AGER - advanced glycosylation end-product specific receptor Gene

Also Known as RAGE; sRAGE; SCARJ1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 177

About AGER

Cytogenetic location: 6p21.32 Genomic coordinates (GRCh38): 6:32,180,969-32,184,253 (from NCBI)

This gene has 13 transcripts (splice variants), 1 gene allele, 170 orthologues and 3 paralogues. Biased expression in lung (RPKM 397.6) and spleen (RPKM 11.0).

Summary

The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with Other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]

AGER Products (9)

mRNA	Protein	Name
NM_001136.5	NP_001127.1	advanced glycosylation end product-specific receptor isoform 1 precursor
NM_001206929.2	NP_001193858.1	advanced glycosylation end product-specific receptor isoform 2 precursor
NM_001206932.2	NP_001193861.1	advanced glycosylation end product-specific receptor isoform 3 precursor
NM_001206934.2	NP_001193863.1	advanced glycosylation end product-specific receptor isoform 4 precursor
NM_001206936.2	NP_001193865.1	advanced glycosylation end product-specific receptor isoform 5 precursor
NM_001206940.2	NP_001193869.1	advanced glycosylation end product-specific receptor isoform 6 precursor
NM_001206954.2	NP_001193883.1	advanced glycosylation end product-specific receptor isoform 8 precursor
NM_001206966.2	NP_001193895.1	advanced glycosylation end product-specific receptor isoform 6 precursor
NM_172197.3	NP_751947.1	advanced glycosylation end product-specific receptor isoform 7 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables S100 protein binding	IPI IPI: Inferred from physical interaction	15033494	GOA
enables amyloid-beta binding	IDA IDA: Inferred from direct assay	29518356	GOA
enables amyloid-beta binding	IPI IPI: Inferred from physical interaction	22406537	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	24119142	GOA
enables molecular adaptor activity	EXP EXP: Inferred from Experiment	22194616	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16061848	GOA
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	29518356	GOA
enables signaling receptor activity	IMP IMP: Inferred from mutant phenotype	15457210	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in astrocyte activation	IGI IGI: Inferred from genetic interaction	15457210	GOA
involved in glucose mediated signaling pathway	IDA IDA: Inferred from direct assay	25689357	GOA
involved in learning or memory	IGI IGI: Inferred from genetic interaction	15457210	GOA
involved in microglial cell activation	IGI IGI: Inferred from genetic interaction	15457210	GOA
involved in negative regulation of interleukin-10 production	IDA IDA: Inferred from direct assay	22473704	GOA
involved in negative regulation of long-term synaptic depression	IGI IGI: Inferred from genetic interaction	20739563	GOA
involved in negative regulation of long-term synaptic potentiation	IGI IGI: Inferred from genetic interaction	15457210	GOA
involved in neuron projection development	IGI IGI: Inferred from genetic interaction	10391939	GOA
involved in positive regulation of ERK1 and ERK2 cascade	IGI IGI: Inferred from genetic interaction	15457210	GOA
involved in positive regulation of JNK cascade	IGI IGI: Inferred from genetic interaction	20739563	GOA
involved in positive regulation of NF-kappaB transcription factor activity	IDA IDA: Inferred from direct assay	10391939	GOA
involved in positive regulation of activated T cell proliferation	IMP IMP: Inferred from mutant phenotype	15944249	GOA
involved in positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	IGI IGI: Inferred from genetic interaction	22406537	GOA
involved in positive regulation of dendritic cell differentiation	IMP IMP: Inferred from mutant phenotype	15944249	GOA
involved in positive regulation of heterotypic cell-cell adhesion	IGI IGI: Inferred from genetic interaction	11078691	GOA
involved in positive regulation of interleukin-12 production	IMP IMP: Inferred from mutant phenotype	15944249	GOA
involved in positive regulation of monocyte extravasation	IMP IMP: Inferred from mutant phenotype	11078691	GOA
involved in positive regulation of non-canonical NF-kappaB signal transduction	IGI IGI: Inferred from genetic interaction	15457210	GOA
involved in positive regulation of p38MAPK cascade	IGI IGI: Inferred from genetic interaction	20739563	GOA
involved in positive regulation of protein phosphorylation	IGI IGI: Inferred from genetic interaction	15457210	GOA
involved in regulation of CD4-positive, alpha-beta T cell activation	IDA IDA: Inferred from direct assay	22473704	GOA
involved in regulation of T cell mediated cytotoxicity	IDA IDA: Inferred from direct assay	22473704	GOA
involved in regulation of spontaneous synaptic transmission	IGI IGI: Inferred from genetic interaction	15457210	GOA
involved in transport across blood-brain barrier	IDA IDA: Inferred from direct assay	23973487	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in apical plasma membrane	IDA IDA: Inferred from direct assay	26005850	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AGER Protein Structure

Ig_2

C2-set_2

Ig_2

0
100
200
300
404 a.a.

Protein Preferred Names	Protein Names
advanced glycosylation end product-specific receptor	receptor for advanced glycation end-products

AGER Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	AGER	Q15109	TTMP	Homo sapiens	Q5BVD1	Validated Y2H	32296183
Intra	AGER	Q15109	MAPKAPK5	Homo sapiens	Q8IW41	PLA	26758977
Intra	AGER	Q15109	MAPKAPK5	Homo sapiens	Q8IW41	IF	26758977
Intra	AGER	Q15109	MAPKAPK5	Homo sapiens	Q8IW41	Anti Bait CoIP	26758977
Intra	AGER	Q15109	MAPKAPK5	Homo sapiens	Q8IW41	Y2H	26758977
Intra	AGER	Q15109	MAPKAPK5	Homo sapiens	Q8IW41	Anti Tag CoIP	26758977
Intra	AGER	Q15109	MAPKAPK5	Homo sapiens	Q8IW41	SPR	26758977
Intra	AGER	Q15109	BDNF	Homo sapiens	P23560-2	Y2H Array	32814053
Intra	AGER	Q15109	BDNF	Homo sapiens	P23560-2	Validated Y2H	32814053
Intra	AGER	Q15109	BDNF	Homo sapiens	P23560-2	Y2H Pooling	32814053
Intra	AGER	Q15109	C2orf15	Homo sapiens	Q8WU43	Validated Y2H	32814053
Intra	AGER	Q15109	C2orf15	Homo sapiens	Q8WU43	Y2H Array	32814053
Intra	AGER	Q15109	C2orf15	Homo sapiens	Q8WU43	Y2H Pooling	32814053
Intra	AGER	Q15109	S100B	Homo sapiens	P04271	ELISA	17660747
Intra	AGER	Q15109	S100B	Homo sapiens	P04271	SPR	17726019
Intra	AGER	Q15109	S100B	Homo sapiens	P04271	Filter Binding	17660747
Intra	AGER	Q15109	PRKCZ	Homo sapiens	Q05513	Anti Tag CoIP	21829704
Intra	AGER	Q15109	PRKCZ	Homo sapiens	Q05513	Anti Bait CoIP	21829704
Intra	AGER	Q15109	DIAPH1	Homo sapiens	O60610	Pull Down	18922799
Intra	AGER	Q15109	S100B	Homo sapiens	P04271	SPR	17660747
Intra	AGER	Q15109	DIAPH1	Homo sapiens	O60610	Anti Tag CoIP	18922799
Intra	AGER	Q15109	DIAPH1	Homo sapiens	O60610	Y2H	18922799
Intra	AGER	Q15109	MIER1	Homo sapiens	Q8N108-16	Y2H Array	32814053
Intra	AGER	Q15109	MIER1	Homo sapiens	Q8N108-16	Y2H Pooling	32814053
Intra	AGER	Q15109	MIER1	Homo sapiens	Q8N108-16	Validated Y2H	32814053
Intra	AGER	Q15109	CMTM7	Homo sapiens	Q96FZ5	Validated Y2H	32296183
Intra	AGER	Q15109	EGFR	Homo sapiens	P00533	Anti Bait CoIP	16954185
Intra	AGER	Q15109	EGFR	Homo sapiens	P00533	Anti Tag CoIP	16954185
Intra	AGER	Q15109	HMGB1	Homo sapiens	P09429	SPR	24474694
Intra	AGER	Q15109	TIRAP	Homo sapiens	P58753	Anti Bait CoIP	21829704
Intra	AGER	Q15109	TIRAP	Homo sapiens	P58753	Anti Tag CoIP	21829704
Intra	AGER	Q15109	CREB3	Homo sapiens	O43889-2	Validated Y2H	25910212
Intra	AGER	Q15109	CREB3	Homo sapiens	O43889-2	Y2H Bait-Prey Pool	25910212
Intra	AGER	Q15109	CREB3	Homo sapiens	O43889-2	Y2H Array	25910212
Cross	AGER	Q15109	Egfr	Mus musculus	Q01279	Anti Bait CoIP	16954185
Cross	AGER	Q15109	Egfr	Mus musculus	Q01279	Anti Tag CoIP	16954185
Intra	AGER	Q15109	TTR	Homo sapiens	P02766	Competition Binding	16716307
Intra	AGER	Q15109	S100P	Homo sapiens	P25815	Anti Bait CoIP	16061848

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant AGER Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7467	AGER Protein, Human (HEK293, His)	Q15109 (A23-A344)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P74604	AGER Protein, Human (HEK293, hFc)	Q15109 (Q24-A344)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P74605	AGER Protein, Human (HEK293)	Q15109 (A23-A344)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P700146AF	Animal-Free AGER Protein, Human (His)	Q15109 (A23-S300)	≥ 95%, as determined by reducing SDS-PAGE.

AGER Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P81086	RAGE Antibody	WB, IHC-P, IHC-F, ICC/IF, FC	Human, Mouse, Rat
HY-P81086A	RAGE Antibody(YA3549)	WB, IHC-P, IF-Tissue, mIHC	Human, Mouse, Rat
HY-P86096	RAGE Antibody (YA5788)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
HY-P86924	RAGE Antibody(YA6617)	mIHC	Mouse

Related Diseases

Diseases	Alias
Diabetic Angiopathy	Diabetic Angiopathies Diabetic Peripheral Angiopathy Diabetic Vascular Disorder
Diabetic Neuropathy	Diabetic Neuropathies
Hyperglycemia
Leukostasis
Microvascular Complications Of Diabetes 5	Diabetic Retinopathy Microvascular Complications Of Diabetes, Susceptibility To, 5 MVCD5 Retinopathy, Diabetic Diabetic Nephropathy Retinopathy, Diabetic, Susceptibility To Retinal Abnormality - Diabetes-Related
Myocardial Infarction	Heart Attack Myocardial Infarction, Susceptibility To Myocardial Infarction 1 Myocardial Infarction, Protection Against Myocardial Infarction, Decreased Susceptibility To Myocardial Infarction, Decreased Myocardial Infarct MCI1 Premature Myocardial Infarction Myocardial Infarction, Susceptibility To, Type 1
Vascular Disease	Vascular Diseases Aneurysm Spinal Cord Ischemia Vascular Anomaly Spinal Cord Vascular Diseases Vascular Tissue Disease
Kidney Disease	Renal Failure Kidney Failure Kidney Diseases Nephropathy Abnormality Of The Kidney Impaired Renal Function Disease Renal Anomaly Kidney Dysfunction Renal Disease Nephropathies Renal Failure Adverse Event Abnormal Renal Function
Amyloidosis	Amyloid Disease Amyloid Amyloid Degeneration Amyloidosis Nos Amyloid Deposition Amyloid Infiltration Idiopathic Amyloidosis Hyaloid Degeneration Lardaceous Degeneration
Diabetes Mellitus	Diabetes
Atherosclerosis Susceptibility	Atherosclerosis Atherosclerosis, Susceptibility To ATHS Atherogenic Lipoprotein Phenotype Alp Arteriosclerosis
Granulomatosis With Polyangiitis	GPA Wegener Granulomatosis Wegener Granulomatosis, Formerly Midline Granulomatosis Wg, Formerly Necrotizing Respiratory Granulomatosis Wg Wegeners Granulomatosis Pauci-Immune Glomerulonephritis Associated With Granulomatosis With Polyangiitis
Brain Edema	Cerebral Edema Intracranial Swelling Wet Brain
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Type 2 Diabetes Diabetes Mellitus, Non-Insulin-Dependent T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes
Microvascular Complications Of Diabetes 3	Diabetic Nephropathy Microvascular Complications Of Diabetes, Susceptibility To, 3 MVCD3 Nephropathy, Diabetic Nephropathy, Diabetic, Susceptibility To End-Stage Renal Disease, Diabetic End-Stage Renal Disease, Diabetic, Susceptibility To Diabetic End-Stage Renal Disease Diabetic Nephropathies
Dementia	Dementias Presenile Dementia Alzheimer Type Dementia Alzheimer Sclerosis Alzheimer Disease Dementia Alzheimer Dementia Primary Degenerative Alzheimer Type Dementia End Stage Alzheimer'S Dementia Alzheimer'S Type Atypical Dementia Alzheimer Type Presenile Dementia Early Onset Alzheimer Dementia Dementia In Alzheimer Disease Type 2 Dementia In Alzheimer Disease With Early Onset Early Onset Alzheimer Type Dementia, Uncomplicated Primary Degenerative Alzheimer Type Dementia, Early Onset Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated Alzheimer Disease Dementia With Early Onset Presenile Sclerosis Presenile Brain Sclerosis Presenile Alzheimer Brain Sclerosis Late Onset Alzheimer Dementia Dementia In Alzheimer Disease Type 1 Dementia In Alzheimer Disease With Late Onset Primary Degenerative Alzheimer Type Dementia, Late Onset Sdat - [Senile Dementia, Alzheimer Type] Alzheimer Disease Dementia With Late Onset Late Onset Alzheimer Brain Sclerosis Senile Alzheimer Brain Disease Senile Alzheimer Brain Sclerosis Senile Primary Degenerative Alzheimer Type Dementia Senile Dementia Of The Alzheimer Type Arteriosclerotic Dementia Strategic-Infarct Dementia Post Stroke Dementia Vascular Cognitive Impairment Vascular Dementia Dementia Of The Lewy Body Type Dementia With Lewy Bodies Sdlt - [Senile Dementia Of The Lewy Body Type] Senile Dementia Of The Lewy Body Type Alcohol-Related Dementia Alcoholic Dementia Nos Alcohol-Induced Dementia Alcoholic Brain Syndrome Chronic Alcoholic Brain Syndrome Alcohol Dementia Late Onset Alcoholic Psychosis Residual And Late-Onset Alcohol-Induced Psychotic Disorder Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder Late-Onset Psychoactive Substance-Induced Psychotic Disorder Inhalant Dementia Volatile Solvents Dementia Dementia In Paralysis Agitans Pdd - [Parkinson Disease Dementia] Dementia Syndrome Of Parkinson Disease Dementia In Parkinson Disease Parkinson Related Dementia Dementia In Huntington Chorea Hiv - [Human Immunodeficiency Virus] Dementia Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex Aids Related Dementia Dementia Due To Niacin Deficiency
Pelvic Organ Prolapse	Rectal Prolapse Pelvic Organ Prolapse, Susceptibility To, 1 Pelvic Organ Prolapse, Susceptibility To Prolapse Of Vagina And Rectum Vaginal Prolapse Pelvic Organ Prolapse 1 Procidentia, Rectum Prolapse Of Rectal Mucosa Procidentia Of Rectum Rectal Mucosa Prolapse Rectum Prolapse Procidentia Rectum Rp - [Rectal Prolapse] Male Proctocele Male Rectocele Proctoptosis Female Genital Prolapse Female Prolapse Incompetence Of Pelvic Fundus Relaxation Of Perineum Deficiency Of Perineum
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Pre-Eclampsia	Preeclampsia Gestational Hypertension Hypertension Induced By Pregnancy Pre-Eclamptic Toxaemia Pregnancy Associated Hypertension Proteinuric Hypertension Of Pregnancy Hypertension, Pregnancy-Induced, Susceptibility To Preeclampsia/Eclampsia Pregnancy Toxemia Toxaemia Of Pregnancy Gestational Proteinuric Hypertension Pregnancy-Induced Hypertension Toxemia Of Pregnancy Preeclampsia, Susceptibility To Transient Hypertension Of Pregnancy Gestational [Pregnancy-Induced] Hypertension Without Significant Proteinuria Gestational Hypertension Nos Mild Proteinuric Hypertension Of Pregnancy Pih - [Pregnancy-Induced Hypertension] Pregnancy-Induced Hypertension Nos Gestational [Pregnancy-Induced] Hypertension With Significant Proteinuria Pe - [Pre-Eclampsia] Pre-Eclampsia Nos Pre-Eclamptic Nos Pregnancy Pre-Eclampsia Puerperal Pre-Eclampsia Pre-Eclampsia Toxaemia Toxaemia In Pregnancy Pet - [Pre-Eclamptic Toxaemia] Maternal Toxaemia
Cardiomyopathy, Familial Hypertrophic, 6	Hypertrophic Cardiomyopathy 6 CMH6 Familial Hypertrophic Cardiomyopathy With Wolff-Parkinson-White Syndrome Cardiomyopathy, Familial Hypertrophic 6 Cardiomyopathy, Hypertrophic 6 Cardiomyopathy, Hypertrophic, Familial, Type 6
Cardiovascular System Disease	Abnormality Of The Cardiovascular System Cardiovascular Disease Disease Of Subdivision Of Hemolymphoid System Disorder Of Cardiovascular System Cardiovascular Diseases
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Heart Malformation Congenital Anomaly Of Heart Heart Defect Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Anomaly Coronary Artery Disease, Susceptibility To Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Schizophrenia	SCZD Schizophrenia With Or Without An Affective Disorder Schizophrenia 12 Schizophrenia, Susceptibility To Schizophrenia-1 Dementia Praecox Schizophrenia 1
Partial Third-Nerve Palsy	Partial Third Nerve Palsy Third Nerve Palsy With Pupil Sparing Third Or Oculomotor Nerve Palsy, Partial Oculomotor Nerve Diseases Oculomotor Nerve Paralysis
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset Obesity , Susceptibility To BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To Cryptogenic Fibrosing Alveolitis ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (13)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B0146	Verteporfin		99.58%	Yes
HY-16561	Resveratrol		99.95%	Yes
HY-147080	Avacincaptad pegol sodium	Inhibitor	94.64%	Unkown
HY-B0167A	Sodium Salicylate		99.99%	Yes
HY-W012382	N-Acetyl-L-tyrosine		99.48%	Unkown
HY-109561	Pegaptanib sodium	Inhibitor	90.51%	Unkown
HY-17549	Adrafinil	Agonist	99.85%	Unkown
HY-148457	Avacincaptad pegol	Inhibitor	92.50%	Unkown
HY-B0897	Bisoctrizole		98.0%	Unkown
HY-14892	Gemigliptin	Inhibitor	/	Unkown
HY-13995	Sevelamer	Inhibitor	/	Unkown
HY-185390	Verteporfin liposome	Inhibitor	/	Unkown
HY-B0146R	Verteporfin (Standard)		/	Unkown

Inhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-108801	Aflibercept	Inhibitor	97.90%	Unkown
HY-P99116	Faricimab	Inhibitor	97.97%	Unkown

Clinical Phase

Bioactive Molecules (39)

Cat. No.	Product Name	Effect	Purity	Phase
HY-W004260	Arachidic acid		99.94%	Phase 4
HY-N0160	Kinetin		99.76%	Phase 4
HY-I0626	Cytosine		99.99%	Phase 4
HY-P3252A	Pegcetacoplan acetate	Inhibitor	99.92%	Phase 3
HY-W013494	L-Carnosine		99.95%	Phase 3
HY-106024B	Alagebrium chloride	Inhibitor	99.82%	Phase 3
HY-B1745	Pyridoxylamine		99.91%	Phase 3
HY-19720A	Emixustat hydrochloride	Inhibitor	99.29%	Phase 3
HY-19720	Emixustat		98.00%	Phase 3
HY-116098	Anecortave desacetate		98.36%	Phase 3
HY-109118A	Masupirdine mesylate	Antagonist	99.62%	Phase 3
HY-109118	Masupirdine free base	Antagonist	/	Phase 3
HY-153484	Bevasiranib	Inhibitor	/	Phase 3
HY-112499	Menaquinone-7	Activator	98.51%	Phase 2
HY-128850	N-Acetyl-D-mannosamine		99.99%	Phase 2
HY-128973	Pyropheophorbide-a		98.0%	Phase 2
HY-P3204	POT-4	Inhibitor	98.88%	Phase 2
HY-132806	Alogabat	Agonist	99.93%	Phase 2
HY-P5285	Lunasin	Inhibitor	98.22%	Phase 2
HY-10186	TG 100801	Inhibitor	98.61%	Phase 2
HY-W250163	NAD+ lithium		99.49%	Phase 2
HY-W701069	Isomyosmine		97.38%	Phase 2
HY-112499R	Menaquinone-7 (Standard)		98.27%	Phase 2
HY-153484A	Bevasiranib sodium	Inhibitor	97.68%	Phase 2
HY-177668A	Umedaptanib pegol sodium	Inhibitor	/	Phase 2
HY-136788A	ALK4290 dihydrochloride	Inhibitor	/	Phase 2
HY-14564	GTS-21	Agonist	/	Phase 2
HY-150177	Mannose 6 phosphate		/	Phase 2
HY-177668	Umedaptanib pegol	Inhibitor	/	Phase 2
HY-P1930	Risuteganib	Inhibitor	/	Phase 2
HY-P3204A	POT-4 TFA	Inhibitor	/	Phase 2
HY-10187	TG 100801 Hydrochloride	Inhibitor	/	Phase 2
HY-B1041	Aminoguanidine hydrochloride		≥98.0%	Phase 1
HY-W050154	Kojic acid	Inhibitor	99.99%	Phase 1
HY-N1420A	Rhamnose monohydrate		99.95%	Phase 1
HY-15114	S 17092	Inhibitor	99.78%	Phase 1
HY-137557	Florzolotau	Ligand	/	Phase 1
HY-16387	PF 00337210	Inhibitor	/	Phase 1
HY-19692	Itasetron	Antagonist	/	Phase 1

Inhibitory Antibodies (8)

Cat. No.	Product Name	Effect	Purity	Phase
HY-108801A	Aflibercept (VEGF Trap)	Inhibitor	97.66%	Phase 4
HY-P99576	Tarcocimab	Inhibitor	98.35%	Phase 3
HY-P99298	Lampalizumab	Inhibitor	99.46%	Phase 3
HY-P991416	BAT5906	Inhibitor	/	Phase 3
HY-P991418	MW02	Inhibitor	/	Phase 3
HY-P99629	Galegenimab	Inhibitor	99.91%	Phase 2
HY-P991535	PMN310	Inhibitor	/	Phase 1
HY-P991415	ASKG-712	Antagonist	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (355)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-112879	Mito-TEMPO		99.19%	Unkown
HY-N0088	Apocynin	Inhibitor	99.94%	Unkown
HY-131042	NNMTi	Inhibitor	99.70%	Unkown
HY-N1485	Cycloastragenol	Activator	99.95%	Unkown
HY-N0664	Aucubin	Inhibitor	99.98%	Unkown
HY-12688A	Succinyl phosphonate trisodium salt	Inhibitor	98.0%	Unkown
HY-120912	Gingerenone A	Activator	99.95%	Unkown
HY-N0568	Madecassoside		99.58%	Unkown
HY-N0033	Poliumoside	Inhibitor	99.69%	Unkown
HY-147313	TH10785	Activator	99.93%	Unkown
HY-103157	PD146176		99.59%	Unkown
HY-NP165	Advanced glycation end products		/	Unkown
HY-W250118	Cephalin form bovine brain	Activator	98.0%	Unkown
HY-16561R	Resveratrol (Standard)		99.95%	Unkown
HY-W015924	2-Hydroxyisobutyric acid		98.0%	Unkown
HY-P0033	Argireline	Inhibitor	99.86%	Unkown
HY-N0295	Protocatechualdehyde	Inhibitor	99.92%	Unkown
HY-N1420	Rhamnose		99.35%	Yes
HY-125623	MitoPerOx		97.41%	Unkown
HY-402361	TERT activator-1		99.91%	Unkown
HY-147059	Dieckol		99.20%	Unkown
HY-126255	SBI-797812	Activator	99.88%	Unkown
HY-W001083	3-Hydroxyphenylacetic acid		99.77%	Unkown
HY-N2072	Crocetin	Inhibitor	98.07%	Unkown
HY-N5135	Liriopesides B		99.92%	Unkown
HY-P2048	MOTS-c (human)		99.90%	Unkown
HY-125944	MitoTEMPO hydrate		98.03%	Unkown
HY-129460	XJB-5-131	Inhibitor	99.9%	Unkown
HY-N2026	Propylparaben		99.96%	Unkown
HY-N9914	D-Psicose	Inhibitor	99.99%	Unkown
HY-11068	SB 239063	Inhibitor	99.49%	Unkown
HY-129380	Fructosyl-lysine		99.86%	Unkown
HY-120380	FeTMPyP	Inhibitor	99.98%	Unkown
HY-P1928	Humanin	Inhibitor	99.73%	Unkown
HY-P2048A	MOTS-c(human) acetate	Activator	99.74%	Unkown
HY-W337672	H-Pro-Hyp-OH		99.0%	Unkown
HY-W003607	3-O-Ethyl-L-ascorbic acid	Inhibitor	99.94%	Unkown
HY-110195	Smurf1-IN-A01		99.81%	Unkown
HY-159062	Goji Extract	Activator	/	Unkown
HY-P1149	Epitalon	Activator	99.63%	Yes
HY-107811	Harmol		99.81%	Unkown
HY-133968	24-Methylenecholesterol		99.78%	Unkown
HY-N0012	Glycitin	Inhibitor	99.71%	Unkown
HY-N2484	Methylnissolin	Inhibitor	99.92%	Unkown
HY-150069	UBX1325		99.16%	Unkown
HY-136093A	Lixumistat acetate		99.88%	Unkown
HY-P1149A	Epitalon TFA	Activator	99.46%	Unkown
HY-N2292	Kinsenoside		99.92%	Unkown
HY-W013573	S-Allyl-L-cysteine	Inducer	98.64%	Unkown
HY-163690	HTRA1-IN-1	Inhibitor	95.28%	Unkown
HY-18740A	Trequinsin hydrochloride	Inhibitor	99.86%	Unkown
HY-N4170	Chebulic acid		99.89%	Unkown
HY-N6818	5,7,4'-Trimethoxyflavone		99.65%	Unkown
HY-W250160	PDRN		90.20%	Unkown
HY-43515	ESI1		99.76%	Unkown
HY-B1745A	Pyridoxylamine dihydrochloride		99.92%	Unkown
HY-101528	IDRA 21	Modulator	99.39%	Unkown
HY-164238	LysoPC(18:3)	Chemical	/	Unkown
HY-P10409	SHLP2		99.09%	Unkown
HY-W016414	Triethyl phosphate		99.95%	Unkown
HY-N0723	Neomangiferin		99.80%	Unkown
HY-N7690	3,5,7,3′,4′-Pentamethoxyflavone	Inhibitor	99.69%	Unkown
HY-137817	BCH001	Inhibitor	98.72%	Unkown
HY-106353	Smilagenin	Agonist	98.0%	Yes
HY-76383	LR-90	Inhibitor	99.24%	Unkown
HY-N4089	Quercetin 3-gentiobioside	Inhibitor	99.56%	Unkown
HY-P5904	Caveolin-1 (82-101) amide (human, mouse, rat)	Inhibitor	99.08%	Unkown
HY-W019724	2,2-Dihydroxyacetic acid	Activator	98.0%	Unkown
HY-W128156	10-Hydroxystearic acid	Agonist	99.94%	Unkown
HY-114988	PGE-M		99.9%	Unkown
HY-12462	WS3		98.70%	Unkown
HY-W020086	2,3-Diaminophenazine		99.84%	Unkown
HY-113303	FAPy-adenine		99.86%	Unkown
HY-128463	N-tert-Butyl-α-phenylnitrone	Inhibitor	99.94%	Unkown
HY-13101	MCOPPB trihydrochloride		99.98%	Unkown
HY-145628	CM398	Ligand	99.85%	Unkown
HY-N1517	Ganoderic acid C2		99.72%	Unkown
HY-N6588	3,4,5-Tricaffeoylquinic acid	Inhibitor	98.71%	Unkown
HY-137967	Genistein 7-β-D-Glucuronide		98.76%	Unkown
HY-66015	Palmitoyl hexapeptide-12		99.17%	Unkown
HY-108036A	(S)-Pro-xylane		99.72%	Unkown
HY-128387	2,3-Butanediol		99.96%	Unkown
HY-129566	Withanolide B		≥99.0%	Unkown
HY-16561S	Resveratrol-d4		99.9%	Unkown
HY-A0299	H-Gly-Pro-Hyp-OH	Inhibitor	99.48%	Unkown
HY-B1169	Timonacic		≥98.0%	Unkown
HY-B1340	Carbadox	Inhibitor	98.0%	Unkown
HY-N3127	Orobol	Inhibitor	99.74%	Unkown
HY-N9914R	D-Psicose (Standard)	Inhibitor	99.89%	Unkown
HY-P0064	Palmitoyl Tetrapeptide-3	Inhibitor	99.18%	Unkown
HY-14892A	Gemigliptin tartrate	Inhibitor	99.52%	Unkown
HY-123936	SR12343	Inhibitor	99.66%	Unkown
HY-136093	Lixumistat hydrochloride		99.25%	Unkown
HY-N0859	Schisanhenol	Inhibitor	99.99%	Unkown
HY-N2217	Rotundic acid		99.41%	Unkown
HY-N2278	Kushenol A	Inhibitor	99.98%	Unkown
HY-B1953	Thiacloprid	Agonist	99.66%	Unkown
HY-DY1073	MitoPerOx (solution)		/	Unkown
HY-134633	Alpha-lipoic acid choline ester chloride		99.72%	Unkown
HY-I0626S2	Cytosine-d2		99.69%	Unkown
HY-154847	WM-662	Inhibitor	99.48%	Unkown
HY-15289	Ciproxifan maleate	Antagonist	99.68%	Unkown
HY-169266	BRD-K56819078	Inhibitor	99.93%	Unkown
HY-N0363	(+)-Columbianetin		99.04%	Unkown
HY-N0757	8-O-Acetylharpagide		99.75%	Unkown
HY-N2485	4'-Methoxyresveratrol		99.48%	Unkown
HY-N2550A	(+)-Coclaurine hydrochloride	Control	99.09%	Unkown
HY-W001288	Indole-4-carboxaldehyde	Activator	99.85%	Unkown
HY-W015616	Benzylacetone	Inhibitor	99.98%	Unkown
HY-W585874	Nε-(Carboxyethyl)lysine	Modulator	99.97%	Unkown
HY-117924	AUTEN-67	Inducer	97.14%	Unkown
HY-110291	A-971432	Agonist	99.31%	Unkown
HY-130221	(25S)-Δ7-Dafachronic acid		96.92%	Unkown
HY-170794	ALT-007	Inhibitor	99.81%	Unkown
HY-N3026	Soyasaponin Ab		99.20%	Unkown
HY-P2096	Hexapeptide-11		99.77%	Unkown
HY-P5220A	Acetyl hexapeptide-1 acetate		99.47%	Unkown
HY-14567	Ciproxifan	Antagonist	99.26%	Unkown
HY-N0857	Deoxyandrographolide	Activator	99.80%	Unkown
HY-N7426	3-Deoxyglucosone		95.0%	Unkown
HY-P1930A	Risuteganib hydrochloride	Inhibitor	98.64%	Yes
HY-14892B	Gemigliptin tartrate hydrate	Inhibitor	99.83%	Unkown
HY-179041	SZ0232		99.25%	Unkown
HY-B0265A	(R)-Nimodipine	Antagonist	99.87%	Unkown
HY-N0363A	(+)-Columbianetin acetate		99.83%	Unkown
HY-NP162	Recombinant Humanized Type XVII Collagen		95.00%	Unkown
HY-P2914	Carnitine acetyltransferase		/	Unkown
HY-P2940	NADase		/	Unkown
HY-P3163	Hexapeptide-9		99.28%	Unkown
HY-P5251	Oligopeptide-68		98.56%	Unkown
HY-130687A	Psicose		99.90%	Unkown
HY-N2026S1	Propylparaben-d4		99.62%	Unkown
HY-W013494S	L-Carnosine-d4		99.84%	Unkown
HY-W747597	Ganglioside GD1b Disodium Salt (Bovine Brain)		98%	Unkown
HY-136093B	Lixumistat		99.33%	Unkown
HY-16467	Squalamine lactate	Inhibitor	98.42%	Unkown
HY-108036	Pro-xylane (30% in water)		98.0%	Unkown
HY-108036B	Pro-xylane		98.0%	Unkown
HY-125931	Unifiram	Activator	99.68%	Unkown
HY-128387S1	2,3-Butanediol-d8		99.28%	Unkown
HY-129380A	Fructosyl-lysine dihydrochloride		95.0%	Unkown
HY-139464	Q134R		99.11%	Unkown
HY-162866	CXM102	Activator	99.36%	Unkown
HY-162904	BPU17		98.16%	Unkown
HY-169265	BRD-K20733377	Inhibitor	99.50%	Unkown
HY-N2947	Boeravinone B	Inhibitor	97.59%	Unkown
HY-N7628	Cassiaside C		99.90%	Unkown
HY-P0099	Pentapeptide-3	Antagonist	99.83%	Unkown
HY-W012382S	N-Acetyl-L-tyrosine-d3		98.44%	Unkown
HY-Y0785	Glyoxal (40% w/w in water)		/	Unkown
HY-P5220	Acetyl hexapeptide-1		99.43%	Unkown
HY-W442049	Hydroxypinacolone retinoate		99.33%	Unkown
HY-11053	S 24795	Agonist	99.66%	Unkown
HY-114653	SRPIN803	Inhibitor	99.70%	Unkown
HY-126487A	H-Arg-Lys-OH TFA		99.86%	Unkown
HY-136688	MI-389	Inhibitor	99.34%	Unkown
HY-155988	Sirtuin modulator 6	Modulator	99.70%	Unkown
HY-173463	Sirtuin modulator 8	Modulator	96.24%	Unkown
HY-178239A	DX-8951 Hydroxy-acid sodium		98.65%	Unkown
HY-P0095	Acetyl tetrapeptide-5	Inhibitor	99.42%	Unkown
HY-P2663	Acetyl tetrapeptide-2		99.70%	Unkown
HY-N13212	Wolfberry Extract		/	Unkown
HY-W089800	trans-2-Nonenal		98.99%	Unkown
HY-107652	AF-DX 384	Antagonist	98.0%	Unkown
HY-124609	CAD031		99.39%	Unkown
HY-132126	SPHINX	Inhibitor	99.87%	Unkown
HY-147108	Mitochondria degrader-1	Inducer	95.10%	Unkown
HY-15492	AG-13958	Inhibitor	99.69%	Unkown
HY-164826	Acetyl zingerone		99.34%	Unkown
HY-186178	CD38-IN-6	Inhibitor	99.96%	Unkown
HY-65008	N-Demethylricinine		99.94%	Unkown
HY-N2284	Sophoflavescenol	Inhibitor	98.78%	Unkown
HY-N3757	(+)-Dihydrorobinetin		98.0%	Unkown
HY-P0104	Palmitoyl tripeptide-38	Activator	99.83%	Unkown
HY-156781	Sirtuin-1 inhibitor 1	Inhibitor	98.09%	Unkown
HY-161088	Anti-aging agent 1	Inhibitor	98.75%	Unkown
HY-164066	Sodium Acetylated Hyaluronate		/	Unkown
HY-17657	Androst-5-enediol sulfate sodium		99.90%	Unkown
HY-113127	L-Tryptophanamide		98.04%	Unkown
HY-133859	M084	Inhibitor	/	Unkown
HY-137557A	(E/Z)-Florzolotau	Ligand	98.01%	Unkown
HY-145486	1-Arachidonoyl-sn-glycerol 3-phosphate ammonium		/	Unkown
HY-153917	CRT0063465	Ligand	99.64%	Unkown
HY-156023	SIRT1 activator 2	Activator	99.28%	Unkown
HY-168336	E0924G	Activator	99.17%	Unkown
HY-169204	Mito-fisetin mF3	Inhibitor	/	Unkown
HY-172285	Cy3 hydrazide		/	Unkown
HY-172285A	Cy3 hydrazide bromide		98.89%	Unkown
HY-178239	DX-8951 Hydroxy-acid		/	Unkown
HY-I0626S1	Cytosine-13C,15N2		98%	Unkown
HY-N12486A	(3S,8R,9R)-Isofalcarintriol		/	Unkown
HY-N8375	Sieboldin	Inhibitor	98.80%	Unkown
HY-N9347	Stepharine	Inhibitor	98.0%	Unkown
HY-P5237	Tetrapeptide-4	Activator	99.54%	Unkown
HY-P5250	Palmitoyl tripeptide-5	Inhibitor	/	Unkown
HY-Q49697	Sirtuin modulator 3	Modulator	99.32%	Unkown
HY-W614656	Pterostilbene glucoside		99.80%	Unkown
HY-116711	11-cis-Retinal		65.0%	Unkown
HY-12688	Succinyl phosphonate	Inhibitor	/	Unkown
HY-181604	MDH2-IN-2	Inhibitor	/	Unkown
HY-19878	Seletinoid G	Agonist	90.86%	Unkown
HY-N1190	DL-Syringaresinol	Inhibitor	96%	Unkown
HY-N2026A	Propylparaben sodium		99.03%	Unkown
HY-N2026R	Propylparaben (Standard)		99.81%	Unkown
HY-RS17216	Ager Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W268155	3,4'-Dihydroxypropiophenone		95.35%	Unkown
HY-184142	EYE1118	Inhibitor	/	Unkown
HY-N6818R	5,7,4'-Trimethoxyflavone (Standard)		/	Unkown
HY-135435	SU10944	Inhibitor	/	Unkown
HY-10104	GRL-8234	Inhibitor	/	Unkown
HY-107317	7-Keto-Naturalean		/	Unkown
HY-107811A	Harmol hydrochloride		/	Unkown
HY-107965	Safflower oil (from Carthamus tinctorius seed)	Inhibitor	/	Unkown
HY-113033A	Pentosidine TFA		/	Unkown
HY-119125	BMS-317180	Agonist	/	Unkown
HY-123681	R 57720		/	Unkown
HY-124223	AF-DX 384 methanesulfonate	Antagonist	/	Unkown
HY-128135	MHY 553	Agonist	/	Unkown
HY-128387S	2,3-Butanediol-d6		/	Unkown
HY-128463S	N-tert-Butyl-α-phenylnitrone-d14		/	Unkown
HY-131528	Tenilsetam		99.79%	Unkown
HY-133804	Arteanoflavone	Inhibitor	/	Unkown
HY-133806	Fumarranol	Inhibitor	/	Unkown
HY-133968S1	24-Methylenecholesterol-13C		/	Unkown
HY-138830A	(S,S)-TAK-418	Inhibitor	/	Unkown
HY-142778	Lp-PLA2-IN-10		/	Unkown
HY-145545	1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE		/	Unkown
HY-14567A	Ciproxifan hydrochloride	Antagonist	/	Unkown
HY-148322	Sirtuin modulator 5	Modulator	/	Unkown
HY-14892C	Gemigliptin hydrochloride	Inhibitor	/	Unkown
HY-151487	CypD-IN-3	Inhibitor	/	Unkown
HY-151488	CypD-IN-4	Inhibitor	/	Unkown
HY-151489	CypE-IN-1	Inhibitor	/	Unkown
HY-151546	MRS4596	Antagonist	/	Unkown
HY-151547	MRS4719	Antagonist	/	Unkown
HY-153183	Lp-PLA2-IN-12	Inhibitor	/	Unkown
HY-153560	Lp-PLA2-IN-14	Inhibitor	/	Unkown
HY-15492A	AG-13958 (mono(hydrochloride))	Inhibitor	/	Unkown
HY-155138	GLS1 Inhibitor-7	Inhibitor	/	Unkown
HY-156434	PDE11A4-IN-1	Inhibitor	/	Unkown
HY-159925	QKY-613	Activator	98.24%	Unkown
HY-162269	Nampt activator-5	Activator	/	Unkown
HY-162515	8-OAc		/	Unkown
HY-162968	MRTF-A-IN-1	Inhibitor	/	Unkown
HY-162969	MRTF-A-IN-2	Inhibitor	/	Unkown
HY-163403	VEGFR-2-IN-43	Inhibitor	/	Unkown
HY-16561G	Resveratrol (GMP)		/	Unkown
HY-16561S1	Resveratrol-13C6		/	Unkown
HY-167711	Sirtuin modulator 9	Inducer	/	Unkown
HY-167740	Glycerophosphoinositol (lysine)		/	Unkown
HY-169846	CL5D		/	Unkown
HY-171336	TRC4186	Inhibitor	/	Unkown
HY-171925	BI-1124	Inhibitor	/	Unkown
HY-173337	HSP90α-IN-1	Inhibitor	/	Unkown
HY-174157	AR493	Activator	/	Unkown
HY-176127	JX10	Inhibitor	/	Unkown
HY-177945	MS99-β-Gal	Degrader	/	Unkown
HY-178284	Factor B-IN-7	Inhibitor	/	Unkown
HY-179657	PROTAC p300 degrader-2	Inhibitor	/	Unkown
HY-181589	PDE11A4-IN-2	Inhibitor	/	Unkown
HY-182303	Carboxyatractyloside	Inhibitor	/	Unkown
HY-182385	BPN-14136	Inhibitor	/	Unkown
HY-183057	GRK2 modulator 1		/	Unkown
HY-183306	mTOR/STAT3-IN-1	Inhibitor	/	Unkown
HY-183572	BW813U	Inhibitor	/	Unkown
HY-184141	EYE1090	Inhibitor	/	Unkown
HY-184158	HATC	Degrader	/	Unkown
HY-18740	Trequinsin	Inhibitor	/	Unkown
HY-B0801AS	Fexofenadine-d10 hydrochloride	Inhibitor	/	Unkown
HY-B1340S	Carbadox-d3	Inhibitor	/	Unkown
HY-D2990	KSA01		/	Unkown
HY-D2992	KSA02		/	Unkown
HY-D3208	oLOX		/	Unkown
HY-E70022	D-Mannose isomerase (PsMaSeAF)		/	Unkown
HY-E70410	NAD Synthetase		/	Unkown
HY-I0626S	Cytosine-13C2,15N3		/	Unkown
HY-N0679S	Retinyl acetate-d3		/	Unkown
HY-N0757R	8-O-Acetylharpagide (Standard)		/	Unkown
HY-N0859R	Schisanhenol (Standard)	Inhibitor	/	Unkown
HY-N1097	Venoterpine		/	Unkown
HY-N12653	Exserohilone	Inhibitor	/	Unkown
HY-N13232	Grape Skin Extract		/	Unkown
HY-N13380	6′‐O‐Galloylsalidroside		/	Unkown
HY-N15152	Isoaesculioside D		/	Unkown
HY-N1517A	(Rac)-Ganoderic acid C2	Inhibitor	/	Unkown
HY-N15225	12β-Hydroxyganoderenic acid B		/	Unkown
HY-N17816	Tambulin		/	Unkown
HY-N17872	Tenuifoliose W		/	Unkown
HY-N18386	Altissimacoumarin F		/	Unkown
HY-N18644	Calendula extract		/	Unkown
HY-N18682	Lonicera caprifolium extract		/	Unkown
HY-N18701	Achillea millefolium extract		/	Unkown
HY-N19082	Triphala extract		/	Unkown
HY-N19836	iso-Pedilanthocoumarin B		/	Unkown
HY-N2026AR	Propylparaben sodium (Standard)		/	Unkown
HY-N2026S	Propylparaben-d7		/	Unkown
HY-N20622	Terrestric acid		/	Unkown
HY-N2217R	Rotundic acid (Standard)		/	Unkown
HY-N2550	(+)-Coclaurine		/	Unkown
HY-N3612	Communic acid	Inhibitor	/	Unkown
HY-N6883	6-Methoxytricin	Inhibitor	/	Unkown
HY-NP002I	Sheep Serum Albumin		/	Unkown
HY-P0033A	Argireline acetate	Inhibitor	/	Unkown
HY-P10140	JNK-IN-15, Cell-Permeable	Inhibitor	/	Unkown
HY-P10141	JNK-IN-15, Cell-Permeable, Negative Control	Inhibitor	/	Unkown
HY-P10611	[D-Ser14]-Humanin		/	Unkown
HY-P11164	PRKGGRRRRAWGRRRRRRRRRRRRRRAPRKRLTLA	Ligand	/	Unkown
HY-P11656	α-Neoendorphin (porcine)		/	Unkown
HY-P1614	ZEP-3	Inhibitor	/	Unkown
HY-P2830	Complement factor D		/	Unkown
HY-P4308	Z-Pro-Pro-aldehyde-dimethyl acetal	Inhibitor	/	Unkown
HY-P5233	Acetyltetrapeptide 11	Inhibitor	/	Unkown
HY-RS00444	AGER Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W001083S1	3-Hydroxyphenylacetic acid-d5		/	Unkown
HY-W001083S2	3-Hydroxyphenylacetic acid-d6		/	Unkown
HY-W002968	SAHH-IN-1	Inhibitor	/	Unkown
HY-W127725	Thymolphthalexon tetrasodium		/	Unkown
HY-W127738	6-O-Stearoyl-L-ascorbic acid		/	Unkown
HY-W392413	Glutathione monoethyl ester	Inhibitor	/	Unkown
HY-W997836A	4-Amino-3-hydroxyphenylalanine dihydrochloride		98.97%	Unkown
HY-10380	(R)-DRF053	Inhibitor	/	Unkown
HY-107758	Y-29794 oxalate	Inhibitor	/	Unkown
HY-113033	Pentosidine		/	Unkown
HY-123754	AGN-201904	Inhibitor	/	Unkown
HY-123904	UoS12258	Activator	99.86%	Unkown
HY-138576	IDO1-IN-26	Inhibitor	98.22%	Unkown
HY-142025	Daumone		/	Unkown
HY-150179	ALCAT1-IN-1	Inhibitor	/	Unkown
HY-150361	Mouse Tert mRNA		/	Unkown
HY-154951	Oct4 inducer-2	Inducer	/	Unkown
HY-163103	(S)-Isomyosmine		/	Unkown
HY-165339	Lysyl-phenylalanyl-lysine	Inhibitor	/	Unkown
HY-167632	meso-Zeaxanthin		93.09%	Unkown
HY-168957	RuDiOBn	Inhibitor	/	Unkown
HY-169085	LRAT-IN-1	Inhibitor	/	Unkown
HY-174438	PSEC13	Modulator	/	Unkown
HY-175349	Tyrosinase-IN-43	Inhibitor	/	Unkown
HY-175862	ALR2-IN-9		/	Unkown
HY-185128	PE(P-16:0/18:2(9Z,12Z))		/	Unkown
HY-B1953S	Thiacloprid-d4	Agonist	/	Unkown
HY-N0363AR	(+)-Columbianetin acetate (Standard)		/	Unkown
HY-N0363R	(+)-Columbianetin (Standard)		/	Unkown
HY-N12071	Lucidin-ω-Me ether		/	Unkown
HY-N12486	Isofalcarintriol		/	Unkown
HY-N13261	Brickellin		/	Unkown
HY-N13299	Glucoberteroin		/	Unkown
HY-N8380	(-)-Latifolin		/	Unkown
HY-P3164	Acetyl tetrapeptide-9		/	Unkown
HY-RS23668	Ager Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W001288S	Indole-4-carboxaldehyde-13C	Activator	/	Unkown
HY-W050154S	Kojic acid-13C6	Inhibitor	/	Unkown
HY-W722107	Timonacic-d4		/	Unkown
HY-W997836	4-Amino-3-hydroxyphenylalanine		/	Unkown
HY-Y0785S	Glyoxal-d2		/	Unkown
HY-P3252AS	Pegcetacoplan-13C3,15N TFA		/	Unkown

Inhibitory Antibodies (12)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P9951A	Ranibizumab (anti-VEGF)	Inhibitor	99.60%	Unkown
HY-P991488	BI-765423	Inhibitor	95.52%	Unkown
HY-P990859	Anti-CD44 Antibody (Hermes-1)		≥95.0%	Unkown
HY-P991886	ANX-M1 (Human IgG1)	Inhibitor	99.0%	Unkown
HY-P990328	Anti-AGER/RAGE Antibody (XT-M4)	Inhibitor	≥99.0%	Unkown
HY-P99402	Rinucumab	Inhibitor	99.9%	Unkown
HY-P99905	Efdamrofusp alfa		99.89%	Unkown
HY-P992151	Sphingomab	Inhibitor	97.91%	Unkown
HY-P992142	Vonaprument	Inhibitor	/	Unkown
HY-P991385	UBX2050	Inhibitor	/	Unkown
HY-P991534	PF-04382923	Inhibitor	/	Unkown
HY-P992465	SIWA318H		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	AGER	MGD	MGI:893592
Canis familiaris	AGER	VGNC	VGNC:37699
Rattus norvegicus	AGER	RGD	RGD:69258
Macaca mulatta	AGER	VGNC	VGNC:69743
Bos taurus	AGER	VGNC	VGNC:25724
Felis catus	AGER	VGNC	VGNC:59680
Others	AGER	NCBI