2. Gene
  3. KRAS - KRAS proto-oncogene, GTPase Gene

KRAS - KRAS proto-oncogene, GTPase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)

Also known as K-RAS

Gene ID: 403871 | Gene type: protein coding

About KRAS

Primary_assembly 27: 22,456,012-22,495,428 forward strand.ROS_Cfam_1.0:CM025126.1

This gene has 2 transcripts (splice variants), 201 orthologues and 35 paralogues.

KRAS Products(3)

mRNA Protein Name
XM_038438708.1 XP_038294636.1 GTPase KRas isoform X1
XM_038438710.1 XP_038294638.1 GTPase KRas isoform X3
XM_038438709.1 XP_038294637.1 GTPase KRas isoform X2

KRAS Protein Structure

H_N_K_Ras_like

H_N_K_Ras_like: cd04138 (2 - 163)

  • 0
  • 100
  • 200
  • 227 a.a.
Protein Preferred Names Protein Names

GTPase KRas

ras p21

v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Related Agents

Approval
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-114277 Sotorasib Inhibitor 99.70% Yes
HY-130149 Adagrasib Inhibitor 99.96% Unkown
HY-15136 Lonafarnib 99.85% Yes
HY-B0984 Fendiline hydrochloride 99.78% Unkown
HY-114277A Sotorasib racemate 98.99% Unkown
HY-B0984A Fendiline 99.41% Unkown
HY-114277R Sotorasib (Standard) Inhibitor 99.25% Unkown
HY-B0984R Fendiline hydrochloride (Standard) 99.76% Unkown
Clinical Phase
Bioactive Molecules (21)
Cat. No. Product Name Effect
Purity Phase
HY-176785S MCB-294 / Phase 4
HY-148439 Daraxonrasib Inhibitor 99.96% Phase 3
HY-145928 Divarasib Inhibitor 99.31% Phase 3
HY-132844 Tunlametinib Inhibitor 99.53% Phase 3
HY-139612 Opnurasib Inhibitor 98.20% Phase 3
HY-145928B Divarasib adipate Inhibitor 99.20% Phase 3
HY-156819 Zoldonrasib 99.73% Phase 2
HY-160699 DCC-3116 Inhibitor 99.84% Phase 2
HY-159127 HRS-4642 98.38% Phase 2
HY-143589 Glecirasib Inhibitor 99.20% Phase 2
HY-114491 Rineterkib Inhibitor 98.79% Phase 2
HY-114491A Rineterkib hydrochloride Inhibitor 99.81% Phase 2
HY-134813 MRTX1133 Inhibitor 99.97% Phase 1
HY-173629 RMC-5127 99.96% Phase 1
HY-158107 BBO-8520 Inhibitor 99.90% Phase 1
HY-159852 BBO-10203 99.12% Phase 1
HY-147245 Basroparib Inhibitor 98.91% Phase 1
HY-15610 GDC-0623 98.74% Phase 1
HY-152848 Fulzerasib Inhibitor 99.60% Phase 1
HY-16111 BMS-214662 Inhibitor 99.86% Phase 1
HY-16373 CP-609754 Inhibitor 99.49% Phase 1
Pre-clinical Phase
Bioactive Molecules (532)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-156498 RMC-7977 Inhibitor 99.48% Unkown
HY-153724 BI-2865 99.65% Unkown
HY-16909 Leptomycin B Inhibitor 99.79% Unkown
HY-147214 GNE-7883 Inhibitor 99.54% Unkown
HY-153346 Elironrasib 99.65% Unkown
HY-158115 NST-628 Inhibitor 98.61% Unkown
HY-125817 BI-3406 Inhibitor 99.95% Unkown
HY-173632 AMG410 Inhibitor 99.75% Unkown
HY-126247 BI-2852 Inhibitor 99.46% Unkown
HY-112929 DT-061 Activator 99.95% Unkown
HY-157228 ACBI3 Degrader 99.47% Unkown
HY-148273 Setidegrasib Inhibitor 99.65% Unkown
HY-156002 LUNA18 Inhibitor 99.76% Unkown
HY-135985 DCLK1-IN-1 99.35% Unkown
HY-153723 BI-2493 Inhibitor 99.79% Unkown
HY-15872A FTI-277 hydrochloride 98.29% Unkown
HY-132980 Olomorasib Inhibitor 99.88% Unkown
HY-114398 BAY-293 Inhibitor 98.97% Unkown
HY-138188 KRA-533 Agonist 98.73% Unkown
HY-137516 LC-2 Inhibitor 98.48% Unkown
HY-159788 PROTAC K-Ras Degrader-4 Degrader 99.01% Unkown
HY-19713 LJI308 Inhibitor 99.07% Unkown
HY-W095670 2,4,7-Trichloro-8-fluoropyrido[4,3-d]pyrimidine 99.95% Unkown
HY-161176 PROTAC KRAS G12D degrader 1 98.32% Unkown
HY-128350 FGTI-2734 Inhibitor 99.85% Unkown
HY-128574 D927 Activator 99.46% Unkown
HY-U00418 ARS-1620 Inhibitor 99.59% Unkown
HY-136265 BC-LI-0186 Inhibitor 99.20% Unkown
HY-122862 RAS inhibitor Abd-7 Inhibitor 99.57% Unkown
HY-148409 MMRi62 99.59% Unkown
HY-173637 AZD0022 Inhibitor 98.36% Unkown
HY-148098 Pan KRas-IN-1 Inhibitor 99.31% Unkown
HY-162809 XMU-MP-9 99.12% Unkown
HY-18303 AMG-47a Inhibitor 99.19% Unkown
HY-159190 HRX-0233 Inhibitor 98.92% Unkown
HY-129523 PROTAC K-Ras Degrader-1 Inhibitor 99.90% Unkown
HY-160023 Elisrasib 98.50% Unkown
HY-N0735 Phellodendrine chloride 99.68% Unkown
HY-156671 RMC-4998 99.31% Unkown
HY-114436 MRTX-1257 Inhibitor 99.71% Unkown
HY-18707 K-Ras(G12C) inhibitor 12 99.57% Unkown
HY-176786 MCB-36 98.43% Unkown
HY-13495 ML281 98.04% Unkown
HY-15747 Deltarasin Inhibitor 99.12% Unkown
HY-176134 RP03707 Degrader 98.00% Unkown
HY-49385 E3 ligase Ligand 64 ≥98.0% Unkown
HY-W095672A (2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizine-7a(5H)-methanol 99.82% Unkown
HY-162431 Calderasib Inhibitor 99.82% Unkown
HY-173405 VVD-699 Inhibitor 99.83% Unkown
HY-122914 KRAS inhibitor-3 Inhibitor 99.87% Unkown
HY-128522 ARS-1323-alkyne Inhibitor 99.59% Unkown
HY-135700 Mevalonolactone 98.0% Unkown
HY-137497 KRAS inhibitor-9 99.85% Unkown
HY-176523 KRAS G12D-IN-29 Inhibitor 99.93% Unkown
HY-139186 PROTAC KRAS G12C degrader-1 Degrader 99.15% Unkown
HY-W016889 CFL-137 Inhibitor 99.92% Unkown
HY-154959 AZD4747 Inhibitor 99.07% Unkown
HY-15879 LB42708 ≥99.0% Unkown
HY-161233A BTX-6654 formate 98.85% Unkown
HY-161906 SD-066-4 Inhibitor 99.96% Unkown
HY-168054 PROTAC K-Ras Degrader-3 Degrader 99.75% Unkown
HY-76986 5-Iodoindolin-2-one 99.25% Unkown
HY-19706 ARS-853 98.39% Unkown
HY-138295 KRAS inhibitor-10 Inhibitor 99.92% Unkown
HY-151523 KRas G12R inhibitor 1 Inhibitor 98.40% Unkown
HY-134654 MRTX849 analog 24 98.01% Unkown
HY-41832 4,6-Dichloro-2-(methylthio)pyrimidine 99.32% Unkown
HY-U00416 ARS-1323 Inhibitor 99.67% Unkown
HY-128350A FGTI-2734 mesylate Inhibitor 99.65% Unkown
HY-18674 K-Ras-IN-1 Inhibitor 98.00% Unkown
HY-114277B Sotorasib isomer Control 98.85% Unkown
HY-114277S Sotorasib-d7 Inhibitor 98.90% Unkown
HY-146243 TH-Z835 99.58% Unkown
HY-156529 pan-KRAS-IN-2 Inhibitor 98.01% Unkown
HY-159652 KRAS inhibitor-31 Inhibitor 99.36% Unkown
HY-162960 pan-KRAS-IN-18 Degrader 99.93% Unkown
HY-P2265A SAH-SOS1A TFA Inhibitor 96.55% Unkown
HY-W1126235 DS02312223 Activator 98.24% Unkown
HY-141477 RM-018 Inhibitor 95.50% Unkown
HY-15873A FTI 276 TFA Inhibitor 98.06% Unkown
HY-128590 PHT-7.3 Inhibitor 99.29% Unkown
HY-147008 XP-524 Inhibitor 98.02% Unkown
HY-125847 Salvianolic acid F 99.50% Unkown
HY-126247B (R)-BI-2852 Control 97.32% Unkown
HY-139047 SW157765 Inhibitor 98.08% Unkown
HY-177106 ADT-1004 Inhibitor 98.16% Unkown
HY-181420A BBO-11818 / Unkown
HY-16662 Oncrasin-1 98.16% Unkown
HY-175870 Eras-4001 Inhibitor 98.27% Unkown
HY-151517 SOS1-IN-14 Inhibitor 99.60% Unkown
HY-16967 MM41 98.89% Unkown
HY-104067 Naphthol AS-MX phosphate Inhibitor 99.50% Unkown
HY-136726 CGP-82996 Inhibitor 98.12% Unkown
HY-153663 TH-Z827 Inhibitor 95.12% Unkown
HY-156500 ICMT-IN-1 Inhibitor 98.43% Unkown
HY-161177 PROTAC SARS-CoV-2 3CLPro degrader 2 Degrader 98.59% Unkown
HY-161235 BTX-7312 98.35% Unkown
HY-164315 KRAS G12C inhibitor 67 Inhibitor 98.80% Unkown
HY-176954 RSC-1255 99.91% Unkown
HY-P10436 Braftide Inhibitor 99.51% Unkown
HY-P3277 KRpep-2d Inhibitor 96.51% Unkown
HY-130991 K-Ras ligand-Linker Conjugate 6 / Unkown
HY-163939 RGT-018 Inhibitor 99.77% Unkown
HY-170428 IPS-06061 Degrader / Unkown
HY-132966 ASP2453 Inhibitor 98.28% Unkown
HY-144661 KRAS G12D inhibitor 14 98.88% Unkown
HY-115880A KRAS G12D inhibitor 3 TFA Inhibitor 98.18% Unkown
HY-134977 Atrovastatin-PEG3-FITC Inhibitor 99.23% Unkown
HY-145737A PROTAC SOS1 degrader-1 TFA Agonist 98.38% Unkown
HY-159474 KRAS inhibitor-24 Inhibitor 95.03% Unkown
HY-159474A (1R)-KRAS inhibitor-24 Inhibitor 98.29% Unkown
HY-159591 YK-8S Inhibitor / Unkown
HY-163299 pan-KRAS-IN-5 96.70% Unkown
HY-163594 KRAS-IN-59 Inhibitor 99.66% Unkown
HY-163595 KRAS G12D-IN-31 Inhibitor 98.53% Unkown
HY-176792 ACBI-4 Degrader 98.01% Unkown
HY-177511 KRAS G12D-IN-30 Inhibitor 99.38% Unkown
HY-W998345 SMART1 Inhibitor 99.87% Unkown
HY-157029S KRASG12D-IN-1 Inhibitor 98.07% Unkown
HY-115489A GGTI-286 TFA Inhibitor / Unkown
HY-128771 K-Ras G12C-IN-4 Inhibitor 99.19% Unkown
HY-142160 GNE-9815 Inhibitor 98.94% Unkown
HY-145962A MRTX-EX185 formic Inhibitor 97.13% Unkown
HY-151881 SOS1-IN-15 Inhibitor 98.04% Unkown
HY-107720 ARL 17477 Inhibitor 99.02% Unkown
HY-122641 Deltasonamide 1 Inhibitor 99.15% Unkown
HY-143599 KRAS G12D inhibitor 8 Inhibitor / Unkown
HY-145615 Pomalidomide-C12-NH2 hydrochloride 96.51% Unkown
HY-153821 PROTAC KRAS G12C degrader-2 Degrader 98.45% Unkown
HY-154313 Spiclomazine Inhibitor 99.56% Unkown
HY-156671A RMC-4998 formic 99.02% Unkown
HY-161066 KRAS G13D-IN-1 Inhibitor / Unkown
HY-162445 KRASG12D-IN-3 Inhibitor 98.38% Unkown
HY-168669 PROTAC K-Ras Degrader-5 97.84% Unkown
HY-172626A (R)-KRAS G12D inhibitor 28 hydrochloride dihydrate Inhibitor 99.58% Unkown
HY-173637A (S)-AZD0022 Inhibitor 95.16% Unkown
HY-N0427 Phellodendrine 99.60% Unkown
HY-P5192 KRAS G12D(8-16) 97.73% Unkown
HY-16111A BMS-214662 hydrochloride Inhibitor 98.54% Unkown
HY-RS07425 KRAS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-115489 GGTI-286 Inhibitor / Unkown
HY-134813A MRTX1133 formic Inhibitor 98.23% Unkown
HY-157031S KRASG12D-IN-2 Inhibitor 98.11% Unkown
HY-U00417 ARS-1630 Inhibitor 98.10% Unkown
HY-139894 KRAS G12D inhibitor 5 Inhibitor / Unkown
HY-145962 MRTX-EX185 Inhibitor / Unkown
HY-158008 (R)-G12Di-7 Inhibitor 98.42% Unkown
HY-161233 BTX-6654 / Unkown
HY-172237 Sosimerasib Inhibitor 98.63% Unkown
HY-18606 K-Ras G12C-IN-3 Inhibitor 99.94% Unkown
HY-186087 RM-046 / Unkown
HY-125872 KRAS G12C inhibitor 14 Inhibitor 99.00% Unkown
HY-125873 KRAS G12C inhibitor 15 Inhibitor 98.47% Unkown
HY-130707 K-Ras ligand-Linker Conjugate 3 / Unkown
HY-130823 K-Ras ligand-Linker Conjugate 5 99.79% Unkown
HY-142460 KRAS G12C inhibitor 28 Inhibitor 99.94% Unkown
HY-153262 (7R)-Elisrasib Inhibitor 99.52% Unkown
HY-112491 KRas G12C inhibitor 1 Inhibitor / Unkown
HY-112929B (1S,2S,3R)-DT-061 99.77% Unkown
HY-114398A (S)-BAY-293 97.8% Unkown
HY-117935 GGTI-286 hydrochloride Inhibitor / Unkown
HY-123929 PAWI-2 99.29% Unkown
HY-124761 Poloppin Inhibitor 99.40% Unkown
HY-130819 Tos-PEG4-THP 95.0% Unkown
HY-130820 THP-PEG4-Pyrrolidine(N-Boc)-CH2OH 95.0% Unkown
HY-130821 THP-PEG4-Pyrrolidine(N-Me)-CH2OH 95.0% Unkown
HY-134811 KRAS G12D inhibitor 1 Inhibitor / Unkown
HY-139402 MRTX849 acid Inhibitor 99.84% Unkown
HY-139612A (S)-Opnurasib Inhibitor 99.32% Unkown
HY-143603 KRAS G12D inhibitor 10 Inhibitor 88.89% Unkown
HY-144657A (4S)-PROTAC SOS1 degrader-1 diTFA Inhibitor 98.09% Unkown
HY-148278 BI-0474 Inhibitor 99.83% Unkown
HY-153413 Kras4B G12D-IN-1 Inhibitor 98.01% Unkown
HY-153662 TH-Z816 Inhibitor 98.92% Unkown
HY-154959A (9R,12aR)-AZD4747 Control 98.90% Unkown
HY-158107A (4R)-BBO-8520 Inhibitor / Unkown
HY-161767 JWJ-01-306 Inhibitor / Unkown
HY-162100 MR-2088 Inhibitor 99.50% Unkown
HY-164350 KRAS inhibitor-27 Inhibitor / Unkown
HY-164365 PROTAC K-Ras Degrader-2 Degrader / Unkown
HY-164493 KRASG12C IN-13 Inhibitor 99.01% Unkown
HY-164749 K-Ras-IN-4 Inhibitor / Unkown
HY-168012 Pan-RAS-IN-6 Inhibitor / Unkown
HY-168847 INCB159020 Inhibitor / Unkown
HY-171255 KRAS G12D inhibitor 26 Inhibitor 98.39% Unkown
HY-176489 PROTAC pan-KRAS degrader-1 / Unkown
HY-178194 SHY-855 Inhibitor / Unkown
HY-178211 SHY-867 Inhibitor / Unkown
HY-181555 IACS-56676 Inhibitor / Unkown
HY-186001 RMC-9945 / Unkown
HY-P11294 KLVVVGADGVGKSALTI 98.26% Unkown
HY-P11355A KRAS WT Peptide TFA 98.61% Unkown
HY-P11356A KRAS G12V Peptide TFA Activator 97.01% Unkown
HY-P11357A KRAS G12C Peptide TFA Activator 95.15% Unkown
HY-P3277A KRpep-2d TFA Inhibitor 98.11% Unkown
HY-RS07426 Kras Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W041315 CFL-120 Inhibitor 98.0% Unkown
HY-12446 K-Ras(G12C) inhibitor 9 Inhibitor 98.5% Unkown
HY-15747A Deltarasin hydrochloride Inhibitor 98.07% Unkown
HY-18605 K-Ras G12C-IN-2 Inhibitor 99.21% Unkown
HY-48187 KRAS inhibitor-39 98.36% Unkown
HY-W595110 3-((4-(Piperidin-4-yl)phenyl)amino)piperidine-2,6-dione (hydrochloride) 99.72% Unkown
HY-18604 K-Ras G12C-IN-1 Inhibitor 98.19% Unkown
HY-135864 KRAS inhibitor-6 Inhibitor / Unkown
HY-135865 KRAS inhibitor-7 Inhibitor / Unkown
HY-135866 KRAS inhibitor-8 Inhibitor / Unkown
HY-115880 KRAS G12D inhibitor 3 Inhibitor / Unkown
HY-129775 K-Ras ligand-Linker Conjugate 1 / Unkown
HY-129776 K-Ras ligand-Linker Conjugate 2 / Unkown
HY-132920 KRAS mutant protein inhibitor 1 Inhibitor / Unkown
HY-142458 KRAS G12C inhibitor 27 Inhibitor / Unkown
HY-142487 KRAS G12C inhibitor 32 Inhibitor / Unkown
HY-180200 RNK08954 Inhibitor / Unkown
HY-108887 Anticancer agent 124 Inhibitor / Unkown
HY-114168 KRAS G12C inhibitor 5 Inhibitor / Unkown
HY-115516 BI-1388 Inhibitor / Unkown
HY-125874 KRAS G12C inhibitor 16 Inhibitor / Unkown
HY-125875 KRAS G12C inhibitor 17 Inhibitor / Unkown
HY-126292 KRAS G12C inhibitor 13 Inhibitor / Unkown
HY-130260 KRAS inhibitor-4 Inhibitor / Unkown
HY-130822 K-Ras ligand-Linker Conjugate 4 98.76% Unkown
HY-132979 KRAS G12C inhibitor 18 Inhibitor / Unkown
HY-146544 KRAS inhibitor-14 Inhibitor / Unkown
HY-146546 KRAS inhibitor-16 Inhibitor / Unkown
HY-150927 G12Si-2 Inhibitor / Unkown
HY-151287 KRAS inhibitor-20 Inhibitor / Unkown
HY-162249 ASP6918 Inhibitor / Unkown
HY-183553 AUBE00 Inhibitor / Unkown
HY-107841 K-Ras(G12C) inhibitor 6 Inhibitor 99.08% Unkown
HY-108436 Deltazinone 1 Inhibitor 98.79% Unkown
HY-112492 KRas G12C inhibitor 2 Inhibitor / Unkown
HY-112493 KRas G12C inhibitor 3 Inhibitor / Unkown
HY-112494 KRas G12C inhibitor 4 Inhibitor / Unkown
HY-114436S MRTX-1257-d6 / Unkown
HY-115907 K20 Inhibitor / Unkown
HY-115907A (rac)-K20 / Unkown
HY-116428 L-744832 / Unkown
HY-117807 A-176120 Inhibitor / Unkown
HY-120763 LB42908 Inhibitor / Unkown
HY-122152 Spiclomazine hydrochloride Inhibitor / Unkown
HY-122641D Deltasonamide 1 TFA Inhibitor 99.70% Unkown
HY-125199 ULK-100 Inhibitor / Unkown
HY-125335 Oligomycin D / Unkown
HY-126180 BAY-866 Inhibitor / Unkown
HY-128414 KRAS G12C-IN-72 Inhibitor / Unkown
HY-128762 ML256 Inhibitor / Unkown
HY-130991A K-Ras ligand-Linker Conjugate 6 formate 98.93% Unkown
HY-134505 Avicin G Inhibitor / Unkown
HY-13497 STK33-IN-1 Inhibitor / Unkown
HY-137516A LC-2 epimer / Unkown
HY-137971 (±)-Spiro-oxanthromicin A Inhibitor / Unkown
HY-139403 MRTX849 ethoxypropanoic acid Antagonist / Unkown
HY-139612B (Rac)-Opnurasib Inhibitor / Unkown
HY-139910 KRAS G12D inhibitor 6 Inhibitor / Unkown
HY-139911 KRAS G12D inhibitor 7 Inhibitor / Unkown
HY-142457 KRAS G12C inhibitor 26 Inhibitor / Unkown
HY-142478 KRAS G12C inhibitor 29 Inhibitor / Unkown
HY-142481 KRAS G12C inhibitor 30 Inhibitor / Unkown
HY-142485 KRAS G12C inhibitor 31 Inhibitor / Unkown
HY-142490 KRAS G12C inhibitor 33 Inhibitor / Unkown
HY-142511 KRAS G12C inhibitor 34 Inhibitor / Unkown
HY-142945 KRAS G12C inhibitor 43 Inhibitor / Unkown
HY-142946 KRAS G12C inhibitor 44 Inhibitor / Unkown
HY-142947 KRAS G12C inhibitor 45 Inhibitor / Unkown
HY-142948 KRAS G12C inhibitor 46 Inhibitor / Unkown
HY-143359 COTI-219 Inhibitor / Unkown
HY-143588 KRAS G12C inhibitor 35 Inhibitor / Unkown
HY-143590 KRAS G12C inhibitor 37 Inhibitor / Unkown
HY-143591 KRAS G12C inhibitor 38 Inhibitor / Unkown
HY-143592 KRAS G12C inhibitor 39 Inhibitor / Unkown
HY-143594 KRAS G12C inhibitor 40 Inhibitor / Unkown
HY-143596 KRAS G12C inhibitor 41 Inhibitor / Unkown
HY-143598 KRAS G12C inhibitor 42 Inhibitor / Unkown
HY-143602 KRAS G12D inhibitor 9 Inhibitor / Unkown
HY-143604 KRAS G12D inhibitor 11 Inhibitor / Unkown
HY-143606 KRAS G12D inhibitor 12 Inhibitor / Unkown
HY-143607 KRAS G12D inhibitor 13 Inhibitor / Unkown
HY-144207 SOS1-IN-9 Inhibitor / Unkown
HY-144210 SOS1-IN-6 Inhibitor / Unkown
HY-144211 SOS1-IN-7 Inhibitor / Unkown
HY-144213 SOS1-IN-10 Inhibitor / Unkown
HY-144323 YF135 Inhibitor / Unkown
HY-144657 (4S)-PROTAC SOS1 degrader-1 Inhibitor / Unkown
HY-145017 KRAS G12C inhibitor 20 Inhibitor / Unkown
HY-145018 KRAS G12C inhibitor 21 Inhibitor / Unkown
HY-145019 KRAS G12C inhibitor 22 Inhibitor / Unkown
HY-145020 KRAS G12C inhibitor 23 Inhibitor / Unkown
HY-145022 KRAS G12C inhibitor 25 Inhibitor / Unkown
HY-145047 SOS1-IN-4 Inhibitor / Unkown
HY-145048 SOS1-IN-5 Inhibitor / Unkown
HY-145436 KRAS inhibitor-11 Inhibitor / Unkown
HY-145737 PROTAC SOS1 degrader-1 Agonist / Unkown
HY-146061 KRAS G12C inhibitor 48 Inhibitor / Unkown
HY-146475 KRAS inhibitor-17 Inhibitor / Unkown
HY-146476 KRAS inhibitor-18 Inhibitor / Unkown
HY-146533 KRAS inhibitor-12 Inhibitor / Unkown
HY-146537 KRAS G12C inhibitor 47 Inhibitor / Unkown
HY-146543 KRAS inhibitor-13 Inhibitor / Unkown
HY-146545 KRAS inhibitor-15 Inhibitor / Unkown
HY-147595 KRAS G12D inhibitor 15 Inhibitor / Unkown
HY-147631 KRAS G12C inhibitor 50 Inhibitor / Unkown
HY-147632 KRAS G12C inhibitor 51 Inhibitor / Unkown
HY-147633 KRAS G12C inhibitor 52 Inhibitor / Unkown
HY-147634 KRAS G12C inhibitor 53 Inhibitor / Unkown
HY-147635 KRAS G12C inhibitor 54 Inhibitor / Unkown
HY-147636 KRAS G12C inhibitor 55 Inhibitor / Unkown
HY-148260 KRAS G12D inhibitor 16 Inhibitor / Unkown
HY-148261 KRAS G12C inhibitor 56 Inhibitor / Unkown
HY-149607 SHP2-IN-22 Inhibitor / Unkown
HY-149705 ICMT-IN-7 Inhibitor / Unkown
HY-149709 ICMT-IN-35 Inhibitor / Unkown
HY-151288 KRAS inhibitor-21 Inhibitor / Unkown
HY-15136B (Rac)-Lonafarnib / Unkown
HY-151571 ZG1077 Inhibitor / Unkown
HY-151968 KRAS G12C inhibitor 57 Inhibitor / Unkown
HY-151999 KRAS G12C inhibitor 65 Inhibitor / Unkown
HY-152145 PROTAC SOS1 degrader-3 / Unkown
HY-152248 ARS-2102 Inhibitor / Unkown
HY-153412 KRAS inhibitor-22 Degrader / Unkown
HY-153461 KRAS G12C inhibitor 58 Inhibitor / Unkown
HY-153555 KRAS G12D modulator-1 Modulator / Unkown
HY-153858 PHI-501 Inhibitor / Unkown
HY-153880 KRAS degrader-1 Degrader / Unkown
HY-153881 KRAS G12C degrader-1 / Unkown
HY-153899 KRAS G12C inhibitor 59 Inhibitor / Unkown
HY-153940 SOS1/KRAS-IN-1 Inhibitor / Unkown
HY-153944 KRAS G12C inhibitor 60 Inhibitor / Unkown
HY-156363 K-Ras-IN-2 Inhibitor / Unkown
HY-156528 pan-KRAS-IN-4 Inhibitor / Unkown
HY-156549 KRAS G12C inhibitor 61 Inhibitor / Unkown
HY-156555 pan-KRAS-IN-3 / Unkown
HY-156671B RMC-4998 TFA 99.02% Unkown
HY-157458 PDEδ autophagic degrader 1 / Unkown
HY-158701 KRAS G12D inhibitor 23 Inhibitor / Unkown
HY-158703 KRAS G12D inhibitor 24 Inhibitor / Unkown
HY-159163 KRASG12C IN-12 Inhibitor / Unkown
HY-159473 K-Ras-IN-3 Inhibitor / Unkown
HY-159475 KRAS inhibitor-25 Inhibitor / Unkown
HY-159476 KRAS inhibitor-26 Inhibitor / Unkown
HY-159611 KRAS G12C inhibitor 68 Inhibitor / Unkown
HY-160220S KRAS inhibitor-23 Inhibitor / Unkown
HY-160445 KRAS G12D inhibitor 19 Inhibitor / Unkown
HY-161173 PROTAC SOS1 degrader-5 / Unkown
HY-161234 KRAS ligand 3 Ligand / Unkown
HY-161236 KRAS ligand 4 Inhibitor / Unkown
HY-161450 LHF418 Inhibitor / Unkown
HY-161654 PROTAC SOS1 degrader-10 / Unkown
HY-161714 HH0043 Inhibitor / Unkown
HY-162281 PROTAC SOS1 degrader-6 / Unkown
HY-162321 ZINC57632462 Inhibitor / Unkown
HY-162366 KRAS G12D inhibitor 20 Inhibitor / Unkown
HY-162439 pan-KRAS-IN-6 Inhibitor / Unkown
HY-162440 pan-KRAS-IN-7 Inhibitor / Unkown
HY-162441 pan-KRAS-IN-8 Inhibitor / Unkown
HY-162442 pan-KRAS-IN-9 Inhibitor / Unkown
HY-162443 pan-KRAS-IN-10 Inhibitor / Unkown
HY-162444 KRAS G12D inhibitor 22 Inhibitor / Unkown
HY-162445S KRASG12D-IN-3-d3 / Unkown
HY-162446 pan-KRAS-IN-13 Inhibitor / Unkown
HY-162873 MEK/RAF-IN-1 Inhibitor / Unkown
HY-162971 KRAS inhibitor-33 Inhibitor / Unkown
HY-162974 KRAS inhibitor-34 Inhibitor / Unkown
HY-162976 KRAS inhibitor-35 Inhibitor / Unkown
HY-162983 KRAS inhibitor-36 Inhibitor / Unkown
HY-163488 KRASG12D-IN-4 Inhibitor / Unkown
HY-163489 pan-KRAS-IN-15 Inhibitor / Unkown
HY-163636 Deltaflexin3 Inhibitor / Unkown
HY-163720 KRAS G12C inhibitor 63 / Unkown
HY-163880 EGFR-IN-119 Inhibitor / Unkown
HY-164492 LSN3074753 Inhibitor / Unkown
HY-164632 KRAS inhibitor-32 Inhibitor / Unkown
HY-164645 pan-KRAS-IN-16 Inhibitor / Unkown
HY-168013 KRASG12C IN-14 Inhibitor / Unkown
HY-168055 (S)-Deoxy-thalidomide / Unkown
HY-168056 KRAS ligand 5 Degrader / Unkown
HY-168076 (S)-Deoxy-thalidomide-2,7-diazaspiro[3.5]nonane-CH2-Me-PIP-Boc / Unkown
HY-168442 KRAS inhibitor-40 Inhibitor / Unkown
HY-168512 BRAFV600E-IN-1 Inhibitor / Unkown
HY-168514 SOS1/EGFR-IN-2 Inhibitor / Unkown
HY-168577 KRAS G12D inhibitor 25 / Unkown
HY-168637 SIAIS562055 Inhibitor / Unkown
HY-168672 E3 Ligase Ligand-linker Conjugate 133 / Unkown
HY-168678 PROTAC K-Ras Degrader-6 Inhibitor / Unkown
HY-168700 KRAS G12D ligand-2 / Unkown
HY-168919 KRASG12C IN-16 / Unkown
HY-169311 KRAS inhibitor-37 Inhibitor / Unkown
HY-169312 KRAS inhibitor-38 Inhibitor / Unkown
HY-170550 KRAS G12C inhibitor 69 Inhibitor / Unkown
HY-170785 pan-KRAS-IN-17 Inhibitor / Unkown
HY-171581 KRAS G12D-IN-27 Inhibitor / Unkown
HY-172221 SOS1-IN-18 Inhibitor / Unkown
HY-172626 KRAS G12D inhibitor 28 Inhibitor / Unkown
HY-172919 PDEδ/NAMPT IN-1 / Unkown
HY-173047 KRASG12C IN-15 Inhibitor / Unkown
HY-173250 YN14-H / Unkown
HY-173252 KRASG12C ligand-1 Inhibitor / Unkown
HY-173329 KRAS-IN-41 Inhibitor / Unkown
HY-173341 SOF-436 Inhibitor / Unkown
HY-173632A AMG410 diTFA Inhibitor / Unkown
HY-174088 CDK4/6/BRD4-IN-2 / Unkown
HY-174243 KRASG12D-IN-5 Inhibitor / Unkown
HY-174254 AKT-IN-28 / Unkown
HY-174261 KRAS-IN-5 Inhibitor / Unkown
HY-174379 KRAS IN-44 / Unkown
HY-174851 KRAS G12C-IN-70 Inhibitor / Unkown
HY-175025 CH091138 / Unkown
HY-175144 KRASG12D-IN-6 Inhibitor / Unkown
HY-175244 SOS1-IN-20 Inhibitor / Unkown
HY-175265 PQ32 / Unkown
HY-175326 SOS1-IN-21 Inhibitor / Unkown
HY-175419 TBIA Inhibitor / Unkown
HY-175529 KRASG12D-IN-7 / Unkown
HY-175560 SOS1-IN-22 Inhibitor / Unkown
HY-175673 LCB-2151 / Unkown
HY-175860 KRAS G12D ligand-Linker Conjugate 2 / Unkown
HY-175870A (7R)-Eras-4001 Inhibitor / Unkown
HY-176170 SOS1-IN-19 Inhibitor / Unkown
HY-176250 KRAS-IN-43 Inhibitor / Unkown
HY-176341S KRAS 2B G13D mutant, Arg-13C6,15N4, Lys-13C6,15N2 / Unkown
HY-176342S KRAS 2B Q61H mutant, Arg-13C6,15N4, Lys-13C6,15N2 / Unkown
HY-176353S KRAS 2B G13C mutant, Arg-13C6,15N4, Lys-13C6,15N2 / Unkown
HY-176354S KRAS 2B G12V mutant, Arg-13C6,15N4, Lys-13C6,15N2 / Unkown
HY-176355S KRAS 2A, U-15N / Unkown
HY-176356S KRAS 2B, Arg-13C6,15N4, Lys-13C6,15N4 / Unkown
HY-176357S KRAS 2B G12R mutant, Arg-13C6,15N4, Lys-13C6,15N2 / Unkown
HY-176358S KRAS 2B G12C mutant, Arg-13C6,15N4, Lys-13C6,15N2 / Unkown
HY-176359S KRAS 2B G12D mutant, Arg-13C6,15N4, Lys-13C6,15N2 / Unkown
HY-176419 KRAS inhibitor-42 Inhibitor / Unkown
HY-176490 pan-KRAS ligand 3 / Unkown
HY-176491 Alkyne-pyrazine-O-piperidine-(1-methylcyclopropyl)methanol Chemical / Unkown
HY-176492 E3 Ligase Ligand-linker Conjugate 193 Chemical / Unkown
HY-176787 KRAS G12C Ligand-Linker Conjugates 1 Inhibitor / Unkown
HY-176792A (R)-ACBI-4 Degrader / Unkown
HY-176870 KRAS-IN-42 Inhibitor / Unkown
HY-176917 E3 ligase Ligand 76 / Unkown
HY-176918 K-Ras ligand-Linker Conjugate 8 Degrader / Unkown
HY-178042 SS-3091 Inhibitor / Unkown
HY-178044 SOS1-IN-24 Inhibitor / Unkown
HY-178224 Morindone / Unkown
HY-178497 ZJK-807 / Unkown
HY-178501 KRAS-IN-45 Inhibitor / Unkown
HY-178502 KRAS-IN-46 Inhibitor / Unkown
HY-178873 PROTAC K-Ras Degrader-7 Degrader / Unkown
HY-178874 E3 ligase Ligand 75 / Unkown
HY-178875 Nrf2 activator-22 Activator / Unkown
HY-178888 Nrf2 ligand-Linker Conjugate 2 / Unkown
HY-178910 Mcl-1-IN-20 / Unkown
HY-179058 JOSD2-IN-1 Inhibitor / Unkown
HY-179253 KRAS-IN-47 Inhibitor / Unkown
HY-179254 Mal-L-Dap(Boc, t-BuOAc)-Pfp Ester / Unkown
HY-179300 KRAS-IN-48 free base Inhibitor / Unkown
HY-179300A KRAS-IN-48 Inhibitor / Unkown
HY-179318 KRAS G12D-IN-32 Inhibitor / Unkown
HY-179403 KRASG12C IN-17 Inhibitor / Unkown
HY-179404 KRASG12C IN-18 Inhibitor / Unkown
HY-179414 KRAS G12D-IN-34 Inhibitor / Unkown
HY-179443 SOS1-IN-25 Inhibitor / Unkown
HY-179452 KRAS G13D-IN-2 Inhibitor / Unkown
HY-179480 G-quadruplex ligand 4 / Unkown
HY-179484 KRASG12C IN-19 Inhibitor / Unkown
HY-179534 G13Ci-22 Inhibitor / Unkown
HY-179536 KRAS-IN-49 Inhibitor / Unkown
HY-179702 KD36 / Unkown
HY-180298 KRAS G12C-IN-71 Inhibitor / Unkown
HY-180607 KRAS-IN-50 Inhibitor / Unkown
HY-180885S KRAS G12D-IN-35 Inhibitor / Unkown
HY-180920 KRAS G12D-IN-36 Inhibitor / Unkown
HY-181020 Deltafluorine Inhibitor / Unkown
HY-181284 BYBC-1 / Unkown
HY-181420 (S,R,S)-BBO-11818 Inhibitor / Unkown
HY-181570 KRAS G12C-IN-73 / Unkown
HY-181704 KRAS-IN-54 Inhibitor / Unkown
HY-181716 KRAS G12C-IN-74 / Unkown
HY-181728 MS243 Degrader / Unkown
HY-181733 KRAS G12D ligand-3 Degrader / Unkown
HY-181734 E3 Ligase Ligand-linker Conjugate 224 / Unkown
HY-181807 SOS1/KRAS-IN-2 / Unkown
HY-181883 KRAS-IN-55 Inhibitor / Unkown
HY-181889 KRAS G12C-IN-75 Inhibitor / Unkown
HY-181913 KRAS G12C-IN-76 Inhibitor / Unkown
HY-181964 KRAS G12C-IN-77 / Unkown
HY-181965 KRAS G12C-IN-78 Inhibitor / Unkown
HY-182044 MRTX849-amide-C4-(o)-carborane / Unkown
HY-182055 Anticancer agent 309 / Unkown
HY-182241 JR4-187 / Unkown
HY-182411 KRAS-IN-56 Inhibitor / Unkown
HY-182706 NSC 373981 Inhibitor / Unkown
HY-182749 KRAS-IN-58 Inhibitor / Unkown
HY-182883 KRASG12C IN-20 Inhibitor / Unkown
HY-182994 pan-KRAS-IN-20 Inhibitor / Unkown
HY-183068 AP4-43 Inhibitor / Unkown
HY-183355 KRAS G12D-IN-37 / Unkown
HY-183365 SL43 Inhibitor / Unkown
HY-183625 PCA-IN-1 Inhibitor / Unkown
HY-183645 KRAS G12C-IN-79 Inhibitor / Unkown
HY-183741 VVD-844 Inhibitor / Unkown
HY-185205 VVD-484 Inhibitor / Unkown
HY-185217 PPI stabilizer-1 / Unkown
HY-186024 KRAS-IN-51 Inhibitor / Unkown
HY-186086 RM-041 Inhibitor / Unkown
HY-18652A Avutometinib potassium Inhibitor / Unkown
HY-19315 SML-8-73-1 Inhibitor / Unkown
HY-N8387 Neogrifolin Inhibitor / Unkown
HY-P10847 KS-58 Inhibitor / Unkown
HY-P11356 KRAS G12V Peptide Activator / Unkown
HY-P11357 KRAS G12C Peptide Activator / Unkown
HY-P2265 SAH-SOS1A Inhibitor / Unkown
HY-P3129 KRAS G13D peptide, 25 mer / Unkown
HY-P3430 JM3A / Unkown
HY-RS07427 Kras Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09558 NRAS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W1126467 RAS-IN-5 Inhibitor / Unkown
HY-W556631 LZTR1-KRAS modulator 1 Activator / Unkown
HY-112541 21-Hydroxyoligomycin A Inhibitor / Unkown
HY-114277S2 Sotorasib-d3 Inhibitor / Unkown
HY-120885 (+)-Oxanthromicin Modulator / Unkown
HY-121459 Neoantimycin Modulator / Unkown
HY-149710 POP-3MB Inhibitor / Unkown
HY-157067 KRAS G12C inhibitor 62 Inhibitor / Unkown
HY-161655 SOS1 Ligand intermediate-5 Inhibitor / Unkown
HY-161656 PIP-C-3-Azaspiro[5.5]undecane-boc / Unkown
HY-164389 SML-10-70-1 / Unkown
HY-164427 SHP2-IN-31 Inhibitor / Unkown
HY-164513 NHTD Inhibitor / Unkown
HY-164529 SJ-C1044 Inhibitor 98.63% Unkown
HY-168075 Boc-PIP-Me-CH2-2,7-diazaspiro[3.5]nonane / Unkown
HY-168671 pan-KRAS ligand 1 Inhibitor / Unkown
HY-168680 E3 Ligase Ligand-linker Conjugate 135 / Unkown
HY-42936 ARS-1620 intermediate / Unkown
HY-W142207 (E)-3-Chloroacrylic acid / Unkown
HY-W335254 Deltarasin trihydrochloride Inhibitor / Unkown
HY-W999529 KRAS G12C degrader-2 / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991571 GC1118 Inhibitor / Unkown
HY-P991743 Anti-KRAS Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens KRAS NCBI NCBI:3845