MICAL1 - microtubule associated monooxygenase, calponin and LIM domain containing 1 Gene

Also Known as MICAL; NICAL; MICAL-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64780

About MICAL1

Cytogenetic location: 6q21 Genomic coordinates (GRCh38): 6:109,444,062-109,465,968 (from NCBI)

This gene has 8 transcripts (splice variants), 198 orthologues, 36 paralogues and is associated with 1 phenotype. Ubiquitous expression in bone marrow (RPKM 31.4), lymph node (RPKM 25.8) and 23 other tissues.

Summary

This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

MICAL1 Products (3)

mRNA Protein Name
NM_001159291.2 NP_001152763.1 [F-actin]-monooxygenase MICAL1 isoform 2
NM_001286613.2 NP_001273542.1 [F-actin]-monooxygenase MICAL1 isoform 3
NM_022765.4 NP_073602.3 [F-actin]-monooxygenase MICAL1 isoform 1

MICAL1 Protein Structure

FAD_binding_3

FAD_binding_3: FAD binding domain (85 - 122)

CH

CH: Calponin homology (CH) domain (512 - 610)

LIM

LIM: LIM domain (697 - 750)

DUF3585

DUF3585: Protein of unknown function (DUF3585) (926 - 1059)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1067 a.a.
Protein Preferred Names Protein Names

[F-actin]-monooxygenase MICAL1

  • NEDD9-interacting protein with calponin homology and LIM domains

Related Diseases

Diseases Alias
Epilepsy, Familial Temporal Lobe, 1

  • ETL1

  • Adpeaf

  • Adlte

  • Epilepsy, Partial, With Auditory Features

  • Autosomal Dominant Partial Epilepsy With Auditory Features

  • Epilepsy, Lateral Temporal Lobe, Autosomal Dominant

  • Familial Temporal Lobe Epilepsy 1

  • Partial Epilepsy With Auditory Features

  • Autosomal Dominant Lateral Temporal Lobe Epilepsy

  • Lateral Temporal Lobe Epilepsy Autosomal Dominant

  • Epilepsy, Temporal Lobe, Familial, Type 1
Epilepsy, Familial Temporal Lobe, 7

  • Familial Temporal Lobe Epilepsy 7

  • ETL7

  • Epilepsy, Temporal Lobe, Familial, Type 7
Cerebral Amyloid Angiopathy, Itm2b-Related, 1

  • Dementia, Familial British

  • Fbd

  • Presenile Dementia With Spastic Ataxia

  • Familial British Dementia

  • Abri Amyloidosis

  • Cerebral Amyloid Angiopathy, British Type

  • Itm2b-Related Cerebral Amyloid Angiopathy 1

  • Familial Dementia, British Type

  • Cerebral Amyloid Angiopathy, Itm2b-Related 1

  • CAA-ITM2B1

  • Cerebral Amyloid Angiopathy British Type

  • Dementia, Familial, British
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (31)
Cat. No. Nom du produit Effect
Pureté Rare Diseases
HY-B2176 ATP 99.88% Unkown
HY-13757 Tamoxifen Citrate 99.88% Yes
HY-12678 Entrectinib 99.26% Yes
HY-109506 DPPC 99.91% Unkown
HY-B1192 Estradiol benzoate Agonist 99.90% Unkown
HY-109044 Tapinarof Agonist 99.95% Unkown
HY-B0448 Phenytoin Inhibitor 99.95% Yes
HY-B1005 8-Hydroxyquinoline Inhibitor 99.99% Unkown
HY-B0892 Benzyl alcohol 99.99% Unkown
HY-B0693 Ranitidine Antagonist 99.9% Yes
HY-B0448A Phenytoin sodium Inhibitor 99.78% Yes
HY-B0111 Drospirenone Agonist 99.95% Unkown
HY-124290 Carotegrast methyl Antagonist 99.24% Unkown
HY-B0344 Methscopolamine bromide Inhibitor 99.81% Unkown
HY-B1198 Piperonyl butoxide Inhibitor 98.0% Unkown
HY-B0281A Ranitidine hydrochloride Antagonist 99.86% Yes
HY-B0417A Lincomycin hydrochloride Inhibitor 99.59% Unkown
HY-B1350A Fusidic acid sodium salt Inhibitor 99.64% Yes
HY-B1358 Lincomycin hydrochloride monohydrate Inhibitor 99.74% Unkown
HY-B1640R Ethacrynic acid (Standard) Inhibitor 98.78% Unkown
HY-117660 Lincomycin Inhibitor 99.82% Unkown
HY-13859 Clevudine Inhibitor 99.84% Unkown
HY-B1268 Docusate Sodium Inhibitor 98.0% Unkown
HY-P0009 Cetrorelix Antagonist 99.71% Yes
HY-12752A Alimemazine hemitartrate 99.49% Unkown
HY-B0921 Succinylsulfathiazole Inhibitor 99.75% Unkown
HY-B0693A Ranitidine bismuth citrate / Unkown
HY-B1198R Piperonyl butoxide (Standard) Inhibitor / Unkown
HY-B1640A Ethacrynic acid sodium Inhibitor / Unkown
HY-133171A (S)-Norfluoxetine Inhibitor / Unkown
HY-B0430B (±)-Pantothenic acid / Unkown
Inhibitory Antibodies (2)
Cat. No. Nom du produit Effect
Pureté Rare Diseases
HY-P9944 Palivizumab Inhibitor 99.63% Unkown
HY-P99797 Pabinafusp alfa 98.89% Unkown

Clinical Phase

Bioactive Molecules (30)
Cat. No. Nom du produit Effect
Pureté Phase
HY-B1946 Dimethoate 99.91% Phase 4
HY-N6869 Dehydroabietic acid 98.52% Phase 4
HY-163885 SSZ Inhibitor 98.13% Phase 4
HY-124290A Carotegrast methyl hydrochloride Antagonist / Phase 4
HY-10484 Pevonedistat hydrochloride 99.19% Phase 3
HY-123475 Sisunatovir Inhibitor 99.40% Phase 3
HY-145721 Mongersen Inhibitor 98.57% Phase 3
HY-106837 Israpafant Antagonist / Phase 3
HY-138842 DDN Activator / Phase 3
HY-176127 JX10 Inhibitor / Phase 3
HY-100442 Paquinimod Inhibitor 99.90% Phase 2
HY-10367 Canertinib Inhibitor 99.74% Phase 2
HY-141523 Vociprotafib Inhibitor 99.70% Phase 2
HY-14530 Pelitrexol 98.07% Phase 2
HY-129239 Farudodstat 99.68% Phase 2
HY-160023 Elisrasib 99.68% Phase 2
HY-103400 8-Chloroadenosine 99.75% Phase 2
HY-18099 S1RA Antagonist 98.96% Phase 2
HY-120083 Rodatristat Inhibitor 98.41% Phase 2
HY-137440A Firazorexton hydrate 99.94% Phase 2
HY-106887 SCH 32615 99.68% Phase 2
HY-168739 Topoisomerase I inhibitor 17 / Phase 2
HY-116175 BIBB 515 99.56% Phase 1
HY-125639 (rac)-AR-13503 Inhibitor 99.08% Phase 1
HY-P10032 NN1177 99.54% Phase 1
HY-115681 (2R/S)-6-PNG Inhibitor 99.96% Phase 1
HY-111792 GSK1795091 Agonist 94.48% Phase 1
HY-106925 Cetefloxacin Inhibitor / Phase 1
HY-117630 RB-6145 / Phase 1
HY-101699A AMG-076 Antagonist / Phase 1
Inhibitory Antibodies (3)
Cat. No. Nom du produit Effect
Pureté Phase
HY-P9983 Lintuzumab Inhibitor 98.09% Phase 3
HY-P99744 Modakafusp alfa Inhibitor 96.22% Phase 2
HY-P991961 REGN4659 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (539)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-70062 Pevonedistat 99.98% Unkown
HY-14452 Fatostatin Inhibitor 99.85% Unkown
HY-N0219 Bicuculline Antagonist 99.98% Unkown
HY-134901 WM-3835 99.78% Unkown
HY-160769 NIBR-LTSi 99.97% Unkown
HY-131042 NNMTi Inhibitor 99.70% Unkown
HY-110171 iMDK Inhibitor 99.35% Unkown
HY-113354 Anserine 99.85% Unkown
HY-160818 MC3138 Activator 99.92% Unkown
HY-N2342 Procyanidin C1 Inducer 99.54% Unkown
HY-120912 Gingerenone A Activator 99.95% Unkown
HY-103124 DOI hydrochloride Agonist 99.61% Unkown
HY-14452A Fatostatin hydrobromide Inhibitor 99.52% Unkown
HY-143228 SH-42 Inhibitor 99.87% Unkown
HY-103157 PD146176 99.59% Unkown
HY-156856 FL118-14-Propanol 99.56% Unkown
HY-135747 Gut restricted-7 Inhibitor 99.54% Unkown
HY-126255 SBI-797812 Activator 99.88% Unkown
HY-P1925A GO-203 TFA 98.39% Unkown
HY-137207 MK-28 Activator 99.88% Unkown
HY-103017A JH-X-119-01 Inhibitor 99.65% Unkown
HY-114169 WRG-28 Inhibitor 99.76% Unkown
HY-131181 LEI-401 Inhibitor 99.73% Unkown
HY-161834 RG100204 Inhibitor 99.50% Unkown
HY-113365 Cholestenone 99.95% Unkown
HY-125474 Carrageenan Inhibitor / Unkown
HY-108559 L-161982 Inhibitor 99.33% Unkown
HY-117427 D5D-IN-326 99.90% Unkown
HY-P1587 IRBP (1-20), human 99.58% Unkown
HY-156117 LB244 Inhibitor 98.45% Unkown
HY-134494 MS48107 99.90% Unkown
HY-124284 Hexamethylene bisacetamide 99.56% Unkown
HY-111754 DMX-5804 Inhibitor 99.64% Unkown
HY-W010042 L-Glucose 99.90% Unkown
HY-110171A iMDK quarterhydrate Inhibitor 99.37% Unkown
HY-145721A Mongersen sodium 99.61% Unkown
HY-N8522 9,10-Dihydroxystearic acid 98.0% Unkown
HY-P1290A PKA Inhibitor Fragment (6-22) amide TFA Inhibitor 99.77% Unkown
HY-P1136C TAT-Gap19 TFA 99.41% Unkown
HY-103111 MMPIP hydrochloride Antagonist 98.31% Unkown
HY-101404A L-Homocysteine thiolactone hydrochloride 99.99% Unkown
HY-147323 Ferulic acid 4-O-sulfate 98.86% Unkown
HY-110190 VU0422288 Modulator 99.94% Unkown
HY-N1388 Tussilagone 99.52% Unkown
HY-P1136B TAT-Gap19 99.60% Unkown
HY-120597 SAK3 Activator 99.80% Unkown
HY-121675 2-Bromo-LSD 97.26% Unkown
HY-B0708 β-Estradiol 17-acetate Agonist 99.93% Unkown
HY-W013411A Locostatin 99.88% Unkown
HY-129297 CMPF 99.64% Unkown
HY-19350 BML-210 98.04% Unkown
HY-B1002 Oxolinic acid Inhibitor 98.97% Unkown
HY-W015635 Diallyl disulfide Inhibitor 99.8% Unkown
HY-B2176I ATP disodium salt, 100 mM Solution, PCR Grade / Unkown
HY-101029 MBM-55 99.94% Unkown
HY-127034 Antipain dihydrochloride Inhibitor 99.9% Unkown
HY-N2189 Swertisin 99.54% Unkown
HY-114918 MS438 Agonist 99.85% Unkown
HY-125130 Hesperetin 7-O-glucoside Inhibitor 99.38% Unkown
HY-171034 PQA-18 Inhibitor 99.62% Unkown
HY-103017 JH-X-119-01 hydrochloride Inhibitor 99.14% Unkown
HY-10367A Canertinib dihydrochloride Inhibitor 99.68% Unkown
HY-161305 SE-7552 Inhibitor 99.48% Unkown
HY-119347 Cirsilineol Inhibitor 98.0% Unkown
HY-113412A 3-Methylhistamine dihydrochloride 99.80% Unkown
HY-145313 TTBK1-IN-2 Inhibitor 99.91% Unkown
HY-15805 KIN-8194 Inhibitor 99.26% Unkown
HY-N5106 (E)-Flavokawain A Inducer 99.53% Unkown
HY-W018171 3,5,6-Trichloro-2-pyridinol 99.85% Unkown
HY-156856S FL118-14-Propanol-d5 97.86% Unkown
HY-155157 PF-07247685 98.66% Unkown
HY-21196A Potassium perfluorohexanesulfonate 98.0% Unkown
HY-N7271 Solanidine 99.90% Unkown
HY-103290 R715 Antagonist 99.67% Unkown
HY-N1109 Uvaol Inducer 99.20% Unkown
HY-P2203 SAHM1 Inhibitor 96.48% Unkown
HY-116538 (10E,12Z)-Octadeca-10,12-dienoic acid Activator 99.10% Unkown
HY-N10991 Crocetin dialdehyde 99.75% Unkown
HY-111358 TLR7 agonist 1 Agonist 98.19% Unkown
HY-101139A Xanthine amine congener hydrochloride Antagonist 98.03% Unkown
HY-107527 Org 25543 hydrochloride Inhibitor 99.93% Unkown
HY-137440 Firazorexton 99.56% Unkown
HY-163087 PT-91 Agonist 98.78% Unkown
HY-B2046 Simazine 99.44% Unkown
HY-N0506 Rosarin 99.96% Unkown
HY-N6962 α-Spinasterol 99.90% Unkown
HY-164546 WB436B 99.93% Unkown
HY-B0448S Phenytoin-d10 Inhibitor 99.50% Unkown
HY-108497 L-803087 Agonist 99.66% Unkown
HY-Y0850U6 PVA (Mw 205000) / Unkown
HY-N2736 3′,4′,7-Trihydroxyflavone Inhibitor 99.04% Unkown
HY-N0901A Corynoxine B Inhibitor 99.76% Unkown
HY-116818 Crebinostat Inhibitor 98.83% Unkown
HY-120589 VU0360172 Agonist 98.07% Unkown
HY-121035 7BIO Inhibitor 99.20% Unkown
HY-12242 GBR 12935 dihydrochloride Inhibitor 99.80% Unkown
HY-143793 RBP4 inhibitor 1 Inhibitor 99.49% Unkown
HY-21193 Perfluoropentanoic acid 98.0% Unkown
HY-P1259A PR-39 TFA Inhibitor 99.89% Unkown
HY-Y1809 1-Hydroxyoctadecane 99.65% Unkown
HY-132302 Hu7691 Inhibitor 99.91% Unkown
HY-147222 SAE-14 Antagonist 98.60% Unkown
HY-155478 Androgen receptor-IN-6 Inhibitor 98.26% Unkown
HY-160237 HYL001 Inhibitor 99.94% Unkown
HY-164495 Sob-AM2 Agonist 98.5% Unkown
HY-P3102 GLP-1(32-36)amide 98.44% Unkown
HY-148506 5'-ODMT cEt m5U Phosphoramidite (Amidite) 99.76% Unkown
HY-149449 Poly-L-γ-glutamic acid sodium / Unkown
HY-120000 MS402 Inhibitor 98.36% Unkown
HY-145774 PD-1/PD-L1-IN-23 Inhibitor 99.98% Unkown
HY-118282 mPGES1-IN-7 Inhibitor 99.78% Unkown
HY-12678S1 Entrectinib-d8 99.82% Unkown
HY-136182 YM-244769 dihydrochloride Inhibitor 98.57% Unkown
HY-136182A YM-244769 Inhibitor 99.22% Unkown
HY-139659 ARD-61 99.57% Unkown
HY-156374 D359-0396 Inhibitor 99.98% Unkown
HY-161671 GAT2711 Agonist 98.00% Unkown
HY-162387 UK4b Inhibitor 96.17% Unkown
HY-162428 PTPN2/1-IN-3 Inhibitor 99.89% Unkown
HY-163782 SMIP-031 98.60% Unkown
HY-N2411 Geissoschizine methyl ether Agonist 99.97% Unkown
HY-N3522 Platycoside E Inhibitor 99.40% Unkown
HY-P1302 Orphanin FQ(1-11) Agonist 99.83% Unkown
HY-W248594 IR 813 tosylate 98.52% Unkown
HY-W674241 4-Ethylphenyl sulfate Inducer / Unkown
HY-113354S Anserine-d4 99.38% Unkown
HY-B1946S Dimethoate-d6 99.86% Unkown
HY-P5489 IGRP(206-214) Agonist 96.63% Unkown
HY-148100 Emapticap pegol Inhibitor 91.38% Unkown
HY-123475A Sisunatovir hydrochloride Inhibitor 98.05% Unkown
HY-100935 Cimaterol Agonist 99.13% Unkown
HY-118824A N-Feruloylserotonin Inhibitor 99.93% Unkown
HY-121852 SCH 336 Agonist 98.63% Unkown
HY-143312E (S)-V-0219 hydrochloride Modulator 99.71% Unkown
HY-144899 ASR-490 Inhibitor 99.20% Unkown
HY-162866 CXM102 Activator 99.36% Unkown
HY-D0887 Disodium 5'-inosinate 99.74% Unkown
HY-N1503 Methyl deacetylasperulosidate 98.49% Unkown
HY-N7026 Celosin I 99.91% Unkown
HY-172930 PVTX-405 97.07% Unkown
HY-126193 JS-K 99.59% Unkown
HY-126367 Light green SF yellowish 75.0% Unkown
HY-139973 OAB-14 99.21% Unkown
HY-163729 I-BET787 Inhibitor 99.88% Unkown
HY-164397 XMU-MP-5 99.00% Unkown
HY-173313 Ferroptosis-IN-19 Inhibitor 98.92% Unkown
HY-174400 SGLT2-IN-2 Inhibitor 99.57% Unkown
HY-N6579 Arvenin I 89.41% Unkown
HY-N9173 Cupressuflavone 99.32% Unkown
HY-P10032A NN1177 TFA 99.22% Unkown
HY-P10816 PACE4 Inhibitory peptide C23 99.40% Unkown
HY-114853 BVT.13 Agonist 98.44% Unkown
HY-114992 2-Propyl-2-pentenoic acid 95.0% Unkown
HY-160554 C12-113 98.67% Unkown
HY-B1870 Metaldehyde 98.0% Unkown
HY-136522 S2116 98.05% Unkown
HY-B1198S Piperonyl butoxide-d9 Inhibitor 98.68% Unkown
HY-100442S1 Paquinimod-d5-1 Inhibitor 98.19% Unkown
HY-106947 SY-640 99.77% Unkown
HY-107503 MMPIP Antagonist 99.38% Unkown
HY-117081 C30(ω-hydroxy) Ceramide (d18:1/30:0) 99.46% Unkown
HY-121675A 2-Bromo-LSD D-Tartrate 99.91% Unkown
HY-124609 CAD031 99.39% Unkown
HY-129087 BC-​1258 Inducer 99.85% Unkown
HY-130136A TMPRSS6-IN-1 TFA Inhibitor / Unkown
HY-14866 Raseglurant Modulator 99.65% Unkown
HY-155156 PF-07238025 Inhibitor 99.46% Unkown
HY-156277 SP4f Activator 99.77% Unkown
HY-156842 MCAAD-3 98.19% Unkown
HY-157014 TPT-004 Inhibitor 99.90% Unkown
HY-161853 TX-2552 Inhibitor 99.69% Unkown
HY-162702 AZ'3137 Degrader 99.90% Unkown
HY-169240 MX69-102 Activator 99.44% Unkown
HY-173267 CES2A-IN-2 Inhibitor 99.16% Unkown
HY-19015 Probimane Inhibitor 99.91% Unkown
HY-N9794 Isoboldine 95.0% Unkown
HY-P1949A Cyclic MKEY TFA 98.47% Unkown
HY-W009688 Dibutyl maleate 99.19% Unkown
HY-W012837 Benzylmethyl ether Inhibitor 98.70% Unkown
HY-20874 Deschlorodemethyldiazepam 99.80% Unkown
HY-W013755 Dioctyl phthalate 99.40% Unkown
HY-101030A MBM-17S / Unkown
HY-120872 AJS1669 free acid Activator 99.15% Unkown
HY-153262 (7R)-Elisrasib Inhibitor 99.52% Unkown
HY-103177 PSB-10 hydrochloride Inhibitor / Unkown
HY-103327 MJ15 Antagonist / Unkown
HY-107504 VU0360172 hydrochloride Agonist 98.94% Unkown
HY-107659 YM-244769 hydrochloride Inhibitor 98.09% Unkown
HY-112636 Astrophloxine Inhibitor 98.34% Unkown
HY-113878 12-OAHSA 99.0% Unkown
HY-120514 JNc-440 98.04% Unkown
HY-121271 Kadsurin 99.38% Unkown
HY-122817 FR900098 sodium Inhibitor 99.77% Unkown
HY-126152 Chlorthiamid 95.69% Unkown
HY-12678S Entrectinib-d4 Inhibitor / Unkown
HY-130136 TMPRSS6-IN-1 Inhibitor / Unkown
HY-151876 Glucocorticoid receptor modulator 1 99.79% Unkown
HY-156276 SP4e Activator 99.72% Unkown
HY-156936 RCB-02-4-8 99.3% Unkown
HY-159972 PKR1 antagonist 1 Antagonist / Unkown
HY-160550 DPM-1003 Inhibitor / Unkown
HY-161901 BC-1293 Inhibitor 98.40% Unkown
HY-162765 TRPV4-IN-5 Inhibitor 98.77% Unkown
HY-167862A UCM-05194 ammonium Agonist / Unkown
HY-179474 TSI-13-57 Inhibitor 98.73% Unkown
HY-18164 TASP0277308 Antagonist 99.00% Unkown
HY-B1002R Oxolinic acid (Standard) Inhibitor 97.60% Unkown
HY-D1056A5 Lipopolysaccharides, from E. coli K-235 Activator / Unkown
HY-D1065 NIR-H2O2 / Unkown
HY-N3204 Neoechinulin A Inhibitor 98.0% Unkown
HY-N5097 13-Oxo-9E,11E-octadecadienoic acid Activator / Unkown
HY-N7514 Strictosidinic acid Inhibitor 95% Unkown
HY-P11060 MC38 SLP Adpgk 97.52% Unkown
HY-P5117 TAT-CIRP Inhibitor 98.32% Unkown
HY-P5890A YVAD-CHO TFA Inhibitor 98.48% Unkown
HY-W013411 (E/Z)-Locostatin Control 99.52% Unkown
HY-W674241A 4-Ethylphenyl sulfate sodium Inducer / Unkown
HY-12242A GBR 12935 Inhibitor / Unkown
HY-138289 4-acetoxy MPT 98.8% Unkown
HY-165014 2C-I-FLY hydrochloride 99.3% Unkown
HY-169858 Prostaglandin E2 Inhibitor 3 Inhibitor 99.2% Unkown
HY-70062R Pevonedistat (Standard) 99.51% Unkown
HY-N16039 TAN-1030A Activator / Unkown
HY-101029A MBM-55S / Unkown
HY-101030 MBM-17 / Unkown
HY-120667 DS-5272 / Unkown
HY-12459 Pyrindamycin B Inhibitor / Unkown
HY-132302A Hu7691 free base Inhibitor / Unkown
HY-139798 Iboxamycin Inhibitor / Unkown
HY-100782 DL-AP7 Antagonist / Unkown
HY-10084 CK0106023 Inhibitor / Unkown
HY-100922 N-Acetylglycyl-D-glutamic acid Agonist / Unkown
HY-10109A AS-605240 potassium Inhibitor / Unkown
HY-101384 Ro 10-5824 Agonist / Unkown
HY-101699 AMG-076 free base Antagonist / Unkown
HY-101780A Tinostamustine hydrochloride Inhibitor / Unkown
HY-103357 LY288513 Antagonist / Unkown
HY-103567 Desmethyl-YM-298198 hydrochloride Antagonist / Unkown
HY-105052 SC 34301 / Unkown
HY-105236 (Rac)-Enadoline Agonist / Unkown
HY-105969 Dichloromethotrexate / Unkown
HY-106752 CI-936 Agonist / Unkown
HY-108497A L-803087 TFA Agonist / Unkown
HY-108538 Ethacrynic acid D5 Inhibitor / Unkown
HY-110020 rel-O-2050 Antagonist / Unkown
HY-111315 XEN103 Inhibitor / Unkown
HY-113354S1 Anserine-d4 hydrochloride / Unkown
HY-113866 E-55888 Agonist / Unkown
HY-113889 ZK112993 Antagonist / Unkown
HY-114542 LY 201409 / Unkown
HY-114651 Phenazoviridin / Unkown
HY-116046 GR 196429 Agonist / Unkown
HY-116597 L-783483 Agonist / Unkown
HY-117555 4010B-30 Activator / Unkown
HY-117569 KF24345 free base Inhibitor / Unkown
HY-117603 CM-10-18 Inhibitor / Unkown
HY-117660S1 Lincomycin-13C,d3 Inhibitor / Unkown
HY-117836 FAK-IN-16 Inhibitor / Unkown
HY-118030 RQ-00311651 Antagonist / Unkown
HY-118032 Bozepinib / Unkown
HY-118426 (Rac)-Tipifarnib Inhibitor / Unkown
HY-118574 UBP141 Antagonist / Unkown
HY-118626 PD-254552 Inhibitor / Unkown
HY-119519 OB-2 Inhibitor / Unkown
HY-119899 BO-0742 / Unkown
HY-120171 DH-376 Inhibitor / Unkown
HY-120225 NJK14047 Inhibitor / Unkown
HY-120561 PC-046 / Unkown
HY-120769 Pimprinine Inhibitor ≥90.0% Unkown
HY-120804 PH-46A Inhibitor / Unkown
HY-121431 FR-901235 / Unkown
HY-12153 JNJ-1930942 Modulator / Unkown
HY-121565 SaRI 59-801 Activator / Unkown
HY-122179 NUCC-555 Antagonist / Unkown
HY-122309 A-71497 / Unkown
HY-122518 8-Deazafolic acid Inhibitor / Unkown
HY-122655 HMCEF Inhibitor / Unkown
HY-122916 7-Acetyllycopsamine / Unkown
HY-123020 CYD-2-88 Antagonist 98.52% Unkown
HY-123237 KRC-108 / Unkown
HY-123357 IMM-H004 Inhibitor / Unkown
HY-124412S Paynantheine-d3 / Unkown
HY-124557 Mahanimbine Inhibitor / Unkown
HY-126185 Nibroxane Inhibitor / Unkown
HY-126835 A924 / Unkown
HY-126910 Mesyl Salvinorin B Agonist / Unkown
HY-127039 Antipain Inhibitor / Unkown
HY-129335 Chlorozotocin Inhibitor / Unkown
HY-129406 AF 698 / Unkown
HY-129577 Aplysin Inhibitor / Unkown
HY-131508 M&B 5124 Inhibitor / Unkown
HY-131954 5-HT3 antagonist 4 Antagonist / Unkown
HY-133533 O-2050 Antagonist / Unkown
HY-134191 Cryptochrome modulator 1 Modulator / Unkown
HY-143312C (S)-V-0219 Modulator / Unkown
HY-144668 RdRP-IN-4 Inhibitor / Unkown
HY-146001 Influenza virus-IN-4 Inhibitor / Unkown
HY-146151 γ-Secretase modulator 12 / Unkown
HY-146280 mGAT3/4-IN-1 Inhibitor / Unkown
HY-146293 HDAC6/HSP90-IN-1 Inhibitor / Unkown
HY-146297 Xanthine oxidoreductase-IN-2 Inhibitor / Unkown
HY-146401 CXCR4 antagonist 6 Antagonist / Unkown
HY-146435 Anti-inflammatory agent 22 Inhibitor / Unkown
HY-146458 Antibacterial agent 102 Inhibitor / Unkown
HY-146495 Antitubercular agent-19 Inhibitor / Unkown
HY-146496 Antitubercular agent-20 Inhibitor / Unkown
HY-146505 Tubulin polymerization-IN-6 / Unkown
HY-147335 6,9,12,15-Hexadecatetraenoic acid-ethyl ester / Unkown
HY-147529 mGluR2 modulator 3 Modulator / Unkown
HY-147678 GPR40 agonist 5 Agonist / Unkown
HY-147692 COX-2-IN-14 Inhibitor / Unkown
HY-148038 5-HT3 antagonist 5 Antagonist 99.75% Unkown
HY-148617 ALDH2 modulator 1 Modulator / Unkown
HY-149227 IDO1-IN-21 Inhibitor / Unkown
HY-149240 Anticancer agent 108 Inhibitor / Unkown
HY-149298 PSMA-IN-2 Inhibitor / Unkown
HY-149333 BO-1 Inhibitor / Unkown
HY-149521 PI3K-IN-47 Inhibitor / Unkown
HY-149776 RGH-560 / Unkown
HY-149940 SIMR3030 Inhibitor / Unkown
HY-149975 AMPA receptor modulator-4 Activator / Unkown
HY-150036 Anthramycin Antagonist / Unkown
HY-15041 NVP-SAA164 Antagonist / Unkown
HY-151153 HDAC1-IN-5 / Unkown
HY-155229 CBP/p300-IN-21 Inhibitor / Unkown
HY-155236 Ancistrotecine B Inhibitor / Unkown
HY-155328 GK444 Inhibitor / Unkown
HY-155329 GK718 Inhibitor / Unkown
HY-155529 FD1024 Inhibitor / Unkown
HY-155548 RORγt inverse agonist 31 Inhibitor / Unkown
HY-155652 ABCG2-IN-1 Inhibitor / Unkown
HY-155682 Antibacterial agent 150 Inhibitor / Unkown
HY-156792 RIOK2-IN-1 Inhibitor / Unkown
HY-157085 BX-2819 Inhibitor / Unkown
HY-157211 Anti-inflammatory agent 66 Inhibitor / Unkown
HY-157326 hMAO-B-IN-6 Inhibitor / Unkown
HY-157429 25N-N1-Nap Agonist / Unkown
HY-157430 BET-IN-21 Inhibitor / Unkown
HY-158006 SDX-7539 Inhibitor / Unkown
HY-158272 Penicillin/OVA Inhibitor / Unkown
HY-158434 IRAK1-IN-1 Inhibitor / Unkown
HY-158649 Fasnall benzenesulfonate / Unkown
HY-159602 BET BD2-IN-3 Inhibitor / Unkown
HY-159891 Microtubule destabilizing agent-2 / Unkown
HY-159895 PAR4 antagonist 7 Antagonist / Unkown
HY-159941 tau-0N4R-IN-1 Inhibitor / Unkown
HY-159942 5-HT7R antagonist 3 / Unkown
HY-160025 IDO antagonist-1 Antagonist / Unkown
HY-161281 α-Glucosidase-IN-49 Inhibitor / Unkown
HY-161372 PARP1/c-Met-IN-1 / Unkown
HY-161373 PI3Kα-IN-22 Inhibitor / Unkown
HY-161458 GSK-3β inhibitor 16 / Unkown
HY-161860 Antibacterial agent 233 Inhibitor / Unkown
HY-161863 Tubulin polymerization-IN-67 / Unkown
HY-161887 SMARCA2-IN-8 Inhibitor / Unkown
HY-161890 Antimycobacterial agent-8 Inhibitor / Unkown
HY-161893 Anti-MRSA agent 15 Inhibitor / Unkown
HY-162406 UNC8969 / Unkown
HY-162655A SLF80821178 hydrochloride Inhibitor / Unkown
HY-162703 Lipid-lowering agent-2 Activator / Unkown
HY-162727 GCS-12 / Unkown
HY-162751 Anticancer agent 249 / Unkown
HY-162760 COMT-IN-1 Inhibitor / Unkown
HY-162867 Photosensitizer-5 Inducer / Unkown
HY-162879 FAK inhibitor 7 / Unkown
HY-162893 SX29 Inhibitor / Unkown
HY-163003 Antitrypanosomal agent 19 Inhibitor / Unkown
HY-163066 α-Glucosidase-IN-44 Inhibitor / Unkown
HY-163300 NLRP3-IN-30 Inhibitor / Unkown
HY-163320 AChE/Aβ-IN-5 Inhibitor / Unkown
HY-163363 β-AR antagonist 2 Antagonist / Unkown
HY-163482 ELQ-596 Inhibitor / Unkown
HY-163484 ELQ-650 Inhibitor / Unkown
HY-163651 (R)-Vorbipiprant Antagonist / Unkown
HY-163797 WRN inhibitor 10 Inhibitor / Unkown
HY-163799 PRMT5-MTA-IN-1 Inhibitor / Unkown
HY-163816 Antiproliferative agent-53-d3 Inhibitor / Unkown
HY-163817 PARP1/2-IN-3 Inhibitor / Unkown
HY-163906 Anti-MRSA agent 16 Inhibitor / Unkown
HY-163978 YGZ-331 Activator / Unkown
HY-165425 KR31173 Antagonist / Unkown
HY-168021 MAO-A/SERT-IN-1 Inhibitor / Unkown
HY-168031 AChE/BChE-IN-21 / Unkown
HY-168444 CDK4/6-IN-23 Inhibitor / Unkown
HY-168742 V1a/V2 antagonist 1 Antagonist / Unkown
HY-169007 STAT3-IN-34 Inhibitor / Unkown
HY-169019 XJTU-L453 / Unkown
HY-169037 Δ8-Tetrahydrocannabinoquinone Inducer / Unkown
HY-169104 InhA-IN-8 Inhibitor / Unkown
HY-169394 5-HT1AR agonist 2 / Unkown
HY-169928 WRN inhibitor 14 Inhibitor / Unkown
HY-170659 NF-κB-IN-18 Inhibitor / Unkown
HY-170934 BW710 Inhibitor / Unkown
HY-170977 JAK1/STAT3-IN-1 Inhibitor / Unkown
HY-171035 PRL-295 Inhibitor / Unkown
HY-171732 FANFT / Unkown
HY-172456 JSF-4898 Inhibitor / Unkown
HY-172674 HPK1-IN-59 Inhibitor / Unkown
HY-172732 PRMT5-IN-50 Inhibitor / Unkown
HY-172781 HDAC6-IN-55 Inhibitor / Unkown
HY-173316 STING-IN-12 Inhibitor / Unkown
HY-173347 BLINK11 Inhibitor / Unkown
HY-173348 BLINK15 Inhibitor / Unkown
HY-173471 TRPA1 agonist-1 Agonist / Unkown
HY-173479 GLP-1R agonist 30 Agonist / Unkown
HY-173518 SIN 14 / Unkown
HY-175042 D-myo-Inositol-1,3,4,5,6-pentaphosphate ammonium salt Inhibitor 98% Unkown
HY-176052 PPO-allene Inhibitor / Unkown
HY-176063 TRPV1 antagonist 11 / Unkown
HY-176288 eIF4E/eIF4G PPI-IN-1 / Unkown
HY-176775 TPP-IOA Inhibitor / Unkown
HY-179379 EP4 receptor agonist 3 prodrug / Unkown
HY-179463 BKI 1708 Inhibitor / Unkown
HY-180291 Anti-inflammatory agent 109 Inhibitor / Unkown
HY-180785 G243-1720 Inhibitor / Unkown
HY-180829 HDAC6-IN-71 Inhibitor / Unkown
HY-182418 UR-11353 / Unkown
HY-183340 Antibacterial agent 341 / Unkown
HY-40156A Mycobacterium Tuberculosis-IN-5 Inhibitor / Unkown
HY-B0693S Ranitidine-d6 / Unkown
HY-B1002S Oxolinic acid-d5 Inhibitor 98.0% Unkown
HY-B2046S Simazine-d10 / Unkown
HY-B2185 Tipepidine citrate / Unkown
HY-D1066 NIR-Thiol dinitrobenzenesulfonate / Unkown
HY-D1535 IR 813 perchlorate / Unkown
HY-D2095 Medical fluorophore 33 / Unkown
HY-D2988 BIN-3 / Unkown
HY-N0219R Bicuculline (Standard) Antagonist / Unkown
HY-N10312 Yadanzigan Inhibitor / Unkown
HY-N10341 Centaureidin Activator / Unkown
HY-N11021 Feruloyl tyramine / Unkown
HY-N11723 Catenarin Inhibitor / Unkown
HY-N11730 6',7'-Epoxyrotenone / Unkown
HY-N12042 Taxamairin B Inhibitor / Unkown
HY-N12249 7-Deoxy-trans-dihydronarciclasine Inhibitor / Unkown
HY-N14193 Estatin B Inhibitor / Unkown
HY-N15177 Δ9-THCB Agonist / Unkown
HY-N15703 Norisocorydine / Unkown
HY-N18124 1-O-Tigloyl-1-O-debenzoylohchinal / Unkown
HY-N5126 Juncusol / Unkown
HY-N7047 8-Epidiosbulbin E acetate Inhibitor 98.42% Unkown
HY-N7271R Solanidine (Standard) / Unkown
HY-N7944 Eucommiol / Unkown
HY-N9475 Betulonaldehyde Inhibitor / Unkown
HY-P10029 Sakura-6 Inhibitor / Unkown
HY-P10057 cpm-1285 Inducer / Unkown
HY-P10110 retro-inverso TAT-Beclin 1 (D-amino acid) Inducer / Unkown
HY-P10721 Plectasin Inhibitor / Unkown
HY-P11405 [D-Arg1,D-Trp5,7,9,Leu11]-Substance P Antagonist / Unkown
HY-P11431 Cyclo(Gly-Pro) / Unkown
HY-P11467 Gy-CATH / Unkown
HY-P1259 PR-39 Inhibitor / Unkown
HY-P1302A Orphanin FQ(1-11) TFA Agonist / Unkown
HY-P1949 Cyclic MKEY / Unkown
HY-P3102A GLP-1(32-36)amide TFA / Unkown
HY-P3707 Tumor targeted pro-apoptotic peptide Inducer / Unkown
HY-P5130 Big endothelin-1 (rat 1-39) Ligand / Unkown
HY-P5890 YVAD-CHO Inhibitor / Unkown
HY-RS08425 MICAL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W004681 5-Hydroxy-2-methylpyridine 99.97% Unkown
HY-W040276 Diafen NN / Unkown
HY-W097106 (S)-3-N-Cbz-Amino-succinimide 97.0% Unkown
HY-W1142093 ActRIIB-IN-4 / Unkown
HY-W331017 1-Hexacosanoyl-sn-glycero-3-phosphocholine / Unkown
HY-W744266 9α,10α-Epoxyhexahydrocannabinol / Unkown
HY-W795264 FR900098 Inhibitor / Unkown
HY-100442S Paquinimod-d5 Inhibitor / Unkown
HY-100840 (S)-4C3HPG / Unkown
HY-101775 9-Hydroxyellipticin Inhibitor / Unkown
HY-103163 (±)-5'-Chloro-5'-deoxy-ENBA Agonist / Unkown
HY-103388 NCX 466 Inhibitor / Unkown
HY-103567A Desmethyl-YM-298198 Antagonist / Unkown
HY-109044S Tapinarof-d5 Agonist / Unkown
HY-116799 NSC 145669 Inhibitor / Unkown
HY-117446 AS-1669058 Agonist / Unkown
HY-118537 ICI 56780 Inhibitor / Unkown
HY-118802 4-Hydroxy DPT / Unkown
HY-118803 AS1468240 Inhibitor / Unkown
HY-119218 LH 1 / Unkown
HY-119955 Amflutizole Inhibitor / Unkown
HY-120450 CL-55 Inhibitor / Unkown
HY-120462 Genz-669178 Inhibitor / Unkown
HY-12242B GBR 12935 fumarate Inhibitor / Unkown
HY-124499 RUC-1 Inhibitor / Unkown
HY-12580 RO5353 MDM2 Inhibitor / Unkown
HY-12610 Carbonic anhydrase inhibitor 27 Inhibitor / Unkown
HY-126170 Valanimycin Inhibitor / Unkown
HY-127014 Julimycin B2 Inhibitor / Unkown
HY-129318 MBX-1066 Inhibitor / Unkown
HY-129347 Lankacyclinol A Inhibitor / Unkown
HY-134314 8-Nitro-cGMP Inducer / Unkown
HY-134579 Chaetomellic acid A Inhibitor / Unkown
HY-138100 Hyalodendrin Inhibitor / Unkown
HY-138291 Ethoxyquin dimer 98.70% Unkown
HY-139240 Cannabidihexol / Unkown
HY-147548 Keap1-Nrf2-IN-10 Inhibitor / Unkown
HY-161728 Antibacterial agent 223 Inhibitor / Unkown
HY-161935 6-(12-Tridecene-1-yl)-2,4-Dihydroxy benzoic acid Inhibitor / Unkown
HY-161937 Antibacterial agent 236 Inhibitor / Unkown
HY-164384 DFX117 / Unkown
HY-164462 BHA536 / Unkown
HY-164547 WHN-88 Inhibitor / Unkown
HY-168355 Δ8-THC methyl ether Ligand / Unkown
HY-168365 (±)-Pellotine hydrochloride / Unkown
HY-168368 exo-Tetrahydrocannabivarin Ligand / Unkown
HY-168629 FXR agonist 9 Inhibitor / Unkown
HY-168792 (±)-9-Nor-9α-hydroxy Hexahydrocannabinol / Unkown
HY-170717 3-Methylnordiazepam / Unkown
HY-172335 C9-200 / Unkown
HY-180129 SARS-CoV-2-IN-120 Inhibitor / Unkown
HY-180360 Antiparasitic agent-34 Inhibitor / Unkown
HY-180936 FBPase-IN-6 / Unkown
HY-21193R Perfluoropentanoic acid (Standard) / Unkown
HY-B0448S2 Phenytoin-d5 Inhibitor / Unkown
HY-N12171 Isoreserpiline Inhibitor / Unkown
HY-N12719 Isocampneoside I / Unkown
HY-N13715 Thalicminine / Unkown
HY-N13894 Auramycin A Inhibitor / Unkown
HY-N13895 Auramycin B Inhibitor / Unkown
HY-N14018 Glidobactin A Inhibitor / Unkown
HY-N14200 Maridomycin II Inhibitor / Unkown
HY-N14201 Maridomycin IV Inhibitor / Unkown
HY-N14202 Maridomycin V Inhibitor / Unkown
HY-N14203 Maridomycin VI Inhibitor / Unkown
HY-N14586 Roridin J / Unkown
HY-N14941 Phleomycin G Inhibitor / Unkown
HY-N1503R Methyl deacetylasperulosidate (Standard) / Unkown
HY-N15180 Corynantheidine / Unkown
HY-N4031 Humantenine Chemical 98% Unkown
HY-N4243 Neocurdione / Unkown
HY-P0009S1 Cetrorelix-d10 Antagonist / Unkown
HY-P10200 CP7-FP13-2 Inhibitor / Unkown
HY-P4885 Glp-amyloid-β (3-40) peptide (human) / Unkown
HY-W188178 N-Mitrososarcosine / Unkown
HY-W369099 HJC0152 free base 98.30% Unkown
HY-W658325 P-Decyloxyaniline / Unkown
HY-W665796 N-Methyl-N-nitroso-2-propanamine / Unkown
HY-W681659 Flutoprazepam Inhibitor / Unkown
HY-109506S10 DPPC-13C3 / Unkown
Inhibitory Antibodies (8)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P99123 Anti-Mouse CD28 Antibody (37.51) 95.00% Unkown
HY-P99148 Anti-Mouse/Rat/Rabbit TNF alpha Antibody (TN3-19.12) Inhibitor 99.24% Unkown
HY-P99129 Anti-Mouse CD8a Antibody (53-6.7) Inhibitor 98.18% Unkown
HY-P990282 Anti-Mouse CD24 Antibody (M1/69) Inhibitor ≥95.0% Unkown
HY-P99620 Firivumab Inhibitor 95.00% Unkown
HY-P990812 Anti-Mouse myeloperoxidase/MPO Antibody (6D1) Inhibitor 99.71% Unkown
HY-P991433 BIIB036 Activator / Unkown
HY-P992059 Anti-Mouse CD1d Antibody (1B1) Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus MICAL1 VGNC VGNC:63493
Bos taurus MICAL1 VGNC VGNC:31457
Mus musculus MICAL1 MGD MGI:2385847
Rattus norvegicus MICAL1 RGD RGD:1309386
Canis familiaris MICAL1 VGNC VGNC:49758
Macaca mulatta MICAL1 VGNC VGNC:74547
Others MICAL1 NCBI