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" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (2) 17β-HSD (3) 5-HT Receptor (44) AAK1 (3) ACSL Family (2) Acyltransferase (7) ADC Antibody (1) ADC Linker (2) ADC Payload (6) Adenosine Receptor (11) Adenylate Cyclase (3) Adrenergic Receptor (35) Akt (34) Aldehyde Dehydrogenase (ALDH) (1) Aldose Reductase (5) Amine N-methyltransferase (2) Amino Acid Derivatives (3) Amino acid Transporter (1) Aminoacyl-tRNA Synthetase (1) Aminopeptidase (1) AMPK (11) Amylases (9) Amylin Receptor (1) Amyloid-β (14) Anaplastic lymphoma kinase (ALK) (8) Androgen Receptor (4) Angiotensin Receptor (5) Angiotensin-converting Enzyme (ACE) (1) Annexin A (1) Antibiotic (38) Antibody-Drug Conjugates (ADCs) (3) APC (1) Apelin Receptor (APJ) (2) Apolipoprotein (2) Apoptosis (260) Arenavirus (4) Arp2/3 Complex (2) Arrestin (1) Aryl Hydrocarbon Receptor (6) ASCT (1) ATM/ATR (2) Aurora Kinase (17) Autophagy (90) Bacterial (162) Bcl-2 Family (23) Bcr-Abl (11) BCRP (1) Beta-lactamase (5) Beta-secretase (7) Biochemical Assay Reagents (363) BMI1 (1) 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Adenosyltransferase (MAT) (3) METTL3 (9) mGluR (10) MHC (3) MicroRNA (1) Microtubule/Tubulin (29) Mitochondrial Metabolism (11) Mitophagy (8) Mitosis (4) Mixed Lineage Kinase (1) MMP (34) MOFs (240) Molecular Glues (13) Monoamine Oxidase (17) Monocarboxylate Transporter (2) Motilin Receptor (1) Mps1 (1) mRNA (4) mTOR (25) MyD88 (1) Myosin (4) Na+/H+ Exchanger (NHE) (8) Na+/HCO3- Cotransporter (1) Na+/K+ ATPase (1) nAChR (5) NADPH Oxidase (7) NAMPT (1) Necroptosis (4) NEKs (1) Neurokinin Receptor (5) Neuropeptide Y Receptor (4) Neurotensin Receptor (1) NF-κB (45) NO Synthase (21) NOD-like Receptor (NLR) (16) Notch (6) NTPDase (1) Nuclear Factor of activated T Cells (NFAT) (2) Nuclear Hormone Receptor 4A/NR4A (3) Nucleoside Antimetabolite/Analog (19) Opioid Receptor (14) Orexin Receptor (OX Receptor) (3) Organoid (1) Orphan GPCR (1) Orthopoxvirus (4) Oxidative Phosphorylation (1) P-glycoprotein (6) P2X Receptor (3) P2Y Receptor (41) p38 MAPK (44) p97 (1) PAK (5) Paraptosis (1) Parasite (62) PARP (44) PCSK9 (2) PD-1/PD-L1 (19) PDGFR (16) PDHK (1) PDI (3) PDK-1 (1) Penicillin-binding protein (PBP) (1) PERK (5) PGE synthase (3) Phosphatase (16) Phosphodiesterase (PDE) (26) Phospholipase (4) Phosphomannose Isomerase (PMI) (1) Phosphoramidites (4) Photosensitizer (1) Phytohormone (2) PI3K (40) PI4K (1) Pim (4) PIN1 (2) PINK1/Parkin (1) PKA (8) PKC (18) Polo-like Kinase (PLK) (6) Poly(ADP-ribose) Glycohydrolase (PARG) (1) Potassium Channel (40) PPAR (21) Prion Protein (1) Prostaglandin Receptor (28) PROTAC Linkers (73) PROTACs (70) Protease Activated Receptor (PAR) (5) Proteasome (3) Proteasome Cap Targeting Chimeras (1) Protein Arginine Deiminase (5) Proton Pump (2) Protoporphyrinogen IX oxidase (3) PTEN (1) Pyk2 (1) Pyroptosis (2) Quinone Reductase (1) RAD51 (1) Radionuclide-Drug Conjugates (RDCs) (3) Raf (13) RAR/RXR (9) Ras (21) Reactive Oxygen Species (ROS) (53) Reference Standards (232) Renin (2) RET (14) Reverse Transcriptase (6) RGS Protein (1) RIO Kinase (2) RIP kinase (5) ROCK (9) ROR (10) ROS Kinase (4) RSV (8) RUNX (1) Salt-inducible Kinase (SIK) (5) SARS-CoV (73) Separase (1) Ser/Thr Kinase (1) Ser/Thr Protease (7) Serotonin Transporter (12) SGK (3) SGLT (5) SHP1 (1) SHP2 (8) Sigma Receptor (4) Sirtuin (6) Small Interfering RNA (siRNA) (205) Smo (1) SNIPERs (1) SOD (3) Sodium Channel (45) Somatostatin Receptor (18) SOS1 (4) SphK (1) Src (15) STAT (22) Stearoyl-CoA Desaturase (SCD) (1) Steroid Sulfatase (1) STING (6) STK33 (2) Succinate Dehydrogenase (6) Survivin (1) SWI/SNF Complex (2) Syk (5) TAM Receptor (10) Target Protein Ligand-Linker Conjugates (4) Taste Receptor (3) Tau Protein (1) TGF-beta/Smad (4) TGF-β Receptor (13) Thrombin (3) Thyroid Hormone Receptor (3) Tie (2) TMPRSS6 (1) TMV (2) TNF Receptor (27) Toll-like Receptor (TLR) (19) Topoisomerase (13) Trace Amine-associated Receptor (TAAR) (1) Transferrin Receptor (1) Transmembrane Glycoprotein (5) Transthyretin (TTR) (1) Trk Receptor (10) TRP Channel (13) TSH Receptor (1) Tyrosinase (13) ULK (5) URAT1 (3) Urea Transporter (1) Urease (3) Urotensin Receptor (7) Vasopressin Receptor (7) VDAC (1) VEGFR (34) Virus Protease (4) VISTA (1) VSV (1) VZV (2) Wee1 (7) Wnt (7) Xanthine Oxidase (6) YAP (7) Zinc Finger Protein (1) α-synuclein (3) β-catenin (4) β-glucuronidase (2) γ-secretase (4)
By Research Areas:	Cancer (1259) Cardiovascular Disease (188) Endocrinology (83) Infection (489) Inflammation/Immunology (493) Metabolic Disease (469) Neurological Disease (504)
Click Chemistry:	ADC Synthesis (1) PROTAC Synthesis (7) Azide (10) Alkynes (13)
Oligonucleotides:	Adenosine (1) Chemokine & Receptors (1) Rat Pre-designed siRNA Sets (43) mRNA (3) Phospholipids (12) siRNA drugs (1) Other Phosphoramidite (4) Cholesterol (3) siRNAs (203) Pegylated Lipids (9) Nucleoside Analogs (7) Uridine (1) Emulsifiers (1) Mouse Pre-designed siRNA Sets (45) Cationic Lipids (15) Human Pre-designed siRNA Sets (114) Phosphoramidites (4)

4203

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

122

Biochemical Assay Reagents

184

Peptides

MCE Kits

Inhibitory Antibodies

394

Natural
Products

274

Recombinant Proteins

324

Isotope-Labeled Compounds

300

Antibodies

Click Chemistry

257

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113123

LysoPC(14:0/0:0) 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine	Endogenous Metabolite	Neurological Disease Metabolic Disease
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

HY-N1490

14-Deoxy-11,12-didehydroandrographolide 4 Publications Verification 14-dehydro Andrographolide; AP10	NF-κB	Inflammation/Immunology Cancer
14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation.

HY-113489

14,15-Epoxyeicosatrienoic acid 14,15-EET	Endogenous Metabolite	Cardiovascular Disease Neurological Disease
14,15-Epoxyeicosatrienoic acid (14,15-EET) is a metabolite of Arachidonic acid (HY-109590). 14,15-Epoxyeicosatrienoic acid is a potent inhibitor of in vivo platelet aggregation. 14,15-Epoxyeicosatrienoic acid facilitates astrocytic Aβ clearance. 14,15-Epoxyeicosatrienoic acid can be used for Alzheimer's Disease research .

HY-P3993A

(Gly14)-Humanin (human) acetate 14-Glycine-Humanin (human) acetate	Apoptosis	Neurological Disease
(Gly14)-Humanin (human) (14-Glycine-Humanin (human)) acetate is an analog of Humanin in which the 14th amino acid serine was replaced with glycine (Gly). (Gly14)-Humanin (human) acetate has anti-apoptotic and neuroprotective functions .

HY-N4323

14-Deoxyandrographolide 1 Publications Verification	Calcium Channel Apoptosis Caspase	Neurological Disease Metabolic Disease
14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A .

HY-177590

14-3-3-IN-2	MMP	Others
14-3-3-IN-2 is a 14-3-3 protein inhibitor with an IC₅₀ of 15 nM. 14-3-3-IN-2 can disrupt the interaction of 14-3-3α with aminopeptidase N and down-regulate 14-3-3α increased MMP-1 mRNA levels .

HY-130239A

(±)14-HDHA (±)14-HDoHE; 14-hydroxy Docosahexaenoic acid; (±)14-HDoHE	Drug Metabolite	Neurological Disease
(±)14-HDHA is the isomer of 14(S)-HDHA (HY-130239). 14(S)-HDHA is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway .

HY-130239

14(S)-HDHA 14(S)-HDoHE	Drug Metabolite	Neurological Disease
14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway .

HY-162404

(14S,15R)-14-Deoxyoxacyclododecindione	STAT TGF-beta/Smad Interleukin Related TGF-β Receptor	Inflammation/Immunology
(14S,15R)-14-Deoxyoxacyclododecindione (Compound 3) acts as an inhibitor of TGF-β-dependent Smad2/3 and IL-4-dependent STAT6, with IC₅₀ values of 90 nM and 20 nM, respectively. (14S,15R)-14-deoxyoxacyclododecindione is a potent IL-4 inhibitor with an IC₅₀ value of 20 nM. (14S,15R)-14-Deoxyoxacyclododecindione is applicable to the research of chronic inflammation and fibrotic diseases .

HY-P3993

(Gly14)-Humanin (human) 14-Glycine-Humanin (human)	Apoptosis	Neurological Disease
(Gly14)-Humanin (human) (14-Glycine-Humanin (human)) is an analog of Humanin in which the 14th amino acid serine was replaced with glycine (Gly). (Gly14)-Humanin (human) has anti-apoptotic and neuroprotective functions .

HY-N3505

14-Hydroxy sprengerinin C	Others	Others
14-Hydroxy sprengerinin C is a steroidal compound found in Ophiopogon japonicus.

HY-120954

14,15-EE-5(Z)-E 1 Publications Verification	Endogenous Metabolite	Cardiovascular Disease
14,15-EE-5(Z)-E is a structural analogue of 14, 15-epoxide dicartrienoic acid (14,15-EET). 14,15-EE-5(Z)-E antagonizes the relaxation of vascular smooth muscle induced by EET .

HY-133101

14-Norpseurotin	Endogenous Metabolite	Cancer
14-Norpseurotin is a compound isolated from the culture of Aspergillus fumigatus. 14-Norpseurotin significantly induces neurite outgrowth of rat pheochromocytoma cells (PC12) at a 10.0 microM concentration .

HY-W108232

14-Hydroxytetradecanoic acid	PROTAC Linkers	Cancer
14-Hydroxytetradecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-N11132

14-Episinomenine	Others	Others
14-Episinomenine is an alkaloid that can be isolated from Stephania cepharantha .

HY-N16392

14-epi-Berkeleylactone F	Endogenous Metabolite	Infection
14-epi-Berkeleylactone F (Compound 8) is a C-14 epimer of Berkeleylactone F (HY-N8386). 14-epi-Berkeleylactone F can be isolated from Penicillium turbatum NRRL 5630. 14-epi-Berkeleylactone F has no significant biological activity against bacterium (Staphylococcus aureus, Bacillus subtilis and E. coli), fungi Candida albicans, the parasite Giardia duodenalis and NS-1 murine myeloma cells .

HY-139261

1-Deoxysphingosine (m18:1(14Z)) 1-Deoxyso; 14Z-1-Deoxysphingosine (d18:1)	Biochemical Assay Reagents	Metabolic Disease
1-Deoxysphingosine (m18:1(14Z)) (1-Deoxyso; 14Z-1-Deoxysphingosine (d18:1)) is an ester product.

HY-168798

14:1 Cardiolipin sodium	Others	Metabolic Disease
14:1 Cardiolipin sodium is an anionic phospholipid containing the monounsaturated fatty acid Myristoleic acid (HY-113332).

HY-N4323R

14-Deoxyandrographolide (Standard)	Reference Standards Calcium Channel Apoptosis Caspase	Neurological Disease Metabolic Disease
14-Deoxyandrographolide (Standard) is the analytical standard of 14-Deoxyandrographolide. 14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A .

HY-N15997

14:0-14:0(COOH) PC DMPC-COOH	Biochemical Assay Reagents	Others
14:0-14:0(COOH) PC is a lipid for supported monolayer.

HY-W092216

14-Mercaptotetradecanoic acid	PROTAC Linkers	Cancer
14-Mercaptotetradecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-N16304

14:0 Dihydro SM (d18:0/14:0)	Biochemical Assay Reagents	Others
14:0 Dihydro SM (d18:0/14:0) is a sphingomyelin.

HY-124279

14-Pentadecenoic acid	Biochemical Assay Reagents	Others
14-Pentadecenoic acid is a 15-carbon long-chain fatty acid that contains an olefin functional group on the terminal carbon of its fatty tail. 14-Pentadecenoic acid can be used as a fibrous scaffold biomaterial for tissue engineering applications, as well as a metal-forming side-chain polymer for constructing capillary columns in gas chromatography .

HY-W033978

14-Bromotetradecan-1-ol	PROTAC Linkers	Cancer
14-Bromotetradecan-1-ol is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-146895S

14:0 Lyso PC-d27	Isotope-Labeled Compounds	Others
14:0 Lyso PC-d₂₇ is deuterium labeled 14:0 Lyso PC.

HY-115356

Eoxin E4 14,15-LTE4; EoxE4	Drug Metabolite	Cardiovascular Disease
Eoxin E4 (14,15-LTE₄) is the metabolite of 14,15-LTC₄ and 14,15-LTD₄. Eoxin E4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency than LTC₄, but approximately 100-fold greater potency than histamine .

HY-N8594

∆14-Vincamenine 14,15-Didehydrovincamenine	Drug Derivative	Others
∆14-Vincamenine (14,15-Didehydrovincamenine) is a natural alkaloid compound .

HY-CE00874

14-Methylheptadecanoyl-CoA 14-Methylheptadecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
14-Methylheptadecanoyl-CoA (14-Methylheptadecanoyl-coenzyme A) is a coenzyme A derivative.

HY-CE00878

14-Methyltetracosanoyl-CoA 14-Methyltetracosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
14-Methyltetracosanoyl-CoA (14-Methyltetracosanoyl-coenzyme A) is a coenzyme A derivative.

HY-CE00875

14-Methylicosanoyl-CoA 14-Methylicosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
14-Methylicosanoyl-CoA (14-Methylicosanoyl-coenzyme A) is a coenzyme A derivative.

HY-146880S

14:0-14:0 PC-d27	Isotope-Labeled Compounds	Others
14:0-14:0 PC-d₂₇ is deuterium labeled 14:0-14:0 PC.

HY-130239S

14(S)-HDHA-d5 14(S)-HDoHE-d₅	Isotope-Labeled Compounds Drug Metabolite	Neurological Disease
14(S)-HDHA-d₅ (14(S)-HDoHE-d₅) is deuterium labeled 14(S)-HDHA. 14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway .

HY-N9456

14-Anhydrodigitoxigenin	Na+/K+ ATPase	Others
14-Anhydrodigitoxigenin is a cardenolides that can be isolated from the leaves of Acokanthera oblongifolia. 14-Anhydrodigitoxigenin is a Na ⁺/K ⁺-ATPase inhibitor .

HY-146912S

14:0-16:1-14:0 TG-d5	Isotope-Labeled Compounds	Others
14:0-16:1-14:0 TG-d₅ is deuterium labeled 14:0-16:1-14:0 TG.

HY-105058A

14α/β-Vindeburnol 14α/β-RU 24722	Drug Derivative	Neurological Disease
14α/β-Vindeburnol (14α/β-RU 24722) a synthetic molecule derived from the eburnamine-vincamine alkaloid group, has many neuropsychopharmacological and antidepressant-like effects .

HY-N1494

(+)-14-Deoxy-ε-caesalpin 14-Deoxy-ε-caesalpin	NO Synthase	Inflammation/Immunology
(+)-14-Deoxy-ε-caesalpin (14-Deoxy-ε-caesalpin), a cassane diterpenoid, inhibits nitric oxide (NO) production release of RAW 264.7 cells stimulated by Lipopolysaccharide (LPS) .

HY-N1048

14-Benzoylneoline	Others	Others
14-Benzoylneoline is found in Aconitum subcuneatum .

HY-N0191A

14-epi-Andrographolide 14-Epiandrographolide	Others	Infection
14-epi-andrographolide is a diterpene analog of Andrographolide (HY-N0191), which is an NF-κB inhibitor and antiviral agent .

HY-W129735

14-((2,5-Dioxopyrrolidin-1-yl)oxy)-14-oxotetradecanoic acid	PROTAC Linkers	Cancer
14-((2,5-Dioxopyrrolidin-1-yl)oxy)-14-oxotetradecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W036523

14-Bromotetradecanoic acid	PROTAC Linkers	Cancer
14-Bromotetradecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-164357

14-Deoxypoststerone	Drug Derivative	Metabolic Disease
14-Deoxypoststerone is a steroid compound, a derivative of a steroid hormone .

HY-N1490R

14-Deoxy-11,12-didehydroandrographolide (Standard) 14-dehydro Andrographolide (Standard); AP10 (Standard)	Reference Standards NF-κB	Inflammation/Immunology Cancer
14-Deoxy-11,12-didehydroandrographolide (Standard) is the analytical standard of 14-Deoxy-11,12-didehydroandrographolide. This product is intended for research and analytical applications. 14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation.

HY-165952

14(Z)-Tricosenyl acetate	Biochemical Assay Reagents	Metabolic Disease
14(Z)-Tricosenyl acetate is an ester product.

HY-165945

14(Z)-Etherolenic acid	Biochemical Assay Reagents	Metabolic Disease
14(Z)-Etherolenic acid is an ester product.

HY-165951

14(Z)-Tricosenoyl chloride	Biochemical Assay Reagents	Metabolic Disease
14(Z)-Tricosenoyl chloride is an ester product.

HY-165947

14(Z)-Tricosenol	Biochemical Assay Reagents	Metabolic Disease
14(Z)-?Tricosenol is an ester product.

HY-121940

14-Methylhexadecanoic acid	Endogenous Metabolite	Others
14-Methylhexadecanoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-144015

14:1 EPC trifluoromethanesulfonate	Liposome	Others
14:1 EPC trifluoromethanesulfonate is ethyl-phosphatidylcholine (EPC) with monounsaturated 14:1 chains. 14:1 EPC trifluoromethanesulfonate shows transfection activity. 14:1 EPC trifluoromethanesulfonate can be used for drug delivery .

HY-N1488

14-Deoxy-17-hydroxyandrographolide 14-Deoxy-17β-hydroxyandrographolide	Drug Derivative	Others
14-Deoxy-17-hydroxyandrographolide is an ent-labdane diterpenoid compound isolated from the aerial parts of Andrographis paniculate .

HY-147777

14α-Demethylase/DNA Gyrase-IN-2	Bacterial DNA/RNA Synthesis	Infection
14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of *14α-Demethylase/DNA* Gyrase. 14α-Demethylase/DNA Gyrase-IN-2 has antimicrobial activities .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113123

LysoPC(14:0/0:0) 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine	Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

HY-N2468

Xylobiose 1,4-β-D-Xylobiose; 1,4-D-Xylobiose	Zea mays L. Polysaccharides Classification of Application Fields Gramineae Other Diseases Plants Disease Research Fields Saccharides Source Classification	TNF Receptor Claudin HSP
Xylobiose (1,4-β-D-Xylobiose; 1,4-D-Xylobiose) is an orally active Claudin 2/CLDN2 inhibitor and HSP27 inducer. Xylobiose works by regulating intestinal barrier function and glucose and lipid metabolism-related signaling pathways. Xylobiose inhibits CLDN2 expression to reduce intestinal permeability, induces HSP27 to enhance cell protection, and regulates the miR-122a/miR-33a axis to inhibit liver lipid synthesis and improve insulin resistance. Xylobiose can strengthen intestinal barrier integrity, reduce blood sugar and blood lipid levels, and reduce oxidative stress and inflammatory response. Xylobiose can be used in the study of type 2 diabetes and metabolic syndrome .

HY-N1490

14-Deoxy-11,12-didehydroandrographolide 4 Publications Verification 14-dehydro Andrographolide; AP10	Acanthaceae Classification of Application Fields Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Disease Research Fields Source Classification Cancer	NF-κB
14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation.

HY-N6839

1,4-b-D-Xylopentaose	Structural Classification Zea mays L. Polysaccharides Classification of Application Fields Gramineae Other Diseases Plants Disease Research Fields Saccharides Source Classification	Glycosidase
1,4-b-D-Xylopentaose is a linear pentasaccharide composed of 5 β-D-xylose units linked via 1,4-glycosidic bonds, and serves as a specific substrate for barley α-L-arabinofuranosidase .

HY-W004661

1,4-Dioxane-2,5-diol Hydroxy Acetaldehyde	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
1,4-Dioxane-2,5-diol is an endogenous metabolite.

HY-N7117

1,4-Cineole	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Ericaceae Plants Rhododendron anthopogonoides Maxim. Inflammation/Immunology Disease Research Fields Cancer	Environmental Pollutants TRP Channel
1,4-Cineole is an oxygenated monoterpene found in eucalyptus oil. 1,4-Cineole is a hTRPM8 and hTRPA1 agonist. 1,4-Cineole can increase intracellular Ca ²⁺ concentration. 1,4-Cineole exhibits anti-anxiety and anti-depression effects. 1,4-Cineole can be used for the research of neurological disease, such as depression .

HY-W015780

1,4-Dimethoxybenzene	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite
1,4-Dimethoxybenzene is an endogenous metabolite. 1,4-Dimethoxybenzene has an anti-anxiety effect, increasing atherogenic index (AI) levels in rabbits and inducing sedentary behavior. Sedentary behavior may increase blood cholesterol levels and disrupt blood lipids . 1,4-Dimethoxybenzene considers to be not clastogenic in the in vivo micronucleus test .

HY-N4323

14-Deoxyandrographolide 1 Publications Verification	Structural Classification Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Source Classification	Calcium Channel Apoptosis Caspase
14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A .

HY-N0358

1,4-Dicaffeoylquinic acid 1 Publications Verification 1,4-DCQA	Caprifoliaceae Classification of Application Fields Lonicera japonica Thunb. Other Phenylpropanoids Phenols Polyphenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields Source Classification	TNF Receptor Xanthine Oxidase
1,4-Dicaffeoylquinic acid (1,4-DCQA) is a phenylpropanoid compound that can be isolated from Xanthii fructus and an inhibitor of xanthine oxidase (IC₅₀: 7.36 μM). 1,4-Dicaffeoylquinic acid has anti-inflammatory activity and can inhibit the production of TNF-α induced by LPS (HY-D1056) .

HY-D0226

Quinizarin 1,4-Dihydroxyanthraquinone	Infection Quinones Structural Classification Classification of Application Fields Anthraquinones Phenols Polyphenols Solanaceae Plants Disease Research Fields Rhizophora mucronata Lam Source Classification	DNA/RNA Synthesis Fungal
Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (K_d=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth .

HY-150084

(±)14,15-Epoxyeicosatrienoic acid (±)14(15)-EET	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Cytochrome P450 Mitosis
(±)14,15-Epoxyeicosatrienoic acid ((±)14(15)-EET) is the Cytochrome P450 metabolite of arachidonic acid. While CYP3A4 may be involved in breast cancer cell growth, (±)14,15-Epoxyeicosatrienoic acid may promote mitosis and anchorage-dependent cloning through STAT3 affected by CYP3A4. (±)14,15-Epoxyeicosatrienoic acid exhibits STAT3-dependent cell growth promotion and may also participate in the autocrine/paracrine pathway that drives cell growth .

HY-N10472

STAT3-IN-14	Nicotiana tabacum L. Plants Solanaceae Naphthalene Quinones Source Classification	STAT
STAT3-IN-14 (Compound 1) is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 (Compound 1) can directly bind to the hinge region of STAT3 .

HY-108398B

11(Z),14(Z),17(Z)-Eicosatrienoic acid	Microorganisms Ketones, Aldehydes, Acids Source Classification	Endogenous Metabolite
11(Z),14(Z),17(Z)-Eicosatrienoic acid is an unsaturated fatty acid that can maintain the continued replication of functional mitochondria in Saccharomyces cerevisiae (KD115) .

HY-118840

1,4-D-Gulonolactone	Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Source Classification	Endogenous Metabolite
1,4-D-Gulonolactone is an endogenous metabolite.

HY-W014701

1,4-Dihydroxy-2-naphthoic acid	Ketones, Aldehydes, Acids Source Classification	Aryl Hydrocarbon Receptor Cytochrome P450 Apoptosis Interleukin Related
1,4-Dihydroxy-2-naphthoic acid is an aryl hydrocarbon receptor (AhR) agonist. 1,4-Dihydroxy-2-naphthoic acid is also a bacterially derived metabolite and has anti-inflammatory activity .

HY-N3505

14-Hydroxy sprengerinin C	Classification of Application Fields Dipsacaceae Other Diseases Dipsacus asper Wall. Plants Disease Research Fields Steroids Source Classification	Others
14-Hydroxy sprengerinin C is a steroidal compound found in Ophiopogon japonicus.

HY-W716889

2,6,10,14-Tetramethylhexadecane	Structural Classification Terpenoids Diterpenoids Plants Source Classification	Drug Derivative
2,6,10,14-Tetramethylhexadecane is an ester product.

HY-113208

13,14-Dihydro-15-keto Prostaglandin F2α 13,14-Dihydro-15-keto-PGF2α	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
13,14-Dihydro-15-keto Prostaglandin F2α (13,14-Dihydro-15-keto-PGF2α) is an endogenous metabolite present in Blood that can be used for the research of Pregnancy .

HY-N11274

T-MAS 4,4-Dimethylzymosterol; 14-Norlanosterol	Structural Classification Microorganisms Terpenoids Diterpenoids Source Classification	Endogenous Metabolite Drug Intermediate
T-MAS (4,4-Dimethylzymosterol) serves as an intermediate in cholesterol biosynthesis, stimulating oocytes for meiosis and modulating cumulus expansion .

HY-N11132

14-Episinomenine	Alkaloids Piperidine Alkaloids Stephania cepharantha Hayata Plants Menispermaceae Source Classification	Others
14-Episinomenine is an alkaloid that can be isolated from Stephania cepharantha .

HY-N16392

14-epi-Berkeleylactone F	Natural Products Microorganisms Source Classification	Endogenous Metabolite
14-epi-Berkeleylactone F (Compound 8) is a C-14 epimer of Berkeleylactone F (HY-N8386). 14-epi-Berkeleylactone F can be isolated from Penicillium turbatum NRRL 5630. 14-epi-Berkeleylactone F has no significant biological activity against bacterium (Staphylococcus aureus, Bacillus subtilis and E. coli), fungi Candida albicans, the parasite Giardia duodenalis and NS-1 murine myeloma cells .

HY-N11076

12E,14-Trien-19-oic acid	Cupressaceae Juniperus communis L. Terpenoids Diterpenoids Plants Source Classification	Others
12E,14-Trien-19-oic acid is a diterpenoid. 12E,14-Trien-19-oic acid can be isolated from Bhutanese medicinal plant, shug chher. 12E,14-Trien-19-oic acid can be used for the research of platelet aggregation .

HY-N8059

Fructo-oligosaccharide DP14	Structural Classification Polysaccharides Plants Compositae Saccharides Source Classification Erythrina sigmoidea Hua	Others
Fructo-oligosaccharide DP14 is an oligosaccharide that can be isolated from Atractylodes lancea .

HY-N9017

12E,14-Labdadien-20,8β-olide	Other Terpenoids Classification of Application Fields Terpenoids Labiatae Carpesium cernuum L. Other Diseases Plants Disease Research Fields Source Classification	Others
12E,14-Labdadien-20,8β-olide, a labdane diterpenoid, is a natural product that can be isolated from the rhizomes of Isodon yuennanensis .

HY-W142437

1,4-Dimethylnaphthalene	Structural Classification Natural Products Orchidaceae Plants Dendrobium devonianum Paxton Source Classification	Phytohormone
1,4-Dimethylnaphthalen is a non-competitive potato tuber sprouting inhibitor. 1,4-Dimethylnaphthalen blocks cell cycle progression (G1/S arrest) by inducing PP2A phosphatase and oxygen metabolism-related genes. 1,4-Dimethylnaphthalen is promising for research of fungistatic activity during potato storage and sprout control under abiotic stress .

HY-N4323R

14-Deoxyandrographolide (Standard)	Structural Classification Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Source Classification	Reference Standards Calcium Channel Apoptosis Caspase
14-Deoxyandrographolide (Standard) is the analytical standard of 14-Deoxyandrographolide. 14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A .

HY-N15997

14:0-14:0(COOH) PC DMPC-COOH	Lipid	Biochemical Assay Reagents
14:0-14:0(COOH) PC is a lipid for supported monolayer.

HY-N16304

14:0 Dihydro SM (d18:0/14:0)	Lipid	Biochemical Assay Reagents
14:0 Dihydro SM (d18:0/14:0) is a sphingomyelin.

HY-N15613

α-Synuclein inhibitor 14	Phenols Polyphenols Plants Tacca chantrieri Andre Taccaceae Source Classification	α-synuclein
α-Synuclein inhibitor 14 (Compound 3) is a diarylheptanoid that can be isolated from Alpinia officinarum. α-Synuclein inhibitor 14 can inhibit the aggregation of α-synuclein, with an inhibition rate of 72.4% at a concentration of 10 μM. α-Synuclein inhibitor 14 can be used in the research of neurodegenerative diseases such as Parkinson's disease .

HY-N15870

Apocholic Acid (Delta 14 isomer)	Lipid	Biochemical Assay Reagents
Apocholic Acid (Delta 14 isomer) is a cholic acid.

HY-N15967

Azido sphingosine (d14:1)	Lipid	Biochemical Assay Reagents
Azido sphingosine (d14:1) is a clickable sphingolipid that can be used in click chemistry reactions.

HY-W015780R

1,4-Dimethoxybenzene (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
1,4-Dimethoxybenzene (Standard) is the analytical standard of 1,4-Dimethoxybenzene. This product is intended for research and analytical applications. 1,4-Dimethoxybenzene is an endogenous metabolite.

HY-N2468R

Xylobiose (Standard) 1,4-β-D-Xylobiose (Standard); 1,4-D-Xylobiose (Standard)	Structural Classification Zea mays L. Polysaccharides Gramineae Plants Saccharides Source Classification	Reference Standards TNF Receptor Claudin HSP
Xylobiose (1,4-β-D-Xylobiose; 1,4-D-Xylobiose) is an orally active Claudin 2/CLDN2 inhibitor and HSP27 inducer. Xylobiose works by regulating intestinal barrier function and glucose and lipid metabolism-related signaling pathways. Xylobiose inhibits CLDN2 expression to reduce intestinal permeability, induces HSP27 to enhance cell protection, and regulates the miR-122a/miR-33a axis to inhibit liver lipid synthesis and improve insulin resistance. Xylobiose can strengthen intestinal barrier integrity, reduce blood sugar and blood lipid levels, and reduce oxidative stress and inflammatory response. Xylobiose can be used in the study of type 2 diabetes and metabolic syndrome .

HY-N9456

14-Anhydrodigitoxigenin	Apocynaceae Structural Classification Acokanthera oblongifolia (Hochst.) Codd Cardiacglycosides Plants Steroids Source Classification	Na+/K+ ATPase
14-Anhydrodigitoxigenin is a cardenolides that can be isolated from the leaves of Acokanthera oblongifolia. 14-Anhydrodigitoxigenin is a Na ⁺/K ⁺-ATPase inhibitor .

HY-N1048

14-Benzoylneoline	Alkaloids Classification of Application Fields Other Alkaloids Ranunculaceae Other Diseases Aconitum carmichaeli Debx. Plants Disease Research Fields Source Classification	Others
14-Benzoylneoline is found in Aconitum subcuneatum .

HY-N0191A

14-epi-Andrographolide 14-Epiandrographolide	Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Source Classification	Others
14-epi-andrographolide is a diterpene analog of Andrographolide (HY-N0191), which is an NF-κB inhibitor and antiviral agent .

HY-N1490R

14-Deoxy-11,12-didehydroandrographolide (Standard) 14-dehydro Andrographolide (Standard); AP10 (Standard)	Structural Classification Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Source Classification	Reference Standards NF-κB
14-Deoxy-11,12-didehydroandrographolide (Standard) is the analytical standard of 14-Deoxy-11,12-didehydroandrographolide. This product is intended for research and analytical applications. 14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation.

HY-N10507

Methyl 14-methylpentadecanoate	Structural Classification Azadirachta indica A. Juss. Plants Meliaceae Lipid	Biochemical Assay Reagents
Methyl 14-methylpentadecanoate is an ester product.

HY-N12027

AChE/BChE-IN-14	Alkaloids Fissistigma polyanthum (Hook. f. et Thoms.) Merr. Plants Annonaceae Isoquinoline Alkaloids Source Classification	Cholinesterase (ChE)
AChE/BChE-IN-14 (compound 13) is a benzylisoquinoline alkaloid isolated from the roots of Fissistigma polyanthum. AChE/BChE-IN-14 exhibits AChE and BChE inhibitions with antioxidant activities. AChE/BChE-IN-14 can be used for Alzheimer’s disease research .

HY-158623

(±)13(14)-DiHDPA (±)13,14-DiHDPE	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Drug Metabolite
(±)13(14)-DiHDPA ((±)13,14-DiHDPE) a metabolite of Docosahexaenoic acid (DHA; HY-B2167) by P450 (CYP) metabolic pathways .

HY-N15945

C14 Glucosyl(ß) ceramide (d18:1/14:0)	Lipid	Biochemical Assay Reagents
C14 Glucosyl(β) ceramide (d18:1/14:0) is a β-Glucosyl ceramide.

HY-N15006

14-O-Acetylindolactam V	Natural Products Microorganisms Source Classification	EBV
14-O-Acetylindolactam V can induce early Epstein-Barr virus antigen .

HY-N12879

(R)-10,14-Dimethylpentadecyl isobutyrate (R)-10Me 14Me-15:iBu	Natural Products Animals Source Classification	Others
(R)-10,14-Dimethylpentadecyl isobutyrate ((R)-10Me 14Me-15:iBu) is a female sex pheromone with insect electroantennographic (EGA) activity, isolated from tea tussock moth .

HY-123519

14α-Hydroxy Paspalinine	Infection Alkaloids Microorganisms Classification of Application Fields Disease Research Fields Indole Alkaloids Source Classification	Insecticide
14α-Hydroxy Paspalinine is a paspalinine derivative with antiinsectan activity from the sclerotia of Aspergillus nomius .

HY-N10162

14-Benzoyl-8-O-methylaconine	Alkaloids Terpenoids Other Alkaloids Ranunculaceae Diterpenoids Aconitum carmichaeli Debx. Plants Source Classification	Others
14-Benzoyl-8-O-methylaconine (compound 8) is an alkaloid from A. soongaricum var. pubescens .

HY-N10050

Coreoside B 14-Hydroxycoreoside A	Structural Classification Natural Products Cercis chinensis Bunge Plants Compositae Source Classification	Bacterial
Coreoside B (14-Hydroxycoreoside A) can be isolated from Coreopsis tinctoria Nutt. and has weak antibacterial activity .

HY-W717924

(Z)-14-Methyl-8-hexadecenal	Natural Products Rhizophora apiculata Blume Rhizophoraceae Plants Source Classification	Endogenous Metabolite
(Z)-14-Methyl-8-hexadecenal is a sex pheromone that can induce mating responses in male Trogoderma beetles, isolated from the spiracular exhalation distillates of female beetles .

HY-N15096

Milbemycin α14	Microorganisms Antibiotics Source Classification	Antibiotic Parasite
Milbemycin α14 is an antibiotic and has the effect of killing nematodes and mites .

HY-N15914

14:0 PE-DTPA pentaammonium	Lipid	Biochemical Assay Reagents
14:0 PE-DTPA pentaammonium, a phospholipid, is a chelator .

HY-N12529

13,14-EDT	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite
13,14-EDT is a metabolite of oxylipids and adrenal acid that is formed through the cytochrome P450 (CYP) pathway .

Cat. No.	Product Name	Chemical Structure

HY-78004S

1,2-Diphenylethane-d14
1,2-Diphenylethane-d₁₄ is the deuterium labeled 1,2-Diphenylethane .

HY-24385S

N-Nitrosodipropylamine-d14
N-Nitrosodipropylamine-d₁₄ is the deuterium labeled N-Nitrosodipropylamine[1].

HY-76025S

1,4-Dibromobenzene-d4
1,4-Dibromobenzene-d₄ is a deuterium labeled 1,4-Dibromobenzene. 1,4-Dibromobenzene is used as a fumigant and as a chemical intermediate for pharmaceuticals. Inhalation exposure gives rise to dizziness and chokingwhereas contact with skin or eye produces inflammation and burning in humans .

HY-N1132S

D-(+)-Trehalose-d14
D-(+)-Trehalose-d₁₄ is the deuterium labeled D-(+)-Trehalose. D-(+)-Trehalose, isolated from Saccharomyces cerevisiae, can be used as a food ingredient and pharmaceutical excipi .

HY-142786S

Di-o-tolyl-phosphate-d14
Di-o-tolyl-phosphate-d₁₄ is the deuterium labeled Di-o-tolyl-phosphate .

HY-B0704S

Azelaic acid-d14
Azelaic acid-d₁₄ is the deuterium labeled Azelaic acid . Azelaic acid is an organic compound produced by the ozonolysis of oleic acid;component of a number of hair and skin conditioners .

HY-B1779S3

Sucrose-d14
Sucrose-d₁₄ is the deuterium labeled Sucrose. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose can be applied in some animal models, including metabolic disease, obesity, diet on preferen

HY-W015490S

1,4-Naphthoquinone-d6

1,4-Naphthoquinone-d₆ is the deuterium labeled 1,4-Naphthoquinone. 1,4-Naphthoquinone is an inhibitor with broad-spectrum inhibitory activity targeting DNA polymerase, NF-κB and monoamine oxidase (MAO-A/B), with antibacterial and anti-biofilm efficacy. 1,4-Naphthoquinone is a competitive inhibitor of MAO-B (Ki=1.4 μM) and a non-competitive inhibitor of MAO-A (Ki=7.7 μM). 1,4-Naphthoquinone inhibits DNA polymerase pol α, β, γ, δ, ε, λ with IC₅₀ ranging from 5.57-128 μM. 1,4-Naphthoquinone inhibits tumor cell proliferation, induces apoptosis and necrosis, and has anti-angiogenic and anti-inflammatory activities by inducing oxidative stress, depleting glutathione (GSH), inhibiting DNA polymerase-mediated DNA synthesis and blocking NF-κB nuclear translocation. 1,4-Naphthoquinone can be used in anti-bacterial , anti-tumor and anti-inflammatory studies, including inhibition of melanoma and colon cancer cell growth and endothelial cell function, as well as LPS-induced inflammation models .

HY-B2176S4

ATP-d14 dilithium
ATP-d₁₄ (Adenosine 5'-triphosphate-d₁₄) dilithium is deuterium labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

HY-139961S

(±)14(15)-EET-d11
(±)14(15)-EET-d₁₁ is the deuterium labeled (±)14(15)-EET .

HY-W011873S

Palmitoleic acid-d14
Palmitoleic acid-d₁₄ is the deuterium labeled Palmitoleic acid. Palmitoleic acid, a composition of fatty acid, is implicated in the prevention of death from cerebrovascular disorders in SHRSP rats.

HY-113123S1

LysoPC(14:0/0:0)-d7
LysoPC(14:0/0:0)-d₇ (14:0 Lyso PC-d₇) is deuterium labeled LysoPC(14:0/0:0). LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

HY-150989S

1,4-Butanediol mononitrate-d8
1,4-Butanediol mononitrate-d₈ is the deuterium labeled 1,4-Butanediol mononitrate .

HY-N1150S10

Thymidine-d14
Thymidine-d₁₄ (DThyd-d₁₄; NSC 21548-d₁₄) is deuterium labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

HY-124177AS

C14 Ceramide (d18:1/14:0)-d7
C14 Ceramide (d18:1/14:0)-d₇ is the deuterium labeled C14 Ceramide (d18:1/14:0) (HY-124177A). C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research .

HY-150773S1

Guanosine triphosphate-d14 dilithium
Guanosine triphosphate-d₁₄ (GTP-d₁₄) dilithium is a deuterium labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19 .

HY-B1882S

Propazine-d14
Propazine-d₁₄ is the deuterium labeled Propazine .

HY-151580S

CDK2-IN-14-d3
CDK2-IN-14-d₃ is a potent and selective CDK2 inhibitor. CDK2-IN-14-d₃ can be used in research of cancer .

HY-W015780S

1,4-Dimethoxybenzene-d10
1,4-Dimethoxybenzene-d₁₀ is the deuterium labeled 1,4-Dimethoxybenzene . 1,4-Dimethoxybenzene is an endogenous metabolite.

HY-Y0566S

1,4-Diazabicyclo[2.2.2]octane-d12
1,4-Diazabicyclo[2.2.2]octane-d₁₂ is the deuterium labeled 1,4-Diazabicyclo[2.2.2]octane .

HY-W102449S

4-Acetyl-N-methylaniline-13C,d3
4-Acetyl-N-methylaniline- ¹³C,d₃ (1-(4-(Methylamino)phenyl)ethanone- ¹³C,d₃ ) is a ¹³C and deuterated isotope of 4-Acetyl-N-methylaniline .

HY-W414805S

Prometon-d14
Prometon-d₁₄ is the deuterium labeled Prometon .

HY-W019816S

S-Ethyl dipropylthiocarbamate-d14
S-Ethyl dipropylthiocarbamate-d₁₄ is the deuterium labeled S-Ethyl dipropylthiocarbamate .

HY-10585AS1

Valproic acid-d14 sodium

Valproic acid-d₁₄ (sodium) is deuterium labeled Valproic acid (sodium). Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

HY-146895S

14:0 Lyso PC-d27
14:0 Lyso PC-d₂₇ is deuterium labeled 14:0 Lyso PC.

HY-W015784S

1,4-Benzenedimethanol-d4
1,4-Benzenedimethanol-d₄ is the deuterium labeled 1,4-Benzenedimethanol .

HY-W157316S

1,4-bUtanedithiol-d8
1,4-bUtanedithiol-d₈ is the deuterium labeled 1,4-bUtanedithiol .

HY-Y0496S

1,4-Dichlorobenzene-d4

1,4-Dichlorobenzene-d₄ is the deuterium labeled 1,4-Dichlorobenzene. 1,4-Dichlorobenzene is a non-genotoxic, orally active mitogenic/tumor-promoting carcinogen that is also widely used as a dye, resin intermediate, and deodorant, moth repellent/insecticide. 1,4-Dichlorobenzene induces liver tumors in mice and promotes the growth of spontaneous precancerous lesions, but shows no liver tumor-inducing activity in F344 rats. 1,4-Dichlorobenzene increases the levels of white blood cell count, serum alanine aminotransferase and blood urea nitrogen in occupationally exposed populations. 1,4-Dichlorobenzene is metabolized to 2,5-dichlorophenol and excreted in urine, and this metabolite can serve as a biomarker for 1,4-Dichlorobenzene exposure. Due to its specific hepatotoxic characteristics, 1,4-Dichlorobenzene is applicable to liver cancer-related research .

HY-146880S

14:0-14:0 PC-d27
14:0-14:0 PC-d₂₇ is deuterium labeled 14:0-14:0 PC.

HY-130239S

14(S)-HDHA-d5
14(S)-HDHA-d₅ (14(S)-HDoHE-d₅) is deuterium labeled 14(S)-HDHA. 14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway .

HY-146912S

14:0-16:1-14:0 TG-d5
14:0-16:1-14:0 TG-d₅ is deuterium labeled 14:0-16:1-14:0 TG.

HY-B2229S

Sulbutiamine-d14
Sulbutiamine-d₁₄ is deuterated labeled Sulbutiamine.

HY-101400S

Deoxycytidine triphosphate-d14 dilithium
Deoxycytidine triphosphate-d₁₄ (dCTP-d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate-d₁₄) dilithium is deuterium labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-B0623S

Ropinirole-d14
Ropinirole-d₁₄ is the deuterium labeled Ropinirole .

HY-143664S

(±)14(15)-DiHET-d11
(±)14,15-DiHETrE-d₁₁ ((±)14(15)-DiHET-d₁₁) is the deuterium labeled (±)14,15-DiHETrE (HY-143664). (±)14,15-DiHETrE is an epoxide hydrolases enzymatically hydrated metabolite of (±)14(15)-EET .

HY-W013053S

Dibenz[a,h]anthracene-d14
Dibenz[a,h]anthracene-d₁₄ is the deuterium Dibenz[a,h]anthracene.

HY-W707528

Propofol-d14
Propofol-d₁₄ (2,6-Diisopropylphenol-d₁₄) is the deuterium labeled Propofol (HY-B0649). Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic .

HY-125818S4

Cytidine-5'-triphosphate-d14 dilithium

Cytidine-5'-triphosphate-d₁₄ (Cytidine triphosphate-d₁₄ dilithium; 5'-CTP-d₁₄) dilithium is deuterium labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.

HY-A0024AS

(Rac)-Tolterodine-d14 tartrate
(Rac)-Tolterodine-d₁₄ (tartrate) is the deuterium labeled (Rac)-Tolterodine tartrate .

HY-136648S3

2'-Deoxyadenosine-5'-triphosphate-d14 dilithium
2'-Deoxyadenosine-5'-triphosphate-d₁₄ (dATP-d₁₄) dilithium is deuterium labeled 2'-Deoxyadenosine-5'-triphosphate (HY-136648). 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.

HY-W009659S

m-Terphenyl-d14
m-Terphenyl-d₁₄ is the deuterium labeled m-Terphenyl .

HY-132645S

(Rac)-Tolterodine-d14 hydrochloride
(Rac)-Tolterodine-d₁₄ (hydrochloride) is the deuterium labeled (Rac)-Tolterodine hydrochloride .

HY-146919S

(4E,14Z)-Sphingadiene-d7
4E,14Z-Sphingadiene-d₇ is deuterium labeled 4E,14Z-Sphingadiene.

HY-101400S1

Deoxycytidine triphosphate-15N3,d14 dilithium

Deoxycytidine triphosphate- ¹⁵N₃,d₁₄ (dCTP- ¹⁵N₃,d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃,d₁₄) dilithium is deuterium and ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-143964S

Irbesartan impurity 14-d4

Irbesartan impurity 14-d₄ is the deuterium labeled Irbesartan impurity 14 . Irbesartan impurity 14-d₄ is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-144156S

7-Hydroxy Ropinirole-d14
7-Hydroxy Ropinirole-d₁₄ is the deuterium labeled 7-Hydroxy Ropinirole .

HY-138616S1

dGTP-d14 dilithium
dGTP-d₁₄ (2'-Deoxyguanosine-5'-triphosphate-d₁₄) dilithium is deuterium labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-146972S

Zearalenone-14-O-β-glucoside-13C6
Zearalenone-14-O-β-glucoside- ¹³C₆ is the ¹³C₆ labeled Zearalenone-14-O-β-glucoside.

HY-146774S

14:1 cholesteryl ester-d7
14:1 cholesteryl ester-d₇ is deuterium labeled 14:1 cholesteryl ester.

HY-W700950

1-(4-Chlorophenyl)cyclobutanecarbonitrile-d6
1-(4-Chlorophenyl)cyclobutanecarbonitrile-d₆ (1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile-d₆) is the deuterium labeled 1-(4-Chlorophenyl)cyclobutanecarbonitrile (HY-W010002).

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0083G

Betulin Trochol	Endogenous Metabolite Apoptosis Fatty Acid Synthase (FASN)	Cancer
Betulin (GMP) (Trochol (GMP)) is Betulin (HY-N0083) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC₅₀ of 14.5 μM in K562 cell line.

HY-13689G

Go 6983	PKC Histone Methyltransferase DNA Methyltransferase DNA/RNA Synthesis	Inflammation/Immunology
Go 6983 GMP is Go 6983 (HY-13689) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Go 6983 is a dual inhibitor targeting Suv39h1/2 (KMT1A/KMT1B) and PKC, as well as a transcriptional activator capable of inducing DNA hypomethylation. Go 6983 stimulates the transcription of *Prdm14* by reducing Suv39h1/2 protein levels, decreasing histone modifications in the *Prdm14* promoter region, and increasing the recruitment of RNA polymerase II. Go 6983 induces genome-wide DNA hypomethylation by inhibiting de novo methyltransferase expression and increasing Tet1/Tet2 levels, thereby promoting self-renewal and pluripotency maintenance of stem cells. Meanwhile, Go 6983 can block PKC-mediated signaling pathways to reduce the expression of EMT-related genes and eliminate the upregulation of antioxidant genes downstream of NRF2. Go 6983 is mainly used in mechanism studies related to myocardial ischemia/reperfusion injury .

HY-15149G

Romidepsin FK 228; FR 901228; NSC 630176	HDAC Apoptosis	Cancer
Romidepsin (GMP) (FK 228 (GMP)) is Romidepsin (HY-15149) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC₅₀s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively . Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis .

HY-110397G

KP-457	MMP	Cardiovascular Disease
KP-457 (GMP) is KP-457 (HY-110397) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture.KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC₅₀s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively .

HY-12879G

IWP-4	Wnt Casein Kinase	Cardiovascular Disease Neurological Disease Cancer
IWP-4 (GMP) is the GMP-grade form of IWP-4 (HY-12879). IWP-4 is a Wnt inhibitor with an IC₅₀ of 25 nM. IWP-4 specifically inhibits casein kinase 1δ/ε (CK1δ/ε), with an IC₅₀ of 1.06 μM against wild-type CK1δ, 1.02 μM against the CK1δ kinase domain, and 7.07 μM against CK1ε; it shows enhanced inhibitory activity against the M82F CK1δ mutant (IC₅₀ = 0.14 μM). IWP-4 is applicable to research related to cancer, Alzheimer's disease (AD), and heart failure .

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