Sars - seryl-aminoacyl-tRNA synthetase Gene

Also Known as Strs; Sars1; serRS

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20226

Summary

Predicted to enable several functions, including nucleic acid binding activity; protein homodimerization activity; and serine-tRNA Ligase activity. Predicted to be involved in negative regulation of angiogenesis; negative regulation of macromolecule metabolic process; and seryl-tRNA aminoacylation. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; egg cylinder; and genitourinary system. Human ortholog(s) of this gene implicated in intellectual disability. Orthologous to human SARS1 (seryl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]

Sars Products (2)

mRNA Protein Name
NM_001204979.1 NP_001191908.1 serine--tRNA ligase, cytoplasmic isoform 2
NM_011319.3 NP_035449.1 serine--tRNA ligase, cytoplasmic isoform 1
Protein Preferred Names Protein Names

serine--tRNA ligase, cytoplasmic

  • seryl-aminoacyl-tRNA synthetase 1

  • seryl-tRNA synthetase, cytoplasmic

  • seryl-tRNA(Ser/Sec) synthetase