Camp - cathelicidin antimicrobial peptide Gene

Also Known as CLP; Cnlp; MCLP; CAP18; Cramp; FALL39

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12796

Summary

This gene encodes a member of the cathelicidin family of antimicrobial peptides that play an important role in the defense against microbial Infection. The encoded preproprotein undergoes proteolytic processing to generate a mature polypeptide before secretion by host cells such as neutrophils, epithelial cells and macrophages. Mice lacking the encoded protein exhibit increased susceptibility to group A streptococcus and Escherichia coli infections. [provided by RefSeq, Oct 2015]

Camp Products (1)

mRNA Protein Name
NM_009921.2 NP_034051.2 cathelicidin antimicrobial peptide precursor
Biological Process GO Annotation Evidence References Source
involved in antimicrobial humoral immune response mediated by antimicrobial peptide IMP
IMP: Inferred from mutant phenotype
17012259 MGI
acts upstream of or within defense response to Gram-negative bacterium IDA
IDA: Inferred from direct assay
9148921 MGI
involved in defense response to Gram-negative bacterium IMP
IMP: Inferred from mutant phenotype
17012259 MGI
acts upstream of or within defense response to Gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
16177355 MGI
involved in defense response to Gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
17012259 MGI
acts upstream of or within defense response to bacterium IMP
IMP: Inferred from mutant phenotype
23670560 MGI
involved in innate immune response IMP
IMP: Inferred from mutant phenotype
17012259 MGI
acts upstream of or within killing by host of symbiont cells IMP
IMP: Inferred from mutant phenotype
16177355 MGI
Cellular Component GO Annotation Evidence References Source
located in specific granule IDA
IDA: Inferred from direct assay
9148921 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cathelicidin antimicrobial peptide

  • cathelin-like protein

  • cathelin-related antimicrobial peptide

Orthologs Information

Species Symbol Source ID
Homo sapiens Camp NCBI NCBI:820