Bcl2 - B cell leukemia/lymphoma 2 Gene
Also Known as Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik
Species: Mus musculus
Gene Type: protein coding
Gene ID: 12043
About Bcl2
Chromosome 1: 106,465,908-106,642,004 reverse strand.GRCm39:CM000994.3
This gene has 2 transcripts (splice variants), 230 orthologues, 10 paralogues and is associated with 133 phenotypes. Ubiquitous expression in spleen adult (RPKM 4.5), limb E14.5 (RPKM 2.8) and 23 other tissues.
Summary
This gene encodes a member of the B cell lymphoma 2 protein family. Members of this family regulate cell death in multiple cell types and can have either proapoptotic or antiapoptotic activities. The protein encoded by this gene inhibits mitochondrial-mediated Apoptosis. This protein is an integral outer mitochondrial membrane protein that functions as part of signaling pathway that controls mitochondrial permeability in response to apoptotic stimuli. This protein may also play a role in neuron cell survival and Autophagy. Abnormal expression and chromosomal translocations of this gene are associated with Cancer progression in numerous tissues. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Bcl2 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_177410.3 | NP_803129.2 | apoptosis regulator Bcl-2 isoform 2 |
| NM_009741.5 | NP_033871.2 | apoptosis regulator Bcl-2 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables molecular adaptor activity |
IDA
IDA: Inferred from direct assay
|
36812915 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
7834748 | MGI |
| enables protein phosphatase 2A binding |
IDA
IDA: Inferred from direct assay
|
16717086 | MGI |
| enables protein phosphatase binding |
IDA
IDA: Inferred from direct assay
|
12617961 | MGI |
| enables transcription factor binding |
IPI
IPI: Inferred from physical interaction
|
17382917 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| is active in cytoplasm |
IDA
IDA: Inferred from direct assay
|
36812915 | MGI |
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
7563251 | MGI |
| located in cytosol |
IDA
IDA: Inferred from direct assay
|
8030757 | MGI |
| located in endoplasmic reticulum |
IDA
IDA: Inferred from direct assay
|
8030757 | MGI |
| located in endoplasmic reticulum membrane |
IDA
IDA: Inferred from direct assay
|
15613488 | MGI |
| located in intracellular anatomical structure |
IDA
IDA: Inferred from direct assay
|
9008714 | MGI |
| located in membrane |
IDA
IDA: Inferred from direct assay
|
8030757 | MGI |
| located in mitochondrial membrane |
IDA
IDA: Inferred from direct assay
|
11980919 | MGI |
| located in mitochondrion |
IDA
IDA: Inferred from direct assay
|
7945396 | MGI |
| located in myelin sheath |
IDA
IDA: Inferred from direct assay
|
7953633 | MGI |
| located in nuclear membrane |
IDA
IDA: Inferred from direct assay
|
8030757 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
7945396 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
Bcl2 Protein Structure
bcl-2
bcl-2: TIGR00865 (10 - 235)
- 0
- 100
- 200
- 236 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
apoptosis regulator Bcl-2 |
|
Recombinant Bcl2 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P72101 | BCL2 Protein, Mouse (His) | P10417-1 (G5-P205) | ≥ 90%, as determined by reducing SDS-PAGE. |
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(19)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-15531 | Venetoclax | 99.95% | Yes | |
| HY-10201 | Sorafenib | 99.85% | Yes | |
| HY-B0011 | Docetaxel | 99.94% | Unkown | |
| HY-B0318 | Metronidazole | 99.98% | Yes | |
| HY-10201A | Sorafenib tosylate | 99.98% | Yes | |
| HY-148026 | Sonrotoclax | Inhibitor | 99.61% | Unkown |
| HY-13407 | Gossypol | Antagonist | 99.67% | Yes |
| HY-B0011A | Docetaxel Trihydrate | 99.92% | Unkown | |
| HY-17510 | Gossypol (acetic acid) | Inhibitor | 99.75% | Yes |
| HY-B0766 | Bicyclol | 99.91% | Unkown | |
| HY-B1060 | Methylprednisolone succinate sodium | Agonist | 98.82% | Yes |
| HY-B1065 | Aceglutamide | 98.0% | Unkown | |
| HY-15531R | Venetoclax (Standard) | 99.90% | Unkown | |
| HY-W040128 | Kanamycins sulfate | 99.22% | Unkown | |
| HY-B1900 | Methylprednisolone succinate | 99.67% | Yes | |
| HY-B0011R | Docetaxel (Standard) | 99.92% | Unkown | |
| HY-B0877 | Halcinonide | 98.29% | Unkown | |
| HY-B0420A | Moroxydine hydrochloride | Inhibitor | 99.36% | Unkown |
| HY-B0318A | Metronidazole hydrochloride | 98.44% | Yes |
Clinical Phase
Bioactive Molecules
(33)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-105930 | Lobaplatin | 98.0% | Phase 4 | |
| HY-N14116 | Garlic oil | / | Phase 4 | |
| HY-10087 | Navitoclax | Inhibitor | 99.97% | Phase 3 |
| HY-N1423 | Glycocholic acid | 99.90% | Phase 3 | |
| HY-15464A | (R)-(-)-Gossypol acetic acid | 98.93% | Phase 3 | |
| HY-10969A | Obatoclax | ≥99.0% | Phase 3 | |
| HY-177102 | Mesutoclax | Inhibitor | 98.69% | Phase 3 |
| HY-N0867 | 13-Oxyingenol-13-dodecanoate | 99.37% | Phase 3 | |
| HY-118874 | Oblimersen | / | Phase 3 | |
| HY-130604 | DT2216 | 99.97% | Phase 2 | |
| HY-50868 | Bafetinib | 99.18% | Phase 2 | |
| HY-147081 | AS 1411 | Inhibitor | 99.52% | Phase 2 |
| HY-126741 | Azadirachtin | 99.06% | Phase 2 | |
| HY-109185 | Pelcitoclax | 99.70% | Phase 2 | |
| HY-N0068 | Solasodine | 99.97% | Phase 2 | |
| HY-15464 | (R)-(-)-Gossypol | 99.37% | Phase 2 | |
| HY-15464D | (S)-Gossypol (acetic acid) | Inhibitor | 98.46% | Phase 2 |
| HY-138697A | S65487 sulfate | 99.35% | Phase 2 | |
| HY-175342 | FCN-338 | Inhibitor | 99.33% | Phase 2 |
| HY-N6674 | Diazepinomicin | 98.04% | Phase 2 | |
| HY-153495 | Prexigebersen | / | Phase 2 | |
| HY-168739 | Topoisomerase I inhibitor 17 | / | Phase 2 | |
| HY-177618 | Beclanorsen | Inhibitor | / | Phase 2 |
| HY-177618A | Beclanorsen sodium | Inhibitor | / | Phase 2 |
| HY-N0168 | Hesperetin | Modulator | 99.12% | Phase 1 |
| HY-W250122 | Glutamic acid sodium salt | 99.92% | Phase 1 | |
| HY-155163 | APG-2449 | Inhibitor | 98.93% | Phase 1 |
| HY-109184 | Murizatoclax | Inhibitor | 98.84% | Phase 1 |
| HY-117288A | S55746 hydrochloride | Inhibitor | 98.83% | Phase 1 |
| HY-156620 | Lacutoclax | Inhibitor | / | Phase 1 |
| HY-141876 | PRT543 | / | Phase 1 | |
| HY-168983 | Lonitoclax | Inhibitor | / | Phase 1 |
| HY-165550 | Sphingosine | / | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(494)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-50907 | ABT-737 | 99.64% | Unkown | |
| HY-N0171A | Beta-Sitosterol (purity>98%) | 99.74% | Unkown | |
| HY-N0292 | Oleuropein | 99.97% | Unkown | |
| HY-107738 | Guggulsterone | 99.83% | Unkown | |
| HY-N0171 | Beta-Sitosterol (purity>80%) | Inducer | ≥98.0% | Unkown |
| HY-N2342 | Procyanidin C1 | Inducer | 99.54% | Unkown |
| HY-N0087 | Gambogic Acid | 98.34% | Unkown | |
| HY-10969 | Obatoclax Mesylate | 99.85% | Yes | |
| HY-W250111 | Carboxymethyl chitosan | 90% | Unkown | |
| HY-126477 | NNK | 99.97% | Unkown | |
| HY-N0361 | Dihydrocapsaicin | 99.93% | Unkown | |
| HY-N0674 | Dehydrocorydaline | 99.77% | Unkown | |
| HY-18628 | UMI-77 | Inhibitor | 99.66% | Unkown |
| HY-112416 | AZD4320 | Inhibitor | 99.66% | Unkown |
| HY-103243 | TCPOBOP | Inhibitor | 99.70% | Unkown |
| HY-129179 | Lisaftoclax | 99.78% | Unkown | |
| HY-147081A | AS 1411 sodium | Inhibitor | 99.52% | Unkown |
| HY-174228 | I3IN-002 | 99.35% | Unkown | |
| HY-N0763 | Angelicin | 99.98% | Unkown | |
| HY-N2897 | Dihydrokaempferol | 99.92% | Unkown | |
| HY-155956 | GM-90257 | 99.90% | Unkown | |
| HY-N3584 | Paris saponin VII | 99.84% | Unkown | |
| HY-128483 | Fusaric acid | 99.94% | Unkown | |
| HY-15531S | Venetoclax-d8 | 99.76% | Unkown | |
| HY-113438 | 15(S)-HPETE | 97.32% | Unkown | |
| HY-N0171R | Beta-Sitosterol (Standard) | Inducer | 98.18% | Unkown |
| HY-124284 | Hexamethylene bisacetamide | 99.56% | Unkown | |
| HY-N1255 | Scoulerine | 99.99% | Unkown | |
| HY-138832 | BM-1244 | 99.83% | Unkown | |
| HY-N0559 | Kirenol | 99.82% | Unkown | |
| HY-N1423A | Glycocholic acid sodium | 97.0% | Unkown | |
| HY-N1423S | Glycocholic acid-d4 | 99.92% | Unkown | |
| HY-159059 | Ganoderma lucidum polysaccharide | 41.20% | Unkown | |
| HY-N12060 | Ginkgo biloba extract | Inhibitor | / | Unkown |
| HY-117288 | S55746 | Inhibitor | 99.91% | Unkown |
| HY-12875 | BQU57 | Inhibitor | 98.47% | Unkown |
| HY-N0657 | Pinoresinol Diglucoside | 99.84% | Unkown | |
| HY-W017982 | CMIT/MIT (14.5% in water) | 97.0% | Unkown | |
| HY-125876 | PROTAC Bcl2 degrader-1 | Inhibitor | 99.80% | Unkown |
| HY-N1440 | Koumine | Activator | 99.97% | Unkown |
| HY-126437 | Poly-L-lysine hydrobromide (MW 30000-70000) | / | Unkown | |
| HY-N0674A | Dehydrocorydaline chloride | 99.75% | Unkown | |
| HY-125877 | PROTAC Mcl1 degrader-1 | Inhibitor | 98.13% | Unkown |
| HY-B1839 | Fluazinam | 99.51% | Unkown | |
| HY-N7675 | Flavanomarein | Inhibitor | 99.92% | Unkown |
| HY-P1527 | Bim BH3 | 99.74% | Unkown | |
| HY-78036 | Mesaconic acid | Inhibitor | 99.95% | Unkown |
| HY-101259 | BMS-195614 | 99.5% | Unkown | |
| HY-W017370 | Carveol | 98.32% | Unkown | |
| HY-Y0315 | Hexane-2,5-dione | 99.96% | Unkown | |
| HY-12020 | TW-37 | Inhibitor | 99.50% | Unkown |
| HY-N6850 | Calenduloside E | 99.07% | Unkown | |
| HY-33350 | Clofilium tosylate | 99.60% | Unkown | |
| HY-P2970 | Stem bromelain | / | Unkown | |
| HY-N0392 | Polygalasaponin F | 99.85% | Unkown | |
| HY-P1889 | Bim BH3, Peptide IV | 99.24% | Unkown | |
| HY-153803 | GBD-9 | Degrader | 99.91% | Unkown |
| HY-N2067 | Vanillyl alcohol | Inhibitor | 99.68% | Unkown |
| HY-N6005 | Methyl caffeate | 99.89% | Unkown | |
| HY-15191 | Sabutoclax | Inhibitor | 99.80% | Unkown |
| HY-N2132 | Flavokawain B | 99.99% | Unkown | |
| HY-P1380A | Difopein TFA | 95.35% | Unkown | |
| HY-N0863 | Methyl protodioscin | 99.67% | Unkown | |
| HY-N3009 | Secoxyloganin | 99.33% | Unkown | |
| HY-N6082 | Rhein 8-O-β-D-Glucopyranoside | Inhibitor | 99.81% | Unkown |
| HY-100383 | BH3I-1 | 98.0% | Unkown | |
| HY-125236 | ZEN-3694 | 99.85% | Unkown | |
| HY-101310 | SYM 2081 | 98.0% | Unkown | |
| HY-11095 | NPS 2390 | 99.90% | Unkown | |
| HY-126421 | Kansuinine A | 99.81% | Unkown | |
| HY-129700 | MCL-1/BCL-2-IN-2 | Inhibitor | 99.05% | Unkown |
| HY-N0566 | 23-Hydroxybetulinic acid | 99.44% | Unkown | |
| HY-N3031 | Grosvenorine | 99.64% | Unkown | |
| HY-N3405 | Lariciresinol | 99.46% | Unkown | |
| HY-133557 | XZ739 | 99.08% | Unkown | |
| HY-12011 | HA14-1 | Inhibitor | 98.0% | Unkown |
| HY-157176 | BAX-IN-1 | Inhibitor | 98.05% | Unkown |
| HY-169266 | BRD-K56819078 | Inhibitor | 99.93% | Unkown |
| HY-N0757 | 8-O-Acetylharpagide | 99.75% | Unkown | |
| HY-N1983 | Caudatin | Inducer | 99.95% | Unkown |
| HY-139309 | PROTAC Bcl-xL degrader-2 | Inhibitor | 98.23% | Unkown |
| HY-120882 | BM-1197 | Inhibitor | 99.48% | Unkown |
| HY-101195 | DL-erythro-Dihydrosphingosine | Inhibitor | 98.0% | Unkown |
| HY-101997 | BEPP hydrochloride | 99.62% | Unkown | |
| HY-107835 | Flumethrin | 99.29% | Unkown | |
| HY-113471A | (S)-(-)-Perillic acid | 99.9% | Unkown | |
| HY-172209 | PPIA-IN-1 | 96.90% | Unkown | |
| HY-N0307 | Ciwujianoside B | Inhibitor | 99.68% | Unkown |
| HY-N0674B | Dehydrocorydaline (hydroxyl) | 99.52% | Unkown | |
| HY-W013105 | Sodium glycocholate hydrate, 98% | 99.91% | Unkown | |
| HY-129681 | MCL-1/BCL-2-IN-1 | Inhibitor | 98.65% | Unkown |
| HY-162858 | BRD-810 | 98.00% | Unkown | |
| HY-B0011S | Docetaxel-d9 | 98.65% | Unkown | |
| HY-118874A | Oblimersen sodium | Inhibitor | 98.09% | Unkown |
| HY-156278 | FB49 | Inhibitor | 99.76% | Unkown |
| HY-16014 | A-385358 | Inhibitor | 95.10% | Unkown |
| HY-161410 | WH244 | Degrader | 99.82% | Unkown |
| HY-N2135 | Puerarin 6''-O-Xyloside | 99.81% | Unkown | |
| HY-N2416 | Taccalonolide A | 99.29% | Unkown | |
| HY-N5008 | Macranthoside B | 99.95% | Unkown | |
| HY-N7930 | Crenulatin | 99.85% | Unkown | |
| HY-NP192 | Sericin | 0% | Unkown | |
| HY-119931 | 2-Hydroxychalcone | 98.54% | Unkown | |
| HY-172798 | XZ338 | Degrader | 98.17% | Unkown |
| HY-179528 | DIM-3,5-Cl2 | 99.18% | Unkown | |
| HY-N6576 | Hellebrigenin | 99.69% | Unkown | |
| HY-P2343 | BH3 hydrochloride | Activator | 98.03% | Unkown |
| HY-W007648 | Methyl 3-aminopropanoate hydrochloride | ≥98.0% | Unkown | |
| HY-W674241 | 4-Ethylphenyl sulfate | Inducer | / | Unkown |
| HY-N0853A | Alisol A 24-acetate | 98.0% | Unkown | |
| HY-P10336 | Serpinin | Agonist | 98.74% | Unkown |
| HY-142209 | ABBV-167 | Inhibitor | 98.10% | Unkown |
| HY-132307 | Mcl-1 inhibitor 6 | 98.77% | Unkown | |
| HY-16967 | MM41 | 98.89% | Unkown | |
| HY-101083 | BDA-366 | Antagonist | 98.42% | Unkown |
| HY-147929 | Apoptotic agent-3 | 98.19% | Unkown | |
| HY-169265 | BRD-K20733377 | Inhibitor | 99.50% | Unkown |
| HY-N6812 | Karacoline | 99.58% | Unkown | |
| HY-167881 | MLS-0053105 | Inhibitor | 98.89% | Unkown |
| HY-138697 | S65487 | 99.91% | Unkown | |
| HY-10087S | Navitoclax-d8 | 99.71% | Unkown | |
| HY-111329 | JGB1741 | 99.37% | Unkown | |
| HY-129702 | MCL-1/BCL-2-IN-4 | Inhibitor | 99.95% | Unkown |
| HY-147785 | Pim-1 kinase inhibitor 2 | 99.91% | Unkown | |
| HY-156096 | HDAC3-IN-2 | / | Unkown | |
| HY-158208 | PMMB276 | Inhibitor | 99.81% | Unkown |
| HY-161100 | BDM19 | Inducer | 99.38% | Unkown |
| HY-B1752 | Quinpirole | 98.95% | Unkown | |
| HY-N0320 | Salvianolic acid D | 95.15% | Unkown | |
| HY-N1157 | Thevetiaflavone | 99.83% | Unkown | |
| HY-N1423B | Glycocholic acid hydrate | 99.85% | Unkown | |
| HY-N7653 | Azaleatin | 98.86% | Unkown | |
| HY-N7905 | Myricetin 3'-glucoside | Inhibitor | 99.98% | Unkown |
| HY-N0882 | Desacetylcinobufotalin | 99.41% | Unkown | |
| HY-N1414A | 3′,6-Disinapoylsucrose | Inhibitor | 98.88% | Unkown |
| HY-N1930 | (-)-Hinesol | Inducer | 98.7% | Unkown |
| HY-Y0315S | 2,5-Hexanedione-d10 | 99.43% | Unkown | |
| HY-111837 | BI1071 | 98.93% | Unkown | |
| HY-119979 | Cardanol monoene | Inducer | 99.51% | Unkown |
| HY-135273 | A-1211212 | 98.43% | Unkown | |
| HY-161254 | ATPase-IN-3 | 99.89% | Unkown | |
| HY-169925 | BM-962 | Inhibitor | 99.10% | Unkown |
| HY-170820 | XYD049 | Inhibitor | 99.46% | Unkown |
| HY-B1900R | Methylprednisolone succinate (Standard) | 98.90% | Unkown | |
| HY-N4238 | Dehydrocorydaline nitrate | 99.89% | Unkown | |
| HY-109617 | 4-(4-Fluorophenyl)benzoic acid | 99.01% | Unkown | |
| HY-N13250 | Hawthorn Extract | / | Unkown | |
| HY-N4308 | Hexamethylquercetagetin | Inhibitor | 98.0% | Unkown |
| HY-RS01415 | BCL2 Human Pre-designed siRNA Set A | / | Unkown | |
| HY-W075770 | Nickel(II) oxide | ≥99.0% | Unkown | |
| HY-10087A1 | Navitoclax dihydrochloride | 99.15% | Unkown | |
| HY-138697B | S65487 hydrochloride | 98.54% | Unkown | |
| HY-19551 | Apogossypolone | 98.58% | Unkown | |
| HY-119833 | Rubone | Modulator | 99.1% | Unkown |
| HY-129179B | (Rac)-Lisaftoclax | Inhibitor | 98.22% | Unkown |
| HY-129488 | FPFS-1169 hydrochloride | Agonist | 99.83% | Unkown |
| HY-129701 | MCL-1/BCL-2-IN-3 | Inhibitor | 98.93% | Unkown |
| HY-133772 | Venetoclax N-oxide | 99.66% | Unkown | |
| HY-13408 | (+)-Apogossypol | Inhibitor | / | Unkown |
| HY-160108 | Bcl-2-IN-17 | Inhibitor | / | Unkown |
| HY-160921 | Capeserod | Agonist | 98.66% | Unkown |
| HY-161276 | BFC1108 | Inducer | 98.11% | Unkown |
| HY-161659 | Apoptosis inducer 19 | 98.31% | Unkown | |
| HY-174873 | AF151 | 98.87% | Unkown | |
| HY-N10144 | Shinpterocarpin | Inhibitor | / | Unkown |
| HY-N1423S1 | Glycocholic acid-d5 | 99.9% | Unkown | |
| HY-N1983R | Caudatin (Standard) | Inducer | 99.31% | Unkown |
| HY-N2199 | Sotetsuflavone | 96.75% | Unkown | |
| HY-N6690 | Destruxin B | 99.86% | Unkown | |
| HY-P1733 | BMf-BH3 | 99.48% | Unkown | |
| HY-P5325A | Bid BH3 (80-99) acetate | 98.13% | Unkown | |
| HY-RS01431 | BCL2L13 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-W017982A | CMIT/MIT (2.0-2.5% in water) | / | Unkown | |
| HY-W073128 | Perfluorotetradecanoic acid | 98.0% | Unkown | |
| HY-W674241A | 4-Ethylphenyl sulfate sodium | Inducer | / | Unkown |
| HY-15191B | (S)-Sabutoclax | Inhibitor | 98.03% | Unkown |
| HY-B1559 | Allethrin | Inducer | 98.04% | Unkown |
| HY-N1218 | Stellasterol | Inhibitor | / | Unkown |
| HY-N16483 | Procyanidin B2-3'-O-gallate | / | Unkown | |
| HY-RS01421 | BCL2L1 Human Pre-designed siRNA Set A | / | Unkown | |
| HY-114310 | VDR agonist 1 | / | Unkown | |
| HY-131247 | Bcl-2-IN-2 | Inhibitor | / | Unkown |
| HY-155188 | NWP-0476 | Inhibitor | / | Unkown |
| HY-100762 | Mcl1-IN-11 | Inhibitor | / | Unkown |
| HY-100763 | Mcl1-IN-12 | Inhibitor | / | Unkown |
| HY-146097 | RMS5 | / | Unkown | |
| HY-149918 | Antiproliferative agent-23 | / | Unkown | |
| HY-18106 | BM 957 | Inhibitor | / | Unkown |
| HY-184107 | Bcl-2-IN-25 | Inhibitor | / | Unkown |
| HY-78036R | Mesaconic acid (Standard) | Inhibitor | / | Unkown |
| HY-101999 | EM20-25 | / | Unkown | |
| HY-107272 | Chuanbeinone | / | Unkown | |
| HY-107835R | Flumethrin (Standard) | / | Unkown | |
| HY-107835S | Flumethrin-d5 | / | Unkown | |
| HY-115974 | GRPR antagonist-1 | 99.80% | Unkown | |
| HY-116204 | SKLB70326 | / | Unkown | |
| HY-116267 | MHY219 | / | Unkown | |
| HY-117171 | Proquinazid | / | Unkown | |
| HY-119062 | A-800141 | Inhibitor | / | Unkown |
| HY-121934 | BH3I-2' | / | Unkown | |
| HY-123020 | CYD-2-88 | Antagonist | 98.52% | Unkown |
| HY-123034 | CDKI-83 | / | Unkown | |
| HY-123244 | YC137 | / | Unkown | |
| HY-123715 | Anticancer agent 255 | / | Unkown | |
| HY-124122 | BPTQ | / | Unkown | |
| HY-124792 | MRLB-223 | / | Unkown | |
| HY-125191 | BRD1991 | Inhibitor | / | Unkown |
| HY-126311 | 4-Hydroxyresveratrol | Inducer | / | Unkown |
| HY-127130 | Spicamycin | / | Unkown | |
| HY-131188 | PROTAC Bcl-xL degrader-1 | Inhibitor | / | Unkown |
| HY-131405 | β-Eleostearic acid | Inhibitor | / | Unkown |
| HY-135275 | BCL-XL-IN-4 | Inhibitor | / | Unkown |
| HY-136778 | INH2BP | / | Unkown | |
| HY-13846 | BM-1074 | / | Unkown | |
| HY-143235 | BRD4 Inhibitor-15 | / | Unkown | |
| HY-143872 | Bcl-2-IN-4 | Inhibitor | / | Unkown |
| HY-143873 | Bcl-2-IN-5 | Inhibitor | / | Unkown |
| HY-144428 | Bcl-2/Mcl-1-IN-2 | Inhibitor | / | Unkown |
| HY-144430 | Bcl-2/Mcl-1-IN-1 | Inhibitor | / | Unkown |
| HY-144431 | Bcl-2/Mcl-1-IN-3 | Inhibitor | / | Unkown |
| HY-144778 | IDO1/TDO-IN-1 | / | Unkown | |
| HY-144791 | Bcl-2-IN-6 | / | Unkown | |
| HY-144792 | Bcl-2-IN-7 | / | Unkown | |
| HY-145288 | Antitumor agent-36 | / | Unkown | |
| HY-145289 | Antitumor agent-37 | / | Unkown | |
| HY-146095 | p53 Activator 2 | / | Unkown | |
| HY-146253 | CDK1/2/4-IN-1 | / | Unkown | |
| HY-146444 | Anticancer agent 56 | / | Unkown | |
| HY-146471 | EGFR-IN-51 | / | Unkown | |
| HY-146472 | EGFR-IN-52 | / | Unkown | |
| HY-146817 | Tubulin polymerization-IN-11 | / | Unkown | |
| HY-147504 | Anticancer agent 63 | / | Unkown | |
| HY-147826 | EGFR-IN-60 | / | Unkown | |
| HY-147906 | Anticancer agent 71 | / | Unkown | |
| HY-147928 | Apoptotic agent-2 | / | Unkown | |
| HY-149009 | Bcl-2-IN-9 | / | Unkown | |
| HY-149024 | VEGFR-2-IN-23 | / | Unkown | |
| HY-149436 | CDK2/Bcl2-IN-1 | Inhibitor | / | Unkown |
| HY-149517 | EGFR/BRAFV600E-IN-2 | / | Unkown | |
| HY-149622 | Bcl-2-IN-12 | Inhibitor | / | Unkown |
| HY-149623 | Bcl-2-IN-13 | Inhibitor | / | Unkown |
| HY-149624 | Bcl-2-IN-14 | Inhibitor | / | Unkown |
| HY-149625 | Bcl-2-IN-15 | Inhibitor | / | Unkown |
| HY-149681 | Beclin1-Bcl-2 interaction inhibitor 1 | Inhibitor | / | Unkown |
| HY-150540 | Bcl-2-IN-10 | / | Unkown | |
| HY-150596 | CT1-3 | / | Unkown | |
| HY-151428 | Antitumor agent-78 | / | Unkown | |
| HY-151429 | Antitumor agent-77 | / | Unkown | |
| HY-151443 | HDAC-IN-47 | Inhibitor | / | Unkown |
| HY-153494 | Rosomidnar | Inhibitor | / | Unkown |
| HY-153494A | Rosomidnar sodium | Inhibitor | / | Unkown |
| HY-153953 | Bcl-2-IN-11 | Inhibitor | / | Unkown |
| HY-155242 | VEGFR-2-IN-36 | / | Unkown | |
| HY-158551 | PROTAC BcI-2/BcI-xI Degrader-1 | Degrader | / | Unkown |
| HY-159513 | Bcl-2/Mcl-1-IN-4 | Inhibitor | / | Unkown |
| HY-159668 | DL002 | / | Unkown | |
| HY-159817 | Asaretoclax | Inhibitor | / | Unkown |
| HY-159938 | p38α inhibitor 6 | / | Unkown | |
| HY-161415 | BCL-xL/BCL-2 ligand 1 | / | Unkown | |
| HY-161577 | BFC1103 | / | Unkown | |
| HY-161732 | GQN-B37-E | Inhibitor | / | Unkown |
| HY-161786 | Bcl-2-IN-20 | / | Unkown | |
| HY-162148 | HNPMI | Inhibitor | 99.57% | Unkown |
| HY-162820 | Bcl-2-IN-21 | Inhibitor | / | Unkown |
| HY-162826 | Apoptosis inducer 27 | Inducer | / | Unkown |
| HY-162886 | BSO-07 | Activator | / | Unkown |
| HY-163077 | Anticancer agent 175 | Inducer | / | Unkown |
| HY-163308 | Bcl-2-IN-18 | Inhibitor | / | Unkown |
| HY-163309 | Bcl-2-IN-19 | Inhibitor | / | Unkown |
| HY-163435 | Anticancer agent 201 | / | Unkown | |
| HY-163527 | FGFR-IN-13 | Inhibitor | / | Unkown |
| HY-163764 | Bfl-1-IN-4 | / | Unkown | |
| HY-167237 | Calactin | / | Unkown | |
| HY-167825 | Barakol | / | Unkown | |
| HY-168171 | ERK1/2 inhibitor 11 | / | Unkown | |
| HY-168483 | FTO-IN-13 | / | Unkown | |
| HY-168623 | EGFR-IN-134 | / | Unkown | |
| HY-169083 | Bcl-2-IN-22 | Inhibitor | / | Unkown |
| HY-169096 | DPP-21 | / | Unkown | |
| HY-169124 | Apoptosis inducer 28 | / | Unkown | |
| HY-169267 | BRD-K44839765 | Inhibitor | / | Unkown |
| HY-169412 | MAPK-IN-3 | / | Unkown | |
| HY-169431 | VEGFR-2/AKT-IN-2 | / | Unkown | |
| HY-170366 | VEGFR-2-IN-58 | / | Unkown | |
| HY-170648 | TS-IN-5 | / | Unkown | |
| HY-170689 | CG-3-246 | Inhibitor | / | Unkown |
| HY-170787 | TZEP7 | / | Unkown | |
| HY-170929 | EMT inhibitor-3 | / | Unkown | |
| HY-170932 | EGFR/COX-2-IN-1 | / | Unkown | |
| HY-170946 | WR-S-462 | Inhibitor | / | Unkown |
| HY-172092 | BG11 | Inducer | / | Unkown |
| HY-172393 | TCF4/β-catenin-IN-1 | / | Unkown | |
| HY-172394 | ZSNI-21 | / | Unkown | |
| HY-172551 | anti-TNBC agent-9 | / | Unkown | |
| HY-172623 | EGFR/HER2-IN-17 | / | Unkown | |
| HY-172886 | PI3K-IN-58 | / | Unkown | |
| HY-173365 | VEGFR-2-IN-67 | Inhibitor | / | Unkown |
| HY-174232 | EGFR/CA-IX-IN-1 | / | Unkown | |
| HY-174338 | GPER/Bcl-2-IN-1 | Inhibitor | / | Unkown |
| HY-174403 | c-MYC/BCL2 ligand 1 iodide | / | Unkown | |
| HY-174404 | Topoisomerase II inhibitor 23 | / | Unkown | |
| HY-174419 | TFSeB | / | Unkown | |
| HY-174469 | PROTAC PI3K/110β degrader-2 | / | Unkown | |
| HY-174855 | PI3K/mTOR-IN-17 | / | Unkown | |
| HY-174992 | Apoptosis inducer 39 | Inducer | / | Unkown |
| HY-175010 | STAT3-IN-44 | / | Unkown | |
| HY-175021 | HDAC-IN-91 | / | Unkown | |
| HY-175034 | Topoisomerase I/II-IN-1 | / | Unkown | |
| HY-175037 | DNH28 | / | Unkown | |
| HY-175227 | STAT3/NF-κB-IN-1 | / | Unkown | |
| HY-175317 | Nogo-B-IN-1 | / | Unkown | |
| HY-175332 | Apoptosis inducer 43 | / | Unkown | |
| HY-175397 | Dth | / | Unkown | |
| HY-175588 | EGFR-IN-170 | / | Unkown | |
| HY-175638 | Carbonic anhydrase-IN-35 | / | Unkown | |
| HY-175771 | STAT3-IN-46 | Inhibitor | / | Unkown |
| HY-175815 | Apoptosis inducer 44 | / | Unkown | |
| HY-175841 | Tau Protein Phosphorylation-IN-1 | Inhibitor | / | Unkown |
| HY-175848 | NSC 850745 | / | Unkown | |
| HY-176219 | Bcl-2-IN-23 | / | Unkown | |
| HY-176279 | Hsp90-IN-42 | / | Unkown | |
| HY-17662 | Mol4 | Inhibitor | / | Unkown |
| HY-177076 | Dalvotoclax | Inhibitor | / | Unkown |
| HY-177208 | BW-AQ-113 | / | Unkown | |
| HY-178008 | Mcl-1-IN-16 | / | Unkown | |
| HY-178036 | ZM484 | Inhibitor | / | Unkown |
| HY-178099 | Apoptosis inducer 45 | / | Unkown | |
| HY-178176 | PROTAC CB1R Degrader-1 | / | Unkown | |
| HY-178351 | HDAC6-IN-67 | / | Unkown | |
| HY-178373 | Topoisomerase I-IN-18 | / | Unkown | |
| HY-178380 | HDAC8-IN-14 | / | Unkown | |
| HY-178446 | METTL3-IN-11 | Inhibitor | / | Unkown |
| HY-178910 | Mcl-1-IN-20 | / | Unkown | |
| HY-178911 | TS-IN-8 | / | Unkown | |
| HY-178940 | Apoptosis inducer 49 | / | Unkown | |
| HY-178942 | EGFR/VEGFR2-IN-9 | / | Unkown | |
| HY-179125 | COX-2-IN-59 | / | Unkown | |
| HY-179155 | PI3K/mTOR-IN-19 | / | Unkown | |
| HY-179161 | CDK2-IN-49 | / | Unkown | |
| HY-179439 | Multi-kinase-IN-8 | / | Unkown | |
| HY-179480 | G-quadruplex ligand 4 | / | Unkown | |
| HY-179485 | EGFR/VEGFR2-IN-10 | / | Unkown | |
| HY-179520 | XSJ151 | / | Unkown | |
| HY-179522 | EGFR-IN-186 | / | Unkown | |
| HY-180154 | EGFR/BRAFV600E-IN-6 | / | Unkown | |
| HY-180190 | Tubulin polymerization-IN-85 | / | Unkown | |
| HY-180196 | EGFR-IN-187 | / | Unkown | |
| HY-180242 | EGFR/CDK2-IN-5 | / | Unkown | |
| HY-180245 | STAT3-IN-51 | / | Unkown | |
| HY-180274 | JAK1/2-IN-3 | / | Unkown | |
| HY-180324 | Candidone | / | Unkown | |
| HY-180618 | p53 DUBTAC modulator-1 | / | Unkown | |
| HY-180820 | Dimethyl bisphenolate | / | Unkown | |
| HY-180823 | Topoisomerase II/EGFR-IN-2 | / | Unkown | |
| HY-180848 | Bcl-2-IN-24 | / | Unkown | |
| HY-181015 | α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu | / | Unkown | |
| HY-181018 | Topo I/DDX5-IN-1 | / | Unkown | |
| HY-181060 | Apoptosis inducer 56 | / | Unkown | |
| HY-181061 | COX/5-LO-IN-2 | / | Unkown | |
| HY-181087 | Anticancer agent 296 | / | Unkown | |
| HY-181174 | Antioxidant agent-22 | / | Unkown | |
| HY-181413 | PROTAC EZH2 Degrader-44 | / | Unkown | |
| HY-181477 | ERK5-IN-7 | / | Unkown | |
| HY-181505 | BRD4-IN-12 | / | Unkown | |
| HY-181673 | ICD inducer-2 | / | Unkown | |
| HY-181723 | Anticancer agent 304 | / | Unkown | |
| HY-181725 | Topoisomerase I-IN-20 | / | Unkown | |
| HY-181746 | Bcl-2/Mcl-1-IN-5 | / | Unkown | |
| HY-181769 | Anticancer agent 306 | / | Unkown | |
| HY-181795 | CSN5-IN-3 | / | Unkown | |
| HY-182060 | PDE4B/D-IN-5 | / | Unkown | |
| HY-182069 | CDK9-IN-47 | / | Unkown | |
| HY-182243 | HK2-IN-4 | 99.85% | Unkown | |
| HY-182284 | Anticancer agent 310 | / | Unkown | |
| HY-182360 | Cytisine-platinum(IV) prodrug-1 | / | Unkown | |
| HY-182469 | FuBIG | / | Unkown | |
| HY-182706 | NSC 373981 | Inhibitor | / | Unkown |
| HY-182745 | VEGFR-2-IN-85 | / | Unkown | |
| HY-182759 | MN33-47 | / | Unkown | |
| HY-182760 | MN33-63 | / | Unkown | |
| HY-182986 | LS-Q2 | / | Unkown | |
| HY-183069 | FKL-137 | / | Unkown | |
| HY-183327 | PI3K/mTOR-IN-22 | Inhibitor | / | Unkown |
| HY-183330 | Topo I/II-IN-3 | / | Unkown | |
| HY-183355 | KRAS G12D-IN-37 | / | Unkown | |
| HY-183369 | VEGFR/PD-L1-IN-1 | / | Unkown | |
| HY-183390 | Scopadulciol | / | Unkown | |
| HY-183791A | Ferroptosis/apoptosis inducer-5 | / | Unkown | |
| HY-184116 | A2AR/EGFR-IN-1 | / | Unkown | |
| HY-184145 | AKT1-IN-13 | / | Unkown | |
| HY-184274 | EGFR/c-SRC-IN-1 | / | Unkown | |
| HY-184302 | Apoptosis inducer 62 | / | Unkown | |
| HY-184386 | Aurora kinase-IN-15 | / | Unkown | |
| HY-184443 | Bcl-2-IN-26 | / | Unkown | |
| HY-184501 | UE01 | / | Unkown | |
| HY-184737 | TPP-C8-CO-DSG bromide | / | Unkown | |
| HY-184891 | W1307 | Inhibitor | / | Unkown |
| HY-185559 | Mito-fisetin mF7 | / | Unkown | |
| HY-186248 | BCS12 | / | Unkown | |
| HY-18628S | UMI-77-d4 | Inhibitor | / | Unkown |
| HY-50907S | ABT-737-d8 | 99.11% | Unkown | |
| HY-B0011AS | Docetaxel-d5 trihydrate | / | Unkown | |
| HY-N0307R | Ciwujianoside B (Standard) | Inhibitor | / | Unkown |
| HY-N0361S | Dihydrocapsaicin-d3 | / | Unkown | |
| HY-N0392R | Polygalasaponin F (Standard) | Inhibitor | / | Unkown |
| HY-N0559R | Kirenol (Standard) | / | Unkown | |
| HY-N0757R | 8-O-Acetylharpagide (Standard) | / | Unkown | |
| HY-N10091 | 2,3-Dihydro-3α-methoxynimbolide | / | Unkown | |
| HY-N10342 | Cajanol | / | Unkown | |
| HY-N1255A | Scoulerine hydrochloride | / | Unkown | |
| HY-N13338 | Avicin D | / | Unkown | |
| HY-N15449 | Vicanicin | / | Unkown | |
| HY-N16771 | Clausenidin | / | Unkown | |
| HY-N16929 | Gymnoside II | / | Unkown | |
| HY-N17440 | 2-Methoxyjuglone | / | Unkown | |
| HY-N17617 | S-Petasin | / | Unkown | |
| HY-N17816 | Tambulin | / | Unkown | |
| HY-N19029 | Vernodalin | / | Unkown | |
| HY-N20627 | Withametelin B | / | Unkown | |
| HY-N2741 | Vitexin B-1 | Inhibitor | / | Unkown |
| HY-N3828 | epi-Eriocalyxin A | / | Unkown | |
| HY-N6799 | Neosolaniol | 99.72% | Unkown | |
| HY-N7917 | Tenacigenoside A | / | Unkown | |
| HY-N9778 | Phoyunbene B | / | Unkown | |
| HY-P10057 | cpm-1285 | Inducer | / | Unkown |
| HY-P10058 | cpm-1285m | / | Unkown | |
| HY-P10614 | Bid BH3 peptide | Inducer | / | Unkown |
| HY-P10614A | Bid BH3 peptide acetate | Inducer | / | Unkown |
| HY-P10833 | C-VGB3 | / | Unkown | |
| HY-P11374 | Bid BH3-Gly-r8 | Ligand | / | Unkown |
| HY-P11707 | FS1 peptide | / | Unkown | |
| HY-P1380 | Difopein | / | Unkown | |
| HY-P1889A | Bim BH3, Peptide IV TFA | / | Unkown | |
| HY-P5324 | Bad BH3 (mouse) | / | Unkown | |
| HY-P5325 | Bid BH3 (80-99) | / | Unkown | |
| HY-P5327 | r8 Bid BH3 | / | Unkown | |
| HY-RS01416 | Bcl2 Mouse Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01417 | BCL2 Rat Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01418 | BCL2A1 Human Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01419 | Bcl2a1 Rat Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01420 | Bcl2a1a Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS01422 | Bcl2l1 Mouse Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01423 | Bcl2l1 Rat Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01424 | BCL2L10 Human Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01425 | Bcl2l10 Mouse Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01426 | Bcl2l10 Rat Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01427 | BCL2L11 Human Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01428 | Bcl2l11 Mouse Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01429 | Bcl2l11 Rat Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01430 | BCL2L12 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS01432 | BCL2L14 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS01433 | BCL2L15 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS01434 | BCL2L2 Human Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01435 | Bcl2l2 Mouse Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01436 | Bcl2l2 Rat Pre-designed siRNA Set A | / | Unkown | |
| HY-W016937 | Moroxydine | Inhibitor | / | Unkown |
| HY-W017370R | Carveol (Standard) | / | Unkown | |
| HY-W713297 | Moroxydine hydrochloride-d8 | Inhibitor | / | Unkown |
| HY-W717425 | SC-60 | / | Unkown | |
| HY-W754548 | Glycocholic acid-13C2,d4 | / | Unkown | |
| HY-101083A | (Rac)-BDA-366 | Inhibitor | / | Unkown |
| HY-115529 | (-)BI97D6 | Inducer | / | Unkown |
| HY-116532 | YCW-E11 | Inhibitor | / | Unkown |
| HY-117136 | AN-7 | / | Unkown | |
| HY-12011A | (Rac)-HA14-1 | Inhibitor | / | Unkown |
| HY-122047 | SW063058 | / | Unkown | |
| HY-136714 | Bcl-2-IN-3 | Inhibitor | / | Unkown |
| HY-15531S1 | Venetoclax-d6 | / | Unkown | |
| HY-164468 | Ch282-5 | Inhibitor | / | Unkown |
| HY-171031 | TFGF-18 | / | Unkown | |
| HY-174635 | Human IL15RA mRNA | / | Unkown | |
| HY-174776 | Human BAX mRNA | / | Unkown | |
| HY-174777 | Human BAK1 mRNA | / | Unkown | |
| HY-181030 | BDE30671203 | / | Unkown | |
| HY-182586 | Decyl gallate | Activator | / | Unkown |
| HY-183402 | FLLL12 | / | Unkown | |
| HY-184378 | MDB5 | / | Unkown | |
| HY-184835 | Uranyl acetate | / | Unkown | |
| HY-N11231 | Fucoxanthinol | / | Unkown | |
| HY-N15136 | Isomorellinol | Inducer | / | Unkown |
| HY-N15315 | Triptriolide | / | Unkown | |
| HY-N15378 | β-Carotene-15,15'-epoxide | / | Unkown | |
| HY-N15466 | Longan cerebroside II | Inhibitor | / | Unkown |
| HY-N18905 | α-D-Glucosyl hesperidin | / | Unkown | |
| HY-N19904 | Rhodomyrtosone D | Inhibitor | / | Unkown |
| HY-N6082R | Rhein 8-O-β-D-Glucopyranoside (Standard) | / | Unkown | |
| HY-N6799R | Neosolaniol (Standard) | / | Unkown | |
| HY-N6926 | 1,3,5-Tricaffeoylquinic acid | / | Unkown | |
| HY-N8579 | Eugenyl benzoate | ≥90.0% | Unkown | |
| HY-RS21989 | Bcl2l12 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS28507 | Bcl2l12 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-W715812 | Bromuconazole | / | Unkown | |
| HY-W747601 | Chlorphoxim | / | Unkown | |
| HY-W751400 | Solasodine hydrochloride | / | Unkown |
Inhibitory Antibodies
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P990344 | Anti-Bcl-2 Antibody | Inhibitor | / | Unkown |
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