PI3 - peptidase inhibitor 3 Gene

Homo sapiens

Also known as ESI; WAP3; SKALP; WFDC14; cementoin

Gene ID: 5266 | Gene type: protein coding

About PI3

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:45,174,902-45,176,544 (from NCBI)

This gene has 1 transcript (splice variant), 80 orthologues and 9 paralogues. Biased expression in esophagus (RPKM 578.7), colon (RPKM 50.5) and 1 other tissue.

Summary

This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and Fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by Bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014]

PI3 Products(1)

mRNA	Protein	Name
NM_002638.4	NP_002629.1	elafin preproprotein

PI3 Protein Structure

Cementoin

WAP

0
100
117 a.a.

Protein Preferred Names

Protein Names

elafin

PI-3

Recombinant PI3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70316	Elafin/Trappin-2 Protein, Human (HEK293, His)	P19957 (A23-Q117)	≥95%

Related Diseases

Diseases

Alias

Pustular Psoriasis

Farmer'S Lung

Farmer Lung	Farmers Lung
Farmer'S Lung Disease	Farmers' Lung
Farmers' Lung Disease	Mouldy Hay Disease
Moldy Hay Disorder	Fibrosis Of Lung With Farmers' Lung
Harvesters' Hypersensitivity Pneumonitis	Moldy Hay Pneumoconiosis
Haymakers' Hypersensitivity Pneumonitis	Threshers' Lung
Harvester Lung	Haymaker Lung

Extrinsic Allergic Alveolitis

Hypersensitivity Pneumonitis	Alveolitis, Extrinsic Allergic
Alveolitis	Allergic Interstitial Pneumonitis
Allergic Pneumonitis	Extrinsic Allergic Pneumonia Hypersensitivity Pneumonitis
Hp	Pneumonitis Hypersensitivity
Allergic Alveolitis	Extrinsic Allergic Alveolitis Nos
Airway Obstruction With Allergic Alveolitis	Unspecified Allergic Alveolitis And Pneumonitis
Extrinsic Allergic Bronchiolo-Alveolitis	Hypersensitivity Pneumonia
Hypersensitivity Pneumonitis Nos	Obstructive Lung Disease With Allergic Alveolitis
Obstructive Lung Disorder With Hypersensitivity Pneumonitis	Obstructive Lung Disorder With Allergic Alveolitis
Obstructive Lung Disease With Hypersensitivity Pneumonitis

Erysipelas

Adult Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome	Ards
Non-Cardiogenic Pulmonary Edema	Acute Lung Injury
Respiratory Distress Syndrome, Adult	Shock Lung
Acute Respiratory Distress	Respiratory Distress Syndrome
Adult Rds	Ali
Increased-Permeability Pulmonary Edema	Stiff Lung
Respiratory Distress Syndrome Adult

Impetigo

Netherton Syndrome

NETH	Ns
Netherton Disease	Comel-Netherton Syndrome
Erythroderma, Ichthyosiform, With Hypotrichosis And Hyper-Ige	Bamboo Hair Syndrome
Ichthyosis Linearis Circumflexa	Ichthyosiform Erythroderma With Hypotrichosis And Hyper-Ige
Ilc	Nts
N Syndrome

Allergic Contact Dermatitis

Dermatitis, Allergic Contact	Contact Dermatitis, Allergic
Dermatitis Allergic Contact	Allergic Contact Eczema
Acd - [Allergic Contact Dermatitis]	Allergic Contact Dermatitis, Unspecified Cause
Allergic Dermatitis	Allergic Eczema
Allergy Dermatitis	Allergy Eczema
Allergic Contact Eczema Due To Clothing Or Footwear	Perfume Allergic Contact Dermatitis
Allergic Contact Dermatitis Due To Cosmetics	Allergic Contact Eczema Due To Cosmetics Or Fragrances
Allergic Contact Eczema Due To Dental Materials	Allergic Contact Eczema Due To Food Flavours Or Additives
Allergic Contact Eczema Due To Hairdressing Products	Allergic Contact Eczema Due To Metals Or Metal Salts
Allergic Contact Eczema Due To Proteins	Allergic Contact Eczema Due To Plastics Or Resin Systems
Allergic Contact Eczema Due To Preservatives Or Biocides	Allergic Contact Eczema Due To Rubber Chemicals
Rubber Dermatitis	Allergic Contact Eczema Due To Systemic Medicaments
Allergic Contact Eczema Due To Topical Medicaments	Allergic Contact Dermatitis Due To Drugs In Contact With Skin

Lung Disease

Lung Diseases	Disorder Of Lung
Abnormality Of The Lung

Psoriasis

Corneal Abscess

Double Pterygium

Pasteurellosis

Pasteurella Infection	Pasteurella Infections
Pasteurella Infectious Disease	Shipping Fever
Transport Fever

Skin Disease

Skin Diseases	Genodermatosis
Abnormality Of The Skin	Skin Diseases, Genetic
Skin And Subcutaneous Tissue Disease	Dermatologic Disorders

Cystic Fibrosis

Mucoviscidosis	CF
Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis	Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis
Cystic Fibrosis Lung Disease, Modifier Of	Cystic Fibrosis Of Pancreas
Fibrocystic Disease Of Pancreas	Cf - [Cystic Fibrosis]
Cystic Fibrosis Nos	Fibrocystic Disease
Fibrocystic Disease Of The Pancreas	Mucoviscidosis Of Pancreas
Nonproliferative Fibrocystic Disease	Pancreatic Cystic Fibrosis

Familiar Ovarian Carcinoma

Bacterial Infectious Disease

Bacterial Infections	Bacterial Infection Nos
Disease Caused By Bacteria	Bacterial Disease Or Disorder

Type 1 Diabetes Mellitus 8

Diabetes Mellitus, Insulin-Dependent, 8	Iddm8
Insulin-Dependent Diabetes Mellitus 8	T1D8
Insulin-Dependent Diabetes Mellitus-8

Preterm Premature Rupture Of The Membranes

Preterm Premature Rupture Of Membranes	PPROM
Preterm Premature Rupture Of The Membranes, Susceptibility To	Pprom - [Preterm Premature Rupture Of Membranes]
Preterm Rupture Of Membranes

Pulmonary Disease, Chronic Obstructive

Chronic Obstructive Pulmonary Disease	COPD
Pulmonary Disease, Chronic Obstructive, Severe Early-Onset	Chronic Obstructive Lung Disease
Chronic Obstructive Airway Disease	Pulmonary Disease, Chronic Obstructive, Susceptibility To
Cold	Severe Early-Onset Chronic Obstructive Pulmonary Disease
Pulmonary Disease Chronic Obstructive	Pulmonary Disease, Obstructive, Chronic, Susceptibility To
Chronic Obstructive Pulmonary Disease Of Horses	Common Cold
Upper Respiratory Infections	Copd - [Chronic Obstructive Pulmonary Disease]
Coad - [Chronic Obstructive Airways Disease]	Cold - [Chronic Obstructive Lung Disease]
Chronic Airway Disease Nos	Chronic Airways Limitation, Unspecified
Chronic Obstructed Airway, Unspecified	Chronic Obstructive Airway Disease, Unspecified
Chronic Obstructive Airway, Unspecified	Obstructive Lung Disease Nos
Chronic Obstructive Lung Disease Nos	Chronic Obstructive Lung Nos
Obstructive Pulmonary Disease Nos	Exacerbation Copd Nos
Acute Exacerbation Copd

Parotid Gland Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma Of Parotid Gland

Joubert Syndrome 7

JBTS7	Cerebello-Oculo-Renal Syndrome 3
Cors3	Joubert Syndrome, Type 7

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Basal Cell Carcinoma

Basal Cell Cancer	Basal Cell Neoplasm
Basal Cell Carcinoma Of Skin	Malignant Basal Cell Tumor
Basal Cell Tumor	Epithelioma Basal Cell
Malignant Basal Cell Neoplasm	Rodent Ulcer
Carcinoma Basal Cell	Neoplasms, Basal Cell
Basal Cell Carcinomas	Experimental Organism Basal Cell Carcinoma
Nodulo-Ulcerative Basal Cell Carcinoma	Basalioma
Basal Cell Epithelioma Of Skin	Bcc - [Basal Cell Carcinoma] Of Skin
Rodent Ulcer Of Skin	Rodent Ulcer Of Unspecified Site
Basal Cell Epithelioma Of Unspecified Site

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval

Bioactive Molecules (24)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15244	Alpelisib	Inhibitor	99.95%	Yes
HY-15346	Copanlisib		99.50%	Unkown
HY-13026	Idelalisib		99.78%	Yes
HY-17508	Clarithromycin	Inhibitor	99.90%	Yes
HY-15346A	Copanlisib dihydrochloride		99.55%	Yes
HY-12279	Umbralisib	Inhibitor	98.69%	Yes
HY-13685	Miltefosine	Inhibitor	≥98.0%	Yes
HY-B0965	Thioridazine hydrochloride		99.96%	Unkown
HY-B0648	Medroxyprogesterone	Agonist	99.30%	Unkown
HY-14153A	Tegaserod maleate		99.93%	Unkown
HY-14151	Prucalopride		99.83%	Yes
HY-17635	Leniolisib	Inhibitor	99.19%	Yes
HY-15856B	Flupentixol dihydrochloride		99.73%	Yes
HY-12694	Prucalopride succinate		99.95%	Yes
HY-14153	Tegaserod		99.89%	Unkown
HY-12279C	Umbralisib hydrochloride	Inhibitor	98.98%	Yes
HY-12279A	Umbralisib tosylate	Inhibitor	/	Unkown
HY-12279B	Umbralisib sulfate	Inhibitor	/	Unkown
HY-15244A	Alpelisib hydrochloride	Inhibitor	/	Unkown
HY-15856BR	Flupentixol dihydrochloride (Standard)		/	Unkown
HY-17508R	Clarithromycin (Standard)	Inhibitor	/	Unkown
HY-B0965R	Thioridazine hydrochloride (Standard)		/	Unkown
HY-15856A	Flupentixol		/	Unkown
HY-B0965A	Thioridazine		/	Unkown

Clinical Phase

Bioactive Molecules (66)

Cat. No.	Product Name	Effect	Purity	Phase
HY-18085	Quercetin		98.06%	Phase 4
HY-N0146	Quercetin dihydrate		≥97.0%	Phase 4
HY-18085G	Quercetin (GMP)		/	Phase 4
HY-70063	Buparlisib		99.90%	Phase 3
HY-50673	Dactolisib		99.94%	Phase 3
HY-101562	Inavolisib		99.85%	Phase 3
HY-13898	Taselisib	Inhibitor	99.86%	Phase 3
HY-12037A	Rigosertib		98.35%	Phase 3
HY-N0104	Curcumol	Inducer	99.50%	Phase 3
HY-12037	Rigosertib sodium		99.57%	Phase 3
HY-D0803	Thymoquinone		99.59%	Phase 3
HY-15174	Dactolisib Tosylate		99.87%	Phase 3
HY-109068	Parsaclisib	Inhibitor	99.31%	Phase 3
HY-109198	Zandelisib	Inhibitor	99.90%	Phase 3
HY-15180	Buparlisib Hydrochloride		99.88%	Phase 3
HY-17635A	Leniolisib phosphate	Inhibitor	99.10%	Phase 3
HY-109068A	Parsaclisib hydrochloride	Inhibitor	98.74%	Phase 3
HY-50094	Pictilisib		99.80%	Phase 2
HY-100716	Eganelisib	Inhibitor	99.69%	Phase 2
HY-139609	Camonsertib	Inhibitor	99.75%	Phase 2
HY-19719	Miransertib	Inhibitor	99.32%	Phase 2
HY-13522	Fimepinostat		99.95%	Phase 2
HY-15245	GSK2636771	Inhibitor	99.83%	Phase 2
HY-15177	PF-04691502		99.91%	Phase 2
HY-12330	AZD8186	Inhibitor	99.97%	Phase 2
HY-12513	Samotolisib		99.42%	Phase 2
HY-15900	Voxtalisib	Inhibitor	98.81%	Phase 2
HY-10111	TG100-115	Inhibitor	99.01%	Phase 2
HY-13246	Apitolisib		99.65%	Phase 2
HY-12868	Bimiralisib	Inhibitor	99.80%	Phase 2
HY-N6775	Sonolisib	Inhibitor	99.00%	Phase 2
HY-102031	Linperlisib	Inhibitor	99.51%	Phase 2
HY-13334	BGT226 maleate		99.87%	Phase 2
HY-19535A	Nemiralisib	Inhibitor	99.80%	Phase 2
HY-10202	Tandutinib		99.48%	Phase 2
HY-12948	AMG319	Inhibitor	99.08%	Phase 2
HY-13334A	BGT226		99.51%	Phase 2
HY-16526	Pilaralisib	Inhibitor	99.69%	Phase 2
HY-16754	Seletalisib	Inhibitor	98.88%	Phase 2
HY-20180	Pictilisib dimethanesulfonate		99.70%	Phase 2
HY-123938	Risovalisib	Inhibitor	99.39%	Phase 2
HY-P0118A	Disitertide TFA		/	Phase 2
HY-132601	Cobomarsen	Inhibitor	92.58%	Phase 2
HY-19719A	Miransertib hydrochloride	Inhibitor	99.74%	Phase 2
HY-123938A	CYH33 methanesulfonate	Inhibitor	96.76%	Phase 2
HY-10202A	Tandutinib hydrochloride		99.78%	Phase 2
HY-P0118	Disitertide		/	Phase 2
HY-123823	Nitroaspirin		/	Phase 2
HY-10220	SF1126	Inducer	/	Phase 2
HY-109029	Dezapelisib	Inhibitor	/	Phase 2
HY-19535	Nemiralisib hydrochloride		/	Phase 2
HY-101625	Recilisib	Activator	99.14%	Phase 1
HY-10297	Omipalisib		99.93%	Phase 1
HY-50847	ZSTK474		99.88%	Phase 1
HY-N2037A	Higenamine hydrochloride		99.68%	Phase 1
HY-19896	COTI-2		99.66%	Phase 1
HY-12036	GSK1059615		≥99.0%	Phase 1
HY-16585	VS-5584	Inhibitor	99.14%	Phase 1
HY-17645	Tenalisib	Inhibitor	98.83%	Phase 1
HY-15837	SAR-260301	Inhibitor	99.95%	Phase 1
HY-12644	Acalisib	Inhibitor	99.98%	Phase 1
HY-100886	BAY1082439		98.02%	Phase 1
HY-15466	Izorlisib	Inhibitor	98.93%	Phase 1
HY-121246	Fluorofenidone		99.65%	Phase 1
HY-101625A	Recilisib sodium	Activator	/	Phase 1
HY-100694	GS-9901		99.97%	Phase 1

Pre-clinical Phase

Bioactive Molecules (397)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-19312	3-Methyladenine	Inhibitor	99.91%	Unkown
HY-10108	LY294002		99.95%	Unkown
HY-P0175	740 Y-P		99.67%	Unkown
HY-10197	Wortmannin	Inhibitor	99.86%	Unkown
HY-12016	KU-55933	Inhibitor	99.88%	Unkown
HY-11006	KU-57788		99.73%	Unkown
HY-12481	SAR405	Inhibitor	98.99%	Unkown
HY-13002	Torin 2		99.98%	Unkown
HY-N0728	α-Linolenic acid	Inhibitor	99.59%	Unkown
HY-N0776	Isorhamnetin	Inhibitor	99.95%	Unkown
HY-10115	PI-103		98.93%	Unkown
HY-131615	TPC2-A1-P	Agonist	99.76%	Unkown
HY-12795	Vps34-IN-1		99.56%	Unkown
HY-15719	NU 7026		99.86%	Unkown
HY-N0451	Acacetin	Inducer	99.84%	Unkown
HY-124719	hSMG-1 inhibitor 11j	Inhibitor	99.81%	Unkown
HY-110171	iMDK	Inhibitor	99.34%	Unkown
HY-D0254	Gallein		≥98.0%	Unkown
HY-13425	Deguelin		99.72%	Unkown
HY-10114	TGX-221	Inhibitor	99.74%	Unkown
HY-156681	STX-478	Inhibitor	99.60%	Unkown
HY-10681	Gedatolisib	Inhibitor	99.68%	Unkown
HY-151527	PI3K/Akt/CREB activator 1		99.10%	Unkown
HY-15477	YS-49		99.92%	Unkown
HY-154848	UCL-TRO-1938	Activator	99.56%	Unkown
HY-N0284	Esculetin	Inhibitor	99.59%	Unkown
HY-12030	PIK-90	Inhibitor	99.70%	Unkown
HY-N0457	Chicoric acid	Inducer	99.95%	Unkown
HY-12046	PIK-93	Inhibitor	99.81%	Unkown
HY-12794	Vps34-PIK-III	Inhibitor	99.02%	Unkown
HY-N0787	Cryptochlorogenic acid		99.88%	Unkown
HY-16596	CNX-1351	Inhibitor	99.88%	Unkown
HY-N2515	Ginsenoside Rk1		99.90%	Unkown
HY-N1381	Periplocin		99.92%	Unkown
HY-N1435	Oroxin B		99.71%	Unkown
HY-124760	hSMG-1 inhibitor 11e	Inhibitor	99.81%	Unkown
HY-N0076	Bilobalide	Inhibitor	≥98.0%	Unkown
HY-10109	AS-605240		98.51%	Unkown
HY-153306	RLY-2608	Inhibitor	99.20%	Unkown
HY-N0361	Dihydrocapsaicin		99.86%	Unkown
HY-15290	AIM-100	Inhibitor	99.95%	Unkown
HY-P0118B	Disitertide diammonium		99.53%	Unkown
HY-P1925A	GO-203 TFA		99.28%	Unkown
HY-10044	WYE-132		99.40%	Unkown
HY-144806	PI3K/AKT-IN-1		99.62%	Unkown
HY-103450	G36	Antagonist	99.66%	Unkown
HY-N0103	Sophocarpine		98.63%	Unkown
HY-116035	Nimbolide		99.94%	Unkown
HY-18676	OSU-T315		99.88%	Unkown
HY-10110	IC-87114	Inhibitor	99.83%	Unkown
HY-12068	PI3K-IN-1	Inhibitor	99.93%	Unkown
HY-N1346	Robinin		98.77%	Unkown
HY-13532	AS-252424	Inhibitor	99.71%	Unkown
HY-14971	(E)-Akt inhibitor-IV	Inhibitor	99.89%	Unkown
HY-122862	RAS inhibitor Abd-7	Inhibitor	99.16%	Unkown
HY-110171A	iMDK quarterhydrate	Inhibitor	99.34%	Unkown
HY-13431	KU-0060648	Inhibitor	99.62%	Unkown
HY-11002	CP-466722	Inhibitor	99.91%	Unkown
HY-N2447	Amarogentin		98.96%	Unkown
HY-P2196A	ELA-32(human) TFA	Agonist	99.27%	Unkown
HY-10683	PKI-402	Inhibitor	98.43%	Unkown
HY-N2045	Musk ketone		99.41%	Unkown
HY-146751	PI3K/Akt/mTOR-IN-2		99.86%	Unkown
HY-107365	PQR530	Inhibitor	99.98%	Unkown
HY-117163	FzM1.8	Agonist	98.37%	Unkown
HY-141807	MS21		99.88%	Unkown
HY-143404	PI3K-IN-30	Inhibitor	98.21%	Unkown
HY-N6002	3'-Hydroxypterostilbene	Inducer	99.46%	Unkown
HY-19798	PI4KIIIbeta-IN-9	Inhibitor	99.01%	Unkown
HY-12034	WYE-354		98.04%	Unkown
HY-15868	HS-173		99.04%	Unkown
HY-150795	SY-LB-35		≥98.0%	Unkown
HY-12235	PI-3065	Inhibitor	98.97%	Unkown
HY-N2187	Deoxyshikonin		99.96%	Unkown
HY-101272	GDC-0326	Inhibitor	99.92%	Unkown
HY-112443	AZD3458	Inhibitor	99.82%	Unkown
HY-15672	FM19G11	Inhibitor	98.35%	Unkown
HY-10115A	PI-103 Hydrochloride		98.00%	Unkown
HY-121222	alpha-Bisabolol		≥80.0%	Unkown
HY-17587	4-Methylbenzylidene camphor		99.87%	Unkown
HY-N0314	Pectolinarin		99.89%	Unkown
HY-12763	GNE-317	Inhibitor	99.14%	Unkown
HY-12869	AZD-8835	Inhibitor	98.63%	Unkown
HY-101667	LTURM34	Inhibitor	99.89%	Unkown
HY-124652	TBK1/IKKε-IN-4	Inhibitor	99.83%	Unkown
HY-13440	AMG 511	Inhibitor	99.38%	Unkown
HY-P4322	H-Ile-Lys-Val-Ala-Val-OH	Activator	99.12%	Unkown
HY-15294	CZC24832	Inhibitor	99.35%	Unkown
HY-N5112B	β,β-Dimethylacrylshikonin		99.64%	Unkown
HY-15643A	LY 303511 hydrochloride		98.87%	Unkown
HY-17044A	Duvelisib (R enantiomer)	Inhibitor	/	Unkown
HY-107364	MTX-211	Inhibitor	≥98.0%	Unkown
HY-112897	IITZ-01		99.05%	Unkown
HY-111570	AZ2	Inhibitor	99.38%	Unkown
HY-19962	Paxalisib		99.74%	Yes
HY-101146	SF2523	Inhibitor	98.25%	Unkown
HY-110109	ETP-45658	Inhibitor	98.05%	Unkown
HY-120213	YH-306		98.01%	Unkown
HY-156406	PITCOIN4	Inhibitor	99.97%	Unkown
HY-N0479	Licarin B	Activator	99.93%	Unkown
HY-N6017	Bakkenolide A	Inhibitor	99.87%	Unkown
HY-100470	NSC781406	Inhibitor	99.97%	Unkown
HY-112613	UCB9608	Inhibitor	99.43%	Unkown
HY-131972	PF-06843195	Inhibitor	99.06%	Unkown
HY-13530	CAY10505		99.75%	Unkown
HY-100385	Brevianamide F	Inhibitor	99.30%	Unkown
HY-13514	TG 100713	Inhibitor	99.49%	Unkown
HY-139534	ARI-1		99.76%	Unkown
HY-143403	PI3K-IN-31	Inhibitor	99.55%	Unkown
HY-135827	Roginolisib	Inhibitor	99.89%	Unkown
HY-13531	AS-604850	Inhibitor	99.95%	Unkown
HY-15271	WYE-687	Inhibitor	98.05%	Unkown
HY-153894	SRX3177	Inhibitor	99.59%	Unkown
HY-N2112	Glaucocalyxin A		99.39%	Unkown
HY-N3354	Lupiwighteone	Inducer	98.63%	Unkown
HY-N6896	Isoviolanthin	Inhibitor	99.66%	Unkown
HY-111508	PI3K/mTOR Inhibitor-2	Inhibitor	98.25%	Unkown
HY-115870	AZD8154	Inhibitor	99.69%	Unkown
HY-136198	SRX3207	Inhibitor	98.50%	Unkown
HY-136268	AQX-435	Activator	99.19%	Unkown
HY-108606	PI-828	Inhibitor	99.09%	Unkown
HY-110193	SPP-86	Inhibitor	99.62%	Unkown
HY-11080	PKI-179	Inhibitor	≥98.0%	Unkown
HY-128333	PI3K/mTOR Inhibitor-4	Inhibitor	97.00%	Unkown
HY-147768	PI3K/AKT-IN-2		98.10%	Unkown
HY-150618	PI3Kα-IN-9		99.17%	Unkown
HY-19763	BEBT-908	Inhibitor	99.14%	Unkown
HY-N2491	Deoxyelephantopin	Inhibitor	99.97%	Unkown
HY-N6064	Polygalacin D		99.95%	Unkown
HY-N6263	EGCG Octaacetate	Inhibitor	99.90%	Unkown
HY-10811	GNE-493	Inhibitor	98.33%	Unkown
HY-11042	GNE-477	Inhibitor	98.70%	Unkown
HY-13333	NVP-BAG956	Inhibitor	99.12%	Unkown
HY-100603	GSK-F1		95.00%	Unkown
HY-101921	PI3Kδ-IN-1	Inhibitor	99.60%	Unkown
HY-100398	PF-04979064	Inhibitor	99.83%	Unkown
HY-106012	PI4K-IN-1	Inhibitor	/	Unkown
HY-123952	RTC-5	Inhibitor	99.89%	Unkown
HY-19312S	3-Methyladenine-d3		99.44%	Unkown
HY-N0103A	Sophocarpine monohydrate		99.91%	Unkown
HY-N0392	Polygalasaponin F	Inhibitor	99.74%	Unkown
HY-N5072	Desmethylglycitein	Inhibitor	98.98%	Unkown
HY-N6843	Arnicolide D		99.20%	Unkown
HY-N6950	Hederacolchiside A1		99.69%	Unkown
HY-118717	mTOR inhibitor WYE-28	Inhibitor	99.75%	Unkown
HY-16122B	CAL-130 Hydrochloride	Inhibitor	98.74%	Unkown
HY-135827A	Roginolisib hemifumarate	Inhibitor	99.95%	Unkown
HY-111510	IPI-3063	Inhibitor	99.22%	Unkown
HY-131345A	(S)-PI3Kα-IN-4	Inhibitor	99.79%	Unkown
HY-147419	Vulolisib	Inhibitor	99.60%	Unkown
HY-11080A	PKI-179 hydrochloride	Inhibitor	98.11%	Unkown
HY-112172	Tenalisib R Enantiomer		98.0%	Unkown
HY-115620	AQX-016A		98.00%	Unkown
HY-13504	PIK-293	Inhibitor	99.41%	Unkown
HY-136512	Streptazolin		98.65%	Unkown
HY-13864	PF-4989216		99.69%	Unkown
HY-153120A	PI3K/mTOR Inhibitor-13 sodium	Inhibitor	98.13%	Unkown
HY-19341	Compound 401	Inhibitor	99.09%	Unkown
HY-N3127	Orobol	Inhibitor	99.28%	Unkown
HY-N3260	Methyllucidone		≥98.0%	Unkown
HY-10812	GNE-490	Inhibitor	96.29%	Unkown
HY-N1967	Dihydrocurcumin		99.77%	Unkown
HY-18650	KU 59403	Inhibitor	99.23%	Unkown
HY-11105	Pilaralisib analogue		99.67%	Unkown
HY-111383	LX2343		99.80%	Unkown
HY-151622	PI3K/mTOR Inhibitor-11	Inhibitor	98.74%	Unkown
HY-124036	DS-7423	Inhibitor	99.75%	Unkown
HY-131345	PI3Kα-IN-4	Inhibitor	99.83%	Unkown
HY-133124	PARP/PI3K-IN-1		99.43%	Unkown
HY-18085S1	Quercetin-d3		/	Unkown
HY-118521	AS-041164	Inhibitor	99.32%	Unkown
HY-120438	TASP0415914	Inhibitor	99.37%	Unkown
HY-12652	AZD3147	Inhibitor	99.93%	Unkown
HY-130307	Rubrofusarin	Inhibitor	98.19%	Unkown
HY-133907	NVS-PI3-4	Inhibitor	99.74%	Unkown
HY-139412	Gilmelisib	Inhibitor	99.62%	Unkown
HY-143275	HL-8	Inhibitor	/	Unkown
HY-144993	PI3Kδ/γ-IN-1	Inhibitor	99.85%	Unkown
HY-150019	PI3K-IN-36	Inhibitor	98.76%	Unkown
HY-15271A	WYE-687 dihydrochloride	Inhibitor	≥98.0%	Unkown
HY-157169	IBL-302	Inhibitor	/	Unkown
HY-160093	SQLE-IN-1		98.82%	Unkown
HY-N0728S	α-Linolenic acid-d5	Inhibitor	/	Unkown
HY-N2051	Zeylenone	Activator	≥98.0%	Unkown
HY-N2590	Lupenone	Inhibitor	≥98.0%	Unkown
HY-N3035	Tetrahydroepiberberine	Inhibitor	99.20%	Unkown
HY-N4042	Hirsutenone	Inhibitor	≥96.0%	Unkown
HY-N7363	Isolongifolene	Inhibitor	≥98.0%	Unkown
HY-W005308	N-BOC-DL-serine methyl ester		≥97.0%	Unkown
HY-12340	ETP-46321	Inhibitor	99.65%	Unkown
HY-15477A	YS-49 monohydrate		99.56%	Unkown
HY-16355	NVP-QAV-572	Inhibitor	98.05%	Unkown
HY-103224	PIT-1	Inhibitor	/	Unkown
HY-12895	SKI V		98.09%	Unkown
HY-142646	PI3Kδ-IN-9	Inhibitor	/	Unkown
HY-144876	RIDR-PI-103	Inducer	98.02%	Unkown
HY-112602	PI3K/mTOR Inhibitor-1	Inhibitor	/	Unkown
HY-128582	PI3K/HDAC-IN-1	Inhibitor	/	Unkown
HY-132880	GSK251	Inhibitor	99.88%	Unkown
HY-151137	HSP90/mTOR-IN-1		/	Unkown
HY-101115	PI3K-IN-6	Inhibitor	/	Unkown
HY-101517	PI3K-IN-2	Inhibitor	/	Unkown
HY-112286	PI3Kγ inhibitor 2	Inhibitor	/	Unkown
HY-112439	PI3Kdelta inhibitor 1	Inhibitor	/	Unkown
HY-112608	CHMFL-PI3KD-317	Inhibitor	98.04%	Unkown
HY-112614	ATM Inhibitor-1	Inhibitor	/	Unkown
HY-131910	IHMT-PI3Kδ-372	Inhibitor	99.75%	Unkown
HY-132231	FD223		98.68%	Unkown
HY-132299	PI3Kγ inhibitor 4	Inhibitor	/	Unkown
HY-132807	Amdizalisib	Inhibitor	/	Unkown
HY-133029	PI3K-IN-9	Inhibitor	/	Unkown
HY-134472	PI3Kδ-IN-8	Inhibitor	/	Unkown
HY-10116	PI-540	Inhibitor	/	Unkown
HY-101776	Desmethyl-VS-5584	Inhibitor	/	Unkown
HY-103030	PI3K-IN-32	Inhibitor	/	Unkown
HY-105666	TGX-155	Inhibitor	/	Unkown
HY-10620	PI3K-IN-22	Inhibitor	/	Unkown
HY-108016	Peruvoside		/	Unkown
HY-109633	PI3K-IN-18	Inhibitor	/	Unkown
HY-111172	Inotilone	Inhibitor	/	Unkown
HY-111209	Pichromene	Inhibitor	/	Unkown
HY-112191	PI3K-IN-10	Inhibitor	/	Unkown
HY-114457	Phosphatidylinositol 4,5-bisphosphate		/	Unkown
HY-116431	I-BOP	Agonist	/	Unkown
HY-118712	mTOR inhibitor WYE-23	Inhibitor	/	Unkown
HY-121012	(rac)-AG-205		/	Unkown
HY-121246S	Fluorofenidone-d3		/	Unkown
HY-123849	SN32976	Inhibitor	/	Unkown
HY-124647	PI3Kα-IN-1	Inhibitor	/	Unkown
HY-125136	Chaetominine	Inhibitor	/	Unkown
HY-125376	PI3Kδ-IN-3	Inhibitor	/	Unkown
HY-125542	DCZ3301		/	Unkown
HY-126083	17β-Hydroxywortmannin	Inhibitor	/	Unkown
HY-128634	Anticancer agent 164		/	Unkown
HY-131015	HaXS8		98.69%	Unkown
HY-131055	Mytoxin B		/	Unkown
HY-131502	Taspine	Inhibitor	/	Unkown
HY-132898	PI3K-IN-23	Activator	/	Unkown
HY-136806	PI3K-IN-12	Inhibitor	/	Unkown
HY-139810	ETP-47037	Inhibitor	/	Unkown
HY-139832	MCX 28	Inhibitor	/	Unkown
HY-139880	PI3Kγ inhibitor 5	Inhibitor	/	Unkown
HY-141476	PI3K/mTOR Inhibitor-3	Inhibitor	/	Unkown
HY-14152	Prucalopride hydrochloride	Agonist	/	Unkown
HY-141690A	PI3K-IN-19 hydrochloride	Inhibitor	/	Unkown
HY-142676	PI3K-IN-26	Inhibitor	/	Unkown
HY-142677	PI3K-IN-27		/	Unkown
HY-143472	PI3Kδ-IN-11		/	Unkown
HY-144059	AKT-IN-9	Inhibitor	/	Unkown
HY-144060	AKT-IN-10	Inhibitor	/	Unkown
HY-144254	PI3Kδ-IN-10		/	Unkown
HY-144295	PI3Kα-IN-5	Inhibitor	/	Unkown
HY-144450	PI3K-IN-29	Inhibitor	/	Unkown
HY-144686	ATM Inhibitor-3	Inhibitor	/	Unkown
HY-144687	ATM Inhibitor-4	Inhibitor	/	Unkown
HY-144692	MEK/PI3K-IN-1	Inhibitor	/	Unkown
HY-144693	MEK/PI3K-IN-2	Inhibitor	/	Unkown
HY-145338	PI3Kβ-IN-1	Inhibitor	/	Unkown
HY-145358	FAP-PI3KI1	Inhibitor	/	Unkown
HY-145432	PI3K-IN-28	Inhibitor	/	Unkown
HY-146016	PI3K/mTOR Inhibitor-5	Inhibitor	/	Unkown
HY-146159	PI3K/HDAC-IN-2	Inhibitor	/	Unkown
HY-146200	PI3K/mTOR Inhibitor-8	Inhibitor	/	Unkown
HY-146260	NVP-CLR457	Inhibitor	/	Unkown
HY-146504	Topoisomerase I/II inhibitor 3		/	Unkown
HY-146743	Antitumor agent-53	Inducer	/	Unkown
HY-146789	PI3Kδ/γ-IN-2	Inhibitor	/	Unkown
HY-146835S	(Rac)-16:0PI(3,5)P2-d5 ammonium		/	Unkown
HY-147284	PI3K-IN-37	Inhibitor	/	Unkown
HY-147285	PI3K/mTOR Inhibitor-9	Inhibitor	/	Unkown
HY-147567	ATR-IN-15	Inhibitor	/	Unkown
HY-147613	PI3K/mTOR Inhibitor-6	Inhibitor	/	Unkown
HY-147614	PI3K/mTOR Inhibitor-7	Inhibitor	/	Unkown
HY-147767	PI3Kα-IN-6		/	Unkown
HY-147792	WNY1613	Inhibitor	/	Unkown
HY-147898	PI3K-IN-33		/	Unkown
HY-147899	PI3K-IN-34		/	Unkown
HY-147900	PI3K-IN-35		/	Unkown
HY-147911	COX-2/PI3K-IN-1	Inhibitor	/	Unkown
HY-147912	COX-2/PI3K-IN-2	Inhibitor	/	Unkown
HY-147913	PI3K/Akt/mTOR-IN-3		/	Unkown
HY-147966	HDAC-IN-43	Inhibitor	/	Unkown
HY-147983	PI3Kα-IN-8		/	Unkown
HY-148317	PI3Kγ inhibitor 6	Inhibitor	/	Unkown
HY-149000	PI3Kα-IN-7		/	Unkown
HY-149091	KDM5B-IN-4		/	Unkown
HY-149092	Anticancer agent 109		/	Unkown
HY-149205	CXJ-2	Inhibitor	/	Unkown
HY-149235	PI3Kδ-IN-12	Inhibitor	/	Unkown
HY-149427	PI3Kα-IN-12	Inhibitor	/	Unkown
HY-149472	Anti-osteoporosis agent-4	Inhibitor	/	Unkown
HY-149493	IHMT-PI3K-455	Inhibitor	/	Unkown
HY-149521	PI3K-IN-47	Inhibitor	/	Unkown
HY-149539	PLM-101	Inhibitor	/	Unkown
HY-149556	MTX-241F	Inhibitor	/	Unkown
HY-149634	PI3Kδ-IN-17	Inhibitor	/	Unkown
HY-149669	PH14	Inhibitor	98.23%	Unkown
HY-14971A	AKT inhibitor IV	Inhibitor	/	Unkown
HY-150034	PI3K-IN-38	Inhibitor	/	Unkown
HY-150061	NVP-BBD130	Inhibitor	/	Unkown
HY-150587	Anti-inflammatory agent 31	Inhibitor	/	Unkown
HY-150638	PI3Kδ/γ-IN-3		/	Unkown
HY-151635	PI3K/VEGFR2-IN-1		/	Unkown
HY-151915	ATR-IN-20	Inhibitor	/	Unkown
HY-152238	PI3K/mTOR Inhibitor-12	Inhibitor	/	Unkown
HY-15268	PP487	Inhibitor	/	Unkown
HY-152774	Antitumor agent-86	Inhibitor	/	Unkown
HY-15280	GSK2292767	Inhibitor	98.89%	Unkown
HY-153120	PI3K/mTOR Inhibitor-13	Inhibitor	/	Unkown
HY-153703	PI3Kγ inhibitor 7	Inhibitor	/	Unkown
HY-153915	PI3Kα-IN-11	Inhibitor	95.35%	Unkown
HY-155066	FD274	Inhibitor	/	Unkown
HY-155124	Antiproliferative agent-32	Inducer	/	Unkown
HY-155180	FD2056	Inhibitor	/	Unkown
HY-155232	PI3Kδ-IN-16		/	Unkown
HY-155520	Antileishmanial agent-19	Inhibitor	/	Unkown
HY-155570	Anticancer agent 137		/	Unkown
HY-155730	PI3K-IN-41	Inhibitor	/	Unkown
HY-155833	PI3Kδ-IN-13	Inhibitor	/	Unkown
HY-155975	PI3Kδ-IN-14	Inhibitor	/	Unkown
HY-155996	FD2157		/	Unkown
HY-156018	PI3Kα-IN-13	Inhibitor	/	Unkown
HY-156080	PI3K-IN-48	Inhibitor	/	Unkown
HY-156091	PI3Kα/HDAC6-IN-1	Inhibitor	/	Unkown
HY-156445	PI3K/mTOR Inhibitor-14	Inhibitor	/	Unkown
HY-157125	PI3Kα-IN-14		/	Unkown
HY-157128	PI3Kδ-IN-18	Inhibitor	/	Unkown
HY-157287	(S)-Phe-A110/B319		/	Unkown
HY-157288	(R)-Phe-A110/B319		/	Unkown
HY-157295	PI3K/HDAC-IN-3	Inhibitor	/	Unkown
HY-157319	PI3Kα-IN-15	Inhibitor	/	Unkown
HY-158017	WXM-1-170		/	Unkown
HY-158050	PXB17	Inhibitor	/	Unkown
HY-160282	PI3K-IN-49	Inhibitor	/	Unkown
HY-160283	PI3K-IN-50	Inhibitor	/	Unkown
HY-160418	PI3K-IN-51	Inhibitor	/	Unkown
HY-161140	PI3Kα-IN-16	Inhibitor	/	Unkown
HY-161144	AKT-IN-21		/	Unkown
HY-161301	PI3K-IN-52	Inhibitor	/	Unkown
HY-161362	SR-3-65		/	Unkown
HY-161366	OMS14	Inhibitor	/	Unkown
HY-161373	PI3Kα-IN-22	Inhibitor	/	Unkown
HY-162268	MALT1-IN-13		/	Unkown
HY-162292	Anticancer agent 190	Inhibitor	/	Unkown
HY-162382	KTC1101	Inhibitor	/	Unkown
HY-163151	JE-133	Inhibitor	/	Unkown
HY-163360	PI3Kα-IN-19	Inhibitor	/	Unkown
HY-163361	PI3Kα-IN-20	Inhibitor	/	Unkown
HY-17508S1	Clarithromycin-d3		/	Unkown
HY-18085A	Quercetin hydrate		/	Unkown
HY-18085S	Quercetin-d5		/	Unkown
HY-18085S2	Quercetin-13C3		/	Unkown
HY-48869	PI3K-IN-46		≥98.0%	Unkown
HY-B0965AS	Thioridazine-d3 hydrochloride		99.19%	Unkown
HY-N0361S	Dihydrocapsaicin-d3		/	Unkown
HY-N0451R	Acacetin (Standard)	Inducer	/	Unkown
HY-N0728R	α-Linolenic acid (Standard)	Inhibitor	/	Unkown
HY-N0728S2	α-Linolenic acid-d14	Inhibitor	/	Unkown
HY-N0728S3	α-Linolenic acid-13C18	Inhibitor	/	Unkown
HY-N0776R	Isorhamnetin (Standard)	Inhibitor	/	Unkown
HY-N10106	Dihydromyristicin	Inhibitor	/	Unkown
HY-N10802	6-O-Isobutyrylbritannilactone	Inhibitor	/	Unkown
HY-N12044	Asparanin A	Inducer	/	Unkown
HY-N1338	Royleanone	Inhibitor	/	Unkown
HY-N2602	Sanggenol L	Inhibitor	/	Unkown
HY-N3542	Carpachromene	Inhibitor	/	Unkown
HY-N3720	Demethoxycapillarisin	Inhibitor	/	Unkown
HY-N5136	25(R,S)-Ruscogenin	Inhibitor	99.84%	Unkown
HY-N8884	Coelonin	Inhibitor	/	Unkown
HY-N8931	Monomethyl lithospermate	Activator	/	Unkown
HY-P0175A	740 Y-P TFA		/	Unkown
HY-P10090	Apoptin-derived peptide		/	Unkown
HY-P10093	Penetratin-PI3Kγ(126-150)	Inhibitor	/	Unkown
HY-P4790	Acetyl-Exenatide	Inhibitor	/	Unkown
HY-RS10463	PI3 Human Pre-designed siRNA Set A		/	Unkown
HY-W040417	Boc-L-cyclobutylglycine		98.91%	Unkown
HY-10549	PI3Kγ inhibitor 1	Inhibitor	/	Unkown
HY-108418	PI3Kδ-IN-15	Inhibitor	/	Unkown
HY-12338	ON 146040	Inhibitor	95.05%	Unkown
HY-12517	GNE-293	Inhibitor	/	Unkown
HY-126049	(S)-Oxiracetam	Inhibitor	98.78%	Unkown
HY-132276	PtdIns-(3,4,5)-P3-biotin sodium		/	Unkown
HY-15288	PI3kδ inhibitor 1	Inhibitor	/	Unkown
HY-155211	mTOR inhibitor-13	Inhibitor	/	Unkown
HY-156371	MIPS-21335	Inhibitor	/	Unkown
HY-15643	LY 303511		/	Unkown
HY-160458	PI3Kα-IN-17	Inhibitor	/	Unkown
HY-16122	CAL-130 Racemate	Inhibitor	/	Unkown
HY-16122A	CAL-130	Inhibitor	/	Unkown
HY-N8380	(-)-Latifolin		/	Unkown
HY-122593	PI3Kδ-IN-5	Inhibitor	99.62%	Unkown
HY-18310	NIBR-17	Inhibitor	/	Unkown
HY-10108A	LY294002 hydrochloride		/	Unkown
HY-101114	LAS191954		/	Unkown
HY-12279F	Umbralisib R-enantiomer		99.52%	Unkown
HY-N1904	4′-Hydroxywogonin		/	Unkown
HY-U00326	PI3Kα/mTOR-IN-1	Inhibitor	/	Unkown

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