1. Gene
  2. Ar - androgen receptor Gene

Ar - androgen receptor Gene

Rattus norvegicus

Also known as Tfm; Andr

Gene ID: 24208 | Gene type: protein coding

About Ar

Primary_assembly X: 63,104,771-63,273,925 forward strand.mRatBN7.2:CM026994.1

This gene has 1 transcript (splice variant), 277 orthologues, 8 paralogues and is associated with 62 phenotypes. Biased expression in Adrenal (RPKM 352.8), Uterus (RPKM 74.9) and 7 other tissues.

Summary

Enables several functions, including androgen binding activity; Androgen Receptor binding activity; and nuclear receptor activity. Involved in several processes, including cellular response to hormone stimulus; mating; and regulation of transcription, DNA-templated. Located in several cellular components, including axon; dendrite; and nucleus. Used to study hypertension; osteoporosis; prostate adenocarcinoma; prostate cancer; and prostatic hypertrophy. Biomarker of acute kidney failure and androgen insensitivity syndrome. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; conduct disorder; disorder of sexual development (multiple); reproductive organ Cancer (multiple); and spinal muscular atrophy (multiple). Orthologous to human AR (Androgen Receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ar Products(1)

mRNA Protein Name
NM_012502.2 NP_036634.2 androgen receptor

Ar Protein Structure

Androgen_recep

Androgen_recep: cl27454 (5 - 442)

NR_DBD_AR

NR_DBD_AR: cd07173 (536 - 617)

NR_LBD_AR

NR_LBD_AR: cd07073 (654 - 899)

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  • 902 a.a.
Protein Preferred Names Protein Names

androgen receptor

androgen receptor (Testicular feminization), same as Tfm

dihydrotestosterone receptor

nuclear receptor subfamily 3 group C member 4

Orthologs Information

Species Symbol Source ID
Homo sapiens Ar NCBI NCBI:367
Canis familiaris Ar NCBI NCBI:403588
Macaca fascicularis Ar NCBI NCBI:102117720
Canis lupus familiaris Ar NCBI
Mus musculus Ar NCBI NCBI:11835
Susscrofa domestica Ar NCBI
Leporidae Ar NCBI
Macaca mulatta Ar NCBI NCBI:574293