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POM2/CELLULOSE SYNTHASE INTERACTIVE PROTEIN1

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2581

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65

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151

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229

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817

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25

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3

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y0703

    CMC-Na (Viscosity:800-1200 mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Sodium carboxymethyl cellulose (Viscosity:800-1200 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.
    Sodium carboxymethyl cellulose (Viscosity:800-1200 mPa.s)
  • HY-125861

    MC(Viscosity:100000mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Methyl cellulose (MC) (Viscosity:100000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:100000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction [1].
    Methyl cellulose(Viscosity:100000mPa.s)
  • HY-15870
    SR 11302
    20+ Cited Publications

    AP-1 Inflammation/Immunology Cancer
    SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE) [1].
    SR 11302
  • HY-Y1889A

    CMC-Na (MW 250000); CMC-Na (Viscosity:1500-3100 mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Sodium carboxymethyl cellulose (CMC-Na) (MW 250000) is a sodium salt of carboxymethyl cellulose. Sodium carboxymethyl cellulose has adsorption and corrosion inhibition on low-carbon steel in an acidic medium. Sodium carboxymethyl cellulose can be used as a thickener, paste and barrier agent [1] [2] .
    Sodium carboxymethyl cellulose (MW 250000)
  • HY-125861E

    MC(Viscosity:4000mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Methyl cellulose (MC) (Viscosity:4000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:4000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction [1].
    Methyl cellulose(Viscosity:4000mPa.s)
  • HY-Y0703C

    CMC-Na (Viscosity:300-800mpa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Sodium carboxymethyl cellulose (Viscosity:300-800mpa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.
    Sodium carboxymethyl cellulose (Viscosity:300-800mpa.s)
  • HY-125861B
    Methyl cellulose(Viscosity:400mPa.s)
    2 Publications Verification

    MC(Viscosity:400mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Methyl cellulose (MC) (Viscosity:400mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:400mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction [1].
    Methyl cellulose(Viscosity:400mPa.s)
  • HY-Y0703A

    CMC-Na (Viscosity:1200-1400 mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Sodium carboxymethyl cellulose (Viscosity:1200-1400 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.
    Sodium carboxymethyl cellulose (Viscosity:1200-1400 mPa.s)
  • HY-Y1889

    CMC-Na (Viscosity:5000-15000 mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.
    Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s)
  • HY-Y0703D

    CMC-Na (average Mw 90000, DS=0.7, Viscosity:50-200 mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Sodium carboxymethyl cellulose (average Mw 90000, DS=0.7, Viscosity:50-200 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent [1] [2] .
    Sodium carboxymethyl cellulose (average Mw 90000)
  • HY-100557

    Environmental Pollutants Biochemical Assay Reagents Interleukin Related Metabolic Disease Inflammation/Immunology
    Hydroxypropyl Cellulose is an orally active cellulose ether and surfactant. Hydroxypropyl cellulose is divided into high-substituted HPC (HHPC) and low-substituted HPC (LHPC). Hydroxypropyl Cellulose reduces inflammatory mediators (IL-6, IL-1β). Hydroxypropyl Cellulose improves colitis and obesity. Hydroxypropyl Cellulose can be used as a pharmaceutical excipient, such as coating agent, emulsifier, suspension, tablet, thickener, viscosifier [1] [2] .
    Hydroxypropyl Cellulose
  • HY-B2221
    Cellulose
    1 Publications Verification

    Pectin glycosidase

    Environmental Pollutants Endogenous Metabolite Others Cancer
    Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food.
    Cellulose
  • HY-B2221C

    Carboxymethyl CELLULOSE CM-32; CM-32

    Environmental Pollutants Biochemical Assay Reagents Others
    CM Cellulose CM-32 (Carboxymethyl cellulose) is a cellulose derivative. CM Cellulose CM-32 has a wide range of applications in the biomedical field, including tissue engineering, wound dressing, absorbent nonwovens, fabrication of 3D-scaffolds for biocompatible implants, artificial organs or mimics of extracellular polymeric matrix and diagnosis of various diseases. CM Cellulose CM-32 can decrease osteoclasts formation. CM Cellulose CM-32 can be used as a biological material or organic compound for life science related research [1] [2].
    CM Cellulose CM-32
  • HY-125861A
    Methyl cellulose(Viscosity:15mPa.s)
    2 Publications Verification

    MC(Viscosity:15mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Methyl cellulose (MC) (Viscosity:15mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:15mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction [1].
    Methyl cellulose(Viscosity:15mPa.s)
  • HY-W115746

    Ethyl CELLULOSE N-200

    Environmental Pollutants Biochemical Assay Reagents Infection Cancer
    Ethyl cellulose is a derivative of cellulose. Ethyl cellulose is a non-toxic, biodegradable polymer. Ethyl cellulose has unique properties such as oil gel formation, active ingredient delivery and film formation. Ethyl cellulose can be used as a pharmaceutical excipient, such as a coating agent, flavoring agent, tablet filler, etc. Ethyl cellulose can be used to prepare nanoparticles for active compound delivery [1] [2] .
    Ethyl cellulose
  • HY-110177
    SP-100030
    1 Publications Verification

    NF-κB Inflammation/Immunology
    SP-100030 is a potent NF-κB and activator protein-1 (AP-1) double inhibitor (IC50s=50 and 50 nM, respectively). SP-100030 inhibits IL-2, IL-8, and TNF-alpha production in Jurkat and other T cell lines. SP-100030 decreases murine collagen-induced arthritis (CIA) [1] [2].
    SP-100030
  • HY-17013
    Dofequidar
    2 Publications Verification

    MS-209 free base

    P-glycoprotein Cancer
    Dofequidar (MS-209 free base) is an orally active quinoline compoundthat blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). Dofequidar has highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar competitively inhibits ABCB1/P-gp, ABCC1/MRP-1, blocks the efflux of chemotherapeutic agents, increases the drug concentration in cancer cells, and enhances the chemotherapeutic effect [1] [2].
    Dofequidar
  • HY-125861C
    Methyl cellulose(Viscosity:1500mPa.s)
    2 Publications Verification

    MC(Viscosity:1500mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Methyl cellulose (MC) (Viscosity:1500mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:1500mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction [1].
    Methyl cellulose(Viscosity:1500mPa.s)
  • HY-B0780
    Fimasartan
    4 Publications Verification

    BR-A-657

    Angiotensin Receptor Apoptosis NF-κB Cardiovascular Disease Neurological Disease Inflammation/Immunology Endocrinology
    Fimasartan (BRA-657) is an orally effective angiotensin receptor AT1 non-peptide antagonist. Fimasartan has antihypertensive effects. Fimasartan improves neuroinflammation and brain injury mediated by NLRP3 inflammatome after intracerebral hemorrhage, and has neuroprotective effect. Fimasartan inhibits the expression of inducible nitric oxide synthase through the inactivation of NF-κB and activator protein-1 [1] [2] .
    Fimasartan
  • HY-128577
    NIC3
    1 Publications Verification

    BTB/POZ Family Cancer
    NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity [1].
    NIC3
  • HY-157068

    Ferroptosis Glutathione Peroxidase Cancer
    icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation, in synergism with GPX4 inhibition. icFSP1 induces ferroptosis. icFSP1 shows antitumor activity against melanoma. [1].
    icFSP1
  • HY-125864B

    MMP Cadherin Cardiovascular Disease Neurological Disease
    Murine Fibrinogen is a native fibrinogen derived from mouse plasma. Murine Fibrinogen acts as a cerebrovascular permeability enhancer. Murine Fibrinogen activates matrix metalloproteinase-9 (MMP-9), downregulates the expression of vascular endothelial cadherin (VE-cadherin), and upregulates the expression of plasmalemmal vesicle-associated protein-1 (PV-1). Murine Fibrinogen increases macromolecular leakage from pial veins, thereby disrupting the microvascular integrity of cerebral blood vessels. Murine Fibrinogen can be used in studies related to cerebrovascular dysfunction [1].
    Murine Fibrinogen
  • HY-152927

    Biochemical Assay Reagents Others
    Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility agents. Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) exhibits no acute/subchronic/chronic toxicity in rats, with oral activity and LD50 >2.5 g/kg [1].
    Hydroxypropylmethyl cellulose acetate succinate (Mw:20-100 kDa)
  • HY-120959

    Fluorescent Dye Parasite Others
    DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1].
    DAUDA
  • HY-W046325

    Diethylaminoethyl CELLULOSE

    Biochemical Assay Reagents Others
    DEAE-Cellulose (Diethylaminoethyl cellulose), a common biopolymer derivative. DEAE-Cellulose is a weakly basic cellulose anion exchanger [1].
    DEAE-Cellulose
  • HY-W010983
    SC-236
    2 Publications Verification

    COX PPAR Apoptosis Cardiovascular Disease Inflammation/Immunology Cancer
    SC-236 is an orally active COX-2 specific inhibitor (IC50 = 10 nM) and a PPARγ agonist. SC-236 suppresses activator protein-1 (AP-1) through c-Jun NH2-terminal kinase. SC-236 exerts anti-inflammatory effects by suppressing phosphorylation of ERK in a murine model [1] [2] .
    SC-236
  • HY-17013A
    Dofequidar fumarate
    2 Publications Verification

    MS-209

    P-glycoprotein Cancer
    Dofequidar fumarate (MS-209) is an orally active quinoline compoundthat blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). Dofequidar fumarate has highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar fumarate competitively inhibits ABCB1/P-gp, ABCC1/MRP-1, blocks the efflux of chemotherapeutic agents, increases the drug concentration in cancer cells, and enhances the chemotherapeutic effect [1] [2].
    Dofequidar fumarate
  • HY-B2221B1

    Biochemical Assay Reagents Others
    Hydroxyethyl cellulose, Viscosity (2%):150mPa.s is a thickening agent. Hydroxyethyl cellulose, Viscosity(2%):150mPa.s is a kind of biological materials or organic compounds that are widely used in life science research [1].
    Hydroxyethyl cellulose, Viscosity(2%):150mPa.s
  • HY-125861D
    Methyl cellulose(Viscosity:40000mPa.s)
    2 Publications Verification

    MC(Viscosity:40000mPa.s)

    Environmental Pollutants Biochemical Assay Reagents Others
    Methyl cellulose (MC) (Viscosity:40000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:40000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction [1].
    Methyl cellulose(Viscosity:40000mPa.s)
  • HY-19964
    Potassium clavulanate cellulose
    2 Publications Verification

    Potassium clavulanate:CELLULOSE (1:1)

    Beta-lactamase Bacterial Antibiotic Infection
    Potassium clavulanate cellulose (Potassium clavulanate:cellulose (1:1)) is a mixture of potassium clavulanate and cellulose, is a bacterial β-lactamase inhibitor. Clavulanate potassium is a form of Clavulanic acid. Clavulanate potassium fights bacteria that resistant to penicillins and other antibiotics. Potassium clavulanate with the combination of amoxicillin can be used for the research of different infections caused by bacteria, such as sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin [1] [2].
    Potassium clavulanate cellulose
  • HY-W145498

    Cellotetraose

    Drug Metabolite Others
    D-(+)-Cellotetraose (Cellotetraose) is a primary hydrolysis product of cellulose [1].
    D-(+)-Cellotetraose
  • HY-N1915

    Endogenous Metabolite Metabolic Disease
    Cellohexaose is a glucose polymer with two or more glucose monomers produced from the breakdown of cellulose, consisting of a condensation of beta (1-4) linked D-glucose monomers [1].
    Cellohexaose
  • HY-B2221S4

    Endogenous Metabolite Isotope-Labeled Compounds Others
    U-sup>13C Cellulose high DP from maize (high purity) is the 13C labeled Cellulose [1].
    U-13C Cellulose high DP from maize (high purity)
  • HY-Y0703E

    Biochemical Assay Reagents Others
    Sodium carboxymethyl cellulose (Viscosity:2500-6000mpa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent [1].
    Sodium carboxymethyl cellulose (Viscosity:2500-6000mpa.s)
  • HY-144267

    Glucosylceramide Synthase (GCS) Neurological Disease Metabolic Disease
    Glucosylceramide synthase-IN-2 (compound T-690) is a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC50s of 15 nM and 190 nM for human GCS and mouse GCS, respectively.Glucosylceramide synthase-IN-2 exhibits noncompetitive type inhibition with C8-ceramide and UDP-glucose.Glucosylceramide synthase-IN-2 can be used for Gaucher's disease research [1].
    Glucosylceramide synthase-IN-2
  • HY-144266

    Glucosylceramide SYNTHASE-IN-1

    Glucosylceramide Synthase (GCS) Neurological Disease Metabolic Disease
    Glucosylceramide synthase-IN-1 (T-036), a chemical probe, a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC50s of 31 nM and 51 nM for human GCS and mouse GCS, respectively. Glucosylceramide synthase-IN-1 can be used for Gaucher's disease research [1].
    TP-060
  • HY-W14549

    Cellotriose

    Drug Intermediate Others
    D-(+)-Cellotriose (Cellotriose) is an oligosaccharide, it is an intermediate in the enzyme hydrolysis of cellulose [1].
    D-(+)-Cellotriose
  • HY-125861H

    MC(Viscosity:25mPa.s)

    Biochemical Assay Reagents Others
    Methyl cellulose (MC) (Viscosity:25mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:25mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction [1].
    Methyl cellulose(Viscosity:25mPa.s)
  • HY-122228

    Cellulose Synthase Others
    Cestrin is a plant cellulose synthase complex (CESA) trafficking inhibitor. Cestrin selectively blocks the sustained trafficking of cellulose synthase complexes (CSCs) and the interaction between CSC and POM2, which indirectly causes secondary destabilization of cortical microtubules (MTs). Cestrin reduces cellulose content, inhibits anisotropic cell growth, induces cell swelling and decreases cell elongation. Cestrin is applicable to plant cell biology research [1].
    Cestrin
  • HY-N4231

    NF-κB Inflammation/Immunology
    Lucyoside B inhibits the production of inflammatory mediators via both NF-κB and activator protein-1 pathways in activated macrophages [1].
    Lucyoside B
  • HY-E70425

    Glycosyltransferase Metabolic Disease
    Sucrose synthase belongs to glycosyltransferases and is a reversible catalyst present in plants, which catalyzes the conversion of sucrose into fructose and UDP-G or ADP-G. Sucrose synthase localizes to the cytoplasm, plasma membrane, cell wall, vacuole and mitochondria of plants. Sucrose synthase regulates sugar metabolism, supports the development of taproots, fruits, seeds and vascular tissues, drives the synthesis of starch, cellulose and callose, and enhances nitrogen fixation capacity. Sucrose synthase mediates signal transduction in plant meristems. Sucrose synthase is associated with plant growth, anaerobic stress tolerance, as well as shoot apical meristem and leaf morphology; overexpression of this enzyme promotes plant growth, increases xylem size, and elevates cellulose and starch contents [1] [2].
    Sucrose synthase
  • HY-15450A
    INCB 3284
    2 Publications Verification

    CCR Endocrinology
    INCB 3284 is a potent, selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2, with an IC50 of 3.7 nM. INCB 3284 can be used in the research of acute liver failure.
    INCB 3284
  • HY-15870A

    AP-1 Inflammation/Immunology Cancer
    (6E)-SR 11302 is a E-isomer of SR 11302. SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE) [1].
    (6E)-SR 11302
  • HY-173463

    Sirtuin Metabolic Disease Inflammation/Immunology
    Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity. Sirtuin modulator 8 significantly downregulates the expression of monocyte chemoattractant protein-1 (MCP-1) and upregulates the expression of fibroblast growth factor 21 (FGF21). Sirtuin modulator 8 regulates the expression of inflammation- and metabolism-related genes, showing potential for studying metabolic diseases (such as diabetes, obesity) and inflammatory diseases [1].
    Sirtuin modulator 8
  • HY-B2221B2

    Biochemical Assay Reagents Others
    Hydroxyethyl cellulose, Viscosity (2%):40000mPa.s is a thickening agent. Hydroxyethyl cellulose, Viscosity(2%):40000mPa.s is a kind of biological materials or organic compounds that are widely used in life science research [1].
    Hydroxyethyl cellulose, Viscosity(2%):40000mPa.s
  • HY-B2221B3

    Biochemical Assay Reagents Others
    Hydroxyethyl cellulose, Viscosity (2%):6000mPa.s is a thickening agent. Hydroxyethyl cellulose, Viscosity(2%):6000mPa.s is a kind of biological materials or organic compounds that are widely used in life science research [1].
    Hydroxyethyl cellulose, Viscosity(2%):6000mPa.s
  • HY-W011602R

    Biochemical Assay Reagents Reference Standards Others
    Triethyl citrate (Standard) is the analytical standard of Triethyl citrate. This product is intended for research and analytical applications. Triethyl citrate is an?ester?of?citric acid. Triethyl citrate can be?used as a?plasticizer?for cellulosic plastic-based nanocomposites [1].
    Triethyl citrate (Standard)
  • HY-B2220B

    Endogenous Metabolite Others
    Thermostable cellulase recombinant is a cellulose hydrolase present in hyperthermophiles, which catalyzes the hydrolysis of β-1,4 glycosidic bonds in cellulose. Thermostable cellulase recombinant targets carboxymethyl cellulose (CMC) as its primary substrate, and retains high residual activity even after incubation at high temperatures. The activity of Thermostable cellulase recombinant is inhibited by ionic and non-ionic detergents, and can be enhanced by cobalt ions. Thermostable cellulase recombinant can be applied in the paper industry [1].
    Thermostable cellulase (recombinant)
  • HY-N5118

    (-)-Chimonanthine

    Tyrosinase Cancer
    Chimonanthine is an alkaloid of Chimonanthus praecox, inhibits tyrosinase and tyrosine-related protein-1 mRNA expression, amd inhibits melanogenesis [1].
    Chimonanthine
  • HY-B2221S2

    Isotope-Labeled Compounds Others
    U-sup>13C Cellulose high DP from wheat is the cellulose (HY-B2221) isolated from wheat, that is consist of abundant glucose and all the carbon atoms are labeled with isotope 13C [1].
    U-13C Cellulose high DP from wheat

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