDA: Inferred from direct assay
19347982 RGD
involved in response to nicotine IEP
IEP: Inferred from expression pattern
20309727 RGD
involved in synapse assembly IMP
IMP: Inferred from mutant phenotype
12799140 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
1133098 RGD
located in cell surface IDA
IDA: Inferred from direct assay
2731551 RGD
located in dendrite IDA
IDA: Inferred from direct assay
1133098 RGD
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
1133098 RGD
located in membrane raft IDA
IDA: Inferred from direct assay
20147288 RGD
is active in neuromuscular junction IDA
IDA: Inferred from direct assay
26820598 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
1133098 RGD
located in nuclear envelope IDA
IDA: Inferred from direct assay
1133098 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
16052514 RGD
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
3655326 RGD
located in presynaptic membrane IDA
IDA: Inferred from direct assay
3655326 RGD
is active in synaptic cleft IDA
IDA: Inferred from direct assay
26820598 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ACHE Protein Structure

COesterase

COesterase: pfam00135 (36 - 562)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 616 a.a.
Protein Preferred Names Protein Names

acetylcholinesterase

  • glycolipid-anchored form of acetylcholinesterase

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (26)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0034 Donepezil Hydrochloride Inhibitor 99.92% Yes
HY-14566 Donepezil Inhibitor 99.87% Yes
HY-17368 Rivastigmine Inhibitor 99.95% Yes
HY-76299 Galanthamine Inhibitor 99.90% Yes
HY-11017 Rivastigmine tartrate Inhibitor 99.03% Yes
HY-B0207A Pyridostigmine bromide Inhibitor 98.86% Yes
HY-17387 (-)-Huperzine A Inhibitor 99.95% Yes
HY-B1488 Tacrine hydrochloride Inhibitor 99.90% Unkown
HY-107922 Ethopropazine hydrochloride Inhibitor 99.32% Unkown
HY-B1266 Physostigmine salicylate Inhibitor 99.74% Unkown
HY-111338 Tacrine Inhibitor 99.10% Yes
HY-B0364A Dyclonine hydrochloride Inhibitor 99.12% Unkown
HY-A0009 Galanthamine hydrobromide Inhibitor 99.93% Yes
HY-B0884A Minaprine dihydrochloride Inhibitor 99.90% Unkown
HY-B1200 Pralidoxime chloride Activator 99.98% Unkown
HY-B0732 Itopride hydrochloride Inhibitor 99.84% Unkown
HY-B0882 Edrophonium chloride Inhibitor 98.68% Unkown
HY-100919 Ambenonium chloride Inhibitor 96.18% Yes
HY-B1738A Pralidoxime iodide Activator 98.0% Unkown
HY-B2244 Tacrine hydrochloride hydrate Inhibitor 99.98% Unkown
HY-B2155 Acotiamide monohydrochloride trihydrate Inhibitor 99.79% Yes
HY-B1738 Pralidoxime Activator ≥90.0% Unkown
HY-B0884 Minaprine Inhibitor / Unkown
HY-114899 Azamethiphos Inhibitor 98.10% Unkown
HY-B0732A Itopride Antagonist / Unkown
HY-B0949A Protriptyline Inhibitor / Unkown

Clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Phase
HY-103374 Phenserine Inhibitor 99.55% Phase 3
HY-B0916 Propoxur Inhibitor 99.43% Phase 3
HY-19651 Zanapezil free base Inhibitor 99.23% Phase 3
HY-127165 Velnacrine Inhibitor 98.79% Phase 3
HY-114422 p38α-IN-13 Inhibitor / Phase 3
HY-105157A Icopezil maleate Inhibitor / Phase 2
HY-135427 Quilostigmine Inhibitor / Phase 2
HY-106412A Stacofylline hydrochloride Inhibitor / Phase 2
HY-106440 Zifrosilone Inhibitor / Phase 2
HY-117710B AD-35 Inhibitor / Phase 2
HY-180141 AF03 Activator / Phase 1
HY-108048 Desoxypeganine Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (397)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108477 TMPyP4 tosylate Inhibitor 98.0% Unkown
HY-N0285 Imperatorin Inhibitor 98.59% Unkown
HY-107569 Garcinol Inhibitor 98.85% Unkown
HY-138097 α-NETA Inhibitor ≥98.0% Unkown
HY-B0815 Chlorpyrifos Inhibitor 99.94% Unkown
HY-N0528 Linarin Inhibitor 98.02% Unkown
HY-N0342 Scopoletin Inhibitor 99.89% Unkown
HY-N0226A Epiberberine chloride Inhibitor 98.68% Unkown
HY-N0286 Isoimperatorin Inhibitor 99.78% Unkown
HY-N5077 Sinapine Inhibitor 99.94% Unkown
HY-N0826 Corynoline Inhibitor 98.84% Unkown
HY-N0825 Nodakenin Inhibitor 98.70% Unkown
HY-N0810 Timosaponin AIII 99.86% Unkown
HY-N0923 Corydaline Inhibitor 99.70% Unkown
HY-W017423 (-)-Carvone Inhibitor 99.91% Unkown
HY-N0740 Jatrorrhizine chloride Inhibitor 99.82% Unkown
HY-75247 Coumaran Inhibitor 99.67% Unkown
HY-N4142 Cyanidin-3-O-galactoside chloride Inhibitor 99.20% Unkown
HY-Y0504 Trimethylammonium chloride Inhibitor 98.0% Unkown
HY-N0450 Sinapine thiocyanate Inhibitor 99.85% Unkown
HY-W159754 Chavicol Inhibitor 97.99% Unkown
HY-21629 N-Boc-4-piperidinemethanol 99.91% Unkown
HY-N2320 Physostigmine hemisulfate Inhibitor 99.80% Unkown
HY-N2230 N-p-trans-Coumaroyltyramine Inhibitor 99.28% Unkown
HY-N0631 Cornuside Inhibitor 99.99% Unkown
HY-N2081 Skimmianine Inhibitor 99.93% Unkown
HY-106901A Asoxime dichloride Inhibitor 98.47% Unkown
HY-Y0504S3 Trimethylammonium chloride-d9 Inhibitor 99.65% Unkown
HY-B0841 Acephate Inhibitor 98.0% Unkown
HY-B0832 Profenofos Inhibitor 96.07% Unkown
HY-N0859 Schisanhenol Inhibitor 99.99% Unkown
HY-N1474 Picfeltarraenin IA Inhibitor 99.85% Unkown
HY-N0702 Tenuifolin Inhibitor 99.73% Unkown
HY-N4225 Aaptamine Inhibitor 99.71% Unkown
HY-N0241 Rhodionin Inhibitor 99.73% Unkown
HY-122140 ACG548B Inhibitor 99.72% Unkown
HY-W130025 p-Xylene bispyridinium bromide Inhibitor 99.60% Unkown
HY-N6895 Violanthin Inhibitor 98.27% Unkown
HY-135761 Penconazole Inhibitor 98.91% Unkown
HY-100620 RPR121056 Inhibitor 99.88% Unkown
HY-N2425 Rhodiosin Inhibitor 99.07% Unkown
HY-B2015 Carbosulfan Inhibitor 98.0% Unkown
HY-NP192 Sericin Antagonist 0% Unkown
HY-17388 (±)-Huperzine A Inhibitor 98.73% Unkown
HY-N0749A Jatrorrhizine hydroxide Inhibitor 98.06% Unkown
HY-N4119 Neoeriocitrin Inhibitor 99.97% Unkown
HY-B1881 Pirimiphos-methyl Inhibitor 98.39% Unkown
HY-I0020 Galanthaminone Inhibitor 99.85% Unkown
HY-124957 β-NETA Inhibitor 98.0% Unkown
HY-N2511 Trimyristin Modulator 99.72% Unkown
HY-118165 Phenthoate Inhibitor 98.71% Unkown
HY-N2157 Pteryxin Inhibitor 99.55% Unkown
HY-N3270 Methyl orsellinate Inhibitor 99.91% Unkown
HY-34408 6-Methoxy-1-tetralone 99.89% Unkown
HY-122203 PCS1055 dihydrochloride Inhibitor 98.88% Unkown
HY-W014700 Glycyl-L-glutamic acid Modulator 99.89% Unkown
HY-N7612 N-Desmethyl Galanthamine Inhibitor 99.60% Unkown
HY-N7993 Manghaslin Inhibitor 98.76% Unkown
HY-P2616A Mca-YVADAP-Lys(Dnp)-OH TFA Chemical 98.29% Unkown
HY-W016188 1-Naphthyl acetate 99.89% Unkown
HY-N0801 Polygalacic acid Inhibitor 98.92% Unkown
HY-B0835 Fenobucarb Inhibitor 98.62% Unkown
HY-W017765 1,1'-Bi-2-naphthol Inhibitor 99.94% Unkown
HY-P4279 Ovalbumin (154-159) 99.18% Unkown
HY-W130236 Methylene Violet 3RAX Inhibitor 95.54% Unkown
HY-N2211 Picfeltarraenin IB Inhibitor 98.53% Unkown
HY-B0830 Isoprocarb Inhibitor 99.12% Unkown
HY-W278867 trans-3,5-Dimethoxystilbene Inhibitor 98.45% Unkown
HY-B1093 Fenchlorphos Inhibitor 99.95% Unkown
HY-10399A Ladostigil hydrochloride Inhibitor 99.91% Unkown
HY-119419 Pirimicarb Inhibitor 99.50% Unkown
HY-N18343 Ebelin lactone Inhibitor 96.0% Unkown
HY-107275 Ebeiedinone Inhibitor 99.90% Unkown
HY-N2284 Sophoflavescenol Inhibitor 98.78% Unkown
HY-155140 BChE-IN-17 Inhibitor 99.07% Unkown
HY-N4191 Isorosmanol Inhibitor 99.66% Unkown
HY-121072 ASS234 Inhibitor 99.6% Unkown
HY-122203A PCS1055 Inhibitor 98.02% Unkown
HY-164130 AChE-IN-65 Inhibitor / Unkown
HY-119979 Cardanol monoene 99.51% Unkown
HY-115910A Y13g dihydrochloride Inhibitor 99.89% Unkown
HY-N5120 Dihydrowithaferin A Inhibitor 99.72% Unkown
HY-119577 Ubretid 99.0% Yes
HY-B2029 Phosalone Inhibitor 98.04% Unkown
HY-B1120 Temephos Inhibitor 99.35% Unkown
HY-B0830S Isoprocarb-d3 Inhibitor 99.95% Unkown
HY-114803 Kokusaginine Inhibitor 98% Unkown
HY-N2176A (±)-Marmesin 95.0% Unkown
HY-N7263 Galanthamine N-Oxide Inhibitor 99.90% Unkown
HY-110389 Pitofenone hydrochloride Inhibitor 99.88% Unkown
HY-N0749 Jatrorrhizine Inhibitor / Unkown
HY-19651A Zanapezil Inhibitor 99.63% Unkown
HY-N12581 Kuwanon U Inhibitor 97.30% Unkown
HY-N0226 Epiberberine Inhibitor 98.46% Unkown
HY-N10488 BChE-IN-11 Inhibitor 98.78% Unkown
HY-Z8890 Norneostigmine Inhibitor 98.93% Unkown
HY-N1989 Bacoside A Modulator / Unkown
HY-105327 P11149 Inhibitor 99.23% Unkown
HY-149212 SD-6 Inhibitor ≥98.0% Unkown
HY-151368 AChE/BChE-IN-10 Inhibitor 99.67% Unkown
HY-103373 PE154 Inhibitor 99.01% Unkown
HY-19651B Zanapezil fumarate Inhibitor 99.63% Unkown
HY-W550259 ​Coroxon Inhibitor / Unkown
HY-N7346 Lucidadiol Inhibitor 98.0% Unkown
HY-126765 Territrem B Inhibitor ≥95.0% Unkown
HY-W004287 Methyl tridecanoate Inhibitor 99.75% Unkown
HY-Y0504S4 Trimethylammonium chloride-d6 Inhibitor 99.35% Unkown
HY-134137 Donepezil N-oxide Inhibitor 99.9% Unkown
HY-146678 HDAC6-IN-5 Inhibitor / Unkown
HY-151436 ZLMT-12 Inhibitor / Unkown
HY-148412 Monarsen Inhibitor / Unkown
HY-144272 AChE-IN-5 Inhibitor / Unkown
HY-181861 AChE/MAO-B-IN-9 Inhibitor / Unkown
HY-178017 BChE/hCA II-IN-1 Inhibitor / Unkown
HY-170561 AChE/BuChE-IN-6 Inhibitor / Unkown
HY-178141 AChE/BuChE-IN-7 Inhibitor / Unkown
HY-118222 KBR 2822 Inhibitor / Unkown
HY-106901B Asoxime dimesylate Inhibitor / Unkown
HY-174328 BChE/AChE-IN-1 Inhibitor / Unkown
HY-144389 hAChE/Aβ1-42-IN-1 Inhibitor / Unkown
HY-179711 AChE/BChE-IN-32 Inhibitor / Unkown
HY-180225 AChE-IN-101 Inhibitor / Unkown
HY-W165085 1,10-Bis(pyridinium)decane Inhibitor 99.66% Unkown
HY-172461 MAO-IN-6 Inhibitor / Unkown
HY-161512 hAChE/hBACE-1-IN-4 Inhibitor / Unkown
HY-N18289 8-Hydroxydihydrochelerythrine Inhibitor / Unkown
HY-180891 Multitarget AD-IN-4 Inhibitor / Unkown
HY-180892 Multi-kinase-IN-10 Inhibitor / Unkown
HY-157532 AChE-IN-55 Inhibitor / Unkown
HY-149300 SB-1436 Inhibitor / Unkown
HY-173152 AChE/BChE-IN-26 Inhibitor / Unkown
HY-158092 ChEs/MAOs-IN-2 Inhibitor / Unkown
HY-143291 AChE-IN-9 Inhibitor / Unkown
HY-175474 AChE-IN-93 Inhibitor / Unkown
HY-147846 AChE/PDE4-IN-1 Inhibitor / Unkown
HY-181445 NSC 620023 TFA Inhibitor / Unkown
HY-103374B (±)Phenserine Inhibitor / Unkown
HY-149237 hAChE-IN-2 Inhibitor / Unkown
HY-169962 hCA I-IN-4 Inhibitor / Unkown
HY-106412 Stacofylline Inhibitor / Unkown
HY-170417 hAChE/hBuChE/GSK-3β-IN-1 Inhibitor / Unkown
HY-178750 AChE-IN-96 Inhibitor / Unkown
HY-184159 AChE/BChE/MAO-A-IN-2 Inhibitor / Unkown
HY-132903 eeAChE-IN-1 Inhibitor / Unkown
HY-162338 BChE-IN-29 Inhibitor / Unkown
HY-163909 AChE-IN-72 Inhibitor / Unkown
HY-115910 Y13g Inhibitor / Unkown
HY-158978 Multitarget AD inhibitor-2 Inhibitor / Unkown
HY-162933 AChE-IN-77 Inhibitor / Unkown
HY-175973 AChE/BChE-IN-30 Inhibitor / Unkown
HY-105853 Pitofenone Inhibitor / Unkown
HY-183341 sEH/AChE-IN-5 / Unkown
HY-170925 AChE-IN-81 Inhibitor / Unkown
HY-147870 COX-2-IN-22 Inhibitor / Unkown
HY-174381 BChE-IN-41 Inhibitor / Unkown
HY-180946 AChE-IN-105 Inhibitor / Unkown
HY-180819 AChE/BChE-IN-33 Inhibitor / Unkown
HY-134006 Stemoninine Inhibitor / Unkown
HY-184140 AChE-IN-117 Inhibitor / Unkown
HY-180358 Gallamine Inhibitor / Unkown
HY-W800535 Cryptolepine Inhibitor / Unkown
HY-184796 AChE-IN-119 Inhibitor / Unkown
HY-149288 hAChE/hBACE-1-IN-2 Inhibitor / Unkown
HY-149087 MR2938 Inhibitor / Unkown
HY-175524 BChE/MAO-B-IN-2 Inhibitor / Unkown
HY-181503 AChE/BuChE-IN-8 Inhibitor / Unkown
HY-157296 AChE-IN-47 Inhibitor / Unkown
HY-161311 AChE/BChE-IN-18 Inhibitor / Unkown
HY-149211 AChE/BChE-IN-12 Inhibitor / Unkown
HY-168241 Flucopride Inhibitor / Unkown
HY-N12388 AChE-IN-46 Inhibitor / Unkown
HY-161507 hCAI/II-IN-8 Inhibitor / Unkown
HY-162681 eeAChE-IN-3 Inhibitor / Unkown
HY-N15452 Eseramine Inhibitor / Unkown
HY-161243 AChE-IN-56 Inhibitor / Unkown
HY-162812 H3R antagonist 4 Inhibitor / Unkown
HY-108048A Desoxypeganine hydrochloride Inhibitor / Unkown
HY-150728 AChE-IN-22 Inhibitor / Unkown
HY-180842 MAO-B-IN-50 Inhibitor / Unkown
HY-Y0504S1 Trimethylammonium chloride-d10 Inhibitor 98.0% Unkown
HY-149273 hBChE-IN-1 Inhibitor / Unkown
HY-184791 AChE-IN-120 Inhibitor / Unkown
HY-N19871 Monogynol A Inhibitor / Unkown
HY-174419 TFSeB Inhibitor / Unkown
HY-180146 BChE-IN-48 Inhibitor / Unkown
HY-131971 AChE/BChE-IN-1 Inhibitor / Unkown
HY-178943 Neuroprotective agent 15 Inhibitor / Unkown
HY-107272 Chuanbeinone Inhibitor / Unkown
HY-157440 AChE/Aβ-IN-3 Inhibitor / Unkown
HY-N17425 Lakoochin C Inhibitor / Unkown
HY-144392 AChE/BuChE-IN-1 Inhibitor / Unkown
HY-172884 MDAR-IN-1 Inhibitor / Unkown
HY-155713 AChE-IN-34 Inhibitor / Unkown
HY-169961 BChE-IN-38 Inhibitor / Unkown
HY-N2898 Artanin Inhibitor ≥90.0% Unkown
HY-Y0504S Trimethylammonium chloride-13c3,d9 Inhibitor 98% Unkown
HY-180113 AChE-IN-100 Inhibitor / Unkown
HY-N2511S Trimyristin--d15 Modulator / Unkown
HY-172460 AChE/BChE/MAO-B-IN-5 Inhibitor / Unkown
HY-174399 AChE/BChE-IN-27 Inhibitor / Unkown
HY-N17775 Scutellarein 4'-methyl ether 7-O-glucuronide Inhibitor / Unkown
HY-146762 MAO-B-IN-7 Inhibitor / Unkown
HY-N10701 AChE/BChE-IN-11 Inhibitor / Unkown
HY-147952 AChE-IN-20 Inhibitor / Unkown
HY-N16739 Circumdatin C Inhibitor / Unkown
HY-162591 MR33317 Inhibitor / Unkown
HY-B0916S Propoxur-d3 Inhibitor / Unkown
HY-180243 AChE-IN-102 Inhibitor / Unkown
HY-184776 Dyclonine Inhibitor / Unkown
HY-135450 Dimefluthrin / Unkown
HY-N12423 Bis-(-)-8-demethylmaritidine Inhibitor / Unkown
HY-182333 AChE-IN-112 Inhibitor / Unkown
HY-170938 AChE-IN-82 Inhibitor / Unkown
HY-181167 AChE/BChE-IN-34 Inhibitor / Unkown
HY-168603 AChE/CA I-IN-1 Inhibitor / Unkown
HY-158334 NDs-IN-1 Inhibitor / Unkown
HY-168731 AChE/BChE-IN-25 Inhibitor / Unkown
HY-169163 BChE-IN-36 Inhibitor / Unkown
HY-181110 MAO-A-IN-4 Inhibitor / Unkown
HY-159880 AChE/BChE-IN-24 Inhibitor / Unkown
HY-101653 MHP 133 Inhibitor / Unkown
HY-115841 Isatin-O Activator / Unkown
HY-146035 AChE-IN-14 Inhibitor / Unkown
HY-165341 SCR1693 Inhibitor / Unkown
HY-175006 AChE-IN-91 Inhibitor / Unkown
HY-151152 AChE-IN-24 Inhibitor / Unkown
HY-122080 Memoquin Inhibitor / Unkown
HY-175658 AChE/BChE-IN-29 Inhibitor / Unkown
HY-W746884 2-Methyl-2-butenyl (E)-Caffeate Inhibitor / Unkown
HY-159116 AChE-IN-69 Inhibitor / Unkown
HY-158261 AChE-IN-63 Inhibitor / Unkown
HY-182254 AChE/BChE-IN-35 Inhibitor / Unkown
HY-127087 Isogarcinol Inhibitor / Unkown
HY-119292 AP2238 Inhibitor / Unkown
HY-144790 AChE-IN-12 Inhibitor / Unkown
HY-144388 ChE/Aβ1-42-IN-1 Inhibitor / Unkown
HY-181161 AChE-IN-107 Inhibitor / Unkown
HY-176439 AChE-IN-88 Inhibitor / Unkown
HY-175856 AChE-IN-95 Inhibitor / Unkown
HY-168052 hAChE-IN-9 Inhibitor / Unkown
HY-155284 K1833 Inhibitor / Unkown
HY-163441 BChE-IN-31 Inhibitor / Unkown
HY-115919 AChE-IN-8 Inhibitor / Unkown
HY-W053641 (E)-2-Nitrocinnamic acid Inhibitor / Unkown
HY-120131 Cyanofenphos Inhibitor / Unkown
HY-175300 AChE-IN-92 Inhibitor / Unkown
HY-162036 α-Amylase/α-Glucosidase-IN-7 Inhibitor / Unkown
HY-123887 Manumycin B Inhibitor / Unkown
HY-144775 AChE-IN-10 Inhibitor / Unkown
HY-152111 AChE/MAO-B-IN-3 Inhibitor / Unkown
HY-157981 AChE-IN-60 Inhibitor / Unkown
HY-151260 AChE/BACE1/GSK3β-IN-1 Inhibitor / Unkown
HY-149272 tau/Aβ40 aggregation-IN-1 Inhibitor / Unkown
HY-W585905 Trimethylammonium chloride-13C3 Inhibitor / Unkown
HY-Y0504S2 Trimethylammonium chloride-15N Inhibitor / Unkown
HY-N11641 Methyl ganoderate A acetonide Inhibitor / Unkown
HY-155714 AChE-IN-35 Inhibitor / Unkown
HY-177798 AChE-IN-98 Inhibitor / Unkown
HY-165281 Chondrocurine Inhibitor / Unkown
HY-180155 Keap1/Nrf2/ARE activator 2 Inhibitor / Unkown
HY-184279 JDS364 Activator / Unkown
HY-183303 AChE-IN-116 Inhibitor / Unkown
HY-159898 AChE/BChE-IN-23 Inhibitor / Unkown
HY-N10423 Cubebin Inhibitor / Unkown
HY-158695 Dual AChE-MAO B-IN-4 Inhibitor / Unkown
HY-162915 AChE-IN-75 Inhibitor / Unkown
HY-181865 BuChE-IN-22 Inhibitor / Unkown
HY-152232 BChE-IN-15 Inhibitor / Unkown
HY-159482 SBN-284 Inhibitor / Unkown
HY-B0364AS Dyclonine-d9 hydrochloride Inhibitor / Unkown
HY-N16715 Monardic acid A Inhibitor / Unkown
HY-161508 AChE/BChE-IN-19 Inhibitor / Unkown
HY-182290 AChE/BChE-IN-36 Inhibitor / Unkown
HY-155366 hAChE-IN-6 Inhibitor / Unkown
HY-161842 AChE-IN-67 Inhibitor / Unkown
HY-149287 hAChE/hBACE-1-IN-1 Inhibitor / Unkown
HY-157437 AChE/BChE-IN-16 Inhibitor / Unkown
HY-151562 AChE/BuChE/MAO-B-IN-1 Inhibitor / Unkown
HY-143252 CEase-IN-1 Inhibitor / Unkown
HY-155085 hAChE-IN-3 Inhibitor / Unkown
HY-N11962A 2,3,9,10-Tetrahydroxyberberine bromide Inhibitor / Unkown
HY-174462 AChE-IN-90 Inhibitor / Unkown
HY-N15710 Magnotriol B Inhibitor / Unkown
HY-N9846 Luteolin 5,3'-dimethyl ether / Unkown
HY-N16645 Plasiaticine B Inhibitor / Unkown
HY-173144 AChE-IN-85 Inhibitor / Unkown
HY-163537 AChE/BuChE-IN-5 Inhibitor / Unkown
HY-161156 BChE-IN-26 Inhibitor / Unkown
HY-151927 AChE-IN-28 Inhibitor / Unkown
HY-105157 Icopezil Inhibitor / Unkown
HY-132904 eeAChE-IN-2 Inhibitor / Unkown
HY-N19855 Merulinic acid Inhibitor / Unkown
HY-B0916R Propoxur (Standard) Inhibitor 99.04% Unkown
HY-115973 AChE-IN-11 Inhibitor / Unkown
HY-183796 GFAP/NF-κB/APOE/NLRP3-IN-1 Inhibitor / Unkown
HY-181851 AChE-IN-109 Inhibitor / Unkown
HY-N17416 ω-Hydroxydigitoemodin Inhibitor / Unkown
HY-170583 hAChE-IN-10 Inhibitor / Unkown
HY-151885 Dual AChE-MAO B-IN-3 Inhibitor / Unkown
HY-W856819 Eseroline Inhibitor / Unkown
HY-161150 AChE/BChE-IN-17 Inhibitor / Unkown
HY-181744 AChE-IN-108 Inhibitor / Unkown
HY-146959 K203 Activator / Unkown
HY-146663A AChE/BChE-IN-3 hydrochloride Inhibitor / Unkown
HY-181248 BChE-IN-49 Inhibitor / Unkown
HY-N10384 AChE-IN-17 Inhibitor / Unkown
HY-174464 AChE/BChE-IN-28 Inhibitor / Unkown
HY-157441 AChE/Aβ-IN-4 Inhibitor / Unkown
HY-181119 AChE-IN-106 Inhibitor / Unkown
HY-163126 AChE-IN-52 Inhibitor / Unkown
HY-N15707 Isocorydine N-oxide Inhibitor / Unkown
HY-184742 AJ-4 Inhibitor / Unkown
HY-143465 BChE-IN-5 Inhibitor / Unkown
HY-182786 MAO-B-IN-56 Inhibitor / Unkown
HY-181141 AChE/MAO-B-IN-8 Inhibitor / Unkown
HY-144762 K027 Inhibitor / Unkown
HY-49373 AChE-IN-64 Inhibitor / Unkown
HY-152110 AChE/MAO-IN-2 Inhibitor / Unkown
HY-175523 MAO-B-IN-48 Inhibitor / Unkown
HY-144689 BChE-IN-3 Inhibitor / Unkown
HY-157978 AChE-IN-59 Inhibitor / Unkown
HY-175758 AChE-IN-94 Inhibitor / Unkown
HY-177958 ACS03 Activator / Unkown
HY-W750970 2-Acetoxyacorenone Inhibitor / Unkown
HY-179496 ChE/GSK-3β-IN-1 Inhibitor / Unkown
HY-155822 TZ3O Inhibitor 98.17% Unkown
HY-181041 Multitarget AD-IN-5 Inhibitor / Unkown
HY-163514 hAChE-IN-8 Inhibitor / Unkown
HY-169162 hBChE-IN-3 Inhibitor / Unkown
HY-157982 BChE-IN-28 Inhibitor / Unkown
HY-156372 AChE-IN-44 Inhibitor / Unkown
HY-N21824 (+)-(3S)-ψ-Ribalinine Inhibitor / Unkown
HY-N21822 (+)-(R)-Ribalinine Inhibitor / Unkown
HY-179621 EQ-04 Modulator / Unkown
HY-157382 AChE-IN-51 Inhibitor / Unkown
HY-152113 AChE/BChE/MAO-B-IN-3 Inhibitor / Unkown
HY-N10032 (3β,5α,6α,16β)-8,14-Didehydrocevane-3,6,16,20-tetrol Inhibitor / Unkown
HY-161142 Carbonic anhydrase/AChE-IN-1 Inhibitor / Unkown
HY-150545 AChE-IN-21 Inhibitor / Unkown
HY-170389 BChE-IN-39 Inhibitor / Unkown
HY-N21823 Methyl isoplatydesmine Inhibitor / Unkown
HY-162693 AChE-IN-68 Inhibitor / Unkown
HY-162606 MAO-A/B-IN-3 Inhibitor / Unkown
HY-184935 Neuroprotective agent 18 Inhibitor / Unkown
HY-170560 AChE/hCA I-IN-1 Inhibitor / Unkown
HY-179122 BChE-IN-45 Inhibitor / Unkown
HY-180552 AChE-IN-104 Inhibitor / Unkown
HY-N2219 Picfeltarraegenin X Inhibitor / Unkown
HY-182001 Multi-kinase-IN-13 Inhibitor / Unkown
HY-152109 AChE/MAO-IN-1 Inhibitor / Unkown
HY-147938 AChE-IN-19 Inhibitor / Unkown
HY-19181 CI-1002 Antagonist / Unkown
HY-N16447 Territrem C / Unkown
HY-183760 AChE/BChE-IN-37 Inhibitor / Unkown
HY-145235 AChE-IN-4 / Unkown
HY-159081 AChE/BChE-IN-20 Inhibitor / Unkown
HY-172219 CUR-IPA Inhibitor / Unkown
HY-157087 AChE/MAO-B-IN-4 Inhibitor / Unkown
HY-147939 AChE/BuChE-IN-3 Inhibitor / Unkown
HY-180114 NSS-18 Inhibitor / Unkown
HY-149090 AChE/BuChE/MAO-B-IN-2 / Unkown
HY-N10781 Isograndifoliol Inhibitor / Unkown
HY-181811 PJ17 Inhibitor / Unkown
HY-180783 AChE/BChE/MAO-A-IN-1 Inhibitor / Unkown
HY-146315 AChE/BChE-IN-6 Inhibitor / Unkown
HY-185347 AChE-IN-114 Inhibitor / Unkown
HY-145695 Dual AChE-MAO B-IN-1 Inhibitor / Unkown
HY-183949 Insecticidal agent 33 Inhibitor / Unkown
HY-152112 AChE/BChE/MAO-B-IN-2 Inhibitor / Unkown
HY-162639 α-Glucosidase-IN-68 Inhibitor / Unkown
HY-149233 hAChE-IN-1 Inhibitor / Unkown
HY-N8547A (Rac)-Sclerone Inhibitor / Unkown
HY-178433 BChE/p38-α MAPK-IN-2 Inhibitor / Unkown
HY-181597 LINS05414 Inhibitor / Unkown
HY-117710A AD-35 free base Inhibitor / Unkown
HY-112013 Isodimethoate Inhibitor / Unkown
HY-113905 ZINC12613047 Inhibitor / Unkown
HY-183403 Ganstigmine Inhibitor / Unkown
HY-18039 WAY-361789 Agonist / Unkown
HY-165600 Trimedoxime dichloride Activator / Unkown
HY-161029 T14-A24 Inhibitor / Unkown
HY-N19401 Vescalagin Inhibitor / Unkown
HY-W588214 Phorate sulfone Inhibitor / Unkown
HY-W332450 Demeton-S Inhibitor / Unkown
HY-116041 Anabasamine Inhibitor / Unkown
HY-120042 Heptenophos Inhibitor / Unkown
HY-180506 Tyrosinase-IN-47 Inhibitor / Unkown
HY-169173 AL284 Inhibitor / Unkown
HY-N12833 Dihydrokaempferol-3-O-β-D-glucoside Inhibitor / Unkown
HY-W049312 7-Methoxytacrine Inhibitor / Unkown
HY-183066 AChE-IN-115 Inhibitor / Unkown
HY-175607 AChE/nAChR-IN-1 Inhibitor / Unkown
HY-180448 Galactamine Inhibitor / Unkown
HY-N1151 Thunberginol C Inhibitor / Unkown
HY-W740798 4'-O-Methylcatechin Inhibitor / Unkown
HY-N2971 Buxbodine B Inhibitor / Unkown
HY-115650 TAE-1 Inhibitor 96.17% Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992076 Anti-Candida auris β-1, 3 glucans Antibody (2G8) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ACHE NCBI NCBI:43