BCL2 - BCL2, apoptosis regulator Gene

Also Known as Bcl-2

生物種: Rattus norvegicus

遺伝子タイプ: protein coding

遺伝子ID: 24224

About BCL2

Biased expression in Spleen (RPKM 83.4), Thymus (RPKM 72.9) and 9 other tissues.

Summary

Enables BH domain binding activity. Involved in several processes, including response to peptide; response to purine-containing compound; and response to vitamin. Located in cytosol; mitochondrial crista; and perinuclear region of cytoplasm. Used to study several diseases, including brain ischemia (multiple); end stage renal disease; gastric ulcer; intestinal disease (multiple); and status epilepticus. Biomarker of several diseases, including abdominal obesity-metabolic syndrome 1; brain disease (multiple); hypertension (multiple); intrinsic cardiomyopathy (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic Cancer (multiple); intracranial aneurysm; prostate cancer; and urinary bladder Cancer. Orthologous to human BCL2 (BCL2 Apoptosis regulator). [provided by Alliance of Genome Resources, Apr 2022]

BCL2 Products (1)

mRNA	Protein	Name
NM_016993.2	NP_058689.2	apoptosis regulator Bcl-2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	参考文献	由来
enables BH domain binding	IPI IPI: Inferred from physical interaction	9356461	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	15004018	RGD
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	9356461	RGD

Biological Process GO Annotation	Evidence	参考文献	由来
involved in cellular response to fluoride	IEP IEP: Inferred from expression pattern	16388103	RGD
involved in cellular response to glucose stimulus	IEP IEP: Inferred from expression pattern	21474815	RGD
involved in cellular response to hydrogen peroxide	IEP IEP: Inferred from expression pattern	16157298	RGD
involved in cellular response to hypoxia	IEP IEP: Inferred from expression pattern	20669351	RGD
involved in cellular response to organic cyclic compound	IEP IEP: Inferred from expression pattern	19574995	RGD
involved in cerebral cortex development	IEP IEP: Inferred from expression pattern	9813151	RGD
involved in glial cell apoptotic process	IEP IEP: Inferred from expression pattern	18931364	RGD
involved in liver regeneration	IEP IEP: Inferred from expression pattern	21503946	RGD
involved in negative regulation of apoptotic process	IDA IDA: Inferred from direct assay	11879647	RGD
involved in negative regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	15004018	RGD
involved in negative regulation of cardiac muscle cell apoptotic process	IMP IMP: Inferred from mutant phenotype	26692938	RGD
involved in oligodendrocyte differentiation	IEP IEP: Inferred from expression pattern	12787069	RGD
involved in ovarian follicle development	IEP IEP: Inferred from expression pattern	17570453	RGD
involved in response to L-ascorbic acid	IEP IEP: Inferred from expression pattern	18758938	RGD
involved in response to aluminum ion	IEP IEP: Inferred from expression pattern	17967740	RGD
involved in response to amyloid-beta	IEP IEP: Inferred from expression pattern	18374914	RGD
involved in response to cAMP	IEP IEP: Inferred from expression pattern	18086876	RGD
involved in response to caffeine	IEP IEP: Inferred from expression pattern	17236787	RGD
involved in response to copper ion	IEP IEP: Inferred from expression pattern	18289470	RGD
involved in response to corticosterone	IEP IEP: Inferred from expression pattern	17562391	RGD
involved in response to cytokine	IEP IEP: Inferred from expression pattern	18832793	RGD
involved in response to electrical stimulus	IEP IEP: Inferred from expression pattern	17700647	RGD
involved in response to erythropoietin	IEP IEP: Inferred from expression pattern	26261574	RGD
involved in response to estrogen	IEP IEP: Inferred from expression pattern	16084662	RGD
involved in response to ethanol	IDA IDA: Inferred from direct assay	18259862	RGD
involved in response to ethanol	IEP IEP: Inferred from expression pattern	15469889	RGD
involved in response to folic acid	IEP IEP: Inferred from expression pattern	18156304	RGD
involved in response to hypoxia	IEP IEP: Inferred from expression pattern	16445580	RGD
involved in response to insulin	IEP IEP: Inferred from expression pattern	18758938	RGD
involved in response to ischemia	IEP IEP: Inferred from expression pattern	31583047	RGD
involved in response to monosaccharide	IEP IEP: Inferred from expression pattern	26261574	RGD
involved in response to nicotine	IEP IEP: Inferred from expression pattern	15332118	RGD
involved in response to nutrient	IEP IEP: Inferred from expression pattern	16216918	RGD
involved in response to organic cyclic compound	IEP IEP: Inferred from expression pattern	18384965	RGD
involved in response to peptide hormone	IEP IEP: Inferred from expression pattern	15686664	RGD
involved in response to phenylpropanoid	IEP IEP: Inferred from expression pattern	22700048	RGD
involved in response to vitamin E	IEP IEP: Inferred from expression pattern	26261574	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	18284815	RGD

Cellular Component GO Annotation	Evidence	参考文献	由来
located in mitochondrial crista	IDA IDA: Inferred from direct assay	9731187	RGD
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	11299004	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BCL2 Protein Structure

bcl-2

0
100
200
236 a.a.

Protein Preferred Names	Protein Names
apoptosis regulator Bcl-2	B cell lymphoma 2 associated oncogene B-cell CLL/lymphoma 2 B-cell leukemia/lymphoma 2 Bcl-2alpha Bcl2-like protein

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (22)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-15531	Venetoclax		99.95%	Yes
HY-10201	Sorafenib		99.85%	Yes
HY-B0011	Docetaxel		99.94%	Unkown
HY-B0318	Metronidazole		99.98%	Yes
HY-10201A	Sorafenib tosylate		99.98%	Yes
HY-148026	Sonrotoclax	Inhibitor	99.61%	Unkown
HY-13407	Gossypol	Antagonist	99.67%	Yes
HY-10201S	Sorafenib-d3		99.57%	Unkown
HY-B0011A	Docetaxel Trihydrate		99.92%	Unkown
HY-17510	Gossypol (acetic acid)	Inhibitor	99.75%	Yes
HY-B0766	Bicyclol		99.91%	Unkown
HY-B1060	Methylprednisolone succinate sodium	Agonist	98.82%	Yes
HY-B1065	Aceglutamide		98.0%	Unkown
HY-15531R	Venetoclax (Standard)		99.90%	Unkown
HY-10201R	Sorafenib (Standard)		99.71%	Unkown
HY-W040128	Kanamycins sulfate		99.22%	Unkown
HY-B1900	Methylprednisolone succinate		99.67%	Yes
HY-B0011R	Docetaxel (Standard)		99.92%	Unkown
HY-B0877	Halcinonide		98.29%	Unkown
HY-B0420A	Moroxydine hydrochloride	Inhibitor	99.36%	Unkown
HY-B0318A	Metronidazole hydrochloride		98.44%	Yes
HY-10201AR	Sorafenib tosylate (Standard)		/	Unkown

Clinical Phase

Bioactive Molecules (34)

製品番号	製品名	製品効果	純度	Phase
HY-105930	Lobaplatin		98.0%	Phase 4
HY-10201S4	Sorafenib-d3 tosylate		/	Phase 4
HY-N14116	Garlic oil		/	Phase 4
HY-10087	Navitoclax	Inhibitor	99.97%	Phase 3
HY-N1423	Glycocholic acid		99.90%	Phase 3
HY-15464A	(R)-(-)-Gossypol acetic acid		98.93%	Phase 3
HY-10969A	Obatoclax		≥99.0%	Phase 3
HY-177102	Mesutoclax	Inhibitor	98.69%	Phase 3
HY-N0867	13-Oxyingenol-13-dodecanoate		99.37%	Phase 3
HY-118874	Oblimersen		/	Phase 3
HY-130604	DT2216		99.97%	Phase 2
HY-50868	Bafetinib		99.18%	Phase 2
HY-147081	AS 1411	Inhibitor	99.52%	Phase 2
HY-126741	Azadirachtin		99.06%	Phase 2
HY-109185	Pelcitoclax		99.70%	Phase 2
HY-N0068	Solasodine		99.97%	Phase 2
HY-15464	(R)-(-)-Gossypol		99.37%	Phase 2
HY-15464D	(S)-Gossypol (acetic acid)	Inhibitor	98.46%	Phase 2
HY-138697A	S65487 sulfate		99.35%	Phase 2
HY-175342	FCN-338	Inhibitor	99.33%	Phase 2
HY-N6674	Diazepinomicin		98.04%	Phase 2
HY-153495	Prexigebersen		/	Phase 2
HY-168739	Topoisomerase I inhibitor 17		/	Phase 2
HY-177618	Beclanorsen	Inhibitor	/	Phase 2
HY-177618A	Beclanorsen sodium	Inhibitor	/	Phase 2
HY-N0168	Hesperetin	Modulator	99.12%	Phase 1
HY-W250122	Glutamic acid sodium salt		99.92%	Phase 1
HY-155163	APG-2449	Inhibitor	98.93%	Phase 1
HY-109184	Murizatoclax	Inhibitor	98.84%	Phase 1
HY-117288A	S55746 hydrochloride	Inhibitor	98.83%	Phase 1
HY-156620	Lacutoclax	Inhibitor	/	Phase 1
HY-141876	PRT543		/	Phase 1
HY-168983	Lonitoclax	Inhibitor	/	Phase 1
HY-165550	Sphingosine		/	Phase 1

阻害性抗体 (1)

製品番号	製品名	製品効果	純度	Phase
HY-P991883	Metuzumab		/	Phase 4

Pre-clinical Phase

Bioactive Molecules (503)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-50907	ABT-737		99.64%	Unkown
HY-N0171A	Beta-Sitosterol (purity>98%)		99.74%	Unkown
HY-N0292	Oleuropein		99.97%	Unkown
HY-107738	Guggulsterone		99.83%	Unkown
HY-N0171	Beta-Sitosterol (purity>80%)	Inducer	≥98.0%	Unkown
HY-N2342	Procyanidin C1	Inducer	99.54%	Unkown
HY-N0087	Gambogic Acid		98.34%	Unkown
HY-10969	Obatoclax Mesylate		99.85%	Yes
HY-W250111	Carboxymethyl chitosan		90%	Unkown
HY-126477	NNK		99.97%	Unkown
HY-N0361	Dihydrocapsaicin		99.93%	Unkown
HY-N0674	Dehydrocorydaline		99.77%	Unkown
HY-18628	UMI-77	Inhibitor	99.66%	Unkown
HY-112416	AZD4320	Inhibitor	99.66%	Unkown
HY-103243	TCPOBOP	Inhibitor	99.70%	Unkown
HY-129179	Lisaftoclax		99.78%	Unkown
HY-147081A	AS 1411 sodium	Inhibitor	99.52%	Unkown
HY-174228	I3IN-002		99.35%	Unkown
HY-N0763	Angelicin		99.98%	Unkown
HY-N2897	Dihydrokaempferol		99.92%	Unkown
HY-155956	GM-90257		99.90%	Unkown
HY-N3584	Paris saponin VII		99.84%	Unkown
HY-128483	Fusaric acid		99.94%	Unkown
HY-15531S	Venetoclax-d8		99.76%	Unkown
HY-113438	15(S)-HPETE		97.32%	Unkown
HY-N0171R	Beta-Sitosterol (Standard)	Inducer	98.18%	Unkown
HY-124284	Hexamethylene bisacetamide		99.56%	Unkown
HY-N1255	Scoulerine		99.99%	Unkown
HY-138832	BM-1244		99.83%	Unkown
HY-N0559	Kirenol		99.82%	Unkown
HY-N1423A	Glycocholic acid sodium		99.24%	Unkown
HY-N1423S	Glycocholic acid-d4		99.92%	Unkown
HY-159059	Ganoderma lucidum polysaccharide		41.20%	Unkown
HY-N12060	Ginkgo biloba extract	Inhibitor	/	Unkown
HY-117288	S55746	Inhibitor	99.91%	Unkown
HY-12875	BQU57	Inhibitor	98.47%	Unkown
HY-N0657	Pinoresinol Diglucoside		99.84%	Unkown
HY-W017982	CMIT/MIT (14.5% in water)		97.0%	Unkown
HY-125876	PROTAC Bcl2 degrader-1	Inhibitor	99.80%	Unkown
HY-N1440	Koumine	Activator	99.97%	Unkown
HY-126437	Poly-L-lysine hydrobromide (MW 30000-70000)		/	Unkown
HY-N0674A	Dehydrocorydaline chloride		99.75%	Unkown
HY-125877	PROTAC Mcl1 degrader-1	Inhibitor	98.13%	Unkown
HY-B1839	Fluazinam		99.51%	Unkown
HY-N7675	Flavanomarein	Inhibitor	99.92%	Unkown
HY-P1527	Bim BH3		99.74%	Unkown
HY-78036	Mesaconic acid	Inhibitor	99.95%	Unkown
HY-101259	BMS-195614		99.5%	Unkown
HY-W017370	Carveol		98.32%	Unkown
HY-Y0315	Hexane-2,5-dione		99.96%	Unkown
HY-12020	TW-37	Inhibitor	99.50%	Unkown
HY-N6850	Calenduloside E		98.92%	Unkown
HY-33350	Clofilium tosylate		99.60%	Unkown
HY-P2970	Stem bromelain		/	Unkown
HY-N0392	Polygalasaponin F		99.85%	Unkown
HY-P1889	Bim BH3, Peptide IV		99.24%	Unkown
HY-153803	GBD-9	Degrader	99.91%	Unkown
HY-N2067	Vanillyl alcohol	Inhibitor	99.68%	Unkown
HY-N6005	Methyl caffeate		99.89%	Unkown
HY-15191	Sabutoclax	Inhibitor	99.80%	Unkown
HY-N2132	Flavokawain B		99.99%	Unkown
HY-P1380A	Difopein TFA		95.35%	Unkown
HY-N0863	Methyl protodioscin		99.67%	Unkown
HY-N3009	Secoxyloganin		99.33%	Unkown
HY-N6082	Rhein 8-O-β-D-Glucopyranoside	Inhibitor	99.81%	Unkown
HY-100383	BH3I-1		98.0%	Unkown
HY-125236	ZEN-3694		99.85%	Unkown
HY-101310	SYM 2081		98.0%	Unkown
HY-11095	NPS 2390		99.90%	Unkown
HY-126421	Kansuinine A		99.81%	Unkown
HY-129700	MCL-1/BCL-2-IN-2	Inhibitor	99.05%	Unkown
HY-N0566	23-Hydroxybetulinic acid		99.44%	Unkown
HY-N3031	Grosvenorine		99.64%	Unkown
HY-N3405	Lariciresinol		99.46%	Unkown
HY-133557	XZ739		99.08%	Unkown
HY-12011	HA14-1	Inhibitor	98.0%	Unkown
HY-157176	BAX-IN-1	Inhibitor	98.05%	Unkown
HY-169266	BRD-K56819078	Inhibitor	99.93%	Unkown
HY-50723	3-Methylxanthine		99.45%	Unkown
HY-N0757	8-O-Acetylharpagide		99.75%	Unkown
HY-N1983	Caudatin	Inducer	99.95%	Unkown
HY-139309	PROTAC Bcl-xL degrader-2	Inhibitor	98.23%	Unkown
HY-120882	BM-1197	Inhibitor	99.85%	Unkown
HY-101195	DL-erythro-Dihydrosphingosine	Inhibitor	98.0%	Unkown
HY-101997	BEPP hydrochloride		99.62%	Unkown
HY-107835	Flumethrin		99.29%	Unkown
HY-113471A	(S)-(-)-Perillic acid		99.9%	Unkown
HY-172209	PPIA-IN-1		96.90%	Unkown
HY-N0307	Ciwujianoside B	Inhibitor	99.68%	Unkown
HY-N0674B	Dehydrocorydaline (hydroxyl)		99.52%	Unkown
HY-W013105	Sodium glycocholate hydrate, 98%		99.91%	Unkown
HY-129681	MCL-1/BCL-2-IN-1	Inhibitor	98.65%	Unkown
HY-162858	BRD-810		98.00%	Unkown
HY-B0011S	Docetaxel-d9		98.65%	Unkown
HY-118874A	Oblimersen sodium	Inhibitor	98.09%	Unkown
HY-156278	FB49	Inhibitor	99.76%	Unkown
HY-16014	A-385358	Inhibitor	95.10%	Unkown
HY-161410	WH244	Degrader	99.82%	Unkown
HY-N2135	Puerarin 6''-O-Xyloside		99.81%	Unkown
HY-N2416	Taccalonolide A		99.29%	Unkown
HY-N5008	Macranthoside B		99.95%	Unkown
HY-N7930	Crenulatin		99.85%	Unkown
HY-NP192	Sericin		0%	Unkown
HY-119931	2-Hydroxychalcone		98.54%	Unkown
HY-172798	XZ338	Degrader	98.17%	Unkown
HY-179528	DIM-3,5-Cl2		99.18%	Unkown
HY-50723R	3-Methylxanthine (Standard)		99.58%	Unkown
HY-N6576	Hellebrigenin		99.69%	Unkown
HY-P2343	BH3 hydrochloride	Activator	98.03%	Unkown
HY-W007648	Methyl 3-aminopropanoate hydrochloride		≥98.0%	Unkown
HY-W674241	4-Ethylphenyl sulfate	Inducer	/	Unkown
HY-N0853A	Alisol A 24-acetate		98.0%	Unkown
HY-P10336	Serpinin	Agonist	98.74%	Unkown
HY-142209	ABBV-167	Inhibitor	98.10%	Unkown
HY-132307	Mcl-1 inhibitor 6		98.77%	Unkown
HY-16967	MM41		98.89%	Unkown
HY-101083	BDA-366	Antagonist	98.42%	Unkown
HY-147929	Apoptotic agent-3		98.19%	Unkown
HY-169265	BRD-K20733377	Inhibitor	99.50%	Unkown
HY-N6812	Karacoline		99.58%	Unkown
HY-167881	MLS-0053105	Inhibitor	98.89%	Unkown
HY-138697	S65487		99.91%	Unkown
HY-10087S	Navitoclax-d8		99.71%	Unkown
HY-10201S2	Sorafenib-13C,d3		98.35%	Unkown
HY-111329	JGB1741		99.37%	Unkown
HY-129702	MCL-1/BCL-2-IN-4	Inhibitor	99.95%	Unkown
HY-147785	Pim-1 kinase inhibitor 2		99.91%	Unkown
HY-156096	HDAC3-IN-2		/	Unkown
HY-158208	PMMB276	Inhibitor	99.81%	Unkown
HY-161100	BDM19	Inducer	99.38%	Unkown
HY-B1752	Quinpirole		98.95%	Unkown
HY-N0320	Salvianolic acid D		95.15%	Unkown
HY-N1157	Thevetiaflavone		99.83%	Unkown
HY-N1423B	Glycocholic acid hydrate		99.85%	Unkown
HY-N7653	Azaleatin		98.86%	Unkown
HY-N7905	Myricetin 3'-glucoside	Inhibitor	99.98%	Unkown
HY-N0882	Desacetylcinobufotalin		99.41%	Unkown
HY-N1414A	3′,6-Disinapoylsucrose	Inhibitor	98.88%	Unkown
HY-N1930	(-)-Hinesol	Inducer	98.7%	Unkown
HY-Y0315S	2,5-Hexanedione-d10		99.43%	Unkown
HY-111837	BI1071		98.93%	Unkown
HY-119979	Cardanol monoene	Inducer	99.51%	Unkown
HY-135273	A-1211212		98.43%	Unkown
HY-161254	ATPase-IN-3		99.89%	Unkown
HY-169925	BM-962	Inhibitor	99.10%	Unkown
HY-170820	XYD049	Inhibitor	99.46%	Unkown
HY-B1900R	Methylprednisolone succinate (Standard)		98.90%	Unkown
HY-N4238	Dehydrocorydaline nitrate		99.89%	Unkown
HY-109617	4-(4-Fluorophenyl)benzoic acid		99.01%	Unkown
HY-N13250	Hawthorn Extract		/	Unkown
HY-N4308	Hexamethylquercetagetin	Inhibitor	98.0%	Unkown
HY-RS01415	BCL2 Human Pre-designed siRNA Set A		/	Unkown
HY-W075770	Nickel(II) oxide		≥99.0%	Unkown
HY-10087A1	Navitoclax dihydrochloride		99.15%	Unkown
HY-138697B	S65487 hydrochloride		98.54%	Unkown
HY-19551	Apogossypolone		98.58%	Unkown
HY-119833	Rubone	Modulator	99.1%	Unkown
HY-129179B	(Rac)-Lisaftoclax	Inhibitor	98.22%	Unkown
HY-129488	FPFS-1169 hydrochloride	Agonist	99.83%	Unkown
HY-129701	MCL-1/BCL-2-IN-3	Inhibitor	98.93%	Unkown
HY-133772	Venetoclax N-oxide		99.66%	Unkown
HY-13408	(+)-Apogossypol	Inhibitor	/	Unkown
HY-160108	Bcl-2-IN-17	Inhibitor	/	Unkown
HY-160921	Capeserod	Agonist	98.66%	Unkown
HY-161276	BFC1108	Inducer	98.11%	Unkown
HY-161659	Apoptosis inducer 19		98.31%	Unkown
HY-174873	AF151		98.87%	Unkown
HY-N10144	Shinpterocarpin	Inhibitor	/	Unkown
HY-N1423S1	Glycocholic acid-d5		99.9%	Unkown
HY-N1983R	Caudatin (Standard)	Inducer	99.31%	Unkown
HY-N2199	Sotetsuflavone		96.75%	Unkown
HY-N6690	Destruxin B		99.86%	Unkown
HY-P1733	BMf-BH3		99.48%	Unkown
HY-P5325A	Bid BH3 (80-99) acetate		98.13%	Unkown
HY-RS01431	BCL2L13 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W017982A	CMIT/MIT (2.0-2.5% in water)		/	Unkown
HY-W073128	Perfluorotetradecanoic acid		98.0%	Unkown
HY-W674241A	4-Ethylphenyl sulfate sodium	Inducer	/	Unkown
HY-15191B	(S)-Sabutoclax	Inhibitor	98.03%	Unkown
HY-B1559	Allethrin	Inducer	98.04%	Unkown
HY-N1218	Stellasterol	Inhibitor	/	Unkown
HY-N16483	Procyanidin B2-3'-O-gallate		/	Unkown
HY-RS01421	BCL2L1 Human Pre-designed siRNA Set A		/	Unkown
HY-10201S1	Sorafenib-d4		99.9%	Unkown
HY-114310	VDR agonist 1		/	Unkown
HY-131247	Bcl-2-IN-2	Inhibitor	/	Unkown
HY-155188	NWP-0476	Inhibitor	/	Unkown
HY-100762	Mcl1-IN-11	Inhibitor	/	Unkown
HY-100763	Mcl1-IN-12	Inhibitor	/	Unkown
HY-146097	RMS5		/	Unkown
HY-149918	Antiproliferative agent-23		/	Unkown
HY-18106	BM 957	Inhibitor	/	Unkown
HY-184107	Bcl-2-IN-25	Inhibitor	/	Unkown
HY-78036R	Mesaconic acid (Standard)	Inhibitor	/	Unkown
HY-101999	EM20-25		/	Unkown
HY-107272	Chuanbeinone		/	Unkown
HY-107835R	Flumethrin (Standard)		/	Unkown
HY-107835S	Flumethrin-d5		/	Unkown
HY-115974	GRPR antagonist-1		99.80%	Unkown
HY-116204	SKLB70326		/	Unkown
HY-116267	MHY219		/	Unkown
HY-117171	Proquinazid		/	Unkown
HY-119062	A-800141	Inhibitor	/	Unkown
HY-121934	BH3I-2'		/	Unkown
HY-123020	CYD-2-88	Antagonist	98.52%	Unkown
HY-123034	CDKI-83		/	Unkown
HY-123244	YC137		/	Unkown
HY-123715	Anticancer agent 255		/	Unkown
HY-124122	BPTQ		/	Unkown
HY-124792	MRLB-223		/	Unkown
HY-125191	BRD1991	Inhibitor	/	Unkown
HY-126311	4-Hydroxyresveratrol	Inducer	/	Unkown
HY-127130	Spicamycin		/	Unkown
HY-131188	PROTAC Bcl-xL degrader-1	Inhibitor	/	Unkown
HY-131405	β-Eleostearic acid	Inhibitor	/	Unkown
HY-135275	BCL-XL-IN-4	Inhibitor	/	Unkown
HY-136778	INH2BP		/	Unkown
HY-13846	BM-1074		/	Unkown
HY-143235	BRD4 Inhibitor-15		/	Unkown
HY-143872	Bcl-2-IN-4	Inhibitor	/	Unkown
HY-143873	Bcl-2-IN-5	Inhibitor	/	Unkown
HY-144428	Bcl-2/Mcl-1-IN-2	Inhibitor	/	Unkown
HY-144430	Bcl-2/Mcl-1-IN-1	Inhibitor	/	Unkown
HY-144431	Bcl-2/Mcl-1-IN-3	Inhibitor	/	Unkown
HY-144778	IDO1/TDO-IN-1		/	Unkown
HY-144791	Bcl-2-IN-6		/	Unkown
HY-144792	Bcl-2-IN-7		/	Unkown
HY-145288	Antitumor agent-36		/	Unkown
HY-145289	Antitumor agent-37		/	Unkown
HY-146095	p53 Activator 2		/	Unkown
HY-146253	CDK1/2/4-IN-1		/	Unkown
HY-146444	Anticancer agent 56		/	Unkown
HY-146471	EGFR-IN-51		/	Unkown
HY-146472	EGFR-IN-52		/	Unkown
HY-146817	Tubulin polymerization-IN-11		/	Unkown
HY-147504	Anticancer agent 63		/	Unkown
HY-147826	EGFR-IN-60		/	Unkown
HY-147906	Anticancer agent 71		/	Unkown
HY-147928	Apoptotic agent-2		/	Unkown
HY-149009	Bcl-2-IN-9		/	Unkown
HY-149024	VEGFR-2-IN-23		/	Unkown
HY-149436	CDK2/Bcl2-IN-1	Inhibitor	/	Unkown
HY-149517	EGFR/BRAFV600E-IN-2		/	Unkown
HY-149622	Bcl-2-IN-12	Inhibitor	/	Unkown
HY-149623	Bcl-2-IN-13	Inhibitor	/	Unkown
HY-149624	Bcl-2-IN-14	Inhibitor	/	Unkown
HY-149625	Bcl-2-IN-15	Inhibitor	/	Unkown
HY-149681	Beclin1-Bcl-2 interaction inhibitor 1	Inhibitor	/	Unkown
HY-150540	Bcl-2-IN-10		/	Unkown
HY-150596	CT1-3		/	Unkown
HY-151428	Antitumor agent-78		/	Unkown
HY-151429	Antitumor agent-77		/	Unkown
HY-151443	HDAC-IN-47	Inhibitor	/	Unkown
HY-153494	Rosomidnar	Inhibitor	/	Unkown
HY-153494A	Rosomidnar sodium	Inhibitor	/	Unkown
HY-153953	Bcl-2-IN-11	Inhibitor	/	Unkown
HY-155242	VEGFR-2-IN-36		/	Unkown
HY-158551	PROTAC BcI-2/BcI-xI Degrader-1	Degrader	/	Unkown
HY-159513	Bcl-2/Mcl-1-IN-4	Inhibitor	/	Unkown
HY-159668	DL002		/	Unkown
HY-159817	Asaretoclax	Inhibitor	/	Unkown
HY-159938	p38α inhibitor 6		/	Unkown
HY-161415	BCL-xL/BCL-2 ligand 1		/	Unkown
HY-161577	BFC1103		/	Unkown
HY-161732	GQN-B37-E	Inhibitor	/	Unkown
HY-161786	Bcl-2-IN-20		/	Unkown
HY-162148	HNPMI	Inhibitor	99.57%	Unkown
HY-162820	Bcl-2-IN-21	Inhibitor	/	Unkown
HY-162826	Apoptosis inducer 27	Inducer	/	Unkown
HY-162886	BSO-07	Activator	/	Unkown
HY-163077	Anticancer agent 175	Inducer	/	Unkown
HY-163308	Bcl-2-IN-18	Inhibitor	/	Unkown
HY-163309	Bcl-2-IN-19	Inhibitor	/	Unkown
HY-163435	Anticancer agent 201		/	Unkown
HY-163527	FGFR-IN-13	Inhibitor	/	Unkown
HY-163764	Bfl-1-IN-4		/	Unkown
HY-167237	Calactin		/	Unkown
HY-168171	ERK1/2 inhibitor 11		/	Unkown
HY-168483	FTO-IN-13		/	Unkown
HY-168623	EGFR-IN-134		/	Unkown
HY-169083	Bcl-2-IN-22	Inhibitor	/	Unkown
HY-169096	DPP-21		/	Unkown
HY-169124	Apoptosis inducer 28		/	Unkown
HY-169267	BRD-K44839765	Inhibitor	/	Unkown
HY-169412	MAPK-IN-3		/	Unkown
HY-169431	VEGFR-2/AKT-IN-2		/	Unkown
HY-170366	VEGFR-2-IN-58		/	Unkown
HY-170648	TS-IN-5		/	Unkown
HY-170689	CG-3-246	Inhibitor	/	Unkown
HY-170787	TZEP7		/	Unkown
HY-170929	EMT inhibitor-3		/	Unkown
HY-170932	EGFR/COX-2-IN-1		/	Unkown
HY-170946	WR-S-462	Inhibitor	/	Unkown
HY-172092	BG11	Inducer	/	Unkown
HY-172393	TCF4/β-catenin-IN-1		/	Unkown
HY-172394	ZSNI-21		/	Unkown
HY-172551	anti-TNBC agent-9		/	Unkown
HY-172623	EGFR/HER2-IN-17		/	Unkown
HY-172886	PI3K-IN-58		/	Unkown
HY-173365	VEGFR-2-IN-67	Inhibitor	/	Unkown
HY-174232	EGFR/CA-IX-IN-1		/	Unkown
HY-174338	GPER/Bcl-2-IN-1	Inhibitor	/	Unkown
HY-174403	c-MYC/BCL2 ligand 1 iodide		/	Unkown
HY-174404	Topoisomerase II inhibitor 23		/	Unkown
HY-174419	TFSeB		/	Unkown
HY-174469	PROTAC PI3K/110β degrader-2		/	Unkown
HY-174855	PI3K/mTOR-IN-17		/	Unkown
HY-174992	Apoptosis inducer 39	Inducer	/	Unkown
HY-175010	STAT3-IN-44		/	Unkown
HY-175021	HDAC-IN-91		/	Unkown
HY-175034	Topoisomerase I/II-IN-1		/	Unkown
HY-175037	DNH28		/	Unkown
HY-175227	STAT3/NF-κB-IN-1		/	Unkown
HY-175317	Nogo-B-IN-1		/	Unkown
HY-175332	Apoptosis inducer 43		/	Unkown
HY-175397	Dth		/	Unkown
HY-175588	EGFR-IN-170		/	Unkown
HY-175638	Carbonic anhydrase-IN-35		/	Unkown
HY-175771	STAT3-IN-46	Inhibitor	/	Unkown
HY-175815	Apoptosis inducer 44		/	Unkown
HY-175841	Tau Protein Phosphorylation-IN-1	Inhibitor	/	Unkown
HY-175848	NSC 850745		/	Unkown
HY-176219	Bcl-2-IN-23		/	Unkown
HY-176279	Hsp90-IN-42		/	Unkown
HY-17662	Mol4	Inhibitor	/	Unkown
HY-177076	Dalvotoclax	Inhibitor	/	Unkown
HY-177208	BW-AQ-113		/	Unkown
HY-178008	Mcl-1-IN-16		/	Unkown
HY-178036	ZM484	Inhibitor	/	Unkown
HY-178099	Apoptosis inducer 45		/	Unkown
HY-178176	PROTAC CB1R Degrader-1		/	Unkown
HY-178351	HDAC6-IN-67		/	Unkown
HY-178373	Topoisomerase I-IN-18		/	Unkown
HY-178380	HDAC8-IN-14		/	Unkown
HY-178446	METTL3-IN-11	Inhibitor	/	Unkown
HY-178910	Mcl-1-IN-20		/	Unkown
HY-178911	TS-IN-8		/	Unkown
HY-178940	Apoptosis inducer 49		/	Unkown
HY-178942	EGFR/VEGFR2-IN-9		/	Unkown
HY-179125	COX-2-IN-59		/	Unkown
HY-179155	PI3K/mTOR-IN-19		/	Unkown
HY-179161	CDK2-IN-49		/	Unkown
HY-179439	Multi-kinase-IN-8		/	Unkown
HY-179480	G-quadruplex ligand 4		/	Unkown
HY-179485	EGFR/VEGFR2-IN-10		/	Unkown
HY-179520	XSJ151		/	Unkown
HY-179522	EGFR-IN-186		/	Unkown
HY-180154	EGFR/BRAFV600E-IN-6		/	Unkown
HY-180190	Tubulin polymerization-IN-85		/	Unkown
HY-180196	EGFR-IN-187		/	Unkown
HY-180242	EGFR/CDK2-IN-5		/	Unkown
HY-180245	STAT3-IN-51		/	Unkown
HY-180274	JAK1/2-IN-3		/	Unkown
HY-180324	Candidone		/	Unkown
HY-180618	p53 DUBTAC modulator-1		/	Unkown
HY-180820	Dimethyl bisphenolate		/	Unkown
HY-180823	Topoisomerase II/EGFR-IN-2		/	Unkown
HY-180848	Bcl-2-IN-24		/	Unkown
HY-181015	α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu		/	Unkown
HY-181018	Topo I/DDX5-IN-1		/	Unkown
HY-181060	Apoptosis inducer 56		/	Unkown
HY-181061	COX/5-LO-IN-2		/	Unkown
HY-181087	Anticancer agent 296		/	Unkown
HY-181174	Antioxidant agent-22		/	Unkown
HY-181413	PROTAC EZH2 Degrader-44		/	Unkown
HY-181477	ERK5-IN-7		/	Unkown
HY-181505	BRD4-IN-12		/	Unkown
HY-181673	ICD inducer-2		/	Unkown
HY-181723	Anticancer agent 304		/	Unkown
HY-181725	Topoisomerase I-IN-20		/	Unkown
HY-181746	Bcl-2/Mcl-1-IN-5		/	Unkown
HY-181769	Anticancer agent 306		/	Unkown
HY-181795	CSN5-IN-3		/	Unkown
HY-182060	PDE4B/D-IN-5		/	Unkown
HY-182069	CDK9-IN-47		/	Unkown
HY-182243	HK2-IN-4		99.85%	Unkown
HY-182284	Anticancer agent 310		/	Unkown
HY-182360	Cytisine-platinum(IV) prodrug-1		/	Unkown
HY-182469	FuBIG		/	Unkown
HY-182706	NSC 373981	Inhibitor	/	Unkown
HY-182745	VEGFR-2-IN-85		/	Unkown
HY-182759	MN33-47		/	Unkown
HY-182760	MN33-63		/	Unkown
HY-182986	LS-Q2		/	Unkown
HY-183069	FKL-137		/	Unkown
HY-183327	PI3K/mTOR-IN-22	Inhibitor	/	Unkown
HY-183330	Topo I/II-IN-3		/	Unkown
HY-183355	KRAS G12D-IN-37		/	Unkown
HY-183369	VEGFR/PD-L1-IN-1		/	Unkown
HY-183390	Scopadulciol		/	Unkown
HY-183791A	Ferroptosis/apoptosis inducer-5		/	Unkown
HY-184116	A2AR/EGFR-IN-1		/	Unkown
HY-184145	AKT1-IN-13		/	Unkown
HY-184274	EGFR/c-SRC-IN-1		/	Unkown
HY-184302	Apoptosis inducer 62		/	Unkown
HY-184386	Aurora kinase-IN-15		/	Unkown
HY-184443	Bcl-2-IN-26		/	Unkown
HY-184501	UE01		/	Unkown
HY-184737	TPP-C8-CO-DSG bromide		/	Unkown
HY-184891	W1307	Inhibitor	/	Unkown
HY-185559	Mito-fisetin mF7		/	Unkown
HY-186248	BCS12		99.94%	Unkown
HY-18628S	UMI-77-d4	Inhibitor	/	Unkown
HY-187115	GGW		/	Unkown
HY-187459	Topoisomerase I-IN-23		/	Unkown
HY-50907S	ABT-737-d8		99.11%	Unkown
HY-B0011AS	Docetaxel-d5 trihydrate		/	Unkown
HY-N0307R	Ciwujianoside B (Standard)	Inhibitor	/	Unkown
HY-N0361S	Dihydrocapsaicin-d3		/	Unkown
HY-N0392R	Polygalasaponin F (Standard)	Inhibitor	/	Unkown
HY-N0559R	Kirenol (Standard)		/	Unkown
HY-N0757R	8-O-Acetylharpagide (Standard)		/	Unkown
HY-N10091	2,3-Dihydro-3α-methoxynimbolide		/	Unkown
HY-N10342	Cajanol		/	Unkown
HY-N1255A	Scoulerine hydrochloride		/	Unkown
HY-N13338	Avicin D		/	Unkown
HY-N14116A	Garlic oil (synthetic)		/	Unkown
HY-N15449	Vicanicin		/	Unkown
HY-N16771	Clausenidin		/	Unkown
HY-N16929	Gymnoside II		/	Unkown
HY-N17440	2-Methoxyjuglone		/	Unkown
HY-N17617	S-Petasin		/	Unkown
HY-N17816	Tambulin		/	Unkown
HY-N19029	Vernodalin		/	Unkown
HY-N20627	Withametelin B		/	Unkown
HY-N2741	Vitexin B-1	Inhibitor	/	Unkown
HY-N3828	epi-Eriocalyxin A		/	Unkown
HY-N6799	Neosolaniol		99.72%	Unkown
HY-N7917	Tenacigenoside A		/	Unkown
HY-N9778	Phoyunbene B		/	Unkown
HY-P10057	cpm-1285	Inducer	/	Unkown
HY-P10058	cpm-1285m		/	Unkown
HY-P10614	Bid BH3 peptide	Inducer	/	Unkown
HY-P10614A	Bid BH3 peptide acetate	Inducer	98.13%	Unkown
HY-P10833	C-VGB3		/	Unkown
HY-P11374	Bid BH3-Gly-r8	Ligand	/	Unkown
HY-P11707	FS1 peptide		/	Unkown
HY-P11935	RR-171		/	Unkown
HY-P1380	Difopein		/	Unkown
HY-P1889A	Bim BH3, Peptide IV TFA		/	Unkown
HY-P5324	Bad BH3 (mouse)		/	Unkown
HY-P5325	Bid BH3 (80-99)		/	Unkown
HY-P5327	r8 Bid BH3		/	Unkown
HY-RS01416	Bcl2 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS01417	BCL2 Rat Pre-designed siRNA Set A		/	Unkown
HY-RS01418	BCL2A1 Human Pre-designed siRNA Set A		/	Unkown
HY-RS01419	Bcl2a1 Rat Pre-designed siRNA Set A		/	Unkown
HY-RS01420	Bcl2a1a Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS01422	Bcl2l1 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS01423	Bcl2l1 Rat Pre-designed siRNA Set A		/	Unkown
HY-RS01424	BCL2L10 Human Pre-designed siRNA Set A		/	Unkown
HY-RS01425	Bcl2l10 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS01426	Bcl2l10 Rat Pre-designed siRNA Set A		/	Unkown
HY-RS01427	BCL2L11 Human Pre-designed siRNA Set A		/	Unkown
HY-RS01428	Bcl2l11 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS01429	Bcl2l11 Rat Pre-designed siRNA Set A		/	Unkown
HY-RS01430	BCL2L12 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS01432	BCL2L14 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS01433	BCL2L15 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS01434	BCL2L2 Human Pre-designed siRNA Set A		/	Unkown
HY-RS01435	Bcl2l2 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS01436	Bcl2l2 Rat Pre-designed siRNA Set A		/	Unkown
HY-W016937	Moroxydine	Inhibitor	/	Unkown
HY-W017370R	Carveol (Standard)		/	Unkown
HY-W713297	Moroxydine hydrochloride-d8	Inhibitor	/	Unkown
HY-W717425	SC-60		/	Unkown
HY-W754548	Glycocholic acid-13C2,d4		/	Unkown
HY-101083A	(Rac)-BDA-366	Inhibitor	/	Unkown
HY-115529	(-)BI97D6	Inducer	/	Unkown
HY-116532	YCW-E11	Inhibitor	/	Unkown
HY-117136	AN-7		/	Unkown
HY-12011A	(Rac)-HA14-1	Inhibitor	/	Unkown
HY-122047	SW063058		/	Unkown
HY-136714	Bcl-2-IN-3	Inhibitor	/	Unkown
HY-15531S1	Venetoclax-d6		/	Unkown
HY-164468	Ch282-5	Inhibitor	/	Unkown
HY-167825	Barakol		/	Unkown
HY-171031	TFGF-18		/	Unkown
HY-174635	Human IL15RA mRNA		/	Unkown
HY-174776	Human BAX mRNA		/	Unkown
HY-174777	Human BAK1 mRNA		/	Unkown
HY-181030	BDE30671203		/	Unkown
HY-182586	Decyl gallate	Activator	/	Unkown
HY-183402	FLLL12		/	Unkown
HY-184378	MDB5		/	Unkown
HY-184835	Uranyl acetate		/	Unkown
HY-50723S1	3-Methylxanthine-d3		/	Unkown
HY-N11231	Fucoxanthinol		/	Unkown
HY-N15136	Isomorellinol	Inducer	/	Unkown
HY-N15315	Triptriolide		/	Unkown
HY-N15378	β-Carotene-15,15'-epoxide		/	Unkown
HY-N15466	Longan cerebroside II	Inhibitor	/	Unkown
HY-N18905	α-D-Glucosyl hesperidin		/	Unkown
HY-N19904	Rhodomyrtosone D	Inhibitor	/	Unkown
HY-N6082R	Rhein 8-O-β-D-Glucopyranoside (Standard)		/	Unkown
HY-N6799R	Neosolaniol (Standard)		/	Unkown
HY-N6926	1,3,5-Tricaffeoylquinic acid		/	Unkown
HY-N8579	Eugenyl benzoate		≥90.0%	Unkown
HY-RS21989	Bcl2l12 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28507	Bcl2l12 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W715812	Bromuconazole		/	Unkown
HY-W747601	Chlorphoxim		/	Unkown
HY-W751400	Solasodine hydrochloride		/	Unkown

阻害性抗体 (1)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-P990344	Anti-Bcl-2 Antibody	Inhibitor	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Homo sapiens	BCL2	NCBI	NCBI:596