Search Result

Results for "

lys-

" in MedChemExpress (MCE) Product Catalog:

By Targets:	15-PGDH (1) 5-HT Receptor (1) ABA Receptor (1) Acyltransferase (1) ADAMTS (2) ADC Linker (44) ADC Payload (2) Adenylate Cyclase (12) Adrenergic Receptor (9) Akt (25) Amino Acid Decarboxylase (2) Amino Acid Derivatives (90) Aminopeptidase (4) AMPK (8) Amylases (1) Amylin Receptor (26) Amyloid-β (107) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (9) Angiotensin Receptor (8) Angiotensin-converting Enzyme (ACE) (18) Annexin A (5) Antibiotic (51) APC (2) Apelin Receptor (APJ) (18) Apolipoprotein (9) Apoptosis (114) Arenavirus (6) Arf Family GTPase (2) Arp2/3 Complex (3) Arrestin (6) ASCT (1) Atg8/LC3 (1) ATM/ATR (1) Aurora Kinase (1) Autophagy (23) Bacterial (387) Bcl-2 Family (11) BCL6 (1) Bcr-Abl (3) Beclin1 (1) Beta-lactamase (1) Beta-secretase (3) Biochemical Assay Reagents (139) BMI1 (1) Bombesin Receptor (8) Bradykinin Receptor (13) Btk (3) c-Fms (1) c-Kit (1) c-Met/HGFR (1) c-Myc (2) Cadherin (3) Calcium Channel (58) Calmodulin (9) CaMK (19) Cannabinoid Receptor (5) Carboxypeptidase (1) Casein Kinase (7) Caspase (22) Cathepsin (14) CCR (6) CD47 (4) CD74 (2) CDK (11) CFTR (1) CGRP Receptor (37) Checkpoint Kinase (Chk) (4) CHIKV (1) Chloride Channel (3) Cholecystokinin Receptor (5) Cholinesterase (ChE) (5) Claudin (1) CMV (3) Collagen (15) Complement System (13) Connexin (2) COX (3) CRFR (24) CXCR (28) Cytochrome P450 (5) DAPK (3) Dengue Virus (9) Deubiquitinase (3) Dipeptidyl Peptidase (3) DNA Alkylator/Crosslinker (5) DNA Methyltransferase (1) DNA-PK (2) DNA/RNA Synthesis (15) Dopamine Receptor (6) Drug Derivative (32) Drug Intermediate (11) Drug-Linker Conjugates for ADC (25) Dynamin (3) DYRK (3) E1/E2/E3 Enzyme (4) EBV (5) EGFR (20) Elastase (3) Endogenous Metabolite (54) Endothelin Receptor (18) Enteropeptidase (1) Enterovirus (6) Ephrin Receptor (1) Epigenetic Reader Domain (9) ERK (31) Estrogen Receptor/ERR (5) Eukaryotic Initiation Factor (eIF) (2) Exosomes (2) Factor Xa (1) FAK (6) Ferroportin (1) Ferroptosis (3) FGFR (8) Flavivirus (3) FLT3 (1) Fluorescent Dye (76) Formyl Peptide Receptor (FPR) (14) FOXO (2) Fungal (53) Furin (2) FXR (4) G protein-coupled Bile Acid Receptor 1 (1) GABA Receptor (10) Galectin (2) Gap Junction Protein (8) GCGR (81) GHSR (21) Gli (1) GLP Receptor (60) Glucocorticoid Receptor (1) GLUT (2) Glutaminase (1) Glutathione Peroxidase (3) Glutathione S-transferase (1) Glycosidase (1) GnRH Receptor (10) GPR55 (1) GSK-3 (4) Hapten (1) HBV (1) HCV (6) HDAC (8) Heme Oxygenase (HO) (2) Hepcidin (2) Hexokinase (1) HIF/HIF Prolyl-Hydroxylase (3) Histamine Receptor (3) Histone Acetyltransferase (3) Histone Demethylase (6) Histone Methyltransferase (9) HIV (64) HIV Integrase (2) HPV (3) HSP (8) HSV (7) Huntingtin (1) IFNAR (19) IGF-1R (5) iGluR (19) IKK (7) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (14) Insecticide (2) Insulin Receptor (45) Integrin (47) Interleukin Related (54) IPK Superfamily (2) IRAK (1) Isotope-Labeled Compounds (79) JAK (6) JNK (28) Kallikrein (3) Keap1-Nrf2 (5) Kisspeptin Receptor (1) LDLR (6) Ligands for E3 Ligase (1) Ligands for Target Protein for PROTAC (2) LIM Kinase (LIMK) (1) Lipase (1) Liposome (9) Lipoxygenase (1) LPL Receptor (2) LRRK2 (2) mAChR (4) MAPKAPK2 (MK2) (4) MARCKS (8) Mas-related G-protein-coupled Receptor (MRGPR) (5) MCHR1 (GPR24) (1) MDM-2/p53 (19) MEK (3) Melanocortin Receptor (47) mGluR (2) MHC (21) Microtubule/Tubulin (7) Mineralocorticoid Receptor (2) Mitochondrial Metabolism (11) Mitophagy (1) Mitosis (2) MMP (35) Monoamine Transporter (1) Motilin Receptor (5) mTOR (4) MyD88 (4) Myosin (5) N-myristoyltransferase (2) Na+/Ca2+ Exchanger (1) Na+/K+ ATPase (2) nAChR (16) NADH Dehydrogenase (1) NADPH Oxidase (5) Natriuretic Peptide Receptor (NPR) (7) Necroptosis (3) Nectin-4 (1) NEKs (1) Neurokinin Receptor (45) Neuromedin U Receptor (NMUR) (3) Neuropeptide B/W Receptor (7) Neuropeptide S Receptor (3) Neuropeptide Y Receptor (43) Neurotensin Receptor (10) NF-κB (34) NO Synthase (18) NOD-like Receptor (NLR) (3) Notch (2) Nuclear Factor of activated T Cells (NFAT) (1) Nuclear Hormone Receptor 4A/NR4A (5) Opioid Receptor (35) Orexin Receptor (OX Receptor) (5) Orphan GPCR (1) Orphan Receptor (1) Oxytocin Receptor (3) P-glycoprotein (1) P-selectin (3) P2X Receptor (3) p38 MAPK (25) p62 (1) PACAP Receptor (26) PAI-1 (5) PAK (3) Parasite (9) PCSK9 (2) PD-1/PD-L1 (20) PDGFR (2) PDHK (1) PDK-1 (2) Peptide-Drug Conjugates (PDCs) (4) PERK (8) PGC-1α (2) Phosphatase (7) Phosphodiesterase (PDE) (3) Phospholipase (4) Phytohormone (2) PI3K (10) Piezo Channel (4) PKA (12) PKC (43) PKG (9) Platelet-activating Factor Receptor (PAFR) (1) Porcupine (1) Potassium Channel (77) PPAR (2) Pregnane X Receptor (PXR) (1) Prion Protein (1) Prostaglandin Receptor (4) PROTAC Linkers (11) PROTACs (7) Protease Activated Receptor (PAR) (9) Proteasome (5) Proton Pump (3) PSMA (6) PTHR (10) Pyroptosis (1) Pyruvate Kinase (1) RABV (5) RAD51 (1) Radionuclide-Drug Conjugates (RDCs) (38) Raf (1) Ras (13) Reactive Oxygen Species (ROS) (43) Reference Standards (7) Renin (3) RET (1) Reverse Transcriptase (4) Ribosomal S6 Kinase (RSK) (3) RIP kinase (1) ROCK (1) RUNX (1) RXFP Receptor (6) SARS-CoV (16) SDCBP (2) Ser/Thr Kinase (1) Ser/Thr Protease (19) Serotonin Transporter (1) Serpin (1) Sex Pheromone (2) Sirtuin (6) Small Interfering RNA (siRNA) (3) SOD (1) Sodium Channel (73) Somatostatin Receptor (52) SOS1 (2) Src (8) STAT (13) STING (1) Survivin (4) Syk (2) Tau Protein (19) Telomerase (1) TET Protein (2) TGF-beta/Smad (17) TGF-β Receptor (17) Thrombin (8) Thrombopoietin Receptor (3) Thymidylate Synthase (1) Thyroid Hormone Receptor (21) TMV (1) TNF Receptor (29) Toll-like Receptor (TLR) (24) Topoisomerase (3) Transmembrane Glycoprotein (13) TREM receptor (4) Trk Receptor (1) TRP Channel (14) Urotensin Receptor (5) Vasopressin Receptor (13) VEGFR (12) Virus Protease (6) VSV (1) Wnt (4) YAP (6) α-synuclein (8) β-catenin (6)
By Research Areas:	Cancer (698) Cardiovascular Disease (286) Endocrinology (153) Infection (535) Inflammation/Immunology (538) Metabolic Disease (418) Neurological Disease (705)
Click Chemistry:	ADC Synthesis (3) TCO (2) Labeling and Fluorescence Imaging (5) DBCO (1) Azide (33) Tetrazine (1) Alkynes (7)
Oligonucleotides:	Pegylated Lipids (1) Cap Analogs (2) Cholesterol (1)

3124

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

3370

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12855A

Lys05 4 Publications Verification lys01 trihydrochloride	Autophagy	Cancer
Lys05 (Lys01 trihydrochloride) is a novel lysosomal autophagy inhibitor with IC₅₀ values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay.

HY-W008176

*Fmoc-Lys-OH*	Amino Acid Derivatives	Others
Fmoc-Lys-OH is a lysine derivative .

HY-101982

Lys-SMCC-DM1 1 Publications Verification lys-Nε-MCC-DM1	Drug-Linker Conjugates for ADC	Cancer
Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is a HER2-targeting ADC with a tubulin polymerization inhibitor DM1. Lys-SMCC-DM1 can be used in the research of breast cancer .

HY-131157

Lys(MMT)-PAB-oxydiacetamide-PEG8-N3	ADC Linker	Cancer
Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable antibody agent conjugate linker used in the synthesis of antibody-drug conjugates (ADCs) . Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W010975

*Fmoc-Lys-OH hydrochloride*	ADC Linker PROTAC Linkers	Cancer
Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-131409

*D-Val-Leu-Lys-pNA dihydrochloride* D-Val-Leu-lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

HY-W009004

Trilysine lys-lys-lys; H-lys-lys-lys-OH	Biochemical Assay Reagents	Others
Trilysine is a tripeptide and also a substrate for specific peptidases. Trilysine serves as a hydrolytic substrate for the tripeptide-specific aminopeptidase TP and the oligopeptidase OP .

HY-P3205

Lysyl endopeptidase, Achromobacter sp 1 Publications Verification lys-C	Biochemical Assay Reagents	Others
Lysyl endopeptidase, Achromobacter sp (Lys-C) catalyzes carboxyl oxygen exchange reaction. Lysyl endopeptidase has higher substrate binding affinities and higher catalytic rates at the acidic pHs than at the alkaline pHs .

HY-129724A

α-MSH (11-13) acetate ACTH-(11-13) acetate; lys-Pro-Val acetate; H-lys-Pro-Val-OH acetate		Infection Metabolic Disease
α-MSH (11-13) acetate is a melanocortin-1 receptor ligand and anti-inflammatory agent. α-MSH (11-13) acetate triggers acute intracellular calcium elevation under specific costimulation or pathway inhibition conditions. α-MSH (11-13) acetate inhibits TNF-α-induced NF-κB activation, GPx activity, HIV replication, as well as colony formation of S. aureus and C. albicans. α-MSH (11-13) acetate is applicable to the research of Staphylococcus aureus infection, Candida albicans infection, human immunodeficiency virus infection, traumatic brain injury, corneal epithelial wound and inflammatory bowel disease .

HY-137298

LYS006 LTA4H-IN-1	Aminopeptidase	Inflammation/Immunology
LTA4H-IN-1 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) extracted from patent WO2015092740A1, example 29, has an IC₅₀ of 2 nM. LTA4H-IN-1 can be used for the research of inflammatory and autoimmune disorders .

HY-W007020

*Fmoc-Lys-OAll.HCl*	Amino Acid Derivatives	Others
Fmoc-Lys-OAll.HCl is a lysine derivative .

HY-P0004

Lysipressin 2 Publications Verification lysine vasopressin; [lys8]-Vasopressin	Adenylate Cyclase Oxytocin Receptor	Cardiovascular Disease Neurological Disease
Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity .

HY-131035

Lys-CoA TFA lys-coenzyme A	Histone Acetyltransferase	Cancer
Lys-CoA TFA is a selective p300 histone acetyltransferase (HAT) inhibitor (IC₅₀=50-500 nM). Lys-CoA TFA displays >100-fold selectivity for p300 over PCAF (IC₅₀=200 μM). Lys-CoA TFA inhibits p300 HAT activity-dependent transcriptional activation .

HY-P2544

*[Lys8, Lys9]-Neurotensin (8-13)* JMV438	Neurotensin Receptor	Neurological Disease
[Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with K_i values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively .

HY-W007618

*Boc-Lys-OH*	Amino Acid Derivatives Biochemical Assay Reagents Drug Intermediate	Others
Boc-Lys-OH is an amino acid derivative. Boc-Lys-OH plays a key role in peptide synthesis and redox activity research .

HY-114788

Lysylcysteine L-lysyl-L-cysteine; lys-Cys; H-lys-Cys-OH	Amino Acid Derivatives	Others
Lysylcysteine (L-Lysyl-L-cysteine) is a dipeptide composed of lysine and cysteine.

HY-P4319

*Boc-Glu-Lys-Lys-AMC*	Fluorescent Dye	Others
Boc-Glu-Lys-Lys-AMC is a sensitive fluorogenic substrate for urokinase-activated plasmin .

HY-P1350

*H-Lys-Trp-Lys-OH*	Bacterial	Infection
H-Lys-Trp-Lys-OH is a small molecule peptide which displays antibacterial and antiviral activities extracted from patent CN 104072579 A, Compound AMP12.

HY-177307

*Mal-Val-Lys-PAB-MMAE*	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
Mal-Val-Lys-PAB-MMAE is a drug-linker conjugate for ADC. Mal-Val-Lys-PAB-MMAE consists of a Tubulin inhibitor (MMAE) (HY-15162) and a linker (Mal-Val-Lys-PAB). Mal-Val-Lys-PAB-MMAE can be used for synthesis of ADCs .

HY-13443B

*Exendin-4-Lys-azide TFA*	GCGR	Cardiovascular Disease Metabolic Disease Cancer
Exendin-4-Lys-azide TFA (Compound Ex40) is an azide derivative of Exendin-4-Lys-azide, Exendin-4, which can be used for coupling/click chemistry .

HY-W010989

*Gly-His-Lys* acetate**	Biochemical Assay Reagents Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
Gly-His-Lys acetate is a natural, circulating regulatory and antimicrobial tripeptide derived from extracellular matrix proteins. Gly-His-Lys acetate binds Cu ²⁺ to support copper enzyme activation, antioxidant processes, cellular bioenergetics, and the synthesis of elastin, collagen and catecholamines. Gly-His-Lys acetate regulates cell growth, differentiation and tissue repair, and exerts regenerative, anxiolytic, anti-inflammatory, analgesic and immunosuppressive activities. Gly-His-Lys acetate induces liver degenerative changes. Gly-His-Lys acetate can be used for the research of infections, anxiety, pain-related behaviors and immune-associated liver diseases .

HY-P1163A

*D[LEU4,LYS8]-VP TFA*	Vasopressin Receptor	Cardiovascular Disease Neurological Disease
D[LEU4,LYS8]-VP TFA is a selective agonist of vasopressin V_1b receptor, with the K_is of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V_1b receptor, respectively. D[LEU4,LYS8]-VP TFA has weak antidiuretic, vasopressor, and in vitro oxytocic activities .

HY-P3726

Lys-Gln-Ala-Gly-Asp-Val	Integrin	Inflammation/Immunology Cancer
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α_2bβ₃ integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs) .

HY-P4426A

Lys-Pro-AMC diTFA	Fluorescent Dye	Others
Lys-Pro-AMC diTFA is a fluorogenic substrate for the detection and measurement of the activity of specific enzymes .

HY-P4676

Lys-(Des-Arg9,Leu8)-Bradykinin	Bradykinin Receptor	Endocrinology
Lys-(Des-Arg9,Leu8)-Bradykinin is a bradykinin B1 receptor antagonist .

HY-129724

α-MSH (11-13) ACTH-(11-13); lys-Pro-Val; H-lys-Pro-Val-OH	Melanocortin Receptor Bacterial NF-κB Apoptosis Interleukin Related	Infection Neurological Disease Metabolic Disease Inflammation/Immunology
α-MSH (11-13) is a C-terminal tripeptide of α-MSH that can cross the blood-brain barrier. α-MSH (11-13) exhibits antipyretic, anti-inflammatory, and antibacterial activities. α-MSH (11-13) also exerts neuroprotective effects after traumatic brain injury by inhibiting excessive activation of microglia and reducing neuronal apoptosis. α-MSH (11-13) can be used in research related to traumatic brain injury, fever, and bacterial infections .

HY-P5413

*[Lys3]-Bombesin*	Cholecystokinin Receptor	Others
[Lys3]-Bombesin is a biological active peptide. (PET (Positron Emission Tomography) imaging of [Lys3]-bombesin is able to detect gastrin-releasing peptide receptor (GRPR) positive prostate cancer. An immunoconjugate of [Lys3]-bombesin and corresponding monoclonal antibody can specifically induce (CD64)-dependent monocyte and neutrophil-mediated lysis of small cell carcinoma.)

HY-135514

Lys-Phe H-lys-Phe-OH	Amino Acid Derivatives	Cardiovascular Disease
Lys-Phe is a dipeptide that inhibits both cell sickling and the gelation of solutions of sickle-cell haemoglobin .

HY-101982A

*(Rac)-Lys-SMCC-DM1* (Rac)-lys-Nε-MCC-DM1	Drug-Linker Conjugates for ADC	Cancer
(Rac)-Lys-SMCC-DM1 ((Rac)-Lys-Nε-MCC-DM1) is the racemate of Lys-SMCC-DM1 (HY-101982). Lys-SMCC-DM1 is a linker-payload component that has the potential to inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1 .

HY-N15829

*Cholyl-Lys-fluorescein sodium*	Fluorescent Dye	Metabolic Disease
Cholyl-Lys-fluorescein sodium is a fluorescein-labeled bile acid analog. Cholyl-Lys-fluorescein sodium mimics the physiological hepatobiliary properties of glycocholic acid. Cholyl-Lys-fluorescein sodium is efficiently taken up by the liver and rapidly excreted into bile in intact form in rats. Cholyl-Lys-fluorescein sodium can serve as a liver function assessment agent, bile salt transport probe, and liver-targeted carrier .

HY-P1591

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys For-Nle-Leu-Phe-Nle-Tyr-lys-OH	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist .

HY-103293A

Lys-Bradykinin TFA Kallidin (380-389) (human, porcine, bovine) TFA	Bradykinin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Lys-Bradykinin TFA is the TFA salt form of Lys-Bradykinin (HY-103293). Lys-Bradykinin TFA is a ligand for kallidin and bradykinin receptor, which can be generated by kininogen protein through enzymatic cleavage by the protease kallikrein. Lys-Bradykinin TFA serves as a vasodilator, which widens blood vessels and increases blood flow. Lys-Bradykinin TFA stimulates net Na+ influx, and contributes to DNA synthesis. Lys-Bradykinin TFA involves in vascular regulation, inflammation and pain sensation .

HY-164732

*Fmoc-Lys(DOTA)-OH*	Amino Acid Derivatives Biochemical Assay Reagents	Others
Fmoc-Lys (DOTA)-OH is an Fmoc-protected Lysine derivative with metal-chelating properties, containing the macrocyclic chelator DOTA. Fmoc-Lys (DOTA)-OH undergoes metallation with Tb or Lu. Fmoc-Lys (DOTA)-OH utilizes metal coordination to protect the carboxyl groups of DOTA. Fmoc-Lys (DOTA)-OH can be used in solid-phase peptide synthesis research .

HY-P4468

Lys-Ala-pNA	Dipeptidyl Peptidase	Others
Lys-Ala-pNA is hydrolytic substrate the of dipeptidyl peptidase (DPP) II with K_m of 0.42 mM .

HY-W048209

*Fmoc-Lys(Palmitoyl)-OH*	Amino Acid Derivatives	Others
Fmoc-Lys(Palmitoyl)-OH is a Fmoc-amino acid with long alkyl chains. Fmoc-Lys(Palmitoyl)-OH can be used for peptide synthesis .

HY-177307A

*Mal-Val-Lys-PAB-MMAE TFA*	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
Mal-Val-Lys-PAB-MMAE TFA is a drug-linker conjugate for ADC. Mal-Val-Lys-PAB-MMAE TFA consists of a Tubulin inhibitor (MMAE) (HY-15162) and a linker (Mal-Val-Lys-PAB). Mal-Val-Lys-PAB-MMAE TFA can be used for synthesis of ADCs .

HY-125083

Lys-D-Pro-Thr	Interleukin Related	Metabolic Disease
Lys-D-Pro-Thr, an IL-1beta analogue (Positions 193-195), is a potent IL-1 inhibitor .

HY-158118

Lys(CO-C3-p-I-Ph)-OMe	DNA-PK	Cancer
Lys(CO-C3-p-I-Ph)-OMe is a pharmacokinetic modifier (PK modifier) that can improve the PK properties of PSMA ligand molecules (such as Ac-PSMA-trillium). Lys(CO-C3-p-I-Ph)-OMe can increase the residence time of Ac-PSMA-trillium in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-OMe also reduces salivary gland absorption of Ac-PSMA-trillium, potentially extending its half-life. Ac-PSMA-trillium is a suitable PSMA-targeting compound that has different biological applications after modification with different radioactive isotopes. If labeled with ¹¹¹In, it can be used as DOTA chelating agent and imaging agent. Or labeled with ²²⁵Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .

HY-W010789

L-Lysyl-L-tyrosine-α-L-lysine H-lys-Tyr-lys-OH; lys-Tyr-lys	Amino Acid Derivatives	Others
L-Lysyl-L-tyrosine-α-L-lysine is a lysine derivative .

HY-114788A

Lysylcysteine TFA L-lysyl-L-cysteine TFA; lys-Cys TFA; H-lys-Cys-OH TFA	Amino Acid Derivatives	Others
Lysylcysteine (L-Lysyl-L-cysteine) TFA is a dipeptide composed of lysine and cysteine .

HY-P0004A

Lysipressin acetate 2 Publications Verification lysine vasopressin acetate; [lys8]-Vasopressin acetate	Adenylate Cyclase	Others
Lysipressin (Lysine vasopressin) acetate is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin acetate induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase .

HY-W327145

Lysylglutamic acid	Endogenous Metabolite	Infection
Lysylglutamic acid is a dipeptide formed by combining two amino acids, Lysine (Lys) and Glutamic acid (Glu). The K_i value of the membrane transporter PEPT1 was 1.3 mM .

HY-P10095

*D-Val-Phe-Lys-CMK* D-Val-Phe-lys Chloromethyl ketone	Ser/Thr Protease	Metabolic Disease
D-Val-Phe-Lys-CMK (D-Val-Phe-Lys Chloromethyl ketone) can inhibit plasmin activity .

HY-P11348

TG-MMP-Lys	MMP	Cancer
TG-MMP-Lys is an MMP-sensitive crosslinking peptide. TG-MMP-Lys is promising for research of fibrotic diseases (e.g., liver fibrosis) .

HY-P10095A

*D-Val-Phe-Lys-CMK diTFA* D-Val-Phe-lys Chloromethyl ketone diTFA	Ser/Thr Protease	Metabolic Disease
D-Val-Phe-Lys-CMK (D-Val-Phe-Lys Chloromethyl ketone) diTFA can inhibit plasmin activity .

HY-P4558

*H-Pro-Lys-OH*	Dipeptidyl Peptidase	Others
H-Pro-Lys-OH is a dipeptide containing proline and lysine, which can serve as a substrate for iminodipeptidase (prolinase). H-Pro-Lys-OH can also be used for the synthesis of polypeptides .

HY-P2673

Lys-Arg-Thr-Leu-Arg-Arg KRTLRR	EGFR	Others
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C .

HY-P4558A

*H-Pro-Lys-OH TFA*	Dipeptidyl Peptidase	Others
H-Pro-Lys-OH TFA is a dipeptide containing proline and lysine, which can serve as a substrate for iminodipeptidase (prolinase). H-Pro-Lys-OH TFA can also be used for the synthesis of polypeptides .

HY-P4341

*D-Val-Leu-Lys-AMC*	PAI-1 Fluorescent Dye	Others
D-Val-Leu-Lys-AMC is a selective fluorogenic peptide substrate of plasmin. D-Val-Leu-Lys-AMC can be used for the quantification of enzymatic activity of plasmin. Ex: 360-380 nm, Em: 440-460 nm .

HY-W419374

*ivDde-Lys(Fmoc)-OH*	Amino Acid Derivatives	Others
ivDde-Lys(Fmoc)-OH is a derivative of amino acid with protecting groups. ivDde-Lys(Fmoc)-OH can be used for peptide synthesis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P0017

Aprotinin 30+ Cited Publications	Cardiovascular Disease Natural Products Animals Disease Research Fields Source Classification	Influenza Virus Ser/Thr Protease
Aprotinin is a bovine pancreatic trypsin inhibitor (BPTI) inhibitor which inhibits trypsin and chymotrypsin with K_is of 0.06 pM and 9 nM, respectively.

HY-P0201

Substance P 30+ Cited Publications Neurokinin P	Structural Classification Natural Products Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Neurokinin Receptor Endogenous Metabolite
Substance P (Neurokinin P) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).

HY-P0063

Copper tripeptide 1 Publications Verification GHK-Cu	Natural Products Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Biochemical Assay Reagents
Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration .

HY-P0281

TAT TAT(47-57); HIV-1 TAT protein (47-57)	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	HIV
TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins .

HY-P1902

Cardiotoxin Analog (CTX) IV (6-12) 5+ Cited Publications	Cardiovascular Disease Natural Products Animals Disease Research Fields Source Classification	Apoptosis
Cardiotoxin Analog (CTX) IV (6-12) is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol). Cardiotoxin Analog (CTX) IV (6-12) was discovered in the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) is a chemically synthesized snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .

HY-105174

BPC 157	Alkaloids Pyrrole Alkaloids Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	JAK FAK
BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems .

HY-P0190

Iberiotoxin 2 Publications Verification	Cardiovascular Disease Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification	Potassium Channel
Iberiotoxin is a toxin isolated from Buthus tamulus scorpion venom. Iberiotoxin is a selective high conductance high conductance Ca ²⁺-activated K ⁺ channel inhibitor with a K_d of ~1 nM. Iberiotoxin does not block other types of voltage-dependent ion channels .

HY-P0173A

Chlorotoxin 2 Publications Verification	Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification Cancer	Chloride Channel
Chlorotoxin is a 36 amino-acid peptide from the venom of the Israeli scorpion Leiurus quinquestriatus with anticancer activity. Chlorotoxin is a chloride channel blocker.

HY-P2358

PSMα3	Structural Classification Natural Products Microorganisms Classification of Application Fields Inflammation/Immunology Disease Research Fields Source Classification	NF-κB p38 MAPK
PSMα3 is an inhibitor of NF-κB p65 and p38 MAPK. PSMα3 forms membrane pores and binds to residues of human insulin B chain to inhibit insulin aggregation. PSMα3 forms α-type amyloid-like fibrils to exert cytotoxic effects, and acts as a functional amyloid virulence determinant of Staphylococcus aureus. PSMα3 is applicable to research related to spondyloarthritis, rheumatoid arthritis, insulin-derived amyloidosis, and Staphylococcus aureus infection .

HY-N7122

Thymopentin	Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Phenols Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite
Thymopentin is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) .

HY-P1902A

Cardiotoxin Analog (CTX) IV (6-12) TFA 5+ Cited Publications	Structural Classification Pyrrole Alkaloids Animals Other Diseases Disease Research Fields Source Classification	Apoptosis
Cardiotoxin Analog (CTX) IV (6-12) TFA is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol). Cardiotoxin Analog (CTX) IV (6-12) TFA was discovered in the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) TFA is a chemically synthesized snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) TFA can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .

HY-N7404

Nε,Nε,Nε-Trimethyllysine chloride Ne-(Trimethyl)-L-lysine chloride; H-lys(Me)3-OH chloride	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA) .

HY-P0270

Magainin 2 Magainin II	Infection Structural Classification Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification	Bacterial Antibiotic Fungal
Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

HY-106302

Duramycin Moli1901; Lancovutide	Microorganisms Classification of Application Fields Inflammation/Immunology Disease Research Fields Source Classification	Bacterial
Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF) .

HY-P1482

α-Factor Mating Pheromone, yeast 2 Publications Verification Mating Factor α	Natural Products Microorganisms Classification of Application Fields Disease Research Fields Endocrinology Source Classification	Sex Pheromone
α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.

HY-P0261

Indolicidin	Infection Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification	Bacterial
Indolicidin is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils.

HY-P0004

Lysipressin 2 Publications Verification lysine vasopressin; [lys8]-Vasopressin	Monophenols Animals Classification of Application Fields Other Diseases Phenols Disease Research Fields Source Classification	Adenylate Cyclase Oxytocin Receptor
Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity .

HY-113089

Epsilon-(gamma-glutamyl)-lysine H-Glu(H-lys-OH)-OH; γ-Glu-ε-lys	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-P1189

Echistatin	Natural Products Animals Classification of Application Fields Inflammation/Immunology Disease Research Fields Source Classification	Integrin
Echistatin, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of α_IIbβ₃, α_vβ₃ and α₅β₁ .

HY-P0269

Magainin 1 Magainin I	Infection Structural Classification Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification	Bacterial Fungal Antibiotic
Magainin 1 (Magainin I) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria .

HY-P0263

Dermaseptin	Infection Structural Classification Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification	Bacterial Fungal Antibiotic
Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .

HY-P0279

Systemin	Natural Products other families Classification of Application Fields Other Diseases Solanum lycopersicum L. Solanaceae Plants Disease Research Fields Source Classification	Endogenous Metabolite
Systemin, an 18-amino acid polypeptide, has been isolated from tomato leaves that is a powerful inducer of over 15 defensive genes.

HY-P0240

Tuftsin 4 Publications Verification	Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
Tuftsin is a tetrapeptide. Tuftsin is a macrophage/microglial activator.

HY-126487A

*H-Arg-Lys-OH TFA*	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
H-Arg-Lys-OH TFA is a dipeptide formed from L-arginyl and L-lysine residues .

HY-P1280

Margatoxin 1 Publications Verification	Natural Products Animals Neurological Disease Disease Research Fields Source Classification	Potassium Channel
Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (K_d=11.7 pM). Margatoxin inhibits the Kv1.2 (K_d=6.4 pM) and Kv1.1 (K_d=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research .

HY-P1189A

Echistatin TFA	Natural Products Animals Classification of Application Fields Metabolic Disease Inflammation/Immunology Disease Research Fields Source Classification	Integrin
Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of α_IIbβ₃, α_vβ₃ and α₅β₁ .

HY-P0246

Mastoparan	Natural Products Animals Classification of Application Fields Metabolic Disease Disease Research Fields Source Classification	Endogenous Metabolite
Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.

HY-P0173B

Chlorotoxin TFA 2 Publications Verification	Natural Products Classification of Application Fields Animals Disease Research Fields Cancer Source Classification	Chloride Channel
Chlorotoxin TFA is a peptide isolated from the venom of the scorpion Leiurus quinquestriatus, acts as a chloride channel blocker . Anti-cancer activity .

HY-P0253

Xenopsin	Natural Products Animals Classification of Application Fields Metabolic Disease Disease Research Fields Source Classification	Neurotensin Receptor
Xenopsin, a neurotensin-like octapeptide from Xenopus laevis skin . Xenopsin is an inhibitor of Tetragastrin stimulated gastric acid secretion .

HY-P0285

Rabies Virus Glycoprotein 1 Publications Verification	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	RABV
Rabies Virus Glycoprotein is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells.

HY-113089A

Epsilon-(gamma-glutamyl)-lysine TFA H-Glu(H-lys-OH)-OH TFA; γ-Glu-ε-lys TFA	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-P0259

Xenin	Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
Xenin is a 25-amino acid peptide initially isolated from human gastric mucosa. Xenin is a gut hormone that can reduce food intake.

HY-P5714

Abaecin	Animals Ketones, Aldehydes, Acids Source Classification	Bacterial
Abaecin is an antibacterial response peptide. Abaecin shows specific activity against an Apidaecin-resistant Xanthomonas strain .

HY-P1346

APETx2	Natural Products Animals Source Classification	Sodium Channel
APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC₅₀ of 63 nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2 could reverses acid‐induced and inflammatory pain .

HY-N15829

*Cholyl-Lys-fluorescein sodium*	Structural Classification Lipid	Fluorescent Dye
Cholyl-Lys-fluorescein sodium is a fluorescein-labeled bile acid analog. Cholyl-Lys-fluorescein sodium mimics the physiological hepatobiliary properties of glycocholic acid. Cholyl-Lys-fluorescein sodium is efficiently taken up by the liver and rapidly excreted into bile in intact form in rats. Cholyl-Lys-fluorescein sodium can serve as a liver function assessment agent, bile salt transport probe, and liver-targeted carrier .

HY-P1866A

β-Endorphin, equine TFA 1 Publications Verification	Natural Products Endogenous metabolite Source Classification	Opioid Receptor
β-Endorphin, equine TFA is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors. β-Endorphin, equine TFA has analgesic properties .

HY-N7122A

Thymopentin acetate	Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Phenols Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) .

HY-113089AR

Epsilon-(gamma-glutamyl)-lysine TFA (Standard) H-Glu(H-lys-OH)-OH TFA (Standard); γ-Glu-ε-lys TFA (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
Epsilon-(gamma-glutamyl)-lysine (TFA) (Standard) is the analytical standard of Epsilon-(gamma-glutamyl)-lysine (TFA). This product is intended for research and analytical applications. Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-P0324

Parasin I	Infection Natural Products Classification of Application Fields Animals Disease Research Fields Source Classification	Bacterial
Parasin I is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity.

HY-P0302

HEX3 1 Publications Verification	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Others
HEX3 is a fragment of the adenoviral hexon. Hexon is the major capsid protein of adenovirion and is comprised of three identical polypeptide chains.

HY-P1482A

α-Factor Mating Pheromone, yeast TFA 2 Publications Verification Mating Factor α TFA	Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification Cancer	Sex Pheromone
α-Factor Mating Pheromone, yeast (TFA) is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor .

HY-P1841

Glucagon-Like Peptide (GLP) II, human	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Apoptosis
Glucagon-Like Peptide (GLP) II, human is a 33-amino acid peptide derived from the C-terminal of proglucagon and mainly produced by the intestinal L cells. Glucagon-Like Peptide (GLP) II, human stimulates intestinal mucosal growth and decreases apoptosis of enterocytes .

HY-126487

*H-Arg-Lys-OH*	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
H-Arg-Lys-OH is a dipeptide formed from L-arginyl and L-lysine residues .

HY-P0266A

*N-Acetyl-Ser-dAsp-Lys-Pro TFA* Ac-SdKP TFA	Cardiovascular Disease Structural Classification Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification	Angiotensin-converting Enzyme (ACE)
N-Acetyl-Ser-dAsp-Lys-Pro (TFA), an endogenous tetrapeptide secreted by bone marrow, is a specific substrate for the N-terminal site of ACE.

HY-N7404R

Nε,Nε,Nε-Trimethyllysine chloride (Standard) Ne-(Trimethyl)-L-lysine chloride (Standard); H-lys(Me)3-OH chloride (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA) .

HY-105088A

Pexiganan acetate MSI 78	Structural Classification Natural Products Animals Source Classification	Bacterial
Pexiganan (MSI 78) acetate is an orally active antimicrobial peptide with broad-spectrum bactericidal. Pexiganan TFA disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis. Pexiganan acetate can be used for the research of bacterial infection .

HY-P3065

Calcicludine	Natural Products Animals Source Classification	Calcium Channel
Calcicludine is a protein toxin from the venom of the green mamba that inhibits high-voltage-activated calcium channel, especially L-type calcium channel .

HY-P5708

Adenoregulin Dermaseptin b2	Animals Ketones, Aldehydes, Acids Source Classification	Antibiotic Fungal Bacterial
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .

HY-P3055

Dendrotoxin-I DTX-I	Animals Cyclopeptides Animal Venoms Source Classification	Potassium Channel
Dendrotoxin-I (DTX-I) is a potent K ⁺ channels blocker with IC₅₀s of 0.13-50 nM for voltage-gated potassium channel subunits K_V1.1, K_V1.2 and K_V1.6, respectively. Dendrotoxin-I, a neurotoxin, has the potential for cancer research .

HY-P1866

β-Endorphin, equine	Natural Products Endogenous metabolite Source Classification	Opioid Receptor
β-Endorphin, equine is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors . Analgesic properties .

Cat. No.	Product Name	Chemical Structure

HY-79128S1

*Fmoc-L-Lys* (Boc)-OH-13C6,15N2**
Fmoc-L-Lys (Boc)-OH- ¹³C₆, ¹⁵N₂ is a ¹⁵N-labeled and ¹³C-labled Fmoc-L-Lys (Boc)-OH (HY-79128). Fmoc-L-Lys (Boc)-OH is a lysine derivative .

HY-N7404S

Nε,Nε,Nε-Trimethyllysine-d9 chloride
Nε,Nε,Nε-Trimethyllysine-d₉ (chloride) is the deuterium labeled Nε,Nε,Nε-Trimethyllysine (chloride) . Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA) .

HY-176347S

*Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2*
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

HY-176258S

*Growth Hormone 22, Arg-13C6,15N4, Lys-13C6,15N2*

HY-P1363S

β-Amyloid-15N (1-42), human TFA
β-Amyloid- ¹⁵N (1-42), human (TFA) is the ¹⁵N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .

HY-P1624S1

Teduglutide-Leu(13C6,15N) sodium

Teduglutide-Leu( ¹³C₆, ¹⁵N) (ALX-0600-Leu( ¹³C₆, ¹⁵N)) sodium is the ¹³C- and ¹⁵N-labeled Teduglutide (HY-P1624). Teduglutide (ALX-0600) is an analog of human glucagon like peptide-2 (GLP-2). Teduglutide can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis .

HY-P3207S

*DLPLTFGGGT-Lys-13C6,15N2 TFA*
DLPLTFGGGT-Lys-13C6,15N2 (TFA) is a deuterated labeled DLPLTFGGGTK .

HY-176309S

*Tau 441, Arg-13C6,15N4, Lys-13C6,15N2*
Tau 441, Arg- ¹³C₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Tau 441.

HY-13443S

Exendin-4 (Leu-13C6,15N) TFA
Exendin-4 (Leu- ¹³C₆, ¹⁵N) (Exenatide (Leu- ¹³C₆, ¹⁵N)) TFA is the ¹³C- and ¹⁵N-labeled Exendin-4 TFA (HY-13443). Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC₅₀ of 3.22 nM .

HY-P0265AS

β-Amyloid-15N (1-40) TFA
β-Amyloid- ¹⁵N (1-40) (TFA) is the ¹⁵N-labledβ-Amyloid (1-40) (TFA). β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease .

HY-P1363S1

β-Amyloid (1-42), human, Ala(13C3,15N) TFA

β-Amyloid (1-42), human, Ala( ¹³C₃, ¹⁵N) TFA is the ¹³C and ¹⁵N-labeled β-Amyloid (1-42), human (HY-P1363A). β-Amyloid (1-42) (Amyloid β-peptide (1-42)), human, a 42-amino acid peptide that has not been treated with HFIP, is a brain-penetrant amyloid protein fragment, which can be used in research on Alzheimer's disease and Down’s syndrome. β-Amyloid (1-42), human remaining as a monomer exhibits antioxidant and neuroprotective effects. β-Amyloid (1-42), human, after being monomericized by HFIP and dissolved in DMSO to form the stock solution, on the one hand, can form soluble oligomers (AβOs) when incubated at 4 °C, which have synaptic toxicity and neurotoxicity; on the other hand, it can be incubated at 37 °C to form insoluble fibrils, with lower neurotoxicity, and participating in the oxidative damage process. Aβ42 oligomers bind to various neuronal surface receptors (such as PrPc, mGluR5, NMDA receptors, etc.), triggering oxidative stress, calcium homeostasis imbalance, and synaptic toxicity via activating downstream signaling pathways, leading to neuronal dysfunction and death .

HY-P60579S

{pGlu}-P-{Leu-13C6,15N}-PDCCRQKTCSCR-{Leu-13C6,15N}-YELLHGAGNHAAGILTL-NH2 TFA
{pGlu}-P-{Leu- ¹³C₆, ¹⁵N}-PDCCRQKTCSCR-{Leu- ¹³C₆, ¹⁵N}-YELLHGAGNHAAGILTL-NH2 TFA is the ¹³C- and ¹⁵N labeled {pGlu}-P-{Leu}-PDCCRQKTCSCR-{Leu}-YELLHGAGNHAAGILTL-NH2 TFA.

HY-106224AS1

Orexin A-13C18,15N3 (human, rat, mouse) TFA

Orexin A- ¹³C₁₈, ¹⁵N₃ (human, rat, mouse) ((Hypocretin-1- ¹³C₁₈, ¹⁵N₃ (human, rat, mouse)) TFA is the ¹³C- and ¹⁵N-labeled Orexin A (human, rat, mouse) (HY-106224). Orexin A (human, rat, mouse) (Hypocretin-1 (human, rat, mouse)), a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A (human, rat, mouse) binds and activates two types of G protein-coupled receptors, the orexin-1 receptor (OX1R) and the orexin-2 receptor (OX2R). Orexin A (human, rat, mouse) has a role in the regulation of feeding behavior. Orexin A (human, rat, mouse) is an effective anti-nociceptive and anti-hyperalgesic agent in mice and rats .

HY-W007750S

*H-Lys(Z)-OH-d3*
H-Lys(Z)-OH-d₃ is the deuterium labeled H-Lys(Z)-OH.

HY-79128S

*Fmoc-L-Lys* (Boc)-OH-15N2**
Fmoc-L-Lys (Boc)-OH- ¹⁵N₂ is a ¹⁵N-labeled Fmoc-L-Lys (Boc)-OH (HY-79128). Fmoc-L-Lys (Boc)-OH is a lysine derivative .

HY-163422S

*PHSHPALTPEQK-(Lys-13C6,15N2)*
PHSHPALTPEQK-(Lys- ¹³C₆, ¹⁵N₂) is ¹³C and ¹⁵N labeled PHSHPALTPEQK-(Lys).

HY-163424S

*SSVFVADPK-(Lys-13C6,15N2)*
SSVFVADPK-(Lys- ¹³C₆, ¹⁵N₂) is ¹³C and ¹⁵N labeled SSVFVADPK-(Lys).

HY-79128S2

*Fmoc-L-Lys* (Boc)-OH-13C**
Fmoc-L-Lys (Boc)-OH- ¹³C (Fmoc-L-Lys(Boc)-OH- ¹³C) is ¹³C labeled Fmoc-L-Lys (Boc)-OH. Fmoc-L-Lys (Boc)-OH is a lysine derivative .

HY-163425S

*AILNYVANK-(Lys-13C6,15N2)*
AILNYVANK-(Lys- ¹³C₆, ¹⁵N₂) is ¹³C and ¹⁵N labeled AILNYVANK-(Lys) .

HY-163427S

*FNLEALVTHTLPFEK-(Lys-13C6,15N2)*
FNLEALVTHTLPFEK-(Lys- ¹³C₆, ¹⁵N₂) is ¹³C and ¹⁵N labeled FNLEALVTHTLPFEK-(Lys) .

HY-156345S1

*LPFTFGQGTK-(Lys-13C6,15N2) TFA*
LPFTFGQGTK-(Lys- ¹³C₆, ¹⁵N₂) TFA is the peptide containing ¹³C- and ¹⁵N-labeled Lys.

HY-173085S

*TPPSSGEPPK-(Lys-13C6,15N2) TFA*
TPPSSGEPPK-(Lys- ¹³C₆, ¹⁵N₂) TFA is the ¹³C- and ¹⁵N-labeled TPPSSGEPPK-(Lys) TFA.

HY-156343S1

*SNNYATHYAESVK-(Lys-13C6,15N2) TFA*
SNNYATHYAESVK-(Lys- ¹³C₆, ¹⁵N₂) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Lys.

HY-P11536S

*STEDTAEYSPF-(Lys-13C6,15N2) TFA*
STEDTAEYSPF-(Lys- ¹³C₆, ¹⁵N₂) TFA is the ¹³C- and ¹⁵N-labeled STEDTAEYSPF.

HY-P11534S

*DNYLGGTSTISDNA-(Lys-13C6,15N2) TFA*
DNYLGGTSTISDNA-(Lys- ¹³C₆, ¹⁵N₂) TFA is the ¹³C- and ¹⁵N-labeled DNYLGGTSTISDNA.

HY-176306S

*Synuclein alpha, Lys-13C6,15N2*
Synuclein alpha, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Synuclein alpha.

HY-P5190S1

*RQIK-(Lys-fructosyl)-QTA-(Leu-13C6,15N)-VE TFA*
RQIK-(Lys-fructosyl)-QTA-(Leu- ¹³C₆, ¹⁵N)-VE TFA is the ¹³C and ¹⁵N labeled compound .

HY-176304S

*Neurofilament, Arg-13C6,15N4, Lys-13C6,15N2*
Neurofilament, Arg- ¹³C₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Neurofilament.

HY-176314S

*Clusterin protein, Arg-13C6,15N4, Lys-13C6,15N2*
Clusterin protein, Arg- ¹³C₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Clusterin protein.

HY-176358S

*KRAS 2B G12C mutant, Arg-13C6,15N4, Lys-13C6,15N2*
KRAS 2B G12C mutant, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled KRAS 2B G12C mutant.

HY-176359S

*KRAS 2B G12D mutant, Arg-13C6,15N4, Lys-13C6,15N2*
KRAS 2B G12D mutant, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled KRAS 2B G12D mutant.

HY-176354S

*KRAS 2B G12V mutant, Arg-13C6,15N4, Lys-13C6,15N2*
KRAS 2B G12V mutant, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled KRAS 2B G12V mutant.

HY-W286743S

CML-d4
CML-d₄ is the deuterium labeled Fmoc-L-Lys (Boc)-OH .

HY-P0119S

Lixisenatide (Leu-13C6,15N) TFA

Lixisenatide (Leu- ¹³C₆, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled Lixisenatide (HY-P0119). Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide can be used for the researches of inflammation, metabolic disease, neurological disease and cardiovascular disease, such as rheumatoid arthritis, diabetes, Alzheimer's disease and atherosclerosis .

HY-P10285S

d-KLA Peptide-d30

d-KLA Peptide (D-(KLAKLAK)2)-d₃₀ is the deuterium labeled d-KLA Peptide (HY-P10285). d-KLA Peptide, KLA peptide (HY-P5345) isomer, is a pro-apoptosis peptide. d-KLA Peptide can specifically target mitochondria and induce apoptosis by destroying the mitochondrial membrane. d-KLA Peptide increases caspase 3/7 activity, exerts proapoptotic activity and enhances antitumor efficacy in mouse melanoma models .

HY-159191S

VQPGQN(Phe-13C9,15N)HMFTKEKLEEVIKDI TFA
VQPGQN(Phe- ¹³C9, ¹⁵N)HMFTKEKLEEVIKDI (TFA) is the ¹³C and ¹⁵N labeled isotope of VQPGQN-HMFTKEKLEEVIKDI (TFA) .

HY-158992S

SP-(Val-13C5,15N)-EKNQ-(Leu-13C6,15N)-TIDFINIVKDPVPHNEYKT TFA
SP-(Val- ¹³C₅, ¹⁵)-EKNQ-(Leu- ¹³C₆, ¹⁵)-TIDFINIVKDPVPHNEYKT TFA is a ¹³C- and ¹⁵N-labeled peptide containing ¹³C₅, ¹⁵N-labeled valine (Val) and ¹³C₆, ¹⁵N-labeled leucine (Leu).

HY-P10324

TAT-p16
TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .

HY-P0090S

Calcitonin-13C6,15N4 (salmon) TFA
Calcitonin- ¹³C₆, ¹⁵N₄ (salmon) (Salmon calcitonin- ¹³C₆, ¹⁵N₄) TFA is ¹³C and ¹⁵N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption .

HY-P6696S

β-CL, Ala(13C3,15N) TFA
β-CL, Ala(sup>13C₃, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled β-CL TFA.

HY-P1033S

[Pyr1]-Apelin-13, Gly(15N) TFA
Pyr1]-Apelin-13, Gly(15N) TFA is a Gly ¹⁵N labeled [Pyr1]-Apelin-13. [Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor agonist .

HY-P3448S1

Certepetide-13C2,15N

Certepetide- ¹³C₂, ¹⁵N (CEND-1- ¹³C₂, ¹⁵N) is the ¹³C- and ¹⁵N-labeled Certepetide (HY-P3448). Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors .

HY-176176S

MDEKMLVLWVVALS(Gly-13C2,15N)IST
MDEKMLVLWVVALS(Gly- ¹³C₂, ¹⁵N)IST is the ¹³C- and ¹⁵N-labeled MDEKMLVLWVVALSIST.

HY-P2625S

GLP-2(3-33) (Leu-13C6,15N)
GLP-2(3-33) (Leu- ¹³C₆, ¹⁵N) is ¹³C and ¹⁵N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC₅₀=5.8 nM).

HY-P2625S1

GLP-2(3-33) (Leu-13C6,15N) TFA
GLP-2(3-33) (Leu- ¹³C₆, ¹⁵N) TFA is ¹³C and ¹⁵N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC₅₀=5.8 nM).

HY-P1142S

GLP-2(rat) (Ala-13C3,15N)
GLP-2(rat) (Ala- ¹³C3, ¹⁵N) is ¹³C and ¹⁵N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).

HY-P1624S

Teduglutide-Ala(13C3,15N) sodium

Teduglutide-Ala( ¹³C₃, ¹⁵N) (ALX-0600-Ala( ¹³C₃, ¹⁵N)) sodium is the ¹³C- and ¹⁵N-labeled Teduglutide (HY-P1624). Teduglutide (ALX-0600) is an analog of human glucagon like peptide-2 (GLP-2). Teduglutide can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis .

HY-P1142S1

GLP-2(rat) (Ala-13C3,15N) TFA
GLP-2(rat) (Ala- ¹³C3, ¹⁵N) TFA is ¹³C and ¹⁵N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).

HY-P0058S

Pramlintide-(Ala-13C3,15N)
Pramlintide-(Ala- ¹³C₃, ¹⁵N) is the ¹³C- and ¹⁵N-labeled Pramlintide. Pramlintide is a polypeptide analogue of human amylin. Pramlintide, an antidiabetic agent, is antineoplastic in colorectal cancer .

HY-173088S

*IPAK(pT)PPAPK-(Lys-13C6,15N2) TFA*
IPAK(pT)PPAPK-(Lys- ¹³C₆, ¹⁵N₂) TFA is the ¹³C- and ¹⁵N-labeled IPAK(pT)PPAPK-(Lys) TFA.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks